General Information of Disease (ID: DISMGDKX)

Disease Name Sciatic neuropathy
Definition
Disease or damage involving the SCIATIC NERVE, which divides into the PERONEAL NERVE and TIBIAL NERVE (see also PERONEAL NEUROPATHIES and TIBIAL NEUROPATHY). Clinical manifestations may include SCIATICA or pain localized to the hip, PARESIS or PARALYSIS of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. The sciatic nerve may be affected by trauma; ISCHEMIA; COLLAGEN DISEASES; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1363)
Disease Hierarchy
:
DISMGDKX: Sciatic neuropathy
Disease Identifiers
MONDO ID
MONDO_0006960
MESH ID
D020426
UMLS CUI
C0149940
MedGen ID
57705
SNOMED CT ID
52585001

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 65 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCC8 TTP835K Strong Biomarker [1]
ABCC9 TTEF5MJ Strong Biomarker [1]
AGT TT5C0UB Strong Biomarker [2]
APOA1 TT5S8DR Strong Biomarker [3]
APOE TTKS9CB Strong Biomarker [3]
BDKRB1 TTG5QIA Strong Biomarker [4]
BDKRB2 TTGY8IW Strong Biomarker [4]
BDNF TTSMLOH Strong Therapeutic [5]
C3 TTJGY7A Strong Biomarker [6]
CACNA1D TT7RGTM Strong Biomarker [7]
CACNA1H TTZPWGN Strong Biomarker [8]
CACNA1I TTQZFTH Strong Biomarker [8]
CALCA TTVSFJW Strong Therapeutic [9]
CAPN1 TT1WBIJ Strong Biomarker [10]
CAPN2 TTG5QB7 Strong Biomarker [10]
CASP3 TTPF2QI Strong Biomarker [11]
CASP7 TTM7Y45 Strong Biomarker [11]
CASP8 TT6SZNG Strong Biomarker [11]
CAV1 TTXUBN2 Strong Biomarker [12]
CCL5 TT9DWLC Strong Biomarker [13]
CDKN1B TTLGFVW Strong Biomarker [14]
CNR2 TTMSFAW Strong Therapeutic [15]
CREB1 TTH4AN3 Strong Biomarker [16]
CRH TTA7YIZ Strong Biomarker [17]
CX3CR1 TT2T98G Strong Therapeutic [18]
CYP11A1 TTSYVO6 Strong Biomarker [19]
CYP17A1 TTRA5BZ Strong Biomarker [20]
FGFR1 TTRLW2X Strong Biomarker [21]
GDNF TTF23ML Strong Biomarker [22]
GFRA3 TT63XRS Strong Biomarker [22]
GRIN1 TTLD29N Strong Biomarker [23]
GRIN2B TTN9D8E Strong Biomarker [23]
GSK3B TTRSMW9 Strong Biomarker [24]
HMGB1 TTWQYB7 Strong Therapeutic [25]
HRH3 TT9JNIC Strong Biomarker [26]
ICAM1 TTA1L39 Strong Biomarker [27]
KCNC4 TTODZF1 Strong Biomarker [28]
KCNJ11 TT329V4 Strong Biomarker [29]
LAMP2 TTULDG7 Strong Therapeutic [30]
LRP1 TTF2V7I Strong Biomarker [23]
MAG TT9XFON Strong Therapeutic [31]
MC4R TTD0CIQ Strong Biomarker [32]
NFKBIA TTSHAEB Strong Therapeutic [33]
NGFR TTEDJN4 Strong Biomarker [34]
NRG1 TTEH395 Strong Therapeutic [35]
OPRL1 TTNT7K8 Strong Biomarker [36]
PCNA TTLG1PD Strong Biomarker [37]
PCSK5 TTPFWHU Strong Biomarker [38]
PDGFRA TT8FYO9 Strong Biomarker [39]
PDGFRB TTI7421 Strong Biomarker [39]
PLAT TTXAGYU Strong Biomarker [40]
PLAU TTGY7WI Strong Therapeutic [41]
PTAFR TTQL5VC Strong Biomarker [42]
PTN TTA9EJK Strong Biomarker [43]
RARA TTW38KT Strong Biomarker [44]
RARB TTISP28 Strong Biomarker [44]
REG3A TTL4H8N Strong Biomarker [45]
RGMA TTURJV4 Strong Biomarker [46]
RPSA TTLUW5B Strong Biomarker [47]
RXRA TT6PEUO Strong Biomarker [44]
SCN10A TT90XZ8 Strong Biomarker [48]
SERPINE1 TTTO43N Strong Therapeutic [49]
TLR4 TTISGCA Strong Biomarker [50]
TNFRSF1A TTG043C Strong Biomarker [51]
TNFRSF1B TT63WSF Strong Biomarker [51]
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⏷ Show the Full List of 65 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC17A7 DTNK0FR Strong Biomarker [52]
