Details of the Drug Combinations

General Information of This Drug (ID: DMSWYF5)

Drug Name

Quinine DMSWYF5

Synonyms

Aflukin; Chinin; Chinine; Chininum; Conchinin; Conquinine; Quindan; Quinidex; Quinidine; Quinimax; Quinina; Quinineanhydrous; Quinora; Quniacridine; Chinin [German]; Kinder Quinina; QUININE MONO HCL; Quinine Dab; Quinine [BAN]; Quinine anhydrous; Quinine bisulfate; Quinine sulfate; Quinine sulphate; Quinoline alkaloid; LT00645788;Q0028; SB01652; Beta-Quinine; Cin-Quin; Coco-Quinine; IBS-L0034250; Kinder Quinina (TN); Legatrin (TN); Quinine (BAN); Quinine, Anhydrous; Quinine, polymers; Quinine, tannate; Biquinate (*Bisulfate heptathydrate*); Dentojel (*Bisulfate heptathydrate*); Quinamm (*2:1 Sulfate salt*), dihydrate; Quine (*2:1 Sulfate salt*, dihydrate); Quinsan (*2:1 Sulfate salt*), dihydrate; Alpha-(6-Methoxy-4-quinoyl)-5-vinyl-2-quinclidinemethanol; Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)-, sulfate; (+)-Quinidine; (-)-Quinine; (1R)-(6-Methoxyquinolin-4-yl)((1S,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (3A,8A,9r)-6'-methoxycinchonan-9-ol; (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (8-alpha,9R)-6'-Methoxycinchonan-9-ol; (8.alpha.,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-6'-Methoxycinchonan-9-ol; (8S,9R)-Quinine; (9R)-6'-methoxy-8alpha-cinchonan-9-ol; (R)-(-)-Quinine, 6-methoxycinchonidine; (R)-(-)-quinine; (R)-(6-Methoxy-quinolin-4-yl)-((2S,5S)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol; (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol; (R)-[(2S,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (R)-[(2S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; (S)-(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol; (S)-[(2R,4R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol; 6'-Methoxycinchonan-9-ol; 6'-Methoxycinchonidine; 6'-Methoxycinchonine; 6-Methoxycinchonine

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Approved	[1]
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Therapeutic Class

