Details of the Drug Combinations

General Information of This Drug (ID: DM15HL8)

Drug Name
Clindamycin   DM15HL8
Synonyms
Antirobe; CLDM; CLY; Chlolincocin; Chlorlincocin; Chlorodeoxylincomycin; Chlorolincomycin; Cleocin; ClindaDerm; Clindamicina; Clindamycine; Clindamycinum; Clinimycin; Dalacine; Klimicin; Sobelin; Zindaclin; Cleocin HCl; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clindamycine [French]; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; ResiDerm A; Klindan 300; U 21251; Cleocin (TN); Clindacin (TN); Clindamicina [INN-Spanish]; Clindamycin & Interleukin 12; Clindamycin & VRC3375; Clindamycine [INN-French]; Clindamycinum [INN-Latin]; Dalacin (TN); Evoclin (TN); U-21251; CLINDA & IL-12; Clindamycin (USAN/INN); Clindamycin [USAN:BAN:INN]; U-21,251; 7(S)-Chloro-7-deoxylincomycin; 7-CDL; 7-Chloro-7-deoxylincomycin; 7-Chlorolincomycin; 7-Deoxy-7(S)-chlorolincomycin
Indication
Disease Entry ICD 11 Status REF
Acne vulgaris ED80 Approved [1]
Aspiration pneumonia N.A. Approved [2]
Bacteremia 1A73 Approved [2]
Bacterial vaginosis MF3A Approved [2]
Pleural empyema N.A. Approved [2]
Staphylococcal pneumonia N.A. Approved [2]
Staphylococcus aureus infection N.A. Approved [2]
Streptococcal pneumonia N.A. Approved [2]
Pelvic inflammatory disease GA05 Investigative [2]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