SLC17A8 DTAGDH7 Strong Biomarker [52]
------------------------------------------------------------------------------------
This Disease Is Related to 3 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
HSD3B1 DERDQWN Strong Biomarker [53]
NMNAT1 DE4D159 Strong Biomarker [54]
QARS1 DEVSTRI Strong Biomarker [55]
------------------------------------------------------------------------------------
This Disease Is Related to 29 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AKAP12 OTCVRDDX Strong Biomarker [56]
AMIGO3 OTIX9POY Strong Biomarker [57]
CASP12 OTY2W6FG Strong Biomarker [11]
CRCP OT4K9BT7 Strong Biomarker [58]
DBN1 OTZVKG8A Strong Biomarker [59]
ELAVL4 OT3YH6J6 Strong Biomarker [60]
FUBP1 OT77SC9N Strong Biomarker [61]
GFRA1 OT3WBVYB Strong Biomarker [62]
IL6R OTCQL07Z Strong Biomarker [63]
JAM3 OTX0F9QL Strong Biomarker [64]
KARS1 OT0EU4SV Strong Biomarker [55]
KCNJ8 OTZ8G8FE Strong Biomarker [1]
MAP2 OT6UYT3X Strong Biomarker [65]
MPZ OTAR2YXH Strong Therapeutic [66]
MYH4 OT4657W4 Strong Therapeutic [67]
NEFH OTMSCW5I Strong Therapeutic [68]
NEFL OTQESJV4 Strong Biomarker [69]
NEFM OT8VCBNF Strong Biomarker [69]
NLGN2 OTHDYL3H Strong Biomarker [70]
NLGN3 OTKDEC1Q Strong Biomarker [70]
NOS1AP OTDFOBRU Strong Biomarker [71]
NTS OTPGDNQS Strong Biomarker [72]
PMP22 OTXWYWCZ Strong Biomarker [73]
PPARGC1A OTHCDQ22 Strong Biomarker [74]
RAN OT2TER5M Strong Biomarker [75]
RANBP1 OTQE226K Strong Biomarker [75]
RANGAP1 OTZGD3LJ Strong Biomarker [75]
RCHY1 OTAE7504 Strong Biomarker [14]
SNW1 OTKWG3PS Strong Biomarker [76]
------------------------------------------------------------------------------------
⏷ Show the Full List of 29 DOT(s)

References

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2 Application of angiotensin II to healthy rat sciatic nerve can produce neuropathy without associated vasculopathy.Muscle Nerve. 2010 Dec;42(6):959-65. doi: 10.1002/mus.21767. Epub 2010 Sep 30.
3 A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.J Clin Invest. 1989 Mar;83(3):1015-31. doi: 10.1172/JCI113943.
4 Role of kinin B1 and B2 receptors in a rat model of neuropathic pain.Int Immunopharmacol. 2008 Feb;8(2):188-96. doi: 10.1016/j.intimp.2007.09.009. Epub 2007 Sep 29.
5 Substrate-mediated nanoparticle/gene delivery to MSC spheroids and their applications in peripheral nerve regeneration.Biomaterials. 2014 Mar;35(9):2630-41. doi: 10.1016/j.biomaterials.2013.12.021. Epub 2014 Jan 2.
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8 Upregulation of T-type Ca2+ channels in primary sensory neurons in spinal nerve injury.Spine (Phila Pa 1976). 2013 Mar 15;38(6):463-70. doi: 10.1097/BRS.0b013e318272fbf8.
9 Effects of 660-nm gallium-aluminum-arsenide low-energy laser on nerve regeneration after acellular nerve allograft in rats.Synapse. 2010 Feb;64(2):152-60. doi: 10.1002/syn.20724.
10 Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles.Acta Histochem. 2014 Jun;116(5):936-42. doi: 10.1016/j.acthis.2014.03.006. Epub 2014 Apr 16.
11 Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury.Neuroreport. 2018 Jun 13;29(9):779-785. doi: 10.1097/WNR.0000000000001031.
12 Peripheral nerve injury alters blood-spinal cord barrier functional and molecular integrity through a selective inflammatory pathway.J Neurosci. 2011 Jul 27;31(30):10819-28. doi: 10.1523/JNEUROSCI.1642-11.2011.
