Details of Disease

General Information of Disease (ID: DISFGDES)

Disease Name Sciatica
Synonyms neuralgia, sciatic; sciatic Neuralgias; neuralgias, sciatic; sciatic neuralgia; bilateral sciaticas; sciatica, bilateral; bilateral sciatica
Disease Class ME84: Spinal pain
Definition
A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of sciatic neuropathy; radiculopathy (involving the spinal nerve roots; L4, L5, S1, or S2, often associated with intervertebral disk displacement); or lesions of the cauda equina.
Disease Hierarchy
DISMGDKX: Sciatic neuropathy
DISWO58J: Neuralgia
DISFGDES: Sciatica
ICD Code
ICD-11
ICD-11: ME84.3
ICD-10
ICD-10: M54.3
Expand ICD-11
'ME84.3
Expand ICD-10
'M54.3
Disease Identifiers
MONDO ID
MONDO_0024333
MESH ID
D012585
UMLS CUI
C0036396
MedGen ID
19893
HPO ID
HP:0011868
SNOMED CT ID
23056005

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Etanercept DMCV109 Approved Monoclonal antibody [1]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Placulumab DM56PDG Phase 1/2 Monoclonal antibody [2]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6789).
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016097)