Details of the Drug Combination

General Information of Drug Combination (ID: DC61NWM)

• Drug Combination Name: Letrozole + Zoledronate
• Indication: Breast Neoplasms; Status: Phase 1 [1]
• Component Drugs:
  Letrozole (DMH07Y3): Small molecular drug
  Zoledronate (DMIXC7G): Small molecular drug

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Letrozole

Disease Entry	ICD 11	Status	REF
Estrogen-receptor positive breast cancer	N.A.	Approved	[2]
Hormonally-responsive breast cancer	2C60-2C65	Approved	[3]

Letrozole Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Aromatase (CYP19A1)	TTSZLWK	CP19A_HUMAN	Inhibitor	[10]

Letrozole Interacts with 3 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[11]
Aromatase (CYP19A1)	DEQX145	CP19A_HUMAN	Metabolism	[12]
Cytochrome P450 2A6 (CYP2A6)	DEJVYAZ	CP2A6_HUMAN	Metabolism	[13]

Letrozole Interacts with 18 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Aromatase (CYP19A1)	OTZ6XF74	CP19A_HUMAN	Decreases Activity	[14]
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Increases Oxidation	[15]
Cytochrome P450 2A6 (CYP2A6)	OT52TWG3	CP2A6_HUMAN	Increases Oxidation	[15]
Adenylate kinase isoenzyme 1 (AK1)	OT614AR3	KAD1_HUMAN	Increases ADR	[16]
Dickkopf-related protein 1 (DKK1)	OTRDLUSP	DKK1_HUMAN	Increases Expression	[17]
Follitropin subunit beta (FSHB)	OTGLS283	FSHB_HUMAN	Increases Expression	[18]
Lutropin subunit beta (LHB)	OT5GBOVJ	LSHB_HUMAN	Increases Expression	[18]
Progesterone receptor (PGR)	OT0FZ3QE	PRGR_HUMAN	Decreases Expression	[19]
Leukemia inhibitory factor (LIF)	OTO46S5S	LIF_HUMAN	Increases Expression	[17]
Gap junction alpha-1 protein (GJA1)	OTT94MKL	CXA1_HUMAN	Decreases Expression	[20]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Decreases Expression	[21]
G1/S-specific cyclin-D2 (CCND2)	OTDULQF9	CCND2_HUMAN	Decreases Expression	[21]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[22]
Leukemia inhibitory factor receptor (LIFR)	OT36W9O5	LIFR_HUMAN	Increases Expression	[17]
Proliferation marker protein Ki-67 (MKI67)	OTA8N1QI	KI67_HUMAN	Decreases Expression	[19]
Small ribosomal subunit protein eS6 (RPS6)	OTT4D1LN	RS6_HUMAN	Decreases Phosphorylation	[21]
Lanosterol 14-alpha demethylase (CYP51A1)	OTAYHG9C	CP51A_HUMAN	Decreases Activity	[23]
Fibroblast growth factor 22 (FGF22)	OTVIX6J0	FGF22_HUMAN	Increases Expression	[17]

Indication(s) of Zoledronate

Disease Entry	ICD 11	Status	REF
Adenocarcinoma	2D40	Approved	[4]
Bone giant cell tumor	N.A.	Approved	[5]
Bone Paget disease	N.A.	Approved	[6]
Hypercalcaemia	5B91.0	Approved	[7]
Multiple sclerosis	8A40	Approved	[8]
Osteoporosis	FB83.0	Approved	[9]

Zoledronate Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Geranyltranstransferase (FDPS)	TTIKWV4	FPPS_HUMAN	Modulator	[30]

Zoledronate Interacts with 1 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[31]

