General Information of Drug (ID: DMPAEK5)

Drug Name
SOU-001 Drug Info
Synonyms AA-10020; DRP-001
Indication
Disease Entry ICD 11 Status REF
Urinary incontinence MF50.2 Discontinued in Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMPAEK5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Patented Agent(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methamphetamine DMPM4SK Anxiety Approved [3]
Propericiazine DME9JNL Psychiatric disorder 6E8Z Approved [4]
Methoxamine DMF5XQH Hypertension BA00-BA04 Approved [5]
Phendimetrazine DM6TS1N Obesity 5B81 Approved [6]
MEDETOMIDINE DMX9Y7V Pain MG30-MG3Z Phase 2 [7]
TIOSPIRONE DME5QDP N. A. N. A. Discontinued in Phase 3 [8]
Sunepitron DM6M8ZX N. A. N. A. Discontinued in Phase 3 [9]
MAZAPERTINE DMRHYAU N. A. N. A. Discontinued in Phase 2 [10]
SNAP-5089 DMROJEN Heart arrhythmia BC65 Terminated [11]
WB-4101 DMQU8B1 N. A. N. A. Terminated [12]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxazosin DM9PLRH Benign prostatic hyperplasia GA90 Approved [13]
Armodafinil DMGB035 Malignant glioma 2A00.0 Approved [14]
Alfuzosin DMZVMKF Benign prostatic hyperplasia GA90 Approved [15]
Moxisylyte DMFCLYW Erectile dysfunction HA01.1 Approved [16]
Terazosin DM3JCVS Benign prostatic hyperplasia GA90 Approved [17]
Bunazosin DM4I8O7 Glaucoma/ocular hypertension 9C61 Approved [18]
Trimazosin DM1QLST Congestive heart failure BD10 Approved [19]
MEDETOMIDINE DMX9Y7V Pain MG30-MG3Z Phase 2 [7]
DL-017 DMM8GZT Hypertension BA00-BA04 Phase 1 [20]
PMID30124346-Compound-LDT8 DM5MUNG Benign prostatic hyperplasia GA90 Patented [21]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SILODOSIN DMJSBT6 Benign prostatic hyperplasia GA90 Approved [22]
NAFTOPIDIL DMQ8R4E Hypertension BA00-BA04 Approved [22]
Tamsulosin DM5QF9V Benign prostatic hyperplasia GA90 Approved [23]
Xatral DMLHOA0 Benign prostatic hyperplasia GA90 Approved [24]
Dutasteride + tamsulosin DM6P8HU Benign prostatic hyperplasia GA90 Phase 3 [25]
Besipirdine DMLVNTA Cognitive impairment 6D71 Phase 3 [26]
MEDETOMIDINE DMX9Y7V Pain MG30-MG3Z Phase 2 [7]
PMID30124346-Compound-LDT8 DM5MUNG Benign prostatic hyperplasia GA90 Patented [21]
PMID30124346-Compound-LDT66 DMJMTNL Benign prostatic hyperplasia GA90 Patented [21]
TIOSPIRONE DME5QDP N. A. N. A. Discontinued in Phase 3 [8]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor alpha-1A (ADRA1A) TTNGILX ADA1A_HUMAN Modulator [2]
Adrenergic receptor alpha-1B (ADRA1B) TTBRKXS ADA1B_HUMAN Modulator [2]
Adrenergic receptor alpha-1D (ADRA1D) TT34BHT ADA1D_HUMAN Modulator [2]

References

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15 Alfuzosin: a review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia. Drugs. 2002;62(4):633-53.
16 Pharmacokinetics of moxisylyte in healthy volunteers after intracavernous injection of increasing doses. Eur J Clin Pharmacol. 1996;49(5):411-5.
17 Induction of prostate apoptosis by alpha1-adrenoceptor antagonists: mechanistic significance of the quinazoline component. Prostate Cancer Prostatic Dis. 2002;5(2):88-95.
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26 Alpha-Adrenergic activity and cardiovascular effects of besipirdine HCl (HP 749) and metabolite P7480 in vitro and in the conscious rat and dog. J Pharmacol Exp Ther. 1997 Apr;281(1):337-46.