Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCAYXF)

Drug Name
alpha-methyl-5-HT Drug Info
Synonyms alpha-Me-5-HT; alpha-methylserotonin
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2107
ChEBI ID
CHEBI:48295
CAS Number
CAS 304-52-9
TTD Drug ID
DMCAYXF

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting 5-HT 1D receptor (HTR1D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [10]
Eletriptan DMW649X Migraine 8A80 Approved [11]
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [11]
Frovatriptan DM7RE8P Migraine 8A80 Approved [11]
Sumatriptan DMVYXR8 Cluster headache 8A81.0 Approved [12]
Rizatriptan DMDJMA3 Migraine 8A80 Approved [13]
Almogran DM7I64Z Migraine 8A80 Approved [14]
Neu-P11 DMIQDFW Alzheimer disease 8A20 Phase 2 [15]
FKB01MD DM2O7NM N. A. N. A. Phase 2 [16]
NXN-188 DMMBAIH Migraine 8A80 Phase 2 [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 6 receptor (HTR6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
LU AE58054 DMWGRQD Schizophrenia 6A20 Phase 3 [18]
SB-742457 DM6L4ZT Alzheimer disease 8A20 Phase 3 [19]
AVN 211 DMVB4OS Schizophrenia 6A20 Phase 2/3 [20]
SYN120 DMDF7XB Parkinson disease 8A00.0 Phase 2 [21]
AVN 101 DMJFLBC Alzheimer disease 8A20 Phase 2 [20]
SYN-120 DMPW0UL Alzheimer disease 8A20 Phase 2 [22]
PF-05212377 DMPVQYR Alzheimer disease 8A20 Phase 2 [23]
AVN 322 DMK2LGM Cognitive impairment 6D71 Phase 2 [19]
SAM-531 DMHVJZ6 Alzheimer disease 8A20 Phase 2 [24]
SUVN-502 DMQD753 Alzheimer disease 8A20 Phase 2 [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 2B receptor (HTR2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [26]
Triflupromazine DMKFQJP Nausea MD90 Approved [27]
Minaprine DM0EP7M Depression 6A70-6A7Z Approved [28]
SPN-812 DMTV7XH Attention deficit hyperactivity disorder 6A05.Z Phase 4 [29]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [30]
PRX-08066 DMR7H2V Pulmonary arterial hypertension BB01.0 Phase 2 [31]
Pyrimidine derivative 29 DMVOYJ8 N. A. N. A. Patented [32]
Pyrimidine derivative 26 DM90WKN N. A. N. A. Patented [32]
Pyrimidine derivative 23 DM5MLQU N. A. N. A. Patented [32]
Pyrimidine derivative 25 DM51MFS N. A. N. A. Patented [32]
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Drug(s) Targeting 5-HT 2A receptor (HTR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [26]
ZOTEPINE DMF3VXA Anxiety disorder 6B00-6B0Z Approved [33]
Iloperidone DM6AUFY Schizophrenia 6A20 Approved [34]
Flibanserin DM70DTN Depression 6A70-6A7Z Approved [35]
Lurasidone hydrochloride DMCVPXO Schizophrenia 6A20 Approved [36]
Aniracetam DMOIFW0 Cerebrovascular ischaemia 8B1Z Approved [37]
lumateperone tosylate DMQ8HOJ Schizophrenia 6A20 Approved [38]
Sarpogrelate DMGLP6S Diabetic complication 5A2Y Approved [39]
Pimavanserin DMR7IVC Parkinson disease 8A00.0 Approved [40]
Zicronapine DMP8ESD Schizophrenia 6A20 Phase 3 [41]
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Drug(s) Targeting 5-HT 4 receptor (HTR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisapride DMY7PED Gastroesophageal reflux disease DA22.Z Approved [42]
