General Information of This Drug (ID: DM62IPN)

Drug Name
Tenofovir disoproxil   DM62IPN
Synonyms
Tenofovir (Disoproxil); Tenofovir disoproxil; 201341-05-1; 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine; Bis(POC)PMPA; PMPA prodrug; CHEBI:63717; F4YU4LON7I; UNII-F4YU4LON7I; [[(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-(isopropoxycarbonyloxymethoxy)phosphoryl]oxymethyl isopropyl carbonate; tenofovir bis(isopropyloxycarbonyloxymethyl) ester
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

19 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Tenofovir disoproxil + Emtricitabine DC1OKMA Emtricitabine Acute HIV Infection [1]
Tenofovir disoproxil + Lamivudine DC10B31 Lamivudine Lymphoma [2]
Tenofovir disoproxil + Efavirenz DC5OIQZ Efavirenz HIV [3]
Tenofovir disoproxil + Maraviroc DC89Z0H Maraviroc HIV Infection [4]
Tenofovir disoproxil + Emtricitabine DCSMP7W Emtricitabine HIV Infection [4]
Tenofovir disoproxil + Efavirenz DC4AW4F Efavirenz HIV Infections [5]
Tenofovir disoproxil + Efavirenz DCA8U4I Efavirenz HIV Infections [5]
Tenofovir disoproxil + Nevirapine DCJWKXM Nevirapine HIV Infections [5]
Tenofovir disoproxil + Emtricitabine DCEVAH6 Emtricitabine HIV [6]
Tenofovir disoproxil + GS-9620 DCTYYX4 GS-9620 Chronic Hepatitis B [7]
Tenofovir disoproxil + Emtricitabine DC688W3 Emtricitabine Human Immunodeficiency Virus-type 1 Infection [8]
Tenofovir disoproxil + Emtricitabine DC8CXAS Emtricitabine Human Immunodeficiency Virus-type 1 Infection [8]
Tenofovir disoproxil + Dolutegravir DCGF49Z Dolutegravir Infection, Human Immunodeficiency Virus [9]
Tenofovir disoproxil + Efavirenz DCZLM62 Efavirenz HIV Infections [10]
Tenofovir disoproxil + Alendronate DC3CY1A Alendronate Bone Demineralization [11]
Tenofovir disoproxil + Telbivudine DCCGKED Telbivudine Hepatitis B, Chronic [12]
Tenofovir disoproxil + Entecavir DCEY6WC Entecavir Chronic Hepatitis B [13]
Tenofovir disoproxil + Maraviroc DCJJLVE Maraviroc HIV-1-infection [14]
Tenofovir disoproxil + Telbivudine DCRPXEI Telbivudine Chronic Hepatitis B [15]
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⏷ Show the Full List of 19 DrugCom(s)

References

1 ClinicalTrials.gov (NCT00734344) Pilot Study of Raltegravir/Truvada Versus Efavirenz/Truvada for Adults With Acute IV-1 Infection
2 ClinicalTrials.gov (NCT01528865) Safety & Efficacy of Lamivudine & Tenofovir to Lower Plasma Level of Viral RNA in Lymphoma
3 ClinicalTrials.gov (NCT02404259) PK TDF in Thai HIV-infected Children
4 ClinicalTrials.gov (NCT01505114) Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women
5 ClinicalTrials.gov (NCT00260078) Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children
6 ClinicalTrials.gov (NCT02904369) PK and PD Study of Oral F/TAF for HIV Prevention
7 ClinicalTrials.gov (NCT02579382) Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treated
8 ClinicalTrials.gov (NCT01709084) A Clinical Trial Comparing the Efficacy of Tenofovir Disoproxil Fumarate/Emtricitabine/Rilpivirine (TDF/FTC/RPV) Versus TDF/FTC/Efavirenz (TDF/FTC/EFV) in Patients With Undetectable Plasma HIV-1 RNA on Current First-line Treatment
9 ClinicalTrials.gov (NCT02831673) An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment nave HIV Infected Subjects (Gemini 1)
10 ClinicalTrials.gov (NCT02935075) Optimization of Antiretroviral Therapy
11 ClinicalTrials.gov (NCT02322099) Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss
12 ClinicalTrials.gov (NCT03468907) The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation
13 ClinicalTrials.gov (NCT03357822) A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B
14 ClinicalTrials.gov (NCT04965662) The Role of Home Packs of HIV PEPSE in High Risk Individuals
15 ClinicalTrials.gov (NCT02774837) Tenofovir Versus Tenofovir + Telbivudine for Chronic Hepatitis B