Zoledronate Interacts with 1372 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Protein TESPA1 (TESPA1)	OTEGT4GI	TESP1_HUMAN	Decreases Expression	[24]
DNA fragmentation factor subunit alpha (DFFA)	OTFPFMT8	DFFA_HUMAN	Decreases Expression	[24]
Basic helix-loop-helix ARNT-like protein 1 (BMAL1)	OTMI12L2	BMAL1_HUMAN	Increases Expression	[24]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A)	OTFBU4GD	P3C2A_HUMAN	Increases Expression	[24]
Exocyst complex component 5 (EXOC5)	OT9S9NJ7	EXOC5_HUMAN	Increases Expression	[24]
RNA polymerase II elongation factor ELL2 (ELL2)	OTZJRTFM	ELL2_HUMAN	Increases Expression	[24]
Nuclear envelope integral membrane protein 1 (NEMP1)	OTWN3S47	NEMP1_HUMAN	Increases Expression	[24]
Syntaxin-16 (STX16)	OTM7TAOE	STX16_HUMAN	Increases Expression	[24]
Krueppel-like factor 11 (KLF11)	OTKVQDJD	KLF11_HUMAN	Increases Expression	[24]
Histone-lysine N-methyltransferase SETD1A (SETD1A)	OTVVWRIC	SET1A_HUMAN	Decreases Expression	[24]
Protein Mdm4 (MDM4)	OTU10BSF	MDM4_HUMAN	Increases Expression	[24]
NF-kappa-B-repressing factor (NKRF)	OTUVY0P6	NKRF_HUMAN	Decreases Expression	[24]
DNA-directed RNA polymerase II subunit RPB4 (POLR2D)	OTW7RZ18	RPB4_HUMAN	Increases Expression	[24]
Claudin-3 (CLDN3)	OT71MN9S	CLD3_HUMAN	Increases Expression	[24]
Synaptojanin-1 (SYNJ1)	OTTE02XC	SYNJ1_HUMAN	Increases Expression	[24]
Membrane-bound transcription factor site-2 protease (MBTPS2)	OT67CC7W	MBTP2_HUMAN	Increases Expression	[24]
Regulator of G-protein signaling 14 (RGS14)	OTYN79AG	RGS14_HUMAN	Increases Expression	[24]
Copine-3 (CPNE3)	OTCR3WG2	CPNE3_HUMAN	Increases Expression	[24]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Increases Expression	[24]
Mannose-P-dolichol utilization defect 1 protein (MPDU1)	OT27UPHN	MPU1_HUMAN	Increases Expression	[24]
Erlin-1 (ERLIN1)	OTUOOODY	ERLN1_HUMAN	Increases Expression	[24]
DNA repair protein RAD51 homolog 4 (RAD51D)	OTKOU5XN	RA51D_HUMAN	Increases Expression	[24]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)	OTYG179K	PR15A_HUMAN	Increases Expression	[24]
Krueppel-like factor 7 (KLF7)	OTS3YVA0	KLF7_HUMAN	Increases Expression	[24]
Serine hydrolase RBBP9 (RBBP9)	OT0Z04L6	RBBP9_HUMAN	Increases Expression	[24]
Carboxypeptidase D (CPD)	OT2CS64Y	CBPD_HUMAN	Increases Expression	[24]
Glutaredoxin-3 (GLRX3)	OTUPAU1N	GLRX3_HUMAN	Decreases Expression	[24]
TOX high mobility group box family member 4 (TOX4)	OTSOXQFN	TOX4_HUMAN	Increases Expression	[24]
Adhesion G protein-coupled receptor L1 (ADGRL1)	OT6O9T1Q	AGRL1_HUMAN	Decreases Expression	[24]
Kinesin-like protein KIF20A (KIF20A)	OTXOQHE0	KI20A_HUMAN	Decreases Expression	[24]
Amyloid-beta A4 precursor protein-binding family A member 3 (APBA3)	OTAAATXF	APBA3_HUMAN	Decreases Expression	[24]
NADH-cytochrome b5 reductase 3 (CYB5R3)	OTUGT3G8	NB5R3_HUMAN	Increases Expression	[24]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Increases Expression	[24]
Low-density lipoprotein receptor (LDLR)	OTH559LU	LDLR_HUMAN	Increases Expression	[24]
Transferrin receptor protein 1 (TFRC)	OT8ZPBDL	TFR1_HUMAN	Increases Expression	[24]
Protein disulfide-isomerase (P4HB)	OTTYNYPF	PDIA1_HUMAN	Increases Expression	[24]
Transcription factor Sp1 (SP1)	OTISPT4X	SP1_HUMAN	Increases Expression	[24]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Increases Expression	[24]
Pleckstrin (PLEK)	OTB73XXA	PLEK_HUMAN	Increases Expression	[24]
Macrophage colony-stimulating factor 1 (CSF1)	OT68M7RD	CSF1_HUMAN	Decreases Expression	[24]
E3 SUMO-protein ligase EGR2 (EGR2)	OTAVQ78J	EGR2_HUMAN	Increases Expression	[24]
Bone morphogenetic protein 1 (BMP1)	OTRFFAL4	BMP1_HUMAN	Increases Expression	[24]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Decreases Expression	[24]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Increases Expression	[24]
Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1)	OT7US3NO	SIAT1_HUMAN	Increases Expression	[24]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Expression	[24]
Large ribosomal subunit protein uL30 (RPL7)	OT4WCQBE	RL7_HUMAN	Increases Expression	[24]
ETS domain-containing protein Elk-1 (ELK1)	OTH9MXD6	ELK1_HUMAN	Increases Expression	[24]
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP)	OT0DH40W	AL5AP_HUMAN	Increases Expression	[24]
Ras-related protein Rab-6A (RAB6A)	OTLS86J5	RAB6A_HUMAN	Increases Expression	[24]
DNA mismatch repair protein Msh3 (MSH3)	OTD3YPVL	MSH3_HUMAN	Increases Expression	[24]
cAMP-dependent protein kinase catalytic subunit beta (PRKACB)	OT6RMDCE	KAPCB_HUMAN	Increases Expression	[24]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A)	OTHJQ1DZ	RPB1_HUMAN	Decreases Expression	[24]
M-phase inducer phosphatase 3 (CDC25C)	OTPQI71S	MPIP3_HUMAN	Increases Expression	[24]
Adenylosuccinate lyase (ADSL)	OTSNJALL	PUR8_HUMAN	Decreases Expression	[24]
Glycerol kinase (GK)	OTK2YRA0	GLPK_HUMAN	Increases Expression	[24]
Tumor necrosis factor ligand superfamily member 8 (TNFSF8)	OTDYGDJ3	TNFL8_HUMAN	Increases Expression	[24]
DNA replication licensing factor MCM4 (MCM4)	OT19PNNG	MCM4_HUMAN	Increases Expression	[24]
Trypsin-3 (PRSS3)	OTN3S5YB	TRY3_HUMAN	Increases Expression	[24]
Prostaglandin G/H synthase 2 (PTGS2)	OT75U9M4	PGH2_HUMAN	Decreases Expression	[24]
Fibrillin-1 (FBN1)	OTYCJT63	FBN1_HUMAN	Increases Expression	[24]
Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1)	OTL1LBQJ	KI2L1_HUMAN	Increases Expression	[24]
Chromobox protein homolog 5 (CBX5)	OT8VYY84	CBX5_HUMAN	Increases Expression	[24]
Transcriptional regulator ATRX (ATRX)	OT77RSQW	ATRX_HUMAN	Decreases Expression	[24]
Small ribosomal subunit protein uS4 (RPS9)	OTPV69Q0	RS9_HUMAN	Decreases Expression	[24]
Glioma pathogenesis-related protein 1 (GLIPR1)	OT0FGQK7	GLIP1_HUMAN	Decreases Expression	[24]
Iron-responsive element-binding protein 2 (IREB2)	OT747D24	IREB2_HUMAN	Increases Expression	[24]
Deoxyribonuclease-1-like 1 (DNASE1L1)	OT9ZOFN9	DNSL1_HUMAN	Increases Expression	[24]
Cysteine--tRNA ligase, cytoplasmic (CARS1)	OTOUZF6O	SYCC_HUMAN	Increases Expression	[24]
CCAAT/enhancer-binding protein alpha (CEBPA)	OTOM9OE4	CEBPA_HUMAN	Increases Expression	[24]
Cyclin-dependent kinase inhibitor 1C (CDKN1C)	OTASTJ3Q	CDN1C_HUMAN	Increases Expression	[24]
Serpin H1 (SERPINH1)	OTKGI7BS	SERPH_HUMAN	Increases Expression	[24]
Protein Tob1 (TOB1)	OTNW949D	TOB1_HUMAN	Increases Expression	[24]
Breast cancer type 2 susceptibility protein (BRCA2)	OTF1XSV1	BRCA2_HUMAN	Increases Expression	[24]
Tyrosine-protein kinase JAK3 (JAK3)	OTQ8QW2L	JAK3_HUMAN	Increases Expression	[24]
Serine/threonine-protein kinase PLK1 (PLK1)	OTRZX45T	PLK1_HUMAN	Decreases Expression	[24]
Monocarboxylate transporter 1 (SLC16A1)	OTW1UTZ7	MOT1_HUMAN	Increases Expression	[24]
Epithelial membrane protein 3 (EMP3)	OTODMJ1D	EMP3_HUMAN	Increases Expression	[24]
Syntaxin-17 (STX17)	OT8TUN64	STX17_HUMAN	Increases Expression	[24]
Inhibin beta E chain (INHBE)	OTOI2NYG	INHBE_HUMAN	Increases Expression	[24]
Protein max (MAX)	OTKZ0YKM	MAX_HUMAN	Increases Expression	[24]
Rho-related GTP-binding protein RhoB (RHOB)	OTHQFQF7	RHOB_HUMAN	Increases Expression	[24]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Decreases Expression	[24]
General transcription factor II-I (GTF2I)	OTUYL1TQ	GTF2I_HUMAN	Increases Expression	[24]
Retinal-specific phospholipid-transporting ATPase ABCA4 (ABCA4)	OTMA4IG9	ABCA4_HUMAN	Increases Expression	[24]
C-C motif chemokine 20 (CCL20)	OTUCJY4N	CCL20_HUMAN	Increases Expression	[24]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6)	OT1SLUZH	TSG6_HUMAN	Increases Expression	[24]
Di-N-acetylchitobiase (CTBS)	OT135K92	DIAC_HUMAN	Increases Expression	[24]
Mevalonate kinase (MVK)	OTHJCUKT	KIME_HUMAN	Increases Expression	[24]
Early growth response protein 4 (EGR4)	OT4R3ECK	EGR4_HUMAN	Increases Expression	[24]
Focal adhesion kinase 1 (PTK2)	OT3Q1JDY	FAK1_HUMAN	Increases Expression	[24]
Serine/arginine-rich splicing factor 11 (SRSF11)	OTZSV6CZ	SRS11_HUMAN	Decreases Expression	[24]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Decreases Expression	[24]
Disks large homolog 1 (DLG1)	OTCRZYWT	DLG1_HUMAN	Increases Expression	[24]
5-hydroxytryptamine receptor 4 (HTR4)	OTBIB44K	5HT4R_HUMAN	Increases Expression	[24]
Four and a half LIM domains protein 1 (FHL1)	OTN535SU	FHL1_HUMAN	Increases Expression	[24]
Bone morphogenetic protein receptor type-2 (BMPR2)	OTM9W547	BMPR2_HUMAN	Increases Expression	[24]
Cytochrome c oxidase copper chaperone (COX17)	OTCP4LH2	COX17_HUMAN	Decreases Expression	[24]
Protein NPAT (NPAT)	OT1ZU6JB	NPAT_HUMAN	Increases Expression	[24]
Transcription factor E2F2 (E2F2)	OTO75RM7	E2F2_HUMAN	Increases Expression	[24]
Caprin-1 (CAPRIN1)	OTEJAMS3	CAPR1_HUMAN	Increases Expression	[24]
Squalene monooxygenase (SQLE)	OT0GGRDO	ERG1_HUMAN	Increases Expression	[24]
Next to BRCA1 gene 1 protein (NBR1)	OTVRL7J9	NBR1_HUMAN	Increases Expression	[24]
Phosphatidate phosphatase LPIN1 (LPIN1)	OTQ75KF2	LPIN1_HUMAN	Increases Expression	[24]
Major vault protein (MVP)	OTJGHJRB	MVP_HUMAN	Decreases Expression	[24]
Sarcolemmal membrane-associated protein (SLMAP)	OTHW3DVC	SLMAP_HUMAN	Increases Expression	[24]
Rho GTPase-activating protein 19 (ARHGAP19)	OTD046KA	RHG19_HUMAN	Decreases Expression	[24]
Josephin-1 (JOSD1)	OT6BAFAY	JOS1_HUMAN	Increases Expression	[24]
Leucine-rich repeat-containing protein 14 (LRRC14)	OT8J4J5E	LRC14_HUMAN	Increases Expression	[24]
Protein SSXT (SS18)	OTDKHN1E	SSXT_HUMAN	Increases Expression	[24]
Nuclear factor erythroid 2-related factor 2 (NFE2L2)	OT0HENJ5	NF2L2_HUMAN	Increases Expression	[24]
Neuronal regeneration-related protein (NREP)	OT2AZPKK	NREP_HUMAN	Increases Expression	[24]
Fascin (FSCN1)	OTTGIHTM	FSCN1_HUMAN	Increases Expression	[24]
Laminin subunit alpha-3 (LAMA3)	OTFME7HT	LAMA3_HUMAN	Increases Expression	[24]
Protein Shroom1 (SHROOM1)	OTUP99ZD	SHRM1_HUMAN	Increases Expression	[24]
Proline and serine-rich protein 3 (PROSER3)	OTOIA942	PRSR3_HUMAN	Increases Expression	[24]
Cytoplasmic tRNA 2-thiolation protein 2 (CTU2)	OT323X9J	CTU2_HUMAN	Decreases Expression	[24]
Membrane metallo-endopeptidase-like 1 (MMEL1)	OTOGJEXZ	MMEL1_HUMAN	Increases Expression	[24]
Membralin (TMEM259)	OTVH9HD8	MBRL_HUMAN	Increases Expression	[24]
Protein lin-52 homolog (LIN52)	OT14OQ1C	LIN52_HUMAN	Increases Expression	[24]
Akirin-2 (AKIRIN2)	OTQ6WSKW	AKIR2_HUMAN	Decreases Expression	[24]
N-acetyltransferase ESCO2 (ESCO2)	OTJEMAQU	ESCO2_HUMAN	Increases Expression	[24]
Probable E3 ubiquitin-protein ligase HERC4 (HERC4)	OTU4DSDE	HERC4_HUMAN	Decreases Expression	[24]
Heterochromatin protein 1-binding protein 3 (HP1BP3)	OTTJ5LX2	HP1B3_HUMAN	Increases Expression	[24]
NEDD4-binding protein 2-like 1 (N4BP2L1)	OTEGV3GO	N42L1_HUMAN	Increases Expression	[24]
RNA-binding E3 ubiquitin-protein ligase MEX3C (MEX3C)	OT8AJG1I	MEX3C_HUMAN	Increases Expression	[24]
Triple QxxK/R motif-containing protein (TRIQK)	OT2BXCL0	TRIQK_HUMAN	Increases Expression	[24]
DDB1- and CUL4-associated factor 15 (DCAF15)	OTWBXZ0E	DCA15_HUMAN	Increases Expression	[24]
AT-rich interactive domain-containing protein 2 (ARID2)	OTIRJXWM	ARID2_HUMAN	Decreases Expression	[24]
Rhomboid domain-containing protein 2 (RHBDD2)	OTX54ILM	RHBD2_HUMAN	Increases Expression	[24]
Long-chain fatty acid transport protein 1 (SLC27A1)	OTK03OZN	S27A1_HUMAN	Increases Expression	[24]
Proline/serine-rich coiled-coil protein 1 (PSRC1)	OT7MDJMN	PSRC1_HUMAN	Decreases Expression	[24]
Fidgetin-like protein 1 (FIGNL1)	OTKII63K	FIGL1_HUMAN	Increases Expression	[24]
Transmembrane and coiled-coil domain-containing protein 3 (TMCO3)	OTYW1KP2	TMCO3_HUMAN	Increases Expression	[24]
Bombesin receptor-activated protein C6orf89 (C6ORF89)	OTESX51F	CF089_HUMAN	Increases Expression	[24]
BICD family-like cargo adapter 1 (BICDL1)	OTLN65IU	BICL1_HUMAN	Increases Expression	[24]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L)	OTSP1W0F	MD13L_HUMAN	Decreases Expression	[24]
Transcription termination factor 4, mitochondrial (MTERF4)	OT50CTOJ	MTEF4_HUMAN	Increases Expression	[24]
Polycomb group RING finger protein 5 (PCGF5)	OTDF5C72	PCGF5_HUMAN	Increases Expression	[24]
Dipeptidyl peptidase 9 (DPP9)	OTBMZW2O	DPP9_HUMAN	Increases Expression	[24]
ATP-dependent RNA helicase DDX42 (DDX42)	OT93XO40	DDX42_HUMAN	Increases Expression	[24]
Centrosomal protein of 57 kDa (CEP57)	OTPOHLIX	CEP57_HUMAN	Increases Expression	[24]
Interferon regulatory factor 2-binding protein 1 (IRF2BP1)	OT9Q1V8N	I2BP1_HUMAN	Decreases Expression	[24]
MAP7 domain-containing protein 3 (MAP7D3)	OTB7ZTPO	MA7D3_HUMAN	Increases Expression	[24]
Kelch repeat and BTB domain-containing protein 2 (KBTBD2)	OTGH5XJC	KBTB2_HUMAN	Increases Expression	[24]
E3 ubiquitin-protein ligase TRIM22 (TRIM22)	OTJBLG5R	TRI22_HUMAN	Increases Expression	[24]
Regulatory-associated protein of mTOR (RPTOR)	OT4TQZ9F	RPTOR_HUMAN	Decreases Expression	[24]
Serine/threonine-protein kinase 40 (STK40)	OT4R325X	STK40_HUMAN	Decreases Expression	[24]
Rho GTPase-activating protein 18 (ARHGAP18)	OTYMJP6H	RHG18_HUMAN	Decreases Expression	[24]
Protein O-mannosyl-transferase TMTC2 (TMTC2)	OTY1QWYU	TMTC2_HUMAN	Increases Expression	[24]
T-cell activation inhibitor, mitochondrial (TCAIM)	OTOBD7YO	TCAIM_HUMAN	Increases Expression	[24]
Misshapen-like kinase 1 (MINK1)	OTKB0RA8	MINK1_HUMAN	Decreases Expression	[24]
Melanoregulin (MREG)	OT0LUIRG	MREG_HUMAN	Increases Expression	[24]
Centrosomal protein of 120 kDa (CEP120)	OT1ZMRHL	CE120_HUMAN	Increases Expression	[24]
Probable E3 ubiquitin-protein ligase DTX3 (DTX3)	OTSUUV9N	DTX3_HUMAN	Increases Expression	[24]
tRNA-uridine aminocarboxypropyltransferase 2 (DTWD2)	OTI2NKKV	DTWD2_HUMAN	Decreases Expression	[24]
Kelch-like protein 23 (KLHL23)	OT2UVSD2	KLH23_HUMAN	Increases Expression	[24]
Acyl-CoA-binding domain-containing protein 4 (ACBD4)	OTVR7MLK	ACBD4_HUMAN	Decreases Expression	[24]
SPRY domain-containing protein 3 (SPRYD3)	OTW4IDEK	SPRY3_HUMAN	Decreases Expression	[24]
Dual specificity protein phosphatase 18 (DUSP18)	OTRGTS73	DUS18_HUMAN	Increases Expression	[24]
Protein Lines homolog 1 (LINS1)	OT1USO08	LINES_HUMAN	Increases Expression	[24]
Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40)	OTYMJ69D	S2540_HUMAN	Increases Expression	[24]
TLC domain-containing protein 3A (TLCD3A)	OTVZUR1Z	TLC3A_HUMAN	Increases Expression	[24]
Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC1S5)	OTE3LL6Q	BL1S5_HUMAN	Increases Expression	[24]
Protein FAM222B (FAM222B)	OTV9TL5C	F222B_HUMAN	Decreases Expression	[24]
RING finger protein 141 (RNF141)	OT07ANSG	RN141_HUMAN	Decreases Expression	[24]
Soluble calcium-activated nucleotidase 1 (CANT1)	OT1TPWQR	CANT1_HUMAN	Increases Expression	[24]
Ras association domain-containing protein 5 (RASSF5)	OT6Q41I2	RASF5_HUMAN	Increases Expression	[24]
HMG box transcription factor BBX (BBX)	OTNQ3QUC	BBX_HUMAN	Decreases Expression	[24]
Nanos homolog 1 (NANOS1)	OT3UNZZY	NANO1_HUMAN	Increases Expression	[24]
Intraflagellar transport protein 81 homolog (IFT81)	OTB23T17	IFT81_HUMAN	Decreases Expression	[24]
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGNT1)	OTBNOUZC	PMGT1_HUMAN	Increases Expression	[24]
DCN1-like protein 4 (DCUN1D4)	OTIEGOZ0	DCNL4_HUMAN	Increases Expression	[24]
Centromere protein I (CENPI)	OTWRIMZ3	CENPI_HUMAN	Increases Expression	[24]
Golgi apparatus protein 1 (GLG1)	OT7X0W3N	GSLG1_HUMAN	Decreases Expression	[24]
Selenocysteine insertion sequence-binding protein 2-like (SECISBP2L)	OTMSOLZU	SBP2L_HUMAN	Increases Expression	[24]
Proline-rich AKT1 substrate 1 (AKT1S1)	OT4JHN4Y	AKTS1_HUMAN	Increases Expression	[24]
Gamma-secretase subunit APH-1A (APH1A)	OT97F1TU	APH1A_HUMAN	Increases Expression	[24]
Calmodulin-like protein 4 (CALML4)	OT6DD5EW	CALL4_HUMAN	Decreases Expression	[24]
Serine/Arginine-related protein 53 (RSRC1)	OTFCJ4S0	RSRC1_HUMAN	Decreases Expression	[24]
Transmembrane protein 87B (TMEM87B)	OTXT7BCU	TM87B_HUMAN	Increases Expression	[24]
ADP-ribosylation factor-like protein 5B (ARL5B)	OTYYBIDG	ARL5B_HUMAN	Increases Expression	[24]
Prolyl hydroxylase EGLN2 (EGLN2)	OT0FC1YX	EGLN2_HUMAN	Increases Expression	[24]
Peptidoglycan recognition protein 4 (PGLYRP4)	OTI115BR	PGRP4_HUMAN	Increases Expression	[24]
Coiled-coil domain-containing protein 138 (CCDC138)	OTT1TXO8	CC138_HUMAN	Increases Expression	[24]
Centrosomal protein 20 (CEP20)	OTLNQ7ZW	CEP20_HUMAN	Increases Expression	[24]
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1)	OTINOJJ7	ARAP1_HUMAN	Decreases Expression	[24]
AP-1 complex subunit sigma-3 (AP1S3)	OTPCMV24	AP1S3_HUMAN	Increases Expression	[24]
RNA-binding protein 14 (RBM14)	OTO9GMBD	RBM14_HUMAN	Increases Expression	[24]
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2)	OT3MEGIU	ERGI2_HUMAN	Decreases Expression	[24]
Tribbles homolog 3 (TRIB3)	OTG5OS7X	TRIB3_HUMAN	Increases Expression	[24]
TSC22 domain family protein 3 (TSC22D3)	OT03UM03	T22D3_HUMAN	Increases Expression	[24]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)	OTJGE772	CHAC1_HUMAN	Increases Expression	[24]
E3 ubiquitin-protein ligase TRAIP (TRAIP)	OTMPT9Y2	TRAIP_HUMAN	Increases Expression	[24]
Sideroflexin-3 (SFXN3)	OTM6UWNH	SFXN3_HUMAN	Decreases Expression	[24]
Proline-rich protein 14 (PRR14)	OTZMIMOK	PRR14_HUMAN	Increases Expression	[24]
GTP-binding protein 2 (GTPBP2)	OTOJ1KUA	GTPB2_HUMAN	Increases Expression	[24]
Fanconi anemia group J protein (BRIP1)	OT38QBD4	FANCJ_HUMAN	Increases Expression	[24]
Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4)	OT2SZQI7	TMG4_HUMAN	Increases Expression	[24]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Increases Expression	[24]
Apoptosis inhibitor 5 (API5)	OTYX9YCZ	API5_HUMAN	Increases Expression	[24]
Centrosomal protein of 295 kDa (CEP295)	OTVTTXRO	CE295_HUMAN	Increases Expression	[24]
Toll-interacting protein (TOLLIP)	OTYEO4NR	TOLIP_HUMAN	Increases Expression	[24]
Charged multivesicular body protein 4b (CHMP4B)	OT854ZK7	CHM4B_HUMAN	Increases Expression	[24]
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (OSGEPL1)	OTT32BWT	OSGL1_HUMAN	Decreases Expression	[24]
Zinc finger protein Pegasus (IKZF5)	OTJN51OC	IKZF5_HUMAN	Decreases Expression	[24]
Probable ATP-dependent RNA helicase DHX35 (DHX35)	OTOP4UCG	DHX35_HUMAN	Increases Expression	[24]
E3 ubiquitin-protein ligase RNF167 (RNF167)	OTNNKBYS	RN167_HUMAN	Increases Expression	[24]
Mediator of RNA polymerase II transcription subunit 20 (MED20)	OTWLPQAP	MED20_HUMAN	Increases Expression	[24]
Guanine nucleotide-binding protein subunit beta-4 (GNB4)	OTC1GPHA	GBB4_HUMAN	Increases Expression	[24]
Transcription initiation factor TFIID subunit 9B (TAF9B)	OTORBI4I	TAF9B_HUMAN	Increases Expression	[24]
Echinoderm microtubule-associated protein-like 4 (EML4)	OTJC45TA	EMAL4_HUMAN	Increases Expression	[24]
Interleukin-23 subunit alpha (IL23A)	OTYO99HC	IL23A_HUMAN	Increases Expression	[24]
Lysine-rich coiled-coil protein 1 (KRCC1)	OTMMV6WZ	KRCC1_HUMAN	Increases Expression	[24]
Proline-rich nuclear receptor coactivator 2 (PNRC2)	OTE7W7Y5	PNRC2_HUMAN	Increases Expression	[24]
NTF2-related export protein 2 (NXT2)	OTK82YVT	NXT2_HUMAN	Increases Expression	[24]
PDZ and LIM domain protein 7 (PDLIM7)	OTAZVODU	PDLI7_HUMAN	Increases Expression	[24]
14 kDa phosphohistidine phosphatase (PHPT1)	OTFYWNFX	PHP14_HUMAN	Increases Expression	[24]
Ankyrin repeat and EF-hand domain-containing protein 1 (ANKEF1)	OTFH7ZM3	ANKE1_HUMAN	Increases Expression	[24]
Cell cycle control protein 50A (TMEM30A)	OTR6N5J2	CC50A_HUMAN	Increases Expression	[24]
Poly(A) RNA polymerase, mitochondrial (MTPAP)	OT6HQ02S	PAPD1_HUMAN	Increases Expression	[24]
Nuclear distribution protein nudE homolog 1 (NDE1)	OT2N8Q17	NDE1_HUMAN	Increases Expression	[24]
Ankyrin repeat domain-containing protein 10 (ANKRD10)	OTIZ2VK8	ANR10_HUMAN	Increases Expression	[24]
BTB/POZ domain-containing protein KCTD5 (KCTD5)	OTTTHS89	KCTD5_HUMAN	Increases Expression	[24]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2)	OTPZK76F	TAB2_HUMAN	Increases Expression	[24]
Spermatogenesis-associated protein 7 (SPATA7)	OT78G2IH	SPAT7_HUMAN	Increases Expression	[24]
Tuftelin-interacting protein 11 (TFIP11)	OT7NVSWU	TFP11_HUMAN	Decreases Expression	[24]
LIM/homeobox protein Lhx3 (LHX3)	OTQ5BAJ9	LHX3_HUMAN	Increases Expression	[24]
DnaJ homolog subfamily B member 9 (DNAJB9)	OT38EQT6	DNJB9_HUMAN	Increases Expression	[24]
Solute carrier family 23 member 2 (SLC23A2)	OTJ5CQMA	S23A2_HUMAN	Increases Expression	[24]
Prenylcysteine oxidase 1 (PCYOX1)	OT8FBKY0	PCYOX_HUMAN	Increases Expression	[24]
Solute carrier organic anion transporter family member 3A1 (SLCO3A1)	OTME93NY	SO3A1_HUMAN	Decreases Expression	[24]
Short coiled-coil protein (SCOC)	OTPJ3RQ4	SCOC_HUMAN	Increases Expression	[24]
Leucyl-cystinyl aminopeptidase (LNPEP)	OTOKXPL3	LCAP_HUMAN	Increases Expression	[24]
Cardiolipin synthase (CRLS1)	OT7XNL0K	CRLS1_HUMAN	Decreases Expression	[24]
Protein fem-1 homolog B (FEM1B)	OTFE2ELA	FEM1B_HUMAN	Increases Expression	[24]
Paired immunoglobulin-like type 2 receptor beta (PILRB)	OTWKZZRM	PILRB_HUMAN	Increases Expression	[24]
General transcription factor 3C polypeptide 4 (GTF3C4)	OT4YPF27	TF3C4_HUMAN	Increases Expression	[24]
Protein CDV3 homolog (CDV3)	OTUA175T	CDV3_HUMAN	Increases Expression	[24]
Ras-related protein Rab-23 (RAB23)	OTBAKFBR	RAB23_HUMAN	Increases Expression	[24]
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1)	OTZTE1PG	DAPP1_HUMAN	Increases Expression	[24]
Transcription factor SOX-13 (SOX13)	OTCIF6KC	SOX13_HUMAN	Increases Expression	[24]
Afadin- and alpha-actinin-binding protein (SSX2IP)	OTEIZ7N1	ADIP_HUMAN	Increases Expression	[24]
Caspase recruitment domain-containing protein 8 (CARD8)	OTXXZYWU	CARD8_HUMAN	Increases Expression	[24]
Disks large-associated protein 4 (DLGAP4)	OTNELLIN	DLGP4_HUMAN	Decreases Expression	[24]
Mitogen-activated protein kinase kinase kinase 2 (MAP3K2)	OTI7MCML	M3K2_HUMAN	Decreases Expression	[24]
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (COQ4)	OTIU7FAZ	COQ4_HUMAN	Decreases Expression	[24]
Nuclear factor erythroid 2-related factor 3 (NFE2L3)	OT1MGXT0	NF2L3_HUMAN	Decreases Expression	[24]
E3 ubiquitin-protein ligase RNF114 (RNF114)	OTF06FRP	RN114_HUMAN	Increases Expression	[24]
Transportin-3 (TNPO3)	OTOT3HH0	TNPO3_HUMAN	Decreases Expression	[24]
Olfactory receptor 51B2 (OR51B2)	OT3ZQRVM	O51B2_HUMAN	Increases Expression	[24]
Fatty acid desaturase 3 (FADS3)	OT9RVXGE	FADS3_HUMAN	Increases Expression	[24]
RNA-binding protein 8A (RBM8A)	OT5SR6G0	RBM8A_HUMAN	Increases Expression	[24]
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)	OTK53GUD	HS3SB_HUMAN	Decreases Expression	[24]
Protein shisa-3 homolog (SHISA3)	OTE8TPCP	SHSA3_HUMAN	Decreases Expression	[25]
Transmembrane protein 72 (TMEM72)	OT6V5TCP	TMM72_HUMAN	Decreases Expression	[25]
Solute carrier family 22 member 23 (SLC22A23)	OT56BVY1	S22AN_HUMAN	Increases Expression	[25]
Transmembrane protein 213 (TMEM213)	OTRXSK61	TM213_HUMAN	Decreases Expression	[25]
Killer cell lectin-like receptor subfamily G member 2 (KLRG2)	OTBLEXSC	KLRG2_HUMAN	Increases Expression	[25]
Multiple epidermal growth factor-like domains protein 11 (MEGF11)	OTVXC2YH	MEG11_HUMAN	Increases Expression	[25]
Ciliary microtubule inner protein 2C (CIMIP2C)	OTKXQKQ4	CMI2C_HUMAN	Decreases Expression	[25]
Ankyrin repeat and BTB/POZ domain-containing protein 3 (ABTB3)	OT3PLG38	ABTB3_HUMAN	Decreases Expression	[25]
Uncharacterized protein C15orf62, mitochondrial (C15ORF62)	OT2VU9TN	CO062_HUMAN	Increases Expression	[25]
Isthmin-1 (ISM1)	OTZTK2TV	ISM1_HUMAN	Increases Expression	[25]
Metabotropic glutamate receptor 8 (GRM8)	OTUEMDCA	GRM8_HUMAN	Decreases Expression	[25]
Signal-regulatory protein beta-1 (SIRPB1)	OTGHALWJ	SIRB1_HUMAN	Increases Expression	[25]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)	OTKOZRZP	PLOD2_HUMAN	Increases Expression	[25]
Gamma-aminobutyric acid receptor subunit pi (GABRP)	OTGKA8WS	GBRP_HUMAN	Decreases Expression	[25]
Phospholipid phosphatase 3 (PLPP3)	OTSSF7BK	PLPP3_HUMAN	Increases Expression	[25]
Nck-associated protein 5 (NCKAP5)	OT5JOYZS	NCKP5_HUMAN	Increases Expression	[25]
Cdc42 effector protein 2 (CDC42EP2)	OTX3YDPN	BORG1_HUMAN	Increases Expression	[25]
Heparan sulfate glucosamine 3-O-sulfotransferase 1 (HS3ST1)	OT5DVN9P	HS3S1_HUMAN	Increases Expression	[25]
SH2 domain-containing protein 1B (SH2D1B)	OTZG59LW	SH21B_HUMAN	Increases Expression	[25]
Protocadherin-17 (PCDH17)	OTRK0M05	PCD17_HUMAN	Increases Expression	[25]
Long-chain fatty acid transport protein 2 (SLC27A2)	OT7JEG5F	S27A2_HUMAN	Decreases Expression	[25]
Microtubule-associated serine/threonine-protein kinase 4 (MAST4)	OT3LOE2J	MAST4_HUMAN	Increases Expression	[25]
Syntaphilin (SNPH)	OTL6XBFA	SNPH_HUMAN	Increases Expression	[25]
FYN-binding protein 1 (FYB1)	OT6345CH	FYB1_HUMAN	Decreases Expression	[25]
Muscle, skeletal receptor tyrosine-protein kinase (MUSK)	OTERKP1U	MUSK_HUMAN	Decreases Expression	[25]
Phospholipid scramblase 1 (PLSCR1)	OTGY9B5T	PLS1_HUMAN	Increases Expression	[25]
Matrilin-3 (MATN3)	OTH9H74J	MATN3_HUMAN	Decreases Expression	[25]
E3 ubiquitin-protein ligase Midline-1 (MID1)	OTWN1PGU	TRI18_HUMAN	Increases Expression	[25]
High mobility group protein B3 (HMGB3)	OTCJ2EZY	HMGB3_HUMAN	Increases Expression	[25]
Monocarboxylate transporter 5 (SLC16A4)	OT1YXBKC	MOT5_HUMAN	Decreases Expression	[25]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Decreases Expression	[25]
Transmembrane protease serine 2 (TMPRSS2)	OTN44YQ5	TMPS2_HUMAN	Increases Expression	[25]
ATP-binding cassette sub-family C member 5 (ABCC5)	OT34G4US	MRP5_HUMAN	Decreases Expression	[25]
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2)	OTP45YKX	P4HA2_HUMAN	Increases Expression	[25]
Insulin-induced gene 1 protein (INSIG1)	OTZF5X1D	INSI1_HUMAN	Increases Expression	[25]
CASP8 and FADD-like apoptosis regulator (CFLAR)	OTX14BAS	CFLAR_HUMAN	Increases Expression	[25]
Suppressor of cytokine signaling 1 (SOCS1)	OTWA9KFU	SOCS1_HUMAN	Increases Expression	[25]
Tapasin (TAPBP)	OTL81AVZ	TPSN_HUMAN	Increases Expression	[25]
D-3-phosphoglycerate dehydrogenase (PHGDH)	OT1LMRTG	SERA_HUMAN	Decreases Expression	[25]
Interleukin-1 receptor-associated kinase-like 2 (IRAK2)	OT6Y1QZN	IRAK2_HUMAN	Increases Expression	[25]
Kallikrein-10 (KLK10)	OTD573EL	KLK10_HUMAN	Increases Expression	[25]
SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3)	OT9ZS72C	SRGP3_HUMAN	Increases Expression	[25]
Heat shock 70 kDa protein 12A (HSPA12A)	OTFOCDD6	HS12A_HUMAN	Decreases Expression	[25]
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2)	OT0KMIYQ	RIPK2_HUMAN	Increases Expression	[25]
Protein Mis18-beta (OIP5)	OTI5C2DE	MS18B_HUMAN	Decreases Expression	[25]
Prominin-1 (PROM1)	OTBHV8NX	PROM1_HUMAN	Increases Expression	[25]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[25]
LIM domain-binding protein 2 (LDB2)	OT6Y8IEK	LDB2_HUMAN	Increases Expression	[25]
A-kinase anchor protein 7 isoforms alpha and beta (AKAP7)	OT0L3PZ6	AKA7A_HUMAN	Decreases Expression	[25]
Glucose-6-phosphate exchanger SLC37A4 (SLC37A4)	OTLCYA32	G6PT1_HUMAN	Increases Expression	[25]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7)	OTHS1L0E	GBG7_HUMAN	Decreases Expression	[25]
TBC1 domain family member 4 (TBC1D4)	OTK66C40	TBCD4_HUMAN	Decreases Expression	[25]
Periplakin (PPL)	OTTM4WDO	PEPL_HUMAN	Decreases Expression	[25]
Myelin protein zero-like protein 2 (MPZL2)	OTKFNDUI	MPZL2_HUMAN	Increases Expression	[25]
Cubilin (CUBN)	OT5A9HD3	CUBN_HUMAN	Increases Expression	[25]
Toll-like receptor 5 (TLR5)	OT8ZYKJ6	TLR5_HUMAN	Increases Expression	[25]
Immunoglobulin mu Fc receptor (FCMR)	OTI7I47T	FCMR_HUMAN	Increases Expression	[25]
Tyrosine-protein kinase JAK2 (JAK2)	OTBIDOOR	JAK2_HUMAN	Increases Expression	[25]
Protein-tyrosine sulfotransferase 2 (TPST2)	OT2XKFCE	TPST2_HUMAN	Decreases Expression	[25]
Cytohesin-interacting protein (CYTIP)	OTRJ3ZC5	CYTIP_HUMAN	Increases Expression	[25]
Histone H2B type 1-K (H2BC12)	OTQ8V0KG	H2B1K_HUMAN	Increases Expression	[25]
G-protein coupled receptor 37-like 1 (GPR37L1)	OTOV08EV	G37L1_HUMAN	Increases Expression	[25]
Low-density lipoprotein receptor-related protein 3 (LRP3)	OTXMLT8C	LRP3_HUMAN	Decreases Expression	[25]
ICOS ligand (ICOSLG)	OTAD976B	ICOSL_HUMAN	Increases Expression	[25]
Small integral membrane protein 24 (SMIM24)	OTSYU3S9	SIM24_HUMAN	Decreases Expression	[25]
Hyaluronan mediated motility receptor (HMMR)	OT4M0JTZ	HMMR_HUMAN	Decreases Expression	[25]
Cell division control protein 45 homolog (CDC45)	OT6NNLOD	CDC45_HUMAN	Decreases Expression	[25]
Glypican-4 (GPC4)	OTUJ14DW	GPC4_HUMAN	Decreases Expression	[25]
Mammaglobin-B (SCGB2A1)	OT9L87U9	SG2A1_HUMAN	Increases Expression	[25]
PR domain zinc finger protein 1 (PRDM1)	OTQLSVBS	PRDM1_HUMAN	Increases Expression	[25]
Serpin B7 (SERPINB7)	OTZ95LR2	SPB7_HUMAN	Increases Expression	[25]
Paralemmin-1 (PALM)	OTTZONUX	PALM_HUMAN	Decreases Expression	[25]
Lathosterol oxidase (SC5D)	OT41KMW4	SC5D_HUMAN	Increases Expression	[25]
Matrix metalloproteinase-23 (MMP23B)	OT2OR6TS	MMP23_HUMAN	Increases Expression	[25]
Short-chain dehydrogenase/reductase 3 (DHRS3)	OTSK1DTP	DHRS3_HUMAN	Decreases Expression	[25]
Gamma-butyrobetaine dioxygenase (BBOX1)	OTKEX4RK	BODG_HUMAN	Decreases Expression	[25]
Stanniocalcin-2 (STC2)	OT86YP8G	STC2_HUMAN	Increases Expression	[25]
Delta(14)-sterol reductase TM7SF2 (TM7SF2)	OTILU5S7	ERG24_HUMAN	Increases Expression	[25]
cGMP-specific 3',5'-cyclic phosphodiesterase (PDE5A)	OTT8Q1AP	PDE5A_HUMAN	Decreases Expression	[25]
Fibroblast growth factor 18 (FGF18)	OTO7KJF8	FGF18_HUMAN	Increases Expression	[25]
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH1)	OT1U2GWG	DDAH1_HUMAN	Decreases Expression	[25]
Phospholipid-transporting ATPase VB (ATP10B)	OTSOUTE1	AT10B_HUMAN	Increases Expression	[25]
Rho-related BTB domain-containing protein 1 (RHOBTB1)	OTGE8K45	RHBT1_HUMAN	Decreases Expression	[25]
Transmembrane and coiled-coil domains protein 1 (TMCC1)	OTRXDL86	TMCC1_HUMAN	Decreases Expression	[25]
SAM and SH3 domain-containing protein 1 (SASH1)	OTQA8BD4	SASH1_HUMAN	Decreases Expression	[25]
Dickkopf-related protein 1 (DKK1)	OTRDLUSP	DKK1_HUMAN	Decreases Expression	[25]
D-glucuronyl C5-epimerase (GLCE)	OTPRSHX5	GLCE_HUMAN	Increases Expression	[25]
Rho-related BTB domain-containing protein 3 (RHOBTB3)	OT1BFKPH	RHBT3_HUMAN	Decreases Expression	[25]
Solute carrier organic anion transporter family member 2B1 (SLCO2B1)	OTERJ4VQ	SO2B1_HUMAN	Increases Expression	[25]
E3 ubiquitin-protein ligase TRIM37 (TRIM37)	OTP6VI99	TRI37_HUMAN	Increases Expression	[25]
G2/mitotic-specific cyclin-B2 (CCNB2)	OTIEXTDK	CCNB2_HUMAN	Decreases Expression	[25]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Decreases Expression	[25]
Tumor necrosis factor ligand superfamily member 15 (TNFSF15)	OTNGA2BW	TNF15_HUMAN	Increases Expression	[25]
Sciellin (SCEL)	OT46SDNQ	SCEL_HUMAN	Decreases Expression	[25]
RCC1 and BTB domain-containing protein 2 (RCBTB2)	OTECBF4R	RCBT2_HUMAN	Increases Expression	[25]
Chromosome-associated kinesin KIF4A (KIF4A)	OT3UWL7D	KIF4A_HUMAN	Decreases Expression	[25]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G)	OT8V1J4M	GA45G_HUMAN	Increases Expression	[25]
Potassium voltage-gated channel subfamily H member 1 (KCNH1)	OTZZXWER	KCNH1_HUMAN	Decreases Expression	[25]
RAS guanyl-releasing protein 1 (RASGRP1)	OTX9WN2E	GRP1_HUMAN	Increases Expression	[25]
RasGAP-activating-like protein 1 (RASAL1)	OTAHUNN7	RASL1_HUMAN	Decreases Expression	[25]
Tripartite motif-containing protein 16 (TRIM16)	OTLRXYOZ	TRI16_HUMAN	Increases Expression	[25]
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8)	OT1G9297	TFIP8_HUMAN	Increases Expression	[25]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3)	OTQ9ALTR	GCNT3_HUMAN	Increases Expression	[25]
Supervillin (SVIL)	OTWQQ1WK	SVIL_HUMAN	Increases Expression	[25]
Sodium-dependent phosphate transport protein 2B (SLC34A2)	OTLFMBB0	NPT2B_HUMAN	Increases Expression	[25]
Claudin-14 (CLDN14)	OTS7GKOI	CLD14_HUMAN	Increases Expression	[25]
Mitochondrial pyruvate carrier 2 (MPC2)	OT0GHXGG	MPC2_HUMAN	Decreases Expression	[25]
Netrin-1 (NTN1)	OTUQH74P	NET1_HUMAN	Increases Expression	[25]
Follistatin-related protein 3 (FSTL3)	OT75489W	FSTL3_HUMAN	Decreases Expression	[25]
C-X-C motif chemokine 14 (CXCL14)	OTM189TA	CXL14_HUMAN	Decreases Expression	[25]
Protein LDOC1 (LDOC1)	OTWZH4O9	LDOC1_HUMAN	Decreases Expression	[25]
TBC1 domain family member 8 (TBC1D8)	OT2011SS	TBCD8_HUMAN	Increases Expression	[25]
Caveolae-associated protein 2 (CAVIN2)	OTFHHDRU	CAVN2_HUMAN	Decreases Expression	[25]
Guanylyl cyclase-activating protein 3 (GUCA1C)	OTAUOF7Y	GUC1C_HUMAN	Decreases Expression	[25]
Tetraspanin-15 (TSPAN15)	OTNQXXIG	TSN15_HUMAN	Increases Expression	[25]
Acyl-CoA 6-desaturase (FADS2)	OTUX531P	FADS2_HUMAN	Increases Expression	[25]
Secretoglobin family 1D member 2 (SCGB1D2)	OTSYWZAQ	SG1D2_HUMAN	Increases Expression	[25]
Actin-associated protein FAM107A (FAM107A)	OTBG61YZ	F107A_HUMAN	Increases Expression	[25]
Anterior gradient protein 2 homolog (AGR2)	OTRRZT7W	AGR2_HUMAN	Decreases Expression	[25]
Ceruloplasmin (CP)	OTM8JE4Y	CERU_HUMAN	Increases Expression	[25]
Complement C1r subcomponent (C1R)	OTA0ZNIU	C1R_HUMAN	Increases Expression	[25]
Tissue-type plasminogen activator (PLAT)	OTQPDNAB	TPA_HUMAN	Increases Expression	[25]
Complement factor B (CFB)	OTZITNEJ	CFAB_HUMAN	Increases Expression	[25]
Serine protease inhibitor Kazal-type 1 (SPINK1)	OTSUVAL2	ISK1_HUMAN	Increases Expression	[25]
Alpha-1-antitrypsin (SERPINA1)	OTACYW9J	A1AT_HUMAN	Increases Expression	[25]
Alpha-1-antichymotrypsin (SERPINA3)	OT9BP2S0	AACT_HUMAN	Increases Expression	[25]
Complement C3 (C3)	OTCH5GS0	CO3_HUMAN	Increases Expression	[25]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Decreases Expression	[25]
Interleukin-1 beta (IL1B)	OT0DWXXB	IL1B_HUMAN	Increases Expression	[25]
Polymeric immunoglobulin receptor (PIGR)	OT6GLSUL	PIGR_HUMAN	Increases Expression	[25]
HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA)	OT7KZMP2	DRA_HUMAN	Increases Expression	[25]
HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1)	OTRGGIFP	DRB1_HUMAN	Increases Expression	[25]
Alpha-crystallin B chain (CRYAB)	OTY4JGYU	CRYAB_HUMAN	Increases Expression	[25]
Prelamin-A/C (LMNA)	OT3SG7ZR	LMNA_HUMAN	Decreases Expression	[25]
Leucine-rich alpha-2-glycoprotein (LRG1)	OTLD0KWA	A2GL_HUMAN	Increases Expression	[25]
Platelet basic protein (PPBP)	OT1FHGQS	CXCL7_HUMAN	Increases Expression	[25]
C-X-C motif chemokine 10 (CXCL10)	OTTLQ6S0	CXL10_HUMAN	Increases Expression	[25]
Metallothionein-2 (MT2A)	OTHOACHD	MT2_HUMAN	Increases Expression	[25]
Antileukoproteinase (SLPI)	OTUNFUU8	SLPI_HUMAN	Increases Expression	[25]
C4b-binding protein alpha chain (C4BPA)	OTHNH6Y8	C4BPA_HUMAN	Increases Expression	[25]
Tissue alpha-L-fucosidase (FUCA1)	OTW71IK4	FUCO_HUMAN	Increases Expression	[25]
Granulocyte-macrophage colony-stimulating factor (CSF2)	OT1M7D28	CSF2_HUMAN	Increases Expression	[25]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Increases Expression	[25]
HLA class II histocompatibility antigen gamma chain (CD74)	OTO16X4Q	HG2A_HUMAN	Increases Expression	[25]
HLA class I histocompatibility antigen, A alpha chain (HLA-A)	OTAH14LU	HLAA_HUMAN	Increases Expression	[25]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[25]
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)	OTCJ458Q	AT1A1_HUMAN	Decreases Expression	[25]
Integrin beta-2 (ITGB2)	OTEKPEPR	ITB2_HUMAN	Increases Expression	[25]
Cytochrome P450 1A2 (CYP1A2)	OTLLBX48	CP1A2_HUMAN	Increases Expression	[25]
Endothelin-1 (EDN1)	OTZCACEG	EDN1_HUMAN	Increases Expression	[25]
Neuroendocrine protein 7B2 (SCG5)	OTXSJMT1	7B2_HUMAN	Increases Expression	[25]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Decreases Expression	[25]
Cholinesterase (BCHE)	OTOH3WQ9	CHLE_HUMAN	Decreases Expression	[25]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Decreases Expression	[25]
Protein S100-A9 (S100A9)	OTOARHCS	S10A9_HUMAN	Increases Expression	[25]
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)	OTREV92I	CEAM5_HUMAN	Increases Expression	[25]
Neurofilament light polypeptide (NEFL)	OTQESJV4	NFL_HUMAN	Decreases Expression	[25]
Neurofilament medium polypeptide (NEFM)	OT8VCBNF	NFM_HUMAN	Decreases Expression	[25]
Alcohol dehydrogenase 1A (ADH1A)	OTTS983E	ADH1A_HUMAN	Decreases Expression	[25]
Bisphosphoglycerate mutase (BPGM)	OTFX6527	PMGE_HUMAN	Increases Expression	[25]
Laminin subunit beta-1 (LAMB1)	OT6J9LJR	LAMB1_HUMAN	Decreases Expression	[25]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Increases Expression	[25]
Thrombospondin-1 (THBS1)	OT0ECWK3	TSP1_HUMAN	Decreases Expression	[25]
Gap junction beta-1 protein (GJB1)	OT0F7OLN	CXB1_HUMAN	Decreases Expression	[25]
Amino acid transporter heavy chain SLC3A2 (SLC3A2)	OTBR33M9	4F2_HUMAN	Decreases Expression	[25]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Decreases Expression	[25]
Extracellular superoxide dismutase (SOD3)	OTIOZQAB	SODE_HUMAN	Increases Expression	[25]
Monocyte differentiation antigen CD14 (CD14)	OT83GJ47	CD14_HUMAN	Increases Expression	[25]
Myosin light chain 3 (MYL3)	OTKD3RSX	MYL3_HUMAN	Decreases Expression	[25]
Alpha-2-antiplasmin (SERPINF2)	OTZGAF8B	A2AP_HUMAN	Decreases Expression	[25]
Fibrocystin (PKHD1)	OTAH8SMF	PKHD1_HUMAN	Decreases Expression	[25]
Fibroblast growth factor 2 (FGF2)	OT7YUJ9F	FGF2_HUMAN	Decreases Expression	[25]
Cystatin-SA (CST2)	OTRKRW50	CYTT_HUMAN	Increases Expression	[25]
Stromelysin-2 (MMP10)	OTJDWW8Q	MMP10_HUMAN	Increases Expression	[25]
Growth-regulated alpha protein (CXCL1)	OT3WCTZV	GROA_HUMAN	Increases Expression	[25]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Decreases Expression	[25]
Complement C1s subcomponent (C1S)	OTCIZU2A	C1S_HUMAN	Increases Expression	[25]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Increases Expression	[25]
Interferon alpha-inducible protein 6 (IFI6)	OTWOOAM4	IFI6_HUMAN	Increases Expression	[25]
Polyunsaturated fatty acid 5-lipoxygenase (ALOX5)	OT7FOIK2	LOX5_HUMAN	Increases Expression	[25]
Protein BNIP5 (BNIP5)	OTSO8B61	BNIP5_HUMAN	Increases Expression	[25]
Thymosin beta-15A (TMSB15A)	OTSBWCES	TB15A_HUMAN	Decreases Expression	[25]
Serum amyloid A-1 protein (SAA1)	OTO2D8S0	SAA1_HUMAN	Increases Expression	[25]
Serum amyloid A-2 protein (SAA2)	OTYAVJWG	SAA2_HUMAN	Increases Expression	[25]
G antigen 4 (GAGE4)	OTPB5C0O	GAGE4_HUMAN	Decreases Expression	[25]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Increases Expression	[25]
Retinoic acid receptor alpha (RARA)	OT192V9V	RARA_HUMAN	Decreases Expression	[25]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[25]
Microsomal glutathione S-transferase 1 (MGST1)	OTGN1KVZ	MGST1_HUMAN	Decreases Expression	[25]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Increases Expression	[25]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Increases Expression	[25]
Microtubule-associated protein 2 (MAP2)	OT6UYT3X	MTAP2_HUMAN	Decreases Expression	[25]
DNA topoisomerase 2-alpha (TOP2A)	OT6LPS08	TOP2A_HUMAN	Decreases Expression	[25]
Cytochrome P450 2C9 (CYP2C9)	OTGLBN29	CP2C9_HUMAN	Increases Expression	[25]
Interleukin-7 (IL7)	OTT6YSKM	IL7_HUMAN	Decreases Expression	[25]
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Increases Expression	[25]
Cytochrome P450 4B1 (CYP4B1)	OTJP46CB	CP4B1_HUMAN	Increases Expression	[25]
Metallothionein-1G (MT1G)	OTAV1OCR	MT1G_HUMAN	Increases Expression	[25]
Tissue factor (F3)	OT3MSU3B	TF_HUMAN	Decreases Expression	[25]
HLA class I histocompatibility antigen, alpha chain E (HLA-E)	OTX1CTFB	HLAE_HUMAN	Increases Expression	[25]
HLA class II histocompatibility antigen, DR beta 4 chain (HLA-DRB4)	OTNXIHQU	DRB4_HUMAN	Increases Expression	[25]
Plastin-2 (LCP1)	OTK61F2A	PLSL_HUMAN	Increases Expression	[25]
CD59 glycoprotein (CD59)	OTSUMQDH	CD59_HUMAN	Increases Expression	[25]
Cathepsin E (CTSE)	OT4905MD	CATE_HUMAN	Increases Expression	[25]
L-selectin (SELL)	OT6RAJZR	LYAM1_HUMAN	Increases Expression	[25]
Interferon regulatory factor 2 (IRF2)	OTAZRUW3	IRF2_HUMAN	Increases Expression	[25]
Aldo-keto reductase family 1 member A1 (AKR1A1)	OTZT9NOW	AK1A1_HUMAN	Increases Expression	[25]
