Details of the Drug Reposition

General Information of This Drug (ID: DMZ7XNQ)

Drug Name
Tacrolimus   DMZ7XNQ
Synonyms
Advagraf; Fujimycin; Graceptor; Modigraf; Prograf; Protopic; Protopy; Tacarolimus; Tsukubaenolide; Tacrolimus anhydrous; FK 506; FK5; FK506; FR 900506; FR900506; K506; L 679934; Advagraf (TN); FR-900506; Fk-506; L-679934; LCP-Tacro; Prograf (TN); Protopic (TN); Tacrolimus (INN); Tacrolimus (Prograf); Tacrolimus (anhydrous); (-)-FK 506; 15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
Therapeutic Class
Immunosuppressive Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
13 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Testicular lymphoma DISC2M2N N.A. Approved [1]
Splenic marginal zone lymphoma DISCGTZY N.A. Approved [1]
Small intestine lymphoma DISDOS6S N.A. Approved [1]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified DIS5OHQF N.A. Approved [1]
MALT lymphoma DIS1AVVE N.A. Approved [1]
Leukemia DISNAKFL N.A. Approved [1]
Hepatosplenic T-cell lymphoma DIS7KMY9 N.A. Approved [1]
Myeloproliferative neoplasm DIS5KAPA 2A20 Approved [1]
Recurrent adult burkitt lymphoma DIS6V60A 2A85.6 Approved [1]
Large granular lymphocytic leukemia DISHOPPI 2A90.1 Approved [1]
Lupus nephritis DISCVGPZ 4A40.0Y Approved [1]
Graft-versus-host disease DIS0QADF 4B24 Approved [1]
Kidney transplant rejection DISJ1FYS NE84 Approved [1]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 Indications(s)
1 Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ocular allergy DIS38BN3 4A81 Phase 3 [2]
------------------------------------------------------------------------------------
1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Vitiligo DISR05SL ED63.0 Discontinued in Phase 2 [3]
------------------------------------------------------------------------------------
1 Discontinued in Phase 1 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Post-transplant lymphoproliferative disorder DISTS43D 2B32 Discontinued in Phase 1 [4]
------------------------------------------------------------------------------------
1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Classic Hodgkin lymphoma DISV1LU6 N.A. Investigative [1]
------------------------------------------------------------------------------------

References

1 Tacrolimus FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6784).
3 Darbepoetin Alfa and Anemia of Cancer
4 Treated Blood Cells, Cyclophosphamide, Fludarabine Phosphate, and Aldesleukin in Treating Patients With Cancer