Details of the Drug Combinations

General Information of This Drug (ID: DMCT2YF)

Drug Name
Emetine   DMCT2YF
Synonyms
Emetine hydrochloride; EMETINE; 14198-59-5; MLS000028478; SMR000058444; NSC-33669; NSC33669; Emetine monohydrochloride; Opera_ID_1460; Cephaeline methyl ether HCl; AC1O7FP4; SCHEMBL636599; CHEMBL513000; DTXSID80424947; MolPort-004-964-890; Cephaeline methyl ether hydrochloride; NSC752340; AKOS024374935; NSC-752340; ST51014995; Emetan,7',10,11-tetramethoxy-, dihydrochloride; Q-100155; 10-[((1R)-6,7-dimethoxy(1,2,3,4-tetrahydroisoquinolyl))methyl](10S,11aS,9R)-9- ethyl-2,3-dimethoxy-5,6,7,11a-tetrahydropiperidino[2,1-a]isoquinolin
Indication
Disease Entry ICD 11 Status REF
Hepatitis virus infection 1E50-1E51 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

137 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
10-hydroxycamptothecin + Emetine DCCJUF3 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acarbose + Emetine DCDYTZD Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohydroxamic Acid + Emetine DCFM0V1 Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acitretin + Emetine DCMB8EX Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Emetine DC8T8AO Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Atenolol + Emetine DCJO6C1 Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BGT226 + Emetine DCW67DS BGT226 DD2 (Cell Line: DD2) [2]
BHV-0223 + Emetine DCGI2CD BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Emetine DC09L6L Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Carglumic acid + Emetine DC4TZWT Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cerivastatin + Emetine DC5UJ30 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Emetine DCERMT7 Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + Emetine DC0MHP9 Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Emetine DC72ZR8 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Crotamiton + Emetine DCL6H0I Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Daidzin + Emetine DCSDBQI Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Emetine DCG9LQO Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dextromethorphan + Emetine DC6BMEV Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + Emetine DCU5PH4 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dichlorphenamide + Emetine DCJ3R99 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + Emetine DC23CKM Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dronedarone + Emetine DCXJ8VV Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Efavirenz + Emetine DC991TM Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eflornithine + Emetine DCGKB0P Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Ribavirin-TP DCNFX5X Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Mebutamate DCZ4CG2 Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Picoplatin DC6F2L1 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Baclofen DCXHXN6 Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Primidone DCZN8DC Primidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Acetazolamide DCZNBGZ Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Citalopram DC5BK3M Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Imipramine DCP7YYV Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Chlorphenesin DCMUSL2 Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Panobinostat DCJKGPY Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
Emetine + Anamorelin DCIZGD1 Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Everolimus DCN5ALW Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Dexmedetomidine DCV6V56 Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Tranexamic acid DC3BL9R Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + IT-141 DCLEU11 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Methylergonovine DCQPXEN Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Palonosetron DCINW0Z Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Berberine DCEC27D Berberine DD2 (Cell Line: DD2) [2]
Emetine + Guanfacine DC0OLMB Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + SCH 727965 DC7EWGO SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + K-134 DCIE0RK K-134 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Memantine DC7B67E Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Docetaxel DCETAUO Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Methoxsalen DCRSLDO Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Marizomib DCMAW42 Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
Emetine + Galantamine DC4USTP Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Ginsenoside Rb1 DC3I1JE Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Phensuximide DC8TPMZ Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Diphenidol DCKKNY3 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Bosentan DCOUN8T Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + BIO-300 DCBDQX4 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + PF-02545920 DCZSN3G PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Trazodone DCHKL4P Trazodone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Entacapone DC1468I Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Pargyline DCQ3Y8Y Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Idarubicin DC0DEAD Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Emetine + GSK2126458 DC2ATV7 GSK2126458 DD2 (Cell Line: DD2) [2]
Emetine + Probenecid DCCD5T7 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Darunavir DCVAEL8 Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Methylene blue DCU2TVP Methylene blue DD2 (Cell Line: DD2) [2]
