Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM42PFT)

Drug Name
E-3810 Drug Info
Synonyms Lucitanib; AL-3810; E-3810, EOS
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Cross-matching ID
PubChem CID
25031915
ChEBI ID
CHEBI:65209
CAS Number
CAS 1058137-23-7
TTD Drug ID
DM42PFT

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Vascular endothelial growth factor receptor 3 (FLT-4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fruquintinib DMHOSCQ Colorectal cancer 2B91.Z Approved [3]
Tivozanib DMUKC5L Renal cell carcinoma 2C90 Approved [4]
Sulfatinib DMPOTM4 Neuroendocrine cancer 2B72.1 Phase 3 [5]
PI-88 DMGZPX6 Hepatocellular carcinoma 2C12.02 Phase 3 [6]
Taberminogene vadenovec DMW5PHL Vascular restinosis BE2Z Phase 3 [7]
ABT-869 DMREDYP Solid tumour/cancer 2A00-2F9Z Phase 3 [8]
MGCD516 DM752PU Solid tumour/cancer 2A00-2F9Z Phase 2/3 [9]
Famitinib DMSFWT7 Solid tumour/cancer 2A00-2F9Z Phase 2 [10]
VATALANIB DMY0UEQ Solid tumour/cancer 2A00-2F9Z Phase 2 [11]
MK-2461 DM21WBH Alzheimer disease 8A20 Phase 1/2 [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Fibroblast growth factor receptor 1 (FGFR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [13]
Intedanib DMSTA36 Colorectal cancer 2B91.Z Approved [14]
Pemigatinib DM819JF Cholangiocarcinoma 2C12.10 Approved [15]
Infigratinib DMNKBEC Cholangiocarcinoma 2C12.10 Approved [16]
Sulfatinib DMPOTM4 Neuroendocrine cancer 2B72.1 Phase 3 [5]
ARQ-087 DM02BVQ Intrahepatic cholangiocarcinoma 2C12.10 Phase 3 [17]
AZD4547 DM3827C Solid tumour/cancer 2A00-2F9Z Phase 2/3 [18]
Debio 1347 DMZW50O Solid tumour/cancer 2A00-2F9Z Phase 2 [19]
AM-001 DMGVQI8 Actinic keratosis EK90.0 Phase 2 [20]
FGF-1 DMXMC8I Coronary heart disease BA80.Z Phase 2 [21]
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Drug(s) Targeting Platelet-derived growth factor receptor alpha (PDGFRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [22]
Ripretinib DM958QB Gastrointestinal stromal tumour 2B5B Approved [23]
Olaratumab DMNYOIX Soft tissue sarcoma 2B57 Approved [24]
Avapritinib DMK2GZX Gastrointestinal stromal tumour 2B5B Approved [25]
CP-868596 DMZIM37 Gastrointestinal cancer 2C11 Phase 3 [26]
Famitinib DMSFWT7 Solid tumour/cancer 2A00-2F9Z Phase 2 [10]
XL-820 DMMHX9K Solid tumour/cancer 2A00-2F9Z Phase 2 [27]
MP470 DMELUAK Solid tumour/cancer 2A00-2F9Z Phase 2 [28]
MEDI-575 DMI9WVM Glioblastoma multiforme 2A00.0 Phase 2 [29]
Pyridine derivative 18 DMBZMYT N. A. N. A. Patented [30]
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Drug(s) Targeting Fibroblast growth factor receptor 2 (FGFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pemigatinib DM819JF Cholangiocarcinoma 2C12.10 Approved [15]
Interferon Alfa-2a, Recombinant DMUTZ8S Chronic HCV-1 infection 1E51.1 Approved [31]
Palifermin DM9JOYP Oral mucositis DA01.11 Approved [32]
Trafermin DMLKI2B Periodontitis DA0C Phase 3 [33]
Debio 1347 DMZW50O Solid tumour/cancer 2A00-2F9Z Phase 2 [19]
LY2874455 DMZ0DMY Solid tumour/cancer 2A00-2F9Z Phase 2 [34]
MK-2461 DM21WBH Alzheimer disease 8A20 Phase 1/2 [12]
AEE-788 DMEOS5K Solid tumour/cancer 2A00-2F9Z Phase 1/2 [35]
BAY1179470 DM7L91K Solid tumour/cancer 2A00-2F9Z Phase 1 [36]
Alofanib DMIEKTF Gastric adenocarcinoma 2B72 Phase 1 [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Platelet-derived growth factor receptor beta (PDGFRB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [38]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [22]
Becaplermin DM1R5X4 Diabetic complication 5A2Y Approved [39]
Famitinib DMSFWT7 Solid tumour/cancer 2A00-2F9Z Phase 2 [10]
XL-820 DMMHX9K Solid tumour/cancer 2A00-2F9Z Phase 2 [27]
MK-2461 DM21WBH Alzheimer disease 8A20 Phase 1/2 [12]
SNN-0031 DM2X3BR Brain injury NA07.Z Phase 1/2 [40]
TAK-593 DMNFZOT Solid tumour/cancer 2A00-2F9Z Phase 1 [41]
Pyridine derivative 18 DMBZMYT N. A. N. A. Patented [30]
PMID25656651-Compound-21a DMCKAON N. A. N. A. Patented [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Vascular endothelial growth factor receptor 1 (FLT-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fruquintinib DMHOSCQ Colorectal cancer 2B91.Z Approved [3]
Tivozanib DMUKC5L Renal cell carcinoma 2C90 Approved [4]
Sulfatinib DMPOTM4 Neuroendocrine cancer 2B72.1 Phase 3 [5]
Famitinib DMSFWT7 Solid tumour/cancer 2A00-2F9Z Phase 2 [10]
X-82 DMW1NKO Age-related macular degeneration 9B75.0 Phase 2 [43]
OCV-101 DMT9QI2 Pancreatic cancer 2C10 Phase 2 [44]
LY3012212 DMRVEHY Arteriosclerosis BD40 Phase 2 [45]
OTSGC-A24 DMN0ZQ5 Colorectal cancer 2B91.Z Phase 1/2 [46]
CEP-11981 DMYDTJ6 Solid tumour/cancer 2A00-2F9Z Phase 1 [47]
EW-A-401 DM3VC6T Peripheral vascular disease BD4Z Phase 1 [48]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Vascular endothelial growth factor receptor 2 (KDR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [38]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [13]
Regorafenib DMHSY1I Gastrointestinal stromal tumour 2B5B Approved [49]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [50]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [51]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [35]
Pazopanib HCl DM6U9CQ Renal cell carcinoma 2C90 Approved [52]
Fruquintinib DMHOSCQ Colorectal cancer 2B91.Z Approved [3]
Cabozantinib DMIYDT4 Medullary thyroid gland carcinoma Approved [53]
Tivozanib DMUKC5L Renal cell carcinoma 2C90 Approved [4]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Fibroblast growth factor receptor 3 (FGFR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pemigatinib DM819JF Cholangiocarcinoma 2C12.10 Approved [15]
Trapidil DMY67U8 Acute coronary syndrome BA41 Phase 4 [54]
TKI258 DMYLT67 Renal cell carcinoma 2C90 Phase 3 [35]
BMS-582664 DMDAN8H Hepatocellular carcinoma 2C12.02 Phase 3 [35]
Debio 1347 DMZW50O Solid tumour/cancer 2A00-2F9Z Phase 2 [19]
B-701 DMOMDA4 Bladder cancer 2C94 Phase 2 [55]
Recifercept DML8N3Y Achondroplasia LD24.00 Phase 2 [56]
MK-2461 DM21WBH Alzheimer disease 8A20 Phase 1/2 [12]
AEE-788 DMEOS5K Solid tumour/cancer 2A00-2F9Z Phase 1/2 [35]
Anti-FGFR3 DM6QENU Multiple myeloma 2A83 Phase 1 [57]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor receptor 1 (FGFR1) TTRLW2X FGFR1_HUMAN Inhibitor [2]
Fibroblast growth factor receptor 2 (FGFR2) TTGJVQM FGFR2_HUMAN Inhibitor [2]
Fibroblast growth factor receptor 3 (FGFR3) TTST7KB FGFR3_HUMAN Inhibitor [2]
Platelet-derived growth factor receptor alpha (PDGFRA) TT8FYO9 PGFRA_HUMAN Inhibitor [2]
Platelet-derived growth factor receptor beta (PDGFRB) TTI7421 PGFRB_HUMAN Inhibitor [2]
Vascular endothelial growth factor receptor 1 (FLT-1) TT2Q6G1 VGFR1_HUMAN Inhibitor [2]
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Inhibitor [2]
Vascular endothelial growth factor receptor 3 (FLT-4) TTDCBX5 VGFR3_HUMAN Inhibitor [2]

References

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