Details of the Drug

General Information of Drug (ID: DMRHGI9)

• Drug Name: Cisplatin
• Synonyms: Abiplatin; Biocisplatinum; Briplatin; Cismaplat; Cisplatine; Cisplatino; Cisplatinum; Cisplatyl; Citoplationo; Lederplatin; Neoplatin; Plastin; Platamine; Platidiam; Platinoxan; Randa; Cis-DDP; Cis-Diamminedichloroplatinum; Peyrone's chloride; Peyrone's salt; Cis-Dichlorodiammineplatinum(II); Cis-[PtCl2(NH3)2]; Cis-diamminedichloridoplatinum(II); Trans-diamminedichloridoplatinum(II); (SP-4-1)-diamminedichloridoplatinum; (SP-4-1)-diamminedichloroplatinum; (SP-4-2)-diamminedichloridoplatinum; (SP-4-2)-diamminedichloroplatinum; Cisplatin (Chemotherapy)

Indication

Disease Entry	ICD 11	Status	REF
Adenocarcinoma	2D40	Approved	[1]
Anterior urethra cancer	N.A.	Approved	[1]
Carcinoma	2A00-2F9Z	Approved	[1]
Central nervous system neoplasm	N.A.	Approved	[1]
Epithelial ovarian cancer	2B5D	Approved	[1]
Epithelioid mesothelioma	2F10	Approved	[1]
Esophageal squamous cell carcinoma	2E60.1	Approved	[1]
Extragonadal germ cell tumor	N.A.	Approved	[1]
Gastric intestinal type adenocarcinoma	N.A.	Approved	[1]
Gastroesophageal junction adenocarcinoma	2B71	Approved	[1]
Lung cancer	2C25.0	Approved	[1]
Non-small-cell lung cancer	2C25.Y	Approved	[1]
Plasma cell myeloma	2A83.1	Approved	[1]
Posterior urethra cancer	N.A.	Approved	[1]
Primary peritoneal carcinoma	N.A.	Approved	[1]
Primitive neuroectodermal tumor	N.A.	Approved	[1]
Sarcomatoid mesothelioma	N.A.	Approved	[1]
Small-cell lung cancer	2C25.Y	Approved	[1]
Solid tumour/cancer	2A00-2F9Z	Approved	[2]
Testicular germ cell tumor	N.A.	Approved	[1]
Urinary bladder neoplasm	N.A.	Approved	[1]
Osteosarcoma	2B51	Phase 2	[3]
Gastric cancer	2B72	Investigative	[1]

• Therapeutic Class: Anticancer Agents
• Affected Organisms: Humans and other mammals
• ATC Code:
  L01XA01: Cisplatin
  L01XA: Platinum compounds
  L01X: OTHER ANTINEOPLASTIC AGENTS
  L01: ANTINEOPLASTIC AGENTS
  L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 300.05
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 0
  Hydrogen Bond Donor Count; 2
  Hydrogen Bond Acceptor Count; 2
• ADMET Property:
  BDDCS Class: Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 1: high solubility and high permeability [4]
  Elimination: 2.3% of drug is excreted from urine in the unchanged form [4]
  Half-life: The concentration or amount of drug in body reduced by one-half in 30 minutes (platinum in plasma), and more than 5 days (complexes between albuminutes and the platinum) [5]
  MRTD: The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 4.74882 micromolar/kg/day [6]
  Water Solubility: The ability of drug to dissolve in water is measured as 2.53 mg/mL [4]

Adverse Drug Reaction (ADR)

ADR Term	Variation	Related DOT	DOT ID	REF
Cell-mediated cytotoxicity	Not Available	PTK6	OT7NWIQ0	[7]
Electrolyte imbalance	Not Available	BGLAP	OTK1YLWQ	[7]
Electrolyte imbalance	Not Available	PTH1R	OTQF5ZAK	[7]
Hypersensitivity	Not Available	YBT1	OTPQCBKA	[7]
Nephropathy toxic	Not Available	HEXA	OT48T897	[7]
Neutropenia	rs4627050	PTPN5	OT2H1KDK	[8]
Neutropenia	rs2406342	ZNF236	OTXXMGJA	[8]
Ototoxicity	rs2075252	LRP2	OTZ6W681	[9]
Renal failure acute	Not Available	NCOA1	OTLIUJQD	[7]
Renal failure acute	Not Available	ACOX1	OTM0A0DY	[7]
Renal failure acute	Not Available	RXRA	OTP1TBDM	[7]

• Chemical Identifiers:
  Formula: Cl2H6N2Pt
  IUPAC Name: azane;dichloroplatinum
  Canonical SMILES: N.N.Cl[Pt]Cl
  InChI: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
  InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
• Cross-matching ID:
  PubChem CID: 5702198
  CAS Number: 15663-27-1
  UNII: Q20Q21Q62J
  DrugBank ID: DB00515
  TTD ID: D0U5HU
  VARIDT ID: DR00291
  INTEDE ID: DR0332
  ACDINA ID: D00950
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human Deoxyribonucleic acid (hDNA)	TTUTN1I	NOUNIPROTAC	Modulator	[10]

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
High affinity copper uptake protein 1 (SLC31A1)	DTP8L4F	COPT1_HUMAN	Substrate	[11]
Copper-transporting ATPase 2 (ATP7B)	DT206GF	ATP7B_HUMAN	Substrate	[12]
Multidrug resistance-associated protein 6 (ABCC6)	DT582KR	MRP6_HUMAN	Substrate	[13]
Probable low affinity copper uptake protein 2 (SLC31A2)	DT8Q56F	COPT2_HUMAN	Substrate	[14]
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[15]
Organic cation transporter 1 (SLC22A1)	DTT79CX	S22A1_HUMAN	Substrate	[16]
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[17]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[18]
Organic cation transporter 2 (SLC22A2)	DT9IDPW	S22A2_HUMAN	Substrate	[19]
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[20]

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 2E1 (CYP2E1)	DEVDYN7	CP2E1_HUMAN	Substrate	[21]
Glutathione S-transferase alpha-1 (GSTA1)	DE4ZHS1	GSTA1_HUMAN	Substrate	[22]
Quinone reductase 1 (NQO1)	DENP5RY	NQO1_HUMAN	Substrate	[23]
Glutathione S-transferase pi (GSTP1)	DEK6079	GSTP1_HUMAN	Substrate	[24]
Metallothionein-1A (MT1A)	DE5ME8A	MT1A_HUMAN	Substrate	[25]
Myeloperoxidase (MPO)	DEA3U9Y	PERM_HUMAN	Substrate	[26]
Metallothionein-2A (MT2A)	DEFKGT7	MT2_HUMAN	Substrate	[25]
Glutathione S-transferase mu-1 (GSTM1)	DEYZEJA	GSTM1_HUMAN	Substrate	[24]
Superoxide dismutase 1 (SOD1)	DEUTDON	SODC_HUMAN	Substrate	[23]
Glutathione S-transferase theta-1 (GSTT1)	DE3PKUG	GSTT1_HUMAN	Substrate	[24]
Glutathione S-transferase alpha-4 (GSTA4)	DEH7XYP	GSTA4_HUMAN	Substrate	[27]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8)	OTX1DWEF	DHB8_HUMAN	Gene/Protein Processing	[28]
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4)	OTQK3M9X	ABHD4_HUMAN	Gene/Protein Processing	[29]
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)	OTG2T749	CP24A_HUMAN	Gene/Protein Processing	[28]
1,4-alpha-glucan-branching enzyme (GBE1)	OTK2N05B	GLGB_HUMAN	Gene/Protein Processing	[30]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2)	OT5I4Y9K	PLCB_HUMAN	Gene/Protein Processing	[30]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5)	OTY829Z3	ABHD5_HUMAN	Gene/Protein Processing	[31]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3)	OTR4990X	PLPL3_HUMAN	Gene/Protein Processing	[28]
1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACCS)	OTHIHI9D	1A1L1_HUMAN	Gene/Protein Processing	[31]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (PLCB2)	OTPAHDGO	PLCB2_HUMAN	Gene/Protein Processing	[30]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (PLCB4)	OTPA0QHW	PLCB4_HUMAN	Gene/Protein Processing	[28]

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC1; GDSC2	2.3241	5.5903	1.2774	14.2644
EW-22	GDSC1; GDSC2	-0.382	2.5109	-0.5312	33.459
A-673	GDSC1; GDSC2	0.112	2.7652	-0.0464	29.1509
EW-3	GDSC1; GDSC2	0.1127	5.0511	-0.7678	32.1733
ES1	GDSC1; GDSC2	0.2725	2.9919	0.078	27.8984
ES8	GDSC1; GDSC2	0.4135	2.7425	0.2852	26.3498
ES7	GDSC1; GDSC2	0.5347	2.4129	0.4715	24.9789
SK-ES-1	GDSC1; GDSC2	0.6603	3.4663	0.3765	24.895
EW-11	GDSC1; GDSC2	0.8378	4.4599	0.2331	24.8621
ES4	GDSC1; GDSC2	1.0444	3.5365	0.7746	21.4407
SK-PN-DW	GDSC1; GDSC2	1.2829	4.4011	0.7309	20.7282
HuO9	GDSC1; GDSC2	1.3473	3.5951	1.0866	18.7219
TC-71	GDSC1; GDSC2	1.6895	3.7336	1.4131	15.778
CADO-ES1	GDSC1; GDSC2	1.7574	3.5729	1.5399	14.888
ES5	GDSC1	1.787	7.0303	0.0726	25.3399
EW-13	GDSC1; GDSC2	1.9561	5.9251	0.76	18.1953
EW-1	GDSC1; GDSC2	2.1172	5.6121	1.0649	16.0675
EW-7	GDSC1; GDSC2	2.1429	5.2491	1.259	14.9538
HOS	GDSC1; GDSC2	2.215	4.3324	1.7418	12.1578
CHSA0108	GDSC1	2.2551	4.7941	1.1948	10.855
EW-16	GDSC1; GDSC2	2.4937	5.3293	1.5656	12.1696
NY	GDSC1; GDSC2	2.6385	6.6867	1.0408	14.5699
MHH-ES-1	GDSC1; GDSC2	2.6583	4.7271	2.0112	9.2291
U2OS	GDSC1; GDSC2	2.6772	5.0755	1.8633	9.9741
MG-63	GDSC1; GDSC2	2.6946	7.4594	0.7096	16.1564
CAL-72	GDSC1; GDSC2	3.2037	5.5298	2.1179	7.0399
G-292 clone A141B1	GDSC1; GDSC2	3.3895	5.6916	2.1929	6.1397
SJSA-1	GDSC1; GDSC2	3.5269	6.1515	2.0742	6.4655
H-EMC-SS	GDSC1; GDSC2	3.6313	7.8397	1.3155	10.4069
EW-18	GDSC1; GDSC2	3.6403	6.3949	2.0421	6.3765
CHSA8926	GDSC1; GDSC2	3.6572	7.6996	1.4058	9.8512
SaOS-2	GDSC1; GDSC2	3.7093	7.7142	1.4397	9.542
ES6	GDSC1; GDSC2	3.8572	7.0429	1.8865	6.7464
NOS-1 [Human HNSCC]	GDSC1; GDSC2	4.0166	5.8198	2.5937	2.595
HuO-3N1	GDSC1; GDSC2	4.1431	8.3108	1.4744	8.3729
EW-24	GDSC1; GDSC2	4.284	7.8146	1.818	6.2281
CAL-78	GDSC1; GDSC2	4.4189	9.0351	1.3199	8.6186
CHSA0011	GDSC1	5.91	13.1116	0.3795	11.8262
SK-ES-1	CTRP2	6.8962	8.2944	5.5249	0.9873
Hs 822.T	CTRP2	6.9311	14.2908	2.6349	12.5158
A-673	CTRP2	7.003	8.9667	5.2838	1.7521
CAL-78	CTRP2	7.4001	11.7074	4.2475	5.2992
TC71	CTRP2	7.4111	8.5767	5.6569	0.259
SK-N-MC	CTRP2	7.5989	8.7454	5.6696	0.1724
U2OS	CTRP2	7.6268	9.9167	5.2136	1.3755
MG-63	CTRP2	7.9864	9.9019	5.3944	0.5945
SW1353	CTRP2	8.3015	9.8004	5.5592	0.1632
MHH-ES-1	CTRP2	8.3551	10.0612	5.4867	0.2573
SaOS-2	CTRP2	8.4011	10.5363	5.3288	0.5488
Hs 888.T	CTRP2	8.4196	21.5479	0.1721	18.3486
HOS	CTRP2	8.4782	9.7885	5.626	0.0665
G-292 clone A141B1	CTRP2	8.7582	14.4558	3.8276	5.1804
SJSA-1	CTRP2	10.5625	26.0102	-0.4701	16.9676

