Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOCQ9J)

• Drug Name: Diamide Drug Info
• Synonyms: N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide; CHEBI:48958; VLSDXINSOMDCBK-BQYQJAHWSA-N; N,N',N'-Tetramethylazodicarboxamide; AC1L1HSY; ACMC-2098cn; Lopac0_000397; MLS002153343; DTXSID6040456; CHEMBL1338900; CTK8A9086; CTK8E8363; VLSDXINSOMDCBK-UHFFFAOYSA-N; HMS2234I06; 1,1-azobis(n,n-dimethylformamide); KS-00000EC9; ANW-15093; ZINC13552228; ZINC100005746; 1,1'-azobis(N,N'-dimethylformamide); ZINC253921216; AKOS028108436; n,n,n',n'-tetramethylazo-dicarboxamide; n,n,n',n'-tetramethyl azodicarboxamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5353800
  ChEBI ID: CHEMBL48963
  CAS Number: CAS 10465-78-8
  TTD Drug ID: DMOCQ9J

Molecule-Related Drug Atlas

Drug(s) Targeting Protein tyrosine phosphatase (PTP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
INCB13739	DMLQ3PO	Type-2 diabetes	5A11	Phase 2a	[1]
KP-100	DML29RF	Type-1 diabetes	5A10	Phase 1/2	[5]
Pervanadate	DM873BS	Discovery agent	N.A.	Investigative	[1]

Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[6]
Selenium	DM25CGV	N. A.	N. A.	Approved	[7]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[8]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[9]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[10]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[11]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[12]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[13]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[14]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[15]

Drug(s) Affected By Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[16]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[17]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[18]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[19]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[20]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[21]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[22]
Dopamine	DMPGUCF	Acromegaly	5A60.0	Approved	[23]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[24]
Aminoglutethimide	DMWFHMZ	Cushing disease	5A70	Approved	[25]

Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[2]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[26]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[27]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[2]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[28]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[20]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[29]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[21]
Sodium lauryl sulfate	DMLJ634	Constipation	DD91.1	Approved	[30]
Melphalan	DMOLNHF	Hematologic disease	3C0Z	Approved	[31]

Drug(s) Affected By Riboflavin kinase (RFK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[18]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[27]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[32]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[33]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[34]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[35]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[36]
Carbamazepine	DMZOLBI	Epilepsy	8A60-8A68	Approved	[37]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[3]
Glutathione	DMAHMT9	Human immunodeficiency virus infection	1C62	Approved	[3]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein tyrosine phosphatase (PTP)	TTWC6MY	NOUNIPROTAC	Inhibitor	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF)	OTRA8ZVE	PPIF_HUMAN	Post-Translational Modifications	[2]
Riboflavin kinase (RFK)	OT77IYIS	RIFK_HUMAN	Drug Response	[3]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Gene/Protein Processing	[4]
Thioredoxin	OT6XU6VW	THIO_HUMAN	Post-Translational Modifications	[2]
Thioredoxin, mitochondrial	OTE9A5XQ	THIOM_HUMAN	Post-Translational Modifications	[2]
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3)	OTLB2WEU	PRDX3_HUMAN	Post-Translational Modifications	[2]

References

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