13 Human amniotic fluid mesenchymal stem cells in combination with hyperbaric oxygen augment peripheral nerve regeneration.Neurochem Res. 2009 Jul;34(7):1304-16. doi: 10.1007/s11064-008-9910-7. Epub 2009 Jan 17.
14 Dynamic changes of PIRH2 and p27kip1 expression in injured rat sciatic nerve.Neurol Sci. 2012 Aug;33(4):749-57. doi: 10.1007/s10072-011-0809-8. Epub 2011 Sep 30.
15 Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.Pain. 2009 Jun;143(3):206-212. doi: 10.1016/j.pain.2009.02.018. Epub 2009 Apr 3.
16 Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats.PLoS One. 2009 Nov 12;4(11):e7820. doi: 10.1371/journal.pone.0007820.
17 Experimental neuropathy increases limbic forebrain CRF.Eur J Pain. 2012 Jan;16(1):61-71. doi: 10.1016/j.ejpain.2011.05.016.
18 Intrathecal infusion of pyrrolidine dithiocarbamate for the prevention and reversal of neuropathic pain in rats using a sciatic chronic constriction injury model.Reg Anesth Pain Med. 2010 May-Jun;35(3):231-7. doi: 10.1097/AAP.0b013e3181df245b.
19 Neurogenic pain and steroid synthesis in the spinal cord.J Mol Neurosci. 2006;28(1):17-31. doi: 10.1385/jmn:28:1:17.
20 Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord.FASEB J. 2008 Jan;22(1):93-104. doi: 10.1096/fj.07-8930com. Epub 2007 Aug 24.
21 Expression of fibroblast growth factor-2 and fibroblast growth factor receptor 1 messenger RNAs in spinal ganglia and sciatic nerve: regulation after peripheral nerve lesion.Neuroscience. 1997 Jan;76(1):123-35. doi: 10.1016/s0306-4522(96)00355-7.
22 Expression of glial cell line-derived neurotrophic factor family of growth factors in peripheral nerve injury in rats.Neuroreport. 2000 Jun 5;11(8):1651-4. doi: 10.1097/00001756-200006050-00011.
23 Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia.Brain Res. 2016 Jan 15;1631:157-64. doi: 10.1016/j.brainres.2015.11.041. Epub 2015 Dec 2.
24 Increased GSK-3 expression in DRG microglia in response to sciatic nerve crush.Acta Biochim Biophys Sin (Shanghai). 2016 Jun;48(6):581-3. doi: 10.1093/abbs/gmw027. Epub 2016 Apr 28.
25 Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1.PLoS One. 2013 Aug 21;8(8):e73640. doi: 10.1371/journal.pone.0073640. eCollection 2013.
26 Histaminergic involvement in neuropathic pain produced by partial ligation of the sciatic nerve in rats.Reg Anesth Pain Med. 2007 Mar-Apr;32(2):124-9. doi: 10.1016/j.rapm.2006.11.009.
27 Dynamic changes of ICAM-1 expression in peripheral nervous system following sciatic nerve injury.Neurol Res. 2011 Jan;33(1):75-83. doi: 10.1179/016164110X12714125204353. Epub 2010 Jun 11.
28 Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivity.J Neurosci. 2007 Sep 12;27(37):9855-65. doi: 10.1523/JNEUROSCI.0604-07.2007.
29 Alterations in the expression of ATP-sensitive potassium channel subunit mRNA after acute peripheral nerve and spinal cord injury.Eur Neurol. 2007;57(1):4-10. doi: 10.1159/000097003. Epub 2006 Nov 14.
30 Effect of autophagy on allodynia, hyperalgesia and astrocyte activation in a rat model of neuropathic pain.Int J Mol Med. 2018 Oct;42(4):2009-2019. doi: 10.3892/ijmm.2018.3763. Epub 2018 Jul 6.
31 Myelin-associated glycoprotein reduces axonal branching and enhances functional recovery after sciatic nerve transection in rats.Glia. 2007 Nov 1;55(14):1498-507. doi: 10.1002/glia.20566.
32 Melanocortin 4 receptor induces hyperalgesia and allodynia after chronic constriction injury by activation of p38 MAPK in DRG.Int J Neurosci. 2012 Feb;122(2):74-81. doi: 10.3109/00207454.2011.630542. Epub 2011 Nov 24.
33 Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model.Eur J Pain. 2009 Sep;13(8):794-806. doi: 10.1016/j.ejpain.2008.09.009. Epub 2008 Oct 19.
34 The role of C-terminal binding protein 2 in Schwann cell differentiation after sciatic nerve crush.J Mol Neurosci. 2013 Mar;49(3):531-8. doi: 10.1007/s12031-012-9916-0. Epub 2012 Nov 9.