Interleukin-1 receptor type 1 (IL1R1)	OTTU8959	IL1R1_HUMAN	Increases Expression	[25]
Indoleamine 2,3-dioxygenase 1 (IDO1)	OT91DBN7	I23O1_HUMAN	Increases Expression	[25]
Protein C-ets-1 (ETS1)	OT4LVGDN	ETS1_HUMAN	Increases Expression	[25]
Protein C-ets-2 (ETS2)	OTPVHOZ7	ETS2_HUMAN	Decreases Expression	[25]
Aldo-keto reductase family 1 member B1 (AKR1B1)	OTRX72TH	ALDR_HUMAN	Increases Expression	[25]
Aminopeptidase N (ANPEP)	OTP3WYFD	AMPN_HUMAN	Increases Expression	[25]
Interferon gamma receptor 1 (IFNGR1)	OTCTQBWW	INGR1_HUMAN	Increases Expression	[25]
Prostatic acid phosphatase (ACP3)	OTSIM0YG	PPAP_HUMAN	Decreases Expression	[25]
V-type proton ATPase subunit B, kidney isoform (ATP6V1B1)	OT8FQ7MN	VATB1_HUMAN	Decreases Expression	[25]
Folate receptor alpha (FOLR1)	OT0QZ0H6	FOLR1_HUMAN	Decreases Expression	[25]
15-hydroxyprostaglandin dehydrogenase (HPGD)	OTYZI6JB	PGDH_HUMAN	Decreases Expression	[25]
NAD(P)H dehydrogenase 1 (NQO1)	OTZGGIVK	NQO1_HUMAN	Decreases Expression	[25]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Increases Expression	[25]
Carbonyl reductase 1 (CBR1)	OTQ3A541	CBR1_HUMAN	Decreases Expression	[25]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Increases Expression	[25]
SH2/SH3 adapter protein NCK1 (NCK1)	OTKYZ4OP	NCK1_HUMAN	Increases Expression	[25]
Histone H1.2 (H1-2)	OT0AVI4M	H12_HUMAN	Increases Expression	[25]
C-C motif chemokine 3-like 1 (CCL3L1)	OTQXCYB1	CL3L1_HUMAN	Increases Expression	[25]
Stathmin (STMN1)	OTDJ4RV0	STMN1_HUMAN	Decreases Expression	[25]
Atrial natriuretic peptide receptor 3 (NPR3)	OT6MQP3A	ANPRC_HUMAN	Decreases Expression	[25]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Increases Expression	[25]
T-complex protein 1 subunit alpha (TCP1)	OT1MGUX9	TCPA_HUMAN	Decreases Expression	[25]
Integrin beta-5 (ITGB5)	OT21MF51	ITB5_HUMAN	Decreases Expression	[25]
Early growth response protein 1 (EGR1)	OTCP6XGZ	EGR1_HUMAN	Decreases Expression	[25]
Syndecan-1 (SDC1)	OTWKRVZC	SDC1_HUMAN	Decreases Expression	[25]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4)	OTRFV19J	ATF4_HUMAN	Decreases Expression	[25]
Glutathione hydrolase 1 proenzyme (GGT1)	OTYDA1Z7	GGT1_HUMAN	Decreases Expression	[25]
C-X-C motif chemokine 2 (CXCL2)	OTEJCYMY	CXCL2_HUMAN	Increases Expression	[25]
Elafin (PI3)	OT47MTC3	ELAF_HUMAN	Increases Expression	[25]
Transcobalamin-1 (TCN1)	OTW6A49Y	TCO1_HUMAN	Increases Expression	[25]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[25]
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B)	OTDS2EAR	TNR1B_HUMAN	Increases Expression	[25]
Lamin-B1 (LMNB1)	OT100T3P	LMNB1_HUMAN	Decreases Expression	[25]
Cytochrome P450 3A5 (CYP3A5)	OTSXFBXB	CP3A5_HUMAN	Increases Expression	[25]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Increases Expression	[25]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)	OTVLI4DD	TNAP3_HUMAN	Increases Expression	[25]
Kit ligand (KITLG)	OTB9AVQ4	SCF_HUMAN	Decreases Expression	[25]
Protein-glutamine gamma-glutamyltransferase 2 (TGM2)	OT6MFOWF	TGM2_HUMAN	Increases Expression	[25]
Fibroblast growth factor receptor 4 (FGFR4)	OTRQERG2	FGFR4_HUMAN	Decreases Expression	[25]
Fibroblast growth factor receptor 3 (FGFR3)	OTSAXDIL	FGFR3_HUMAN	Decreases Expression	[25]
Ferrochelatase, mitochondrial (FECH)	OTDWEI6C	HEMH_HUMAN	Decreases Expression	[25]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Increases Expression	[25]
Tyrosine-protein kinase JAK1 (JAK1)	OT0X3D17	JAK1_HUMAN	Increases Expression	[25]
Receptor-type tyrosine-protein phosphatase gamma (PTPRG)	OT9N2WOF	PTPRG_HUMAN	Increases Expression	[25]
Interleukin-32 (IL32)	OT3FHZ81	IL32_HUMAN	Increases Expression	[25]
Cytochrome P450 3A7 (CYP3A7)	OTTCDHHM	CP3A7_HUMAN	Increases Expression	[25]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Decreases Expression	[25]
Tenascin (TNC)	OTK4FSHR	TENA_HUMAN	Increases Expression	[25]
Laminin subunit alpha-1 (LAMA1)	OTQZMP86	LAMA1_HUMAN	Decreases Expression	[25]
Cathepsin S (CTSS)	OT3PXIPM	CATS_HUMAN	Increases Expression	[25]
Tumor necrosis factor receptor superfamily member 5 (CD40)	OT5YU2XB	TNR5_HUMAN	Increases Expression	[25]
NF-kappa-B inhibitor alpha (NFKBIA)	OTFT924M	IKBA_HUMAN	Increases Expression	[25]
Interleukin-1 receptor type 2 (IL1R2)	OT0G7E35	IL1R2_HUMAN	Decreases Expression	[25]
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1)	OT5BZ1J9	P85A_HUMAN	Increases Expression	[25]
HLA class II histocompatibility antigen, DM beta chain (HLA-DMB)	OT17HGXJ	DMB_HUMAN	Increases Expression	[25]
Tropomodulin-1 (TMOD1)	OTTRYF9Y	TMOD1_HUMAN	Increases Expression	[25]
Protein ITPRID2 (ITPRID2)	OTO3JDX5	ITPI2_HUMAN	Decreases Expression	[25]
Alcohol dehydrogenase 6 (ADH6)	OTS7DYH9	ADH6_HUMAN	Decreases Expression	[25]
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1)	OTO7FJA9	DHI1_HUMAN	Increases Expression	[25]
Hematopoietic progenitor cell antigen CD34 (CD34)	OT1MOFLZ	CD34_HUMAN	Increases Expression	[25]
Gap junction beta-2 protein (GJB2)	OTBKLEYB	CXB2_HUMAN	Increases Expression	[25]
Protein S100-A2 (S100A2)	OTTGHJ1H	S10A2_HUMAN	Decreases Expression	[25]
Collagen alpha-5(IV) chain (COL4A5)	OTHG60RE	CO4A5_HUMAN	Decreases Expression	[25]
Caspase-1 (CASP1)	OTZ3YQFU	CASP1_HUMAN	Increases Expression	[25]
Serpin B3 (SERPINB3)	OTSR2UBI	SPB3_HUMAN	Increases Expression	[25]
Myristoylated alanine-rich C-kinase substrate (MARCKS)	OT7N056G	MARCS_HUMAN	Increases Expression	[25]
Phenazine biosynthesis-like domain-containing protein (PBLD)	OTI3A8RS	PBLD_HUMAN	Decreases Expression	[25]
HLA class I histocompatibility antigen, alpha chain F (HLA-F)	OT76CM19	HLAF_HUMAN	Increases Expression	[25]
Tyrosine-protein kinase receptor UFO (AXL)	OTKA2SUX	UFO_HUMAN	Decreases Expression	[25]
Somatostatin receptor type 1 (SSTR1)	OTFAGWO7	SSR1_HUMAN	Decreases Expression	[25]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (SRD5A2)	OTTG0NFD	S5A2_HUMAN	Increases Expression	[25]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Decreases Expression	[25]
Fibroblast growth factor 9 (FGF9)	OT2SKDGM	FGF9_HUMAN	Decreases Expression	[25]
Syndecan-4 (SDC4)	OTKUVUGZ	SDC4_HUMAN	Increases Expression	[25]
Guanylate-binding protein 2 (GBP2)	OTVU4G07	GBP2_HUMAN	Increases Expression	[25]
Cystathionine gamma-lyase (CTH)	OTC90LA0	CGL_HUMAN	Decreases Expression	[25]
MHC class II transactivator (CIITA)	OTRJNZFO	C2TA_HUMAN	Increases Expression	[25]
Protein S100-A3 (S100A3)	OTVIZJ2R	S10A3_HUMAN	Increases Expression	[25]
Dual specificity protein kinase TTK (TTK)	OTBY1Z5H	TTK_HUMAN	Decreases Expression	[25]
Syndecan-2 (SDC2)	OTEEHY1D	SDC2_HUMAN	Decreases Expression	[25]
Macrosialin (CD68)	OTOYEY3J	CD68_HUMAN	Increases Expression	[25]
Bifunctional epoxide hydrolase 2 (EPHX2)	OTPTRCNW	HYES_HUMAN	Decreases Expression	[25]
G protein-coupled receptor kinase 5 (GRK5)	OTJK79EK	GRK5_HUMAN	Increases Expression	[25]
Nitric oxide synthase, inducible (NOS2)	OTKKIOJ1	NOS2_HUMAN	Increases Expression	[25]
Small proline-rich protein 2A (SPRR2A)	OT62ZU6B	SPR2A_HUMAN	Increases Expression	[25]
Prostaglandin E2 receptor EP4 subtype (PTGER4)	OT2GBV06	PE2R4_HUMAN	Increases Expression	[25]
Cystathionine beta-synthase (CBS)	OT46FSKD	CBS_HUMAN	Decreases Expression	[25]
Serum amyloid A-4 protein (SAA4)	OTCE1WXO	SAA4_HUMAN	Increases Expression	[25]
Copper-transporting ATPase 2 (ATP7B)	OTPWLNCO	ATP7B_HUMAN	Decreases Expression	[25]
Bone morphogenetic protein receptor type-1A (BMPR1A)	OTQOA4ZH	BMR1A_HUMAN	Increases Expression	[25]
17-beta-hydroxysteroid dehydrogenase type 2 (HSD17B2)	OT3K7HY5	DHB2_HUMAN	Increases Expression	[25]
Collagen alpha-1(XVIII) chain (COL18A1)	OTJFUH6O	COIA1_HUMAN	Decreases Expression	[25]
Adenylyl cyclase-associated protein 2 (CAP2)	OTC1WFNO	CAP2_HUMAN	Decreases Expression	[25]
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)	OTQOUHVK	CEAM6_HUMAN	Increases Expression	[25]
Interferon alpha-inducible protein 27, mitochondrial (IFI27)	OTI2XGIT	IFI27_HUMAN	Increases Expression	[25]
Signal transducer and activator of transcription 3 (STAT3)	OTAAGKYZ	STAT3_HUMAN	Increases Expression	[25]
Extracellular calcium-sensing receptor (CASR)	OT2PEJDO	CASR_HUMAN	Decreases Expression	[25]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8)	OTOZTA1F	M3K8_HUMAN	Increases Expression	[25]
Tetraspanin-7 (TSPAN7)	OTE4DJ79	TSN7_HUMAN	Decreases Expression	[25]
Signal transducer and activator of transcription 1-alpha/beta (STAT1)	OTLMBUZ6	STAT1_HUMAN	Increases Expression	[25]
Signal transducer and activator of transcription 5A (STAT5A)	OTBSJGN3	STA5A_HUMAN	Increases Expression	[25]
Tyrosine-protein kinase FRK (FRK)	OTEKV1SC	FRK_HUMAN	Increases Expression	[25]
Cyclin-dependent kinase 4 inhibitor B (CDKN2B)	OTAG24N1	CDN2B_HUMAN	Increases Expression	[25]
C-X-C motif chemokine 5 (CXCL5)	OTZOUPCA	CXCL5_HUMAN	Increases Expression	[25]
Endothelin-converting enzyme 1 (ECE1)	OTPFHC6F	ECE1_HUMAN	Increases Expression	[25]
Excitatory amino acid transporter 1 (SLC1A3)	OTILR60R	EAA1_HUMAN	Increases Expression	[25]
ETS translocation variant 4 (ETV4)	OT8C98UZ	ETV4_HUMAN	Decreases Expression	[25]
Nicotinamide phosphoribosyltransferase (NAMPT)	OTVJR3GL	NAMPT_HUMAN	Increases Expression	[25]
Solute carrier family 15 member 1 (SLC15A1)	OT1P16B5	S15A1_HUMAN	Increases Expression	[25]
Rap1 GTPase-activating protein 1 (RAP1GAP)	OTC31ONQ	RPGP1_HUMAN	Decreases Expression	[25]
Secretin receptor (SCTR)	OTC80IMR	SCTR_HUMAN	Decreases Expression	[25]
Retinaldehyde dehydrogenase 3 (ALDH1A3)	OT1C9NKQ	AL1A3_HUMAN	Increases Expression	[25]
DNA-binding protein inhibitor ID-4 (ID4)	OTPMJ39I	ID4_HUMAN	Increases Expression	[25]
Sodium- and chloride-dependent creatine transporter 1 (SLC6A8)	OT88C8JA	SC6A8_HUMAN	Decreases Expression	[25]
ATP-sensitive inward rectifier potassium channel 1 (KCNJ1)	OTIXCRI6	KCNJ1_HUMAN	Decreases Expression	[25]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Decreases Expression	[25]
NADP-dependent malic enzyme (ME1)	OTSVEUQE	MAOX_HUMAN	Increases Expression	[25]
Transmembrane 4 L6 family member 4 (TM4SF4)	OTRI8EHN	T4S4_HUMAN	Decreases Expression	[25]
Tissue factor pathway inhibitor 2 (TFPI2)	OTZCRWOR	TFPI2_HUMAN	Increases Expression	[25]
Transcription factor SOX-2 (SOX2)	OTFAWCAU	SOX2_HUMAN	Increases Expression	[25]
Transcription factor SOX-9 (SOX9)	OTVDJFGN	SOX9_HUMAN	Decreases Expression	[25]
Lanosterol synthase (LSS)	OT9W2SFH	LSS_HUMAN	Increases Expression	[25]
Isocitrate dehydrogenase , mitochondrial (IDH2)	OTTQA4PB	IDHP_HUMAN	Decreases Expression	[25]
Natural resistance-associated macrophage protein 2 (SLC11A2)	OTMEUHE8	NRAM2_HUMAN	Increases Expression	[25]
Histone H3-like centromeric protein A (CENPA)	OT0NEJ4X	CENPA_HUMAN	Decreases Expression	[25]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Decreases Expression	[25]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Increases Expression	[25]
Amiloride-sensitive sodium channel subunit gamma (SCNN1G)	OTSJYQVQ	SCNNG_HUMAN	Increases Expression	[25]
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2)	OT714BUO	AL3A2_HUMAN	Decreases Expression	[25]
Glypican-3 (GPC3)	OTWS8WSW	GPC3_HUMAN	Decreases Expression	[25]
H(+)/Cl(-) exchange transporter 5 (CLCN5)	OT9YXZSO	CLCN5_HUMAN	Decreases Expression	[25]
Chloride channel protein ClC-Ka (CLCNKA)	OT7Q0RI9	CLCKA_HUMAN	Decreases Expression	[25]
Chloride channel protein ClC-Kb (CLCNKB)	OTMIG14Q	CLCKB_HUMAN	Decreases Expression	[25]
Hepatoma-derived growth factor (HDGF)	OT16PTBC	HDGF_HUMAN	Increases Expression	[25]
Caspase-5 (CASP5)	OT0F2THD	CASP5_HUMAN	Increases Expression	[25]
Serine/threonine-protein kinase Nek2 (NEK2)	OT1H27HO	NEK2_HUMAN	Decreases Expression	[25]
Cationic amino acid transporter 2 (SLC7A2)	OTAMWBVM	CTR2_HUMAN	Decreases Expression	[25]
Ephrin-B2 (EFNB2)	OT0DCUOM	EFNB2_HUMAN	Decreases Expression	[25]
Nuclear pore complex protein Nup98-Nup96 (NUP98)	OTNT12G2	NUP98_HUMAN	Decreases Expression	[25]
Diphosphomevalonate decarboxylase (MVD)	OTGEX4SR	MVD1_HUMAN	Increases Expression	[25]
Mitogen-activated protein kinase 10 (MAPK10)	OTC46VX1	MK10_HUMAN	Decreases Expression	[25]
Sodium/myo-inositol cotransporter (SLC5A3)	OT6FY2KA	SC5A3_HUMAN	Decreases Expression	[25]
Smoothelin (SMTN)	OT4R2TYK	SMTN_HUMAN	Decreases Expression	[25]
Ataxin-1 (ATXN1)	OTQF0HNR	ATX1_HUMAN	Increases Expression	[25]
Sodium/potassium-transporting ATPase subunit gamma (FXYD2)	OT97BX21	ATNG_HUMAN	Decreases Expression	[25]
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (PDE1A)	OTU7J3F7	PDE1A_HUMAN	Decreases Expression	[25]
Ephrin type-B receptor 3 (EPHB3)	OT4XD8O3	EPHB3_HUMAN	Decreases Expression	[25]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Increases Expression	[25]
GTP-binding protein GEM (GEM)	OT6SK8ZV	GEM_HUMAN	Decreases Expression	[25]
Cadherin-4 (CDH4)	OT8LH3HN	CADH4_HUMAN	Increases Expression	[25]
C-C motif chemokine 23 (CCL23)	OTE2DU0A	CCL23_HUMAN	Increases Expression	[25]
IgG receptor FcRn large subunit p51 (FCGRT)	OT4C0SRR	FCGRN_HUMAN	Decreases Expression	[25]
Integrin alpha-1 (ITGA1)	OTDITIST	ITA1_HUMAN	Increases Expression	[25]
AP-1 complex subunit sigma-2 (AP1S2)	OTZHJFYI	AP1S2_HUMAN	Increases Expression	[25]
ADP-ribosylation factor-like protein 4C (ARL4C)	OTQ3QNNU	ARL4C_HUMAN	Decreases Expression	[25]
Protein ripply3 (RIPPLY3)	OT1HK35I	DSCR6_HUMAN	Decreases Expression	[25]
Glucose-6-phosphate exchanger SLC37A1 (SLC37A1)	OTSYK97W	G6PT2_HUMAN	Increases Expression	[25]
Transmembrane protease serine 3 (TMPRSS3)	OT0GTO1Z	TMPS3_HUMAN	Increases Expression	[25]
Claudin-2 (CLDN2)	OTRF3D6Y	CLD2_HUMAN	Decreases Expression	[25]
Olfactory receptor 12D2 (OR12D2)	OTQZXHST	O12D2_HUMAN	Increases Expression	[25]
Histone H2B type 1-D (H2BC5)	OTXDTDHN	H2B1D_HUMAN	Increases Expression	[25]
Beta-defensin 1 (DEFB1)	OT5SV0E4	DEFB1_HUMAN	Increases Expression	[25]
Synaptosomal-associated protein 25 (SNAP25)	OTUIQ81Q	SNP25_HUMAN	Increases Expression	[25]
C-X-C chemokine receptor type 4 (CXCR4)	OTUFSBX2	CXCR4_HUMAN	Increases Expression	[25]
Ras-related protein Rap-1b (RAP1B)	OTHEIIMM	RAP1B_HUMAN	Increases Expression	[25]
Transforming growth factor beta-2 proprotein (TGFB2)	OTC0TXEP	TGFB2_HUMAN	Increases Expression	[25]
cAMP-dependent protein kinase inhibitor alpha (PKIA)	OT8M5GVO	IPKA_HUMAN	Decreases Expression	[25]
Estrogen-related receptor gamma (ESRRG)	OTC3A0KU	ERR3_HUMAN	Decreases Expression	[25]
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A)	OT6285L4	FKB1A_HUMAN	Increases Expression	[25]
Actin, gamma-enteric smooth muscle (ACTG2)	OTRDWUO0	ACTH_HUMAN	Decreases Expression	[25]
Contactin-associated protein 1 (CNTNAP1)	OT5Y03EU	CNTP1_HUMAN	Increases Expression	[25]
Iroquois-class homeodomain protein IRX-3 (IRX3)	OTLJ48FG	IRX3_HUMAN	Decreases Expression	[25]
Fractalkine (CX3CL1)	OTPLGI0E	X3CL1_HUMAN	Increases Expression	[25]
DENN domain-containing protein 2B (DENND2B)	OT7UH61B	DEN2B_HUMAN	Increases Expression	[25]
C-C motif chemokine 8 (CCL8)	OTCTWYN8	CCL8_HUMAN	Increases Expression	[25]
Neutrophil gelatinase-associated lipocalin (LCN2)	OTSB42BR	NGAL_HUMAN	Increases Expression	[25]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2)	OTHF4H9U	DHI2_HUMAN	Decreases Expression	[25]
Brain acid soluble protein 1 (BASP1)	OTF4VS5G	BASP1_HUMAN	Increases Expression	[25]
ADAMTS-like protein 3 (ADAMTSL3)	OTMC2WFG	ATL3_HUMAN	Decreases Expression	[25]
Mothers against decapentaplegic homolog 3 (SMAD3)	OTNA96MR	SMAD3_HUMAN	Increases Expression	[25]
Matrix-remodeling-associated protein 7 (MXRA7)	OTVQLYIY	MXRA7_HUMAN	Increases Expression	[25]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)	OTSFVC82	2ABB_HUMAN	Affects Expression	[25]
Nuclear factor NF-kappa-B p100 subunit (NFKB2)	OTS231V7	NFKB2_HUMAN	Increases Expression	[25]
Pregnancy-specific beta-1-glycoprotein 4 (PSG4)	OTCFNW3L	PSG4_HUMAN	Decreases Expression	[25]
CD83 antigen (CD83)	OT1V4WQF	CD83_HUMAN	Increases Expression	[25]
Transcription factor RelB (RELB)	OTU3QYEF	RELB_HUMAN	Increases Expression	[25]
Ankyrin-2 (ANK2)	OTWB4R1Y	ANK2_HUMAN	Decreases Expression	[25]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)	OTCO26FV	HMCS1_HUMAN	Increases Expression	[25]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Decreases Expression	[25]
Collagen alpha-3(IV) chain (COL4A3)	OT6SB8X5	CO4A3_HUMAN	Decreases Expression	[25]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Decreases Expression	[25]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Increases Expression	[25]
Interferon regulatory factor 8 (IRF8)	OT8YSNI4	IRF8_HUMAN	Decreases Expression	[25]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1)	OTF6OC66	GCNT1_HUMAN	Decreases Expression	[25]
Cyclic AMP-responsive element-binding protein 5 (CREB5)	OTJDUJPI	CREB5_HUMAN	Decreases Expression	[25]
Histone-lysine N-methyltransferase MECOM (MECOM)	OTP983W8	MECOM_HUMAN	Decreases Expression	[25]
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2)	OTRZH80H	TNAP2_HUMAN	Increases Expression	[25]
Peroxisome proliferator-activated receptor delta (PPARD)	OTI4WTOP	PPARD_HUMAN	Increases Expression	[25]
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)	OTQF5ZAK	PTH1R_HUMAN	Decreases Expression	[25]
Transducin-like enhancer protein 4 (TLE4)	OT4QEH6T	TLE4_HUMAN	Increases Expression	[25]
Regenerating islet-derived protein 3-alpha (REG3A)	OT0BVQRB	REG3A_HUMAN	Increases Expression	[25]
Lymphotoxin-beta (LTB)	OTUFS8CF	TNFC_HUMAN	Increases Expression	[25]
Transcription factor SOX-4 (SOX4)	OTSS40SS	SOX4_HUMAN	Decreases Expression	[25]
Collagen alpha-1(XVI) chain (COL16A1)	OTOWKUO2	COGA1_HUMAN	Increases Expression	[25]
Early activation antigen CD69 (CD69)	OTGJHSVP	CD69_HUMAN	Increases Expression	[25]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B)	OTOA8WU2	PDE4B_HUMAN	Decreases Expression	[25]
Amino acid transporter heavy chain SLC3A1 (SLC3A1)	OT56V01A	SLC31_HUMAN	Decreases Expression	[25]
Protein phosphatase 3 catalytic subunit alpha (PPP3CA)	OT58PUEN	PP2BA_HUMAN	Increases Expression	[25]
Epithelial discoidin domain-containing receptor 1 (DDR1)	OTYW1SH8	DDR1_HUMAN	Increases Expression	[25]
Testican-1 (SPOCK1)	OTLTDGK7	TICN1_HUMAN	Decreases Expression	[25]
Schlafen family member 5 (SLFN5)	OTT1AESL	SLFN5_HUMAN	Increases Expression	[25]
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (MGAT3)	OTXI5X4T	MGAT3_HUMAN	Increases Expression	[25]
Transmembrane protein 267 (TMEM267)	OTEAAVK7	TM267_HUMAN	Increases Expression	[25]
Cingulin-like protein 1 (CGNL1)	OTRE9DGT	CGNL1_HUMAN	Decreases Expression	[25]
Forkhead box protein O1 (FOXO1)	OTPJRB6D	FOXO1_HUMAN	Decreases Expression	[25]
Follistatin-related protein 1 (FSTL1)	OT6KEZUD	FSTL1_HUMAN	Increases Expression	[25]
Oviduct-specific glycoprotein (OVGP1)	OTL2W9M5	OVGP1_HUMAN	Increases Expression	[25]
Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)	OTESFZSO	PTN13_HUMAN	Decreases Expression	[25]
Filensin (BFSP1)	OTXZ3YIU	BFSP1_HUMAN	Decreases Expression	[25]
Protein AF1q (MLLT11)	OTG5RVHC	AF1Q_HUMAN	Decreases Expression	[25]
PDZK1-interacting protein 1 (PDZK1IP1)	OTWA6M5K	PDZ1I_HUMAN	Increases Expression	[25]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Decreases Expression	[25]
Probable ATP-dependent RNA helicase DDX10 (DDX10)	OTH48438	DDX10_HUMAN	Decreases Expression	[25]
Pappalysin-1 (PAPPA)	OTTTG9PG	PAPP1_HUMAN	Decreases Expression	[25]
Battenin (CLN3)	OTDDKT8R	CLN3_HUMAN	Increases Expression	[25]
Mammaglobin-A (SCGB2A2)	OTXBFHK8	SG2A2_HUMAN	Increases Expression	[25]
Urea transporter 1 (SLC14A1)	OTH7UUV0	UT1_HUMAN	Decreases Expression	[25]
Frizzled-5 (FZD5)	OTXFFY56	FZD5_HUMAN	Increases Expression	[25]
Interleukin-18 receptor 1 (IL18R1)	OT83XMPQ	IL18R_HUMAN	Increases Expression	[25]
Baculoviral IAP repeat-containing protein 3 (BIRC3)	OT3E95KB	BIRC3_HUMAN	Increases Expression	[25]
NGFI-A-binding protein 1 (NAB1)	OTEWHIZR	NAB1_HUMAN	Increases Expression	[25]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A)	OTGTAGCV	PPR1A_HUMAN	Decreases Expression	[25]
Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)	OTJ5XLVU	KCC2D_HUMAN	Decreases Expression	[25]
Cullin-4A (CUL4A)	OTTBV70J	CUL4A_HUMAN	Increases Expression	[25]
