General Information of This Drug (ID: DM672AH)

Drug Name
Aspirin   DM672AH
Synonyms
ACETYLSALICYLIC ACID; 50-78-2; 2-Acetoxybenzoic acid; o-Acetoxybenzoic acid; O-Acetylsalicylic acid; Polopiryna; Acylpyrin; Ecotrin; Easprin; Acetylsalicylate; Acetophen; Acenterine; Acetosal; Colfarit; Salicylic acid acetate; o-Carboxyphenyl acetate; Enterosarein; Aspergum; Salcetogen; Pharmacin; Acetosalin; Premaspin; Micristin; Benaspir; Aspirdrops; Acetonyl; Aceticyl; Temperal; Acetylin; Empirin; Ecolen; Rhodine; Endydol; Saletin; Rheumintabletten; Solprin acid; Acidum acetylsalicylicum; Globentyl; Pravigard
Indication
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [1]
Adenomatous colon polyp N.A. Approved [1]
Back pain ME84.Z Approved [1]
Common cold CA00 Approved [1]
Headache 8A80-8A84 Approved [1]
Migraine disorder N.A. Approved [1]
Myocardial infarction BA41-BA43 Approved [2]
Osteoarthritis FA00-FA05 Approved [1]
Pain MG30-MG3Z Approved [3]
Cardiovascular disease BA00-BE2Z Phase 3 [3]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2/3 [4]
Colon cancer 2B90.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Analgesics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Aspirin + Marizomib DCX3E16 Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [5]
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75 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Aspirin + Bivalirudin DCC89IY Bivalirudin Coronary Artery Disease [6]
Aspirin + Clopidogrel DCQH23M Clopidogrel Atrial Fibrillation [7]
Aspirin + Minocycline DC17BGU Minocycline Bipolar Disorder Depression [8]
Aspirin + Bivalirudin DC2KC8W Bivalirudin Coronary Artery Disease [6]
Aspirin + Osimertinib DC4ZNYM Osimertinib Non-Small Cell Lung Cancer Stage IIIB [9]
Aspirin + Pseudoephedrine DC7XZOK Pseudoephedrine Common Cold [10]
Aspirin + Clopidogrel DCC6XJC Clopidogrel Cerebrovascular Accident [11]
Aspirin + Eflornithine DCOLXYT Eflornithine Adenomatous Polyp [12]
Aspirin + Clopidogrel DCVBZBK Clopidogrel Acute Coronary Disease [13]
Aspirin + CYTISINE DCVEKJP CYTISINE [14]
Aspirin + Ketorolac DCVG0VA Ketorolac Postoperative Pain, Acute [15]
Aspirin + Hydroxyurea DCYWQ39 Hydroxyurea Thrombocythemia [16]
Aspirin + Esomeprazole DC82N1Y Esomeprazole Peptic ulcer [17]
Aspirin + Naproxen DCDSOUO Naproxen Hematology [18]
Atorvastatin + Aspirin DC6H6B8 Atorvastatin Hypertension [19]
Brilinta + Aspirin DCIVTKZ Brilinta De Novo Stenosis [20]
Brilinta + Aspirin DCSMUT0 Brilinta Antiplatelet Drug [21]
Brilinta + Aspirin DC1YHVU Brilinta Inhibition on Platelet Aggregation [22]
Brilinta + Aspirin DCD2Z4H Brilinta Coronary Artery Disease [23]
Celecoxib + Aspirin DCCD0PN Celecoxib Postoperative Pain, Acute [15]
Darexaban maleate + Aspirin DC5MGAN Darexaban maleate Pharmacodynamic Interaction [24]
Darexaban maleate + Aspirin DCFHP3E Darexaban maleate Pharmacodynamic and Pharmacokinetic Interaction [25]
Darexaban maleate + Aspirin DCHH0VW Darexaban maleate Pharmacodynamic Interaction [24]
Esomeprazole + Aspirin DCAJ1HN Esomeprazole Esophageal Cancer [26]
Exemestane + Aspirin DCN5C10 Exemestane Breast Neoplasms [27]
Fentanyl + Aspirin DCBOMDD Fentanyl Postoperative Pain [28]
Heparin + Aspirin DC517AV Heparin Soft Tissue Neoplasms [29]
Metformin + Aspirin DC04PHO Metformin Preeclampsia [30]
Prasugrel + Aspirin DCSAJI9 Prasugrel Coronary Artery Disease [31]
Progesterone + Aspirin DCRBHOT Progesterone Preeclampsia [32]
Simvastatin + Aspirin DCN066Z Simvastatin Hypertriglyceridemia [33]
Simvastatin + Aspirin DCUMD48 Simvastatin Hypertension, Pulmonary [34]
Temanogrel + Aspirin DCHL0RG Temanogrel Acute Coronary Syndrome [35]
Vorapaxar + Aspirin DC8A7QB Vorapaxar Cerebral Infarction [36]
Aspirin + Prednisolone DC2S2NT Prednisolone Infertility [37]
Aspirin + Eicosapentaenoic acid/docosa-hexaenoic acid DC6PB7N Eicosapentaenoic acid/docosa-hexaenoic acid Periodontitis [38]
Aspirin + Vinpocetine DCACVBV Vinpocetine Stroke [39]
Aspirin + Ponatinib DCKCDW7 Ponatinib Chronic Myeloid Leukemia, Chronic Phase [40]
Aspirin + Zileuton DCNCS1P Zileuton Tobacco Use Disorder [41]
Aspirin + Pantoprazole DCX1UOY Pantoprazole Psychosis [42]
Atorvastatin + Aspirin DCWEH63 Atorvastatin Acute Stroke [43]
Atorvastatin + Aspirin DCMIK6V Atorvastatin Human Immunodeficiency Virus [44]
Cyclophosphamide + Aspirin DCMFLGF Cyclophosphamide Colo-rectal Cancer [45]
DU-176B + Aspirin DC444VB DU-176B Peripheral Arterial Disease [46]
DU-176B + Aspirin DCMTCPA DU-176B SCAD [47]
Aspirin + Caffeine DCAMCIS Caffeine Migraine Disorders [48]
Aspirin + Rivaroxaban DCDSKNN Rivaroxaban Transcatheter Aortic Valve Replacement [49]
Aspirin + Aspirin DCSLS4O Aspirin Pulmonary Disease, Chronic Obstructive [50]
Aspirin + Sarpogrelate DCX5XDB Sarpogrelate Coronary Artery Disease [51]
Aspirin + Losartan DC582R9 Losartan Covid-19 [52]
Aspirin + Colchicine DC62SDX Colchicine Stroke [53]
Aspirin + Lamivudine DCKZ7JM Lamivudine Hepatocellular Carcinoma [54]
Aspirin + Acetaminophen DCM19B8 Acetaminophen Migraine Disorders [48]
Aspirin + Rivaroxaban DCS32O9 Rivaroxaban Aortic Valve Stenosis [55]
Atorvastatin + Aspirin DCZQG4U Atorvastatin Prostate Cancer [56]
Brilinta + Aspirin DCUMZH1 Brilinta Coronary Artery Disease (CAD) [57]
Prasugrel + Aspirin DCL3O61 Prasugrel Coronary Artery Disease [58]
Simvastatin + Aspirin DCFJ0RA Simvastatin Covid-19 [52]
Aspirin + Clopidogrel DC9DJGY Clopidogrel Acute Coronary Syndrome [59]
Aspirin + Aspirin DCN14WX Aspirin Coronary Syndrome [60]
Aspirin + Clopidogrel DCZZ2VC Clopidogrel Hypertension [61]
Aspirin + Colchicine DC87OZE Colchicine Acute Coronary Syndrome [62]
Aspirin + Rivaroxaban DCBOPA1 Rivaroxaban Coronary Artery Disease [63]
Aspirin + Beraprost DCHIZY7 Beraprost Type 2 Diabetes Mellitus [64]
Aspirin + Tirofiban DCIVIC7 Tirofiban Branch Atheromatous Disease [65]
Aspirin + Warfarin DCNUAO5 Warfarin Aortic Valve Stenosis [66]
Aspirin + FP-187 DCR07UL FP-187 Relapsing-Remitting Multiple Sclerosis [67]
Aspirin + Levofloxacin DCTW309 Levofloxacin Prostate Cancer [68]
Aspirin + Warfarin DCWWEL9 Warfarin Complications Due to Heart Valve Prosthesis [69]
Brilinta + Aspirin DC1FNAS Brilinta Stable Coronary Syndrome [70]
DU-176B + Aspirin DC3FDGY DU-176B Coronary Artery Disease [71]
Heparin + Aspirin DC1950E Heparin Pregnancy [72]
Heparin + Aspirin DCLV82T Heparin Thrombophilia With Recurrent Pregnancy Loss [73]
Prasugrel + Aspirin DCOQV2Q Prasugrel Coronary Artery Disease [63]
Vorapaxar + Aspirin DCYVSS2 Vorapaxar Myocardial Infarction [74]
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⏷ Show the Full List of 75 DrugCom(s)
1 Approved Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Esomeprazole + Aspirin DC4UZ5T Esomeprazole Cardiovascular disease [75]
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References

1 Aspirin FDA Label
2 Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4139).
4 Protective Effect of Aspirin on COVID-19 Patients (PEAC)
5 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
6 ClinicalTrials.gov (NCT02384070) Simplified Anti-Thrombotic Therapy for FFR
7 ClinicalTrials.gov (NCT05960721) Low-dose NOAC Versus GDMT After LAAO
8 ClinicalTrials.gov (NCT01429272) Minocycline and Aspirin in the Treatment of Bipolar Depression
9 ClinicalTrials.gov (NCT03543683) Combination of Osimertinib and Aspirin to Treat 1st Generation EGFR-TKI Resistance in NSCLC
10 ClinicalTrials.gov (NCT00963443) Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold
11 ClinicalTrials.gov (NCT00059306) Secondary Prevention of Small Subcortical Strokes Trial
12 ClinicalTrials.gov (NCT00983580) Acetylsalicylic Acid and Eflornithine in Treating Patients at High Risk for Colorectal Cancer
13 ClinicalTrials.gov (NCT00335452) Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
14 #N/A
15 ClinicalTrials.gov (NCT05994287) Pain Treatment With Combinations of NSAIDs
16 ClinicalTrials.gov (NCT00175838) Primary Thrombocythaemia 1 Trial
17 An overview of proton pump inhibitors. Gastroenterol Nurs. 2003 Sep-Oct;26(5):182-90.
18 ClinicalTrials.gov (NCT02229461) Naproxen Sodium/ASA Platelet Study
19 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
20 ClinicalTrials.gov (NCT05209412) Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions
21 ClinicalTrials.gov (NCT04971356) 1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon
22 ClinicalTrials.gov (NCT01744288) Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets
23 ClinicalTrials.gov (NCT00528411) A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With Aspirin
24 ClinicalTrials.gov (NCT01409616) To Evaluate Whether Acetyl Salicylic Acid (Aspirin), the Combination of Aspirin and Clopidogrel and Darexaban (YM150) Interact in Their Effects
25 ClinicalTrials.gov (NCT01424332) To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their Effects
26 ClinicalTrials.gov (NCT00357682) A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia
27 ClinicalTrials.gov (NCT01431053) Study of Aspirin and Exemestane as Adjuvant Treatment in Breast Cancer
28 ClinicalTrials.gov (NCT03128346) Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery
29 ClinicalTrials.gov (NCT01965002) Feasibility of ExAblate MRI Guided High Intensity Focused Ultrasound Tx of Soft Tissue Tumors
30 ClinicalTrials.gov (NCT05580523) Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial
31 ClinicalTrials.gov (NCT01589978) PROMUS Element Plus US Post-Approval Study
32 ClinicalTrials.gov (NCT00719537) Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia
33 ClinicalTrials.gov (NCT01486433) The Effect of Multiple Doses of Epanova on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects
34 ClinicalTrials.gov (NCT00384865) A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
35 ClinicalTrials.gov (NCT02419820) Dose-escalation, Repeated and Single Oral Dosing Study
36 ClinicalTrials.gov (NCT00684515) Trial to Assess the Safety of Vorapaxar in Japanese Subjects With Cerebral Infarction (P05005; MK-5348-017)
37 ClinicalTrials.gov (NCT03503227) The Value of Prednisolone With Aspirin Before Embryo Transfer in Intracytoplasmic Sperm Injection (ICSI) Cycles
38 ClinicalTrials.gov (NCT01976806) The Effects of DHA on Periodontitis
39 ClinicalTrials.gov (NCT02878772) Vinpocetine Inhibits NF-B-dependent Inflammation in Acute Ischemic Stroke Patients
40 ClinicalTrials.gov (NCT04160546) Study to Evaluate the Reinduction and Second Stop of TKI With Ponatinib in CML in Molecular Response (ResToP)