84 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Clindamycin DCEB6FA Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Clindamycin DC8MJYR Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Clindamycin DCUAZGM Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atovaquone + Clindamycin DCCIX13 Atovaquone Hepatoblastoma (Cell Line: HB3) [3]
Bafilomycin A1 + Clindamycin DCCKVZR Bafilomycin A1 DD2 (Cell Line: DD2) [3]
Berberine + Clindamycin DCJ05KV Berberine DD2 (Cell Line: DD2) [3]
Berberine + Clindamycin DCEIT2X Berberine Hepatoblastoma (Cell Line: HB3) [4]
BGT226 + Clindamycin DCFR6B5 BGT226 DD2 (Cell Line: DD2) [3]
BGT226 + Clindamycin DCIWZMI BGT226 Hepatoblastoma (Cell Line: HB3) [4]
Biperiden + Clindamycin DC68P2I Biperiden DD2 (Cell Line: DD2) [3]
Biperiden + Clindamycin DCEQX0R Biperiden Hepatoblastoma (Cell Line: HB3) [4]
BIX-01294 + Clindamycin DCB5LFJ BIX-01294 DD2 (Cell Line: DD2) [3]
BIX-01294 + Clindamycin DC6961M BIX-01294 Hepatoblastoma (Cell Line: HB3) [4]
BRL-15572 + Clindamycin DCFSHOX BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Clindamycin DCBCGFJ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Pentostatin DCG6YKQ Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Gefitinib DC308A4 Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Lumefantrine DCAQN5E Lumefantrine DD2 (Cell Line: DD2) [3]
Clindamycin + Epinephrine DCS79VQ Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Triapine DCUREVL Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Acitretin DCZ2C99 Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Pepstatin DCKCGE2 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Chlorzoxazone DCQY79O Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Sulfinpyrazone DCNJCQC Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Armodafinil DCDAJHU Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + PF-02545920 DCMOSYH PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Lubiprostone DCPJR1G Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Tiagabine DC7DZMY Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + GINKGOLIDE A DCRZKKS GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Diazoxide DCWZBL6 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Benserazide DCTVE27 Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Pargyline DCWIIIK Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Bortezomib DCLQ18H Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Methylene blue DC2Z2PX Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Methylene blue DCAWF6D Methylene blue DD2 (Cell Line: DD2) [3]
Clindamycin + Ethinyl estradiol DCY4OEG Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Mesalazine DCDE76B Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Leflunomide DC9ZW9N Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Brincidofovir DC1PFFM Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Chloroquine DCW1CYV Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Chloroquine DC1DV29 Chloroquine Hepatoblastoma (Cell Line: HB3) [3]
Clindamycin + Hyodeoxycholic acid DC66LBL Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Asenapine DC6ZW9E Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Piperaquine DCWDFCY Piperaquine DD2 (Cell Line: DD2) [3]
Clindamycin + Piperaquine DC8P8XE Piperaquine Hepatoblastoma (Cell Line: HB3) [3]
Clindamycin + Endoxifen DCKMNIT Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Mycophenolic acid DCAZDHG Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Pyronaridine DC0AZA6 Pyronaridine DD2 (Cell Line: DD2) [3]
Clindamycin + Pyronaridine DCCAVH8 Pyronaridine Hepatoblastoma (Cell Line: HB3) [3]
Clindamycin + Mefloquine DCEW26U Mefloquine DD2 (Cell Line: DD2) [3]
Clindamycin + Cerivastatin DCKZD84 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Atovaquone DCANWII Atovaquone DD2 (Cell Line: DD2) [3]
Clindamycin + Atovaquone DCITQZH Atovaquone Hepatoblastoma (Cell Line: HB3) [3]
Cytarabine + Clindamycin DCOHPQV Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diethylcarbamazine + Clindamycin DCW07A5 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Eltanexor oral + Clindamycin DCB5PUV Eltanexor oral Hepatoblastoma (Cell Line: HB3) [4]
Ethinyl estradiol + Clindamycin DCVRH80 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fenoprofen + Clindamycin DCUG3K5 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Clindamycin DC4DIXM Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Gentian violet + Clindamycin DCM38C4 Gentian violet Hepatoblastoma (Cell Line: HB3) [4]
GSK2126458 + Clindamycin DCUEU55 GSK2126458 DD2 (Cell Line: DD2) [3]
GSK2126458 + Clindamycin DC4X3OG GSK2126458 Hepatoblastoma (Cell Line: HB3) [4]
Itraconazole + Clindamycin DCRL3XB Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Clindamycin DC2WGX7 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Clindamycin DC4LIW1 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Clindamycin DCNW5EQ Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methotrexate + Clindamycin DCJC8XV Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Clindamycin DCPQ7EA Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Clindamycin DCGSUS9 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
NITD609 + Clindamycin DCS120I NITD609 Hepatoblastoma (Cell Line: HB3) [4]
Nitrosoglutathione + Clindamycin DCG3KF5 Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Panobinostat + Clindamycin DCZ9HUE Panobinostat DD2 (Cell Line: DD2) [3]
PMID28460551-Compound-2 + Clindamycin DC7MHKU PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Proguanil + Clindamycin DCA2T8C Proguanil DD2 (Cell Line: DD2) [3]
Proguanil + Clindamycin DC2QJW9 Proguanil Hepatoblastoma (Cell Line: HB3) [3]
Quinine + Clindamycin DCRBSE5 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Quinine + Clindamycin DC09ZY7 Quinine Hepatoblastoma (Cell Line: HB3) [3]
Sapanisertib + Clindamycin DC3ZSBN Sapanisertib Hepatoblastoma (Cell Line: HB3) [4]
Topotecan + Clindamycin DCPK3JL Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Tranylcypromine + Clindamycin DC10B7U Tranylcypromine Hepatoblastoma (Cell Line: HB3) [3]
Trichostatin A + Clindamycin DC2Y639 Trichostatin A DD2 (Cell Line: DD2) [3]
Trichostatin A + Clindamycin DC8OTQR Trichostatin A Hepatoblastoma (Cell Line: HB3) [4]
Vinblastine + Clindamycin DC7VPAB Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Clindamycin DC36ADU Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 84 DrugCom(s)
6 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Clindamycin + Mifepristone DC3NV7U Mifepristone Retained Products After Miscarriage [5]
Clindamycin + Vancomycin DCFZ98T Vancomycin Pre-Diabetes [6]
Clindamycin + Cefazolin DC17GNA Cefazolin Supracondylar Humerus Fracture [7]
Clindamycin + Clotrimazole DC310V0 Clotrimazole Candidiasis [8]
Clindamycin + Flucloxacillin DCKLK02 Flucloxacillin Cellulitis [9]
Clindamycin + Cefazolin DCVPHSM Cefazolin Burn [10]
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⏷ Show the Full List of 6 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Clindamycin FDA Label
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
5 ClinicalTrials.gov (NCT04751500) The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC
6 ClinicalTrials.gov (NCT02730962) Interventional Bioremediation of Microbiota in Metabolic Syndrome
7 ClinicalTrials.gov (NCT03261830) Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
8 ClinicalTrials.gov (NCT02860845) Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections
9 ClinicalTrials.gov (NCT01876628) Adjunctive Clindamycin for Cellulitis: C4C Trial.
10 ClinicalTrials.gov (NCT04516148) A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting