Details of Disease

General Information of Disease (ID: DIS6V60A)

Disease Name	Recurrent adult burkitt lymphoma
Synonyms	colon Burkitts lymphoma; colon Burkitt lymphoma; Burkitt lymphoma of colon; Burkitts lymphoma of colon; colon Burkitt's lymphoma; primary colon Burkitt's lymphoma
Disease Class	2A85: Mature B-cell lymphoma
Definition	A rare Burkitt lymphoma that arises from the colon.
Disease Hierarchy	DIS9D5XU: Burkitt lymphoma DISZYIBJ: Familial colorectal cancer DISIT4DK: Immune system cancer DIS16P0O: Colon lymphoma DIS6V60A: Recurrent adult burkitt lymphoma
ICD Code	ICD-11 ICD-11: 2A85.6 ICD-10 ICD-10: C83.7, C91.8
Disease Identifiers	MONDO ID MONDO_0006150 UMLS CUI C1333083 MedGen ID 272491

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 12 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Allopurinol	DMLPAOB	Approved	Small molecular drug	[1]
Bortezomib	DMNO38U	Approved	Small molecular drug	[2]
Fludarabine	DMVRLT7	Approved	Small molecular drug	[3]
Gemcitabine	DMSE3I7	Approved	Small molecular drug	[4]
Lenalidomide	DM6Q7U4	Approved	Small molecular drug	[5]
Mycophenolate mofetil	DMPQAGE	Approved	Small molecular drug	[6]
Mycophenolic acid	DMRBMAU	Approved	NA	[7]
Rasburicase	DMAXT7T	Approved	NA	[7]
Rituximab	DM1YVZT	Approved	Antibody	[8]
Tacrolimus	DMZ7XNQ	Approved	Small molecular drug	[9]
Thalidomide	DM70BU5	Approved	Small molecular drug	[10]
Vidarabine	DM0N85H	Approved	Small molecular drug	[11]
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⏷ Show the Full List of 12 Drug(s)

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CPI-613	DM5XUQL	Phase 3	Small molecular drug	[12]
CD19 CAR T-cells	DMJCT6Q	Phase 1	CAR T Cell Therapy	[13]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Allopurinol FDA Label
2	Bortezomib FDA Label
3	Fludarabine FDA Label
4	Gemcitabine FDA Label
5	Lenalidomide FDA Label
6	Mycophenolate mofetil FDA Label
7	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
8	Burkitt lymphoma - no impact of HIV status on outcomes with rituximab-based chemoimmunotherapy. Leuk Lymphoma. 2023 Mar;64(3):586-596.
9	Tacrolimus FDA Label
10	Thalidomide FDA Label
11	Vidarabine FDA Label
12	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
13	ClinicalTrials.gov (NCT02443831) CARPALL: Immunotherapy With CD19 CAR T-cells for CD19+ Haematological Malignancies