Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAHJEF)

Drug Name
Betamethasone Drug Info
Synonyms
betamethasone; 378-44-9; Betadexamethasone; Flubenisolone; Betamethazone; Rinderon; Visubeta; Celestene; Betnelan; Betapredol; Betacortril; Betacorlan; Methazon; Betsolan; Betamamallet; Hormezon; Betasolon; Betametasone; Cidoten; Bebate; Bedifos; Becort; beta-Methasone; Desacort-Beta; Rinderon A; beta-Methasone alcohol; Betametasona; Betafluorene; Betamethasonum; Celestone; Betamethasone cream; Betamethasone alcohol; Betametasone [DCIT]; 9alpha-Fluoro-16beta-methylprednisolone; Celestone Syrup and Tablets; Celeston; Celestona; Cellestoderm; Luxiqo; Betamethasone Base; Betamethasone Valearate; Betamethasonvalerat Mikron; LT00441022; SCH 4831; Beta-Methasone; Beta-Methasone alcohol; Betametasona [INN-Spanish]; Betamethasonum [INN-Latin]; Betnovate (TN); Celestone (TN); Diprolene (TN); Diprosone (TN); Lotrisone (TN); Rinderon (TN); SCH-4831; Betamethasone (JP15/USP/INN); Betamethasone [USAN:BAN:INN:JAN]; Betamethasone [USAN:INN:BAN:JAN]; Celestone, Betadexamethasone, Flubenisolone, Sch-4831, NCS-39470, Betamethasone; 1,4-Pregnadiene-3,20-dione-9alpha-fluoro-16 beta-methyl-11 beta,17alpha,21-triol; 16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione; 9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione; 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; 9-Fluoro-16beta-methylprednisolone; 9-alpha-Fluoro-16-beta-methylprednisolone; 9alpha-Fluoro-16 beta-methyl-prednisolone; Betamethasone sodium phosphate
Indication
Disease Entry ICD 11 Status REF
Acute adrenal insufficiency Approved [1]
Addison disease 5A74.0 Approved [1]
Allergic rhinitis CA08.0 Approved [1]
Angioedema 4A00.15 Approved [1]
Aspiration pneumonitis Approved [1]
Autoimmune haemolytic anaemia 3A20 Approved [1]
Bursitis Approved [1]
Cerebral edema 8D60.1 Approved [1]
Congenital adrenal hyperplasia 5A71.01 Approved [1]
Crohn disease DD70 Approved [1]
Dermatitis herpetiformis EB44 Approved [1]
Diamond-Blackfan anemia Approved [1]
Disorder of orbital region Approved [1]
Epicondylitis Approved [1]
Erythema multiforme Approved [1]
Exanthem Approved [1]
Granuloma annulare Approved [1]
Inflammation 1A00-CA43.1 Approved [2]
Inflammatory bowel disease DD72 Approved [1]
Miliary tuberculosis Approved [1]
Multiple sclerosis 8A40 Approved [1]
Mycosis fungoides 2B01 Approved [1]
Primary cutaneous T-cell lymphoma Approved [1]
Psoriasis EA90 Approved [1]
Psoriatic arthritis FA21 Approved [1]
Rheumatic heart disease Approved [1]
Sarcoidosis 4B20.5 Approved [1]
Scalp dermatosis Approved [1]
Serum sickness Approved [1]
Severe asthma CA23 Approved [1]
Skin disease EA00-EM0Z Approved [1]
Systemic lupus erythematosus 4A40.0 Approved [1]
Tinea corporis 1F28.Y Approved [1]
Tinea cruris 1F28.3 Approved [1]
Acquired thrombocytopenia Investigative [1]
Asthma CA23 Investigative [1]
Beta-thalassemia major Investigative [1]
Classic Hodgkin lymphoma Investigative [1]
Follicular lymphoma 2A80 Investigative [1]
Rheumatoid arthritis FA20 Investigative [1]
Synovitis Investigative [1]
Tinea pedis 1F28.2 Investigative [1]
Trichinellosis Investigative [1]
Therapeutic Class
Antiinflammatory Agents
Cross-matching ID
PubChem CID
9782
ChEBI ID
CHEBI:3077
CAS Number
CAS 378-44-9
TTD Drug ID
DMAHJEF
VARIDT Drug ID
DR01392
ACDINA Drug ID
D00879

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [10]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [11]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [12]
Fluticasone DMGCSVF Allergic rhinitis CA08.0 Approved [13]
Betamethasone Valerate DMMIAXO Dermatological disease DA24.Y Approved [11]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [11]
Deflazacort DMV0RNS Duchenne dystrophy 8C70 Approved [11]
Prednisone DM2HG4X Acute asthma CA23 Approved [14]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [15]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [16]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Selenium DM25CGV N. A. N. A. Approved [35]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [39]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [41]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [17]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Folic Acid DMEMBJC Colorectal carcinoma Approved [20]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [19]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [19]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [21]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [19]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [22]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Frataxin, mitochondrial (FXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [24]
Molsidomine DM9MA8O Angina pectoris BA40 Approved [8]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [25]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [26]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [27]
Ethanol DMDRQZU Chronic pain MG30 Approved [28]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [29]
Deferiprone DMS2M7O Beta thalassemia 3A50.2 Approved [8]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [30]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mineralocorticoid receptor (NR3C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [42]
Testosterone DM7HUNW Hot flushes GA30 Approved [43]
Triamcinolone DM98IXF Acute adrenal insufficiency Approved [9]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [44]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [45]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [46]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [9]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [9]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [47]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [9]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 3 (CCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [49]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [52]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [53]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [6]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [48]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 4 (CCL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [49]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [53]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [55]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [25]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [46]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [56]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [48]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [33]
Gefitinib DM15F0X Colon adenocarcinoma Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [59]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [60]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Early growth response protein 1 (EGR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [67]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [49]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [70]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Testosterone DM7HUNW Hot flushes GA30 Approved [74]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [74]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [75]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [78]
Ethanol DMDRQZU Chronic pain MG30 Approved [79]
Oxymetholone DMFXUT8 Aplastic anemia 3A70 Approved [80]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucocorticoid receptor (NR3C1) TTYRL6O GCR_HUMAN Agonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Regulation of Drug Effects [5]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [6]
C-C motif chemokine 3 (CCL3) OTW2H3ND CCL3_HUMAN Gene/Protein Processing [6]
C-C motif chemokine 4 (CCL4) OT6B8P25 CCL4_HUMAN Gene/Protein Processing [6]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Gene/Protein Processing [7]
Frataxin, mitochondrial (FXN) OTE9U09A FRDA_HUMAN Gene/Protein Processing [8]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Gene/Protein Processing [9]
Mineralocorticoid receptor (NR3C2) OT0F2V2Z MCR_HUMAN Gene/Protein Processing [9]
Vascular endothelial growth factor A, long form OTIM9MZ3 VEGFA_HUMAN Gene/Protein Processing [6]

References

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