Cancer Drug Sensitivity Data Curated from 313 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MEC1	CTRP2	7.4102	9.2839	5.3714	1.0434
JK1	CTRP2	7.4355	9.5449	4.34	0.5454
JM1	GDSC1	1.9877	3.4551	1.8274	14.5753
JM1	CTRP2	7.0941	10.5168	4.611	4.2748
SCC-3	GDSC2	-1.7652	-0.3656	-1.7666	41.2401
Namalwa	GDSC1; GDSC2	-0.1738	1.6444	-0.1977	31.0776
MV4-11	GDSC1; GDSC2	-0.0677	2.2589	-0.1506	30.4007
697	GDSC1; GDSC2	-0.0519	1.3992	-0.0599	29.927
Hs 445	GDSC1; GDSC2	0.2365	2.5462	0.0325	23.2699
SUP-M2	GDSC1; GDSC2	0.4444	1.8038	0.4327	25.5464
HEL	GDSC1	0.522	1.8646	0.5097	28.819
L-540	GDSC1; GDSC2	0.6304	2.4312	0.5712	24.1133
NALM-6	GDSC1; GDSC2	0.7362	2.3556	0.6933	23.1015
SR	GDSC1; GDSC2	0.8565	2.3531	0.821	22.0023
NKM-1	GDSC1; GDSC2	0.8965	3.7622	0.5428	23.1486
MOLM-13	GDSC1; GDSC2	0.9152	2.9725	0.6439	17.2051
RPMI-8402	GDSC1; GDSC2	1.0496	3.0213	0.9172	20.7402
BV-173	GDSC1; GDSC2	1.0684	2.9079	0.962	20.4519
LC4-1	GDSC1; GDSC2	1.083	3.1548	0.9221	20.5792
HAL-01	GDSC1; GDSC2	1.1022	3.5333	0.8386	20.9004
KE-37	GDSC1; GDSC2	1.1146	2.7464	1.0422	19.885
Karpas-231	GDSC1; GDSC2	1.1217	2.5703	1.0764	19.6977
RS4;11	GDSC1; GDSC2	1.1532	3.4444	0.9205	20.3013
ML-2	GDSC1; GDSC2	1.1845	2.9804	1.0729	19.4486
KOPN-8	GDSC1; GDSC2	1.2377	3.2474	1.0672	19.2557
SUP-B15	GDSC1; GDSC2	1.2799	3.2017	1.1251	18.8077
RCH-ACV	GDSC1	1.2898	3.2774	1.1162	21.8024
P12-Ichikawa	GDSC1; GDSC2	1.3005	3.0455	1.1848	18.4405
CRO-AP2	GDSC1	1.3682	4.3368	0.8468	22.9558
NB4	GDSC1	1.3846	2.6124	1.3507	20.0732
NU-DUL-1	GDSC1	1.3984	3.1164	1.275	20.4133
WIL2 NS	GDSC1; GDSC2	1.3992	3.3679	1.2108	17.913
SU-DHL-8	GDSC1; GDSC2	1.541	3.2288	1.2225	11.5599
P30/OHK	GDSC1; GDSC2	1.5796	2.852	1.5251	15.6841
HC-1	GDSC1; GDSC2	1.6055	3.7256	1.3248	16.5405
Jurkat	GDSC1; GDSC2	1.6199	3.3004	1.4703	15.7744
BL-41	GDSC1; GDSC2	1.6235	2.4073	1.6174	15.0749
SU-DHL-5	GDSC1; GDSC2	1.6345	3.1484	1.5247	15.4563
JVM-3	GDSC1; GDSC2	1.652	4.5333	1.0691	17.6546
A3/Kawakami	GDSC1; GDSC2	1.6548	1.9784	1.6548	14.7705
EoL-1	GDSC1; GDSC2	1.6763	2.7177	1.6477	14.7084
VL51	GDSC1; GDSC2	1.7119	4.2794	1.2348	16.5896
JURL-MK1	GDSC1; GDSC2	1.7185	5.3824	0.7715	18.9443
SKM-1	GDSC1	1.7266	6.5736	0.2304	24.7873
OCI-Ly19	GDSC1	1.7364	4.5109	1.1669	19.5147
H9	GDSC1; GDSC2	1.7649	4.3379	1.2675	16.2279
NOMO-1	GDSC1; GDSC2	1.809	3.8374	1.5061	14.8553
CML-T1	GDSC1; GDSC2	1.8399	3.1026	1.7587	13.5028
MOLM-16	GDSC1	1.8939	4.0845	1.2029	12.167
HL-60	GDSC1; GDSC2	1.9268	3.5208	1.7408	13.2373
P32/ISH	GDSC1; GDSC2	1.9877	3.4433	1.8309	12.5565
Granta-519	GDSC1; GDSC2	2.0079	3.9725	1.6695	13.2822
DoHH2	GDSC1	2.0091	4.026	1.6501	18.8639
A4/Fukuda	GDSC1; GDSC2	2.0962	4.4492	1.5686	13.4811
MOLT-4	GDSC1; GDSC2	2.1269	4.9356	1.386	14.3348
Reh	GDSC1; GDSC2	2.1295	3.4748	1.9759	11.2876
OCI-AML-2	GDSC1; GDSC2	2.1377	4.528	1.5776	13.2881
SUP-HD1	GDSC1; GDSC2	2.1512	5.2227	1.2795	14.8176
GR-ST	GDSC1; GDSC2	2.1605	6.7527	0.5632	18.5408
MOLT-16	GDSC1; GDSC2	2.1788	3.263	2.09	10.5392
AMO1	GDSC1; GDSC2	2.1829	4.3726	1.6913	12.5347
RPMI-6666	GDSC1; GDSC2	2.2354	5.1554	1.3944	13.9265
DEL	GDSC1; GDSC2	2.2513	4.0166	1.9109	11.1524
KCL-22	GDSC1; GDSC2	2.2547	5.7743	1.1227	15.3144
OCI-AML-5	GDSC1; GDSC2	2.2576	4.7619	1.5965	12.7759
L-428	GDSC1; GDSC2	2.2985	4.8981	1.5758	12.7485
CTV-1	GDSC1; GDSC2	2.3701	5.5081	1.361	13.6679
CTB-1	GDSC1	2.3897	5.5111	1.3785	15.6424
RPMI-8866	GDSC1; GDSC2	2.401	3.8856	2.1218	9.5228
MOLP-8	GDSC1; GDSC2	2.4865	4.7888	1.4	7.3612
MHH-CALL-2	GDSC1; GDSC2	2.5061	5.9888	1.2597	13.7892
GDM-1	GDSC1; GDSC2	2.5607	5.69	1.456	12.5561
LAMA-84	GDSC1; GDSC2	2.6103	5.1103	1.7825	10.6239
QIMR-WIL	GDSC1	2.6252	3.6984	2.4337	8.2346
ALL-SIL	GDSC1; GDSC2	2.6294	4.4195	2.1261	8.7044
DB	GDSC1; GDSC2	2.6624	8.0092	0.4083	17.7914
ATN-1	GDSC1; GDSC2	2.7914	4.9372	2.0386	8.6626
CMK	GDSC1	2.7969	3.7074	2.6117	6.4485
EHEB	GDSC1	2.8176	5.6683	1.2327	8.7454
Loucy	GDSC1; GDSC2	2.8178	6.0038	1.5408	11.3231
KG-1	GDSC1; GDSC2	2.8332	6.9652	1.0786	13.8003
ARH-77	GDSC1; GDSC2	2.9455	4.5259	2.3832	6.3009
OCI-AML-3	GDSC1; GDSC2	2.9926	6.7333	1.3346	11.9603
Karpas-299	GDSC1; GDSC2	3.0121	5.1197	2.1534	7.373
KMS-28BM	CTRP2	3.03	5.3579	2.753	15.431
U-698-M	GDSC1; GDSC2	3.0803	6.0878	1.7328	9.5194
OCI-M1	GDSC1; GDSC2	3.1165	4.9304	2.3407	6.0362
ROS-50	GDSC1	3.1207	5.1044	1.739	4.4119
Daudi	GDSC1; GDSC2	3.1567	6.901	1.3929	11.1925
EB2	GDSC1; GDSC2	3.1804	4.3432	2.689	3.9189
BALL-1	GDSC1; GDSC2	3.1927	5.79	1.9786	7.8464
CCRF-CEM	GDSC1; GDSC2	3.2092	5.9066	1.9345	8.0489
JSC-1	GDSC1; GDSC2	3.2447	6.5939	1.6211	9.6989
MM1.S	GDSC1; GDSC2	3.2563	5.2828	2.2863	5.9596
ALL-PO	GDSC1; GDSC2	3.2695	7.8378	1.0202	12.9191
WSU-NHL	GDSC1; GDSC2	3.2744	6.0428	1.9217	7.9485
Mono-Mac-6	GDSC1; GDSC2	3.324	6.9798	1.4947	10.1924
L-363	GDSC1; GDSC2	3.331	7.8248	1.078	12.4479
SU-DHL-10	GDSC1; GDSC2	3.3618	9.2528	-0.1258	13.8303
Ku812	GDSC1; GDSC2	3.3817	5.0257	2.5194	4.3352
Ramos.2G6.4C10	GDSC1; GDSC2	3.4028	4.938	2.5803	3.9427
HH [Human lymphoma]	GDSC1; GDSC2	3.4083	5.0742	2.5167	4.2846
SUP-T1	GDSC1; GDSC2	3.4209	6.1351	1.9969	7.1555
THP-1	GDSC1	3.4446	4.8423	2.6614	3.9285
CESS	GDSC1; GDSC2	3.5249	6.9392	1.6795	8.6646
KY821	GDSC1; GDSC2	3.5407	5.7417	2.2892	5.2353
KMS-12-BM	GDSC1; GDSC2	3.5477	5.8289	2.2513	5.4299
KMOE-2	GDSC1; GDSC2	3.555	5.601	2.3704	4.7502
TK [Human B-cell lymphoma]	GDSC1; GDSC2	3.592	5.2088	2.593	3.4317
DND-41	GDSC1; GDSC2	3.6193	6.0583	2.193	5.5871
Karpas-1106P	GDSC1; GDSC2	3.6277	6.2717	2.0935	6.1205
VAL	GDSC1; GDSC2	3.6296	6.9838	1.7406	8.0741
IM-9	GDSC1; GDSC2	3.6382	9.0537	0.7152	13.5833
GA-10	GDSC1; GDSC2	3.6687	6.9566	1.7849	7.7364
NCI-H929	GDSC1; GDSC2	3.6968	6.8967	1.8365	7.3853
KMS-11	GDSC1	3.7073	7.9393	1.3261	11.7276
PF-382	GDSC1; GDSC2	3.7876	5.9732	2.3615	4.2847
JVM-2	CTRP2	3.8086	6.1055	3.5875	15.6706
EM-2	GDSC1; GDSC2	3.8101	6.1434	2.2944	4.6053
SU-DHL-6	GDSC1; GDSC2	3.8303	5.9669	2.3954	4.0108
MEG-01	GDSC1; GDSC2	3.8386	7.1604	1.8144	7.1848
JeKo-1	GDSC1	3.8812	5.7607	2.5313	3.6787
MHH-PREB-1	GDSC1; GDSC2	3.8953	6.1547	2.3503	4.1242
OCI-Ly7	GDSC1	3.9226	5.3906	2.7351	2.3428
Raji	GDSC1; GDSC2	3.9367	7.341	1.7989	7.0534
ST486	GDSC1; GDSC2	3.9384	6.4769	2.224	4.724
BE-13	GDSC1; GDSC2	3.9676	6.3905	2.2867	4.3244
HT	GDSC1	3.9828	5.6139	2.6687	2.6227
JVM-2	GDSC1; GDSC2	4.0248	8.6008	1.2429	9.8794
SUP-T11	CTRP2	4.0282	7.0712	3.0961	11.1283
L-1236	GDSC1; GDSC2	4.0353	7.4169	1.8342	6.6489
MC116	GDSC1	4.0675	5.5837	2.7354	2.0712
YT	GDSC1; GDSC2	4.0856	7.2189	1.9674	5.8191
MN-60	GDSC1; GDSC2	4.101	6.3887	2.3791	3.5739
HDLM-2	GDSC1; GDSC2	4.1315	7.7699	1.7312	7.0072
SK-MM-2	GDSC1; GDSC2	4.1337	6.4041	2.3935	3.4385
RPMI-8226	GDSC1; GDSC2	4.1338	8.0122	1.6142	7.6367
MY-M12	GDSC1	4.2254	5.9665	2.6552	2.7477
P31/FUJ	GDSC1; GDSC2	4.2325	6.5506	2.3887	3.2899
Farage	GDSC1	4.2682	5.634	2.8267	1.2602
U266B1	GDSC1; GDSC2	4.3044	7.767	1.8553	5.9878
MLMA	GDSC1; GDSC2	4.3063	9.8601	0.8325	11.4102
OPM-2	GDSC1; GDSC2	4.3767	6.7901	2.3682	3.1538
Karpas-45	GDSC1; GDSC2	4.3866	6.0624	2.7042	1.4949
Karpas-422	GDSC1; GDSC2	4.3936	9.306	1.1692	9.4679
RC-K8	GDSC1; GDSC2	4.3948	7.6017	1.9966	5.0623
K-562	GDSC1; GDSC2	4.3972	7.2818	2.1504	4.2471
CA46	GDSC1; GDSC2	4.45	6.456	2.5652	2.0638
LP-1	GDSC1	4.5421	6.0369	2.796	1.0754
MOLT-13	GDSC1; GDSC2	4.6067	7.7489	2.0656	4.3265
KM-H2	GDSC1; GDSC2	4.6548	9.9308	1.0516	9.5403
Kasumi-1	GDSC1	4.6617	9.8482	1.0967	10.6662
JJN-3	GDSC1; GDSC2	4.6721	7.089	2.4091	2.5044
Jiyoye	GDSC1; GDSC2	4.6761	9.1536	1.4429	7.4581
BC-1	GDSC1; GDSC2	4.7041	9.0942	1.4907	7.1542
DG-75	GDSC1; GDSC2	4.7305	7.8102	2.1148	3.8721
DoHH2	CTRP2	4.7731	7.5416	4.0831	11.0787
EJM	GDSC1; GDSC2	4.7895	7.0782	2.4798	2.0178
SUP-B8	GDSC1	4.8128	6.7493	2.6334	1.5303
Sc-1	GDSC1	4.8171	6.3138	2.8129	0.7387
WSU-DLCL2	GDSC1; GDSC2	4.8213	8.5175	1.8421	5.1148
SU-DHL-16	GDSC1	4.8502	9.3361	1.4733	8.0374
RL	GDSC1	4.8781	9.5143	1.407	8.368
ME1	GDSC1; GDSC2	4.912	8.2311	2.0319	4.004
SU-DHL-4	GDSC1	5.042	6.3554	2.891	0.3361
TUR	GDSC1; GDSC2	5.0593	7.3248	2.5158	1.5538
KMS-18	CTRP2	5.3105	6.8629	4.3463	2.6345
Karpas-620	GDSC1; GDSC2	5.344	7.0052	2.7722	0.4466
GA-10	CTRP2	5.4572	7.3295	4.8648	6.2214
KMS-26	CTRP2	5.7383	6.7511	5.4121	3.3143
PL-21	GDSC1	5.9042	8.0664	2.6048	0.7073
MC116	CTRP2	5.9507	14.6713	0.9638	15.9327
MV4-11	CTRP2	5.9682	10.5045	3.7505	9.7802
NCI-H929	CTRP2	6.0197	8.3206	4.8856	4.9186
Ri-1	CTRP2	6.0328	10.2867	3.1944	6.4902
AMO1	CTRP2	6.2172	14.8837	1.0647	15.0453
EoL-1	CTRP2	6.2202	9.7829	4.3196	6.9168
REC-1	CTRP2	6.2471	9.8035	3.5771	4.4942
SU-DHL-10	CTRP2	6.2799	8.2352	4.3229	1.4149
RCH-ACV	CTRP2	6.3446	9.2671	3.8932	3.0317
SUP-T1	CTRP2	6.3713	9.3671	4.647	5.2723
MOLM-16	CTRP2	6.373	9.0345	4.0177	2.4911
SU-DHL-6	CTRP2	6.3805	10.2894	3.4344	4.9061
NU-DUL-1	CTRP2	6.4153	10.3872	3.411	4.9544
SK-MM-2	CTRP2	6.4331	10.2948	4.2337	6.8912
ST486	CTRP2	6.4992	9.2569	4.7997	4.417
NCO2	CTRP2	6.5284	8.412	5.2357	2.5711
SU-DHL-8	CTRP2	6.5323	12.3992	2.5211	8.5733
MOLT-13	CTRP2	6.5388	8.8135	5.0471	3.3285
SU-DHL-1	CTRP2	6.5495	7.7658	5.5594	1.2448
MHH-CALL-4	CTRP2	6.5614	11.3714	3.0384	6.3234
MOLM-6	CTRP2	6.5625	8.7079	4.2696	1.3356
ALL-SIL	CTRP2	6.5963	8.5704	5.2066	2.5883
MOLT-16	CTRP2	6.597	8.535	4.3602	0.9993
NU-DHL-1	CTRP2	6.5995	14.7267	2.1567	14.9371
HuNS1	CTRP2	6.5996	8.5335	5.2267	2.5019
SU-DHL-4	CTRP2	6.64	13.1952	2.2101	9.7048
WSU-DLCL2	CTRP2	6.6444	8.7835	5.1369	2.8004
SIG-M5	CTRP2	6.6747	8.2491	5.4127	1.6566
BCP-1	CTRP2	6.6753	9.5544	4.7834	4.1998
Karpas-620	CTRP2	6.7064	8.9894	5.0804	2.9383
697	CTRP2	6.7144	8.3194	5.405	1.6359
Peer	CTRP2	6.7416	8.2825	5.4392	1.4711
Pfeiffer	CTRP2	6.7441	9.1962	5.0066	3.1824
KYO-1	CTRP2	6.7513	8.6388	4.392	0.7877
KMS-12-BM	CTRP2	6.7621	10.5641	3.5508	3.8922
NB4	CTRP2	6.7633	9.0425	5.0939	2.8021
Mino	CTRP2	6.7701	9.4217	4.9156	3.5136
PF-382	CTRP2	6.7719	9.2505	4.9997	3.1698
MOLP-8	CTRP2	6.8047	8.5072	5.3742	1.6432
KMS-34	CTRP2	6.82	9.3527	4.1281	1.5974
Mono-Mac-1	CTRP2	6.8231	10.0939	3.8027	2.8099
MOLM-13	CTRP2	6.8601	8.5255	5.3998	1.4811
HPB-ALL	CTRP2	6.8688	8.9887	4.3055	0.9679
KMS-11	CTRP2	6.9198	11.8663	3.8269	7.7486
MM1.S	CTRP2	6.9353	10.4896	4.5134	4.9052
OPM-2	CTRP2	6.9598	9.2381	5.1308	2.391
RS4;11	CTRP2	6.9614	13.3943	3.1029	10.6192
SEM	CTRP2	6.9624	8.5325	5.4564	1.1633
SKM-1	CTRP2	7.0288	8.2786	5.6018	0.6183
A4/Fukuda	CTRP2	7.0319	9.4504	5.0772	2.5078
JVM-3	CTRP2	7.0521	8.6218	5.467	1.0392
Granta-519	CTRP2	7.1065	9.3505	5.1703	2.0593
OCI-AML-2	CTRP2	7.1231	8.88	5.3926	1.229
M-07e	CTRP2	7.1492	8.8997	5.3984	1.1838
MOLT-3	CTRP2	7.2009	8.4575	5.6113	0.4736
HDLM-2	CTRP2	7.2172	10.483	4.7099	3.7081
EJM	CTRP2	7.2357	9.216	5.3069	1.4193
TALL-1 [Human adult T-ALL]	CTRP2	7.2419	13.7301	2.3682	8.1063
Karpas-299	CTRP2	7.2571	12.0575	3.9787	6.5943
Toledo	CTRP2	7.2613	12.9995	3.5215	8.4397
RPMI-8226	CTRP2	7.2757	9.7749	5.078	2.2107
U266B1	CTRP2	7.2831	10.1416	4.9131	2.8286
Ci-1	CTRP2	7.313	8.0653	5.8029	0.0554
CA46	CTRP2	7.3166	12.6426	3.736	7.4862
Hs 611.T	CTRP2	7.3372	12.0629	4.0326	6.2555
OCI-M1	CTRP2	7.3423	9.7321	5.1369	1.9191
L-428	CTRP2	7.3647	10.288	4.896	2.7948
U-937	CTRP2	7.3713	10.0128	5.0267	2.2937
Raji	CTRP2	7.3827	9.1688	5.4062	0.9545
EB1	CTRP2	7.384	9.3013	5.3503	1.1342
BV-173	CTRP2	7.4508	12.3599	3.968	6.3483
OCI-AML-5	CTRP2	7.4543	17.5249	1.4326	15.9909
SUP-HD1	CTRP2	7.4852	9.8043	5.186	1.5992
OCI-Ly3	CTRP2	7.4922	9.0518	5.5076	0.5783
SUP-M2	CTRP2	7.5034	8.778	5.6193	0.3005
SUP-B15	CTRP2	7.5043	9.054	5.5123	0.5585
L-540	CTRP2	7.5087	9.1066	4.5281	0.1723
OCI-AML-3	CTRP2	7.5217	8.94	5.565	0.4154
DND-41	CTRP2	7.5506	13.2124	3.6248	7.5768
Kasumi-1	CTRP2	7.5733	11.2185	4.5935	3.7015
KMS-21-BM	CTRP2	7.5876	9.4152	5.4052	0.8053
A3/Kawakami	CTRP2	7.6161	8.4549	5.7767	0.0411
LP-1	CTRP2	7.6187	11.5348	4.4741	4.1073
Kasumi-2	CTRP2	7.6488	12.6849	3.9473	6.1458
Ki-JK	CTRP2	7.6616	9.9136	5.2333	1.2814
HD-MY-Z	CTRP2	7.665	9.0784	5.5731	0.3319
AML-193	CTRP2	7.6694	8.7821	5.6833	0.1336
Reh	CTRP2	7.6798	13.9834	3.3415	8.5089
KMS-20	CTRP2	7.6802	12.409	4.1004	5.4947
EHEB	CTRP2	7.6807	10.4966	4.9888	2.1005
ME1	CTRP2	7.6959	10.5374	4.9792	2.119
DEL	CTRP2	7.6993	8.9253	5.6435	0.1867
BL-70	CTRP2	7.715	8.7095	5.7251	0.0743
KMS-27	CTRP2	7.7676	8.9188	5.6715	0.1278
NOMO-1	CTRP2	7.7676	10.1059	5.2063	1.281
Karpas-422	CTRP2	7.7819	9.1409	5.5973	0.2411
Jurkat	CTRP2	7.7956	9.0189	5.6466	0.1564
TF-1	CTRP2	7.8094	9.6429	5.4171	0.633
JeKo-1	CTRP2	7.8188	10.2921	5.1534	1.4093
HL-60	CTRP2	7.8274	9.1231	5.6215	0.1866
MOTN-1	CTRP2	7.8741	9.9745	5.3138	0.8761
EM-2	CTRP2	7.8787	9.342	5.5619	0.2738
P31/FUJ	CTRP2	7.9027	9.2891	5.5906	0.2155
KE-37	CTRP2	7.9158	9.1288	5.6525	0.1219
CMK	CTRP2	7.9299	9.1258	5.6587	0.1118
KO52	CTRP2	7.9408	9.2594	5.6158	0.1661
JJN-3	CTRP2	7.962	19.0537	1.0605	16.3705
SET-2	CTRP2	7.9978	9.2535	5.639	0.1228
RPMI-8402	CTRP2	8.0161	9.4762	5.5669	0.2222
DB	CTRP2	8.0191	9.8798	5.4173	0.5229
Namalwa	CTRP2	8.022	10.0321	5.3591	0.664
KE-97	CTRP2	8.0266	9.3964	5.5994	0.1693
P12-Ichikawa	CTRP2	8.0291	9.2338	5.6571	0.0966
RL	CTRP2	8.0292	9.2947	5.6361	0.1204
SR	CTRP2	8.031	9.8847	5.4205	0.5096
PL21	CTRP2	8.0347	9.247	5.6545	0.0984
MJ	CTRP2	8.0743	12.3851	4.3636	3.972
Daudi	CTRP2	8.0749	9.6086	5.5418	0.2469
HEL 92.1.7	CTRP2	8.0799	9.2093	5.6833	0.0646
RPMI-6666	CTRP2	8.0809	9.5126	5.5786	0.1866
GDM-1	CTRP2	8.1211	10.847	5.0733	1.4204
LAMA-84	CTRP2	8.1388	9.7211	5.5258	0.2549
K-562	CTRP2	8.1581	14.4946	3.4245	7.488
HEL	CTRP2	8.1644	9.5335	5.6022	0.136
L-363	CTRP2	8.1755	18.9537	1.2682	15.3406
MHH-CALL-3	CTRP2	8.1846	16.381	2.5329	10.8566
HT	CTRP2	8.2478	9.3378	5.6976	0.0387
Ku812	CTRP2	8.2773	10.0626	5.4556	0.336
OCI-Ly19	CTRP2	8.2873	10.015	5.477	0.2939
KMM-1	CTRP2	8.3202	11.3055	4.981	1.5539
CML-T1	CTRP2	8.3292	9.6969	5.6051	0.1043
P3HR-1	CTRP2	8.3789	16.5845	1.7602	8.8937
THP-1	CTRP2	8.409	9.9798	5.5359	0.1712
JURL-MK1	CTRP2	8.4259	9.8903	5.5731	0.1229
KHM-1B	CTRP2	8.4501	9.8841	5.5839	0.1076
NALM-6	CTRP2	8.4784	10.0142	5.5492	0.141
OCI-Ly10	CTRP2	8.5113	10.7798	5.2825	0.6034
KCL-22	CTRP2	8.5432	10.1663	5.5199	0.1644
F-36P	CTRP2	8.6172	15.5168	3.2425	7.5616
HuT 78	CTRP2	8.7244	20.1563	1.0781	15.0982
KM-H2	CTRP2	8.7632	10.1706	5.5958	0.0608
MOLP-2	CTRP2	11.3151	24.0193	0.9779	11.8754

Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	8.4033	10.3304	5.4072	0.3839
TE8	CTRP2	9.2902	25.2196	-0.991	20.122
KYSE-140	GDSC1; GDSC2	1.337	4.0866	0.9076	19.6443
KYSE-510	GDSC1	1.8764	3.7149	1.6219	16.2513
KYSE-180	GDSC1; GDSC2	2.6298	4.7957	1.951	9.6468
KYSE-270	GDSC1; GDSC2	2.7836	4.5299	2.2264	7.662
TE-8	GDSC1; GDSC2	3.028	4.9161	2.2683	6.69
OE33	GDSC1; GDSC2	3.0993	5.3822	2.1009	7.419
TE-5	GDSC1; GDSC2	3.1971	4.9224	2.4154	5.3971
EC-GI-10	GDSC1; GDSC2	3.23	5.2184	2.2961	5.9748
TE-9	GDSC1; GDSC2	3.439	5.1134	2.5218	4.1813
TE-11	GDSC1	3.5188	5.9819	2.1522	7.0122
OE21	GDSC1; GDSC2	3.524	5.9776	2.1585	6.0029
KYSE-520	GDSC1; GDSC2	3.562	5.3789	2.486	4.0915
COLO 680N	GDSC1; GDSC2	3.6126	5.9463	2.2434	5.3225
TE-4	GDSC1; GDSC2	3.6141	5.818	2.3082	4.9598
KYSE-70	GDSC1; GDSC2	3.6194	5.2394	2.5984	3.3419
TE-6	GDSC1; GDSC2	3.6489	5.2244	2.6275	3.1187
TE-15	GDSC1; GDSC2	3.6506	6.5084	1.9936	6.6216
KYSE-450	GDSC1; GDSC2	3.7499	5.7097	2.4632	3.8071
T.T	GDSC1; GDSC2	3.7924	6.5571	2.0777	5.8359
TE-10	GDSC1	4.2178	6.5426	2.383	3.8774
KYSE-410	GDSC1; GDSC2	4.2544	6.5359	2.4097	3.1435
TE-1	GDSC1; GDSC2	4.4278	7.9455	1.8542	5.7565
KYSE-150	GDSC1; GDSC2	5.1307	9.8991	1.391	6.892
OE19	GDSC1; GDSC2	6.6554	13.6924	0.5812	8.2877
KYSE-410	CTRP2	7.5985	10.0457	5.1423	1.6423
TE-5	CTRP2	7.7057	9.4097	5.4626	0.5735
TE-9	CTRP2	7.7177	9.0902	5.5903	0.2763
KYSE-70	CTRP2	7.9658	9.8484	5.4062	0.576
KYSE-150	CTRP2	8.1021	9.2825	5.6662	0.0769
COLO 680N	CTRP2	8.1256	10.0184	5.4097	0.4908
TE-11	CTRP2	8.2038	10.2106	5.3694	0.5467
KYSE-180	CTRP2	8.2577	11.381	4.9167	1.811
KYSE-510	CTRP2	8.2744	9.9566	5.4932	0.2698
OE33	CTRP2	8.2793	10.1263	5.4328	0.3792
KYSE-450	CTRP2	8.3177	9.6925	5.6025	0.1087
EC-GI-10	CTRP2	8.3235	10.2524	5.4038	0.4205
KYSE-30	CTRP2	8.3459	9.4884	5.6809	0.0412
OE19	CTRP2	8.3493	9.3673	5.7216	0.0213
OE21	CTRP2	8.3982	9.9992	5.5251	0.1882
KYSE-520	CTRP2	8.4694	10.3798	5.4154	0.3456
TE-10	CTRP2	8.524	10.2821	5.4719	0.2352
TE-1	CTRP2	8.7294	10.3662	5.518	0.1332
KYSE-140	CTRP2	8.9585	10.8883	5.4198	0.2083
TE-4	CTRP2	10.8466	28.7271	-1.5869	19.3548
TE-6	CTRP2	12.141	38.8461	-5.5948	25.2024
TE-14	CTRP2	13.3353	29.4972	-0.3062	13.1594

Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	8.2051	9.8569	5.5024	0.2751
PSN1	GDSC1; GDSC2	1.0032	3.5401	0.7286	21.8278
MIA PaCa-2	GDSC1; GDSC2	2.1944	6.1428	0.8888	16.7456
HuP-T4	GDSC1; GDSC2	2.5473	5.0049	1.7717	10.8821
SUIT-2	GDSC1; GDSC2	2.7337	6.0074	1.4622	12.0012
Panc 10.05	GDSC1; GDSC2	3.1318	5.991	1.8259	8.8616
BxPC-3	GDSC1; GDSC2	3.156	5.3004	2.1912	6.7595
HPAC	GDSC1; GDSC2	3.3008	5.0537	2.4384	4.9936
SU.86.86	GDSC1; GDSC2	3.3445	4.4369	2.7831	2.9548
KP-4	GDSC1; GDSC2	3.4139	5.2451	2.4359	4.7218
KP-3	GDSC1; GDSC2	3.459	5.1882	2.5004	4.2526
AsPC-1	GDSC1; GDSC2	3.5118	5.8522	2.2113	5.7376
SW1990	GDSC1; GDSC2	3.577	7.6934	1.3449	10.3788
KP-1N	GDSC1; GDSC2	3.5913	6.393	2.0047	6.6986
Capan-1	GDSC1; GDSC2	3.6248	7.5673	1.446	9.7095
MZ-PC-1	GDSC1; GDSC2	3.651	5.6965	2.3965	4.6119
Panc 03.27	GDSC1; GDSC2	3.7486	6.6502	1.9986	6.37
Panc 02.03	GDSC1; GDSC2	3.8251	5.8246	2.4611	3.6637
DAN-G	GDSC1; GDSC2	3.864	5.7746	2.5127	3.3071
HuP-T3	GDSC1; GDSC2	3.9562	6.1001	2.4193	3.6309
Panc 08.13	GDSC1; GDSC2	3.9601	6.148	2.3989	3.7333
Hs 766T	GDSC1; GDSC2	4.0428	6.5763	2.2493	4.3787
PL4	GDSC1; GDSC2	4.0847	6.9801	2.083	5.1945
CFPAC-1	GDSC1; GDSC2	4.1522	8.0035	1.6319	7.5022
KP-2	GDSC1; GDSC2	4.209	5.4043	2.8941	0.8617
PaTu 8902	GDSC1; GDSC2	4.3115	8.6379	1.4367	8.2194
PaTu 8988t	GDSC1; GDSC2	4.618	6.1437	2.7889	0.8849
Capan-2	GDSC1; GDSC2	4.6762	6.8013	2.5391	1.8885
Panc 04.03	GDSC1; GDSC2	4.8508	7.1639	2.4757	1.9615
YAPC	GDSC1; GDSC2	5.0318	6.5774	2.8041	0.5254
QGP-1	GDSC1	5.2586	6.8505	2.7951	0.4967
HPAF-II	GDSC1; GDSC2	6.1279	8.6575	2.4747	0.8546
SNU-410	CTRP2	6.5492	13.8487	1.8247	11.4473
KP-4	CTRP2	7.1183	8.7211	5.4596	1.0037
SNU-213	CTRP2	7.3309	13.0194	3.5623	8.1653
Panc 08.13	CTRP2	7.4041	9.4597	5.2925	1.3093
CFPAC-1	CTRP2	7.4067	11.878	4.17	5.6007
PaTu 8988t	CTRP2	7.4748	8.7355	5.6234	0.3037
PK-45H	CTRP2	7.6002	10.6233	4.8848	2.5642
QGP-1	CTRP2	7.6379	9.1684	5.5271	0.4487
PSN1	CTRP2	7.7577	10.1801	5.1694	1.4085
YAPC	CTRP2	7.8132	9.1332	5.6124	0.2053
PaTu 8988s	CTRP2	7.8753	9.643	5.4465	0.5239
DAN-G	CTRP2	7.9041	9.5815	5.4826	0.4266
SUIT-2	CTRP2	7.9278	9.8796	5.3769	0.6706
MIA PaCa-2	CTRP2	7.9286	9.2211	5.6248	0.1561
TCC-Pan2	CTRP2	7.9439	9.5516	5.5104	0.3506
HPAF-II	CTRP2	8.0004	10.122	5.3135	0.7969
Hs 766T	CTRP2	8.015	9.6553	5.5008	0.3429
PaTu 8902	CTRP2	8.0332	9.106	5.7018	0.0549
Capan-2	CTRP2	8.0493	9.8223	5.4521	0.4304
L3.3	CTRP2	8.0697	9.3346	5.6369	0.1121
HuP-T4	CTRP2	8.1133	9.6194	5.5527	0.218
KP-2	CTRP2	8.1191	9.2576	5.6805	0.0624
AsPC-1	CTRP2	8.2373	10.1422	5.4096	0.443
Capan-1	CTRP2	8.2804	9.8749	5.5249	0.217
Panc 04.03	CTRP2	8.4009	10.1176	5.4839	0.249
Panc 05.04	CTRP2	8.4251	10.0433	5.5195	0.1899
HPAC	CTRP2	8.4393	9.945	5.5591	0.1365
Panc 03.27	CTRP2	8.6794	10.2588	5.537	0.121
HuP-T3	CTRP2	8.7138	15.8354	3.1548	7.7645
SW1990	CTRP2	8.7221	10.4117	5.4997	0.1551
KP-3	CTRP2	8.7233	10.6228	5.4259	0.2541
Panc 02.03	CTRP2	8.7284	10.305	5.5385	0.1122
BxPC-3	CTRP2	8.9577	10.99	5.3836	0.2587
PK-59	CTRP2	9.1825	17.009	2.9047	8.0821
Panc 10.05	CTRP2	9.2262	11.2063	5.4066	0.1733
SU.86.86	CTRP2	10.5937	39.9028	-7.2591	29.2774

Cancer Drug Sensitivity Data Curated from 108 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	11.0636	24.7786	0.4574	13.7322
G-mel	GDSC1	0.5179	4.8382	-0.2536	32.5598
RPMI-7951	GDSC1; GDSC2	1.6595	4.6428	1.0316	17.819
A-375	GDSC1; GDSC2	1.8671	3.9049	1.5441	14.4439
SK-MEL-30	GDSC1	1.9031	7.2846	0.062	24.9328
A101D	GDSC1; GDSC2	1.9916	5.9678	0.7748	18.001
A2058	GDSC1; GDSC2	2.1446	4.4618	1.6133	13.077
LOX-IMVI	GDSC1; GDSC2	2.2632	5.1219	1.4374	13.6046
MZ-MEL-2	GDSC1	2.2786	7.504	0.3084	22.247
WM1552C	GDSC1; GDSC2	2.4209	4.6729	1.8013	11.136
SK-MEL-5	GDSC1	2.4669	5.5806	1.4196	15.1037
WT2-iPS	GDSC1; GDSC2	2.5402	5.1153	1.7124	11.2265
COLO 792	GDSC1; GDSC2	2.5447	5.4386	1.5622	12.028
WM793	GDSC1; GDSC2	2.6536	6.4495	1.1713	13.8223
Mel Ho	GDSC1	2.693	5.243	1.7975	11.9191
Hs 940.T	GDSC1	2.7187	8.5794	0.175	21.3825
COLO 829	GDSC1; GDSC2	2.8256	4.9574	2.061	8.4352
451Lu	GDSC1	2.9731	6.4433	1.4618	13.0906
CHL-1	GDSC1; GDSC2	3.0089	5.9887	1.7195	9.791
WM35	GDSC1; GDSC2	3.0756	6.0111	1.7669	9.3428
COLO 679	GDSC1; GDSC2	3.0758	4.9587	2.2904	6.4308
COLO 800	GDSC1	3.1653	4.5511	2.5723	5.3444
IST-MEL1	GDSC1; GDSC2	3.231	5.5723	2.1201	6.9552
UACC-62	GDSC1; GDSC2	3.2629	5.4553	2.2056	6.393
HT-144	GDSC1; GDSC2	3.2895	6.276	1.8178	8.4883
IPC-298	GDSC1	3.3082	4.0507	2.9461	2.4766
WM278	GDSC1; GDSC2	3.3365	5.3322	2.3289	5.5139
G-361	GDSC1; GDSC2	3.419	5.2222	2.4514	4.6225
MeWo	GDSC1; GDSC2	3.4678	5.0982	2.5523	3.9423
SK-MEL-28	GDSC1	3.5394	6.5806	1.8701	8.7692
IGR-37	GDSC1; GDSC2	3.5652	6.0331	2.1634	5.8779
SK-MEL-2	GDSC1; GDSC2	3.6544	6.1483	2.1754	5.6044
A-388	GDSC1	3.6711	5.9678	2.2775	5.7964
HMV-II	GDSC1; GDSC2	3.6743	5.8462	2.3401	4.6474
SK-MEL-24	GDSC1; GDSC2	3.6778	7.6767	1.4336	9.6502
UACC-257	GDSC1; GDSC2	3.7863	5.7257	2.4816	3.631
M14	GDSC1; GDSC2	3.8157	6.2437	2.2493	4.8408
SK-MEL-1	GDSC1; GDSC2	3.8188	6.0635	2.34	4.3376
SK-MEL-31	GDSC1	3.9667	6.6955	2.1376	5.9518
A-431	GDSC1	4.043	7.0127	2.0375	6.401
RVH-421	GDSC1	4.0889	8.9133	1.1368	11.8468
Hs 938.T	GDSC1	4.1184	12.655	-0.6985	21.2091
WM115	GDSC1; GDSC2	4.1791	10.5551	0.3925	13.9144
VMRC-MELG	GDSC1	4.3085	6.0661	2.6587	2.1004
COLO 783	GDSC1	4.4152	9.6661	1.0084	11.7723
SH-4	GDSC1; GDSC2	4.5055	8.1215	1.8225	5.7789
LB2518-MEL	GDSC1	4.594	5.7557	2.9321	0.4689
CP50-MEL-B	GDSC1	4.7839	8.2533	1.9421	5.3988
Mel JuSo	GDSC1; GDSC2	4.7873	11.0195	0.6155	11.4777
IGR-1	GDSC1; GDSC2	4.7888	7.605	2.2441	3.1386
GAK	GDSC1; GDSC2	4.8033	6.4499	2.7523	0.8615
DJM-1	GDSC1	5.097	11.6686	0.5193	12.862
SK-MEL-3	GDSC1	5.0981	7.4407	2.4866	1.8955
MMAc-SF	GDSC1	5.2421	6.8751	2.7792	0.5556
MZ-MEL-7	GDSC1	5.3742	7.3198	2.6656	0.8544
LB373-MEL-D	GDSC1	5.5451	15.3739	-0.9667	18.767
CP66-MEL	GDSC1	5.7744	12.9766	0.3538	12.2361
LOX-IMVI	CTRP2	6.2271	8.6901	4.8705	4.5927
SK-MEL-28	CTRP2	6.7367	7.992	5.5691	0.9917
SK-MEL-2	CTRP2	6.982	8.7629	5.3642	1.4767
Hs 839.T	CTRP2	7.1129	8.0266	5.7405	0.2044
Hs 944.T	CTRP2	7.1245	9.2346	4.3252	0.7439
WM1799	CTRP2	7.1893	9.4168	5.1898	1.8918
G-361	CTRP2	7.2593	9.1992	5.3274	1.3246
SK-MEL-1	CTRP2	7.3081	8.5906	5.6073	0.4224
K029AX	CTRP2	7.3438	9.123	5.4056	0.9877
HMCB	CTRP2	7.3841	8.7455	5.5803	0.4496
CJM [Human melanoma]	CTRP2	7.3943	9.417	5.3058	1.2733
COLO 741	CTRP2	7.4237	10.8221	4.684	3.5395
WM266-4	CTRP2	7.4386	8.9001	5.5437	0.5139
Mel Ho	CTRP2	7.4438	9.7804	5.1734	1.6834
A-375	CTRP2	7.4564	11.9644	4.1624	5.56
WM115	CTRP2	7.6151	9.033	5.5694	0.3614
COLO 792	CTRP2	7.6199	10.5789	4.9166	2.4254
IGR-37	CTRP2	7.6313	9.0527	5.5688	0.3556
Mel JuSo	CTRP2	7.6836	9.2478	5.5162	0.4521
WM793	CTRP2	7.7108	10.0457	5.2025	1.3403
UACC-62	CTRP2	7.7205	8.7289	5.7204	0.0783
SK-MEL-24	CTRP2	7.7226	10.2549	5.1185	1.609
IPC-298	CTRP2	7.7274	8.9208	5.6558	0.1596
SK-MEL-5	CTRP2	7.7313	9.0289	5.6183	0.2199
WT2-iPS	CTRP2	7.7645	9.0133	5.6368	0.1793
UACC-257	CTRP2	7.788	10.9647	4.8405	2.5227
RPMI-7951	CTRP2	7.8076	9.2581	5.5644	0.2942
Hs 294T	CTRP2	7.8224	9.0647	5.6404	0.1589
SK-MEL-31	CTRP2	7.8316	9.0975	5.6322	0.1688
SK-MEL-30	CTRP2	7.8443	9.0667	5.6479	0.143
IGR-1	CTRP2	7.8976	9.5556	5.4896	0.4138
Hs 934.T	CTRP2	7.9404	9.039	5.6922	0.0743
COLO 829	CTRP2	7.9467	10.9519	4.9359	2.025
Hs 852.T	CTRP2	7.9628	9.9581	5.3616	0.6907
SK-MEL-3	CTRP2	7.9663	9.6158	5.4955	0.3724
IGR-39	CTRP2	7.9666	9.1224	5.673	0.0896
Hs 936.T	CTRP2	8.003	9.3149	5.6194	0.1469
A101D	CTRP2	8.0128	9.0941	5.6988	0.0595
MDA-MB-435S	CTRP2	8.0426	9.4706	5.579	0.1956
RVH-421	CTRP2	8.1056	9.3663	5.6388	0.1038
WM88	CTRP2	8.1311	12.0674	4.5429	3.2401
A2058	CTRP2	8.134	9.3967	5.6385	0.0996
MeWo	CTRP2	8.1902	9.9686	5.4553	0.3676
Hs 895.T	CTRP2	8.2005	9.4233	5.6529	0.0762
HT-144	CTRP2	8.2105	9.9791	5.4596	0.3519
Hs 688(A).T	CTRP2	8.2443	18.1455	1.7149	13.7151
COLO 800	CTRP2	8.2838	9.9452	5.501	0.2541
Hs 940.T	CTRP2	8.3419	10.1263	5.4578	0.3106
WM983B	CTRP2	8.4249	10.6145	5.309	0.5827
Malme-3M	CTRP2	8.5158	11.2033	5.1181	1.0146
EquiPSC Line K2	GDSC1	7.0812	22.295	-3.2435	23.1086

Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KYSE-220	GDSC1; GDSC2	1.3604	4.282	0.8595	19.7951
HCE-4	GDSC1	2.7516	6.1193	1.4236	14.0704
FLO-1	GDSC1; GDSC2	3.2271	6.4669	1.6698	9.4752
OACP4 C	GDSC1; GDSC2	3.2907	7.5305	1.1915	11.9391
ESO-26	GDSC1; GDSC2	3.3961	6.1229	1.9827	7.2966
TE-12	GDSC1	3.7145	7.9198	1.3414	11.613
KYAE-1	GDSC1; GDSC2	3.8488	5.5124	2.6286	2.7137
SK-GT-4	GDSC1; GDSC2	4.2652	8.007	1.7113	6.8398
OACM5.1 C	GDSC1; GDSC2	4.7345	9.5353	1.2991	8.097
KYSE-50	GDSC1; GDSC2	5.2329	6.9042	2.7645	0.5254
ESO-51	GDSC1; GDSC2	5.2456	7.7876	2.4152	1.7796

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1; GDSC2	3.9195	6.8021	2.0512	5.7071
COLO 684	CTRP2	7.8437	12.4568	4.1851	4.9436

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CHP-134	GDSC2	0.4984	2.8779	0.2215	21.1696
SK-N-MC-IXC	GDSC1	0.8844	2.1549	0.8676	25.1208
NB69	GDSC1; GDSC2	1.9142	4.3166	1.4336	14.8319
SiMa	GDSC1; GDSC2	1.9987	4.2742	1.54	13.9781
GOTO	GDSC1; GDSC2	2.1132	5.8623	0.9434	16.7213
IMR-5	GDSC1; GDSC2	2.1987	3.8756	1.9104	11.3485
MHH-NB-11	GDSC1	2.2728	4.0281	1.9289	15.4911
SJNB-5	GDSC1	2.3035	7.2607	0.4506	21.3942
NH-12	GDSC1; GDSC2	2.3392	5.2339	1.4603	13.2332
SJNB-10	GDSC1; GDSC2	2.4675	5.8234	1.3033	13.6723
CHP-126	GDSC1	2.5192	5.1629	1.6694	13.3552
KP-N-YN	GDSC1; GDSC2	2.8108	7.1142	0.9847	14.3685
SJNB-14	GDSC1; GDSC2	2.8487	5.2452	1.9421	9.0199
Kelly	GDSC1; GDSC2	2.8699	7.5547	0.818	15.0851
SK-N-SH	GDSC1; GDSC2	2.9215	7.4147	0.9329	14.331
SJNB-13	GDSC1; GDSC2	3.0093	7.3018	1.0658	13.3745
NB1	GDSC1; GDSC2	3.0653	4.9276	2.2963	6.4274
CHP-212	GDSC1; GDSC2	3.1624	8.3578	0.6698	15.0513
GI-ME-N	GDSC1; GDSC2	3.5597	8.058	1.149	11.4846
SK-N-AS	GDSC1; GDSC2	3.5863	6.6988	1.8484	7.5793
SJNB-7	GDSC1; GDSC2	3.5992	6.2063	2.1038	6.1296
TGW	GDSC1; GDSC2	3.752	6.7282	1.9626	6.5619
SK-N-BE(2)-M17	GDSC1; GDSC2	3.8321	7.1429	1.8182	7.1782
SJNB-6	GDSC1	4.0919	5.9609	2.5756	2.9673
NB(TU)1	GDSC1; GDSC2	4.1566	7.094	2.0781	5.0791
LA-N-6	GDSC1	4.3999	6.762	2.3957	3.4501
SJNB-12	GDSC1; GDSC2	4.4853	7.6283	2.044	4.6489
SJNB-17	GDSC1	4.6364	10.0386	0.986	11.3638
SK-N-FI	GDSC1; GDSC2	4.8844	9.8787	1.2366	8.1335
SK-N-DZ	GDSC1; GDSC2	5.2635	18.7113	-2.8206	23.7535
KP-N-YS	GDSC1	5.8386	8.056	2.5816	1.0008
SK-N-DZ	CTRP2	6.4418	10.1617	4.3068	6.5707
IMR-32	CTRP2	6.6226	11.2298	3.9164	7.8808
SK-N-SH	CTRP2	7.2982	10.5289	4.7411	3.4779
Kelly	CTRP2	7.3715	11.4736	4.3403	4.9683
CHP-126	CTRP2	7.3769	9.1676	4.4565	0.3233
NB1	CTRP2	7.4173	11.2575	4.4741	4.3724
KP-N-YN	CTRP2	7.6299	10.8449	4.8015	2.841
SK-N-FI	CTRP2	7.6584	9.3027	5.4836	0.5457
SK-N-BE(2)	CTRP2	7.7192	13.7926	3.4617	7.9741
NH-6	CTRP2	7.8456	9.5052	5.4868	0.4434
KP-N-SI9s	CTRP2	8.0728	18.2114	1.5574	14.5316
CHP-212	CTRP2	8.1601	9.7803	5.5127	0.2711
SK-N-AS	CTRP2	8.3797	9.8852	5.5582	0.1487

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuCC-T1	GDSC1; GDSC2	4.8255	10.569	0.8621	10.1641
HuH-28	CTRP2	7.0903	8.9531	5.3415	1.4435
SNU-869	CTRP2	7.6117	9.3479	5.4441	0.6786
SNU-478	CTRP2	7.6814	9.4531	5.4342	0.6627
SNU-1196	CTRP2	8.2702	9.7942	5.5497	0.183
HuCC-T1	CTRP2	8.281	9.828	5.5418	0.1918
SNU-1079	CTRP2	8.4573	10.2541	5.4565	0.2778

Cancer Drug Sensitivity Data Curated from 124 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CAL-148	GDSC2	1.7305	3.5102	1.3024	10.3586
HCC1599	GDSC1; GDSC2	2.0005	3.9991	1.0008	6.3026
MDA-MB-468	GDSC1; GDSC2	2.3963	5.8758	1.2103	14.3523
HCC1806	GDSC1; GDSC2	2.4829	6.0913	1.1882	14.2028
CAL-51	GDSC1; GDSC2	2.5603	4.9934	1.7898	10.7091
MDA-MB-436	GDSC1; GDSC2	2.6326	4.2131	2.2231	8.151
HCC70	GDSC1; GDSC2	2.6985	4.7829	2.0238	9.005
HCC1187	GDSC1; GDSC2	3.0941	3.9451	2.8048	3.5229
BT-20	GDSC1; GDSC2	3.3344	4.375	2.8057	2.8448
Evsa-T	GDSC1; GDSC2	3.3557	5.2018	2.41	4.9958
BT-549	GDSC1; GDSC2	3.3784	9.1729	0.4434	15.5878
UACC-812	GDSC2	3.4319	6.5275	1.2671	5.8138
MDA-MB-361	GDSC1; GDSC2	3.4381	5.0663	2.5445	4.0439
MCF-7	GDSC1; GDSC2	3.4888	5.5754	2.3311	5.1091
DU4475	GDSC1; GDSC2	3.5036	6.2879	1.9875	6.9831
UACC-893	GDSC1; GDSC2	3.5138	5.7615	2.2582	5.4548
MDA-MB-175-VII	GDSC1; GDSC2	3.562	6.8257	1.7659	8.071
HCC2157	GDSC1; GDSC2	3.6768	5.6602	2.4337	4.1125
AU565	GDSC1; GDSC2	3.7267	6.9175	1.8494	7.2229
HCC1143	GDSC1; GDSC2	3.7429	5.8121	2.4079	4.1123
JIMT-1	GDSC1; GDSC2	3.8013	7.8368	1.4505	9.2386
HCC1395	GDSC1; GDSC2	3.8115	7.6092	1.5714	8.5557
MDA-MB-231	GDSC1; GDSC2	3.8208	6.6893	2.0338	5.9972
MDA-MB-415	GDSC1; GDSC2	3.8344	5.5988	2.5771	3.0081
HCC1419	GDSC1; GDSC2	3.941	8.2645	1.3457	9.4869
HDQ-P1	GDSC1; GDSC2	3.9465	6.2041	2.3623	3.945
CAL-85-1	GDSC1; GDSC2	3.9853	5.9647	2.5041	3.1131
EFM-192A	GDSC1; GDSC2	4.0368	5.6025	2.7081	1.9661
ZR-75-30	GDSC1; GDSC2	4.1662	5.8945	2.6526	2.0429
CAMA-1	GDSC1; GDSC2	4.2402	8.1245	1.6363	7.2729
HCC202	GDSC1; GDSC2	4.2789	8.6146	1.4246	8.327
HCC1954	GDSC1; GDSC2	4.3362	6.2887	2.5743	2.1755
MFM-223	GDSC1; GDSC2	4.347	6.6652	2.4078	2.9909
HCC38	GDSC1; GDSC2	4.4089	6.9839	2.2981	3.4497
CAL-120	GDSC1; GDSC2	4.4106	7.9604	1.8353	5.8718
Hs 578T	GDSC1; GDSC2	4.6376	10.5313	0.7463	11.1045
MRK-nu-1	GDSC1; GDSC2	4.8798	7.1276	2.507	1.7826
MDA-MB-157	GDSC1; GDSC2	4.9144	7.4037	2.4056	2.1945
EFM-19	GDSC1; GDSC2	4.9848	7.1485	2.5523	1.4747
HCC1937	GDSC1; GDSC2	4.9869	8.8191	1.806	5.0078
OCUB-M	GDSC1; GDSC2	5.0171	7.3247	2.4943	1.6839
HCC1428	GDSC1; GDSC2	5.0244	6.6548	2.7711	0.6296
MDA-MB-157	CTRP2	5.0498	9.0308	3.6585	12.124
BT-474	GDSC1; GDSC2	5.1754	6.5014	2.8898	0.2416
MDA-MB-453	GDSC1; GDSC2	5.3055	7.338	2.6281	0.905
T-47D	GDSC1; GDSC2	5.331	7.2117	2.6887	0.6905
HCC1569	GDSC1; GDSC2	5.3959	9.1833	1.8861	3.9907
BT-483	GDSC1; GDSC2	5.4588	7.6504	2.5737	0.9777
HCC2218	GDSC1; GDSC2	5.5384	7.2675	2.7532	0.4039
HCC1500	GDSC1; GDSC2	5.6331	7.0241	2.8749	0.1434
COLO 824	GDSC1; GDSC2	5.6356	8.1158	2.4691	1.2076
MDA-MB-330	GDSC1; GDSC2	6.6722	9.1397	2.5154	0.4898
KPL-1	CTRP2	6.9524	7.6924	5.7998	0.1465
MDA-MB-415	CTRP2	7.0674	9.0508	5.2839	1.6787
SK-BR-3	CTRP2	7.2747	11.5695	4.2278	5.5595
CAL-120	CTRP2	7.3817	8.8731	5.5282	0.5903
CAMA-1	CTRP2	7.3899	9.0253	5.4698	0.7531
Hs 578Bst	CTRP2	7.5146	9.8824	5.1678	1.6341
JIMT-1	CTRP2	7.5576	9.4649	5.3699	0.9324
HCC1806	CTRP2	7.559	18.1814	1.1873	16.6346
UACC-812	CTRP2	7.6654	9.5923	5.37	0.8545
ZR-75-1	CTRP2	7.6696	9.0722	5.5774	0.3209
HCC1428	CTRP2	7.6707	8.7304	5.7019	0.1084
HDQ-P1	CTRP2	7.6711	9.2349	5.5158	0.4593
DU4475	CTRP2	7.6816	13.2081	3.7181	7.0112
HCC38	CTRP2	7.7139	9.6028	5.389	0.7676
HCC1143	CTRP2	7.7883	11.1307	4.7657	2.7963
CAL-148	CTRP2	7.8235	9.1736	5.6017	0.2202
Hs 578T	CTRP2	7.9042	9.9316	5.3453	0.7689
HMC-1-8	CTRP2	7.9468	9.0298	5.6976	0.0685
HCC1419	CTRP2	7.9582	9.68	5.4679	0.4354
BT-474	CTRP2	7.9901	9.3456	5.6037	0.1718
HCC1500	CTRP2	8.0993	9.8807	5.4509	0.4122
HCC2218	CTRP2	8.113	9.748	5.5059	0.2984
HCC1937	CTRP2	8.1591	10.6277	5.1832	1.0608
AU565	CTRP2	8.1668	11.2796	4.9123	1.9041
MCF-7	CTRP2	8.2106	10.8176	5.13	1.1808
HCC1395	CTRP2	8.2353	10.9386	5.0921	1.2765
ZR-75-30	CTRP2	8.2663	10.0094	5.4708	0.3117
EFM-192A	CTRP2	8.3381	9.9344	5.5255	0.2017
MDA-MB-361	CTRP2	8.3678	11.3558	4.9839	1.5081
HCC202	CTRP2	8.3972	10.7591	5.2407	0.7606
CAL-51	CTRP2	8.4203	9.8935	5.57	0.1273
MDA-MB-468	CTRP2	8.4269	9.8648	5.5823	0.1129
MDA-MB-453	CTRP2	8.4802	10.0473	5.5384	0.1537
MDA-MB-231	CTRP2	8.488	10.5373	5.3646	0.4366
BT-20	CTRP2	8.5819	10.1159	5.5513	0.1212
CAL-85-1	CTRP2	8.7007	14.287	3.8702	5.0891
BT-549	CTRP2	8.7658	10.6627	5.4277	0.2408
HCC1954	CTRP2	8.9608	10.8382	5.4382	0.1844
T-47D	CTRP2	9.0028	11.075	5.3704	0.267
BT 112	CTRP2	7.1531	8.8223	5.4343	1.0574
BT 416	CTRP2	7.3062	8.8351	5.5075	0.7005
BT 131	CTRP2	7.4124	9.2546	5.385	0.9979
BT 232	CTRP2	7.426	15.8955	2.2175	13.2455
BT 498	CTRP2	7.4406	8.4821	5.7036	0.1618
BT 159	CTRP2	7.449	9.1067	5.465	0.726
BT 286	CTRP2	7.5123	9.4132	5.3689	0.9699
BT 422	CTRP2	7.5314	9.3628	5.3994	0.8621
BT147	CTRP2	7.5346	9.5462	5.3241	1.0935
BT 216	CTRP2	7.5512	9.4044	5.3919	0.8705
BT 239	CTRP2	7.5561	11.7145	4.3485	4.682
BT 320	CTRP2	7.5775	8.7842	5.6471	0.2178
BT 340	CTRP2	7.5972	9.04	5.5591	0.3929
BT 224	CTRP2	7.6552	9.2872	5.4882	0.5358
BT 444	CTRP2	7.6727	8.7511	5.6954	0.1164
BT 504	CTRP2	7.6914	11.8941	4.3518	4.4905
BT 359	CTRP2	7.7383	10.105	5.1914	1.3532
BT 428	CTRP2	7.8433	9.2443	5.5837	0.2456
BT164	CTRP2	7.913	9.2536	5.6074	0.1858
BT 248	CTRP2	7.9777	9.4156	5.574	0.2215
BT 328	CTRP2	7.9846	9.121	5.6799	0.08
BT 482	CTRP2	8.0149	9.3052	5.6272	0.1342
BT 179	CTRP2	8.0223	9.1268	5.6911	0.0648
BT 139	CTRP2	8.0617	9.2202	5.6732	0.0757
BT 330	CTRP2	8.1586	21.09	0.2027	18.6837
BT 333	CTRP2	8.1642	9.4989	5.6142	0.1216
BT 440	CTRP2	8.2204	10.5154	5.2573	0.8167
BT 231	CTRP2	8.2616	10.9	5.1209	1.1721
BT 245	CTRP2	8.3363	10.3376	5.377	0.4712
BT 145	CTRP2	8.402	9.7695	5.606	0.0928
BT 228	CTRP2	8.4737	10.3543	5.4264	0.3243
BT 172	CTRP2	8.8558	18.19	2.1248	11.3511
BT 271	CTRP2	10.1794	22.4995	0.9554	13.3938

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	7.4786	8.3928	5.7494	0.0869

Cancer Drug Sensitivity Data Curated from 100 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Daoy	GDSC1; GDSC2	0.4831	3.5719	0.1521	26.6732
GB-1	GDSC1; GDSC2	0.6496	4.1306	0.1506	25.999
GI-1	GDSC1; GDSC2	0.8571	3.8107	0.4842	23.587
D283 Med	GDSC1; GDSC2	1.3074	3.5871	1.0457	19.0793
MOG-G-UVW	GDSC1; GDSC2	1.3306	3.7264	1.0262	19.0829
D-566MG	GDSC1	1.4986	4.5937	0.883	22.1775
SF268	GDSC1; GDSC2	1.7693	4.7441	1.1034	17.0558
H4	GDSC1; GDSC2	2.094	5.6731	1.0136	16.4144
SF539	GDSC1; GDSC2	2.1534	4.9461	1.4081	14.1278
ONS-76	GDSC1; GDSC2	2.2176	6.6495	0.6673	17.826
YKG-1	GDSC1	2.4135	4.7499	1.7587	13.1989
MOG-G-CCM	GDSC1; GDSC2	2.5194	4.6063	1.9304	10.1174
8-MG-BA	GDSC1; GDSC2	2.5573	5.2451	1.6671	11.4181
D-263MG	GDSC1; GDSC2	2.7982	4.9376	2.0447	8.608
AM-38	GDSC1; GDSC2	2.862	4.2187	2.4497	6.2005
SK-MG-1	GDSC1; GDSC2	2.9034	6.1492	1.546	11.0484
D-247MG	GDSC1	2.9116	6.3448	1.4563	13.327
LN-18	GDSC1; GDSC2	2.9309	4.625	2.3214	6.6844
SF295	GDSC1	3.0324	6.2213	1.6245	11.8697
M059J	GDSC1; GDSC2	3.0438	6.7341	1.3789	11.5758
SF126	GDSC1	3.0488	5.7386	1.8791	10.1893
SW1783	GDSC1; GDSC2	3.0729	6.2684	1.6364	10.075
SW1088	GDSC1; GDSC2	3.1961	5.8921	1.9305	8.106
NMC-G1	GDSC1	3.2698	11.2958	-0.7086	23.7144
U-251MG	GDSC1; GDSC2	3.2781	6.2023	1.8451	8.3661
D-392MG	GDSC1; GDSC2	3.3298	5.8598	2.0595	7.036
D-423MG	GDSC1	3.3726	7.4766	1.2866	12.937
DBTRG-05MG	GDSC1; GDSC2	3.457	5.2927	2.4467	4.5565
U-118MG	GDSC1; GDSC2	3.4643	7.0147	1.5928	9.2941
LN-229	GDSC1; GDSC2	3.4804	5.8808	2.172	6.0321
YH-13	GDSC1; GDSC2	3.4854	7.0376	1.5985	9.2101
Hs 683	GDSC1	3.4932	4.8683	2.6865	3.6354
LN-405	GDSC1; GDSC2	3.5039	5.4955	2.3829	4.8002
LNZTA3WT4	GDSC1; GDSC2	3.554	6.2117	2.0656	6.4486
Onda 11	GDSC1	3.5847	9.6322	0.383	17.5386
U-87MG ATCC	GDSC1; GDSC2	3.5954	6.7724	1.819	7.7209
42-MG-BA	GDSC1; GDSC2	3.6551	7.701	1.4035	9.8691
DK-MG	GDSC1; GDSC2	3.7664	5.9941	2.3357	4.4713
D-542MG	GDSC1	3.7908	6.7321	1.9901	7.3249
Becker	GDSC1; GDSC2	3.8015	7.4999	1.6179	8.3497
KNS-42	GDSC1	3.8543	7.209	1.8022	8.3536
D-336MG	GDSC1	3.8896	7.0258	1.9192	7.523
KS-1 [Human Krukenberg tumour]	GDSC1; GDSC2	4.039	7.8596	1.6194	7.8118
PFSK-1	GDSC1; GDSC2	4.1591	9.6489	0.8262	11.7721
D-502MG	GDSC1	4.2815	10.1995	0.6464	14.1666
KALS-1	GDSC1; GDSC2	4.516	10.3855	0.7291	11.4816
SNB-75	GDSC1	4.5808	11.2534	0.3502	14.9955
KINGS-1	GDSC1; GDSC2	4.6807	9.5926	1.2341	8.5412
CAS-1	GDSC1; GDSC2	4.8634	7.4153	2.3723	2.4205
T98G	GDSC1; GDSC2	4.9504	8.9813	1.707	5.5892
A-172	GDSC1; GDSC2	5.236	9.6675	1.5671	5.8216
Onda 10	GDSC1	5.5015	14.3745	-0.5101	16.9334
KNS-81-FD	GDSC1	5.6554	7.8279	2.591	0.9161
D283 Med	CTRP2	6.0398	8.9875	4.569	6.2102
SNU-466	CTRP2	6.0551	10.2257	3.9626	8.7251
GaMG	GDSC1; GDSC2	6.1222	13.9914	0.1017	11.3393
LN-18	CTRP2	7.1228	8.4963	5.5578	0.6826
CCF-STTG1	CTRP2	7.333	8.629	5.6033	0.419
SW1783	CTRP2	7.3412	9.2241	5.3609	1.1362
CAS-1	CTRP2	7.3491	13.2518	3.4618	8.5406
SNU-201	CTRP2	7.4048	8.9065	5.5255	0.5831
SNU-489	CTRP2	7.4749	8.8833	5.5666	0.4355
GMS-10	CTRP2	7.5299	8.5507	5.713	0.1239
GB-1	CTRP2	7.5361	10.6813	4.8197	2.8809
KNS-42	CTRP2	7.5417	9.2263	5.4604	0.6776
U-87MG ATCC	CTRP2	7.6262	8.9782	5.5948	0.3021
SF126	CTRP2	7.6655	18.8726	0.9262	17.3016
SNU-1105	CTRP2	7.6779	8.6704	5.7253	0.0798
KG-1-C	CTRP2	7.7056	8.9868	5.6236	0.2186
Daoy	CTRP2	7.7122	10.2818	5.1011	1.6777
LN-229	CTRP2	7.7126	10.2023	5.1359	1.5593
GaMG	CTRP2	7.7134	9.1472	5.5673	0.3245
SF539	CTRP2	7.7422	9.4819	5.4505	0.5843
SNU-626	CTRP2	7.7504	9.1393	5.5854	0.2742
Becker	CTRP2	7.8361	9.8509	5.346	0.8096
DK-MG	CTRP2	7.8591	9.3428	5.5537	0.2962
Hs 683	CTRP2	7.8924	9.4931	5.5111	0.3697
SF295	CTRP2	7.9061	9.3591	5.5665	0.2562
SNU-738	CTRP2	8.0446	9.731	5.4846	0.3642
NMC-G1	CTRP2	8.058	9.4121	5.6056	0.1535
M059K	CTRP2	8.064	9.4093	5.6088	0.1479
T98G	CTRP2	8.069	9.7381	5.4919	0.3405
YKG-1	CTRP2	8.0982	9.129	5.7163	0.039
TM-31	CTRP2	8.1157	9.1294	5.722	0.0343
U-251MG	CTRP2	8.1271	9.5392	5.5865	0.1644
A-172	CTRP2	8.1473	9.8031	5.4993	0.2991
DBTRG-05MG	CTRP2	8.2208	9.9739	5.4657	0.3366
ONS-76	CTRP2	8.2245	9.8374	5.517	0.2447
AM-38	CTRP2	8.2437	10.082	5.4348	0.3885
YH-13	CTRP2	8.3045	10.0042	5.4876	0.2703
42-MG-BA	CTRP2	8.3847	10.4929	5.3384	0.5346
U-118MG	CTRP2	8.4994	10.3811	5.4268	0.3156
SNB-75	CTRP2	8.5481	10.6437	5.3494	0.4443
SF268	CTRP2	8.5564	10.7948	5.2959	0.5533
8-MG-BA	CTRP2	8.583	10.2691	5.4986	0.1837
SW1088	CTRP2	8.7385	10.3224	5.5362	0.1131
GOS-3	CTRP2	9.2452	10.8552	5.5319	0.0615
KNS-81	CTRP2	10.0963	32.6856	-4.0686	25.3357
KALS-1	CTRP2	11.8885	22.9031	1.8437	8.5437
KNS-60	CTRP2	13.5985	36.6464	-3.511	20.0196

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TGBC1TKB	GDSC1; GDSC2	3.5323	5.2276	2.5382	3.8701
TGBC24TKB	GDSC1; GDSC2	3.8874	5.4463	2.686	2.3384
ETK-1	GDSC1; GDSC2	4.0435	7.4736	1.8124	6.7503

Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ESS-1	GDSC1; GDSC2	1.1095	4.0602	0.6721	21.6825
MFE-296	GDSC1; GDSC2	3.2967	4.2635	2.83	2.8155
AN3-CA	GDSC1; GDSC2	3.3138	6.2445	1.8538	8.225
RL95-2	GDSC1; GDSC2	4.1343	8.5576	1.3464	9.0811
EN	GDSC1; GDSC2	4.185	6.4509	2.405	3.2872
MFE-280	GDSC1; GDSC2	4.7083	7.0733	2.4368	2.3227
KLE	GDSC1; GDSC2	4.7094	7.6261	2.1868	3.5428
MFE-319	GDSC1; GDSC2	6.1598	7.5659	2.8746	0.0669
JHUEM-2	CTRP2	6.3827	8.7892	4.9427	4.0175
KLE	CTRP2	6.9495	10.8688	4.3386	5.5989
HEC-265	CTRP2	7.3658	8.6707	5.6015	0.4061
JHUEM-7	CTRP2	7.4398	9.1373	5.4479	0.7828
HEC-1-B	CTRP2	7.44	9.2167	5.4149	0.8826
HEC-251	CTRP2	7.4902	10.2957	4.9686	2.3762
JHUEM-1	CTRP2	7.6683	8.8433	5.661	0.167
HEC-59	CTRP2	7.803	16.2203	2.3373	12.1802
MFE-296	CTRP2	7.8227	11.1449	4.7795	2.7081
EFE-184	CTRP2	7.8925	9.2477	5.6017	0.2003
AN3-CA	CTRP2	7.9433	9.9239	5.3664	0.6893
HEC-151	CTRP2	7.9779	9.4053	5.5778	0.2152
RL95-2	CTRP2	8.0499	9.3898	5.6104	0.1488
ESS-1	CTRP2	8.0524	9.6748	5.5086	0.314
JHUEM-3	CTRP2	8.0706	10.6333	5.1376	1.2596
HEC-6	CTRP2	8.0765	9.4462	5.6005	0.1565
EN	CTRP2	8.3012	9.8857	5.5289	0.2057
MFE-319	CTRP2	8.4523	9.8914	5.5822	0.1091
HEC-1-A	CTRP2	8.5574	12.6445	4.5286	2.853
HEC-50B	CTRP2	10.6241	23.3971	-0.0035	12.0499
HEC-108	CTRP2	18.2212	44.5649	-4.2616	16.817
Ishikawa (Heraklio) 02 ER-	CTRP2	15.1729	36.4106	-2.3728	16.0614

Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KTCTL-1M	GDSC1	-0.04	4.8998	-0.8728	37.8812
KTCTL-140	GDSC1	0.0228	4.5718	-0.6833	36.8878
LB996-RCC	GDSC1; GDSC2	0.6331	3.9409	-0.0237	21.9034
KTCTL-195	GDSC1; GDSC2	0.9007	4.019	0.461	23.5256
BB65-RCC	GDSC1	1.2001	4.0946	0.7574	24.2132
786-O	GDSC1; GDSC2	1.9296	4.653	1.3086	15.4241
KMRC-20	GDSC1; GDSC2	2.2546	4.4722	1.7222	12.1219
LB1047-RCC	GDSC1	2.3993	5.6263	1.3328	15.8877
OS-RC-2	GDSC1; GDSC2	2.4668	4.7597	1.8073	10.9515
RXF 393L	GDSC1	2.5367	9.3342	-0.3613	24.5978
Caki-1	GDSC1	2.6499	9.1249	-0.157	23.26
SW156	GDSC1	2.7001	5.2085	1.8209	11.7453
ACHN	GDSC1; GDSC2	2.7758	5.7689	1.6181	11.0209
CAL-54	GDSC1; GDSC2	2.9275	6.1773	1.5536	10.938
UO-31	GDSC1	3.0105	6.0302	1.7002	11.4583
LB2241-RCC	GDSC1	3.0395	5.3409	2.0684	9.0029
KTCTL-13	GDSC1	3.1104	7.7033	0.9526	15.77
KTCTL-26A	GDSC1	3.2255	12.5521	-1.3738	26.4337
SW13	GDSC1; GDSC2	3.2501	5.1769	2.334	5.7096
SN12C	GDSC1; GDSC2	3.3245	4.9026	2.5338	4.399
A-498	GDSC1; GDSC2	3.4013	5.2711	2.4127	4.8828
BFTC-909	GDSC1; GDSC2	3.4783	7.7161	1.2538	11.1202
NCC010	GDSC1	3.5136	6.3493	1.9649	8.2334
KTCTL-21	GDSC1	3.9697	6.2664	2.3483	4.6215
VMRC-RCW	GDSC1	4.0478	7.1545	1.9718	8.253
TK-10	GDSC1; GDSC2	4.0829	6.486	2.3204	3.9202
HA7-RCC	GDSC1	4.1198	12.2185	-0.4802	20.2509
VMRC-RCZ	GDSC1; GDSC2	4.3537	6.0293	2.7007	1.5532
769-P	GDSC1; GDSC2	4.6005	12.8322	-0.4143	16.6843
A-704	GDSC1; GDSC2	4.7263	7.7763	2.1279	3.8126
KMRC-1	GDSC1; GDSC2	5.0294	8.8836	1.8026	4.9712
RCC10RGB	GDSC1; GDSC2	5.1636	6.6682	2.8244	0.3986
BFTC-909	CTRP2	6.1245	7.1397	5.562	1.8783
TUHR10TKB	CTRP2	6.4774	7.655	4.6547	0.2552
KMRC-20	CTRP2	7.1598	9.0256	5.3487	1.3473
NCC021	GDSC1	7.2226	16.2733	-0.2634	12.3512
OS-RC-2	CTRP2	7.4549	10.0306	5.0679	2.0504
A-498	CTRP2	7.8588	9.0585	5.6562	0.1288
TUHR4TKB	CTRP2	7.9167	9.1637	5.6406	0.1371
KMRC-1	CTRP2	7.9937	9.2678	5.6325	0.1317
KMRC-2	CTRP2	8.0966	9.1989	5.6925	0.0554
SNU-1272	CTRP2	8.1625	14.1991	3.5684	6.9231
KMRC-3	CTRP2	8.2267	11.1716	4.9899	1.6002
ACHN	CTRP2	8.2322	9.6455	5.5879	0.1405
UO-31	CTRP2	8.2857	14.937	3.2987	7.7968
RCC10RGB	CTRP2	8.3041	9.7304	5.5845	0.1311
Caki-2	CTRP2	8.3612	9.3766	5.7225	0.0204
VMRC-RCW	CTRP2	8.3792	9.9856	5.5228	0.1958
769-P	CTRP2	8.6672	10.74	5.3617	0.3782
CAL-54	CTRP2	8.6762	10.5026	5.4509	0.2287
Caki-1	CTRP2	8.7123	10.4764	5.4735	0.1894
VMRC-RCZ	CTRP2	8.888	10.3637	5.574	0.0644
786-O	CTRP2	8.9984	10.4706	5.5759	0.054

Cancer Drug Sensitivity Data Curated from 92 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SK-CO-1	GDSC1; GDSC2	0.2262	4.3549	-0.3859	30.1475
SNU-175	GDSC2	2.8054	6.5348	0.7906	10.1124
SW620	GDSC1; GDSC2	2.9426	5.1072	2.0963	7.891
C2BBe1	GDSC1; GDSC2	2.9672	4.2879	2.5188	5.4911
SW48	GDSC1; GDSC2	3.1112	5.8638	1.8713	8.6649
MDST8	GDSC1; GDSC2	3.1679	5.1742	2.2645	6.3186
SNU-C5	GDSC1; GDSC2	3.1839	5.3395	2.1959	6.6578
HCT 116	GDSC1; GDSC2	3.1972	5.8895	1.9328	8.09
HCT 15	GDSC1; GDSC2	3.2665	5.1775	2.3476	5.5905
SNU-1040	GDSC1	3.3581	5.0132	1.0279	0.8546
LS513	GDSC1; GDSC2	3.4494	5.9597	2.1077	6.467
LS180	GDSC1; GDSC2	3.5334	7.3376	1.4875	9.7042
HCC2998	GDSC1; GDSC2	3.5959	6.331	2.0392	6.4964
CW-2	GDSC1; GDSC2	3.5959	8.0895	1.1625	11.3228
RKO	GDSC1; GDSC2	3.6026	5.5955	2.4097	4.4225
LS411N	GDSC1; GDSC2	3.8734	5.7052	2.5527	3.0736
SNU-C2B	GDSC1; GDSC2	3.8778	6.5686	2.1353	5.3345
HT115	GDSC1	3.9272	5.5724	2.6524	2.8335
SW626	GDSC1; GDSC2	3.9431	6.4322	2.2491	4.5776
KM12	GDSC1; GDSC2	3.9601	6.032	2.4548	3.4333
SW1417	GDSC1; GDSC2	4.0086	5.7701	2.6119	2.514
LoVo	GDSC1; GDSC2	4.0343	7.7069	1.6911	7.4316
SNU-81	GDSC1	4.057	6.7592	2.1706	5.5336
GP5d	GDSC1; GDSC2	4.1324	7.156	2.0311	5.3799
HT-29	GDSC1; GDSC2	4.1573	5.3717	2.881	0.9763
HT-55	GDSC1; GDSC2	4.1754	5.7836	2.7086	1.7589
SNU-407	GDSC1; GDSC2	4.1773	10.1299	0.6019	12.8759
DiFi	GDSC1; GDSC2	4.1805	7.3137	1.9884	5.515
LS123	GDSC1; GDSC2	4.1956	6.6229	2.3305	3.6596
COLO205	GDSC1; GDSC2	4.2188	8.2858	1.542	7.8478
SW837	GDSC1; GDSC2	4.2634	6.5437	2.4118	3.1178
SNU-61	GDSC1; GDSC2	4.4276	6.1313	2.0123	0.6528
COLO 320HSR	GDSC1; GDSC2	4.5323	8.6858	1.5694	7.0685
LS1034	GDSC1; GDSC2	4.7148	6.6823	2.6114	1.5195
CL-11	GDSC1; GDSC2	4.7983	8.7831	1.702	5.8788
SW1463	GDSC1; GDSC2	4.8043	7.0703	2.4913	1.9473
COLO 678	GDSC1; GDSC2	4.8072	6.4332	2.7609	0.8267
NCI-H716	GDSC1; GDSC2	4.833	11.4095	0.4578	12.1571
RCM-1 [Human ESC]	GDSC1; GDSC2	5.0118	8.7012	1.8762	4.628
SW1116	GDSC1; GDSC2	5.1538	7.3682	2.5447	1.3436
NCI-H508	GDSC1	5.2891	11.5333	0.7174	11.3724
NCI-H747	GDSC1; GDSC2	5.4979	7.4728	2.6599	0.6778
CCK-81	GDSC1; GDSC2	5.5072	7.145	2.7856	0.343
T84	GDSC1; GDSC2	5.7969	8.6241	2.3393	1.5544
SNU-C1	GDSC1; GDSC2	6.0863	7.7445	2.7892	0.1694
CaR-1	GDSC1; GDSC2	6.1413	7.7567	2.8044	0.1392
T84	CTRP2	6.9958	9.8619	4.8585	3.4199
SW948	GDSC1; GDSC2	6.9973	18.1297	-1.2883	15.4402
SK-CO-1	CTRP2	7.0236	14.4931	2.6058	12.4663
SW1116	CTRP2	7.0631	8.4992	4.5766	0.2079
COLO205	CTRP2	7.0715	10.9457	4.388	5.2111
NCI-H508	CTRP2	7.1321	10.2117	4.7826	3.5351
HCC-56	CTRP2	7.1674	8.5315	5.5652	0.6275
HT-55	CTRP2	7.2538	9.6836	5.1066	2.1285
COLO201	CTRP2	7.3086	12.5625	3.7695	7.3632
OUMS-23	CTRP2	7.3334	8.891	5.4977	0.7104
HCT 15	CTRP2	7.4753	9.671	5.239	1.4259
LS1034	CTRP2	7.4793	9.1194	5.4743	0.6789
LS513	CTRP2	7.4834	9.5688	5.2877	1.255
LS411N	CTRP2	7.5204	8.5503	5.7095	0.1312
GP2d	CTRP2	7.5387	9.3349	5.4145	0.8119
LS123	CTRP2	7.5407	9.6698	5.2745	1.2491
CW-2	CTRP2	7.5687	9.5151	4.4051	0.3557
C2BBe1	CTRP2	7.5909	13.8555	3.3406	8.6477
HCT 8	CTRP2	7.6608	8.884	5.6435	0.1979
SNU-C4	CTRP2	7.6761	8.6697	5.7249	0.0805
HT115	CTRP2	7.698	9.0283	5.6053	0.2546
SW48	CTRP2	7.7195	11.5369	4.537	3.7382
RKO	CTRP2	7.7627	13.1556	3.7988	6.5743
SNU-C5	CTRP2	7.7781	10.3362	5.113	1.5777
CL-11	CTRP2	7.8133	13.3972	3.7173	6.8255
SNU-407	CTRP2	7.8428	9.7848	5.3758	0.7234
SNU-1033	CTRP2	7.874	15.2247	2.8752	10.0328
SNU-C1	CTRP2	7.8921	11.183	4.8026	2.5502
MDST8	CTRP2	7.9536	9.4007	5.57	0.2353
KM12	CTRP2	8.2233	10.943	5.0843	1.3087
SW620	CTRP2	8.2297	9.6048	5.6011	0.1251
RCM-1 [Human ESC]	CTRP2	8.2771	9.4277	5.6778	0.0487
SNU-61	CTRP2	8.2831	10.1262	5.4344	0.3746
COLO 320	CTRP2	8.314	11.5165	4.8881	1.8567
LS180	CTRP2	8.3461	9.5866	5.6483	0.0633
COLO 678	CTRP2	8.3502	10.1318	5.4591	0.3056
NCI-H716	CTRP2	8.3663	11.6359	4.8644	1.89
SW1417	CTRP2	8.3681	10.4285	5.3558	0.5034
SW948	CTRP2	8.3925	17.5401	2.1164	12.0667
SNU-503	CTRP2	8.5194	10.0314	5.558	0.124
CCK-81	CTRP2	8.6661	10.2983	5.5187	0.143
LoVo	CTRP2	8.8021	10.909	5.3531	0.3502
SNU-C2A	CTRP2	8.9595	10.9828	5.3869	0.2535
HCT 116	CTRP2	12.8281	34.2734	-2.8951	19.7016
DLD-1	CTRP2	13.0761	34.3066	-2.7432	19.1053
HT-29	CTRP2	13.4457	34.8424	-2.7517	18.7004

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1; GDSC2	4.0023	7.9858	1.5299	8.3789

Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-6	GDSC1; GDSC2	2.2382	5.7702	1.1086	15.4423
HLE	GDSC1; GDSC2	2.6383	4.759	1.9766	9.4807
JHH-4	GDSC1; GDSC2	2.9727	4.5668	2.3889	6.1871
HuH-1	GDSC1; GDSC2	3.0111	5.9576	1.7369	9.6884
JHH-7	GDSC1; GDSC2	3.2018	6.0471	1.8579	8.4953
Hep 3B2.1-7	GDSC1	3.29	4.6462	2.633	4.5598
SNU-398	GDSC1; GDSC2	3.3288	4.7954	2.5909	4.0689
SNU-387	GDSC1; GDSC2	3.7003	5.9918	2.2877	4.8796
JHH-1	GDSC1; GDSC2	3.9797	5.4247	2.755	1.8253
JHH-2	GDSC1; GDSC2	4.2311	6.5341	2.3956	3.2565
SK-HEP-1	GDSC1; GDSC2	4.2629	7.1994	2.1002	4.7569
SNU-449	GDSC1; GDSC2	4.4265	6.6691	2.4548	2.6385
SNU-423	GDSC1; GDSC2	4.8355	10.0412	1.1248	8.8034
Hep-G2/C3A	GDSC1; GDSC2	5.0185	7.9146	2.2379	2.8463
Huh-7	GDSC1; GDSC2	5.4824	12.8651	0.2088	12.0375
JHH-6	CTRP2	7.3209	8.2647	5.7358	0.1429
Hep-G2	CTRP2	7.3985	8.7165	5.5981	0.3975
SNU-398	CTRP2	7.4128	9.4483	4.367	0.4941
SK-HEP-1	CTRP2	7.5505	9.0625	5.5299	0.4869
JHH-1	CTRP2	7.8875	9.2211	5.6093	0.1896
HLF	CTRP2	8.0629	9.5461	5.5597	0.2206
Hep 3B2.1-7	CTRP2	8.1799	9.5729	5.5941	0.143
SNU-387	CTRP2	8.2208	10.4774	5.2726	0.7763
HuH-1	CTRP2	8.2692	9.5578	5.6313	0.087
SNU-475	CTRP2	8.2717	9.5184	5.6455	0.0739
JHH-4	CTRP2	8.2764	10.1308	5.4299	0.3858
Li-7	CTRP2	8.3048	10.9764	5.1104	1.1731
PLC/PRF/5	CTRP2	8.3543	9.7786	5.586	0.1207
SNU-423	CTRP2	8.3976	9.8512	5.5765	0.1239
HuH-6	CTRP2	8.3988	10.4312	5.3677	0.4654
JHH-2	CTRP2	8.4087	9.8413	5.5838	0.1141
JHH-5	CTRP2	8.7051	10.2905	5.5353	0.1189
SNU-449	CTRP2	8.8853	10.5587	5.5074	0.1202
SNU-182	CTRP2	9.2087	10.8163	5.5324	0.0641
SNU-761	CTRP2	13.7594	37.8218	-3.9654	20.6792

Cancer Drug Sensitivity Data Curated from 321 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H209	GDSC1; GDSC2	-0.9203	5.4603	-2.0273	40.7745
NCI-H1975	CTRP2	-0.871	9.0238	-2.4838	47.322
LC-1F	CTRP2	-0.5677	11.7592	-7.6847	30.0438
NCI-H1876	GDSC1; GDSC2	0.0731	3.1435	-0.1765	29.8997
NCI-H2023	GDSC1; GDSC2	0.8481	5.0585	0.0084	25.8719
COR-L311	GDSC2	1.303	4.5823	0.3872	17.119
NCI-H526	GDSC1; GDSC2	1.4215	3.7765	1.1081	18.325
ABC-1	GDSC1	1.5636	8.9212	-1.0506	31.0022
NCI-H1781	GDSC1; GDSC2	1.6154	4.7264	0.9506	18.3927
SBC-3	GDSC1; GDSC2	1.7859	5.8509	0.626	19.4557
COR-L32	GDSC1; GDSC2	1.8276	6.0066	0.2082	16.336
COR-L279	GDSC1; GDSC2	1.9048	4.3675	1.4029	15.0239
NCI-H1105	GDSC1	1.9321	4.4376	1.4024	17.2991
HCC366	GDSC1	1.9592	6.121	0.6711	21.4812
HCC44	GDSC1; GDSC2	1.9603	5.0987	1.144	16.1776
COR-L23	GDSC1; GDSC2	2.2955	5.9651	1.071	15.4594
HOP-92	GDSC1; GDSC2	2.3319	6.4327	0.8803	16.3554
HOP-62	GDSC1; GDSC2	2.3373	4.7474	1.6834	12.0449
NCI-H290	GDSC1	2.3466	5.5561	1.3155	16.1902
NCI-H460	GDSC1	2.4046	3.8532	2.1384	10.9249
NCI-H23	GDSC1; GDSC2	2.419	4.8823	1.7031	11.6679
NCI-H2810	GDSC1	2.4295	5.5579	1.3945	15.396
NCI-H1341	GDSC1; GDSC2	2.4364	4.8381	1.7408	11.4084
NCI-H1651	GDSC1; GDSC2	2.4782	6.0622	1.1978	14.2089
NCI-H1437	GDSC1	2.5056	5.1256	1.674	13.3771
NCI-H1155	GDSC1; GDSC2	2.5411	5.0026	1.7668	10.9286
NCI-H1963	GDSC1; GDSC2	2.5448	6.0186	1.2815	13.5525
SK-LU-1	GDSC1; GDSC2	2.5506	5.3381	1.6161	11.7164
NCI-H2369	GDSC1; GDSC2	2.6303	6.6751	1.039	14.6032
NCI-H2110	GDSC1	2.6586	5.1446	1.8122	11.9494
NCI-H1694	GDSC1; GDSC2	2.7091	4.6949	2.0758	8.717
NCI-H1734	GDSC1	2.7181	4.7843	2.042	12.5127
NCI-H2030	GDSC1	2.7183	5.7383	1.58	13.2031
NCI-H82	GDSC1; GDSC2	2.7208	8.3899	0.271	18.3022
COLO 668	GDSC1; GDSC2	2.7534	6.3164	1.328	12.6773
A-549	GDSC1; GDSC2	2.8118	5.0353	2.0102	8.7563
LC-2/ad	GDSC1	2.867	6.2737	1.4517	13.5042
Lu-99A	GDSC1; GDSC2	2.885	5.195	2.0003	8.5914
DMS 273	GDSC1; GDSC2	3.0262	7.44	1.0115	13.6198
NCI-H2228	GDSC1; GDSC2	3.0325	7.5045	0.9848	13.7459
BEN	GDSC1	3.0482	6.0759	1.7107	11.2696
NCI-H513	GDSC1; GDSC2	3.0494	7.0546	1.2238	12.4087
NCI-H2804	GDSC1	3.0648	5.016	2.2521	7.7369
NCI-H1792	GDSC1; GDSC2	3.0741	5.7627	1.8893	8.6666
ChaGo-K-1	GDSC1	3.1024	5.5365	2.0267	9.0676
PC-14	GDSC1; GDSC2	3.117	5.0431	2.2851	6.3443
EPLC-272H	GDSC1; GDSC2	3.1277	6.9696	1.3338	11.5949
Lu-134-A	GDSC1	3.1452	5.6162	2.0244	8.9464
DMS 79	GDSC1	3.1685	5.2207	2.2418	7.469
NCI-H1355	GDSC1; GDSC2	3.1781	6.0112	1.8556	8.5713
LB647-SCLC	GDSC1	3.1795	7.0789	0.8122	10.5521
NCI-H2122	GDSC1; GDSC2	3.1806	5.5641	2.081	7.3076
NCI-H2227	GDSC1	3.1906	6.0738	1.835	10.0239
NCI-H1048	GDSC1; GDSC2	3.1928	5.7134	2.017	7.6322
NCI-H2087	GDSC1; GDSC2	3.202	6.5587	1.6025	9.9145
NCI-H524	GDSC1; GDSC2	3.2298	7.7328	1.0393	12.9214
NCI-H510A	GDSC1	3.2368	7.9609	0.9311	18.4972
NCI-H650	GDSC1; GDSC2	3.241	5.499	2.1653	6.6762
NCI-H1581	GDSC1; GDSC2	3.2621	5.5034	2.1809	6.5335
NCI-H1650	GDSC1; GDSC2	3.2815	4.401	2.7484	3.3114
NCI-H196	GDSC1; GDSC2	3.2869	5.1011	2.403	5.2275
NCI-H1793	GDSC1; GDSC2	3.291	4.3145	2.7996	3.0001
RERF-LC-MS	GDSC1	3.3119	4.5864	2.6813	4.1808
NCI-H647	GDSC1	3.319	6.5748	1.6931	10.5417
NCI-H838	GDSC1	3.3293	4.9666	2.5058	5.2665
EMC-BAC-2	GDSC1; GDSC2	3.3358	7.7879	1.1005	12.3142
NCI-H2170	GDSC1; GDSC2	3.3519	6.8229	1.5964	9.5582
NCI-H661	GDSC1; GDSC2	3.3671	5.1481	2.4462	4.7808
LCLC-103H	GDSC1; GDSC2	3.3865	4.4753	2.7981	2.7668
RERF-LC-KJ	GDSC1; GDSC2	3.4164	5.1086	2.5061	4.3238
Lu-135	GDSC1; GDSC2	3.4226	6.9356	1.5983	9.368
NCI-H841	GDSC1; GDSC2	3.4887	5.9249	2.1567	6.0977
NCI-H187	GDSC1	3.4918	5.2476	2.4968	4.8622
NCI-H1666	GDSC1; GDSC2	3.5105	6.2239	2.025	6.7792
A-427	GDSC1	3.5403	5.0953	2.61	4.0029
HARA [Human squamous cell lung carcinoma]	GDSC1; GDSC2	3.5441	6.1808	2.0732	6.4297
KNS-62	GDSC1; GDSC2	3.5917	7.2014	1.6021	8.9303
NCI-H720	GDSC1; GDSC2	3.6418	4.71	2.873	1.7975
COR-L95	GDSC1; GDSC2	3.6542	6.6436	1.9292	6.9705
NCI-H2795	GDSC1; GDSC2	3.6562	6.2728	2.115	5.9354
SBC-5	GDSC1; GDSC2	3.7073	6.1381	2.2206	5.2348
NCI-H2405	GDSC1; GDSC2	3.7115	6.198	2.1942	5.3716
HCC827	GDSC1; GDSC2	3.7281	7.1686	1.7257	7.9249
NCI-H1688	GDSC1; GDSC2	3.7359	5.2216	2.691	2.5951
IST-SL2	GDSC1; GDSC2	3.7626	5.6403	2.5063	3.5448
NCI-H1944	GDSC1; GDSC2	3.7713	7.8946	1.3984	9.6208
SBC-1	GDSC1	3.7756	5.9667	2.3559	5.0318
CPC-N	GDSC1; GDSC2	3.7833	6.4814	2.1083	5.6871
NCI-H2066	GDSC1; GDSC2	3.7899	5.8275	2.4345	3.881
NCI-H1304	GDSC1	3.7969	7.5439	1.5925	9.8264
NCI-H211	GDSC1; GDSC2	3.8195	7.5022	1.6306	8.2384
NCI-H1623	GDSC1; GDSC2	3.8243	9.181	0.7998	12.6899
NCI-H146	GDSC1	3.8653	6.2782	1.6647	3.3091
DMS 114	GDSC1; GDSC2	3.8673	6.8485	1.99	6.1551
LOU-NH91	GDSC1; GDSC2	3.8687	6.1966	2.3109	4.3931
NCI-H345	GDSC1; GDSC2	3.8688	5.6009	2.5997	2.8304
NCI-H226	GDSC1; GDSC2	3.8696	5.7698	2.5189	3.2627
NCI-H520	GDSC1; GDSC2	3.9042	6.9675	1.9587	6.2475
LCLC-97TM1	GDSC1; GDSC2	3.9077	8.2715	1.3168	9.7477
LK-2	GDSC1; GDSC2	3.915	8.0535	1.4304	9.115
Ms-1	GDSC1; GDSC2	3.9306	7.0317	1.9467	6.2566
NCI-H810	GDSC1; GDSC2	3.932	6.0314	2.4357	3.5896
NCI-H3122	GDSC1; GDSC2	3.9789	5.9808	2.4921	3.1985
NCI-H1299	GDSC1; GDSC2	3.9868	10.374	0.3335	14.6559
NCI-H1869	GDSC1; GDSC2	4.0051	6.2107	2.3996	3.6432
NCI-H64	GDSC1; GDSC2	4.0244	5.732	1.9876	1.0735
EBC-1	GDSC1; GDSC2	4.0482	5.9665	2.5449	2.7947
HCC78	GDSC1; GDSC2	4.0527	7.667	1.7243	7.2112
EMC-BAC-1	GDSC1	4.0729	9.4199	0.874	13.43
SW1271	GDSC1; GDSC2	4.0766	5.9985	2.5482	2.7285
NCI-H2085	GDSC1; GDSC2	4.0855	6.2607	2.4298	3.3337
NCI-H2141	GDSC1; GDSC2	4.1141	9.9042	0.6654	12.6991
Calu-6	GDSC1; GDSC2	4.1352	6.7323	2.2377	4.2635
Lu-139	GDSC1; GDSC2	4.1402	7.7941	1.7257	7.0191
NCI-H358	GDSC1; GDSC2	4.1421	6.8055	2.2072	4.4135
NCI-H522	GDSC1; GDSC2	4.1637	11.0362	-0.4081	13.3951
NCI-H2081	GDSC1	4.1671	11.5765	-0.6701	16.6127
IST-SL1	GDSC1	4.1819	6.2675	2.4893	3.3085
LXF 289	GDSC1; GDSC2	4.1865	7.8863	1.714	6.9861
LC-1/sq	GDSC1; GDSC2	4.2157	10.8418	0.2784	14.3861
NCI-H1755	GDSC1; GDSC2	4.2518	6.2457	2.5432	2.4656
SW1573	GDSC1; GDSC2	4.2636	6.9182	2.2351	4.0404
VMRC-LCD	GDSC1; GDSC2	4.2784	6.608	2.3912	3.1989
IA-LM	GDSC1; GDSC2	4.2933	8.1838	1.6453	7.1383
NCI-H3255	GDSC1	4.321	6.9665	2.2498	4.4743
NCI-H2342	GDSC1; GDSC2	4.3362	7.0414	2.2243	3.9677
NCI-H1092	GDSC1; GDSC2	4.3475	6.9626	2.2689	3.7153
SK-MES-1	GDSC1; GDSC2	4.4037	7.659	1.9751	5.1595
NCI-H1573	GDSC1; GDSC2	4.4272	5.8298	2.8253	0.9218
COR-L88	GDSC1; GDSC2	4.4771	6.4795	2.5702	2.0028
NCI-H1693	GDSC1; GDSC2	4.4817	8.0009	1.8641	5.6028
NCI-H1975	GDSC1; GDSC2	4.5036	8.3679	1.7029	6.4158
NCI-H2595	GDSC1; GDSC2	4.5079	8.1435	1.8135	5.822
NCI-H2722	GDSC1; GDSC2	4.5394	10.0243	0.9232	10.441
NCI-H1648	GDSC1; GDSC2	4.566	8.414	1.7232	6.1907
NCI-H446	GDSC1; GDSC2	4.5809	8.5126	1.686	6.3593
NCI-H2731	GDSC1; GDSC2	4.6047	8.5301	1.6937	6.2738
NCI-H2461	GDSC1; GDSC2	4.6253	9.4737	1.2529	8.553
NCI-H835	GDSC1; GDSC2	4.6306	7.4747	2.2084	3.558
NCI-H2172	GDSC1	4.6681	8.7991	1.6078	7.6297
NCI-H69	GDSC1; GDSC2	4.6908	7.6796	2.1508	3.7536
SHP-77	GDSC1; GDSC2	4.7084	8.3601	1.8434	5.3024
NCI-H2373	GDSC1; GDSC2	4.7188	7.5237	2.2395	3.2656
RERF-LC-Sq1	GDSC1; GDSC2	4.7273	10.4027	0.8734	10.3062
NCI-H2291	GDSC1	4.7849	7.1041	2.4659	2.4193
NCI-H1703	GDSC1; GDSC2	4.8075	7.3398	2.3743	2.485
NCI-H596	GDSC1; GDSC2	4.8149	7.2941	2.3988	2.36
COR-L105	GDSC1; GDSC2	4.8645	12.0629	0.1609	13.5104
NCI-H2444	GDSC1	4.8885	6.0746	2.9331	0.2964
NCI-H1563	GDSC1; GDSC2	4.9099	10.6843	0.8655	9.9785
NCI-H2818	GDSC1; GDSC2	4.9421	12.1506	0.1743	13.284
NCI-H1436	GDSC1	4.9495	6.7904	1.9797	0.5378
NCI-H1836	GDSC1	4.9941	6.7843	2.7065	1.0109
NCI-H727	GDSC1; GDSC2	5.0171	7.4249	2.4515	1.874
PaCa-3	GDSC1; GDSC2	5.0624	8.6896	1.9126	4.3668
NCI-H2029	GDSC1; GDSC2	5.0782	6.4596	2.8672	0.3309
Calu-3	GDSC1; GDSC2	5.0874	7.609	2.4094	1.9777
NCI-H441	GDSC1; GDSC2	5.1015	8.9978	1.7943	4.8967
Lu-65	GDSC1; GDSC2	5.1587	9.2039	1.7343	5.1069
DMS 53	GDSC1; GDSC2	5.1719	8.3379	2.1363	3.1196
NCI-H2347	GDSC1; GDSC2	5.1739	7.934	2.315	2.2942
NCI-H2135	GDSC1	5.181	6.6546	2.8364	0.4179
NCI-H322M	GDSC1; GDSC2	5.2384	7.8357	2.3912	1.8888
NCI-H847	GDSC1; GDSC2	5.2482	7.0905	2.6996	0.7115
NCI-H292	GDSC1	5.2902	7.4906	2.56	1.3482
Lu-165	GDSC1; GDSC2	5.2947	9.1592	1.8374	4.3855
EKVX	GDSC1	5.3917	7.7443	2.505	1.486
NCI-H2009	GDSC1; GDSC2	5.5013	12.3138	0.487	10.6941
UMC-11	GDSC1; GDSC2	5.5087	7.5242	2.6448	0.7167
NCI-H1838	GDSC1; GDSC2	5.5986	8.1995	2.418	1.4301
NCI-H2869	GDSC1	5.6099	12.984	0.2391	13.162
NCI-H1435	GDSC1; GDSC2	5.648	7.1074	2.8516	0.1747
COR-L321	GDSC1	5.6575	7.39	2.7552	0.4083
NCI-H2803	GDSC1	5.8144	7.9171	2.6239	0.701
NCI-H1993	GDSC1; GDSC2	5.8211	8.1582	2.5351	0.8588
HCC15	GDSC1; GDSC2	5.8222	11.3512	1.1504	6.9295
NCI-H2085	CTRP2	5.8411	9.9214	3.2338	6.6423
CAL-12T	GDSC1	5.8818	8.0927	2.5857	0.7814
NCI-H1184	CTRP2	5.9089	13.1302	2.388	15.3971
NCI-H2591	GDSC1; GDSC2	5.9391	7.8713	2.6902	0.3875
NCI-H1915	GDSC1; GDSC2	6.0152	13.1824	0.415	10.1021
NCI-H1770	GDSC1	6.0406	7.4947	2.8578	0.1108
NCI-H1341	CTRP2	6.3364	7.682	5.4544	1.97
Calu-6	CTRP2	6.6427	9.8662	4.6063	4.9833
LOU-NH91	CTRP2	6.886	9.0768	4.2776	1.0422
NCI-H446	CTRP2	6.9117	9.2042	4.2375	1.1503
NCI-H1734	CTRP2	6.9334	10.7782	4.3713	5.4897
NCI-H2106	CTRP2	7.0532	10.9323	4.3816	5.2644
HCC1195	CTRP2	7.0866	9.1087	4.3578	0.6778
RERF-LC-A1	CTRP2	7.2174	9.4562	5.1885	1.8654
LK2	CTRP2	7.2259	8.0859	5.7636	0.1244
NCI-H1105	CTRP2	7.2467	9.1762	5.3306	1.3256
NCI-H2087	CTRP2	7.2582	10.3786	4.7861	3.3537
NCI-H522	CTRP2	7.2608	9.6603	5.1214	2.0655
NCI-H526	CTRP2	7.2617	9.395	5.2419	1.6241
RERF-LC-Ad1	CTRP2	7.2726	8.3395	5.6888	0.2481
DMS 273	CTRP2	7.3667	9.209	5.3808	1.0489
NCI-H810	CTRP2	7.3989	8.9013	5.5248	0.5887
LCLC-97TM1	CTRP2	7.4857	9.7403	5.2143	1.5007
NCI-H69	CTRP2	7.4864	10.5265	4.8606	2.7845
NCI-H889	CTRP2	7.5254	19.1006	-0.0386	16.6342
DMS 53	CTRP2	7.5497	12.8265	3.8111	6.8327
SW1573	CTRP2	7.5938	9.7164	4.3409	0.4757
LC-1/sq-SF	CTRP2	7.629	9.0836	5.556	0.3853
Calu-3	CTRP2	7.6346	10.5368	4.9443	2.3087
NCI-H2291	CTRP2	7.6361	10.6378	4.8995	2.4706
NCI-H358	CTRP2	7.6916	16.416	2.1591	13.0182
NCI-H1155	CTRP2	7.7166	9.2461	5.5311	0.4018
HCC15	CTRP2	7.7322	9.9099	5.271	1.1048
NCI-H1650	CTRP2	7.7361	9.6558	4.419	0.2799
LCLC-103H	CTRP2	7.7508	16.0614	2.377	12.1163
NCI-H2126	CTRP2	7.7531	9.1412	5.5857	0.2726
HCC1833	CTRP2	7.7605	9.8869	5.2947	1.0111
NCI-H2029	CTRP2	7.7721	9.3774	5.5044	0.4372
DMS 114	CTRP2	7.7955	10.6337	4.9925	1.9736
NCI-H1435	CTRP2	7.8113	10.4294	5.0904	1.6239
DV-90	CTRP2	7.8352	9.7894	5.3704	0.7425
SHP-77	CTRP2	7.8572	9.304	5.5673	0.271
NCI-H2141	CTRP2	7.8646	9.7669	5.393	0.6647
NCI-H1339	CTRP2	7.877	9.4946	5.5042	0.3909
LUDLU-1	CTRP2	7.8891	13.3994	3.7674	6.5212
NCI-H2081	CTRP2	7.8972	9.5963	5.474	0.449
VMRC-LCD	CTRP2	7.9487	9.4525	5.5492	0.2738
HCC1438	CTRP2	7.9619	10.0919	5.3076	0.8368
Lu-99	CTRP2	7.9687	12.5063	4.2417	4.5649
NCI-H2122	CTRP2	7.9689	9.5536	5.5199	0.3222
NCI-H1568	CTRP2	7.9841	11.2694	4.8165	2.4065
SK-LU-1	CTRP2	7.9894	12.0013	4.4885	3.6012
NCI-H1092	CTRP2	7.9944	9.4382	5.5723	0.2195
COR-L88	CTRP2	8.0034	9.6243	5.5076	0.3338
HOP-62	CTRP2	8.0054	9.9174	5.3967	0.5791
NCI-H650	CTRP2	8.0268	9.7295	5.4778	0.3851
NCI-H647	CTRP2	8.0349	10.3945	5.219	1.0413
COR-L95	CTRP2	8.0408	9.5	5.5678	0.2137
NCI-H196	CTRP2	8.0418	9.287	5.6433	0.1096
NCI-H1869	CTRP2	8.0695	9.8306	5.4574	0.4106
HCC78	CTRP2	8.0971	9.8473	5.4625	0.3888
HCC2935	CTRP2	8.1273	10.1714	5.3513	0.6276
NCI-H2009	CTRP2	8.1288	9.7744	5.5024	0.2995
RERF-LC-Ad2	CTRP2	8.1345	9.4663	5.6147	0.1264
DMS 79	CTRP2	8.1429	9.7135	5.5302	0.2464
NCI-H1573	CTRP2	8.1623	9.7295	5.5319	0.2378
COR-L105	CTRP2	8.1822	10.4086	5.2824	0.7727
NCI-H727	CTRP2	8.1943	9.7134	5.5499	0.201
NCI-H23	CTRP2	8.1957	10.1188	5.401	0.479
NCI-H2286	CTRP2	8.2023	9.815	5.5165	0.2519
NCI-H1755	CTRP2	8.2119	9.8857	5.4945	0.2867
NCI-H1581	CTRP2	8.2131	9.9817	5.4597	0.3507
Sq-1	CTRP2	8.2133	9.509	5.6282	0.0981
HCC366	CTRP2	8.2177	9.9779	5.463	0.3428
ChaGo-K-1	CTRP2	8.2493	10.0031	5.4663	0.3255
NCI-H1355	CTRP2	8.2542	10.9845	5.0823	1.292
HCC95	CTRP2	8.2569	9.8198	5.5357	0.2067
COR-L51	CTRP2	8.2843	9.7885	5.557	0.1698
NCI-H1693	CTRP2	8.2855	10.0121	5.4774	0.2938
NCI-H838	CTRP2	8.2874	9.4196	5.6839	0.0439
NCI-H1299	CTRP2	8.3014	10.3568	5.355	0.5346
NCI-H520	CTRP2	8.3027	10.1378	5.438	0.3605
HCC1171	CTRP2	8.3145	9.9124	5.5245	0.209
NCI-H841	CTRP2	8.3314	10.6007	5.2736	0.7132
NCI-H146	CTRP2	8.3338	9.742	5.5912	0.1183
NCI-H661	CTRP2	8.3371	11.2928	4.055	0.7964
NCI-H2196	CTRP2	8.3431	9.7753	5.583	0.1259
NCI-H1703	CTRP2	8.3722	10.5276	5.3198	0.5823
NCI-H2023	CTRP2	8.3784	10.0734	5.4912	0.2436
NCI-H1915	CTRP2	8.3853	9.72	5.6169	0.0849
NCI-H441	CTRP2	8.394	10.1673	5.4633	0.2848
NCI-H1395	CTRP2	8.3993	14.6602	3.5055	6.8478
T3M-10	CTRP2	8.402	10.0272	5.5166	0.1993
NCI-H1563	CTRP2	8.4085	10.0169	5.5227	0.1893
HARA [Human squamous cell lung carcinoma]	CTRP2	8.4204	10.2381	5.4479	0.3034
NCI-H1694	CTRP2	8.4353	10.0758	5.5118	0.1983
NCI-H2030	CTRP2	8.4453	9.9857	5.5471	0.1497
NCI-H1666	CTRP2	8.4517	10.4552	5.3804	0.4187
HCC2279	CTRP2	8.4655	10.3679	5.4182	0.3417
NCI-H292	CTRP2	8.4826	10.1017	5.5203	0.1763
NCI-H1623	CTRP2	8.4967	10.4882	5.3864	0.3906
NCI-H322	CTRP2	8.5034	10.01	5.5597	0.1248
KNS-62	CTRP2	8.505	9.6882	5.6683	0.037
COLO 668	CTRP2	8.517	10.2282	5.4885	0.2125
NCI-H2172	CTRP2	8.5508	10.3647	5.4526	0.258
LXF 289	CTRP2	8.5591	10.4122	5.4387	0.2779
COLO 699	CTRP2	8.5593	10.1268	5.5395	0.1379
EBC-1	CTRP2	8.5737	10.2177	5.5131	0.1669
NCI-H1792	CTRP2	8.6018	10.3087	5.4916	0.189
SK-MES-1	CTRP2	8.6173	10.4665	5.4415	0.2577
HCC827	CTRP2	8.6283	10.2262	5.53	0.1368
NCI-H1838	CTRP2	8.6295	10.34	5.4909	0.1841
HCC4006	CTRP2	8.6443	10.1653	5.5565	0.1066
NCI-H2170	CTRP2	8.6457	10.1644	5.5573	0.1056
NCI-H1373	CTRP2	8.6734	10.4643	5.4634	0.2116
NCI-H2342	CTRP2	8.6788	10.2545	5.5383	0.1198
DMS 454	CTRP2	8.728	11.5337	5.0835	0.9813
RERF-LC-MS	CTRP2	8.7307	10.4022	5.5061	0.1462
NCI-H211	CTRP2	8.7476	10.1951	5.5823	0.0719
NCI-H1793	CTRP2	8.7656	10.6259	5.4407	0.2223
Lu-65	CTRP2	8.7695	10.4015	5.5201	0.1247
NCI-H1944	CTRP2	8.8124	10.6183	5.4606	0.1856
EPLC-272H	CTRP2	8.8258	10.8979	5.3663	0.3207
NCI-H1651	CTRP2	8.845	10.8116	5.4046	0.2554
HCC2108	CTRP2	8.9933	10.6496	5.5144	0.0994
NCI-H1568	GDSC1; GDSC2	8.9936	17.6815	0.1362	7.009
EKVX	CTRP2	9.0022	11.2064	5.3231	0.3415
NCI-H2405	CTRP2	9.0229	10.8195	5.467	0.1408
HCC44	CTRP2	9.2007	10.9628	5.4807	0.1034
SW1271	CTRP2	9.2456	22.0617	0.5215	16.0413
Calu-1	CTRP2	9.3665	19.2032	1.9852	11.1222
NCI-H2110	CTRP2	9.4482	11.6966	5.3169	0.2406
HOP-92	CTRP2	9.7503	19.0479	2.3108	9.4801
NCI-H2444	CTRP2	10.3939	44.8405	-9.8588	32.2424
HCC1588	CTRP2	10.6303	21.0703	1.9226	9.7088
PC-14	CTRP2	10.6565	26.6248	-0.7018	17.4452
SBC-5	CTRP2	10.7753	24.5318	0.3839	14.3167
NCI-H226	CTRP2	11.4027	31.6983	-2.6378	20.9234
BEN	CTRP2	11.8087	32.1569	-2.576	20.2826
NCI-H2228	CTRP2	12.2093	37.6544	-4.9639	24.1486
CAL-12T	CTRP2	12.5657	31.996	-1.9815	18.0827
NCI-H460	CTRP2	12.8649	26.167	0.9388	10.2428
A-549	CTRP2	14.9456	31.1775	-0.1078	11.0052
MOR/CPR	CTRP2	15.5144	37.3091	-2.577	16.1432
Hs 888.Lu	CTRP2	7.7401	10.424	5.0541	1.8128

