Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TT5HONZ)

• DTT Name: Calcium channel unspecific (CaC) DTT Info
• Gene Name: CaC

Molecule-Related Drug & Molecule List

7 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[1]
Clevidipine butyrate	DMW4M97	Hypertension	BA00-BA04	Approved	[2]
Felodipine	DMOSW35	Hypertension	BA00-BA04	Approved	[3]
Isradipine	DMA5XGH	Hypertension	BA00-BA04	Approved	[1]
Nicardipine	DMCDYW7	High blood pressure	BA00	Approved	[4]
Nimodipine	DMQ0RKZ	Cerebral vasospasm	BA85.Z	Approved	[5]
Nisoldipine	DM7ISKJ	Hypertension	BA00-BA04	Approved	[6]

11 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DIPROTEVERINE HYDROCHLORIDE	DMG8U6M	Angina pectoris	BA40	Phase 3	[7]
Arverapamil	DML27AE	Irritable bowel syndrome	DD91.0	Phase 2	[8]
ATI-2042	DMWP59B	Atrial fibrillation	BC81.3	Phase 2	[9]
HBI-3000	DM74ZKN	Heart arrhythmia	BC65	Phase 2	[10]
Nexopamil	DML5S71	Hypertension	BA00-BA04	Phase 2	[11]
S-2150	DMTAX8B	Angina pectoris	BA40	Phase 2	[12]
CM2489	DMMC6YR	Psoriasis vulgaris	EA90	Phase 1	[13]
DSP-0565	DMY95MZ	Epilepsy	8A60-8A68	Phase 1	[14]
Elpetrigine	DMIV04R	Bipolar disorder	6A60	Phase 1	[15]
Tetrandrine	DMAOJBX	Sarcoma	2A60-2C35	Phase 1	[16]
YM-16151-4	DMNLY9R	Hypertension	BA00-BA04	Phase 1	[17]