Antimalarials

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

164 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Alvespimycin hydrochloride + Quinine	DCAS3SW	Alvespimycin hydrochloride	DD2 (Cell Line: DD2)	[2]
Arfolitixorin + Quinine	DC8U28S	Arfolitixorin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Artemisinin + Quinine	DCV19DW	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Asenapine + Quinine	DCE84L4	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Auranofin + Quinine	DC4C6TZ	Auranofin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Azatadine + Quinine	DCONARY	Azatadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Baclofen + Quinine	DCYIGNV	Baclofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
BGT226 + Quinine	DC3X62K	BGT226	DD2 (Cell Line: DD2)	[2]
BGT226 + Quinine	DCJK4W7	BGT226	Hepatoblastoma (Cell Line: HB3)	[3]
Bifemelane + Quinine	DCLORM4	Bifemelane	DD2 (Cell Line: DD2)	[2]
Biperiden + Quinine	DCB5OQI	Biperiden	Hepatoblastoma (Cell Line: HB3)	[3]
Bortezomib + Quinine	DCYS183	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Carfilzomib + Quinine	DCUJ5G4	Carfilzomib	Hepatoblastoma (Cell Line: HB3)	[2]
Carglumic acid + Quinine	DC1C7ES	Carglumic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cefmenoxime + Quinine	DCTI27H	Cefmenoxime	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cisatracurium + Quinine	DCE9ZHC	Cisatracurium	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clopidogrel + Quinine	DCN290Z	Clopidogrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cycloguanil + Quinine	DCC9PRL	Cycloguanil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dichlorphenamide + Quinine	DCTAKNO	Dichlorphenamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dihydroergotamine + Quinine	DCF2GE1	Dihydroergotamine	DD2 (Cell Line: DD2)	[2]
Doxepin + Quinine	DC3ZGTP	Doxepin	DD2 (Cell Line: DD2)	[2]
Doxorubicin + Quinine	DCH819O	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Eflornithine + Quinine	DCO2UWP	Eflornithine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Emetine + Quinine	DCRLJX1	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Emetine + Quinine	DCTQXJH	Emetine	DD2 (Cell Line: DD2)	[2]
Emetine + Quinine	DCVCFTN	Emetine	Hepatoblastoma (Cell Line: HB3)	[3]
Ethinyl estradiol + Quinine	DCJCJEQ	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Everolimus + Quinine	DC3J6O1	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Fluspirilene + Quinine	DC7UADO	Fluspirilene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
FORMESTANE + Quinine	DCMT68V	FORMESTANE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Fosfomycin + Quinine	DC055AY	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Galantamine + Quinine	DCHY3WV	Galantamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GDC-0077 + Quinine	DCC8J31	GDC-0077	DD2 (Cell Line: DD2)	[2]
GDC-0084 + Quinine	DCUBHWP	GDC-0084	DD2 (Cell Line: DD2)	[2]
GDC-0084 + Quinine	DCVFRKE	GDC-0084	Hepatoblastoma (Cell Line: HB3)	[3]
Gentian violet + Quinine	DC8P21H	Gentian violet	Hepatoblastoma (Cell Line: HB3)	[3]
Ginsenoside Rb1 + Quinine	DC86QDJ	Ginsenoside Rb1	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GSK2126458 + Quinine	DC9LBBC	GSK2126458	DD2 (Cell Line: DD2)	[2]
GSK2126458 + Quinine	DCC0WVC	GSK2126458	Hepatoblastoma (Cell Line: HB3)	[3]
Ibutilide + Quinine	DCJZX0Y	Ibutilide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Idarubicin + Quinine	DCPXE67	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Itraconazole + Quinine	DCVT685	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
KN-62 + Quinine	DCKENE5	KN-62	Hepatoblastoma (Cell Line: HB3)	[3]
L-165041 + Quinine	DCPY6NZ	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Lacosamide + Quinine	DCWRD2D	Lacosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Lithium Citrate + Quinine	DCQY8OI	Lithium Citrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
LY03004 + Quinine	DC8YYS4	LY03004	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mesalazine + Quinine	DCVMOMC	Mesalazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Metaxalone + Quinine	DCKMIPD	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Metformin + Quinine	DC0ZHL4	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Methylene blue + Quinine	DC78TMV	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Methylergonovine + Quinine	DCP7PKD	Methylergonovine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Miconazole + Quinine	DCL4KK2	Miconazole	DD2 (Cell Line: DD2)	[2]
Miconazole + Quinine	DCWECGR	Miconazole	Hepatoblastoma (Cell Line: HB3)	[3]
Mycophenolic acid + Quinine	DCRWE88	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Naringenin + Quinine	DC3N7HG	Naringenin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Niclosamide + Quinine	DC98IRK	Niclosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Nizatidine + Quinine	DCOTFQX	Nizatidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Olanzapine + Quinine	DCZUE3C	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Omacetaxine mepesuccinate + Quinine	DC6PIJ7	Omacetaxine mepesuccinate	DD2 (Cell Line: DD2)	[2]
Oxandrolone + Quinine	DCL4UV5	Oxandrolone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pamidronate + Quinine	DCJ8X55	Pamidronate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Panobinostat + Quinine	DCBMZU3	Panobinostat	DD2 (Cell Line: DD2)	[2]
Panobinostat + Quinine	DC70906	Panobinostat	Hepatoblastoma (Cell Line: HB3)	[3]
Pazopanib + Quinine	DCJRFRI	Pazopanib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pepstatin + Quinine	DCX1A1D	Pepstatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Phensuximide + Quinine	DCHRLXQ	Phensuximide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pinacidil + Quinine	DCQI8CS	Pinacidil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PMID28460551-Compound-2 + Quinine	DC1V9OJ	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
PMID28870136-Compound-43 + Quinine	DCZFP23	PMID28870136-Compound-43	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pramipexole + Quinine	DCXPS2P	Pramipexole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pyrazinamide + Quinine	DC84ASJ	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Meclofenamic acid	DCQUSE7	Meclofenamic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Lefaxin	DCT3DI9	Lefaxin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Sertraline	DCMX47C	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Mebutamate	DC46F86	Mebutamate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Bepridil	DC0FHGU	Bepridil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Clindamycin	DCRBSE5	Clindamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Clindamycin	DC09ZY7	Clindamycin	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Paromomycin	DC0ZKPA	Paromomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Aliskiren	DC9TT2Q	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + OZ277	DCLN8X2	OZ277	DD2 (Cell Line: DD2)	[2]
Quinine + OZ277	DCZQEK6	OZ277	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Lumefantrine	DC26EUD	Lumefantrine	DD2 (Cell Line: DD2)	[2]
