General Information of This Drug (ID: DMPQAGE)

Drug Name
Mycophenolate mofetil   DMPQAGE
Synonyms
mycophenolate mofetil; 128794-94-5; CellCept; 115007-34-6; RS 61443; RS-61443; Munoloc; Mycophenolic acid morpholinoethyl ester; TM-MMF; Mycophenylate mofetil; Mycophenolatemofetil; UNII-9242ECW6R0; HSDB 7436; Cellcept (TN); 2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate; CHEBI:8764; C23H31NO7; Mycophenolate mofetil (CellCept); 9242ECW6R0; 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate; Myfenax; RS-61443-190; CellCept; MMF; CellCept (TN); ME-MPA; MMF CellCept(TM); R-99; Mycophenolate mofetil (JAN/USAN); CellCept, RS 61443, TM-MMF, Mycophenolate mofetil; 2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate; 2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate; 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate;4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
Indication
Disease Entry ICD 11 Status REF
Hepatosplenic T-cell lymphoma N.A. Approved [1]
Interstitial cystitis GC00.3 Approved [1]
Large granular lymphocytic leukemia 2A90.1 Approved [1]
Lupus nephritis 4A40.0Y Approved [1]
MALT lymphoma N.A. Approved [1]
Myeloid leukaemia 2B33.1 Approved [1]
Myeloproliferative neoplasm 2A20 Approved [1]
Nodal marginal zone lymphoma 2A85.0 Approved [1]
Organ transplant rejection NE84 Approved [2]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified N.A. Approved [1]
Recurrent adult burkitt lymphoma 2A85.6 Approved [1]
Small intestine lymphoma N.A. Approved [1]
Splenic marginal zone lymphoma N.A. Approved [1]
Systemic lupus erythematosus 4A40.0 Approved [1]
Testicular lymphoma N.A. Approved [1]
Pemphigus vulgaris EB40 Phase 3 [2]
Classic Hodgkin lymphoma N.A. Investigative [1]
Immune System disease 4A01-4B41 Investigative [3]
Middle East Respiratory Syndrome (MERS) 1D64 Investigative [4]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Immunosuppressive Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

68 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Clofarabine + Mycophenolate mofetil DCHJ30J Clofarabine Leukemia Lymphoblastic, Acute [5]
Cyclophosphamide + Mycophenolate mofetil DC3C2VJ Cyclophosphamide Acute Myeloid Leukemia (AML) [6]
Cyclophosphamide + Mycophenolate mofetil DCQ3HNZ Cyclophosphamide Systemic Scleroderma [7]
Cyclophosphamide + Mycophenolate mofetil DC65XI3 Cyclophosphamide Cutaneous T-Cell Non-Hodgkin Lymphoma [8]
Cyclophosphamide + Mycophenolate mofetil DC8O9B9 Cyclophosphamide Hodgkin's Lymphoma [9]
Cyclophosphamide + Mycophenolate mofetil DC8UWX2 Cyclophosphamide Acute Lymphoblastic Leukemia [10]
Cyclophosphamide + Mycophenolate mofetil DCDT6YJ Cyclophosphamide Graft Versus Host Disease [11]
Cyclophosphamide + Mycophenolate mofetil DCXVJKR Cyclophosphamide Accelerated Phase Chronic Myelogenous Leukemia [12]
Cyclophosphamide + Mycophenolate mofetil DCQAZQR Cyclophosphamide Hematologic Malignancies [13]
Cyclophosphamide + Mycophenolate mofetil DCQYR1O Cyclophosphamide Aplastic Anemia [14]
Methotrexate + Mycophenolate mofetil DC2P00C Methotrexate Acute Leukemia [15]
Mycophenolate mofetil + Prednisolone DC20QJN Prednisolone Lupus Nephritis [16]
Mycophenolate mofetil + Cyclosporin A DC6CQ1B Cyclosporin A Accelerated Phase Chronic Myelogenous Leukemia [17]
Mycophenolate mofetil + Cyclosporin A DCMN5XC Cyclosporin A Acute Myeloid Leukemia/Transient Myeloproliferative Disorder [18]
Mycophenolate mofetil + Prednisolone DCQ65OC Prednisolone Heart Transplantation [19]