53 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AE-0047	DMTF9YV	Hypertension	BA00-BA04	Discontinued in Preregistration	[18]
Monatepil maleate	DM9ADLQ	Angina pectoris	BA40	Discontinued in Preregistration	[19]
Palonidipine hydrochloride	DMUH0KO	Hypertension	BA00-BA04	Discontinued in Preregistration	[20]
Semotiadil	DMYBPJ1	Hypertension	BA00-BA04	Discontinued in Preregistration	[21]
Anipamil	DMNEM2C	Hypertension	BA00-BA04	Discontinued in Phase 3	[22]
ELGODIPINE HYDROCHLORIDE	DMJOM31	Angina pectoris	BA40	Discontinued in Phase 3	[23]
S-12968	DMPUED3	Hypertension	BA00-BA04	Discontinued in Phase 3	[24]
AM336	DMF8KH7	Pain	MG30-MG3Z	Discontinued in Phase 2	[25]
BRL-32872A	DMRKBIU	Cardiac arrhythmias	BC9Z	Discontinued in Phase 2	[26]
CD-349	DM9P7Z2	Hypertension	BA00-BA04	Discontinued in Phase 2	[27]
Dopropidil	DMMC6H7	Angina pectoris	BA40	Discontinued in Phase 2	[28]
FLOSATIDIL	DMOCMXH	Angina pectoris	BA40	Discontinued in Phase 2	[29]
Levosemotiadil	DMKSY2R	Cardiac arrhythmias	BC9Z	Discontinued in Phase 2	[30]
Lifarizine	DM3R8TI	Nerve injury	ND56.4	Discontinued in Phase 2	[31]
S-312-d	DMQ2RDZ	Epilepsy	8A60-8A68	Discontinued in Phase 2	[32]
TAMOLARIZINE HYDROCHLORIDE	DM1L5UX	Cognitive impairment	6D71	Discontinued in Phase 2	[33]
CEREBROCRAST	DMK93VQ	Nerve injury	ND56.4	Discontinued in Phase 1	[34]
CERM-11956	DMQKRWO	Angina pectoris	BA40	Discontinued in Phase 1	[35]
IGANIDIPINE HYDROCHLORIDE	DMP8MBW	Glaucoma/ocular hypertension	9C61	Discontinued in Phase 1	[36]
KT-362	DM74BK8	Heart arrhythmia	BC65	Discontinued in Phase 1	[37]
NP-252	DMT8IGE	Hypertension	BA00-BA04	Discontinued in Phase 1	[38]
SM-6586	DM6CLX9	Hypertension	BA00-BA04	Discontinued in Phase 1	[39]
SR-33805	DM471IG	Angina pectoris	BA40	Discontinued in Phase 1	[40]
AHR-16303B	DMJZ48W	Hypertension	BA00-BA04	Terminated	[42]
AHR-16462B	DMJ6BEO	Hypertension	BA00-BA04	Terminated	[43]
AJ-3941	DMOJTZV	Cerebrovascular ischaemia	8B1Z	Terminated	[44]
CD-832	DM5FEBQ	Angina pectoris	BA40	Terminated	[45]
Clentiazem	DM8TQC9	Angina pectoris	BA40	Terminated	[46]
Darodipine	DM160FM	Cerebrovascular ischaemia	8B1Z	Terminated	[47]
DHP-218	DM5VFR0	Hypertension	BA00-BA04	Terminated	[48]
E-2050	DMQKEHA	Cerebrovascular ischaemia	8B1Z	Terminated	[49]
Emopamil	DMW210B	Cerebrovascular ischaemia	8B1Z	Terminated	[50]
LAS-30538	DM07S4N	Hyperinsulinemia	5A4Y	Terminated	[51]
Naltiazem hydrochloride	DM7T2FO	Angina pectoris	BA40	Terminated	[52]
NNC-09-0026	DMGEHZ9	Cerebrovascular ischaemia	8B1Z	Terminated	[53]
NS-638	DMPT74G	Cerebrovascular ischaemia	8B1Z	Terminated	[54]
NS-649	DMXKMRV	Alzheimer disease	8A20	Terminated	[55]
NS-696	DMI46T3	Epilepsy	8A60-8A68	Terminated	[56]
Pranidipine	DMI2N9H	Angina pectoris	BA40	Terminated	[57]
RS-93522	DMZHS9U	Hypertension	BA00-BA04	Terminated	[58]
RWJ-22108	DMBXDQG	Allergy	4A80-4A85	Terminated	[59]
RWJ-37868	DM17WNG	Epilepsy	8A60-8A68	Terminated	[60]
SB-206284A	DM5ZPQJ	Cerebrovascular ischaemia	8B1Z	Terminated	[61]
SB-237376	DMBCANZ	Arrhythmia	BC9Z	Terminated	[62]
SDZ-249482	DMPZLKC	Pain	MG30-MG3Z	Terminated	[63]
SIM-6080	DMBZ7SF	Angina pectoris	BA40	Terminated	[64]
Siratiazem	DMG90YW	Angina pectoris	BA40	Terminated	[65]
SKF-96365	DMI79JN	Angina pectoris	BA40	Terminated	[66]
SQ-33351	DM083JB	Hypertension	BA00-BA04	Terminated	[67]
UK-51656	DM23YPS	Cardiovascular disease	BA00-BE2Z	Terminated	[68]
VUF-8929	DM0CWJZ	Heart failure	BD10-BD13	Terminated	[69]
Z-6568	DMQ6K8J	Hypertension	BA00-BA04	Terminated	[70]
ZM-224832	DM8V0YA	Hypertension	BA00-BA04	Terminated	[71]

1 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Rycals	DMXM2BZ	Heart failure	BD10-BD13	Preclinical	[41]

6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AGN-190744	DMIKDAR	Discovery agent	N.A.	Investigative	[72]
BELFOSDIL	DM0WOS6	Discovery agent	N.A.	Investigative	[73]
CD-832.HCL	DMFYWE3	Discovery agent	N.A.	Investigative	[74]
leualacin	DMV40XH	Discovery agent	N.A.	Investigative	[75]
SR-33805A	DMPO4WX	Hypertension	BA00-BA04	Investigative	[76]
TELUDIPINE HYDROCHLORIDE	DMT4NWX	Hypertension	BA00-BA04	Investigative	[77]

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