Solute carrier family 12 member 1 (SLC12A1)	OT6YSX0G	S12A1_HUMAN	Decreases Expression	[25]
Ras-related protein Rab-31 (RAB31)	OTMLXQZ0	RAB31_HUMAN	Increases Expression	[25]
Laminin subunit beta-3 (LAMB3)	OTFPU6W8	LAMB3_HUMAN	Increases Expression	[25]
Laminin subunit gamma-2 (LAMC2)	OTJMTM72	LAMC2_HUMAN	Increases Expression	[25]
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)	OTGM06VJ	IDI1_HUMAN	Increases Expression	[25]
Carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7)	OTKFDTZY	CEAM7_HUMAN	Increases Expression	[25]
Cyclic nucleotide-gated cation channel beta-1 (CNGB1)	OTA5DE38	CNGB1_HUMAN	Increases Expression	[25]
Bile acid-CoA:amino acid N-acyltransferase (BAAT)	OTTMB3JY	BAAT_HUMAN	Increases Expression	[25]
Collagen alpha-2(IX) chain (COL9A2)	OT1ZBDBV	CO9A2_HUMAN	Increases Expression	[25]
Nidogen-2 (NID2)	OTHC33FF	NID2_HUMAN	Increases Expression	[25]
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE)	OT5VYOSM	IKKE_HUMAN	Increases Expression	[25]
Four and a half LIM domains protein 2 (FHL2)	OT0OAYWT	FHL2_HUMAN	Decreases Expression	[25]
Interleukin-27 subunit beta (EBI3)	OT0LF3D7	IL27B_HUMAN	Increases Expression	[25]
Fibroleukin (FGL2)	OT8M3H72	FGL2_HUMAN	Decreases Expression	[25]
Glutathione hydrolase light chain 2 (GGTLC2)	OT003Y7X	GGTL2_HUMAN	Decreases Expression	[25]
Growth factor receptor-bound protein 14 (GRB14)	OTFET2YM	GRB14_HUMAN	Decreases Expression	[25]
Transcription factor HES-1 (HES1)	OT8P19W2	HES1_HUMAN	Decreases Expression	[25]
Fibroblast growth factor-binding protein 1 (FGFBP1)	OTP4BSCH	FGFP1_HUMAN	Increases Expression	[25]
Keratin, type II cuticular Hb1 (KRT81)	OTMKIK2S	KRT81_HUMAN	Decreases Expression	[25]
DNA replication licensing factor MCM6 (MCM6)	OTKLIAWT	MCM6_HUMAN	Decreases Expression	[25]
Interleukin-13 receptor subunit alpha-2 (IL13RA2)	OTPC2G0X	I13R2_HUMAN	Increases Expression	[25]
Maternal embryonic leucine zipper kinase (MELK)	OTEY2UQA	MELK_HUMAN	Decreases Expression	[25]
Transmembrane glycoprotein NMB (GPNMB)	OTB7KQKV	GPNMB_HUMAN	Decreases Expression	[25]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Decreases Expression	[25]
TNFAIP3-interacting protein 1 (TNIP1)	OTRAOTEW	TNIP1_HUMAN	Increases Expression	[25]
Astrocytic phosphoprotein PEA-15 (PEA15)	OTKCKTSX	PEA15_HUMAN	Increases Expression	[25]
Phosphoglucomutase-like protein 5 (PGM5)	OTEAS7OC	PGM5_HUMAN	Decreases Expression	[25]
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP)	OTSMGKXQ	EBP_HUMAN	Increases Expression	[25]
Platelet-derived growth factor receptor-like protein (PDGFRL)	OTJPRECT	PGFRL_HUMAN	Increases Expression	[25]
Elongin-B (ELOB)	OTZ3X84T	ELOB_HUMAN	Decreases Expression	[25]
Disks large-associated protein 5 (DLGAP5)	OTWCN39U	DLGP5_HUMAN	Decreases Expression	[25]
Transcriptional enhancer factor TEF-4 (TEAD2)	OTM8YMYT	TEAD2_HUMAN	Decreases Expression	[25]
Pachytene checkpoint protein 2 homolog (TRIP13)	OTFM3TI9	PCH2_HUMAN	Decreases Expression	[25]
TSC22 domain family protein 1 (TSC22D1)	OTN4GFWD	T22D1_HUMAN	Increases Expression	[25]
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL)	OTK3EJFD	NSDHL_HUMAN	Increases Expression	[25]
Chitinase-3-like protein 2 (CHI3L2)	OT26R3HQ	CH3L2_HUMAN	Increases Expression	[25]
Methylsterol monooxygenase 1 (MSMO1)	OTKV62RZ	MSMO1_HUMAN	Increases Expression	[25]
Solute carrier family 15 member 2 (SLC15A2)	OTDV7YES	S15A2_HUMAN	Decreases Expression	[25]
Laminin subunit alpha-4 (LAMA4)	OTHI7TA0	LAMA4_HUMAN	Decreases Expression	[25]
Cysteine and glycine-rich protein 2 (CSRP2)	OT4SW0HI	CSRP2_HUMAN	Decreases Expression	[25]
Hepatic leukemia factor (HLF)	OTTRK9XN	HLF_HUMAN	Decreases Expression	[25]
Extracellular matrix protein 1 (ECM1)	OT1K65VW	ECM1_HUMAN	Increases Expression	[25]
BDNF/NT-3 growth factors receptor (NTRK2)	OTD557PU	NTRK2_HUMAN	Increases Expression	[25]
MAP kinase-activated protein kinase 3 (MAPKAPK3)	OT7IWJNI	MAPK3_HUMAN	Decreases Expression	[25]
kinase isozyme 4, mitochondrial (PDK4)	OTCMHMBZ	PDK4_HUMAN	Decreases Expression	[25]
Cyclin-dependent kinase inhibitor 3 (CDKN3)	OTBE3H07	CDKN3_HUMAN	Decreases Expression	[25]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[25]
Dual specificity protein phosphatase 5 (DUSP5)	OTH96RA7	DUS5_HUMAN	Decreases Expression	[25]
Kynureninase (KYNU)	OTINL2RE	KYNU_HUMAN	Increases Expression	[25]
Glutaminyl-peptide cyclotransferase (QPCT)	OT0TSHP4	QPCT_HUMAN	Increases Expression	[25]
Histone H2A type 2-C (H2AC20)	OTEIVLM1	H2A2C_HUMAN	Increases Expression	[25]
Histone H2B type 2-E (H2BC21)	OT0FDCUC	H2B2E_HUMAN	Increases Expression	[25]
Dual specificity protein phosphatase 6 (DUSP6)	OT4H6RKW	DUS6_HUMAN	Decreases Expression	[25]
Lanosterol 14-alpha demethylase (CYP51A1)	OTAYHG9C	CP51A_HUMAN	Increases Expression	[25]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)	OTQYEXL2	F264_HUMAN	Increases Expression	[25]
Tumor protein D53 (TPD52L1)	OTSA6U0I	TPD53_HUMAN	Decreases Expression	[25]
Izumo sperm-egg fusion protein 4 (IZUMO4)	OTA2C7K8	IZUM4_HUMAN	Increases Expression	[25]
Transmembrane protein 132A (TMEM132A)	OTNUI7O1	T132A_HUMAN	Increases Expression	[25]
Leucine-rich repeat-containing protein 26 (LRRC26)	OTXEFL76	LRC26_HUMAN	Decreases Expression	[25]
Leucine-rich repeat-containing protein 75B (LRRC75B)	OTAHOBSS	LR75B_HUMAN	Decreases Expression	[25]
HLA class II histocompatibility antigen, DR beta 5 chain (HLA-DRB5)	OTUX5TWM	DRB5_HUMAN	Increases Expression	[25]
Tyrosine-protein phosphatase non-receptor type 20 (PTPN20)	OTX9DXM6	PTN20_HUMAN	Increases Expression	[25]
Transmembrane protein 52B (TMEM52B)	OTOC70IF	TM52B_HUMAN	Decreases Expression	[25]
Filamin A-interacting protein 1-like (FILIP1L)	OTPY8IMS	FIL1L_HUMAN	Decreases Expression	[25]
Centrosomal protein of 55 kDa (CEP55)	OTGSG2PA	CEP55_HUMAN	Decreases Expression	[25]
Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3)	OT0AE1IV	ACSM3_HUMAN	Decreases Expression	[25]
Phospholipase A1 member A (PLA1A)	OT2IXYNX	PLA1A_HUMAN	Increases Expression	[25]
Borealin (CDCA8)	OT17D55D	BOREA_HUMAN	Decreases Expression	[25]
Ankyrin repeat domain-containing protein SOWAHC (SOWAHC)	OTI86ECP	SWAHC_HUMAN	Decreases Expression	[25]
Protein LBH (LBH)	OT87AT1X	LBH_HUMAN	Increases Expression	[25]
Beta-actin-like protein 2 (ACTBL2)	OTD6B81U	ACTBL_HUMAN	Increases Expression	[25]
Sigma intracellular receptor 2 (TMEM97)	OTH76ZWK	SGMR2_HUMAN	Increases Expression	[25]
Torsin-2A (TOR2A)	OT1EGCDU	TOR2A_HUMAN	Decreases Expression	[25]
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)	OTLS7C99	LRRK2_HUMAN	Decreases Expression	[25]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1)	OTGFK4MH	NHRF3_HUMAN	Decreases Expression	[25]
Adhesion G-protein coupled receptor F1 (ADGRF1)	OTRAOBYH	AGRF1_HUMAN	Increases Expression	[25]
Arginine vasopressin-induced protein 1 (AVPI1)	OTXSBR60	AVPI1_HUMAN	Decreases Expression	[25]
DEP domain-containing protein 1A (DEPDC1)	OT0JWE1B	DEP1A_HUMAN	Decreases Expression	[25]
Bcl-2-like protein 15 (BCL2L15)	OTD943W0	B2L15_HUMAN	Increases Expression	[25]
Intermediate filament family orphan 2 (IFFO2)	OT34XWYM	IFFO2_HUMAN	Increases Expression	[25]
Uncharacterized protein C1orf53 (C1ORF53)	OTQTOA4D	CA053_HUMAN	Decreases Expression	[25]
Immediate early response gene 5 protein (IER5)	OTJPTXMD	IER5_HUMAN	Increases Expression	[25]
Ankyrin repeat domain-containing protein 22 (ANKRD22)	OT6CRQ67	ANR22_HUMAN	Increases Expression	[25]
Nucleoredoxin-like protein 2 (NXNL2)	OT950KYC	NXNL2_HUMAN	Decreases Expression	[25]
ALS2 C-terminal-like protein (ALS2CL)	OT8RY7TZ	AL2CL_HUMAN	Increases Expression	[25]
Meteorin-like protein (METRNL)	OTB0DDL0	METRL_HUMAN	Decreases Expression	[25]
Cytosolic phospholipase A2 zeta (PLA2G4F)	OT8MUO5U	PA24F_HUMAN	Decreases Expression	[25]
Histone H2A type 2-A (H2AC18)	OTCE5JC7	H2A2A_HUMAN	Increases Expression	[25]
Isthmin-2 (ISM2)	OT4K7KON	ISM2_HUMAN	Decreases Expression	[25]
Uncharacterized protein KIAA0930 (KIAA0930)	OTVJ73LN	K0930_HUMAN	Decreases Expression	[25]
Aspartate beta-hydroxylase domain-containing protein 2 (ASPHD2)	OTKELV1D	ASPH2_HUMAN	Decreases Expression	[25]
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPEPLD)	OTJI1XF3	NAPEP_HUMAN	Increases Expression	[25]
Keratin, type II cytoskeletal 80 (KRT80)	OTAU54U3	K2C80_HUMAN	Decreases Expression	[25]
Calpain-13 (CAPN13)	OTK6PQFZ	CAN13_HUMAN	Increases Expression	[25]
Teneurin-4 (TENM4)	OT91K3FC	TEN4_HUMAN	Increases Expression	[25]
RPA-related protein RADX (RADX)	OTKV8BMJ	RADX_HUMAN	Decreases Expression	[25]
TMF-regulated nuclear protein 1 (TRNP1)	OTYYV8LN	TRNP1_HUMAN	Decreases Expression	[25]
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24)	OT3ZNGEL	SCMC1_HUMAN	Increases Expression	[25]
Cdc42 effector protein 5 (CDC42EP5)	OTQQDUCD	BORG3_HUMAN	Increases Expression	[25]
LLGL scribble cell polarity complex component 2 (LLGL2)	OTU8ZDC4	L2GL2_HUMAN	Increases Expression	[25]
Protein LEG1 homolog (C6ORF58)	OTT2T3DU	LEG1H_HUMAN	Increases Expression	[25]
Protein FAM171B (FAM171B)	OT4DJHCM	F171B_HUMAN	Decreases Expression	[25]
Polypeptide N-acetylgalactosaminyltransferase 18 (GALNT18)	OTKIIELC	GLT18_HUMAN	Increases Expression	[25]
Transmembrane protein 154 (TMEM154)	OTEAFLJE	TM154_HUMAN	Decreases Expression	[25]
Alpha/beta hydrolase domain-containing protein 17C (ABHD17C)	OTB1MTOI	AB17C_HUMAN	Decreases Expression	[25]
Iodotyrosine deiodinase 1 (IYD)	OT8BQWTE	IYD1_HUMAN	Decreases Expression	[25]
Kv channel-interacting protein 4 (KCNIP4)	OTB1BS0X	KCIP4_HUMAN	Decreases Expression	[25]
Inactive rhomboid protein 2 (RHBDF2)	OT2FHXQA	RHDF2_HUMAN	Increases Expression	[25]
SHC-transforming protein 4 (SHC4)	OTQ0H76H	SHC4_HUMAN	Decreases Expression	[25]
Actin remodeling regulator NHS (NHS)	OTKE8QAT	NHS_HUMAN	Decreases Expression	[25]
DBH-like monooxygenase protein 1 (MOXD1)	OTUMCWRN	MOXD1_HUMAN	Increases Expression	[25]
Protein O-glucosyltransferase 2 (POGLUT2)	OT5G79NO	PLGT2_HUMAN	Decreases Expression	[25]
Prostate androgen-regulated mucin-like protein 1 (PARM1)	OTDNK7EX	PARM1_HUMAN	Increases Expression	[25]
Dehydrogenase/reductase SDR family member 11 (DHRS11)	OTU3J0ZL	DHR11_HUMAN	Decreases Expression	[25]
Glycerophosphocholine cholinephosphodiesterase ENPP6 (ENPP6)	OT8QPRVJ	ENPP6_HUMAN	Increases Expression	[25]
Olfactomedin-4 (OLFM4)	OTELHN9L	OLFM4_HUMAN	Increases Expression	[25]
Transmembrane channel-like protein 5 (TMC5)	OTO5D86M	TMC5_HUMAN	Increases Expression	[25]
Sclerostin domain-containing protein 1 (SOSTDC1)	OTAKDNSM	SOSD1_HUMAN	Increases Expression	[25]
Solute carrier organic anion transporter family member 4C1 (SLCO4C1)	OTVILUUN	SO4C1_HUMAN	Decreases Expression	[25]
Pleckstrin homology domain-containing family G member 7 (PLEKHG7)	OTMVTCCR	PKHG7_HUMAN	Increases Expression	[25]
RNA-binding protein with multiple splicing 2 (RBPMS2)	OTY24L1F	RBPS2_HUMAN	Decreases Expression	[25]
Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1)	OTMW1B47	BCAP_HUMAN	Increases Expression	[25]
Vesicle transport protein GOT1A (GOLT1A)	OTY8H2OF	GOT1A_HUMAN	Decreases Expression	[25]
Syntaxin-binding protein 4 (STXBP4)	OT4BXRNV	STXB4_HUMAN	Decreases Expression	[25]
Regulator of hemoglobinization and erythroid cell expansion protein (RHEX)	OTAM5C0G	RHEX_HUMAN	Increases Expression	[25]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2)	OTYT1J6J	PREX2_HUMAN	Increases Expression	[25]
Cystin-1 (CYS1)	OTUXN7CO	CYS1_HUMAN	Decreases Expression	[25]
Protein phosphatase Slingshot homolog 2 (SSH2)	OT8NCK82	SSH2_HUMAN	Decreases Expression	[25]
BEN domain-containing protein 5 (BEND5)	OT6J6LY3	BEND5_HUMAN	Decreases Expression	[25]
Fc receptor-like A (FCRLA)	OT6MK4M1	FCRLA_HUMAN	Increases Expression	[25]
Protein MCM10 homolog (MCM10)	OTV0O3JN	MCM10_HUMAN	Decreases Expression	[25]
Synaptotagmin-13 (SYT13)	OTG94RJ4	SYT13_HUMAN	Decreases Expression	[25]
Equilibrative nucleoside transporter 4 (SLC29A4)	OTWTZXMX	S29A4_HUMAN	Decreases Expression	[25]
Monocarboxylate transporter 14 (SLC16A14)	OTUGDEUV	MOT14_HUMAN	Decreases Expression	[25]
Protein mono-ADP-ribosyltransferase TIPARP (TIPARP)	OTZ4BG4B	PARPT_HUMAN	Increases Expression	[25]
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 (SLC46A3)	OTEMDLPS	S46A3_HUMAN	Increases Expression	[25]
E3 ubiquitin-protein ligase RNF144B (RNF144B)	OTN7FCDE	R144B_HUMAN	Increases Expression	[25]
Protein ADM2 (ADM2)	OTJVN41C	ADM2_HUMAN	Decreases Expression	[25]
Rho GTPase-activating protein 22 (ARHGAP22)	OTXUQEFL	RHG22_HUMAN	Increases Expression	[25]
Cytoplasmic polyadenylation element-binding protein 2 (CPEB2)	OTKES4YR	CPEB2_HUMAN	Decreases Expression	[25]
Probable G-protein coupled receptor 141 (GPR141)	OTJ8WSSW	GP141_HUMAN	Increases Expression	[25]
Target of Nesh-SH3 (ABI3BP)	OTW8DN50	TARSH_HUMAN	Decreases Expression	[25]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1)	OTKCR5XL	CK2N1_HUMAN	Decreases Expression	[25]
Stearoyl-CoA desaturase 5 (SCD5)	OTSSUQ3Z	SCD5_HUMAN	Decreases Expression	[25]
Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10)	OTZ6FDOL	GLT10_HUMAN	Decreases Expression	[25]
Alpha-protein kinase 2 (ALPK2)	OTWZZDQ9	ALPK2_HUMAN	Increases Expression	[25]
Basic immunoglobulin-like variable motif-containing protein (BIVM)	OTQEJWSA	BIVM_HUMAN	Decreases Expression	[25]
Suppressor APC domain-containing protein 2 (SAPCD2)	OTXS0EXM	SAPC2_HUMAN	Decreases Expression	[25]
E3 ubiquitin-protein ligase MARCHF3 (MARCHF3)	OT89V4N5	MARH3_HUMAN	Increases Expression	[25]
Glucosylceramide transporter ABCA12 (ABCA12)	OTKH9YQZ	ABCAC_HUMAN	Increases Expression	[25]
Pleckstrin homology-like domain family B member 1 (PHLDB1)	OTIRCB6I	PHLB1_HUMAN	Decreases Expression	[25]
Four-jointed box protein 1 (FJX1)	OT8SVTSS	FJX1_HUMAN	Decreases Expression	[25]
Ran-binding protein 3-like (RANBP3L)	OTKOCHVJ	RNB3L_HUMAN	Decreases Expression	[25]
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (SGMS1)	OTZQE7PW	SMS1_HUMAN	Increases Expression	[25]
Transmembrane protein adipocyte-associated 1 (TPRA1)	OTL61503	TPRA1_HUMAN	Increases Expression	[25]
Proline and serine-rich protein 2 (PROSER2)	OT1SX3LS	PRSR2_HUMAN	Increases Expression	[25]
Stimulator of interferon genes protein (STING1)	OTDAP4G0	STING_HUMAN	Increases Expression	[25]
Protein FAM72B (FAM72B)	OT6AOG64	FA72B_HUMAN	Increases Expression	[25]
Copine-8 (CPNE8)	OTO6U97G	CPNE8_HUMAN	Decreases Expression	[25]
Complement C1q-like protein 4 (C1QL4)	OT9L6DLK	C1QL4_HUMAN	Decreases Expression	[25]
Calcium/calmodulin-dependent protein kinase type 1D (CAMK1D)	OTU24HAU	KCC1D_HUMAN	Increases Expression	[25]
Epidermal growth factor-like protein 6 (EGFL6)	OT331X59	EGFL6_HUMAN	Decreases Expression	[25]
Leucine rich adaptor protein 1-like (LURAP1L)	OTSJ29M5	LUR1L_HUMAN	Decreases Expression	[25]
Pleckstrin homology domain-containing family H member 2 (PLEKHH2)	OT3TK3NN	PKHH2_HUMAN	Decreases Expression	[25]
Protein AHNAK2 (AHNAK2)	OTD2X4BX	AHNK2_HUMAN	Decreases Expression	[25]
Formin-like protein 3 (FMNL3)	OTRP8R4W	FMNL3_HUMAN	Increases Expression	[25]
Nostrin (NOSTRIN)	OT0LDSGS	NOSTN_HUMAN	Decreases Expression	[25]
Neuron navigator 2 (NAV2)	OTGAOL01	NAV2_HUMAN	Decreases Expression	[25]
Prolyl 3-hydroxylase 2 (P3H2)	OTY84H6U	P3H2_HUMAN	Decreases Expression	[25]
SLIT and NTRK-like protein 4 (SLITRK4)	OTSCN5AM	SLIK4_HUMAN	Decreases Expression	[25]
Choline transporter-like protein 2 (SLC44A2)	OT11T33C	CTL2_HUMAN	Decreases Expression	[25]
Sphingosine-1-phosphate phosphatase 2 (SGPP2)	OTIDIJCR	SGPP2_HUMAN	Increases Expression	[25]
SMC5-SMC6 complex localization factor protein 2 (SLF2)	OTP8V0HC	SLF2_HUMAN	Decreases Expression	[25]
Uncharacterized protein C4orf19 (C4ORF19)	OTJMU7N6	CD019_HUMAN	Increases Expression	[25]
Nucleotidyltransferase MB21D2 (MB21D2)	OT5C4VVU	M21D2_HUMAN	Increases Expression	[25]
Voltage-dependent calcium channel subunit alpha-2/delta-3 (CACNA2D3)	OTEH9HGE	CA2D3_HUMAN	Increases Expression	[25]
Abnormal spindle-like microcephaly-associated protein (ASPM)	OTKXQMNA	ASPM_HUMAN	Decreases Expression	[25]
Dermatan-sulfate epimerase-like protein (DSEL)	OTVNQD3I	DSEL_HUMAN	Decreases Expression	[25]
Retinol dehydrogenase 10 (RDH10)	OTL9FSGF	RDH10_HUMAN	Increases Expression	[25]
Leucine-rich repeat LGI family member 2 (LGI2)	OTFJ2ZSG	LGI2_HUMAN	Decreases Expression	[25]
Neuroligin-4, X-linked (NLGN4X)	OTDJGBK8	NLGNX_HUMAN	Increases Expression	[25]
Nuclear pore complex protein Nup93 (NUP93)	OT4J2VAL	NUP93_HUMAN	Increases Expression	[25]
Rho GTPase-activating protein 24 (ARHGAP24)	OTCQCEZS	RHG24_HUMAN	Decreases Expression	[25]
Ly6/PLAUR domain-containing protein 1 (LYPD1)	OT0HSGML	LYPD1_HUMAN	Increases Expression	[25]
Lysoplasmalogenase TMEM86A (TMEM86A)	OTYJ4X3D	TM86A_HUMAN	Decreases Expression	[25]
Protein FAM43A (FAM43A)	OT5RPQRE	FA43A_HUMAN	Decreases Expression	[25]
Maturin (MTURN)	OTEBJNVG	MTURN_HUMAN	Decreases Expression	[25]
Inactive serine protease 35 (PRSS35)	OT09H6WH	PRS35_HUMAN	Increases Expression	[25]
Polypeptide N-acetylgalactosaminyltransferase 16 (GALNT16)	OTUBTPGE	GLT16_HUMAN	Decreases Expression	[25]
Major facilitator superfamily domain-containing protein 4A (MFSD4A)	OTUO018X	MFD4A_HUMAN	Decreases Expression	[25]
Protein limb expression 1 homolog (LIX1)	OT1CPNCC	LIX1_HUMAN	Decreases Expression	[25]
Probable hydrolase PNKD (PNKD)	OT6G9UXN	PNKD_HUMAN	Increases Expression	[25]
ADP-ribosylation factor-like protein 14 (ARL14)	OTE4MKOZ	ARL14_HUMAN	Decreases Expression	[25]
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (PIP4P2)	OT8OVB6R	PP4P2_HUMAN	Decreases Expression	[25]
Tetratricopeptide repeat protein 39C (TTC39C)	OTKKI81C	TT39C_HUMAN	Increases Expression	[25]
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (AADAT)	OTO68C3Y	AADAT_HUMAN	Decreases Expression	[25]
Protocadherin-20 (PCDH20)	OTFSNRXK	PCD20_HUMAN	Decreases Expression	[25]
Inactive phospholipase D5 (PLD5)	OTEVPYNY	PLD5_HUMAN	Increases Expression	[25]
Tetratricopeptide repeat protein 29 (TTC29)	OT37KCUL	TTC29_HUMAN	Increases Expression	[25]
Proprotein convertase subtilisin/kexin type 9 (PCSK9)	OTI0DU9Y	PCSK9_HUMAN	Increases Expression	[25]
Kinetochore protein Spc24 (SPC24)	OT1HVYV4	SPC24_HUMAN	Decreases Expression	[25]
Carbohydrate sulfotransferase 4 (CHST4)	OTESMIW5	CHST4_HUMAN	Increases Expression	[25]
Arrestin domain-containing protein 4 (ARRDC4)	OTINJ0FX	ARRD4_HUMAN	Increases Expression	[25]
C2 calcium-dependent domain-containing protein 4A (C2CD4A)	OTUKXHNG	C2C4A_HUMAN	Increases Expression	[25]
Polypeptide N-acetylgalactosaminyltransferase 11 (GALNT11)	OTANT9E6	GLT11_HUMAN	Decreases Expression	[25]
Uncharacterized protein C7orf57 (C7ORF57)	OTMAAJ4O	CG057_HUMAN	Decreases Expression	[25]
Neuron navigator 1 (NAV1)	OT667KTL	NAV1_HUMAN	Decreases Expression	[25]
RalBP1-associated Eps domain-containing protein 2 (REPS2)	OTSE3TRP	REPS2_HUMAN	Increases Expression	[25]
Retinoic acid-induced protein 3 (GPRC5A)	OTPOCWR7	RAI3_HUMAN	Decreases Expression	[25]
Delta and Notch-like epidermal growth factor-related receptor (DNER)	OT2GH2E5	DNER_HUMAN	Increases Expression	[25]
Speedy protein E1 (SPDYE1)	OTQOYX6U	SPDE1_HUMAN	Increases Expression	[25]
Olfactory receptor 8H1 (OR8H1)	OTXUR9OR	OR8H1_HUMAN	Increases Expression	[25]
Olfactory receptor 4K15 (OR4K15)	OT085629	OR4KF_HUMAN	Increases Expression	[25]
Nuclear receptor coactivator 7 (NCOA7)	OT2CNBOG	NCOA7_HUMAN	Increases Expression	[25]
Ly6/PLAUR domain-containing protein 6B (LYPD6B)	OTBCOEGI	LPD6B_HUMAN	Increases Expression	[25]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Decreases Expression	[25]
Prostamide/prostaglandin F synthase (PRXL2B)	OTY5G543	PXL2B_HUMAN	Increases Expression	[25]
TBC1 domain family member 16 (TBC1D16)	OTPR3C6A	TBC16_HUMAN	Increases Expression	[25]
Cytoplasmic dynein 2 light intermediate chain 1 (DYNC2LI1)	OT1X5YGJ	DC2L1_HUMAN	Decreases Expression	[25]
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD)	OTPSXPSF	ACMSD_HUMAN	Decreases Expression	[25]
Pantothenate kinase 1 (PANK1)	OT2CZVRT	PANK1_HUMAN	Decreases Expression	[25]
Membrane progestin receptor beta (PAQR8)	OTGZ8W9F	PAQR8_HUMAN	Increases Expression	[25]
