General Information of This Drug (ID: DML4ZOT)

Drug Name
Lidocaine   DML4ZOT
Synonyms
Alphacaine; Anestacon; Cappicaine; Cuivasil; Dalcaine; Dentipatch; DermaFlex; Dilocaine; Duncaine; EMBOLEX; Esracaine; Gravocain; Isicaina; Isicaine; Jetocaine; LIDOPEN; LQZ; Lanabiotic; Leostesin; Lidocaina; Lidocainum; Lidocaton; Lidoderm; Lignocaine; Lignocainum; Lingocaine; Maricaine; Octocaine; Remicaine; Rucaina; Solcain; Xilina; Xilocaina; Xllina; Xycaine; Xylestesin; Xylesthesin; Xylocain; Xylocaine; Xylocard; Xylocitin; Xylotox; Zingo; After Burn Double Strength Gel; After Burn Double Strength Spray; After Burn Gel; After Burn Spray; Anestacon Jelly; Cito optadren; Emla Cream; Lidocaine Carbonate; Lidocaine Hydrocarbonate; Lidocaine Monohydrochloride; Norwood Sunburn Spray; Rocephin Kit; Solarcaine aloe extraburn relief cream; Xilocaina [Italian]; Xylocaine Dental Ointment; Xylocaine Endotracheal; Xylocaine Test Dose; Xylocaine Viscous; CDS1_000283; L1026_SIGMA; Xylocaine CO2; Dentipatch (TN); ELA-Max; L-Caine; Lida-Mantle; Lidocaina [INN-Spanish]; Lidocaine (VAN); Lidocainum [INN-Latin]; Lidoject-1; Lidoject-2; Octocaine-100; Octocaine-50; Xylocaine (TN); Xylocaine 5% Spinal; Xylocaine-Mpf; Xylocaine-Mpf with Glucose; Xyloneural (free base); Zilactin-L; Lidocaine [USAN:INN:JAN]; Diethylaminoaceto-2,6-xylidide; Lidocaine (JP15/USP/INN); Alfa-Dietilamino-2,6-dimetilacetanilide; Alfa-Dietilamino-2,6-dimetilacetanilide [Italian]; Alpha-Diethylamino-2,6-dimethylacetanilide; Alpha-Diethylaminoaceto-2,6-xylidide; LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE); Omega-Diethylamino-2,6-dimethylacetanilide; Alpha-(Diethylamino)-2,6-acetoxylidide; N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide; N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide; 2-(Diethylamino)-2',6'-acetoxylidide; 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide; 2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide; 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Indication
Disease Entry ICD 11 Status REF
Anaesthesia 9A78.6 Approved [1]
Carpal tunnel syndrome N.A. Approved [2]
Interstitial cystitis GC00.3 Approved [2]
Long QT syndrome BC65.0 Approved [2]
Pain MG30-MG3Z Approved [2]
Pediculus capitis infestation 1G00.0 Approved [2]
Periodontitis DA0C Approved [2]
Postherpetic neuralgia 1E91.5 Approved [2]
Pthirus pubis infestation N.A. Approved [2]
Dysmenorrhea GA34.3 Phase 2 [3]
Chronic pain MG30 Investigative [2]
Neuralgia N.A. Investigative [2]
Premature ejaculation HA03.0Z Investigative [2]
Pruritus EC90 Investigative [2]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Anesthetics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

51 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Capsaicin + Lidocaine DCOIIFN Capsaicin Or Peripheral Nerve Injury (PNI) [4]
Capsaicin + Lidocaine DCRQSPB Capsaicin Knee Osteoarthritis [5]
Clonidine + Lidocaine DCUCYTI Clonidine Pilonidal Sinus [6]
Dexamethasone + Lidocaine DC868R0 Dexamethasone Sciatica [7]
Diazepam + Lidocaine DC1FUPY Diazepam Contraception [8]
Ethanol + Lidocaine DCUVZQI Ethanol Neoplasms, Cystic, Mucinous, and Serous [9]
Fentanyl + Lidocaine DCU67I2 Fentanyl Transient Neurologic Syndrome [10]
