Details of Disease

General Information of Disease (ID: DISEW817)

• Disease Name: Hepatobiliary disorder
• Synonyms: liver and biliary tract disease; liver and biliary system disorder; liver and biliary disorder; liver and biliary disease; hepatobiliary system disease or disorder; hepatobiliary system disease; hepatobiliary disorder; disorder of hepatobiliary system; disease or disorder of hepatobiliary system; disease of hepatobiliary system
• Definition: A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma.
• Disease Hierarchy:
  DISWD40R: Disease
  DIS7JDYJ: Gastrointestinal disease
  DISEW817: Hepatobiliary disorder
• Disease Identifiers:
  MONDO ID: MONDO_0002515
  MESH ID: D004066
  UMLS CUI: C0267792
  MedGen ID: 82758

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
FECH	TTQ6VF4	Strong	Genetic Variation	[1]

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
FBN2	OT3KYJQL	moderate	Biomarker	[2]
TJP2	OTQUY6BV	Strong	Biomarker	[3]

References

• [1] Biochemical abnormality in erythropoietic protoporphyria: cause and consequences.J Pediatr Gastroenterol Nutr. 2006 Jul;43 Suppl 1:S36-40. doi: 10.1097/01.mpg.0000226388.56612.fa.
• [2] Opisthorchis viverrini Draft Genome - Biomedical Implications and Future Avenues.Adv Parasitol. 2018;101:125-148. doi: 10.1016/bs.apar.2018.05.005. Epub 2018 Jun 6.
• [3] TJP2 hepatobiliary disorders: Novel variants and clinical diversity.Hum Mutat. 2020 Feb;41(2):502-511. doi: 10.1002/humu.23947. Epub 2019 Nov 28.