Details of Disease

Disease Name

Mentulagra

Definition

Persistent and usually painful erection that lasts for at least four hours in the absence of physical or psychological stimulation, which can be caused by hematologic disorders, including sickle cell disease and leukemia, spinal cord injuries, and medications.

Disease Hierarchy

DISD8MTH: Erectile dysfunction

DISXSU1Y: Peripheral vascular disease

DISX1G4Y: Priapism

Disease Identifiers

MONDO ID

MONDO_0004745

MESH ID

D011317

UMLS CUI

C0033117

MedGen ID

19462

HPO ID

HP:0200023

Orphanet ID

140949

SNOMED CT ID

6273006

General Information of Disease (ID: DISX1G4Y)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 7 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Darifenacin	DMWXLYZ	Approved	Small molecular drug	[1]
Flavoxate	DMKV4NL	Approved	Small molecular drug	[2]
Methantheline	DM8X4A1	Approved	Small molecular drug	[3]
Solifenacin	DMG592Q	Approved	Small molecular drug	[4]
Tadalafil	DMJZHT1	Approved	Small molecular drug	[5]
Tolterodine	DMSHPW8	Approved	Small molecular drug	[6]
Trospium	DMX6RTG	Approved	Small molecular drug	[7]
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⏷ Show the Full List of 7 Drug(s)

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Oxybutynine	DMJPBAX	Investigative	Small molecular drug	[8]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
PDE5A	TTJ0IQB	Strong	Genetic Variation	[9]
MDM2	TT9TE0O	Definitive	Biomarker	[10]
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References

1	Darifenacin FDA Label
2	Flavoxate FDA Label
3	Methantheline FDA Label
4	Solifenacin FDA Label
5	Tadalafil FDA Label
6	Tolterodine FDA Label
7	Trospium FDA Label
8	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
9	Erectile dysfunction management after failed phosphodiesterase-5-inhibitor trial: a cost-effectiveness analysis.Transl Androl Urol. 2019 Aug;8(4):387-394. doi: 10.21037/tau.2019.03.10.
10	Experimental priapism is associated with increased oxidative stress and activation of protein degradation pathways in corporal tissue.Int J Impot Res. 2010 Nov-Dec;22(6):363-73. doi: 10.1038/ijir.2010.27. Epub 2010 Nov 18.