Details of Disease

General Information of Disease (ID: DISRN92I)

Disease Name Breast carcinoma in situ
Synonyms
breast cancer stage 0; breast in situ carcinoma; in situ breast cancer; non-infiltrating carcinoma of the breast; carcinoma in situ of the breast; stage 0 breast cancer aJCC v6 and v7; non-infiltrating breast carcinoma; non-invasive carcinoma of breast; breast carcinoma in situ; stage 0 breast carcinoma; stage 0 breast cancer aJCC v7; non-invasive carcinoma of the breast; non-infiltrating carcinoma of breast; stage 0 breast cancer aJCC v6; non-invasive breast carcinoma; carcinoma in situ of breast; breast cancer in situ; stage 0 carcinoma of the breast; stage 0 breast cancer; stage 0 breast carcinoma in situ; stage 0 carcinoma of breast
Definition A in situ carcinoma that involves the breast.
Disease Hierarchy
DIS13V4C: In situ carcinoma
DIS2UE88: Breast carcinoma
DISRN92I: Breast carcinoma in situ
Disease Identifiers
MONDO ID
MONDO_0004658
MESH ID
D000071960
UMLS CUI
C0154084
MedGen ID
57817
SNOMED CT ID
189336000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ACVR2A TTX2DRI Strong Genetic Variation [1]
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This Disease Is Related to 4 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
LYPD4 OTYNO8BS Strong Biomarker [2]
MAST2 OT85GLPP Strong Genetic Variation [1]
SSR1 OTQ6GDL2 Strong Biomarker [3]
TOX3 OTC9NR4W Strong Genetic Variation [4]
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References

1 A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium.Int J Cancer. 2018 Mar 15;142(6):1182-1188. doi: 10.1002/ijc.31145. Epub 2017 Nov 17.
2 Cause-specific mortality in women with breast cancer in situ.Int J Cancer. 2017 Jun 1;140(11):2414-2421. doi: 10.1002/ijc.30413. Epub 2016 Sep 19.
3 Modification of breast cancer risk in young women by a polymorphic sequence in the egfr gene.Cancer Res. 2004 Jan 1;64(1):7-12. doi: 10.1158/0008-5472.can-03-2623.
4 Genetic risk variants associated with in situ breast cancer.Breast Cancer Res. 2015 Jun 13;17(1):82. doi: 10.1186/s13058-015-0596-x.