General Information of Drug (ID: DM3MJUS)

Drug Name
NBTX-001 Drug Info
Indication
Disease Entry ICD 11 Status REF
Post-traumatic stress disorder 6B40 Phase 2/3 [1]
Panic disorder 6B01 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DM3MJUS

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [3]
Cycloserine DMT1I52 Bacterial infection 1A00-1C4Z Approved [4]
Benzphetamine DMIJATC Obesity 5B81 Approved [5]
Ketamine DMT5HA4 Anaesthesia 9A78.6 Approved [6]
Felbamate DM1V5ZS Epilepsy 8A60-8A68 Approved [7]
Memantine DMD9WSC Alzheimer disease 8A20 Approved [8]
Huperzine A DMMAWLU Alzheimer disease 8A20 Approved [9]
Levorphanol DMGS80V Pain MG30-MG3Z Approved [10]
Magnesium Sulfate DMVEK07 Acute pain MG31 Approved [11]
Magnesium DMU4ORS Ischemic stroke 8B11.5Z Approved [12]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
N-methyl-D-aspartate receptor (NMDAR) TT9IK2Z NOUNIPROTAC Antagonist [2]

References

1 ClinicalTrials.gov (NCT03635827) Xenon Inhalation for Treatment of Posttraumatic Stress Disorder. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia pati... Am J Psychiatry. 2008 Dec;165(12):1594-603.
4 How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73.
5 Amphetamine inhibits the N-methyl-D-aspartate receptor-mediated responses by directly interacting with the receptor/channel complex. J Pharmacol Exp Ther. 2002 Mar;300(3):1008-16.
6 Ketamine modulates theta and gamma oscillations. J Cogn Neurosci. 2010 Jul;22(7):1452-64.
7 Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor. J Med Chem. 2008 Mar 27;51(6):1534-45.
8 The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence. Int J Geriatr Psychiatry. 2003 Sep;18(Suppl 1):S23-32.
9 Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43.
10 Neuroprotective agents for the treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 2003 Jan;3(1):9-20.
11 Magnesium sulfate diminishes the effects of amide local anesthetics in rat sciatic-nerve block. Reg Anesth Pain Med. 2007 Jul-Aug;32(4):288-95.
12 Emerging drugs for acute ischemic stroke. Expert Opin Emerg Drugs. 2009 Mar;14(1):33-42.