Details of the Drug

General Information of Drug (ID: DMXK8FQ)

Drug Name

VP004

Indication

Disease Entry	ICD 11	Status	REF
Substance use disorder	6C4Z	Discontinued in Phase 1	[1]
------------------------------------------------------------------------------------

Drug Type

Antibody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Opioid receptor delta (OPRD1)	TT27RFC	OPRD_HUMAN	Not Available	[2]
Opioid receptor kappa (OPRK1)	TTQW87Y	OPRK_HUMAN	Not Available	[2]
Opioid receptor mu (MOP)	TTKWM86	OPRM_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Substance use disorder

ICD Disease Classification

6C4Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Opioid receptor mu (MOP)	DTT	OPRM1	5.94E-01	-0.02	-0.17
Opioid receptor delta (OPRD1)	DTT	OPRD1	5.52E-01	0.03	0.23

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025668)
2	WO patent application no. 2007,0677,14, Treatment of sequelae of psychiatric disorders.