Monocarboxylate transporter 10 (SLC16A10)	OTH70529	MOT10_HUMAN	Increases Expression	[25]
Cytosolic arginine sensor for mTORC1 subunit 1 (CASTOR1)	OTYIH7WK	CAST1_HUMAN	Increases Expression	[25]
Serine/threonine-protein kinase 32A (STK32A)	OTONYLYO	ST32A_HUMAN	Decreases Expression	[25]
Protein prune homolog 2 (PRUNE2)	OTGW2974	PRUN2_HUMAN	Increases Expression	[25]
Transmembrane protein 171 (TMEM171)	OTJPHOWW	TM171_HUMAN	Increases Expression	[25]
Adhesion G-protein coupled receptor V1 (ADGRV1)	OTLVXHHP	AGRV1_HUMAN	Increases Expression	[25]
Voltage-dependent calcium channel gamma-like subunit (TMEM37)	OT317PEL	CCGL_HUMAN	Decreases Expression	[25]
Radial spoke head 1 homolog (RSPH1)	OT3MR73R	RSPH1_HUMAN	Increases Expression	[25]
Transcription factor AP-2-beta (TFAP2B)	OTR1T8E9	AP2B_HUMAN	Decreases Expression	[25]
StAR-related lipid transfer protein 8 (STARD8)	OTY9IAKW	STAR8_HUMAN	Decreases Expression	[25]
Tetratricopeptide repeat protein 9A (TTC9)	OTL29A51	TTC9A_HUMAN	Increases Expression	[25]
Rho-related GTP-binding protein Rho6 (RND1)	OTOC223Z	RND1_HUMAN	Increases Expression	[25]
Serine protease HTRA1 (HTRA1)	OTR8ACBF	HTRA1_HUMAN	Decreases Expression	[25]
Type II iodothyronine deiodinase (DIO2)	OTGPNSLH	IOD2_HUMAN	Decreases Expression	[25]
Neuronal cell adhesion molecule (NRCAM)	OT80HHQ2	NRCAM_HUMAN	Increases Expression	[25]
Kallikrein-6 (KLK6)	OTIEA234	KLK6_HUMAN	Decreases Expression	[25]
Forkhead box protein J1 (FOXJ1)	OT7LLBZ7	FOXJ1_HUMAN	Decreases Expression	[25]
Tumor necrosis factor receptor superfamily member 14 (TNFRSF14)	OTB82PFO	TNR14_HUMAN	Increases Expression	[25]
Solute carrier organic anion transporter family member 2A1 (SLCO2A1)	OT3062CA	SO2A1_HUMAN	Increases Expression	[25]
Histone H2A type 1-C (H2AC6)	OTF3YK7V	H2A1C_HUMAN	Increases Expression	[25]
Homogentisate 1,2-dioxygenase (HGD)	OTTKLQOO	HGD_HUMAN	Decreases Expression	[25]
Myocardin-related transcription factor A (MRTFA)	OTCVXASM	MRTFA_HUMAN	Increases Expression	[25]
Terminal nucleotidyltransferase 5B (TENT5B)	OTO2P28B	TET5B_HUMAN	Decreases Expression	[25]
Ras-related and estrogen-regulated growth inhibitor (RERG)	OTF6MMLV	RERG_HUMAN	Decreases Expression	[25]
Transmembrane protein 125 (TMEM125)	OTWF8MC1	TM125_HUMAN	Decreases Expression	[25]
Mitochondrial calcium uniporter regulator 1 (MCUR1)	OTSL49SR	MCUR1_HUMAN	Increases Expression	[25]
Arrestin domain-containing protein 3 (ARRDC3)	OTAKW7R9	ARRD3_HUMAN	Increases Expression	[25]
Lipid droplet assembly factor 1 (LDAF1)	OTYDQ1QM	LDAF1_HUMAN	Increases Expression	[25]
Solute carrier organic anion transporter family member 4A1 (SLCO4A1)	OT3J1G7H	SO4A1_HUMAN	Increases Expression	[25]
Calcineurin B homologous protein 3 (TESC)	OTI8C76M	CHP3_HUMAN	Decreases Expression	[25]
Dedicator of cytokinesis protein 10 (DOCK10)	OTI3MBLV	DOC10_HUMAN	Increases Expression	[25]
TRAF-interacting protein with FHA domain-containing protein A (TIFA)	OTIRCVG7	TIFA_HUMAN	Increases Expression	[25]
DNA damage-inducible transcript 4-like protein (DDIT4L)	OT26Z2KN	DDT4L_HUMAN	Increases Expression	[25]
Endoplasmic reticulum resident protein 27 (ERP27)	OTVMGE2H	ERP27_HUMAN	Increases Expression	[25]
Dynein regulatory complex protein 10 (IQCD)	OT3TT4XO	DRC10_HUMAN	Increases Expression	[25]
E3 ubiquitin-protein ligase RNFT2 (RNFT2)	OTGIY43B	RNFT2_HUMAN	Decreases Expression	[25]
Cytoplasmic FMR1-interacting protein 2 (CYFIP2)	OTCAY35T	CYFP2_HUMAN	Decreases Expression	[25]
E3 ubiquitin-protein ligase pellino homolog 1 (PELI1)	OTMLBCLC	PELI1_HUMAN	Increases Expression	[25]
Multidrug and toxin extrusion protein 1 (SLC47A1)	OTZX0U5Q	S47A1_HUMAN	Decreases Expression	[25]
ERO1-like protein alpha (ERO1A)	OTVKOQWM	ERO1A_HUMAN	Increases Expression	[25]
PC-esterase domain-containing protein 1B (PCED1B)	OT19CDAB	PED1B_HUMAN	Increases Expression	[25]
Epithelial-stromal interaction protein 1 (EPSTI1)	OT75I1UH	ESIP1_HUMAN	Increases Expression	[25]
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)	OT9Z16M2	LMBL3_HUMAN	Decreases Expression	[25]
Solute carrier family 45 member 3 (SLC45A3)	OT08KS8J	S45A3_HUMAN	Decreases Expression	[25]
Lymphokine-activated killer T-cell-originated protein kinase (PBK)	OT5Z27TW	TOPK_HUMAN	Decreases Expression	[25]
Protein LRATD2 (LRATD2)	OTEZBUUL	LRAT2_HUMAN	Decreases Expression	[25]
TNFAIP3-interacting protein 3 (TNIP3)	OTSAE5UE	TNIP3_HUMAN	Increases Expression	[25]
Rho-related GTP-binding protein RhoV (RHOV)	OTW4N3QN	RHOV_HUMAN	Increases Expression	[25]
Fc receptor-like protein 2 (FCRL2)	OT0RLDOD	FCRL2_HUMAN	Increases Expression	[25]
Bcl-2-modifying factor (BMF)	OT90NSLI	BMF_HUMAN	Increases Expression	[25]
RIPOR family member 3 (RIPOR3)	OTHZ4RKK	RIPR3_HUMAN	Decreases Expression	[25]
Pseudokinase FAM20A (FAM20A)	OT5Z5IW8	FA20A_HUMAN	Increases Expression	[25]
Sterile alpha motif domain-containing protein 11 (SAMD11)	OT6WRQOX	SAM11_HUMAN	Decreases Expression	[25]
Fc receptor-like protein 3 (FCRL3)	OTIFXFWL	FCRL3_HUMAN	Increases Expression	[25]
Transcriptional-regulating factor 1 (TRERF1)	OTA7UQF1	TREF1_HUMAN	Increases Expression	[25]
Guanylate-binding protein 5 (GBP5)	OTS4AO4A	GBP5_HUMAN	Increases Expression	[25]
Guanylate-binding protein 4 (GBP4)	OTSPNGKX	GBP4_HUMAN	Increases Expression	[25]
Rho GTPase-activating protein 7 (DLC1)	OTP8LMCR	RHG07_HUMAN	Decreases Expression	[25]
Bile acid receptor (NR1H4)	OTWZLPTB	NR1H4_HUMAN	Decreases Expression	[25]
Small proline-rich protein 2F (SPRR2F)	OTJ4ZWF2	SPR2F_HUMAN	Increases Expression	[25]
L-amino-acid oxidase (IL4I1)	OTK54C63	OXLA_HUMAN	Increases Expression	[25]
Formin-binding protein 1 (FNBP1)	OTSJ5KKA	FNBP1_HUMAN	Increases Expression	[25]
Hemicentin-1 (HMCN1)	OTLZAS0P	HMCN1_HUMAN	Decreases Expression	[25]
Hyaluronan and proteoglycan link protein 3 (HAPLN3)	OTB853Z1	HPLN3_HUMAN	Increases Expression	[25]
Tetraspanin-18 (TSPAN18)	OTHSGPVB	TSN18_HUMAN	Increases Expression	[25]
Transcription factor ATOH8 (ATOH8)	OT7SY3BN	ATOH8_HUMAN	Increases Expression	[25]
Plakophilin-4 (PKP4)	OTQHOF8L	PKP4_HUMAN	Decreases Expression	[25]
P2X purinoceptor 4 (P2RX4)	OTEGBTE1	P2RX4_HUMAN	Increases Expression	[25]
Fasciculation and elongation protein zeta-1 (FEZ1)	OTWCXPRE	FEZ1_HUMAN	Increases Expression	[25]
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF)	OTT5JX1F	LITAF_HUMAN	Increases Expression	[25]
Paired mesoderm homeobox protein 2 (PRRX2)	OT8UR4AU	PRRX2_HUMAN	Increases Expression	[25]
Growth/differentiation factor 15 (GDF15)	OTWQN50N	GDF15_HUMAN	Decreases Expression	[25]
Ras-like protein family member 11B (RASL11B)	OTHEVZS6	RSLBB_HUMAN	Decreases Expression	[25]
Condensin complex subunit 3 (NCAPG)	OT1AI9EO	CND3_HUMAN	Decreases Expression	[25]
Potassium voltage-gated channel subfamily S member 3 (KCNS3)	OTHDD9F6	KCNS3_HUMAN	Increases Expression	[25]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (PLCD4)	OT14EZVB	PLCD4_HUMAN	Decreases Expression	[25]
Spexin (SPX)	OTY3G4AR	SPXN_HUMAN	Increases Expression	[25]
Proline-rich protein 15-like protein (PRR15L)	OT6J9UKK	PR15L_HUMAN	Decreases Expression	[25]
EF-hand domain-containing protein D1 (EFHD1)	OTL5INE4	EFHD1_HUMAN	Decreases Expression	[25]
Bublin coiled-coil protein (BBLN)	OTUMVEWE	BBLN_HUMAN	Increases Expression	[25]
Kinesin-like protein KIFC1 (KIFC1)	OTNQDS00	KIFC1_HUMAN	Decreases Expression	[25]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2)	OTZ092ZJ	THIC_HUMAN	Increases Expression	[25]
Cell division cycle-associated protein 7 (CDCA7)	OT12HDZY	CDCA7_HUMAN	Decreases Expression	[25]
Caspase recruitment domain-containing protein 10 (CARD10)	OT2RPM4I	CAR10_HUMAN	Decreases Expression	[25]
Succinate receptor 1 (SUCNR1)	OTFDSNET	SUCR1_HUMAN	Decreases Expression	[25]
Complement C1q tumor necrosis factor-related protein 6 (C1QTNF6)	OT57EPQC	C1QT6_HUMAN	Decreases Expression	[25]
Complement C1q tumor necrosis factor-related protein 1 (C1QTNF1)	OT7I7KHC	C1QT1_HUMAN	Increases Expression	[25]
FSD1-like protein (FSD1L)	OTBQ48RF	FSD1L_HUMAN	Increases Expression	[25]
Pappalysin-2 (PAPPA2)	OTXYGTUZ	PAPP2_HUMAN	Decreases Expression	[25]
Alpha-(1,6)-fucosyltransferase (FUT8)	OTJJCVG1	FUT8_HUMAN	Increases Expression	[25]
NF-kappa-B inhibitor zeta (NFKBIZ)	OTU728KS	IKBZ_HUMAN	Increases Expression	[25]
Tripartite motif-containing protein 55 (TRIM55)	OTY5YQFX	TRI55_HUMAN	Increases Expression	[25]
Protein Niban 1 (NIBAN1)	OTYOLI12	NIBA1_HUMAN	Increases Expression	[25]
Normal mucosa of esophagus-specific gene 1 protein (C15ORF48)	OT85J32K	NMES1_HUMAN	Increases Expression	[25]
cAMP-dependent protein kinase inhibitor beta (PKIB)	OT7C8GFN	IPKB_HUMAN	Decreases Expression	[25]
182 kDa tankyrase-1-binding protein (TNKS1BP1)	OTBIZECQ	TB182_HUMAN	Increases Expression	[25]
Phosphatase and actin regulator 1 (PHACTR1)	OTAMPX9V	PHAR1_HUMAN	Increases Expression	[25]
Glutamate receptor-interacting protein 2 (GRIP2)	OT8DGYZ5	GRIP2_HUMAN	Increases Expression	[25]
Metal cation symporter ZIP8 (SLC39A8)	OT6C6MNV	S39A8_HUMAN	Increases Expression	[25]
Olfactory receptor 2H1 (OR2H1)	OT69YZTJ	OR2H1_HUMAN	Increases Expression	[25]
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19)	OTH88TXU	ADA19_HUMAN	Decreases Expression	[25]
Solute carrier family 22 member 4 (SLC22A4)	OT4LOVI9	S22A4_HUMAN	Increases Expression	[25]
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1)	OT4U7SBG	GBRL1_HUMAN	Decreases Expression	[25]
Syntenin-2 (SDCBP2)	OT1AT2OL	SDCB2_HUMAN	Increases Expression	[25]
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL)	OTV8MNT1	I2BPL_HUMAN	Decreases Expression	[25]
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (SLC35B3)	OTBDPI8I	S35B3_HUMAN	Increases Expression	[25]
DNA replication factor Cdt1 (CDT1)	OTVY53VG	CDT1_HUMAN	Decreases Expression	[25]
2-aminomuconic semialdehyde dehydrogenase (ALDH8A1)	OTINY3MW	AL8A1_HUMAN	Increases Expression	[25]
C-X-C motif chemokine 16 (CXCL16)	OTD49T9R	CXL16_HUMAN	Increases Expression	[25]
Probable serine carboxypeptidase CPVL (CPVL)	OTOJL31C	CPVL_HUMAN	Decreases Expression	[25]
BolA-like protein 2 (BOLA2)	OTVZP6YB	BOLA2_HUMAN	Increases Expression	[25]
SPARC-related modular calcium-binding protein 2 (SMOC2)	OTK1EQ49	SMOC2_HUMAN	Increases Expression	[25]
Protein salvador homolog 1 (SAV1)	OTSAEV92	SAV1_HUMAN	Increases Expression	[25]
Very long chain fatty acid elongase 6 (ELOVL6)	OTB26UJJ	ELOV6_HUMAN	Increases Expression	[25]
DENN domain-containing protein 2D (DENND2D)	OTXEFJWM	DEN2D_HUMAN	Increases Expression	[25]
Transcription factor SOX-17 (SOX17)	OT9H4WWE	SOX17_HUMAN	Increases Expression	[25]
Reticulophagy regulator 1 (RETREG1)	OTYOSLZX	RETR1_HUMAN	Increases Expression	[25]
Leucine-rich repeat-containing protein 19 (LRRC19)	OTQDUW2A	LRC19_HUMAN	Decreases Expression	[25]
SH2 domain-containing protein 4A (SH2D4A)	OTH562MY	SH24A_HUMAN	Increases Expression	[25]
Protein eva-1 homolog A (EVA1A)	OTCY3Q2M	EVA1A_HUMAN	Decreases Expression	[25]
Succinate--hydroxymethylglutarate CoA-transferase (SUGCT)	OTA8L0TN	SUCHY_HUMAN	Increases Expression	[25]
Solute carrier family 28 member 3 (SLC28A3)	OT5TLTYU	S28A3_HUMAN	Increases Expression	[25]
V-type proton ATPase 116 kDa subunit a 4 (ATP6V0A4)	OT149Z7Q	VPP4_HUMAN	Decreases Expression	[25]
Relaxin receptor 1 (RXFP1)	OTW4O1OO	RXFP1_HUMAN	Increases Expression	[25]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2)	OTAQD3YV	ARNT2_HUMAN	Decreases Expression	[25]
Transcription factor HES-4 (HES4)	OTCGMQDT	HES4_HUMAN	Decreases Expression	[25]
Synaptotagmin-like protein 2 (SYTL2)	OTUIOWKL	SYTL2_HUMAN	Decreases Expression	[25]
Protein S100-A14 (S100A14)	OTVFJJ91	S10AE_HUMAN	Decreases Expression	[25]
3',5'-cyclic-AMP phosphodiesterase 7B (PDE7B)	OTK3SHT2	PDE7B_HUMAN	Decreases Expression	[25]
ATP-binding cassette sub-family B member 6 (ABCB6)	OTPGZFES	ABCB6_HUMAN	Decreases Expression	[25]
Solute carrier family 40 member 1 (SLC40A1)	OT8RV2VY	S40A1_HUMAN	Increases Expression	[25]
Sodium- and chloride-dependent transporter XTRP3 (SLC6A20)	OTHRD4XO	S6A20_HUMAN	Increases Expression	[25]
Partitioning defective 6 homolog alpha (PARD6A)	OTWLV3X1	PAR6A_HUMAN	Decreases Expression	[25]
Lactosylceramide 4-alpha-galactosyltransferase (A4GALT)	OTPX3UGY	A4GAT_HUMAN	Increases Expression	[25]
Uncharacterized protein C14orf132 (C14ORF132)	OTBVC3AO	CN132_HUMAN	Decreases Expression	[25]
A-kinase-interacting protein 1 (AKIP1)	OT7XPG27	AKIP1_HUMAN	Increases Expression	[25]
Nuclear receptor-interacting protein 3 (NRIP3)	OTU15GMK	NRIP3_HUMAN	Increases Expression	[25]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1)	OT9HYT7A	PLCB1_HUMAN	Decreases Expression	[25]
Anillin (ANLN)	OTXJY54C	ANLN_HUMAN	Decreases Expression	[25]
Transcriptional and immune response regulator (TCIM)	OTARUXQF	TCIM_HUMAN	Increases Expression	[25]
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2)	OTB1FZJU	ACSA_HUMAN	Increases Expression	[25]
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (MAN1C1)	OT44TM7D	MA1C1_HUMAN	Decreases Expression	[25]
Rho guanine nucleotide exchange factor 4 (ARHGEF4)	OTR2VG0W	ARHG4_HUMAN	Decreases Expression	[25]
Platelet-derived growth factor C (PDGFC)	OT3ZJ0XU	PDGFC_HUMAN	Decreases Expression	[25]
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1)	OTKJ44KY	PRDC1_HUMAN	Decreases Expression	[25]
C-C motif chemokine 28 (CCL28)	OTY6XNQ7	CCL28_HUMAN	Increases Expression	[25]
Interleukin-17 receptor B (IL17RB)	OT0KDNSF	I17RB_HUMAN	Decreases Expression	[25]
Single-pass membrane and coiled-coil domain-containing protein 4 (SMCO4)	OTDLEXH4	SMCO4_HUMAN	Decreases Expression	[25]
MAP3K12-binding inhibitory protein 1 (MBIP)	OTORHZ9Y	MBIP1_HUMAN	Increases Expression	[25]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1)	OT3JQD99	SIA7A_HUMAN	Increases Expression	[25]
Centromere protein M (CENPM)	OTYK9KOX	CENPM_HUMAN	Decreases Expression	[25]
Protein diaphanous homolog 3 (DIAPH3)	OTPOT23F	DIAP3_HUMAN	Decreases Expression	[25]
Protein DEPP1 (DEPP1)	OTB36PHJ	DEPP1_HUMAN	Increases Expression	[25]
SERTA domain-containing protein 4 (SERTAD4)	OTZ1GUD9	SRTD4_HUMAN	Decreases Expression	[25]
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5)	OTNY3VMD	PLCE_HUMAN	Increases Expression	[25]
Transmembrane protein 74B (TMEM74B)	OTM7QFEC	TM74B_HUMAN	Increases Expression	[25]
Serine palmitoyltransferase 3 (SPTLC3)	OTZDX6PT	SPTC3_HUMAN	Decreases Expression	[25]
Spermine oxidase (SMOX)	OT11E62Y	SMOX_HUMAN	Decreases Expression	[25]
Syntabulin (SYBU)	OT3FQV7N	SYBU_HUMAN	Decreases Expression	[25]
Membrane progestin receptor gamma (PAQR5)	OTGGWXQE	PAQR5_HUMAN	Decreases Expression	[25]
CDKN2A-interacting protein (CDKN2AIP)	OT80RRQJ	CARF_HUMAN	Decreases Expression	[25]
Serine/threonine-protein kinase 32B (STK32B)	OTIRBJ96	ST32B_HUMAN	Decreases Expression	[25]
Molybdenum cofactor biosynthesis protein 1 (MOCS1)	OTDCTCRU	MOCS1_HUMAN	Increases Expression	[25]
Ninjurin-2 (NINJ2)	OTUG1AOV	NINJ2_HUMAN	Decreases Expression	[25]
Interleukin-36 gamma (IL36G)	OT19IAAS	IL36G_HUMAN	Increases Expression	[25]
Transcription factor CP2-like protein 1 (TFCP2L1)	OT7QIJ0X	TF2L1_HUMAN	Decreases Expression	[25]
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (COQ3)	OTSGT89T	COQ3_HUMAN	Decreases Expression	[25]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Increases Expression	[25]
Ankycorbin (RAI14)	OT6USGBK	RAI14_HUMAN	Decreases Expression	[25]
Serine/threonine-protein kinase pim-2 (PIM2)	OTHQGU3I	PIM2_HUMAN	Increases Expression	[25]
Semaphorin-5B (SEMA5B)	OTUVSKK0	SEM5B_HUMAN	Decreases Expression	[25]
Coiled-coil and C2 domain-containing protein 2A (CC2D2A)	OTFGRGFR	C2D2A_HUMAN	Decreases Expression	[25]
Cingulin (CGN)	OTBCQ8AQ	CING_HUMAN	Decreases Expression	[25]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9)	OTV3Q0DS	ATS9_HUMAN	Increases Expression	[25]
Kelch-like protein 13 (KLHL13)	OTUNG578	KLH13_HUMAN	Decreases Expression	[25]
Stomatin-like protein 1 (STOML1)	OTSIO2QA	STML1_HUMAN	Increases Expression	[25]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)	OTHCDQ22	PRGC1_HUMAN	Decreases Expression	[25]
7-dehydrocholesterol reductase (DHCR7)	OTLILBUI	DHCR7_HUMAN	Increases Expression	[25]
Fibulin-5 (FBLN5)	OTLVNZ8U	FBLN5_HUMAN	Increases Expression	[25]
Protein phosphatase 1 regulatory subunit 1B (PPP1R1B)	OTSIJMQ9	PPR1B_HUMAN	Decreases Expression	[25]
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1)	OTM3H5OA	MALT1_HUMAN	Increases Expression	[25]
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD)	OTP9COQT	PISD_HUMAN	Increases Expression	[25]
NPC1-like intracellular cholesterol transporter 1 (NPC1L1)	OT6GWW1P	NPCL1_HUMAN	Increases Expression	[25]
Interleukin-19 (IL19)	OT9VGDIP	IL19_HUMAN	Increases Expression	[25]
N-acetyltransferase 8 (NAT8)	OTU9OWOW	NAT8_HUMAN	Decreases Expression	[25]
STEAP1 protein (STEAP1)	OTJMW5R9	STEA1_HUMAN	Increases Expression	[25]
Doublecortin domain-containing protein 2 (DCDC2)	OTSUFH1H	DCDC2_HUMAN	Decreases Expression	[25]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)	OTTLJH8W	ATS1_HUMAN	Increases Expression	[25]
General transcription factor II-I repeat domain-containing protein 1 (GTF2IRD1)	OTEG9KU1	GT2D1_HUMAN	Decreases Expression	[25]
Carboxypeptidase A4 (CPA4)	OT66MP0F	CBPA4_HUMAN	Decreases Expression	[25]
Regulating synaptic membrane exocytosis protein 3 (RIMS3)	OTHN3H0A	RIMS3_HUMAN	Decreases Expression	[25]
Tubulointerstitial nephritis antigen (TINAG)	OTY7BSD7	TINAG_HUMAN	Decreases Expression	[25]
Heat shock protein beta-8 (HSPB8)	OT0I83YS	HSPB8_HUMAN	Increases Expression	[25]
Paired immunoglobulin-like type 2 receptor alpha (PILRA)	OTBE0PLF	PILRA_HUMAN	Increases Expression	[25]
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM28)	OT3GBVHL	ADA28_HUMAN	Increases Expression	[25]
Histone deacetylase 9 (HDAC9)	OTO8O0LF	HDAC9_HUMAN	Increases Expression	[25]
Procollagen C-endopeptidase enhancer 2 (PCOLCE2)	OTSUEQZ1	PCOC2_HUMAN	Decreases Expression	[25]
Dermatan-sulfate epimerase (DSE)	OTQ108VJ	DSE_HUMAN	Increases Expression	[25]
Long-chain-fatty-acid--CoA ligase 5 (ACSL5)	OT3L9XO3	ACSL5_HUMAN	Increases Expression	[25]
2-oxoglutarate dehydrogenase-like, mitochondrial (OGDHL)	OT1AZK6R	OGDHL_HUMAN	Decreases Expression	[25]
Potassium voltage-gated channel subfamily H member 3 (KCNH3)	OT3A9XB0	KCNH3_HUMAN	Decreases Expression	[25]
DENN domain-containing protein 2A (DENND2A)	OT01E1PL	DEN2A_HUMAN	Decreases Expression	[25]
Zinc transporter ZIP10 (SLC39A10)	OT04411Q	S39AA_HUMAN	Decreases Expression	[25]
Protein HEG homolog 1 (HEG1)	OT3CUXA7	HEG1_HUMAN	Increases Expression	[25]
Protein NDRG4 (NDRG4)	OTJBOTD8	NDRG4_HUMAN	Increases Expression	[25]
Protein phosphatase 1H (PPM1H)	OTKSVU7S	PPM1H_HUMAN	Increases Expression	[25]
Targeting protein for Xklp2 (TPX2)	OTWLJYH0	TPX2_HUMAN	Decreases Expression	[25]
Transcription factor MafF (MAFF)	OT9B7MX0	MAFF_HUMAN	Increases Expression	[25]
C-type lectin domain family 4 member E (CLEC4E)	OT7P8ICY	CLC4E_HUMAN	Increases Expression	[25]
Hippocalcin-like protein 4 (HPCAL4)	OT793RNP	HPCL4_HUMAN	Decreases Expression	[25]
HERV-H LTR-associating protein 2 (HHLA2)	OTYBTVQS	HHLA2_HUMAN	Increases Expression	[25]
Neurogenic locus notch homolog protein 3 (NOTCH3)	OTMVVA7F	NOTC3_HUMAN	Decreases Expression	[25]
Rho GTPase-activating protein 26 (ARHGAP26)	OTNGQU7A	RHG26_HUMAN	Increases Expression	[25]
Dual specificity protein phosphatase CDC14A (CDC14A)	OTL10OY6	CC14A_HUMAN	Increases Expression	[25]
Cytosolic phospholipase A2 gamma (PLA2G4C)	OTIK5GT5	PA24C_HUMAN	Increases Expression	[25]
LIM and calponin homology domains-containing protein 1 (LIMCH1)	OTYPC4XA	LIMC1_HUMAN	Increases Expression	[25]
Inactive phospholipase C-like protein 2 (PLCL2)	OTK5FDF6	PLCL2_HUMAN	Increases Expression	[25]
VPS10 domain-containing receptor SorCS3 (SORCS3)	OT4VOMBC	SORC3_HUMAN	Decreases Expression	[25]
TBC1 domain family member 2B (TBC1D2B)	OT1GVN5H	TBD2B_HUMAN	Increases Expression	[25]
DNA replication complex GINS protein PSF2 (GINS2)	OT974IYI	PSF2_HUMAN	Decreases Expression	[25]
Leucine zipper putative tumor suppressor 1 (LZTS1)	OTXXL864	LZTS1_HUMAN	Decreases Expression	[25]