Mycophenolate mofetil + Fludarabine DCS54G5 Fludarabine Systemic Scleroderma [7]
Mycophenolate mofetil + Cyclosporin A DC6PKR5 Cyclosporin A Kidney Dysfunction [20]
Mycophenolate mofetil + Tacrolimus DC7MMEK Tacrolimus Liver Dysfunction [21]
Mycophenolate mofetil + Tacrolimus DCMZP3N Tacrolimus Accelerated Phase Chronic Myelogenous Leukemia [22]
Mycophenolate mofetil + Prednisolone DCRH3VV Prednisolone Lupus Nephritis [23]
Mycophenolate mofetil + Cyclosporin A DCUQUC3 Cyclosporin A Adenosine Deaminase Deficiency [24]
Mycophenolate mofetil + Pantoprazole DCZS0WL Pantoprazole Transplantation [25]
Mycophenolate mofetil + Melphalan DC4ODJA Melphalan Refractory Multiple Myeloma [26]
Mycophenolate mofetil + Cyclosporin A DC1564L Cyclosporin A Adult Acute Myeloid Leukemia in Remission [27]
Mycophenolate mofetil + Mycophenolic acid DCGZFSP Mycophenolic acid Kidney Transplant [28]
Mycophenolate mofetil + Melphalan DCINNR2 Melphalan Refractory Multiple Myeloma [29]
Mycophenolate mofetil + Allopurinol DCJKVRN Allopurinol Small-cell Lung Cancer [30]
Mycophenolate mofetil + Cyclosporin A DCUTAIB Cyclosporin A Recurrent Renal Cell Cancer [31]
Mycophenolate mofetil + Sirolimus DC8HLX2 Sirolimus Adult Hodgkin Lymphoma [32]
Temozolomide + Mycophenolate mofetil DCR0EZW Temozolomide Recurrent Glioblastoma [33]
Clofarabine + Mycophenolate mofetil DC1GX0X Clofarabine Acute Myeloid Leukemia [34]
Cyclophosphamide + Mycophenolate mofetil DC9THKQ Cyclophosphamide Acute Myeloid Leukemia [35]
Cyclophosphamide + Mycophenolate mofetil DCB9RDM Cyclophosphamide Accelerated Phase Chronic Myelogenous Leukemia [36]
Cyclophosphamide + Mycophenolate mofetil DCUB5EU Cyclophosphamide Accelerated Phase Chronic Myelogenous Leukemia [37]
Cyclophosphamide + Mycophenolate mofetil DCV762J Cyclophosphamide Myelodysplastic Syndrome [38]
Cyclophosphamide + Mycophenolate mofetil DCZEYXM Cyclophosphamide Acute Myeloid Leukemia [39]
Cyclophosphamide + Mycophenolate mofetil DC9WCRN Cyclophosphamide Acute Leukemia [40]
Cyclophosphamide + Mycophenolate mofetil DCJP2JH Cyclophosphamide Hematologic Malignancy [41]
Cyclophosphamide + Mycophenolate mofetil DCKOQ5H Cyclophosphamide Hematological Malignancies [42]
Cyclophosphamide + Mycophenolate mofetil DCR907N Cyclophosphamide Hematopoietic and Lymphoid Cell Neoplasm [43]
Cyclophosphamide + Mycophenolate mofetil DC8LDFD Cyclophosphamide Hematopoietic/Lymphoid Cancer [44]
Everolimus + Mycophenolate mofetil DC6K1NQ Everolimus Delayed Graft Function [45]
Laquinimod + Mycophenolate mofetil DC5PFVE Laquinimod Lupus Nephritis [46]
Methimazole + Mycophenolate mofetil DCGOLRW Methimazole Graves' Disease [47]
Methotrexate + Mycophenolate mofetil DCX9VKT Methotrexate Chronic Myeloproliferative Disorders [48]
Mycophenolate mofetil + Cyclosporin A DCZHK3W Cyclosporin A Dyskeratosis Congenita [49]
Mycophenolate mofetil + Sirolimus DC2TH11 Sirolimus Acute Lymphoblastic Leukemia [50]
Mycophenolate mofetil + Cyclosporin A DCXMKNG Cyclosporin A Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities [51]
Mycophenolate mofetil + Methylprednisolone DCZDO0K Methylprednisolone Familial Lipoprotein Lipase Deficiency [52]
Mycophenolate mofetil + Voclosporin DC4ZMYY Voclosporin Systemic Lupus Erythematosus [53]
Mycophenolate mofetil + Bortezomib DC65YAN Bortezomib Lung Diseases, Interstitial [54]
Mycophenolate mofetil + Prednisolone DCIAZ0S Prednisolone Lupus Nephritis [55]
Mycophenolate mofetil + Methylprednisolone DCIZMOT Methylprednisolone Primary Renal Allograft Candidate [56]
