Details of Disease

Disease Name

Chancroids; Ulcus molle, skin

Definition

Chancroid is a bacterial infection that is spread through sexual contact. It is caused by a type of bacteria called Haemophilus ducreyi. Chancroid is characterized by a small bump on the genital which becomes a painful ulcer. Men may have just one ulcer, but women often develop four or more.About half of the people who are infected with a chancroid will develop enlarged inguinal lymph nodes, the nodes located in the fold between the leg and the lower abdomen. In some cases, the nodes will break through the skin and cause draining abscesses. The swollen lymph nodes and abscesses are often called buboes. Chancroid infections can be treated with antibiotics, including azithromycin, ceftriaxone, ciprofloxacin, and erythromycin. Large lymph node swellings need to be drained, either with a needle or local surgery.

Disease Hierarchy

DIS8ZVFW: Primary bacterial infectious disease

DISK46TO: Bacterial sexually transmitted disease

DISEM33Q: Infectious disease

DIS9JXH0: Haemophilus infectious disease

DISMVLOF: Chancroid

Disease Identifiers

MONDO ID

MONDO_0001797

MESH ID

D002602

UMLS CUI

C0007947

MedGen ID

872

SNOMED CT ID

266143009

General Information of Disease (ID: DISMVLOF)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 10 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Ceftriaxone	DMCEW64	Approved	Small molecular drug	[1]
Ciprofloxacin XR	DM2NLS9	Approved	Small molecular drug	[2]
Demeclocycline	DMZEPFJ	Approved	Small molecular drug	[3]
Doxycycline	DM7ICNU	Approved	Small molecular drug	[4]
Fusidic Acid	DMWVCF3	Approved	Small molecular drug	[2]
Minocycline	DMVN5OH	Approved	Small molecular drug	[5]
Norfloxacin	DMIZ6W2	Approved	Small molecular drug	[6]
Ofloxacin	DM0VQN3	Approved	Small molecular drug	[7]
Streptomycin	DME1LQN	Approved	Small molecular drug	[8]
Sulfisoxazole	DMXLT8C	Approved	Small molecular drug	[9]
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⏷ Show the Full List of 10 Drug(s)

This Disease is Treated as An Indication in 1 Drugs in Phase 3 Trial

Drug Name	Drug ID	Highest Status	Drug Type	REF
Azithromycin	DMS6UOE	Phase 3 Trial	Small molecular drug	[10]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Ceftriaxone FDA Label
2	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
3	Demeclocycline FDA Label
4	Doxycycline FDA Label
5	Minocycline FDA Label
6	Norfloxacin FDA Label
7	Ofloxacin FDA Label
8	Streptomycin FDA Label
9	Sulfisoxazole FDA Label
10	Azithromycin FDA Label