Beta-1,3-galactosyltransferase 5 (B3GALT5)	OTWXPEMU	B3GT5_HUMAN	Decreases Expression	[25]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5)	OT03QCLM	ATF5_HUMAN	Increases Expression	[25]
Netrin-G1 (NTNG1)	OTF48IID	NTNG1_HUMAN	Decreases Expression	[25]
Calsenilin (KCNIP3)	OTCQPEM4	CSEN_HUMAN	Increases Expression	[25]
StAR-related lipid transfer protein 13 (STARD13)	OTB4U1HY	STA13_HUMAN	Decreases Expression	[25]
Sal-like protein 2 (SALL2)	OTQWI68Q	SALL2_HUMAN	Decreases Expression	[25]
Transcription factor HES-2 (HES2)	OTMWY2KV	HES2_HUMAN	Decreases Expression	[25]
Claudin-16 (CLDN16)	OTTHAIKR	CLD16_HUMAN	Decreases Expression	[25]
Retinoic acid-induced protein 2 (RAI2)	OTR8LX4J	RAI2_HUMAN	Increases Expression	[25]
Transcription factor MafB (MAFB)	OTH2N3T8	MAFB_HUMAN	Increases Expression	[25]
Transient receptor potential cation channel subfamily V member 2 (TRPV2)	OT0A9AVD	TRPV2_HUMAN	Decreases Expression	[25]
Neuropeptide FF receptor 2 (NPFFR2)	OTVI4Q85	NPFF2_HUMAN	Increases Expression	[25]
Endothelial lipase (LIPG)	OTHEE942	LIPG_HUMAN	Increases Expression	[25]
Phosphoserine aminotransferase (PSAT1)	OTVV1YV9	SERC_HUMAN	Decreases Expression	[25]
Adhesion G-protein coupled receptor G1 (ADGRG1)	OTQBB8NT	AGRG1_HUMAN	Decreases Expression	[25]
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (HS3ST3A1)	OTUOM1GV	HS3SA_HUMAN	Increases Expression	[25]
LHFPL tetraspan subfamily member 6 protein (LHFPL6)	OTY6LHJY	LHPL6_HUMAN	Increases Expression	[25]
Transforming acidic coiled-coil-containing protein 3 (TACC3)	OTRNEZTA	TACC3_HUMAN	Decreases Expression	[25]
AP-4 complex subunit beta-1 (AP4B1)	OTGJUIRA	AP4B1_HUMAN	Increases Expression	[25]
Choline/ethanolaminephosphotransferase 1 (CEPT1)	OT8K1UV2	CEPT1_HUMAN	Increases Expression	[25]
Adenylate kinase isoenzyme 5 (AK5)	OTTGXLOT	KAD5_HUMAN	Decreases Expression	[25]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR)	OTTLD0KB	SQOR_HUMAN	Increases Expression	[25]
Calpain-6 (CAPN6)	OT8K5PR5	CAN6_HUMAN	Decreases Expression	[25]
Electrogenic sodium bicarbonate cotransporter 1 (SLC4A4)	OT727K92	S4A4_HUMAN	Decreases Expression	[25]
IgGFc-binding protein (FCGBP)	OT63T6XQ	FCGBP_HUMAN	Increases Expression	[25]
SET-binding protein (SETBP1)	OTKGCOSR	SETBP_HUMAN	Decreases Expression	[25]
Influenza virus NS1A-binding protein (IVNS1ABP)	OTYHL4I7	NS1BP_HUMAN	Decreases Expression	[25]
Pirin (PIR)	OT8ALXHU	PIR_HUMAN	Increases Expression	[26]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)	OTLVN68B	AAKB2_HUMAN	Decreases Expression	[26]
Asparagine--tRNA ligase, cytoplasmic (NARS1)	OTFS4J1W	SYNC_HUMAN	Decreases Expression	[26]
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A)	OT4RF9Z4	PDE8A_HUMAN	Increases Expression	[26]
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21)	OT3EDGXO	TNR21_HUMAN	Decreases Expression	[26]
Breast cancer anti-estrogen resistance protein 3 (BCAR3)	OTPJ17M8	BCAR3_HUMAN	Decreases Expression	[26]
G1/S-specific cyclin-E2 (CCNE2)	OTBBUKQQ	CCNE2_HUMAN	Decreases Expression	[26]
Ferritin heavy chain (FTH1)	OT6IFS0O	FRIH_HUMAN	Increases Expression	[26]
Glycogen phosphorylase, liver form (PYGL)	OTS1YFGR	PYGL_HUMAN	Decreases Expression	[26]
Bifunctional glutamate/proline--tRNA ligase (EPRS1)	OTXK0FLB	SYEP_HUMAN	Decreases Expression	[26]
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1)	OTV04QE5	P4HA1_HUMAN	Increases Expression	[26]
Aspartate aminotransferase, cytoplasmic (GOT1)	OTZLM5UB	AATC_HUMAN	Increases Expression	[26]
Keratin, type I cytoskeletal 15 (KRT15)	OTS6WLF7	K1C15_HUMAN	Increases Expression	[26]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)	OTB06ESI	ACSL1_HUMAN	Decreases Expression	[26]
Aryl hydrocarbon receptor (AHR)	OTFE4EYE	AHR_HUMAN	Affects Activity	[26]
Peroxisome proliferator-activated receptor gamma (PPARG)	OTHMARHO	PPARG_HUMAN	Affects Activity	[26]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9)	OTV9L89D	TNFL9_HUMAN	Increases Expression	[26]
Alanine--tRNA ligase, cytoplasmic (AARS1)	OTW8D813	SYAC_HUMAN	Decreases Expression	[26]
Aldo-keto reductase family 1 member C2 (AKR1C2)	OTQ2XMO3	AK1C2_HUMAN	Decreases Expression	[26]
Dipeptidyl peptidase 1 (CTSC)	OT79WJZZ	CATC_HUMAN	Increases Expression	[26]
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)	OT6W40XU	P5CS_HUMAN	Decreases Expression	[26]
Homeobox protein DLX-1 (DLX1)	OT7BH057	DLX1_HUMAN	Decreases Expression	[26]
Protein BTG2 (BTG2)	OTZF6K1H	BTG2_HUMAN	Decreases Expression	[26]
Runt-related transcription factor 2 (RUNX2)	OT97RQQM	RUNX2_HUMAN	Increases Expression	[26]
Src substrate cortactin (CTTN)	OTJRG4ES	SRC8_HUMAN	Decreases Expression	[26]
Plectin (PLEC)	OTU4XDEG	PLEC_HUMAN	Decreases Expression	[26]
Neutral amino acid transporter B(0) (SLC1A5)	OTE2H26Q	AAAT_HUMAN	Decreases Expression	[26]
Atos homolog protein A (ATOSA)	OTWFM5G0	ATOSA_HUMAN	Increases Expression	[26]
FRAS1-related extracellular matrix protein 2 (FREM2)	OTEK6BZR	FREM2_HUMAN	Decreases Expression	[26]
Extracellular sulfatase Sulf-2 (SULF2)	OTIXMUVL	SULF2_HUMAN	Increases Expression	[26]
Ninjurin-1 (NINJ1)	OTLRZ1EU	NINJ1_HUMAN	Decreases Expression	[26]
KICSTOR complex protein ITFG2 (ITFG2)	OT0NLZ8I	ITFG2_HUMAN	Decreases Expression	[26]
Aurora kinase B (AURKB)	OTIY4VHU	AURKB_HUMAN	Decreases Expression	[26]
Protein FAM167A (FAM167A)	OT9JF3JQ	F167A_HUMAN	Decreases Expression	[26]
E1A-binding protein p400 (EP400)	OTVQ75NX	EP400_HUMAN	Decreases Expression	[26]
Cancer-related nucleoside-triphosphatase (NTPCR)	OTTRT6Z9	NTPCR_HUMAN	Increases Expression	[26]
Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11)	OTNC55HX	GTR11_HUMAN	Decreases Expression	[26]
Polyprenol reductase (SRD5A3)	OT9IJLX7	PORED_HUMAN	Increases Expression	[26]
Ankyrin repeat family A protein 2 (ANKRA2)	OTLSLV5A	ANRA2_HUMAN	Increases Expression	[26]
Fructose-2,6-bisphosphatase TIGAR (TIGAR)	OTR7NMRJ	TIGAR_HUMAN	Decreases Expression	[26]
DNA damage-inducible transcript 4 protein (DDIT4)	OTHY8SY4	DDIT4_HUMAN	Decreases Expression	[26]
SERTA domain-containing protein 1 (SERTAD1)	OTBHKZQP	SRTD1_HUMAN	Decreases Expression	[26]
GTP:AMP phosphotransferase AK3, mitochondrial (AK3)	OTM59ZGG	KAD3_HUMAN	Decreases Expression	[26]
Oxidative stress-induced growth inhibitor 1 (OSGIN1)	OT9KIVZW	OSGI1_HUMAN	Decreases Expression	[26]
Two pore channel protein 1 (TPCN1)	OTT4C4DI	TPC1_HUMAN	Increases Expression	[26]
Ras-related protein Rab-26 (RAB26)	OTHMPRJK	RAB26_HUMAN	Increases Expression	[26]
Lysine-specific demethylase 3A (KDM3A)	OTZYJ8VN	KDM3A_HUMAN	Increases Expression	[26]
Pleckstrin homology-like domain family A member 3 (PHLDA3)	OTXFUDO2	PHLA3_HUMAN	Decreases Expression	[26]
Sestrin-1 (SESN1)	OTSFDZWL	SESN1_HUMAN	Decreases Expression	[26]
Rho guanine nucleotide exchange factor 35 (ARHGEF35)	OTLX3XDA	ARG35_HUMAN	Decreases Expression	[27]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L)	OT7QO47I	RBG10_HUMAN	Decreases Expression	[27]
Agrin (AGRN)	OTWJENAZ	AGRIN_HUMAN	Increases Expression	[27]
Apoptotic protease-activating factor 1 (APAF1)	OTJWIVY0	APAF_HUMAN	Increases Expression	[27]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1)	OTIK337D	TGFI1_HUMAN	Increases Expression	[27]
Alpha-actinin-4 (ACTN4)	OTCNZAJ5	ACTN4_HUMAN	Decreases Expression	[27]
Fatty acid CoA ligase Acsl3 (ACSL3)	OT3MWER1	ACSL3_HUMAN	Decreases Expression	[27]
Metalloproteinase inhibitor 1 (TIMP1)	OTOXC51H	TIMP1_HUMAN	Increases Expression	[27]
Cystatin-C (CST3)	OTNZ6AO4	CYTC_HUMAN	Increases Expression	[27]
GTPase KRas (KRAS)	OT78QCN8	RASK_HUMAN	Increases Expression	[27]
Transforming growth factor beta-1 proprotein (TGFB1)	OTV5XHVH	TGFB1_HUMAN	Increases Expression	[27]
Fibronectin (FN1)	OTB5ZN4Q	FINC_HUMAN	Increases Expression	[27]
Alpha-2-HS-glycoprotein (AHSG)	OTUG0LEA	FETUA_HUMAN	Increases Expression	[27]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Increases Expression	[27]
Alpha-fetoprotein (AFP)	OT9GG3ZI	FETA_HUMAN	Increases Expression	[27]
Vitamin D-binding protein (GC)	OTWS63BY	VTDB_HUMAN	Increases Expression	[27]
Lactotransferrin (LTF)	OT8JWCZ0	TRFL_HUMAN	Increases Expression	[27]
Metallothionein-1A (MT1A)	OTKBH52X	MT1A_HUMAN	Increases Expression	[27]
Alpha-galactosidase A (GLA)	OTBSR6DT	AGAL_HUMAN	Decreases Expression	[27]
Protein S100-A6 (S100A6)	OTHHPZQ8	S10A6_HUMAN	Decreases Expression	[27]
Annexin A2 (ANXA2)	OTFNS0CC	ANXA2_HUMAN	Decreases Expression	[27]
Tropomyosin beta chain (TPM2)	OTA1L0P8	TPM2_HUMAN	Decreases Expression	[27]
Rho-related GTP-binding protein RhoC (RHOC)	OTOLE1FT	RHOC_HUMAN	Affects Localization	[27]
Calmodulin-1 (CALM2)	OTNYA92F	CALM1_HUMAN	Decreases Expression	[27]
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB)	OT2NHE5E	ODPB_HUMAN	Increases Expression	[27]
Ras-related protein Ral-A (RALA)	OT734R7X	RALA_HUMAN	Increases Expression	[27]
Lysosome-associated membrane glycoprotein 1 (LAMP1)	OTYE92QY	LAMP1_HUMAN	Decreases Expression	[27]
Alpha-actinin-1 (ACTN1)	OTUCLNXH	ACTN1_HUMAN	Decreases Expression	[27]
Translationally-controlled tumor protein (TPT1)	OTHMTRJU	TCTP_HUMAN	Decreases Expression	[27]
Metalloproteinase inhibitor 2 (TIMP2)	OT8S1RRP	TIMP2_HUMAN	Increases Expression	[27]
Heat shock 70 kDa protein 6 (HSPA6)	OTH4S7WB	HSP76_HUMAN	Increases Expression	[27]
Cation-dependent mannose-6-phosphate receptor (M6PR)	OTFEWOSB	MPRD_HUMAN	Decreases Expression	[27]
Collagen alpha-1(V) chain (COL5A1)	OT24078H	CO5A1_HUMAN	Increases Expression	[27]
Cofilin-1 (CFL1)	OTT6D5MH	COF1_HUMAN	Increases Expression	[27]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Decreases Expression	[27]
Cartilage oligomeric matrix protein (COMP)	OTS2FPMI	COMP_HUMAN	Increases Expression	[27]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 (GNG10)	OTLMZGBE	GBG10_HUMAN	Increases Expression	[27]
Rab GDP dissociation inhibitor beta (GDI2)	OTGLY3I7	GDIB_HUMAN	Increases Expression	[27]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)	OTI862QH	CPT1A_HUMAN	Decreases Expression	[27]
Ras-related protein Rab-7a (RAB7A)	OTBSPWMQ	RAB7A_HUMAN	Increases Expression	[27]
Ras-related protein Rab-9A (RAB9A)	OTO9VJS9	RAB9A_HUMAN	Increases Expression	[27]
Rho GDP-dissociation inhibitor 1 (ARHGDIA)	OTEXWJDO	GDIR1_HUMAN	Decreases Expression	[27]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Increases Expression	[27]
Heat shock-related 70 kDa protein 2 (HSPA2)	OTSDET7B	HSP72_HUMAN	Increases Expression	[27]
Ras-related protein Rab-10 (RAB10)	OT8ZN26V	RAB10_HUMAN	Increases Expression	[27]
Ras-related protein R-Ras2 (RRAS2)	OT83NCEB	RRAS2_HUMAN	Increases Expression	[27]
Thymosin beta-4 (TMSB4X)	OT9HPLP3	TYB4_HUMAN	Decreases Expression	[27]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Increases Expression	[27]
E3 ubiquitin-protein ligase RBX1 (RBX1)	OTYA1UIO	RBX1_HUMAN	Decreases Expression	[27]
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2)	OT3JPRCQ	GBB2_HUMAN	Increases Expression	[27]
Ras-related C3 botulinum toxin substrate 1 (RAC1)	OTKRO61U	RAC1_HUMAN	Increases Expression	[27]
S-phase kinase-associated protein 1 (SKP1)	OT5BPAZ4	SKP1_HUMAN	Decreases Expression	[27]
Small ribosomal subunit protein RACK1 (RACK1)	OTZBCQ1U	RACK1_HUMAN	Increases Expression	[27]
Thymosin beta-10 (TMSB10)	OTLVZ13T	TYB10_HUMAN	Decreases Expression	[27]
Oxidized low-density lipoprotein receptor 1 (OLR1)	OTS44RIC	OLR1_HUMAN	Increases Expression	[27]
Rho-related GTP-binding protein RhoG (RHOG)	OTJ7J1WA	RHOG_HUMAN	Increases Expression	[27]
Ras association domain-containing protein 7 (RASSF7)	OT0V4EIZ	RASF7_HUMAN	Decreases Expression	[27]
Inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3)	OT4SLMLY	ITIH3_HUMAN	Increases Expression	[27]
Peroxisome proliferator-activated receptor alpha (PPARA)	OTK095PP	PPARA_HUMAN	Decreases Expression	[27]
Metastasis-associated protein MTA1 (MTA1)	OTBHW3S9	MTA1_HUMAN	Decreases Expression	[27]
Origin recognition complex subunit 2 (ORC2)	OTLIYP8M	ORC2_HUMAN	Decreases Expression	[27]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1)	OT6VY3A3	SPTN1_HUMAN	Decreases Expression	[27]
Lysosome membrane protein 2 (SCARB2)	OTN929M8	SCRB2_HUMAN	Decreases Expression	[27]
Reticulocalbin-2 (RCN2)	OTIU8JWD	RCN2_HUMAN	Decreases Expression	[27]
Beclin-1 (BECN1)	OT4X293M	BECN1_HUMAN	Decreases Expression	[27]
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1)	OTM0A0DY	ACOX1_HUMAN	Decreases Expression	[27]
Ras-related protein Rab-35 (RAB35)	OTRH1E2T	RAB35_HUMAN	Increases Expression	[27]
Reticulocalbin-1 (RCN1)	OT3JBGAG	RCN1_HUMAN	Decreases Expression	[27]
Calcium/calmodulin-dependent protein kinase type IV (CAMK4)	OT47RDGV	KCC4_HUMAN	Decreases Expression	[27]
Autophagy-related protein 2 homolog A (ATG2A)	OTGYDDSV	ATG2A_HUMAN	Increases Expression	[27]
Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1)	OT1N2182	CAMP1_HUMAN	Decreases Expression	[27]
Protein MON2 homolog (MON2)	OTCSVMAR	MON2_HUMAN	Increases Expression	[27]
Spartin (SPART)	OTIVOS2I	SPART_HUMAN	Decreases Expression	[27]
Cohesin subunit SA-2 (STAG2)	OTR6X1Q7	STAG2_HUMAN	Decreases Expression	[27]
Anaphase-promoting complex subunit CDC26 (CDC26)	OTHYYBGH	CDC26_HUMAN	Decreases Expression	[27]
Ras-related protein Rab-2B (RAB2B)	OTEIYK4O	RAB2B_HUMAN	Increases Expression	[27]
Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1)	OT80QNR5	TGFA1_HUMAN	Increases Expression	[27]
Filamin-binding LIM protein 1 (FBLIM1)	OTFHXMON	FBLI1_HUMAN	Decreases Expression	[27]
Splicing factor Cactin (CACTIN)	OTO7UVK7	CATIN_HUMAN	Decreases Expression	[27]
Hepatitis A virus cellular receptor 1 (HAVCR1)	OT184CRZ	HAVR1_HUMAN	Increases Expression	[27]
Sororin (CDCA5)	OTZLCQ5U	CDCA5_HUMAN	Increases Expression	[27]
Charged multivesicular body protein 6 (CHMP6)	OT94GFIF	CHMP6_HUMAN	Increases Expression	[27]
Adenosine 5'-monophosphoramidase HINT2 (HINT2)	OTW9GS0U	HINT2_HUMAN	Increases Expression	[27]
Rab11 family-interacting protein 5 (RAB11FIP5)	OTNA33DE	RFIP5_HUMAN	Increases Expression	[27]
Kinesin-like protein KIF13A (KIF13A)	OTSSZGBQ	KI13A_HUMAN	Decreases Expression	[27]
Rab GTPase-binding effector protein 2 (RABEP2)	OTO61X27	RABE2_HUMAN	Decreases Expression	[27]
NADPH oxidase 4 (NOX4)	OTTYQ097	NOX4_HUMAN	Increases Expression	[27]
Rab-like protein 2B (RABL2B)	OTB7O3UJ	RBL2B_HUMAN	Increases Expression	[27]
Protein strawberry notch homolog 2 (SBNO2)	OT1C6J3K	SBNO2_HUMAN	Increases Expression	[27]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)	OTBPCU2O	TR10A_HUMAN	Increases Expression	[29]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Expression	[32]
CCN family member 1 (CCN1)	OTKJBEMD	CCN1_HUMAN	Decreases Expression	[33]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11)	OTJEPKEQ	TNF11_HUMAN	Decreases Expression	[34]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)	OTY9R6FZ	ERN1_HUMAN	Increases Expression	[35]
Geranylgeranyl pyrophosphate synthase (GGPS1)	OTVEHG28	GGPPS_HUMAN	Decreases Activity	[36]
BAG family molecular chaperone regulator 3 (BAG3)	OTVXYUDQ	BAG3_HUMAN	Increases Expression	[29]
GTPase HRas (HRAS)	OTWQN0DP	RASH_HUMAN	Decreases Localization	[37]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Increases Expression	[29]
Collagen alpha-1(I) chain (COL1A1)	OTI31178	CO1A1_HUMAN	Decreases Expression	[38]
Osteocalcin (BGLAP)	OTK1YLWQ	OSTCN_HUMAN	Increases Expression	[39]
RAF proto-oncogene serine/threonine-protein kinase (RAF1)	OT51LSFO	RAF1_HUMAN	Decreases Expression	[40]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Increases Expression	[35]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Decreases Expression	[41]
Intercellular adhesion molecule 1 (ICAM1)	OTTOIX77	ICAM1_HUMAN	Increases Expression	[42]
Fatty acid-binding protein, liver (FABP1)	OTR34ETM	FABPL_HUMAN	Increases Expression	[35]
Cathepsin B (CTSB)	OTP9G5QB	CATB_HUMAN	Decreases Expression	[43]
72 kDa type IV collagenase (MMP2)	OT5NIWA2	MMP2_HUMAN	Decreases Expression	[43]
Granzyme B (GZMB)	OTPPVIRS	GRAB_HUMAN	Affects Expression	[42]
Endoplasmic reticulum chaperone BiP (HSPA5)	OTFUIRAO	BIP_HUMAN	Decreases Expression	[35]
Parathyroid hormone-related protein (PTHLH)	OTI1JF13	PTHR_HUMAN	Decreases Expression	[44]
Bone morphogenetic protein 2 (BMP2)	OT23T37S	BMP2_HUMAN	Increases Expression	[39]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)	OT2D9DOV	TNR1A_HUMAN	Increases Expression	[29]
Integrin-binding sialoprotein (IBSP)	OT29944Y	SIAL_HUMAN	Increases Expression	[45]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Decreases Expression	[46]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Increases Expression	[29]
CD27 antigen (CD27)	OTH7NA58	CD27_HUMAN	Affects Expression	[29]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Decreases Phosphorylation	[40]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Decreases Phosphorylation	[40]
CD40 ligand (CD40LG)	OT75Z6A6	CD40L_HUMAN	Decreases Expression	[29]
Caspase-14 (CASP14)	OTKY93H9	CASPE_HUMAN	Decreases Expression	[29]
T-lymphocyte activation antigen CD80 (CD80)	OTJBLUQE	CD80_HUMAN	Increases Expression	[42]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Increases Expression	[35]
Tumor necrosis factor receptor superfamily member 3 (LTBR)	OT2HVZGV	TNR3_HUMAN	Increases Expression	[29]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[33]
T-lymphocyte activation antigen CD86 (CD86)	OTJCSBPC	CD86_HUMAN	Increases Expression	[42]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Expression	[47]
Caspase-2 (CASP2)	OTUDYSPP	CASP2_HUMAN	Affects Expression	[29]
DNA mismatch repair protein Msh2 (MSH2)	OT10H1AB	MSH2_HUMAN	Decreases Expression	[48]
Tumor necrosis factor ligand superfamily member 6 (FASLG)	OTZARCHH	TNFL6_HUMAN	Affects Expression	[29]
Caspase-4 (CASP4)	OTVQTV1L	CASP4_HUMAN	Increases Expression	[35]
DNA replication licensing factor MCM2 (MCM2)	OTGGORIQ	MCM2_HUMAN	Decreases Expression	[49]
Death-associated protein kinase 1 (DAPK1)	OTNCNUCO	DAPK1_HUMAN	Decreases Expression	[29]
Caspase-7 (CASP7)	OTAPJ040	CASP7_HUMAN	Increases Activity	[28]
Caspase-9 (CASP9)	OTD4RFFG	CASP9_HUMAN	Increases Activity	[29]
Caspase-6 (CASP6)	OTXLD3EC	CASP6_HUMAN	Increases Activity	[48]
BH3-interacting domain death agonist (BID)	OTOSHSHU	BID_HUMAN	Increases Expression	[29]
Transforming protein RhoA (RHOA)	OT6YOJ9N	RHOA_HUMAN	Decreases Geranoylation	[45]
Ras-related protein Rap-1A (RAP1A)	OT5RH6TI	RAP1A_HUMAN	Decreases Expression	[50]
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17)	OTTM6KRB	ADA17_HUMAN	Decreases Activity	[34]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Increases Expression	[35]
Tumor necrosis factor receptor superfamily member 9 (TNFRSF9)	OTNOM26L	TNR9_HUMAN	Decreases Expression	[29]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Decreases Expression	[29]
Bcl-2-like protein 1 (BCL2L1)	OTRC5K9O	B2CL1_HUMAN	Increases Expression	[29]
TNF receptor-associated factor 2 (TRAF2)	OT1MEZZN	TRAF2_HUMAN	Increases Expression	[29]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)	OT4SO7J4	BNIP3_HUMAN	Decreases Expression	[29]
Baculoviral IAP repeat-containing protein 1 (NAIP)	OTLA925F	BIRC1_HUMAN	Affects Expression	[29]
TNF receptor-associated factor 3 (TRAF3)	OT5TQBGV	TRAF3_HUMAN	Increases Expression	[29]
Baculoviral IAP repeat-containing protein 2 (BIRC2)	OTFXFREP	BIRC2_HUMAN	Decreases Expression	[29]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Expression	[29]
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD)	OTBOSJHO	TRADD_HUMAN	Increases Expression	[29]
Bcl-2-related protein A1 (BCL2A1)	OTWRYSNA	B2LA1_HUMAN	Decreases Expression	[29]
Bcl-2-like protein 2 (BCL2L2)	OTMKVO0J	B2CL2_HUMAN	Increases Expression	[29]
Bcl2-associated agonist of cell death (BAD)	OT63ERYM	BAD_HUMAN	Increases Expression	[29]
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25)	OTVZ7I3A	TNR25_HUMAN	Decreases Expression	[29]
BAG family molecular chaperone regulator 1 (BAG1)	OTRQNIA4	BAG1_HUMAN	Increases Expression	[29]
Bcl-2-like protein 10 (BCL2L10)	OTYXQJ3I	B2L10_HUMAN	Affects Expression	[29]
Baculoviral IAP repeat-containing protein 6 (BIRC6)	OTCQJAB0	BIRC6_HUMAN	Decreases Expression	[29]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)	OTW8V2V1	ABCG2_HUMAN	Increases Expression	[51]

