Details of the Drug Combinations

General Information of This Drug (ID: DMZA017)

Drug Name
Tetracycline   DMZA017
Synonyms
Amycin; Biocycline; Bristaciclin; Bristaciclina; Bristacycline; Ciclibion; Copharlan; Cyclomycin; Cytome; Dumocyclin; Enterocycline; Medocycline; Resteclin; Robitet; Sanclomycine; Tetrachel; Veracin; Bristaciclin alpha; Cefracycline suspension; Component of Tetrastatin; Sumycin syrup; Tetracycline Free Base; Tetracycline I; Tetracycline II; Tetracycline Monohydrochloride; Achromycin (naphthacene derivative); Achromycin, naphthacene derivative; Centet (base); Lemtrex (base); Liquamycin (Veterinary); Liquamycin, veterinary; Panmycin (TN); Piracaps (base); Polycycline (VAN); Polycycline (antibiotic); Polycycline, antibiotic; SK-Tetracycline; Sumycin (TN); T-125; Tetra-Co; Tetraciclina [INN-Spanish]; Tetracycline & VRC3375; Tetracycline (internal use); Tetracyclinum [INN-Latin]; Tetracyn (TN); Vetquamycin-324 (free base); Tetracycline (JAN/USP/INN); Tetracycline [USAN:INN:BAN:JAN]; Methyl-1,11-dioxo-2-naphthacenecarboxamide; 6-Methyl-1,11-dioxy-2-naphthacenecarboxamide
Indication
Disease Entry ICD 11 Status REF
Acne vulgaris ED80 Approved [1]
Actinomycosis N.A. Approved [1]
Acute gonococcal cervicitis N.A. Approved [1]
Acute gonococcal epididymo-orchitis N.A. Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Bronchitis CA20 Approved [1]
Brucellosis N.A. Approved [1]
Lymphogranuloma venereum N.A. Approved [1]
Ornithosis N.A. Approved [1]
Pneumonia CA40 Approved [1]
Q fever N.A. Approved [1]
Relapsing fever N.A. Approved [1]
Rickettsialpox N.A. Approved [1]
Rocky mountain spotted fever N.A. Approved [1]
Syphilis N.A. Approved [1]
Trachoma N.A. Approved [1]
Typhus N.A. Approved [1]
Urinary tract infection GC08 Approved [1]
Yaws N.A. Approved [1]
Pelvic inflammatory disease GA05 Investigative [1]
Sinusitis CA0A.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

54 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Aciclovir + Tetracycline DC0GIZ0 Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Auranofin + Tetracycline DC3JYPC Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Tetracycline DCIKPFB Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BRL-15572 + Tetracycline DCXDNR7 BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cilostazol + Tetracycline DC4F5LE Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dichlorphenamide + Tetracycline DCQQNP4 Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diethylcarbamazine + Tetracycline DCT3GMI Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Eflornithine + Tetracycline DCNXII6 Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Entacapone + Tetracycline DCDG7G7 Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Tetracycline DCX1IDM Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Galantamine + Tetracycline DCXENFQ Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
GS4071 + Tetracycline DCDT8J0 GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Idarubicin + Tetracycline DCUB63Y Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imatinib + Tetracycline DCH8MID Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
K-134 + Tetracycline DCUF24Y K-134 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Kanamycin + Tetracycline DC0Q7VJ Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebutamate + Tetracycline DCK289W Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Tetracycline DCPULF5 Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Tetracycline DCFD01B Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Tetracycline DCL5AH9 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oxandrolone + Tetracycline DCYJB7Q Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Phenprocoumon + Tetracycline DC6ZCCY Phenprocoumon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pinacidil + Tetracycline DC4QG5J Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28460551-Compound-2 + Tetracycline DCV09VQ PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Probenecid + Tetracycline DCGSIQ6 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pyrazinamide + Tetracycline DCY7H4N Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Raltegravir + Tetracycline DCIKBTO Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sivelestat + Tetracycline DCCLZHA Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Sumatriptan + Tetracycline DC0EKW6 Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Teriflunomide + Tetracycline DC0UV24 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Aprepitant DCP3HOI Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Aliskiren DCQJ0NN Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Citalopram DC1F4E8 Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Miglustat DCMRYIR Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Terameprocol DCSY88G Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Chlorzoxazone DCEB31F Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + BIO-300 DCHT0SM BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Isoproterenol DCZ03MW Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Benserazide DCV75R9 Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Bortezomib DCNE1U0 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Methylene blue DC19ZUE Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Leflunomide DCUHIKQ Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Brincidofovir DCZYRS8 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Mycophenolic acid DCH68S0 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Doxorubicin DCCAJNU Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Olmesartan medoxomil DC0V0TC Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Vorinostat DCS8494 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tetracycline + Estramustine DCQ0Z4Z Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tiagabine + Tetracycline DC7LGD1 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trifluoperazine + Tetracycline DCAWMT1 Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Tetracycline DC17XBT Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Tetracycline DC55SHJ Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Tetracycline DCL14D5 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Zaleplon + Tetracycline DC8QIF7 Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 54 DrugCom(s)
2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Azithromycin + Tetracycline DCIYFBD Azithromycin Trachoma [4]
Amoxicillin + Tetracycline DC66HUF Amoxicillin Antimicrobial Susceptibility Testing [5]
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References

1 Tetracycline FDA Label
2 How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT02754583) Sanitation, Water, and Instruction in Face-washing for Trachoma I/II
5 ClinicalTrials.gov (NCT03139253) Antimicrobial Susceptibility Testing Guided Triple Therapy in Salvage Helicobacter Pylori Treatment