Details of the Drug Combinations

General Information of This Drug (ID: DM5EN79)

Drug Name
Levamisole   DM5EN79
Synonyms
Ketrax; LEVOMYSOL; Lepuron; Levamisol; Levamisolum; Levotetramisole; Tetramisol; Wormicid; Levamisole Base;Nilverm base; P00039; Vermisol 150; Dl-Tetramisol; Dl-Tetramisole; Ergamisol (TN); Ketrax (TN); L-Tetramisole; Levamisol [INN-Spanish]; Levamisole (INN); Levamisole [INN:BAN]; Levamisolum [INN-Latin]; TCMDC-125847; L(-)-Levamisole; L-2,3,5,6-Tetrahyro-6-phenylimidazo(2,1-b)thiazole; (-)-Tetramisole; (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole; (S)-(-)-Levamisole
Indication
Disease Entry ICD 11 Status REF
Parasitic infection 1D0Y-1G2Z Approved [1]
Colon cancer 2B90.Z Withdrawn from market [2]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

127 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Brincidofovir + Levamisole DCW0KP1 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Ribavirin-TP DC8T72W Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Lefaxin DCXTYVS Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Mebutamate DC98M6B Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Clindamycin DC2WGX7 Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Acetazolamide DCPRE37 Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Paromomycin DCGRV6O Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Diethylcarbamazine DCASURG Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Triamterene DCD5BA9 Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Dactinomycin DC55S19 Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + GYKI-52466 DCOQH2X GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + PMID28460551-Compound-2 DCQILBQ PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tacrine DCRF4CA Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Trioxsalen DCAUENM Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Methotrexate DCWVXS8 Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Dihydroergotamine DCB4ISZ Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Miglustat DCKCKM9 Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Vinblastine DCCHZOD Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Sivelestat DCZQORU Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Pazopanib HCl DCJXY2X Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Ezetimibe DCWXIZ5 Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Testosterone DCY4PQP Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Ramelteon DCLKG48 Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Acitretin DCRVSRK Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Dexmedetomidine DCCMG3O Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Pepstatin DCO29TS Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Dronedarone DC4REMZ Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Rifampin DC051HK Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + IT-141 DCUJFHR IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Trihexyphenidyl DCHQPIL Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + BHV-0223 DC0G0FF BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Metyrosine DCK0VF8 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Terameprocol DCYUUS4 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + SCH 727965 DCS7HOU SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Amodiaquine DCBXIL7 Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Flavonoid derivative 1 DCS48OE Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Itraconazole DC6Y9RS Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Ursodeoxycholic acid DC5LFY2 Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cinacalcet DC5DWHS Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Carglumic acid DCR1PLE Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Chlorzoxazone DCF7VDE Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Docetaxel DC2RSF3 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + ETHISTERONE DC230RT ETHISTERONE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cilastatin DCRECI6 Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + LY03004 DC3MFF2 LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Methoxsalen DC6JP7D Methoxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Aminosalicylic acid DC35QA0 Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + JZL195 DCT8A8P JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Sulfinpyrazone DCGH8OV Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Fibrates DCCDRIK Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + WAY-100635 DCY5VJS WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Armodafinil DC78U1R Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Sitagliptin DC2OWC7 Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Zaleplon DC27SKB Zaleplon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Mecamylamine DCRUMY4 Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + PHA-739358 DCEI2H7 PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Dichlorphenamide DCWK8LE Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Clopidogrel DCZDIK7 Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Diphenidol DCX7EW3 Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Pentamidine DC643A2 Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tolazoline DCB5CLO Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Procarbazine DC5WEBT Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Bosentan DCHAF3I Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + PFK-158 DCMQTDG PFK-158 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tolvaptan DCZL4CL Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Arfolitixorin DCRJTUS Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Triflupromazine DCFEIMP Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + BIO-300 DCGXXQ8 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Niclosamide DC4AWQK Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Norcisapride DC4CIFI Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tiagabine DCQMRB0 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Diazoxide DCSYQCO Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Fenoprofen DCBK7K0 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tamoxifen DC0286G Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + BRL-15572 DC9FG5A BRL-15572 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Imatinib DCJUZPX Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Linagliptin DCS6573 Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Pramipexole DCMJLSJ Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Bortezomib DCYCGEZ Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Methylene blue DCLRVOM Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Tropisetron DCX61ZW Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Mebendazole DCW1SKV Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Acamprosate DCG29GL Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Ethinyl estradiol DC79ITT Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Mesalazine DCAMU99 Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Artemisinin DCY63MD Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Topotecan DC0299H Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cefmenoxime DCHN8O6 Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Trimethobenzamide DCU26ST Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Enalaprilat DC7YUZ8 Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Maprotiline DCDKZGS Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Oxyphenbutazone DC5F42K Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole DCJLLMB 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Eptifibatide DCFPU58 Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Amiloride DCML91Y Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Bumetanide DC2463B Bumetanide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Valproic Acid DCBE9V6 Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Desoxycorticosterone pivalate DCDAAPR Desoxycorticosterone pivalate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Chloroquine DCGUHNS Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Hyodeoxycholic acid DCENKJ9 Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Asenapine DCILJUX Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Naltrexone DCTA7EJ Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Loperamide DCGGXY4 Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Spironolactone DCJ5TGY Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Maraviroc DCZ076Q Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Chlormezanone DCPG53K Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Endoxifen DCQ22XO Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Hydralazine DC6VDWG Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Fosfomycin DCIRC78 Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Doxorubicin DCPAV25 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Nitisinone DCYDQFG Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Sumatriptan DCT8T0Q Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Olmesartan medoxomil DC3AL72 Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Rufinamide DCAVQUZ Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + FORMESTANE DCD9OS7 FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Vorinostat DCC2PTI Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Estramustine DCOP6EP Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cerivastatin DCBUR7M Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Metaxalone DCN5KZX Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Busulfan DCA2053 Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Hydroxychloroquine DCS6DUO Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + AS-1949490 DC8V6YM AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Azatadine DCUN30U Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Nitrosoglutathione DCQZE65 Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cytarabine DCHNGTY Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Cilostazol DCURJ7R Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + L-165041 DCTD6E9 L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 127 DrugCom(s)
1 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Levamisole + Inosine pranobex DCGQ05Z Inosine pranobex Coronavirus Disease 2019 (COVID-19) [4]
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References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7210).
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT04383717) Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial. U.S. National Institutes of Health.