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Breast Cancer	DCIMZA7	N. A.	Phase 1	[52]
Breast Cancer	DCVIW9B	N. A.	Phase 1	[53]

References

• [1] ClinicalTrials.gov (NCT00050011) Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy
• [2] Letrozole FDA Label
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5209).
• [4] In vitro cytotoxicity of zoledronate (nitrogen-containing bisphosphonate: NBP) and/or etidronate (non-NBP) in tumour cells and periodontal cells. Arch Oral Biol. 2013 Jun;58(6):628-37.
• [5] Giant Cell Tumor of Bone: Review of Current Literature, Evaluation, and Treatment Options. J Knee Surg. 2019 Apr;32(4):331-336.
• [6] Paget's Disease of Bone: Diagnosis and Treatment. Am J Med. 2018 Nov;131(11):1298-1303.
• [7] Current and future treatments of bone metastases. Expert Opin Emerg Drugs. 2008 Dec;13(4):609-27.
• [8] Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw. Clin Cancer Res. 2008 Apr 15;14(8):2387-95.
• [9] AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY CLINICAL PRACTICE GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS-2020 UPDATE. Endocr Pract. 2020 May;26(Suppl 1):1-46.
• [10] Aromatase inhibitors--theoretical concept and present experiences in the treatment of endometriosis. Zentralbl Gynakol. 2003 Jul-Aug;125(7-8):247-51.
• [11] Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro. Cancer Chemother Pharmacol. 2009 Oct;64(5):867-75.
• [12] Double-blind, randomised, multicentre endocrine trial comparing two letrozole doses, in postmenopausal breast cancer patients. Eur J Cancer. 1999 Feb;35(2):208-13.
• [13] Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer. Breast Cancer Res Treat. 2018 Nov;172(2):371-379.
• [14] Aromatase inhibition: translation into a successful therapeutic approach. Clin Cancer Res. 2005 Apr 15;11(8):2809-21. doi: 10.1158/1078-0432.CCR-04-2187.
• [15] Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes. Xenobiotica. 2009 Nov;39(11):795-802. doi: 10.3109/00498250903171395.
• [16] ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
• [17] Clomiphene citrate versus letrozole: molecular analysis of the endometrium in women with polycystic ovary syndrome. Fertil Steril. 2011 Oct;96(4):1051-6. doi: 10.1016/j.fertnstert.2011.07.1092.
• [18] Aromatase inhibition, testosterone, and seizures. Epilepsy Behav. 2004 Apr;5(2):260-3. doi: 10.1016/j.yebeh.2003.12.001.
• [19] Aromatase inhibitors: cellular and molecular effects. J Steroid Biochem Mol Biol. 2005 May;95(1-5):83-9. doi: 10.1016/j.jsbmb.2005.04.010.
• [20] Inhibition of estrogen receptor reduces connexin 43 expression in breast cancers. Toxicol Appl Pharmacol. 2018 Jan 1;338:182-190. doi: 10.1016/j.taap.2017.11.020. Epub 2017 Nov 24.
• [21] Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. Clin Cancer Res. 2005 Jul 15;11(14):5319-28. doi: 10.1158/1078-0432.CCR-04-2402.
• [22] Synergistic activity of letrozole and sorafenib on breast cancer cells. Breast Cancer Res Treat. 2010 Nov;124(1):79-88. doi: 10.1007/s10549-009-0714-5. Epub 2010 Jan 7.
• [23] Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology. 2006 Nov 10;228(1):24-32. doi: 10.1016/j.tox.2006.08.007. Epub 2006 Aug 12.
• [24] The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide. Exp Hematol. 2011 Jan;39(1):55-65.
• [25] Interleukin-19 as a translational indicator of renal injury. Arch Toxicol. 2015 Jan;89(1):101-6.
• [26] Transcriptomics hit the target: monitoring of ligand-activated and stress response pathways for chemical testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18.
• [27] Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity. Arch Toxicol. 2018 Jan;92(1):469-485.
• [28] Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. Eur Cytokine Netw. 2009 Sep;20(3):121-30. doi: 10.1684/ecn.2009.0159.
• [29] Effect of zoledronic acid on oral fibroblasts and epithelial cells: a potential mechanism of bisphosphonate-associated osteonecrosis. Br J Haematol. 2009 Mar;144(5):667-76. doi: 10.1111/j.1365-2141.2008.07504.x. Epub 2008 Nov 20.
• [30] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [31] Zoledronic acid is synergic with vinblastine to induce apoptosis in a multidrug resistance protein-1 dependent way: an in vitro study. Cell Biol Int. 2006 Mar;30(3):278-82.
• [32] Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. Biochem Biophys Res Commun. 2002 Mar 1;291(3):680-6. doi: 10.1006/bbrc.2002.6510.
• [33] Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells. Int J Cancer. 2009 Nov 1;125(9):2004-13. doi: 10.1002/ijc.24648.
• [34] The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE). J Bone Miner Res. 2004 Jan;19(1):147-54. doi: 10.1359/jbmr.2004.19.1.147.
• [35] Zoledronic acid-induced oxidative damage and endoplasmic reticulum stress-mediated apoptosis in human embryonic kidney (HEK-293) cells. J Biochem Mol Toxicol. 2022 Aug;36(8):e23083. doi: 10.1002/jbt.23083. Epub 2022 May 19.
• [36] Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase. Biochem Biophys Res Commun. 2007 Feb 23;353(4):921-5. doi: 10.1016/j.bbrc.2006.12.094. Epub 2006 Dec 21.
• [37] The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells. Br J Cancer. 2002 May 6;86(9):1479-86. doi: 10.1038/sj.bjc.6600297.
• [38] Expression profile and synthesis of different collagen types I, II, III, and V of human gingival fibroblasts, osteoblasts, and SaOS-2 cells after bisphosphonate treatment. Clin Oral Investig. 2010 Feb;14(1):51-8. doi: 10.1007/s00784-009-0312-2. Epub 2009 Jul 14.
• [39] The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro. Bone. 2004 Jan;34(1):112-23. doi: 10.1016/j.bone.2003.08.013.
• [40] Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro. Br J Cancer. 2003 Jun 16;88(12):1971-8. doi: 10.1038/sj.bjc.6600986.
• [41] Zoledronic acid effects interleukin-6 expression in hormone-independent prostate cancer cell lines. Int Braz J Urol. 2008 May-Jun;34(3):355-63; discussion 364. doi: 10.1590/s1677-55382008000300013.
• [42] Defective gammadelta T-cell function and granzyme B gene polymorphism in a cohort of newly diagnosed breast cancer patients. Exp Hematol. 2009 Jul;37(7):838-48. doi: 10.1016/j.exphem.2009.04.003. Epub 2009 May 14.
• [43] Effects of zoledronic acid on proteinase plasma levels in patients with bone metastases. Anticancer Res. 2006 Jan-Feb;26(1A):23-6.
• [44] Bone microenvironment-related growth factors, zoledronic acid and dexamethasone differentially modulate PTHrP expression in PC-3 prostate cancer cells. Horm Metab Res. 2005 Oct;37(10):593-601. doi: 10.1055/s-2005-870525.
• [45] Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition. Biochem J. 2004 Dec 15;384(Pt 3):591-8. doi: 10.1042/BJ20040380.
• [46] Differential effects of bisphosphonates on breast cancer cell lines. Cancer Lett. 2007 Feb 8;246(1-2):308-12. doi: 10.1016/j.canlet.2006.03.011. Epub 2006 Apr 18.
• [47] Zoledronic acid decreases mRNA six-transmembrane epithelial antigen of prostate protein expression in prostate cancer cells. J Endocrinol Invest. 2010 Apr;33(4):244-9. doi: 10.1007/BF03345787. Epub 2009 Nov 12.
• [48] Antitumor effects of aminobisphosphonates on renal cell carcinoma cell lines. J Urol. 2006 Nov;176(5):2255-61. doi: 10.1016/j.juro.2006.07.053.
• [49] The in vitro anti-tumour activity of zoledronic acid and docetaxel at clinically achievable concentrations in prostate cancer. Acta Oncol. 2007;46(5):669-77. doi: 10.1080/02841860600996447.
• [50] Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways. Cell Death Dis. 2013 Oct 24;4(10):e878. doi: 10.1038/cddis.2013.406.
• [51] In vitro evaluation of zoledronic acid resistance developed in MCF-7 cells. Anticancer Res. 2007 Nov-Dec;27(6B):4031-7.
• [52] ClinicalTrials.gov (NCT00412022) HOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in Premenopausal Patients With Breast Cancer.
• [53] ClinicalTrials.gov (NCT00107263) Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer