Details of Disease

General Information of Disease (ID: DIS8I7CO)

• Disease Name: Binge eating disorder
• Synonyms: binge eating; binge eating disorder
• Definition: Recurrent episodes of over-eating.
• Disease Hierarchy:
  DISVGXN0: Eating disorder
  DIS8I7CO: Binge eating disorder
• Disease Identifiers:
  MONDO ID: MONDO_0005582
  UMLS CUI: C0596170
  MedGen ID: 154543
  SNOMED CT ID: 439960005

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Lisdexamfetamine	DM6W8V5	Approved	Small molecular drug	[1]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 4 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
CNR1	TT6OEDT	moderate	Biomarker	[2]
DRD1	TTZFYLI	moderate	Biomarker	[3]
DRD2	TTEX248	moderate	Biomarker	[3]
DRD4	TTE0A2F	moderate	Biomarker	[3]

References

• [1] Lisdexamfetamine FDA Label
• [2] Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats.Br J Pharmacol. 2013 Jun;169(4):820-33. doi: 10.1111/bph.12014.
• [3] Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder.Physiol Behav. 2017 Oct 15;180:78-90. doi: 10.1016/j.physbeh.2017.08.004. Epub 2017 Aug 15.