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1; GDSC2	4.6811	7.1014	2.4087	2.4937

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
H-STS	CTRP2	6.1726	9.1415	4.6013	5.8226
P-STS	CTRP2	6.9642	11.3615	4.108	6.5222
SYO-1	CTRP2	7.5997	9.7995	5.2498	1.2798

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	7.5646	8.7901	5.6398	0.2358
Aska-SS	CTRP2	8.0737	19.3907	0.9777	16.4535
SW872	GDSC1; GDSC2	0.9382	3.409	0.6963	22.2448
VA-ES-BJ	GDSC1; GDSC2	1.273	4.102	0.833	20.2592
EW-8	GDSC1; GDSC2	1.4055	3.1654	1.271	17.5998
G-402	GDSC1; GDSC2	1.5226	5.3148	0.6017	20.4966
Hs 633.T	GDSC1; GDSC2	1.9968	4.743	1.339	15.0296
G-401	GDSC1; GDSC2	2.0618	5.36	1.1272	15.9221
KYM-1	GDSC1; GDSC2	2.1836	3.9721	1.8568	11.6771
MES-SA	GDSC1; GDSC2	2.7399	5.7098	1.614	11.1499
SK-LMS-1	GDSC1; GDSC2	2.8937	5.8795	1.6708	10.3869
SW982	GDSC1; GDSC2	2.928	7.6998	0.7966	15.0337
MFH-ino	GDSC1; GDSC2	2.9356	4.7198	2.2797	6.8995
HT-1080	GDSC1; GDSC2	2.9542	4.0424	2.6229	4.9665
GCT	GDSC1; GDSC2	3.0228	8.0965	0.681	15.3739
RD	GDSC1; GDSC2	3.2156	7.5999	1.0937	12.6661
A-204	GDSC1; GDSC2	3.2277	6.2617	1.7728	8.9008
RKN	GDSC1; GDSC2	3.2368	3.9824	2.9183	2.4849
SK-UT-1	GDSC1; GDSC2	3.3042	6.4015	1.7674	8.7311
Rh41	GDSC1; GDSC2	3.3347	4.7417	2.6227	3.8762
Rh30	GDSC1; GDSC2	3.4292	6.9257	1.6087	9.2942
STS-0421	GDSC1	3.7185	8.1069	1.2514	12.1546
SW684	GDSC1; GDSC2	4.8845	6.0847	2.9279	0.2694
Rh18	GDSC1	4.9891	8.1782	2.1023	4.0994
RKN	CTRP2	6.6852	9.1416	4.9918	3.3301
TE 441.T	CTRP2	6.7731	9.4021	4.9272	3.4619
BT-12	CTRP2	6.8113	7.7202	5.7265	0.401
TTC-709	CTRP2	6.9397	11.9492	3.8008	7.8229
TE 617.T	CTRP2	7.0922	9.6421	5.0258	2.6312
G-401	CTRP2	7.2875	10.4503	4.7713	3.3738
Rh41	CTRP2	7.3417	10.3918	4.8333	3.0637
SW982	CTRP2	7.5391	8.7835	5.632	0.2603
G-402	CTRP2	7.6257	10.8042	4.8175	2.7858
BT-16	CTRP2	7.6295	8.9207	5.6176	0.2553
A-204	CTRP2	7.6375	10.3068	5.0488	1.9311
KYM-1	CTRP2	7.757	9.9422	5.2699	1.0895
GCT	CTRP2	7.8166	13.1517	3.8371	6.3472
RD	CTRP2	7.9199	9.9139	5.3597	0.7207
MES-SA	CTRP2	7.9847	9.1218	5.6796	0.0802
HT-1080	CTRP2	8.071	9.503	5.5783	0.1895
SK-UT-1	CTRP2	8.1752	9.7284	5.5373	0.2256
SK-LMS-1	CTRP2	8.1997	9.7337	5.5447	0.2075
Tm87-16	CTRP2	8.2597	10.085	5.4402	0.3717
Hs 729.T	CTRP2	8.8937	10.2454	5.615	0.0397
Rh18	CTRP2	10.6978	22.0439	1.5105	10.9697

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	7.7937	9.5824	5.434	0.5982

Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	8.5986	15.4684	3.2532	7.5456
TOV-21G	GDSC1; GDSC2	0.7434	7.0574	-0.97	30.3498
OV56	GDSC1; GDSC2	1.4003	3.4461	1.1896	18.0112
TYK-nu	GDSC1; GDSC2	1.8443	4.7169	1.1928	16.3273
OAW42	GDSC1; GDSC2	1.9478	5.8004	0.8101	17.9638
OVTOKO	GDSC1; GDSC2	2.13	5.6583	1.0559	16.0732
A2780	GDSC1; GDSC2	2.2104	4.8108	1.5267	13.3058
OC 314	GDSC1; GDSC2	2.3375	4.4341	1.824	11.2989
OVCAR-5	GDSC1; GDSC2	2.4571	5.7952	1.307	13.6851
TOV-112D	GDSC1; GDSC2	2.6206	4.8524	1.9152	9.8704
ES-2	GDSC1; GDSC2	2.7607	5.4374	1.7665	10.2499
IGROV-1	GDSC1; GDSC2	2.7888	5.7117	1.6581	10.7621
OAW28	GDSC1; GDSC2	2.8081	6.5363	1.2687	12.8418
DOV13	GDSC1; GDSC2	2.9715	4.4883	2.426	5.9869
JHOS-4	GDSC1	3.0521	5.4304	2.0352	9.1753
OVK18	GDSC1	3.0647	9.5215	0.0053	21.093
OVISE	GDSC1; GDSC2	3.1096	5.9363	1.8339	8.8775
EFO-27	GDSC1	3.3047	5.4106	2.2632	6.9116
SK-OV-3	GDSC1; GDSC2	3.6369	5.119	2.6704	2.9087
OVCAR-3	GDSC1; GDSC2	3.6376	7.2806	1.5991	8.8368
OVCAR-8	GDSC1; GDSC2	3.8211	8.3767	1.1975	10.5922
FU-OV-1	GDSC1; GDSC2	4.0052	6.1622	2.423	3.5183
Kuramochi	GDSC1; GDSC2	4.1585	8.002	1.6372	7.46
JHOS-2	GDSC1	4.2953	8.943	1.2755	10.4931
OVKATE	GDSC1; GDSC2	4.547	6.8144	2.4601	2.4345
OVCAR-4	GDSC1; GDSC2	5.0259	11.2442	0.6753	10.6979
OV-90	GDSC1; GDSC2	5.0841	9.7641	1.4245	6.8032
EFO-21	GDSC1; GDSC2	5.4229	7.1384	2.7547	0.4539
Caov-4	GDSC1; GDSC2	5.5038	13.6641	-0.163	13.6777
A2780	CTRP2	5.6073	7.5598	4.8974	5.7369
RMG-I	GDSC1; GDSC2	5.8391	7.8562	2.6565	0.508
OVK18	CTRP2	6.721	9.4729	4.8561	3.8303
OV7	CTRP2	6.9457	9.5893	4.9551	3.1034
OVSAHO	CTRP2	7.2735	11.2369	4.3873	4.9183
FU-OV-1	CTRP2	7.3861	19.9374	-0.552	18.4899
OV56	CTRP2	7.3997	8.6224	5.6348	0.3112
OAW42	CTRP2	7.4439	9.0377	5.4907	0.6555
JHOM-1	CTRP2	7.4539	8.8957	5.5524	0.4825
IGROV-1	CTRP2	7.5327	10.2644	5.0078	2.1862
HEY A8	CTRP2	7.5481	8.9481	5.5734	0.383
TOV-21G	CTRP2	7.5847	8.8209	5.6365	0.235
SNU-119	CTRP2	7.6395	9.6893	5.317	1.0335
COV434	CTRP2	7.8524	10.1265	5.2405	1.108
JHOC-5	CTRP2	7.8891	9.5029	5.5061	0.3817
TYK-nu	CTRP2	7.9096	9.6619	5.4541	0.4892
JHOS-2	CTRP2	7.9208	9.485	5.5259	0.3282
RMG-I	CTRP2	7.9332	10.3414	5.191	1.1991
OC 314	CTRP2	7.9537	9.1974	5.6424	0.1271
OVCAR-5	CTRP2	7.9641	9.7344	5.4496	0.4739
OVCAR-4	CTRP2	7.9723	10.6482	5.0812	1.5154
DOV13	CTRP2	7.9744	9.5098	5.5383	0.2851
COV644	CTRP2	8.0371	9.4345	5.5898	0.1807
SNU-8	CTRP2	8.0535	14.305	3.4447	7.5562
COV362	CTRP2	8.1005	10.6478	5.1464	1.2108
OAW28	CTRP2	8.1966	10.5126	5.2475	0.857
MCAS	CTRP2	8.2094	10.0645	5.4273	0.4172
OVCAR-8	CTRP2	8.2129	9.7579	5.5411	0.2097
TOV-112D	CTRP2	8.3015	10.2778	5.3851	0.4684
EFO-21	CTRP2	8.3033	9.7801	5.567	0.1528
Caov-3	CTRP2	8.3296	9.9361	5.5217	0.2094
Kuramochi	CTRP2	8.4358	10.2249	5.4587	0.2803
ES2	CTRP2	8.48	18.9227	1.5049	14.0663
SK-OV-3	CTRP2	8.5512	10.2163	5.5054	0.1814
OVTOKO	CTRP2	8.6462	10.4618	5.4541	0.2313
OV-90	CTRP2	8.6844	10.0532	5.6081	0.0595
EFO-27	CTRP2	8.7208	10.4099	5.4998	0.1552
SNU-840	CTRP2	8.9885	10.6786	5.5029	0.1103
ONCO-DG-1	CTRP2	12.6698	27.4863	0.2133	12.5057
OVISE	CTRP2	14.269	32.3813	-1.0641	14.0531

Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H28	GDSC1; GDSC2	3.3162	4.4415	2.7574	3.1706
MPP 89	GDSC1; GDSC2	3.5612	9.2894	0.5352	14.6981
MSTO-211H	GDSC1; GDSC2	3.7468	6.6092	2.0176	6.2694
NCI-H2052	GDSC1; GDSC2	4.3804	9.5409	1.0444	10.1501
IST-Mes1	GDSC1; GDSC2	4.4255	8.7296	1.4735	7.7894
NCI-H2452	GDSC1; GDSC2	4.4688	6.9171	2.3665	3.0154
NCI-H2452	CTRP2	7.3589	16.0042	2.113	13.7447
NCI-H2052	CTRP2	7.3797	9.2336	4.4335	0.3668
ACC-MESO-1	CTRP2	7.5771	9.1154	5.521	0.4951
IST-Mes1	CTRP2	8.0006	11.7205	4.6234	3.0872
JL-1	CTRP2	8.1778	9.3869	5.6573	0.0751
MPP 89	CTRP2	8.2109	9.7007	5.5606	0.1814
NCI-H28	CTRP2	8.5903	10.1868	5.5299	0.1435

Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
DU145	GDSC1; GDSC2	3.0914	5.3313	2.1192	7.339
PC-3	GDSC1; GDSC2	3.3806	5.3637	2.3495	5.2868
22Rv1	GDSC1; GDSC2	3.9468	7.7978	1.581	8.2232
LNCaP clone FGC	GDSC1; GDSC2	5.3276	9.2238	1.8275	4.3852
VCaP	GDSC1; GDSC2	5.5286	7.6022	2.6233	0.7701
VCaP	CTRP2	7.9907	9.6633	5.4878	0.3788
PaCa-3	CTRP2	8.0613	9.0304	5.7364	0.0302
LNCaP clone FGC	CTRP2	8.6787	10.4299	5.4775	0.1913
22Rv1	CTRP2	8.8681	10.8316	5.4062	0.2474
DU145	CTRP2	8.9106	10.8534	5.4144	0.2259

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
A-253	GDSC1; GDSC2	2.298	4.1494	1.9055	11.0115
YD-15	CTRP2	7.4645	8.4965	5.7075	0.1486
A-253	CTRP2	8.6658	10.354	5.4993	0.1661

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1	3.1931	4.9794	2.3835	6.475

Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NUGC-3	GDSC1; GDSC2	-0.3312	3.1003	-0.6066	33.5356
SNU-5	GDSC1; GDSC2	1.9012	3.9694	1.5566	14.2528
HGC-27	GDSC1; GDSC2	2.8027	4.8599	2.0866	8.3644
MKN45	GDSC1; GDSC2	3.0214	5.144	2.1498	7.3666
SK-GT-2	GDSC1; GDSC2	3.0526	5.8095	1.8471	8.9607
RERF-GC-1B	GDSC1; GDSC2	3.154	4.7694	2.4539	5.3009
SNU-1	GDSC1; GDSC2	3.2649	6.1237	1.8733	8.2431
TMK-1	GDSC1	3.2713	9.7854	0.0479	20.2268
AGS	GDSC1; GDSC2	3.3936	7.6335	1.2256	11.4884
RF-48	GDSC1; GDSC2	3.4905	5.5996	2.3203	5.1808
SCH	GDSC1	3.4965	6.6668	1.7927	9.3866
GCIY	GDSC1; GDSC2	3.5845	5.9761	2.2069	5.5906
HSC-39	GDSC1; GDSC2	3.6814	5.5428	2.4949	3.778
TGBC11TKB	GDSC1; GDSC2	3.7289	5.279	2.6583	2.7864
SNU-16	GDSC1; GDSC2	3.7918	8.3992	1.1635	10.8442
MKN7	GDSC1; GDSC2	3.8195	6.4694	2.1412	5.7233
KATO III	GDSC1; GDSC2	3.9833	5.8622	2.5517	2.8745
MKN1	GDSC1; GDSC2	3.9978	8.7138	1.1665	10.3494
NUGC-4	GDSC1; GDSC2	4.1883	7.042	2.125	4.7658
ECC10	GDSC1; GDSC2	4.1952	7.2356	2.0364	5.2277
NCI-N87	GDSC1; GDSC2	4.5628	10.1791	0.8644	10.6932
MKN28	GDSC1; GDSC2	4.5794	8.1543	1.8563	5.4651
Hs 746.T	GDSC1; GDSC2	4.6302	10.4039	0.8032	10.8635
Fu97	GDSC1; GDSC2	4.6392	9.3067	1.3435	8.0511
IM95	GDSC1; GDSC2	5.0207	6.8856	2.6781	0.9532
23132/87	GDSC1; GDSC2	5.5234	10.13	1.5307	5.5434
OCUM-1	GDSC1; GDSC2	5.9798	12.5734	0.6793	8.9267
GSU	CTRP2	6.5624	7.6427	5.6246	0.9798
ECC10	CTRP2	6.7184	12.287	2.7054	7.4963
Fu97	CTRP2	7.2163	8.8406	4.5127	0.2724
Hs 746.T	CTRP2	7.6515	10.0577	5.1659	1.5133
MKN7	CTRP2	7.7154	9.4373	5.4561	0.585
ECC12	CTRP2	7.7895	8.9995	5.6512	0.1511
MKN1	CTRP2	7.7943	9.3146	5.5377	0.3537
SNU-5	CTRP2	7.803	9.1543	5.6007	0.2283
HuG1-N	CTRP2	7.8161	11.249	4.7283	2.9035
SNU-16	CTRP2	7.8427	9.0279	5.661	0.1259
NUGC-4	CTRP2	7.8597	9.8091	5.3739	0.7185
HGC-27	CTRP2	7.8624	10.5711	5.0563	1.6925
NCI-N87	CTRP2	7.9129	10.2102	5.2356	1.0785
SNU-620	CTRP2	7.9707	9.0006	5.7157	0.0508
23132/87	CTRP2	8.0052	9.5142	5.5489	0.256
SNU-668	CTRP2	8.0295	9.3295	5.6241	0.1352
GSS	CTRP2	8.0538	9.6999	5.4999	0.3303
SNU-1	CTRP2	8.0742	9.847	5.4532	0.4177
NUGC-3	CTRP2	8.0834	9.7676	5.4867	0.3452
IM95	CTRP2	8.1477	9.9401	5.4486	0.3976
LMSU	CTRP2	8.1812	11.0828	5.0042	1.5914
SNU-601	CTRP2	8.1872	9.6181	5.581	0.1586
AGS	CTRP2	8.2643	17.6486	1.9722	12.779
SH-10-TC	CTRP2	8.2816	9.3041	5.72	0.0252
KATO III	CTRP2	8.309	10.2219	5.4093	0.415
SNU-216	CTRP2	8.5359	10.6916	5.3264	0.4964
NCC-StC-K140	CTRP2	8.73	11.3307	5.1643	0.776
MKN74	CTRP2	8.8953	11.0241	5.3476	0.3317
SNU-719	CTRP2	8.9066	10.5842	5.5062	0.1184
KE-39	CTRP2	9.9528	12.2859	5.2951	0.1761
MKN45	CTRP2	12.6172	30.4833	-1.2272	16.2807
SNG-M	GDSC1; GDSC2	4.4037	6.652	2.4488	2.7034
SNG-M	CTRP2	7.6386	13.5832	3.5067	7.9156
SNU-685	CTRP2	8.1946	9.3311	5.6818	0.0535
SNU-1077	CTRP2	8.4496	9.8373	5.5996	0.0924

Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IHH-4	GDSC1; GDSC2	1.7	4.2213	1.245	16.582
CGTH-W-1	GDSC1; GDSC2	1.7711	4.3373	1.2743	16.1706
BHT-101	GDSC1; GDSC2	2.1358	5.1949	1.2769	14.8829
FTC-133	GDSC1; GDSC2	2.1755	6.0005	0.9385	16.5452
K5	GDSC1; GDSC2	2.5166	4.4921	1.9799	9.8624
HTC-C3	GDSC1; GDSC2	3.055	4.8121	2.3441	6.1919
ML-1 [Human leukemia]	GDSC1	3.0597	11.3365	-0.9059	25.1781
KMH-2	GDSC1	3.1645	5.3728	2.1626	7.9936
CAL-62	GDSC1; GDSC2	3.2387	5.148	2.3386	5.7141
ASH-3	GDSC1; GDSC2	3.3735	6.2375	1.907	7.7762
WRO	GDSC1; GDSC2	3.3836	4.3509	2.8579	2.4399
8505C	GDSC1; GDSC2	3.7088	6.7563	1.9155	6.9203
TT2609-C02	GDSC1; GDSC2	3.8548	6.8799	1.9652	6.3191
TT	GDSC1; GDSC2	4.1097	6.7023	2.2347	4.3277
8305C	GDSC1; GDSC2	4.439	6.9554	2.3303	3.2461
B-CPAP	GDSC1; GDSC2	5.3281	7.2426	2.6754	0.736
CGTH-W-1	CTRP2	7.8233	9.3925	5.5204	0.3787
SW579	CTRP2	7.9685	8.9888	5.7189	0.0487
TT	CTRP2	8.0453	9.6748	5.5058	0.322
B-CPAP	CTRP2	8.0541	9.3379	5.6301	0.1229
BHT-101	CTRP2	8.1498	9.8217	5.4934	0.309
CAL-62	CTRP2	8.1978	9.6282	5.5813	0.1559
FTC-133	CTRP2	8.26	9.5835	5.6193	0.1001
FTC-238	CTRP2	8.3158	9.3905	5.703	0.0312
8305C	CTRP2	8.3664	12.7467	4.3736	3.6043
TT2609-C02	CTRP2	8.5935	10.7244	5.3378	0.4504
ML-1 [Human leukemia]	CTRP2	10.4153	40.3157	-7.5989	29.8922
8505C	CTRP2	12.7595	24.416	1.6674	8.1969

Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HSC-4	GDSC1; GDSC2	0.8583	2.6724	0.7787	22.1885
PCI-06A	GDSC1	0.9023	4.2472	0.3813	27.6254
KOSC-2	GDSC1	1.2388	5.3465	0.2954	26.5257
JHU-029	GDSC1	1.2893	5.5444	0.2615	26.4768
PCI-04B	GDSC1	1.5495	4.5471	0.9556	21.5416
SKN-3	GDSC1; GDSC2	1.857	4.1078	1.4564	14.9256
JHU-011	GDSC1	1.8892	6.7862	0.2876	23.8407
HSC-3	GDSC1; GDSC2	2.0351	4.4756	1.4938	14.0869
SAS	GDSC1; GDSC2	2.0492	4.8742	1.3346	14.8713
HSC-2	GDSC1; GDSC2	2.0593	6.527	0.5752	18.8056
CAL-27	GDSC1; GDSC2	2.5652	4.8233	1.8748	10.2666
BICR 22	GDSC1; GDSC2	2.5766	4.8339	1.881	10.1967
FaDu	GDSC1; GDSC2	2.6199	4.8019	1.9384	9.7469
PCI-38	GDSC1	2.8764	5.042	2.0672	9.5598
BB30-HNC	GDSC1	2.9095	7.2636	0.9976	16.1516
Ca9-22	GDSC1; GDSC2	2.9445	5.9739	1.6696	10.2487
BHY	GDSC1	2.9944	4.5136	2.4351	6.8013
CAL-33	GDSC1; GDSC2	3.0548	5.9931	1.7577	9.4515
HO-1-N-1	GDSC1; GDSC2	3.0722	4.3797	2.5729	4.8756
KON	GDSC1	3.1118	9.0226	0.2946	19.4614
BICR 78	GDSC1; GDSC2	3.1131	6.9056	1.3533	11.5277
PCI-30	GDSC1; GDSC2	3.1935	6.6173	1.566	10.1395
DOK	GDSC1; GDSC2	3.2533	6.0706	1.89	8.1805
UPCI-SCC-090	GDSC1; GDSC2	3.3353	4.7145	2.6368	3.7956
NCI-H3118	GDSC1; GDSC2	3.3565	7.9806	1.0213	12.6861
HO-1-u-1	GDSC1; GDSC2	3.4269	4.5467	2.7947	2.6885
SAT [Human HNSCC]	GDSC1; GDSC2	3.4325	8.8452	0.6519	14.4314
SCC-15	GDSC1; GDSC2	3.4926	7.1073	1.5695	9.3526
SCC-9	GDSC1; GDSC2	3.5349	5.3259	2.4915	4.1234
BICR 10	GDSC1; GDSC2	3.5866	6.851	1.7728	7.998
JHU-022	GDSC1; GDSC2	3.6205	8.1261	1.1639	11.2544
SCC-4	GDSC1; GDSC2	3.8018	7.2505	1.7419	7.667
Detroit 562	GDSC1; GDSC2	3.8371	5.9632	2.4021	3.9604
SCC-25	GDSC1	4.0147	6.782	2.1298	5.888
LB771-HNC	GDSC1; GDSC2	4.2047	8.3543	1.4982	8.1134
BB49-HNC	GDSC1; GDSC2	4.5832	9.6756	1.125	9.3052
OSC-20	GDSC1; GDSC2	4.6645	8.3216	1.8329	5.4348
PCI-15A	GDSC1	5.4476	6.8974	2.8515	0.2651
OSC-19	GDSC1	5.8789	7.7211	2.7212	0.3985
YD-8	CTRP2	6.9089	10.4726	3.6817	3.185
SNU-1214	CTRP2	7.2703	10.4625	4.7544	3.4623
Detroit 562	CTRP2	7.3189	9.3104	5.3113	1.3238
PE/CA-PJ15	GDSC1	7.3706	16.717	-0.3773	12.5849
YD-10B	CTRP2	7.5371	9.0686	5.5215	0.5158
HSC-4	CTRP2	7.5665	8.9966	5.5626	0.3994
CAL-27	CTRP2	7.8303	9.1175	5.6246	0.1809
BICR 22	CTRP2	7.8443	9.1144	5.631	0.1674
SNU-1066	CTRP2	7.8536	9.8506	5.3543	0.7754
HSC-2	CTRP2	7.8783	9.3306	5.5659	0.2665
HSC-3	CTRP2	8.0086	9.3271	5.6172	0.1486
FaDu	CTRP2	8.0092	9.4719	5.5658	0.2259
BICR 56	CTRP2	8.0231	9.371	5.6071	0.1593
PE/CA-PJ41 (clone D2)	CTRP2	8.0393	10.8409	5.0337	1.6136
BICR 31	CTRP2	8.0517	11.2745	4.8521	2.2152
PE/CA-PJ34 (clone C12)	CTRP2	8.0525	9.3967	5.6089	0.1502
SCC-4	CTRP2	8.0778	10.4467	5.2183	1.0142
SNU-1076	CTRP2	8.1117	9.5928	5.5616	0.2044
SCC-25	CTRP2	8.116	10.0183	5.4056	0.5043
BICR 6	CTRP2	8.152	9.3018	5.677	0.0616
SNU-899	CTRP2	8.1602	9.625	5.5685	0.182
BICR 18	CTRP2	8.1637	9.9373	5.4562	0.3759
PE/CA-PJ49	CTRP2	8.2274	9.5466	5.6204	0.1041
CAL-33	CTRP2	8.2904	10.0973	5.448	0.3458
PE/CA-PJ15	CTRP2	8.3286	10.1419	5.4469	0.3348
SCC-9	CTRP2	8.5815	10.2397	5.5083	0.1714
SNU-46	CTRP2	8.5837	10.0025	5.5905	0.0835
BHY	CTRP2	8.6563	10.5236	5.4359	0.2561
SNU-1041	CTRP2	8.7317	10.1426	5.5944	0.0646
BICR 16	CTRP2	12.2227	25.9858	0.6316	11.8333

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
639V	GDSC1; GDSC2	1.0737	2.7592	0.9959	20.2725
BFTC-905	GDSC1; GDSC2	1.3528	3.7079	1.0565	18.8475
647V	GDSC1; GDSC2	1.4924	3.4291	1.2951	17.1321
T24	GDSC1	2.1472	6.1096	0.8591	19.6759
J82	GDSC1; GDSC2	2.2815	4.8461	1.5825	12.7698
5637	GDSC1; GDSC2	2.4203	5.1582	1.5754	12.3512
UM-UC-3	GDSC1; GDSC2	2.589	4.0682	2.2424	8.2244
TCCSUP	GDSC1; GDSC2	2.7754	5.4177	1.7898	10.0776
CAL-29	GDSC1; GDSC2	2.9013	4.3758	2.4136	6.2713
KU-19-19	GDSC1; GDSC2	3.0988	5.6796	1.9523	8.2478
RT-112	GDSC1; GDSC2	3.3588	4.5087	2.759	3.0531
SW780	GDSC1; GDSC2	3.5496	6.4938	1.9215	7.2608
HT-1376	GDSC1; GDSC2	3.5727	5.1524	2.6064	3.4005
SW1710	GDSC1; GDSC2	3.8581	5.7873	2.5024	3.3742
RT-4	GDSC1; GDSC2	4.6382	12.918	-0.4282	16.66
HT-1197	GDSC1; GDSC2	4.7167	9.4594	1.3234	8.0047
253J	CTRP2	6.1605	7.3651	5.4781	2.1654
BFTC-905	CTRP2	7.4913	9.0194	5.5202	0.5452
RT-4	CTRP2	7.494	10.8995	4.6923	3.4185
HT-1197	CTRP2	7.6554	9.3062	5.4808	0.5546
BC-3C	CTRP2	7.7187	9.741	5.3347	0.9215
TCCSUP	CTRP2	7.7456	9.3882	5.4887	0.4872
RT-112	CTRP2	7.7843	9.066	5.6255	0.1921
HT-1376	CTRP2	7.8084	10.7049	4.9682	2.0461
SCaBER	CTRP2	7.8876	9.596	5.47	0.4627
639V	CTRP2	7.9507	9.4625	5.5462	0.2785
VM-CUB-1	CTRP2	7.9509	10.2583	5.2343	1.0551
JMSU-1	CTRP2	8.1816	9.8244	5.505	0.2778
253J-BV	CTRP2	8.2067	9.6428	5.5795	0.1564
J82	CTRP2	8.2116	9.9698	5.4635	0.3439
KMBC-2	CTRP2	8.2522	10.8767	5.126	1.1637
647V	CTRP2	8.2727	9.5335	5.6408	0.0779
U-BLC1	CTRP2	8.2815	10.6582	5.2283	0.8578
SW1710	CTRP2	8.291	10.9274	5.1238	1.1434
UM-UC-3	CTRP2	8.4456	10.3285	5.4248	0.3363
CAL-29	CTRP2	8.542	9.8952	5.6122	0.0705
UM-UC-1	CTRP2	8.8117	10.8919	5.363	0.3304
5637	CTRP2	8.9842	10.6094	5.5248	0.0917
T24	CTRP2	9.756	16.4839	3.4973	5.2686
KU-19-19	CTRP2	12.545	30.1563	-1.1196	16.1061

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NT2-D1	GDSC1; GDSC2	-0.1913	3.5205	-0.5681	32.7392
PA-1	GDSC1; GDSC2	0.8095	3.3373	0.5758	23.3424
SiSo	GDSC1; GDSC2	1.2625	3.5984	0.9933	19.5123
NEC8	GDSC1; GDSC2	1.5925	3.9386	1.2364	17.0295
JAR	GDSC1	2.1744	4.5516	1.6051	15.0847
ME-180	GDSC1; GDSC2	2.3092	4.454	1.7862	11.5958
TC-YIK	GDSC1; GDSC2	2.4452	5.5548	1.4112	13.1587
C-33 A	GDSC1; GDSC2	2.637	4.7033	2.0016	9.3498
Ca Ski	GDSC1; GDSC2	2.6925	5.1109	1.8608	9.9405
JEG-3	GDSC1	2.7302	9.2029	-0.1251	22.834
PWR-1E	GDSC1; GDSC2	2.8175	5.7854	1.6481	10.7333
HT-3	GDSC1; GDSC2	2.8838	4.8501	2.1678	7.6719
KGN	GDSC1; GDSC2	2.9971	6.1657	1.621	10.3698
NCC-IT	GDSC2	3.0381	4.8583	1.8002	3.5853
SW756	GDSC1; GDSC2	3.1188	4.5605	2.5262	4.9988
BPH-1	GDSC1; GDSC2	3.1264	6.6239	1.5053	10.655
SKN	GDSC1; GDSC2	3.1824	6.0484	1.8407	8.6431
MS751	GDSC1; GDSC2	3.1924	4.5418	2.6009	4.3757
SW954	GDSC1	3.1925	6.3748	1.6864	10.97
CAL-39	GDSC1; GDSC2	3.2741	5.2295	2.328	5.6801
ACC-OV7	GDSC1	3.2744	6.1436	1.8713	9.5337
C-4-I	GDSC1; GDSC2	3.3093	5.1764	2.3841	5.2749
HEC-1	GDSC1; GDSC2	3.3166	4.9175	2.5197	4.4981
OMC-1 [Human cervical carcinoma]	GDSC1	3.3464	5.5193	2.2435	6.9146
HEY	GDSC1; GDSC2	3.5075	5.3186	2.4737	4.2862
PEO1	GDSC1; GDSC2	3.5326	7.4026	1.4544	9.8884
SKG-IIIa	GDSC1; GDSC2	3.5397	6.5365	1.8923	7.4471
SiHa	GDSC1; GDSC2	3.5527	5.0332	2.6502	3.203
JHOS-3	GDSC1	3.8306	6.6027	2.0838	6.6265
SW962	GDSC1	3.8804	7.0584	1.8963	7.6914
DoTc2 4510	GDSC1; GDSC2	3.9718	7.4569	1.7679	7.1468
DSH1	GDSC1; GDSC2	4.1322	6.4726	2.3599	3.6185
OVCA420	GDSC1; GDSC2	4.2049	6.5524	2.37	3.4357
LB831-BLC	GDSC1; GDSC2	4.2682	7.878	1.7762	6.4842
OVCA433	GDSC1	4.4215	8.487	1.5885	8.2978
OV17R	GDSC1	4.5845	9.6359	1.1453	10.5651
UWB1.289	GDSC1	4.7802	9.8819	1.1634	10.0063
HeLa	GDSC1; GDSC2	4.9898	11.8796	0.3409	12.3967
OVMIU	GDSC1; GDSC2	5.1523	8.2211	2.1772	2.9534
HeLa	CTRP2	7.3185	8.2685	5.7335	0.1474

Drug-Drug Interaction (DDI) Information of This Drug

Coadministration of a Drug Treating the Disease Different from Cisplatin (Comorbidity)

DDI Drug Name	DDI Drug ID	Severity	Mechanism	Comorbidity	REF
Remdesivir	DMBFZ6L	Moderate	Decreased renal excretion of Cisplatin caused by Remdesivir mediated nephrotoxicity.	1D6YCoronavirus Disease 2019 [1D6YCoronavirus Disease 2019]	[32]
Inotersen	DMJ93CT	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Inotersen.	Amyloidosis [5D00]	[33]
Dronedarone	DMA8FS5	Major	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Dronedarone.	Angina pectoris [BA40]	[34]
Roflumilast	DMPGHY8	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Roflumilast.	Asthma [CA23]	[33]
Ofloxacin	DM0VQN3	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Ofloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Ciprofloxacin XR	DM2NLS9	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Ciprofloxacin XR.	Bacterial infection [1A00-1C4Z]	[35]
Trovafloxacin	DM6AN32	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Trovafloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Sparfloxacin	DMB4HCT	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Sparfloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Gemifloxacin	DMHT34O	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Gemifloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Norfloxacin	DMIZ6W2	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Norfloxacin.	Bacterial infection [1A00-1C4Z]	[35]
ABT-492	DMJFD2I	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by ABT-492.	Bacterial infection [1A00-1C4Z]	[35]
Rabeprazole	DMMZXIW	Moderate	Increased risk of hypomagnesemia by the combination of Cisplatin and Rabeprazole.	Bacterial infection [1A00-1C4Z]	[36]
Levofloxacin	DMS60RB	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Levofloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Lomefloxacin	DMVRH9C	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Lomefloxacin.	Bacterial infection [1A00-1C4Z]	[35]
Etidronic acid	DM1XHYJ	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Etidronic acid.	Bone paget disease [FB85]	[37]
Iodipamide	DMXIQYS	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Iodipamide.	Cholelithiasis [DC11]	[38]
Methoxyflurane	DML0RAE	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Methoxyflurane.	Corneal disease [9A76-9A78]	[33]
Ethacrynic acid	DM60QMR	Moderate	Increased risk of ototoxicity by the combination of Cisplatin and Ethacrynic acid.	Essential hypertension [BA00]	[39]
Amphotericin B	DMTAJQE	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Amphotericin B.	Fungal infection [1F29-1F2F]	[32]
Dexlansoprazole	DM1DBV5	Moderate	Increased risk of hypomagnesemia by the combination of Cisplatin and Dexlansoprazole.	Gastro-oesophageal reflux disease [DA22]	[36]
Furosemide	DMMQ8ZG	Moderate	Increased risk of ototoxicity by the combination of Cisplatin and Furosemide.	Heart failure [BD10-BD1Z]	[40]
Bumetanide	DMRV7H0	Moderate	Increased risk of ototoxicity by the combination of Cisplatin and Bumetanide.	Heart failure [BD10-BD1Z]	[40]
Brentuximab vedotin	DMWLC57	Moderate	Increased risk of peripheral neuropathy by the combination of Cisplatin and Brentuximab vedotin.	Hodgkin lymphoma [2B30]	[41]
Zalcitabine	DMH7MUV	Moderate	Increased risk of peripheral neuropathy by the combination of Cisplatin and Zalcitabine.	Human immunodeficiency virus disease [1C60-1C62]	[42]
Teriflunomide	DMQ2FKJ	Major	Additive immunosuppressive effects by the combination of Cisplatin and Teriflunomide.	Hyper-lipoproteinaemia [5C80]	[43]
Etelcalcetide	DMHP9BL	Major	Increased risk of hypocalcemia by the combination of Cisplatin and Etelcalcetide.	Hyper-parathyroidism [5A51]	[33]
Diazoxide	DML1538	Minor	Increased risk of nephrotoxicity by the combination of Cisplatin and Diazoxide.	Hypertension [BA00-BA04]	[44]
Givosiran	DM5PFIJ	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Givosiran.	Inborn porphyrin/heme metabolism error [5C58]	[32]
Balsalazide	DM7I1T9	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Balsalazide.	Indeterminate colitis [DD72]	[45]
Methotrexate	DM2TEOL	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Methotrexate.	Leukaemia [2A60-2B33]	[32]
Ibandronate	DM0QZBN	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Ibandronate.	Low bone mass disorder [FB83]	[46]
Denosumab	DMNI0KO	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Denosumab.	Low bone mass disorder [FB83]	[47]
Arsenic trioxide	DM61TA4	Major	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Arsenic trioxide.	Mature B-cell lymphoma [2A85]	[48]
Clofarabine	DMCVJ86	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Clofarabine.	Mature B-cell lymphoma [2A85]	[49]
Exjade	DMHPRWG	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Exjade.	Mineral absorption/transport disorder [5C64]	[50]
Thalidomide	DM70BU5	Major	Additive thrombogenic effects by the combination of Cisplatin and Thalidomide.	Multiple myeloma [2A83]	[51]
Tecfidera	DM2OVDT	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Tecfidera.	Multiple sclerosis [8A40]	[52]
Siponimod	DM2R86O	Major	Additive immunosuppressive effects by the combination of Cisplatin and Siponimod.	Multiple sclerosis [8A40]	[32]
Fingolimod	DM5JVAN	Major	Additive immunosuppressive effects by the combination of Cisplatin and Fingolimod.	Multiple sclerosis [8A40]	[53]
Ocrelizumab	DMEZ2KH	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Ocrelizumab.	Multiple sclerosis [8A40]	[54]
Ozanimod	DMT6AM2	Major	Additive immunosuppressive effects by the combination of Cisplatin and Ozanimod.	Multiple sclerosis [8A40]	[33]
Omacetaxine mepesuccinate	DMPU2WX	Moderate	Additive myelosuppressive effects by the combination of Cisplatin and Omacetaxine mepesuccinate.	Myeloproliferative neoplasm [2A20]	[55]
Levomethadyl Acetate	DM06HG5	Major	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Levomethadyl Acetate.	Opioid use disorder [6C43]	[56]
Esomeprazole	DM7BN0X	Moderate	Increased risk of hypomagnesemia by the combination of Cisplatin and Esomeprazole.	Peptic ulcer [DA61]	[36]
Pemetrexed	DMMX2E6	Moderate	Decreased renal excretion of Cisplatin caused by Pemetrexed mediated nephrotoxicity.	Pleural mesothelioma [2C26]	[57]
Fluphenazine	DMIT8LX	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Fluphenazine.	Psychotic disorder [6A20-6A25]	[32]
Everolimus	DM8X2EH	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Everolimus.	Renal cell carcinoma [2C90]	[58]
Temsirolimus	DMS104F	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Temsirolimus.	Renal cell carcinoma [2C90]	[58]
Gatifloxacin	DMSL679	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Gatifloxacin.	Respiratory infection [CA07-CA4Z]	[35]
Canakinumab	DM8HLO5	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Canakinumab.	Rheumatoid arthritis [FA20]	[59]
Rilonacept	DMGLUQS	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Rilonacept.	Rheumatoid arthritis [FA20]	[59]
Golimumab	DMHZV7X	Major	Additive immunosuppressive effects by the combination of Cisplatin and Golimumab.	Rheumatoid arthritis [FA20]	[60]
Sulfasalazine	DMICA9H	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Sulfasalazine.	Rheumatoid arthritis [FA20]	[45]
Leflunomide	DMR8ONJ	Major	Additive myelosuppressive effects by the combination of Cisplatin and Leflunomide.	Rheumatoid arthritis [FA20]	[43]
Thioridazine	DM35M8J	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Thioridazine.	Schizophrenia [6A20]	[32]
Paliperidone	DM7NPJS	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Paliperidone.	Schizophrenia [6A20]	[32]
Trifluoperazine	DMKBYWI	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Trifluoperazine.	Schizophrenia [6A20]	[32]
Risperidone	DMN6DXL	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Risperidone.	Schizophrenia [6A20]	[32]
Amisulpride	DMSJVAM	Moderate	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Amisulpride.	Schizophrenia [6A20]	[32]
Pimozide	DMW83TP	Major	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Pimozide.	Schizophrenia [6A20]	[61]
Anthrax vaccine	DM9GSWY	Moderate	Antagonize the effect of Cisplatin when combined with Anthrax vaccine.	Sepsis [1G40-1G41]	[62]
Sirolimus	DMGW1ID	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Sirolimus.	Transplant rejection [NE84]	[58]
Azathioprine	DMMZSXQ	Moderate	Additive immunosuppressive effects by the combination of Cisplatin and Azathioprine.	Transplant rejection [NE84]	[32]
Tacrolimus	DMZ7XNQ	Major	Increased risk of nephrotoxicity by the combination of Cisplatin and Tacrolimus.	Transplant rejection [NE84]	[58]
Olsalazine	DMZW9HA	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Olsalazine.	Ulcerative colitis [DD71]	[45]
Cinoxacin	DM4EWNS	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Cinoxacin.	Urinary tract infection [GC08]	[35]
Nalidixic acid	DMRM0JV	Minor	Decreased absorption of Cisplatin due to intestinal mucosa variation caused by Nalidixic acid.	Urinary tract infection [GC08]	[35]
Amiodarone	DMUTEX3	Major	Increased risk of ventricular arrhythmias by the combination of Cisplatin and Amiodarone.	Ventricular tachyarrhythmia [BC71]	[63]
Ganciclovir	DM1MBYQ	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Ganciclovir.	Virus infection [1A24-1D9Z]	[32]
Valaciclovir	DMHKS94	Moderate	Increased risk of nephrotoxicity by the combination of Cisplatin and Valaciclovir.	Virus infection [1A24-1D9Z]	[33]
Valganciclovir	DMS2IUH	Moderate	Additive myelosuppressive effects by the combination of Cisplatin and Valganciclovir.	Virus infection [1A24-1D9Z]	[32]

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG

DIG Name	DIG ID	PubChem CID	Functional Classification
Mannitol	E00103	6251	Diluent; Flavoring agent; Lyophilization aid; Plasticizing agent; Tonicity agent
Sodium chloride	E00077	5234	Diluent; Tonicity agent

Pharmaceutical Formulation

Formulation Name	Drug Dosage	Dosage Form	Route
Cisplatin 10mg/vial injectable	10mg/vial	Injectable	Injection

Jump to Detail Pharmaceutical Formulation Page of This Drug

References

• [1] Cisplatin FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5343).
• [3] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [4] BDDCS applied to over 900 drugs
• [5] Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
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