Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMW1LKP)

• Drug Name: Nicotinamide mononucleotide Drug Info
• Synonyms: Beta-NMN; Beta-Nicotinamide mononucleotide; Beta-Nicotinamide ribonucleotide; Nicotinamide D-ribonucleotide; Nicotinamide mononucleotide; Nicotinamide nucleotide; Nicotinamide ribonucleotide; Nicotinamide ribotide
• Therapeutic Class: Bone Density Conservation Agents
• Cross-matching ID:
  PubChem CID: 14180
  ChEBI ID: CHEBI:16171
  CAS Number: CAS 1094-61-7
  TTD Drug ID: DMW1LKP
  VARIDT Drug ID: DR00719

Molecule-Related Drug Atlas

Drug(s) Affected By Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[5]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[6]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[7]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[8]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[9]
Carbamazepine	DMZOLBI	Epilepsy	8A60-8A68	Approved	[8]
Topotecan	DMP6G8T	Central nervous system neoplasm		Approved	[10]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[5]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[11]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[12]

Drug(s) Affected By Chimeric ERCC6-PGBD3 protein (ERCC6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[13]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[14]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[15]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[16]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[17]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[16]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[18]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[19]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[20]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[21]

Drug(s) Affected By Poly polymerase 1 (PARP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[22]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[23]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[24]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[25]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[26]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[27]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[26]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[28]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[29]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[30]

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Cation-chloride cotransporter 9 (SLC12A8)	DT0OA2B	S12A8_HUMAN	Substrate	[1]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Chimeric ERCC6-PGBD3 protein (ERCC6)	OT2QZKSF	ERPG3_HUMAN	Regulation of Drug Effects	[2]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Regulation of Drug Effects	[3]
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1)	OTO3RO36	GALT1_HUMAN	Gene/Protein Processing	[4]

References

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