Indocyanine green + Lidocaine DCCZGAQ Indocyanine green Lung Cancer [11]
Lidocaine + Sufentanil DC4WQ21 Sufentanil Bronchoscopy [12]
Lidocaine + Nalbuphine DCQ4S6G Nalbuphine Conscious Sedation Failure During Procedure [13]
Lidocaine + Nalbuphine DCZ6JLT Nalbuphine Conscious Sedation Failure During Procedure [13]
Lidocaine + Magnesium Sulfate DC48UEU Magnesium Sulfate General Anesthesia [14]
Lidocaine + Methylprednisolone DC4ZXLO Methylprednisolone Biceps Tendonitis [15]
Lidocaine + Tramadol DC8NYX7 Tramadol Pulpitis [16]
Lidocaine + Ropivacaine DC9ZJ2Y Ropivacaine Pain Management [17]
Lidocaine + Ropivacaine DCBHDWC Ropivacaine Anesthesia [18]
Lidocaine + Remifentanil DCBSUXF Remifentanil Cough [19]
Lidocaine + Sucrose DCGP05P Sucrose Pain [20]
Lidocaine + Naproxen DCH6BSY Naproxen Contraception [21]
Lidocaine + Propofol DCVBR2M Propofol Pain [22]
Lidocaine + Dofetilide DCROH2U Dofetilide Drug-induced QT Prolongation [23]
Oxilan iohexol + Lidocaine DCZY7N4 Oxilan iohexol Chronic Low-back Pain [24]
Triamcinolone + Lidocaine DCCZGN8 Triamcinolone Trigger Finger [25]
Guanfacine + Lidocaine DCFCPNK Guanfacine Trigeminal Neuralgia [26]
Lidocaine + Morphine DC2B6D3 Morphine Cancer Debulking [27]
Lidocaine + Methylprednisolone DCHZT3E Methylprednisolone Knee Joint Osteoarthrosis [28]
Lidocaine + Diclofenac DCWQL5E Diclofenac Renal Colic [29]
Nortriptyline + Lidocaine DCFHKA9 Nortriptyline Vestibulodynia [30]
Atracurium + Lidocaine DCGC9L2 Atracurium Postoperative Pain [31]
Epinephrine + Lidocaine DCC0ZTM Epinephrine Irreversible Pulpitis [32]
Ketamine + Lidocaine DCECJVF Ketamine Septic Shock [33]
Ketamine + Lidocaine DCVAQBE Ketamine Postoperative Pain [34]
Ketorolac + Lidocaine DC3KLDA Ketorolac Postoperative Pain [35]
Lidocaine + Sevoflurane DC3N734 Sevoflurane Colonic Cancer [36]
Lidocaine + Remifentanil DC77CLY Remifentanil Stroke [37]
Lidocaine + Tramadol DCJVZWT Tramadol Pain Management [38]
Lidocaine + Acetaminophen DCN4HA7 Acetaminophen Postoperative Pain [35]
Lidocaine + Sodium bicarbonate DCOUW4O Sodium bicarbonate Local Anesthesia [39]
Epinephrine + Lidocaine DCNLSFT Epinephrine Surgery [40]
Esmolol + Lidocaine DCEGK3Y Esmolol Hemodynamic Instability [41]
Fentanyl + Lidocaine DCFEH6M Fentanyl Coronary Artery Disease [42]
Ketorolac + Lidocaine DC487K6 Ketorolac Pain [43]
Lidocaine + Cisatracurium DCZ372P Cisatracurium Neuromuscular Block [44]
Lidocaine + Cefazolin DC8FV2P Cefazolin Vitreoretinal Surgery [45]
Lidocaine + Nitroglycerin DCF13HA Nitroglycerin Radial Artery Spasm [46]
Lidocaine + Propofol DCG57SD Propofol Topical Anesthesia [47]
Lidocaine + Sodium bicarbonate DCNUPTX Sodium bicarbonate Local Anesthesia [48]
Lidocaine + Midazolam DCOCUWU Midazolam Critical Illness [49]
Lidocaine + Midazolam DCPKYRT Midazolam Sedation, Conscious [50]
Triamcinolone + Lidocaine DC4U2ZP Triamcinolone Shoulder Pain [51]
Triamcinolone + Lidocaine DC2ART1 Triamcinolone Shoulder Pain [51]
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⏷ Show the Full List of 51 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2623).
2 Lidocaine FDA Label
3 ClinicalTrials.gov (NCT00651313) Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods). U.S. National Institutes of Health.