Quinine + Lumefantrine	DCQOVQW	Lumefantrine	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Kanamycin	DCQFO0I	Kanamycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Citalopram	DCGIX91	Citalopram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Crotamiton	DCAPLCY	Crotamiton	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Dactinomycin	DCJMGLO	Dactinomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Artemether	DC3OBBQ	Artemether	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Trioxsalen	DCYLW3U	Trioxsalen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Sivelestat	DCK2ID7	Sivelestat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Testosterone	DCSQ1N8	Testosterone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Triapine	DCL5ZQI	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Dexmedetomidine	DCU4J0Z	Dexmedetomidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + 10-hydroxycamptothecin	DC2K90I	10-hydroxycamptothecin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Rifampin	DCPVT3K	Rifampin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + IT-141	DCWUATR	IT-141	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Palonosetron	DCR52N8	Palonosetron	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + BHV-0223	DCIHUHB	BHV-0223	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Terameprocol	DCDC9ZH	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Doxapram	DCF4SOS	Doxapram	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + K-134	DCJ4SF5	K-134	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + JZL195	DCEPCPT	JZL195	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + WAY-100635	DCTLHAN	WAY-100635	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Armodafinil	DC1CCYV	Armodafinil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Sitagliptin	DC4A9NU	Sitagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Pentamidine	DC6CU7A	Pentamidine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Procarbazine	DC5HQ9Q	Procarbazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Bosentan	DCA1VMD	Bosentan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + BIO-300	DC7MPZV	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Lubiprostone	DCKD9S1	Lubiprostone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Idarubicin	DCSZBO4	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
Quinine + Epothilone B	DC6TFIL	Epothilone B	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Methylene blue	DCAQRHN	Methylene blue	DD2 (Cell Line: DD2)	[2]
Quinine + Methylene blue	DCT7HPY	Methylene blue	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Acamprosate	DCI23SA	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Artemisinin	DCT2NZS	Artemisinin	DD2 (Cell Line: DD2)	[2]
Quinine + Artemisinin	DC32HDT	Artemisinin	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Maprotiline	DC1CJA0	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Acetohexamide	DC5Y38F	Acetohexamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Ethambutol	DCZ0ZBL	Ethambutol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Amantadine	DCXRX2F	Amantadine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Clomiphene citrate	DCTDO50	Clomiphene citrate	DD2 (Cell Line: DD2)	[2]
Quinine + Chloroquine	DCNYA6J	Chloroquine	DD2 (Cell Line: DD2)	[2]
Quinine + Hyodeoxycholic acid	DCX22MG	Hyodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Piperaquine	DCHU3L6	Piperaquine	DD2 (Cell Line: DD2)	[2]
Quinine + MK-4815	DCBS0NK	MK-4815	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Pomalidomide	DCRHZR8	Pomalidomide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Hydralazine	DCR0IFL	Hydralazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Mefloquine	DCLORWH	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Mefloquine	DCFIEDB	Mefloquine	DD2 (Cell Line: DD2)	[2]
Quinine + Mefloquine	DCKQH8W	Mefloquine	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Pizotyline	DCRFC2A	Pizotyline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Rufinamide	DCRDO7F	Rufinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Vorinostat	DCG35G3	Vorinostat	Hepatoblastoma (Cell Line: HB3)	[2]
Quinine + Busulfan	DCN7T40	Busulfan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Aciclovir	DCR4TPP	Aciclovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + Acetohydroxamic Acid	DCAO1C7	Acetohydroxamic Acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + AS-1949490	DC72IK3	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Quinine + GSK2194069	DCF33E3	GSK2194069	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Repaglinide + Quinine	DCRJFRP	Repaglinide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sapanisertib + Quinine	DCP684M	Sapanisertib	DD2 (Cell Line: DD2)	[2]
Sarpogrelate + Quinine	DCHC8C5	Sarpogrelate	Hepatoblastoma (Cell Line: HB3)	[3]
SB 228357 + Quinine	DCMD9YY	SB 228357	DD2 (Cell Line: DD2)	[2]
Silver sulfadiazine + Quinine	DCG63SL	Silver sulfadiazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sumatriptan + Quinine	DCLSMFV	Sumatriptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Tacrolimus + Quinine	DCO6VHS	Tacrolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Testolactone + Quinine	DCT12F7	Testolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
TG100-115 + Quinine	DCQPNO5	TG100-115	DD2 (Cell Line: DD2)	[2]
TG100-115 + Quinine	DCO4AT1	TG100-115	Hepatoblastoma (Cell Line: HB3)	[2]
Torin 1 + Quinine	DCP2ZLW	Torin 1	DD2 (Cell Line: DD2)	[2]
Tranylcypromine + Quinine	DCUY14O	Tranylcypromine	Hepatoblastoma (Cell Line: HB3)	[2]
Trichostatin A + Quinine	DCT3KT3	Trichostatin A	DD2 (Cell Line: DD2)	[2]
Trichostatin A + Quinine	DCZ6KG6	Trichostatin A	Hepatoblastoma (Cell Line: HB3)	[3]
Triiodothyronine + Quinine	DC87Y11	Triiodothyronine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Trimethobenzamide + Quinine	DCMW4PN	Trimethobenzamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ursodeoxycholic acid + Quinine	DCIE3ZE	Ursodeoxycholic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Valproic Acid + Quinine	DC7HICM	Valproic Acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Vinblastine + Quinine	DCD1FRM	Vinblastine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Vorinostat + Quinine	DCUFWGL	Vorinostat	DD2 (Cell Line: DD2)	[2]
Vorinostat + Quinine	DCLZHNN	Vorinostat	Hepatoblastoma (Cell Line: HB3)	[2]
ZSTK474 + Quinine	DC28M9K	ZSTK474	DD2 (Cell Line: DD2)	[2]
ZSTK474 + Quinine	DC892SW	ZSTK474	Hepatoblastoma (Cell Line: HB3)	[2]
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⏷ Show the Full List of 164 DrugCom(s)

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Theophylline + Quinine	DC45DY7	Theophylline	Pharmacokinetics	[4]
Artesunate + Quinine	DCQ24P0	Artesunate	Malaria	[5]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2510).
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3	Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
4	ClinicalTrials.gov (NCT00779259) Drug - Drug Interaction Study Between Quinine Sulfate and Theophylline
5	ClinicalTrials.gov (NCT01805232) Intravenous Artesunate and Malaria