Details of the Drug Reposition

General Information of This Drug (ID: DMINOX3)

Drug Name
Vincristine   DMINOX3
Synonyms
LCR; Leurocristine; Marqibo; Oncovine; Tecnocris; VCR; VIN; Vincasar; Vincristina; Vincristinum; Vincrstine; Vincrystine; Vinkristin; Indole alkaloid; Liposomal Vincristine; Onco TCS; Vincristina [DCIT]; Oncovin (TN); Tecnocris (TN); Vincristine (INN); Vincristine [INN:BAN]; Vincristinum [INN-Latin]; Lilly37231 (1:1 sulfate salt); Oncovin (1:1 sulfate salt); Vincasar (1:1 sulfate salt); Vincrex (1:1 sulfate salt); Vincaleukoblastine, 22-oxo-22-Oxovincaleukoblastine; Z-D-Val-Lys(Z)-OH; 22-Oxovincaleukoblastine
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
16 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Wilms tumor DISB6T16 N.A. Approved [1]
Testicular lymphoma DISC2M2N N.A. Approved [1]
Splenic marginal zone lymphoma DISCGTZY N.A. Approved [1]
Primitive neuroectodermal tumor DISFHXHA N.A. Approved [1]
MALT lymphoma DIS1AVVE N.A. Approved [1]
Leukemia DISNAKFL N.A. Approved [1]
Kidney neoplasm DISBNZTN N.A. Approved [1]
Hamartoma DIS0I87H N.A. Approved [1]
Childhood kidney Wilms tumor DIS0NMK3 N.A. Approved [1]
Childhood acute lymphoblastic leukemia DISJ5D6U N.A. Approved [1]
Central nervous system neoplasm DISFC18W N.A. Approved [1]
Burkitt lymphoma DIS9D5XU N.A. Approved [1]
Beckwith-Wiedemann syndrome DISH15GR N.A. Approved [1]
Adult kidney Wilms tumor DIS79FJF N.A. Approved [1]
Plasma cell myeloma DIS0DFZ0 2A83.1 Approved [1]
Nodal marginal zone lymphoma DIS7MP4T 2A85.0 Approved [1]
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⏷ Show the Full List of 16 Indications(s)
1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Medulloblastoma DISZD2ZL 2A00.10 Withdrawn [2]
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2 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Acute lymphocytic leukaemia DISPX75S 2B33.3 Discontinued in Phase 3 [3]
Rhabdomyosarcoma DISNR7MS 2B55 Discontinued in Phase 3 [4]
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2 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Diffuse large B-cell lymphoma DISSACK3 2A81 Discontinued in Phase 2 [5]
Ewing sarcoma DISQYLV3 2B52 Discontinued in Phase 2 [6]
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3 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Classic Hodgkin lymphoma DISV1LU6 N.A. Investigative [1]
Follicular lymphoma DISVEUR6 2A80 Investigative [1]
Neuroblastoma DISVZBI4 2D11.2 Investigative [1]
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References

1 Vincristine FDA Label
2 ClinicalTrials.gov (NCT01007773) Safety of Dexmedetomidine in Severe Traumatic Brain Injury
3 Tecfidera Slow-Titration Study
4 A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium
5 Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant
6 Safety Study of Renal Function in Patients With Chronic Kidney Failure Taking Lumiracoxib or Diclofenac for Arthralgia