Details of the Drug Combinations

General Information of This Drug (ID: DM2DMPO)

Drug Name

Kanamycin DM2DMPO

Synonyms

Aspidium; KAN; Kanamicina; Kanamycine; Kanamycinum; Kantrex; Klebcil; KANAMYCIN A; Kanamicina [Italian]; Kanamycin A tetracation; Kanamycin Base; Kanamycin monosulfate; Kanamycin sulfate; Kenamycin A; Liposomal Kanamycin; KM (the Antibiotic); Kanamycin [INN:BAN]; Kanamycin monosulfate (JP15); Kanamycinsulfate (JP15); Kanamycin sulfate (TN); Kanamycin sulfate (USP); Kanamycine [INN-French]; Kanamycinum [INN-Latin]; Kantrex (TN); Kantrex (1:1 sulfate); Klebcil (1:1 sulfate); O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine; O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy-D-streptamine; (1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside; (1S,2R,3R,4S,6R)-4,6-diamino-3-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside; (1S,2R,3R,4S,6R)-4,6-diazaniumyl-3-(6-azaniumyl-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-azaniumyl-3-deoxy-alpha-D-glucopyranoside; (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-alpha-D-glucoside; 4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside

Indication

Disease Entry	ICD 11	Status	REF
Bacteremia	1A73	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Cholangitis	N.A.	Approved	[1]
Urinary tract infection	GC08	Approved	[1]
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Therapeutic Class

Antibiotics

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

98 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acarbose + Kanamycin	DCHNW5L	Acarbose	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Aliskiren + Kanamycin	DC8BMMQ	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Amodiaquine + Kanamycin	DC04F16	Amodiaquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Aprepitant + Kanamycin	DCS6NP9	Aprepitant	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Auranofin + Kanamycin	DCU5PFS	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
BIO-300 + Kanamycin	DCYEGWQ	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Bortezomib + Kanamycin	DCIPQZ2	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Brincidofovir + Kanamycin	DC83O26	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Carglumic acid + Kanamycin	DCMNF6E	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Chloroquine + Kanamycin	DC0QXF0	Chloroquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Cilostazol + Kanamycin	DC59B49	Cilostazol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Citalopram + Kanamycin	DCCSWJK	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dihydroergotamine + Kanamycin	DC0QKCY	Dihydroergotamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Diphenidol + Kanamycin	DCOEKTK	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Dopamine + Kanamycin	DCK7BIR	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Doxapram + Kanamycin	DCW8NPD	Doxapram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Epinephrine + Kanamycin	DCJGTRN	Epinephrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ethinyl estradiol + Kanamycin	DCVHM1T	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
ETHISTERONE + Kanamycin	DC7D3J2	ETHISTERONE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Etomidate + Kanamycin	DC7Y0OH	Etomidate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Everolimus + Kanamycin	DCOFGNB	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ezetimibe + Kanamycin	DCAW8W0	Ezetimibe	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Fomepizole + Kanamycin	DC5GTAA	Fomepizole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Galantamine + Kanamycin	DCVQF0K	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Hyodeoxycholic acid + Kanamycin	DCBK2AS	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Isoproterenol + Kanamycin	DCNDTIB	Isoproterenol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Baclofen	DCSTZA5	Baclofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Bepridil	DCP6VTZ	Bepridil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Triamterene	DCP0VVJ	Triamterene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Crotamiton	DCYYKID	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Chlorphenesin	DC6V6T2	Chlorphenesin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Trioxsalen	DCH4ABI	Trioxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Anamorelin	DCC9RWX	Anamorelin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Testosterone	DCWCCTQ	Testosterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Pepstatin	DC6O8IN	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Pamidronate	DCRL085	Pamidronate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Itraconazole	DCJ3NLI	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Chlorzoxazone	DCBQ0IX	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Docetaxel	DCZ0Z9R	Docetaxel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Daidzin	DCTTFZ6	Daidzin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Sitagliptin	DCA1E3E	Sitagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Dichlorphenamide	DCVG8PO	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Clopidogrel	DCJ33P5	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Diphenidol	DCM90UP	Diphenidol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Eflornithine	DCQDFYL	Eflornithine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Tiagabine	DCVB9DI	Tiagabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Diazoxide	DCNB0FU	Diazoxide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Probenecid	DCR0UUD	Probenecid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Methylene blue	DCKHAMG	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Artemisinin	DCOGZYY	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Olanzapine	DCLMPJY	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Brincidofovir	DCQRAVB	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Chlormezanone	DC4G0O7	Chlormezanone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Endoxifen	DC3MSHE	Endoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Mycophenolic acid	DCJXPJD	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Fosfomycin	DCU6ESN	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Doxorubicin	DC2U4OP	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Estramustine	DCS3U5X	Estramustine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Cerivastatin	DCPAFFR	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Busulfan	DCPE6GA	Busulfan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Hydroxychloroquine	DCABGRP	Hydroxychloroquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Aciclovir	DCOM9UO	Aciclovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Enoxacin	DC0KZ2P	Enoxacin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + AS-1949490	DCHKC18	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Kanamycin + Tetracycline	DC0Q7VJ	Tetracycline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
L-165041 + Kanamycin	DC3VPDN	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Lefaxin + Kanamycin	DCZV3GJ	Lefaxin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Linagliptin + Kanamycin	DC15VHJ	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Maprotiline + Kanamycin	DCS14AY	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mebutamate + Kanamycin	DCHPD64	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Mefloquine + Kanamycin	DC4KBHF	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Metformin + Kanamycin	DC2Z0KO	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Methylergonovine + Kanamycin	DCV64DZ	Methylergonovine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
ML323 + Kanamycin	DCPMN1A	ML323	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Naringenin + Kanamycin	DCMFFXI	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Nitisinone + Kanamycin	DCEO1PP	Nitisinone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentamidine + Kanamycin	DCQ49R8	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pentostatin + Kanamycin	DC893MI	Pentostatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PF-02545920 + Kanamycin	DCGJO36	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
PMID28460551-Compound-2 + Kanamycin	DCYBKN9	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Primidone + Kanamycin	DC6FHTA	Primidone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Pyrazinamide + Kanamycin	DCV0TNH	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Quinine + Kanamycin	DCQFO0I	Quinine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ramelteon + Kanamycin	DCM6HMX	Ramelteon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Rifampin + Kanamycin	DC26W4D	Rifampin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
SCH 727965 + Kanamycin	DCAQGOP	SCH 727965	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Silver sulfadiazine + Kanamycin	DC1LUJO	Silver sulfadiazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Sorafenib + Kanamycin	DCYRMY6	Sorafenib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Spironolactone + Kanamycin	DCO96RQ	Spironolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tacrine + Kanamycin	DCWQU6X	Tacrine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tamoxifen + Kanamycin	DCNYAZ2	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tolvaptan + Kanamycin	DCDOS4K	Tolvaptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Tranexamic acid + Kanamycin	DCSYKUW	Tranexamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trihexyphenidyl + Kanamycin	DCCICD6	Trihexyphenidyl	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Trimethobenzamide + Kanamycin	DCXNV18	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Ursodeoxycholic acid + Kanamycin	DC227KQ	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Vinblastine + Kanamycin	DCDP3MO	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
Vorinostat + Kanamycin	DCTMTZ3	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[3]
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⏷ Show the Full List of 98 DrugCom(s)

References

1	Kanamycin FDA Label
2	Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8.
3	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.