Emetine + Clascoterone DC10YY2 Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Dopamine DCYBWSF Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Oxyphenbutazone DCWTO3H Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Acetohexamide DC3JF15 Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Leflunomide DCNKOBT Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Quinine DCRLJX1 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Quinine DCTQXJH Quinine DD2 (Cell Line: DD2) [2]
Emetine + Piperaquine DCP8ZZH Piperaquine DD2 (Cell Line: DD2) [2]
Emetine + Pomalidomide DCG98GD Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Endoxifen DCB86YX Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Mycophenolic acid DCNPNHB Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Bafilomycin A1 DCXBO4Z Bafilomycin A1 DD2 (Cell Line: DD2) [2]
Emetine + Pyronaridine DCUY36K Pyronaridine DD2 (Cell Line: DD2) [2]
Emetine + Lacosamide DCIXIGJ Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Iloprost DC1XZ4Z Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Zileuton DCFSQPW Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Nitisinone DC7671Z Nitisinone DD2 (Cell Line: DD2) [2]
Emetine + Sumatriptan DC5UFS3 Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + PMID28870136-Compound-43 DCPUPGT PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Estramustine DCJBA3N Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Cerivastatin DCVPYLG Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Metaxalone DC0LXR4 Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Busulfan DCZAOJ2 Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Atovaquone DCX08VG Atovaquone DD2 (Cell Line: DD2) [2]
Emetine + Aciclovir DCAHQW1 Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Enoxacin DCGIQ5C Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + GSK2194069 DC5MJ1O GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Cytarabine DCMRWBQ Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Emetine + Artemisinin DCOIXFZ Artemisinin Hepatoblastoma (Cell Line: HB3) [3]
Emetine + Quinine DCVCFTN Quinine Hepatoblastoma (Cell Line: HB3) [3]
Emetine + Piperaquine DCPJP2X Piperaquine Hepatoblastoma (Cell Line: HB3) [3]
Epinephrine + Emetine DCA522Q Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etonogestrel + Emetine DCZW408 Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ezetimibe + Emetine DC7KZYE Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fenoprofen + Emetine DCPC752 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GDC-0084 + Emetine DCP8565 GDC-0084 DD2 (Cell Line: DD2) [2]
GDC-0084 + Emetine DCWZILX GDC-0084 Hepatoblastoma (Cell Line: HB3) [3]
GS4071 + Emetine DCTL21K GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hyodeoxycholic acid + Emetine DC9UMA8 Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ibutilide + Emetine DC7XGLZ Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Emetine DC9C39J Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lumefantrine + Emetine DCWIPUD Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Emetine DCHAU8F Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylene blue + Emetine DCWYM82 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Emetine DC7WELZ Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + Emetine DCOPLRG Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nitisinone + Emetine DCX2ELU Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Olanzapine + Emetine DCRSROC Olanzapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + Emetine DCNBMVX Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + Emetine DC29TSQ Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pepstatin + Emetine DCHRJ62 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PFK-158 + Emetine DC2Y3TS PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pramipexole + Emetine DCPLACB Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Procarbazine + Emetine DCECIHU Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Repaglinide + Emetine DCMUW71 Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Rufinamide + Emetine DC8UQHN Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Spironolactone + Emetine DCH2DZY Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfinpyrazone + Emetine DCELZBV Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + Emetine DCF5URD Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tacrine + Emetine DCJMC4P Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terameprocol + Emetine DCJH0IX Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terazosin + Emetine DCME9NR Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone cypionate + Emetine DC355XC Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tolvaptan + Emetine DC9ZECU Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triamterene + Emetine DC9C6XI Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trifluoperazine + Emetine DCUCWV3 Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trihexyphenidyl + Emetine DCSWEM2 Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + Emetine DCIIPMW Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tropisetron + Emetine DCW0TWF Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vinblastine + Emetine DCU6PX0 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Emetine DCTJJSI Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
VR-776 + Emetine DCLTJMU VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
WAY-100635 + Emetine DC5SILO WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
------------------------------------------------------------------------------------
⏷ Show the Full List of 137 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.