35 Secretion of EGF-like domain of heregulin promotes axonal growth and functional recovery of injured sciatic nerve.Mol Cells. 2010 Nov;30(5):477-84. doi: 10.1007/s10059-010-0137-5. Epub 2010 Oct 14.
36 Expression of ORL1 mRNA in some brain nuclei in neuropathic pain rats.Brain Res. 2005 May 10;1043(1-2):214-7. doi: 10.1016/j.brainres.2005.01.037.
37 Changes in CLIP3 expression after sciatic nerve injury in adult rats.J Mol Histol. 2012 Dec;43(6):669-79. doi: 10.1007/s10735-012-9450-y. Epub 2012 Sep 27.
38 The pro-protein convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF processing.Brain Res Mol Brain Res. 1998 Aug 31;59(2):229-46. doi: 10.1016/s0169-328x(98)00141-7.
39 Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves.J Peripher Nerv Syst. 2009 Sep;14(3):165-76. doi: 10.1111/j.1529-8027.2009.00228.x.
40 The role and mechanism of the up-regulation of fibrinolytic activity in painful peripheral nerve injury.Neurochem Res. 2009 Mar;34(3):587-92. doi: 10.1007/s11064-008-9826-2. Epub 2008 Aug 21.
41 Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA.Evid Based Complement Alternat Med. 2011;2011:378907. doi: 10.1155/2011/378907. Epub 2010 Dec 1.
42 Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury.Mol Pain. 2012 Feb 2;8:8. doi: 10.1186/1744-8069-8-8.
43 Different pattern of pleiotrophin and midkine expression in neuropathic pain: correlation between changes in pleiotrophin gene expression and rat strain differences in neuropathic pain.Growth Factors. 2008 Feb;26(1):44-8. doi: 10.1080/08977190801987711.
44 Regulation of retinoic acid receptors alpha, beta and retinoid X receptor alpha after sciatic nerve injury.Neuroscience. 2006 Sep 15;141(4):1761-74. doi: 10.1016/j.neuroscience.2006.05.021. Epub 2006 Jun 19.
45 Patterns of pain: meta-analysis of microarray studies of pain.Pain. 2011 Aug;152(8):1888-1898. doi: 10.1016/j.pain.2011.04.014. Epub 2011 May 10.
46 Induction of repulsive guidance molecule in neurons following sciatic nerve injury.J Chem Neuroanat. 2006 Aug;32(1):74-7. doi: 10.1016/j.jchemneu.2006.06.001. Epub 2006 Jul 24.
47 Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury.J Neurotrauma. 2009 Feb 11;26(2):195-207. doi: 10.1089/neu.2008.0677.
48 Relationship of axonal voltage-gated sodium channel 1.8 (NaV1.8) mRNA accumulation to sciatic nerve injury-induced painful neuropathy in rats.J Biol Chem. 2011 Nov 18;286(46):39836-47. doi: 10.1074/jbc.M111.261701. Epub 2011 Sep 30.
49 Chinese tuina downregulates the elevated levels of tissue plasminogen activator in sciatic nerve injured Sprague-Dawley rats.Chin J Integr Med. 2017 Aug;23(8):617-624. doi: 10.1007/s11655-015-2142-1. Epub 2015 May 13.
50 Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats.Eur J Pharmacol. 2012 Feb 15;676(1-3):51-6. doi: 10.1016/j.ejphar.2011.11.037. Epub 2011 Dec 7.
51 Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors.J Neuroimmunol. 2001 Mar 1;114(1-2):48-56. doi: 10.1016/s0165-5728(00)00453-7.
52 Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens.Mol Brain. 2013 Jul 9;6:32. doi: 10.1186/1756-6606-6-32.
53 Increased expression of 3 beta-hydroxysteroid dehydrogenase mRNA in dorsal root ganglion neurons of adult rats following peripheral nerve injury.Neurosci Lett. 2003 Apr 3;340(1):45-8. doi: 10.1016/s0304-3940(03)00079-x.
54 Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.J Neurosci. 2006 Aug 16;26(33):8484-91. doi: 10.1523/JNEUROSCI.2320-06.2006.
55 Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury.J Mol Histol. 2015 Feb;46(1):115-22. doi: 10.1007/s10735-014-9601-4. Epub 2014 Dec 3.
56 A critical role of SRC-suppressed C kinase substrate in rat astrocytes after chronic constriction injury.Neuromolecular Med. 2010 Sep;12(3):205-16. doi: 10.1007/s12017-009-8093-y. Epub 2009 Nov 25.
