Details of Disease

General Information of Disease (ID: DISQZUE7)

Disease Name	Pertussis
Synonyms	infection due to Bordetella pertussis; Bordetella infection; WC - whooping cough; Bordetella pertussis caused disease or disorder; Bordetella pertussis infectious disease; Bordetella pertussis infection; Bordetella pertussis disease or disorder; pertussis; whooping cough
Disease Class	1C12: Whooping cough
Definition	A contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough.
Disease Hierarchy	DISGGAGJ: Respiratory disease DISNIPZL: Bordetellosis DISEM33Q: Infectious disease DISQZUE7: Pertussis
ICD Code	ICD-11 ICD-11: 1C12.Z
Disease Identifiers	MONDO ID MONDO_0005077 MESH ID D014917 UMLS CUI C0043167 MedGen ID 12159 Orphanet ID 1489 SNOMED CT ID 27836007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
DTP-HepB-Polio-Hib	DMVDJ45	Phase 3	NA	[1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ACTG1	TTGAZF9	Strong	Biomarker	[2]
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This Disease Is Related to 6 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ACOT7	OT7C68YV	Strong	Biomarker	[2]
ACTBL2	OTD6B81U	Strong	Biomarker	[2]
ACTG2	OTRDWUO0	Strong	Biomarker	[2]
FHL5	OT6C00Z1	Strong	Biomarker	[2]
POTEM	OT7L2HGH	Strong	Biomarker	[2]
SERPINA3	OT9BP2S0	Strong	Biomarker	[2]
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⏷ Show the Full List of 6 DOT(s)

References

1	Clinical pipeline report, company report or official report of Sanofi Pasteur.
2	Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?.Toxins (Basel). 2019 Jun 18;11(6):354. doi: 10.3390/toxins11060354.