Pentostatin + Mycophenolate mofetil DCFV0UE Pentostatin Acute Lymphoblastic Leukemia [57]
Methotrexate + Mycophenolate mofetil DCXC09Y Methotrexate Chronic Myelogenous Leukemia [58]
Mycophenolate mofetil + Methylprednisolone DCHYTTM Methylprednisolone Kidney Transplantation [59]
Mycophenolate mofetil + Methylprednisolone DC81D3X Methylprednisolone Systemic Lupus Erythematosus, Lupus Nephritis [60]
Budesonide + Mycophenolate mofetil DCWSC1S Budesonide Acute Cellular Graft Rejection [61]
Methotrexate + Mycophenolate mofetil DC3OAEB Methotrexate Hematopoietic Stem Cell Transplantation [62]
Methotrexate + Mycophenolate mofetil DC61B0K Methotrexate Beta-Thalassemia Major [63]
Mycophenolate mofetil + Azathioprine DCB31CC Azathioprine Carcinoma, Hepatocellular [64]
Mycophenolate mofetil + Methylprednisolone DCH7O7V Methylprednisolone Drug Interaction Potentiation [65]
Mycophenolate mofetil + Cyclosporin A DC66M1D Cyclosporin A Kidney Transplantation [66]
Mycophenolate mofetil + Methylprednisolone DC9852W Methylprednisolone Kidney Transplantation [67]
Mycophenolate mofetil + Methylprednisolone DC9C9H9 Methylprednisolone Renal Transplantation [68]
Mycophenolate mofetil + Cyclosporin A DCNKNWM Cyclosporin A Liver Transplantation [69]
Mycophenolate mofetil + Methylprednisolone DCOUY5O Methylprednisolone Liver Transplantation [70]
Thymalfasin + Mycophenolate mofetil DCLF0JG Thymalfasin IrAE [71]
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⏷ Show the Full List of 68 DrugCom(s)

References

1 Mycophenolate mofetil FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6831).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 341).
4 High-Throughput Screening and Identification of Potent Broad-Spectrum Inhibitors of Coronaviruses. J Virol. 2019 May 29;93(12). pii: e00023-19.
5 ClinicalTrials.gov (NCT01041508) Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.
6 ClinicalTrials.gov (NCT01962636) Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
7 ClinicalTrials.gov (NCT01047072) Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis
8 ClinicalTrials.gov (NCT02548468) Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma
9 ClinicalTrials.gov (NCT01342289) Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide
10 ClinicalTrials.gov (NCT00686556) Total Marrow Irradiation for Refractory Acute Leukemia
11 ClinicalTrials.gov (NCT00376519) Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases
12 ClinicalTrials.gov (NCT00343798) A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies
13 ClinicalTrials.gov (NCT00429143) A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative
14 ClinicalTrials.gov (NCT00354419) Cyclophosphamide, Antithymocyte Globulin, and Total-Body Irradiation in Treating Patients With Severe Aplastic Anemia Undergoing Umbilical Cord Blood Transplant
15 ClinicalTrials.gov (NCT02487069) Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy
16 ClinicalTrials.gov (NCT03791827) Multicenter Registry of Pediatric Lupus Nephritis in China
17 ClinicalTrials.gov (NCT00005799) Fludarabine Phosphate, Low-Dose Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer
18 ClinicalTrials.gov (NCT00014235) Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies
19 ClinicalTrials.gov (NCT00359658) Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation
20 ClinicalTrials.gov (NCT00420537) Shift to Everolimus (RAD) Kidney Sparing Study
21 ClinicalTrials.gov (NCT00117689) Evaluation of Thymoglobulin Induction and Reduced Doses of Calcineurin Inhibitors on Liver Transplant Rejection
