Details of Disease

General Information of Disease (ID: DISN1LGK)

• Disease Name: Escherichia coli meningitis
• Definition: A form of gram-negative meningitis that tends to occur in neonates, in association with anatomical abnormalities (which feature communication between the meninges and cutaneous structures) or as opportunistic infections in association with immunologic deficiency syndromes. In premature neonates the clinical presentation may be limited to anorexia; vomiting; lethargy; or respiratory distress. Full-term infants may have as additional features fever; seizures; and bulging of the anterior fontanelle. (From Menkes, Textbook of Child Neurology, 5th ed, pp398-400)
• Disease Hierarchy:
  DISRP9SL: Bacterial meningitis
  DISN1LGK: Escherichia coli meningitis
• Disease Identifiers:
  MONDO ID: MONDO_0006753
  MESH ID: D020814
  UMLS CUI: C0338395
  MedGen ID: 90920
  SNOMED CT ID: 192655005

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 4 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Amikacin	DM5PDRB	Approved	Small molecular drug	[1]
Ampicillin	DMHWE7P	Approved	Small molecular drug	[2]
Cefotaxime	DMEB837	Approved	NA	[3]
Ceftriaxone	DMCEW64	Approved	Small molecular drug	[4]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Amikacin FDA Label
• [2] Ampicillin FDA Label
• [3] Cefotaxime FDA Label
• [4] Ceftriaxone FDA Label