Tegaserod DM3XYD1 Irritable bowel syndrome DD91.0 Approved [43]
R0-93877 DMM4U9G Constipation DD91.1 Approved [12]
HTF 919 DM78G6F Constipation DD91.1 Approved [44]
Mosapride DM2VOQ3 N. A. N. A. Phase 4 [45]
Renzapride DM7HQNX Irritable bowel syndrome DD91.0 Phase 3 [46]
Lintopride DMSHGWN Nausea MD90 Phase 2 [47]
TD-8954 DM3C9NV Gastrointestinal disease DE2Z Phase 2 [48]
SB-207266A DM27KFY Irritable bowel syndrome DD91.0 Phase 2 [12]
YKP-GI DM740LV Constipation DD91.1 Phase 2 [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting 5-HT 1F receptor (HTR1F)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [50]
Lasmiditan DMXLVDT Migraine 8A80 Approved [51]
LY-334370 DM43O9N Migraine 8A80 Phase 2 [52]
5-CT DM260KD Discovery agent N.A. Investigative [50]
TFMPP DMAC8TP Discovery agent N.A. Investigative [4]
1-naphthylpiperazine DM6BIWK Discovery agent N.A. Investigative [50]
BRL-15572 DMM61Y2 Discovery agent N.A. Investigative [53]
2-methyl-5-HT DM1S5CB N. A. N. A. Investigative [4]
WAY-466 DMMOH51 Discovery agent N.A. Investigative [54]
[125I]LSD DMP69QG Discovery agent N.A. Investigative [55]
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Drug(s) Targeting 5-HT 2C receptor (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [26]
Lorcaserin DMG6OYJ Obesity 5B81 Approved [56]
Tramadol DMRQD04 Osteoarthritis FA00-FA05 Approved [57]
Mirtazapine DML53ZJ Depression 6A70-6A7Z Approved [58]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [59]
Methysergide DM1EF73 Migraine 8A80 Approved [60]
Eltoprazine DMW6C81 Attention deficit hyperactivity disorder 6A05.Z Phase 3 [61]
M100907 DM7ZFBA Sleep-wake disorder 7A00-7B2Z Phase 3 [62]
SR46349B DM1ODMR Primary insomnia 7A00 Phase 3 [63]
Vabicaserin DM9GZW6 Psychotic disorder 6A20-6A25 Phase 2 [30]
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Drug(s) Targeting 5-HT 1E receptor (HTR1E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metergolin DMJFP6G Hyperprolactinaemia 5A60.1 Approved [3]
5-CT DM260KD Discovery agent N.A. Investigative [3]
TFMPP DMAC8TP Discovery agent N.A. Investigative [3]
1-naphthylpiperazine DM6BIWK Discovery agent N.A. Investigative [3]
BRL-15572 DMM61Y2 Discovery agent N.A. Investigative [53]
2-methyl-5-HT DM1S5CB N. A. N. A. Investigative [4]
m-chlorophenylpiperazine DMM1J2D Discovery agent N.A. Investigative [3]
EDMT DMS3AXK Discovery agent N.A. Investigative [64]
9-OH-risperidone DMGORXQ Discovery agent N.A. Investigative [65]
[3H]5-HT DMYJXV7 Discovery agent N.A. Investigative [66]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1D receptor (HTR1D) TT6MSOK 5HT1D_HUMAN Agonist [2]
5-HT 1E receptor (HTR1E) TTCPG9S 5HT1E_HUMAN Agonist [3]
5-HT 1F receptor (HTR1F) TT0MI3F 5HT1F_HUMAN Agonist [4]
5-HT 2A receptor (HTR2A) TTJQOD7 5HT2A_HUMAN Agonist [5]
5-HT 2B receptor (HTR2B) TT0K1SC 5HT2B_HUMAN Agonist [6]
5-HT 2C receptor (HTR2C) TTWJBZ5 5HT2C_HUMAN Agonist [7]
5-HT 4 receptor (HTR4) TT07C3Y 5HT4R_HUMAN Agonist [8]
5-HT 6 receptor (HTR6) TTJS8PY 5HT6R_HUMAN Agonist [9]

References

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