General Information of Drug (ID: DMNKT8Z)

Drug Name
Pachycarpine Drug Info
Synonyms (+)-sparteine
Indication
Disease Entry ICD 11 Status REF
Postpartum haemorrhage JA43 Approved [1]
Cross-matching ID
PubChem CID
7014
CAS Number
CAS 492-08-0
TTD Drug ID
DMNKT8Z

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [3]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [4]
Zonisamide DM0DTF7 Alcohol dependence 6C40.2 Approved [5]
Eslicarbazepine DMZREFQ Seizure disorder 8A6Z Approved [6]
LIDOFLAZINE DMV23GL Angina pectoris BA40 Approved [7]
LOMERIZINE DME0TC8 Migraine 8A80 Approved [8]
Levobupivacaine DM783CH Anaesthesia 9A78.6 Approved [9]
Tetrodotoxin DMWMPRG Bacterial infection 1A00-1C4Z Approved [10]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [11]
Rufinamide DMWE60C Epilepsy 8A60-8A68 Approved [12]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sodium channel unspecific (NaC) TTRK8B9 NOUNIPROTAC Modulator [2]

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Medicinal plants in therapy. Bull World Health Organ. 1985;63(6):965-81.
3 Lacosamide: a new approach to target voltage-gated sodium currents in epileptic disorders. CNS Drugs. 2009;23(7):555-68.
4 Sidedness of carbamazepine accessibility to voltage-gated sodium channels. Mol Pharmacol. 2014 Feb;85(2):381-7.
5 Antiepileptic drugs and relapse after epilepsy surgery. Epileptic Disord. 2008 Sep;10(3):193-8.
6 Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43.
7 Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers. J Med Chem. 1994 Jan 21;37(2):268-74.
8 Medicinal chemistry of neuronal voltage-gated sodium channel blockers. J Med Chem. 2001 Jan 18;44(2):115-37.
9 Block of neuronal tetrodotoxin-resistant Na+ currents by stereoisomers of piperidine local anesthetics. Anesth Analg. 2000 Dec;91(6):1499-505.
10 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
11 In vitro assays for repellents and deterrents for ticks: differing effects of products when tested with attractant or arrestment stimuli. Med Vet Entomol. 2003 Dec;17(4):370-8.
12 Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.