4 ClinicalTrials.gov (NCT01416116) Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch
5 ClinicalTrials.gov (NCT03576508) A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis
6 ClinicalTrials.gov (NCT02539693) Sacrococcygeal Local Anesthesia With Different Doses of Clonidine for Pilonidal Sinus Surgery
7 ClinicalTrials.gov (NCT03924791) Transforaminal Epidural Injection in Acute Sciatica
8 ClinicalTrials.gov (NCT02799641) Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing IUD
9 ClinicalTrials.gov (NCT02158039) Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms
10 ClinicalTrials.gov (NCT01794247) Intrathecal Magnesium for Same-day-surgery
11 ClinicalTrials.gov (NCT00540982) Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction
12 ClinicalTrials.gov (NCT03738137) Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
13 ClinicalTrials.gov (NCT02820051) Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy
14 ClinicalTrials.gov (NCT01342510) Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol
15 ClinicalTrials.gov (NCT02591953) Prospective Clinical Analysis of Ultrasound-guided Biceps Corticosteroid Injections
16 ClinicalTrials.gov (NCT05538052) Use of Tramadol Intraligamentary Injections
17 ClinicalTrials.gov (NCT02576015) The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty
18 ClinicalTrials.gov (NCT02554864) Location of Injection of Local Anesthetics in the Adductor Canal Block
19 ClinicalTrials.gov (NCT04455711) The Effect of Lidocaine on Smooth Emergence With Double Lumen Tube
20 ClinicalTrials.gov (NCT00519207) Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture
21 ClinicalTrials.gov (NCT02769247) Efficacy of Intrauterine Lidocaine and Naproxen for Pain Control With Intrauterine Device Insertion
22 ClinicalTrials.gov (NCT02512783) Decreasing Propofol Injection Pain by Pre-Treatment With Lidocaine in Pediatric Procedural Sedation
23 ClinicalTrials.gov (NCT02308748) Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
24 ClinicalTrials.gov (NCT05930236) Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method
25 ClinicalTrials.gov (NCT02084706) Needle-Free Injection of Lidocaine for Local Anesthesia Prior to Trigger Digit Injection
26 ClinicalTrials.gov (NCT03865940) Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy
27 ClinicalTrials.gov (NCT05017246) Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
28 ClinicalTrials.gov (NCT02253966) Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
29 ClinicalTrials.gov (NCT03199924) Treatment of Renal Colic in the Emergency Departement (ED).
30 ClinicalTrials.gov (NCT03844412) Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
31 ClinicalTrials.gov (NCT02920905) Atracurium Mixed With Magnesium Sulfate Versus Atracurium Alone as Adjuvant to Lidocaine in IVRA
32 ClinicalTrials.gov (NCT02807298) 4% Articaine and 2% Lidocaine by Intraligamentary Technique in Irreversible Pulpitis
33 ClinicalTrials.gov (NCT03640468) Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients
34 ClinicalTrials.gov (NCT01983020) Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery
35 ClinicalTrials.gov (NCT03485625) Adjuncts to IVRA, a Comparison Between Ketorolac and Paracetamol
36 ClinicalTrials.gov (NCT04316013) Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial
37 ClinicalTrials.gov (NCT02822144) General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke
38 ClinicalTrials.gov (NCT05928520) Pain Management in Pediatric Adenotonsillectomy
39 ClinicalTrials.gov (NCT02726737) Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block
40 ClinicalTrials.gov (NCT01964586) Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.
41 ClinicalTrials.gov (NCT03612492) The Effects of Lidocaine and Esmolol on Attenuation of Hemodynamic Response to Orotracheal Intubation
42 ClinicalTrials.gov (NCT02683707) The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial (PACIFY)
43 ClinicalTrials.gov (NCT02902770) Intravenous Lidocaine and Ketorolac for Pain Management
44 ClinicalTrials.gov (NCT02483611) Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
45 ClinicalTrials.gov (NCT02324166) Cefazolin-Lidocaine Combination Solution to Reduce Antibiotic Pain
46 ClinicalTrials.gov (NCT02832115) Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention
47 ClinicalTrials.gov (NCT02507440) Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's
48 ClinicalTrials.gov (NCT02647892) Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia
49 ClinicalTrials.gov (NCT02635802) the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation
50 ClinicalTrials.gov (NCT02314546) Intranasal Midazolam in Children as a Pre-Operative Sedative
51 ClinicalTrials.gov (NCT02592629) The Efficacy of Local Anesthetics to Reduce Shoulder Pain Post-Steroid Injections