22 ClinicalTrials.gov (NCT00089011) Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer
23 ClinicalTrials.gov (NCT00425438) A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.
24 ClinicalTrials.gov (NCT00008450) Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant
25 ClinicalTrials.gov (NCT01801280) Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS
26 ClinicalTrials.gov (NCT00054353) Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma
27 ClinicalTrials.gov (NCT00008177) Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes
28 ClinicalTrials.gov (NCT02711826) Treg Therapy in Subclinical Inflammation in Kidney Transplantation
29 ClinicalTrials.gov (NCT00003954) Melphalan and Stem Cell Transplant Before Total-Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma
30 ClinicalTrials.gov (NCT05049863) Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)
31 ClinicalTrials.gov (NCT00005851) Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Stage IV Kidney Cancer
32 ClinicalTrials.gov (NCT02728700) Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT
33 ClinicalTrials.gov (NCT04477200) Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma
34 ClinicalTrials.gov (NCT01252667) Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplant
35 ClinicalTrials.gov (NCT02566304) Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
36 ClinicalTrials.gov (NCT00049504) Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer
37 ClinicalTrials.gov (NCT01175785) Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies
38 ClinicalTrials.gov (NCT02556931) Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies
39 ClinicalTrials.gov (NCT00309842) Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
40 ClinicalTrials.gov (NCT02208037) Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)
41 ClinicalTrials.gov (NCT01341301) Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies
42 ClinicalTrials.gov (NCT01349101) A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors
43 ClinicalTrials.gov (NCT03032783) A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity
44 ClinicalTrials.gov (NCT01982682) Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor
45 ClinicalTrials.gov (NCT01878786) A Pilot Study Comparing the Safety and Efficacy of Everolimus With Other Medicines in Recipients of ECD/DCD Kidneys
46 ClinicalTrials.gov (NCT01085097) A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis
47 ClinicalTrials.gov (NCT06068179) Graves' Disease Remission Study: MycoMeth Combo
48 ClinicalTrials.gov (NCT00281879) Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
49 ClinicalTrials.gov (NCT01659606) Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
50 ClinicalTrials.gov (NCT03246906) Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation
51 ClinicalTrials.gov (NCT00040846) Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies
52 ClinicalTrials.gov (NCT00891306) Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects
53 ClinicalTrials.gov (NCT05306873) Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus
54 ClinicalTrials.gov (NCT02370693) Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis
55 ClinicalTrials.gov (NCT02949349) Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
56 ClinicalTrials.gov (NCT01856257) Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen
57 ClinicalTrials.gov (NCT00096161) Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant
58 ClinicalTrials.gov (NCT01951885) Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention
59 ClinicalTrials.gov (NCT00481819) A Study to Compare the Efficacy and Safety of FK506MR vs Prograf in Patients Undergoing Kidney Transplantation
60 ClinicalTrials.gov (NCT01773616) Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis
61 ClinicalTrials.gov (NCT03315052) Budesonide for Immunosuppression After Liver Transplantation to Reduce Side Effects
62 ClinicalTrials.gov (NCT04203108) ATG in HLA-matched Sibling HSCT as GVHD Prophylaxis
63 ClinicalTrials.gov (NCT02342145) Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major
64 ClinicalTrials.gov (NCT02081755) Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer
65 ClinicalTrials.gov (NCT02077556) Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients
66 ClinicalTrials.gov (NCT00087581) Study of Therapeutic Monitoring of Mycophenolate Mofetil (MMF/CellCept) After Kidney Transplantation
67 ClinicalTrials.gov (NCT00885820) Benefit of Early Protocol Biopsy and Treatment of Subclinical Rejection
68 ClinicalTrials.gov (NCT00650468) A Study to Compare Early Steroid Withdrawal and Long-Term Steroid Maintenance Therapy in Kidney Transplant Patients
69 ClinicalTrials.gov (NCT00118742) Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant
70 ClinicalTrials.gov (NCT00545402) A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.
71 ClinicalTrials.gov (NCT06178146) Thymosin Alpha-1 for irAE Secondary to ICIs