Details of Disease

General Information of Disease (ID: DISH7JW9)

Disease Name Ileus
Synonyms ileus of intestine
Disease Class DA93: Small intestine motility disorder
Definition Decrease in peristalsis in the absence of a mechanical bowel obstruction.
Disease Hierarchy
DISE52WH: Intestinal obstruction
DISH7JW9: Ileus
ICD Code
ICD-11
ICD-11: DA93.0
ICD-10
ICD-10: K56.7
Expand ICD-11
'DA91; 'DB30
Expand ICD-10
'K56.7
Expand ICD-9
537.2,560.1,560.31,777.1,777.4
Disease Identifiers
MONDO ID
MONDO_0004567
MESH ID
D045823
UMLS CUI
C1258215
MedGen ID
219874
HPO ID
HP:0002595

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
TZP-101 DMOE582 Phase 2b Small molecular drug [1]
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This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
PYN-9 DM2BXI8 Preclinical NA [2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 4 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
GPS2 OT065FSS Limited Biomarker [3]
NID1 OTKLBLS6 Limited Biomarker [4]
TAPBP OTL81AVZ Limited Genetic Variation [5]
ERAS OT528IZO Strong Biomarker [6]
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3535).
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027027)
3 A high preoperative Glasgow prognostic score predicts a high likelihood of conversion from laparoscopic to open surgery in patients with colon cancer.Surg Endosc. 2019 Apr;33(4):1111-1116. doi: 10.1007/s00464-018-6369-8. Epub 2018 Jul 25.
4 Neuronal intestinal malformations: a retro- and prospective study on 203 patients.Eur J Pediatr Surg. 1994 Oct;4(5):279-86. doi: 10.1055/s-2008-1066118.
5 Redefining the implications of nasogastric tube placement following radical cystectomy in the alvimopan era.World J Urol. 2017 Apr;35(4):625-631. doi: 10.1007/s00345-016-1910-7. Epub 2016 Jul 30.
6 Increased incidence of prolonged ileus after colectomy for inflammatory bowel diseases under ERAS protocol: a cohort analysis.J Surg Res. 2017 May 15;212:86-93. doi: 10.1016/j.jss.2016.12.031. Epub 2016 Dec 29.