57 AMIGO3 is an NgR1/p75 co-receptor signalling axon growth inhibition in the acute phase of adult central nervous system injury.PLoS One. 2013 Apr 16;8(4):e61878. doi: 10.1371/journal.pone.0061878. Print 2013.
58 Localization and modulation of calcitonin gene-related peptide-receptor component protein-immunoreactive cells in the rat central and peripheral nervous systems.Neuroscience. 2003;120(3):677-94. doi: 10.1016/s0306-4522(03)00159-3.
59 Drebrin expression is increased in spinal motoneurons of rats after axotomy.Neurosci Lett. 2001 Oct 5;311(3):165-8. doi: 10.1016/s0304-3940(01)02155-3.
60 Increased expression and localization of the RNA-binding protein HuD and GAP-43 mRNA to cytoplasmic granules in DRG neurons during nerve regeneration.Exp Neurol. 2003 Sep;183(1):100-8. doi: 10.1016/s0014-4886(03)00103-1.
61 FBP1 and p27kip1 expression after sciatic nerve injury: implications for Schwann cells proliferation and differentiation.J Cell Biochem. 2014 Jan;115(1):130-40. doi: 10.1002/jcb.24640.
62 Sciatic nerve injury in adult rats causes distinct changes in the central projections of sensory neurons expressing different glial cell line-derived neurotrophic factor family receptors.J Comp Neurol. 2010 Aug 1;518(15):3024-45. doi: 10.1002/cne.22378.
63 Satellite glial cells express IL-6 and corresponding signal-transducing receptors in the dorsal root ganglia of rat neuropathic pain model.Neuron Glia Biol. 2010 Feb;6(1):73-83. doi: 10.1017/S1740925X10000074. Epub 2010 Jun 2.
64 The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats.Brain Behav. 2012 Jul;2(4):402-14. doi: 10.1002/brb3.63.
65 Expression changes of parvalbumin and microtubule-associated protein 2 induced by chronic constriction injury in rat dorsal root ganglia.Chin Med J (Engl). 2011 Jul;124(14):2184-90.
66 Electrical stimulation enhances peripheral nerve regeneration after crush injury in rats.Mol Med Rep. 2013 May;7(5):1523-7. doi: 10.3892/mmr.2013.1395. Epub 2013 Mar 26.
67 BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury.Am J Physiol Cell Physiol. 2004 Jul;287(1):C22-9. doi: 10.1152/ajpcell.00583.2003. Epub 2004 Feb 18.
68 Thyroid hormones stimulate expression and modification of cytoskeletal protein during rat sciatic nerve regeneration.Brain Res. 2002 Dec 13;957(2):259-70. doi: 10.1016/s0006-8993(02)03607-7.
69 Insulin deficiency rather than hyperglycemia accounts for impaired neurotrophic responses and nerve fiber regeneration in type 1 diabetic neuropathy.J Neuropathol Exp Neurol. 2003 Mar;62(3):260-71. doi: 10.1093/jnen/62.3.260.
70 Down-regulation of mRNAs for synaptic adhesion molecules neuroligin-2 and -3 and synCAM1 in spinal motoneurons after axotomy.J Comp Neurol. 2007 Jul 10;503(2):308-18. doi: 10.1002/cne.21382.
71 Changes in mRNA for CAPON and Dexras1 in adult rat following sciatic nerve transection.J Chem Neuroanat. 2008 Jan;35(1):85-93. doi: 10.1016/j.jchemneu.2007.07.004. Epub 2007 Jul 31.
72 Chronic pain increases brainstem proneurotensin/neuromedin-N mRNA expression: a hybridization-histochemical and immunohistochemical study using three different rat models for chronic nociception.Brain Res. 1993 May 14;611(1):87-102. doi: 10.1016/s0006-8993(93)90001-4.
73 Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13).J Cell Biol. 1992 Apr;117(1):225-38. doi: 10.1083/jcb.117.1.225.
74 Salvianolic acid A protects the peripheral nerve function in diabetic rats through regulation of the AMPK-PGC1-Sirt3 axis.Molecules. 2012 Sep 20;17(9):11216-28. doi: 10.3390/molecules170911216.
75 Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve.Neuron. 2008 Jul 31;59(2):241-52. doi: 10.1016/j.neuron.2008.05.029.
76 Spatiotemporal expression of SKIP after rat sciatic nerve crush.Neurochem Res. 2013 Apr;38(4):857-65. doi: 10.1007/s11064-013-0990-7. Epub 2013 Feb 7.