41 ClinicalTrials.gov (NCT02348203) Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers
42 ClinicalTrials.gov (NCT02685748) Aspirin in Young Psychotic Patients
43 ClinicalTrials.gov (NCT04824911) Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease
44 ClinicalTrials.gov (NCT02081638) Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study
45 ClinicalTrials.gov (NCT04534218) Regorafenib in Combination With Metronomic Chemotherapies, and Low-dose Aspirin in Metastatic Colorectal Cancer
46 ClinicalTrials.gov (NCT01802775) Edoxaban in Peripheral Arterial Disease
47 ClinicalTrials.gov (NCT05122455) Effects of Edoxaban on Platelet Aggregation
48 ClinicalTrials.gov (NCT02183688) Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients
49 ClinicalTrials.gov (NCT02556203) Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes
50 ClinicalTrials.gov (NCT05265299) Trial to Determine Effective Aspirin Dose in COPD
51 ClinicalTrials.gov (NCT02294643) Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study
52 ClinicalTrials.gov (NCT04343001) Coronavirus Response - Active Support for Hospitalised Covid-19 Patients. U.S. National Institutes of Health.
53 ClinicalTrials.gov (NCT05476991) Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis
54 ClinicalTrials.gov (NCT01936233) Clinical Study of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery
55 ClinicalTrials.gov (NCT02833948) Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)
56 ClinicalTrials.gov (NCT03819101) Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer
57 ClinicalTrials.gov (NCT01813435) GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation
58 ClinicalTrials.gov (NCT01598337) The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency
59 ClinicalTrials.gov (NCT05573958) To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome
60 ClinicalTrials.gov (NCT04990791) WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?
61 ClinicalTrials.gov (NCT02594410) Zainidip in Renal Artery Stenosis
62 ClinicalTrials.gov (NCT04949516) Mono Antiplatelet and Colchicine Therapy
63 ClinicalTrials.gov (NCT04006288) Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease
64 ClinicalTrials.gov (NCT02786979) Efficacy and Safety of Dorner Tablets and Aspirin for Prevention of Arteriosclerosis Progress in Type 2 Diabetes Mellitus Patients
65 ClinicalTrials.gov (NCT05310968) Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction
66 ClinicalTrials.gov (NCT03807921) Anticoagulation for Aortic Bioprosthesis (ANTIPRO)
67 ClinicalTrials.gov (NCT02090413) Phase 4 Study of Effect of Aspirin on Flushing in Dimethyl Fumarate-Treated Participants With Relapsing-Remitting Multiple Sclerosis
68 ClinicalTrials.gov (NCT02757365) Efficiency Study of Aspirin to Prevent the Occurrence of Prostate Cancer
69 ClinicalTrials.gov (NCT02022527) Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis
70 ClinicalTrials.gov (NCT03224923) A Novel Strategy For Personalized Long-Term Dual Antiplatelet Therapy (RAPID EXTEND PILOT STUDY)
71 ClinicalTrials.gov (NCT02567461) Edoxaban in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With Aspirin and Clopidogrel
72 ClinicalTrials.gov (NCT01917799) Aspirin, Heparin and Miscarriage
73 ClinicalTrials.gov (NCT02986594) Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
74 ClinicalTrials.gov (NCT02548650) Vorapaxar as an Add-On Antiplatelet Therapy in Patients With and Without Diabetes Mellitus
75 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015