General Information of Disease (ID: DIS1RRCY)

Disease Name Melanoma
Synonyms melanoma, malignant; melanoma; malignant melanoma; Naevocarcinoma; melanoma (disease)
Disease Class 2C30: Melanoma
Definition
A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.
Disease Hierarchy
DISOXEAY: Melanocytic neoplasm
DIS1RRCY: Melanoma
ICD Code
ICD-11
ICD-11: 2C30
ICD-9
ICD-9: 172
Expand ICD-9
172
Disease Identifiers
MONDO ID
MONDO_0005105
MESH ID
D008545
UMLS CUI
C0025202
MedGen ID
9944
HPO ID
HP:0002861
Orphanet ID
411533
SNOMED CT ID
1162635006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 39 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
99mTc-depreotide DMM4DV4 Approved NA [1]
ARRY-162 DM1P6FR Approved Small molecular drug [2]
Atezolizumab DMMF8U0 Approved Monoclonal antibody [3]
Avelumab DMSZLJR Approved Monoclonal antibody [4]
Bavencio DMU9C8F Approved Monoclonal antibody [3]
Dabrafenib DMX6OE3 Approved Small molecular drug [5]
Dacarbazine DMNPZL4 Approved Small molecular drug [6]
Durvalumab DM4PVDY Approved Monoclonal antibody [4]
HybriCell DMCV6X9 Approved NA [1]
Hydroxyurea DMOQVU9 Approved Small molecular drug [7]
Imiquimod DM1TMA3 Approved Small molecular drug [8]
Ingenol mebutate DMK1CZJ Approved Small molecular drug [9]
Interferon Alfa-2b DMWCQP4 Approved Small molecular drug [1]
Ipilimumab DMJTIYK Approved Monoclonal antibody [10]
Isoproterenol DMK7MEY Approved Small molecular drug [11]
Lapatinib DM3BH1Y Approved Small molecular drug [12]
Lenvatinib DMB1IU4 Approved Small molecular drug [13]
LGX818 DMNQXV8 Approved Small molecular drug [2]
Lovastatin DM9OZWQ Approved Small molecular drug [14]
Melacine DMXC544 Approved NA [1]
MK-3475 DMBYNW0 Approved Monoclonal antibody [15]
Nivolumab DMAB9QE Approved Monoclonal antibody [16]
Omaveloxolone DMLMNFX Approved Small molecular drug [3]
Osimertinib DMRJLAT Approved Small molecular drug [17]
Palladium Pd 103 DMN3A34 Approved Small molecular drug [1]
Pembrolizumab DMFQEA6 Approved Monoclonal antibody [5]
Romidepsin DMT5GNL Approved Small molecular drug [19]
Talimogene Laherparepvec DMKBW5C Approved Vaccine [1]
Tc-99m tilmanocept DMH3SSE Approved NA [20]
Tebentafusp DMUJ1WV Approved Monoclonal antibody [21]
Temozolomide DMKECZD Approved Small molecular drug [22]
Teplizumab DMZ3P6C Approved Antibody [23]
Thymalfasin DMADCYE Approved Small molecular drug [24]
Toripalimab DMSGA6Z Approved in China Monoclonal antibody [25]
Trametinib DM2JGQ3 Approved Small molecular drug [26]
Treosulfan DMDIOAR Approved Small molecular drug [27]
Vemurafenib DM62UG5 Approved Small molecular drug [28]
Vindesine DMVR628 Approved Small molecular drug [29]
HBI-8000 DMDWYUN Registered Small molecular drug [4]
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⏷ Show the Full List of 39 Drug(s)
This Disease is Treated as An Indication in 1 Approved
Drug Name Drug ID Highest Status Drug Type REF
Relatlimab DM28AZV Approved NA [18]
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This Disease is Treated as An Indication in 161 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
MPL-containing Pollinex allergy desensitization vaccine DM4W8QM Preregistration NA [30]
OncoVAX DMMPRAX Preregistration NA [31]
177Lu-DOTA-octreotate DMP5L8S Phase 3 NA [32]
ABT-888 DM4HYMS Phase 3 Small molecular drug [13]
AMD-070 DMVOY6B Phase 3 Small molecular drug [4]
BMS-986205 DM3MAYQ Phase 3 NA [4]
Canvaxin DM90TDD Phase 3 NA [33]
Cotellic DMF9M57 Phase 3 Small molecular drug [3]
Daromun DMC4O8L Phase 3 NA [4]
GMK DM55ZM1 Phase 3 Small molecular drug [34]
IMO-2125 DM735FA Phase 3 NA [4]
INCB24360 DMIJGT9 Phase 3 Small molecular drug [4]
Javelin DMCNF7E Phase 3 NA [35]
MAGE-A3 immunotherapeutic DMI0GZT Phase 3 NA [36]
Melanoma vaccine DMQEC6Z Phase 3 Vaccine [37]
Melanoma vaccine, University of Virginia DMIPXTV Phase 3 NA [9]
Melapuldencel-T DMNKG6L Phase 3 NA [38]
Mitumomab DMY6VPA Phase 3 Monoclonal antibody [39]
MPDL-3280A DM9K3LM Phase 3 Monoclonal antibody [40]
Multi-epitope peptide melanoma vaccine DMZPEHY Phase 3 Vaccine [37]
NKTR 214 DM376WT Phase 3 NA [41]
NKTR-214 DMACYW6 Phase 3 Recombinant protein [42]
Oblimersen DM7KI4E Phase 3 NA [43]
PDR001 DM53J6B Phase 3 Antibody [44]
Pegargiminase DMQKFWX Phase 3 Recombinant protein [13]
PV-10 DM95UYC Phase 3 Small molecular drug [45]
QS-21 DMWHLMD Phase 3 NA [46]
RemuneX DMCJUL5 Phase 3 NA [47]
SD-101 DMAMTGI Phase 3 Oligonucleotide [4]
Selumetinib DMC7W6R Phase 3 Small molecular drug [48]
Seviprotimut-L DMQW6B6 Phase 3 NA [49]
SNDX-275 DMH7W9X Phase 3 Small molecular drug [4]
Spartalizumab DM4TOEQ Phase 3 Monoclonal antibody [50]
Tesetaxel DM9LFYN Phase 3 Small molecular drug [51]
Tilsotolimod DMGYK2N Phase 3 Oligonucleotide [52]
Velimogene aliplasmid DMJBU9V Phase 3 NA [53]
FX005 DMG59CB Phase 2/3 Small molecular drug [54]
Imprime PGG DMIUA3M Phase 2/3 NA [4]
NLG8189 DM0798Z Phase 2/3 Small molecular drug [4]
OT-101 DMCTRLN Phase 2/3 Antisense oligonucleotide [3]
ABX-IL8 DMCZFMS Phase 2 Antibody [55]
Ad-RTS-hIL-12 DMCNTFW Phase 2 Gene therapy [56]
AG140699 DMA9FKY Phase 2 NA [57]
Anti-CD3 activated vaccine-primed lymphocytes DMNH84A Phase 2 NA [58]
Antigen-pulsed dendritic cell vaccine DMMYHSV Phase 2 NA [59]
APN-301 DM32YTJ Phase 2 NA [60]
APX005M DMX2P5G Phase 2 Antibody [61]
ARC-100 DMF6GK1 Phase 2 Small molecular drug [62]
Autologous anti-gp100 T-cell receptor gene-engineered peripheral blood lymphocytes DMXQSWW Phase 2 NA [63]
BNT111 DMBTGNN Phase 2 Vaccine [64]
BVD-523 DMNB4XK Phase 2 NA [65]
Cancer vaccine DM03BGT Phase 2 NA [66]
CB-10-01 DM2IFYZ Phase 2 Vaccine [67]
Coxsackievirus A21 DM2K5VP Phase 2 NA [68]
CYT-004-MelQbG10 DM6WG6C Phase 2 NA [69]
Dorgenmeltucel-L DMUUVAA Phase 2 NA [70]
E7016 DMAHGKE Phase 2 Small molecular drug [71]
EDP-1503 DMLB64C Phase 2 Live biotherapeutic product [72]
FANG vaccine DM0OV22 Phase 2 Vaccine [49]
GCAN 101 DMESDH4 Phase 2 NA [73]
Gp100:209-217(210M) peptide vaccine DM38ARE Phase 2 Vaccine [74]
GR-MD-02 DM9QF65 Phase 2 Protein [75]
GRN 1201 DMEF5UT Phase 2 Vaccine [76]
GRN-1201 DMXOYIH Phase 2 NA [68]
GSK-2302025A DMTXR77 Phase 2 NA [77]
GSK3377794 DMQ4RWW Phase 2 NA [4]
HF10 DMG5146 Phase 2 Oncolytic virus therapy [4]
Hi-8 PrimeBoost therapeutic melanoma vaccine DM2T2E8 Phase 2 NA [78]
Hi8 melanoma vaccine DMHGPZ8 Phase 2 NA [79]
Interleukin-12 gene therapy DMPO5IC Phase 2 NA [80]
IPI-549 DMG5Q7F Phase 2 NA [4]
ITIL-168 DMO3WV0 Phase 2 Cell therapy [81]
Leuvectin DM5LQEI Phase 2 NA [82]
Lifileucel DM240TX Phase 2 Cell therapy [83]
LN-144 DMQ55RL Phase 2 NA [68]
MAGE-3-transduced autologous T-cell vaccine DMFPSXI Phase 2 NA [84]
MGCD-0103 DM726HX Phase 2 Small molecular drug [3]
MKC-1106-MT DMXKOW6 Phase 2 NA [85]
MLN2480 DMBR8NF Phase 2 Small molecular drug [86]
MORAb-004 DMGK1JE Phase 2 NA [87]
mRNA-4157 DMVTTBZ Phase 2 Vaccine [88]
MSB0010445 DMICG0N Phase 2 NA [89]
Multi-epitope tyrosinase/gp100 vaccine DMN68ZL Phase 2 Vaccine [90]
Ontuxizumab DM0FJIE Phase 2 Antibody [68]
PF-4878691 DM24I0N Phase 2 NA [91]
PLX8394 DMRTD7I Phase 2 NA [92]
Polynoma-1 DM3QDA6 Phase 2 Vaccine [93]
PVSRIPO DM3ZLTB Phase 2 Vaccine [94]
RAF265 DMC56T4 Phase 2 Small molecular drug [95]
Resimmune DMT5QSD Phase 2 NA [96]
SentoClone DMHBGI0 Phase 2 NA [97]
Stage IV melanoma vaccine DMUXTV9 Phase 2 NA [98]
Tavokinogene telseplasmid DMZX0VF Phase 2 Gene therapy [4]
Telomelysin DMNNDMA Phase 2 NA [68]
TH-302 DMFU0JY Phase 2 Small molecular drug [4]
TLPLDC DMYENTG Phase 2 NA [99]
Tumor infiltrating lymphocyte DM2MQ1P Phase 2 NA [100]
Urelumab DM6RTVG Phase 2 NA [101]
V937 DMHITIP Phase 2 Vaccine [102]
Voyager-V1 DMNUDO0 Phase 2 Oncolytic virus therapy [103]
Ad-IL-12 DNA therapeutic DMB19IO Phase 1/2 NA [104]
Antigen-specific melanoma vaccine DMLFYBB Phase 1/2 NA [105]
AU-011 DMAT7SD Phase 1/2 NA [4]
Delolimogene mupadenorepvec DM4RCZ7 Phase 1/2 Oncolytic virus [106]
ENB003 DMK2B3S Phase 1/2 Small molecule [107]
HL-085 DMJDVCW Phase 1/2 NA [108]
IMCnyeso DMWVI0O Phase 1/2 NA [3]
ImmuFact IMP321 DMRKISI Phase 1/2 NA [109]
ImmunoVEX-timelan DMQWEJ5 Phase 1/2 NA [110]
LAG525 DMQX5SN Phase 1/2 NA [4]
LXS196 DM65MEL Phase 1/2 NA [4]
MAGE-A10 TCR DM6H3YS Phase 1/2 NA [3]
NCI-4650 DM04U2E Phase 1/2 NA [3]
NKTR-262 DMYR8LF Phase 1/2 NA [3]
NY-ESO-TCR DMS0L6J Phase 1/2 NA [68]
ONCOS-102 DMACFVN Phase 1/2 Oncolytic virus therapy [68]
SCIB-1 DMJQVB4 Phase 1/2 NA [111]
TRX-518 DMQS5DY Phase 1/2 Antibody [112]
Adoptive T-cell therapy DMCJHES Phase 1 NA [113]
ADP-A2M10 DM8BOFB Phase 1 CAR-T cell therapy [114]
AE-08 DM7X2HK Phase 1 Vaccine [115]
AEB701 DM8I4G0 Phase 1 NA [116]
AMEP DMFELMQ Phase 1 Small molecular drug [117]
AT13387 DM2B9E0 Phase 1 Small molecular drug [118]
Autologous T Cells Expressing MET scFv CAR DMZ763A Phase 1 CAR T Cell Therapy [119]
AV-MEL-1 DMIM8UD Phase 1 Vaccine [120]
BETULINIC ACID DMBUI2A Phase 1 Small molecular drug [121]
CAR-T cells recognizing EpCAM DMC7Y5F Phase 1 CAR T Cell Therapy [122]
CDX-1140 DMUGN0J Phase 1 Antibody [123]
CMP-001 DMGMI8P Phase 1 NA [3]
CV8102 DMYD37G Phase 1 NA [124]
DC-IL-12 DNA therapeutic DMTBBHN Phase 1 NA [125]
DEDN-6526A DMRJMDG Phase 1 NA [126]
Dendritic cancer cell vaccine DMP7JBR Phase 1 NA [127]
Flanvotumab DM2SALJ Phase 1 Antibody [128]
GEN-011 DMNELKW Phase 1 Cell therapy [129]
GPA-TriMAR-T cells DM2MILF Phase 1 CAR T Cell Therapy [130]
GSK-2241658A DM5VS7B Phase 1 Vaccine [131]
ICON-1 DM5JCNQ Phase 1 NA [68]
IL-2 pDNA DM9Y9TT Phase 1 NA [132]
INCAGN2385 DMDSZNC Phase 1 Antibody [133]
INXN 2001 DMCJ2NW Phase 1 NA [134]
Ioflubenzamide (131I) DM1DVXB Phase 1 NA [135]
Lipovaxin-MM DM3WOFK Phase 1 NA [136]
LV305 DMP0TQA Phase 1 NA [137]
Melanoma DNA vaccine DMR570I Phase 1 NA [138]
Multipeptide vaccine combination DM11P6J Phase 1 NA [139]
NEO-PV-01 DM1C6CO Phase 1 NA [3]
PF-07284890 DMK7XYH Phase 1 Small molecule [140]
PRAME antigen-specific cancer immunotherapeutic DMXRJ1N Phase 1 NA [141]
PRT1419 DMIKE0O Phase 1 Small molecular drug [142]
PTI-188 DMVK5W5 Phase 1 NA [143]
SAM-6 DMDHQYA Phase 1 Antibody [144]
SB 11285 DMZ9YWG Phase 1 NA [145]
SX-682 DMHMG6X Phase 1 Small molecular drug [146]
TAK-202 DMVYEFZ Phase 1 NA [68]
TBX-3400 DMKH7QV Phase 1 Cell therapy [147]
TTI-621 DMDNPAV Phase 1 Recombinant protein [3]
Vaccimel DM1QGVS Phase 1 NA [148]
VCL-1M01 DMS9EKG Phase 1 NA [149]
XmAb20717 DMJIH83 Phase 1 Antibody [150]
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⏷ Show the Full List of 161 Drug(s)
This Disease is Treated as An Indication in 20 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Nuleusin DMMDY27 Discontinued in Phase 3 NA [151]
AN-9 DMGL0Q2 Discontinued in Phase 2 Small molecular drug [152]
BIWB-1 DMQ6CYE Discontinued in Phase 2 Vaccine [153]
Ecromeximab DM1N060 Discontinued in Phase 2 Monoclonal antibody [154]
IDD-3 DMR6CTG Discontinued in Phase 2 NA [155]
Melanoma vaccine (ALVAC) DM3HIQY Discontinued in Phase 2 Vaccine [156]
Melaxin DM79LN9 Discontinued in Phase 2 NA [157]
TriGem DMAAITM Discontinued in Phase 2 NA [158]
XomaZyme-Mel DMQ3EUK Discontinued in Phase 2 NA [159]
Zeniplatin DMT48CI Discontinued in Phase 2 Small molecular drug [160]
ODC-0501 DMO3G2M Discontinued in Phase 1/2 NA [161]
ABX-MA1 DMZYVPB Discontinued in Phase 1 Antibody [162]
F-50040 DMMG6W5 Discontinued in Phase 1 NA [163]
RG-7256 DM0LXBW Discontinued in Phase 1 NA [164]
RG7636 DMJ2TSR Discontinued in Phase 1 NA [165]
DISC GM-CSF DMNQDTH Terminated NA [167]
Novovac-M1 DM7L3AR Terminated NA [168]
RAAV vaccine DM6FSJG Terminated NA [169]
SBP-002 DM9F7R0 Terminated NA [170]
Withaferin A DMGHLG5 Terminated Small molecular drug [171]
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⏷ Show the Full List of 20 Drug(s)
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ANAVEX 1007 DM2U16Z Preclinical NA [166]
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This Disease is Treated as An Indication in 28 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
1,3-bis(1,3-benzothiazol-2-ylthio)acetone DMP86R3 Investigative Small molecular drug [172]
111In-labeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone peptide (melanoma), NuView/University of New Mexico DMH1R1B Investigative NA [173]
20D75 DMTFJ1L Investigative NA [173]
3-benzofuran-2-yl-2-benzothiazol-2-yl-3-oxo-propanenitrile DMWLIK1 Investigative NA [172]
5-fluoro-1H-indole-2-carboxylic acid DM9U1HV Investigative Small molecular drug [172]
ADS-NPTMZ-1 DM79MNG Investigative NA [173]
AEZS-120 DMF44MM Investigative NA [173]
BCL-005 DML84IX Investigative NA [173]
Box-5 DMSCA66 Investigative NA [173]
CGEN-791 DMMJ3Q5 Investigative NA [173]
Ektomun DM63S8J Investigative NA [173]
IMX-MEL1 DMPWYPZ Investigative NA [173]
LG-723 DM6E1LB Investigative NA [173]
Lm Melanoma DMLD5HR Investigative NA [173]
Lovaxin M DME54PW Investigative NA [173]
LY-1-100 DMT8R84 Investigative NA [173]
MT-062 DM5PD0G Investigative NA [174]
MTI-SAM3 DMZUMSG Investigative NA [173]
Narciclasine DMI7A6R Investigative Small molecular drug [175]
NVX-412 DM4QUDK Investigative NA [173]
OP-03 DMXFJZ4 Investigative NA [173]
PDS-0102 DMICOMO Investigative NA [173]
PRAME-SLP DM2IS39 Investigative NA [173]
SMT-C2100 DMH8CEP Investigative NA [173]
TOCA-621 DMFXRSI Investigative NA [173]
TriMixDC DML3OYH Investigative Vaccine [176]
VitiGam DMWK5O6 Investigative NA [173]
VLD-631 DMZ4OB2 Investigative NA [173]
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⏷ Show the Full List of 28 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 864 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCA1 TTJW1GN Limited Biomarker [180]
ABCC1 TTOI92F Limited Altered Expression [181]
ABCG1 TTMWDGU Limited Biomarker [182]
ACVRL1 TTGYPTC Limited Biomarker [183]
ADAM9 TTTYQNS Limited Genetic Variation [184]
ADH7 TT3LE7P Limited Biomarker [185]
ADRA1D TT34BHT Limited Biomarker [186]
ADRB3 TTMXGCW Limited Biomarker [187]
ALOX15 TTN9T81 Limited Biomarker [188]
ALPI TTHYMUV Limited Biomarker [189]
ANGPTL4 TTWALY5 Limited Biomarker [190]
ANXA5 TT2Z83I Limited Altered Expression [191]
AQP1 TTSF1KH Limited Biomarker [192]
AQP9 TTQEI32 Limited Altered Expression [193]
ARSB TTESQTG Limited Altered Expression [194]
ATF4 TTQCKWT Limited Altered Expression [195]
ATR TT8ZYBQ Limited Genetic Variation [196]
BAGE TTS5GLJ Limited Biomarker [197]
BCL2L1 TTRE6AX Limited Altered Expression [198]
BCL2L2 TTQ79W8 Limited Biomarker [199]
BGN TT0JPVF Limited Biomarker [200]
BMP1 TT0L58T Limited Biomarker [201]
BMPR2 TTGKF90 Limited Altered Expression [202]
CA9 TT2LVK8 Limited Biomarker [203]
CALR TTUZ7OA Limited Biomarker [204]
CASP1 TTCQIBE Limited Altered Expression [205]
CASP4 TT6KIOT Limited Biomarker [206]
CASP8 TT6SZNG Limited Genetic Variation [207]
CCL21 TTLZK1U Limited Biomarker [208]
CCN1 TTPK79J Limited Biomarker [209]
CCNB1 TT9P6OW Limited Biomarker [210]
CCND3 TT1JXNR Limited Altered Expression [211]
CCR4 TT7HQD0 Limited Biomarker [212]
CCR5 TTJIH8Q Limited Altered Expression [213]
CCR7 TT2GIDQ Limited Altered Expression [214]
CD19 TTW640A Limited Biomarker [215]
CD22 TTM6QSK Limited Biomarker [216]
CD24 TTCTYNP Limited Biomarker [217]
CD27 TTDO1MV Limited Biomarker [218]
CD40LG TTIJP3Q Limited Biomarker [219]
CD6 TTMF6KC Limited Genetic Variation [220]
CD74 TTCMYP9 Limited Altered Expression [221]
CD83 TTT9MRQ Limited Altered Expression [222]
CD9 TTZEIBV Limited Altered Expression [223]
CDH5 TTXLCFO Limited Altered Expression [224]
CDK1 TTH6V3D Limited Biomarker [225]
CDK7 TTQYF7G Limited Altered Expression [226]
CDKL1 TTBTI6P Limited Altered Expression [227]
CEACAM5 TTY6DTE Limited Biomarker [228]
CFLAR TTJZQYH Limited Biomarker [229]
CHRM3 TTQ13Z5 Limited Biomarker [230]
CMA1 TT8VUE0 Limited Biomarker [231]
COASY TT4YO0Z Limited Biomarker [232]
COL18A1 TT63DI9 Limited Biomarker [233]
COL1A2 TTUABC1 Limited Altered Expression [234]
CRYZ TTP6UO8 Limited Altered Expression [235]
CSF1 TT0IQER Limited Biomarker [236]
CTSB TTF2LRI Limited Biomarker [237]
CTSD TTPT2QI Limited Biomarker [238]
CTSK TTDZN01 Limited Altered Expression [239]
CTSL TT36ETB Limited Biomarker [238]
CXCR1 TTMWT8Z Limited Biomarker [240]
CXCR2 TT30C9G Limited Altered Expression [241]
CYSLTR2 TT0PZR5 Limited Genetic Variation [242]
DHFR TTYZVDJ Limited Biomarker [243]
DHODH TTLVP78 Limited Biomarker [244]
DKK1 TTE3RAC Limited Biomarker [245]
DLK1 TTF4AVB Limited Altered Expression [246]
DOT1L TTSZ8T1 Limited Genetic Variation [247]
DPP4 TTDIGC1 Limited Biomarker [248]
DTL TT8396I Limited Biomarker [249]
DUSP1 TTG8HIM Limited Altered Expression [250]
EIF2AK3 TT79U1M Limited Genetic Variation [251]
EIF2AK4 TT9U4EP Limited Biomarker [252]
ELAVL1 TTPC9D0 Limited Altered Expression [253]
ENPEP TT9PBIL Limited Biomarker [254]
EPAS1 TTWPA54 Limited Biomarker [255]
EPHA3 TTHS2LR Limited Biomarker [256]
EPO TTQG4NR Limited Biomarker [257]
ERN1 TTKIAT3 Limited Biomarker [258]
ESRRA TTPNQAC Limited Biomarker [259]
EZR TTE47YC Limited Biomarker [260]
F2RL2 TTVSEBF Limited Biomarker [261]
FANCA TTV5HJS Limited Biomarker [262]
FASN TT7AOUD Limited Biomarker [263]
FBXW7 TT29KY7 Limited Biomarker [264]
FES TTLBY21 Limited Biomarker [265]
FFAR1 TTB8FUC Limited Biomarker [266]
FFAR4 TT08JVB Limited Altered Expression [267]
FGF1 TTMY81X Limited Biomarker [268]
FOSL1 TTY8LZG Limited Altered Expression [269]
FOXQ1 TTEJZOL Limited Biomarker [270]
FPR1 TT5Y4EM Limited Biomarker [271]
FSCN1 TTTRS9B Limited Biomarker [272]
FZD7 TTUQMO5 Limited Biomarker [273]
GH1 TTT3YKH Limited Biomarker [274]
GHR TTHJWYD Limited Biomarker [274]
GLB1 TTNGJPH Limited Altered Expression [275]
GNA11 TTSRXJW Limited Genetic Variation [276]
GNRH1 TT0ID4A Limited Altered Expression [277]
GOT1 TTU507L Limited Biomarker [278]
GPC3 TTJTSX4 Limited Altered Expression [279]
GPNMB TT7315J Limited Altered Expression [280]
GRN TT0LWE3 Limited Biomarker [281]
GSN TTUH7OM Limited Biomarker [282]
GSR TTEP6RV Limited Biomarker [283]
GZMB TTKEPHX Limited Altered Expression [284]
HDAC2 TTSHTOI Limited Biomarker [285]
HDAC3 TT4YWTO Limited Biomarker [286]
HDC TTV9GOF Limited Biomarker [287]
HEXIM1 TTFOKAH Limited Altered Expression [288]
HLA-DQA1 TTU2I3J Limited Biomarker [289]
HRAS TT28ZON Limited Genetic Variation [290]
HSD11B1 TTN7BL9 Limited Biomarker [291]
HSD11B2 TT9H85R Limited Biomarker [292]
HSF1 TTN6STZ Limited Biomarker [293]
HSPA8 TTMQL3K Limited Altered Expression [294]
HSPA9 TTMTPG3 Limited Altered Expression [295]
HSPB3 TTLH8WG Limited Biomarker [296]
HSPB8 TTY0OJN Limited Biomarker [297]
HSPG2 TT5UM29 Limited Biomarker [298]
IAPP TTHN8EM Limited Biomarker [189]
ICOS TTE5VP6 Limited Altered Expression [299]
ID1 TTBXVDE Limited Altered Expression [300]
IDUA TT0IUKX Limited Biomarker [301]
IFNAR1 TTSYFMA Limited Biomarker [302]
IFNL1 TTM624L Limited Biomarker [303]
IGFBP3 TTZHNQA Limited Biomarker [304]
IGFBP7 TTUQ01B Limited Altered Expression [269]
IKBKB TTJ3E9X Limited Biomarker [305]
IL13RA2 TTMPZ7V Limited Biomarker [306]
IL2RB TT9721Y Limited Biomarker [307]
IL32 TTD4G7L Limited Biomarker [308]
IL4R TTDWHC3 Limited Biomarker [309]
IL9 TT0JTFD Limited Biomarker [310]
INHBA TTVB30D Limited Altered Expression [311]
IRF1 TT4TU3L Limited Altered Expression [312]
IRF3 TTYR7OH Limited Altered Expression [313]
ITGA4 TTJMF9P Limited Biomarker [314]
ITGA6 TT165T3 Limited Genetic Variation [315]
ITGAE TTH0Z37 Limited Biomarker [316]
ITGB2 TTIJWR7 Limited Biomarker [317]
JAK1 TT6DM01 Limited Biomarker [318]
KCNN3 TT9JH25 Limited Biomarker [319]
KDM5C TT94UCF Limited Biomarker [320]
KDM6B TTDIJUQ Limited Altered Expression [321]
KEAP1 TT3Z6Y9 Limited Biomarker [322]
KHDRBS1 TTAT6C7 Limited Biomarker [323]
KLK3 TTS78AZ Limited Altered Expression [324]
KLK7 TTE6GTB Limited Biomarker [325]
KLRC1 TTC4IMS Limited Biomarker [326]
KMT5A TTGC95K Limited Biomarker [249]
LAG3 TTNVXAW Limited Biomarker [327]
LAMB3 TT2WOUQ Limited Biomarker [184]
LCK TT860QF Limited Biomarker [328]
LGMN TTPTWV5 Limited Altered Expression [329]
LIF TTGZ5WN Limited Biomarker [330]
LIPA TTS8T1M Limited Biomarker [331]
LPAR3 TTE2YJR Limited Altered Expression [332]
LPAR5 TTABCJ6 Limited Altered Expression [333]
LTF TTSZDQU Limited Altered Expression [334]
MAGEA10 TT1VNVM Limited Biomarker [335]
MAGEA4 TT9EQUY Limited Biomarker [335]
MAGEA6 TTJIWMO Limited Biomarker [336]
MAGEC2 TTKGUEB Limited Biomarker [337]
MALT1 TTCI81G Limited Biomarker [338]
MAP2K1 TTIDAPM Limited Genetic Variation [339]
MAP3K14 TT4LIAC Limited Biomarker [340]
MAP3K7 TTJQT60 Limited Altered Expression [341]
MAP3K8 TTGECUM Limited Genetic Variation [342]
MARK2 TTAJ45Y Limited Biomarker [343]
MBTPS1 TTNSM2I Limited Biomarker [344]
MDK TTV8UE7 Limited Biomarker [345]
MELK TTBZOTY Limited Biomarker [346]
MERTK TTO7LKR Limited Biomarker [347]
MGLL TTZ963I Limited Altered Expression [348]
MRC1 TTKV8W5 Limited Altered Expression [349]
MTA1 TTO4HUS Limited Biomarker [350]
MTDH TTH6SA5 Limited Biomarker [351]
MYH2 TTBIL13 Limited Altered Expression [352]
NACC1 TT4AQ5F Limited Altered Expression [353]
NCOA3 TT124R0 Limited Biomarker [354]
NCR1 TTQNRJM Limited Biomarker [355]
NEDD8 TTNDC4K Limited Biomarker [356]
NEK2 TT3VZ24 Limited Altered Expression [357]
NFKB2 TTKLNRV Limited Biomarker [358]
NLRP1 TTQX29T Limited Genetic Variation [359]
NOTCH3 TTVX7IA Limited Biomarker [360]
NPEPPS TT371QC Limited Altered Expression [324]
NR1H2 TTXA6PH Limited Biomarker [361]
NRG1 TTEH395 Limited Biomarker [362]
NRN1 TTS05MJ Limited Biomarker [363]
NTN1 TT0AH4L Limited Biomarker [364]
NUF2 TTIXBFP Limited Biomarker [365]
OGG1 TTRU01G Limited Genetic Variation [366]
OR51E2 TTZRE3C Limited Biomarker [367]
OSM TTIVXSE Limited Altered Expression [368]
P2RY13 TT1FE3L Limited Genetic Variation [290]
P2RY4 TT24DGP Limited Biomarker [361]
PAK1 TTFN95D Limited Altered Expression [369]
PDE4A TTZ97H5 Limited Biomarker [370]
PDE4D TTSKMI8 Limited Biomarker [370]
PDGFC TTOABM9 Limited Biomarker [371]
PDGFD TTSN0GA Limited Altered Expression [372]
PDGFRA TT8FYO9 Limited Biomarker [373]
PDGFRB TTI7421 Limited Altered Expression [374]
PDXP TT9UYG4 Limited Biomarker [375]
PFKFB3 TTTHMQJ Limited Biomarker [376]
PGF TT48I1Y Limited Biomarker [377]
PHGDH TT8DRCK Limited Altered Expression [378]
PIM1 TTTN5QW Limited Biomarker [379]
PIM3 TTCGOIN Limited Biomarker [380]
PIN1 TTJNTSI Limited Biomarker [381]
PLG TTP86E2 Limited Biomarker [382]
PPARGC1B TTKSQ3W Limited Altered Expression [280]
PRDX5 TTLPJWH Limited Biomarker [375]
PRKCZ TTBSN0L Limited Biomarker [383]
PRKG1 TT7IZSA Limited Biomarker [384]
PRMT1 TTVOJAI Limited Biomarker [385]
PRMT5 TTR1D7X Limited Biomarker [386]
PSEN2 TTWN3F4 Limited Altered Expression [387]
PSIP1 TTH9LDP Limited Biomarker [307]
PSMB8 TTEAD9J Limited Biomarker [388]
PTAFR TTQL5VC Limited Biomarker [389]
PTBP1 TTWMX0U Limited Biomarker [390]
PTGES TTYLQ8V Limited Biomarker [391]
PTK7 TTXH2ZN Limited Biomarker [392]
PTN TTA9EJK Limited Altered Expression [393]
PTP4A3 TT7YM8D Limited Altered Expression [394]
RAB7A TTF6WAQ Limited Biomarker [395]
RAPGEF4 TTOS63B Limited Biomarker [396]
RECK TTRZBW7 Limited Biomarker [397]
RGS4 TTGTKX9 Limited Biomarker [398]
RICTOR TT143WL Limited Altered Expression [399]
RIPK1 TTVJHX8 Limited Biomarker [341]
RNASEL TT7V0K4 Limited Biomarker [400]
ROCK1 TTZN7RP Limited Altered Expression [401]
ROCK2 TTGWKQJ Limited Altered Expression [402]
ROS1 TTSZ6Y3 Limited Genetic Variation [403]
RPS6KA1 TTIXKA4 Limited Biomarker [404]
RPS6KB1 TTG0U4H Limited Biomarker [379]
RPSA TTLUW5B Limited Biomarker [405]
RRM1 TTWP0NS Limited Altered Expression [406]
RTN4R TTVRZUO Limited Biomarker [407]
RUNX2 TTD6SZ8 Limited Biomarker [408]
S100A8 TT4AF6N Limited Biomarker [409]
SDC2 TT5H2F0 Limited Altered Expression [410]
SDHD TTVH9W8 Limited Altered Expression [411]
SELE TT1PL7M Limited Altered Expression [412]
SELPLG TTS5K8U Limited Biomarker [413]
SEMA4D TT5UT28 Limited Biomarker [414]
SERPINB3 TT6QLPX Limited Genetic Variation [415]
SERPINB5 TT1KW50 Limited Altered Expression [416]
SETD2 TTPC3H4 Limited Biomarker [417]
SLC16A1 TTN1J82 Limited Genetic Variation [418]
SLC1A5 TTF7WRM Limited Biomarker [419]
SLC5A2 TTF8JAT Limited Biomarker [420]
SMAD7 TT0J32Z Limited Biomarker [421]
SOX5 TTXHSZK Limited Altered Expression [422]
SQSTM1 TTOT2RY Limited Biomarker [323]
STC1 TTDLUER Limited Biomarker [321]
SUV39H1 TTUWQTK Limited Biomarker [423]
TCF3 TTULOD8 Limited Biomarker [307]
TEK TT9VGXW Limited Altered Expression [424]
TFPI TT068JH Limited Biomarker [425]
TFRC TT8MG4S Limited Biomarker [426]
TGFA TTTLQFR Limited Altered Expression [427]
TLR8 TT8CWFK Limited Altered Expression [428]
TMSB4X TTMVAIU Limited Biomarker [429]
TNFRSF1B TT63WSF Limited Biomarker [307]
TNFSF4 TTBW580 Limited Altered Expression [430]
TOP2A TTCGY2K Limited Altered Expression [406]
TPCN2 TTHQJ2Y Limited Biomarker [431]
TPT1 TT3PTB6 Limited Altered Expression [432]
TRAF6 TTCDR6M Limited Biomarker [433]
TREM2 TTQRMSJ Limited Altered Expression [434]
TRPC3 TTNVC34 Limited Altered Expression [435]
TRPM8 TTXDKTO Limited Altered Expression [436]
TYRO3 TTIEMFN Limited Biomarker [437]
UCHL1 TTX9IFP Limited Altered Expression [438]
USP13 TTVJIO2 Limited Biomarker [439]
USP5 TTGYTMA Limited Biomarker [440]
USP7 TTXU3EQ Limited Biomarker [441]
USP8 TT1J07C Limited Altered Expression [442]
UTRN TTNO1VA Limited Biomarker [443]
VCP TTHNLSB Limited Biomarker [444]
VSIR TT51SK8 Limited Biomarker [445]
XRCC5 TTCB9KW Limited Biomarker [446]
ZEB2 TTT2WK4 Limited Altered Expression [447]
ADRB2 TTG8ZWP Disputed Altered Expression [448]
AICDA TTKRTP6 Disputed Biomarker [413]
ARAF TT5TURO Disputed Biomarker [449]
ATG7 TTLVB9Z Disputed Biomarker [450]
BBC3 TT7JUKC Disputed Biomarker [451]
BRS3 TTKYEPM Disputed Altered Expression [452]
CD248 TTYJWT7 Disputed Altered Expression [453]
CD28 TTQ13FT Disputed Biomarker [454]
CD40 TT1ERKL Disputed Biomarker [455]
CD86 TT53XHB Disputed Altered Expression [456]
CDK8 TTBJR4L Disputed Biomarker [457]
CDKN2C TTBRUGA Disputed Genetic Variation [458]
CREB1 TTH4AN3 Disputed Biomarker [459]
CXCR3 TT1UCIJ Disputed Biomarker [460]
DDX58 TTVB0O3 Disputed Biomarker [461]
DICER1 TTTEOPU Disputed Altered Expression [462]
EPCAM TTZ8WH4 Disputed Biomarker [463]
EPHB6 TTZEMUY Disputed Biomarker [464]
FGF4 TTCEKVZ Disputed Biomarker [465]
FOXM1 TTD3KOX Disputed Biomarker [466]
FUT4 TTNV1KZ Disputed Biomarker [467]
GEM TTAZF9M Disputed Genetic Variation [468]
HDAC1 TT6R7JZ Disputed Biomarker [469]
HSP90B1 TTFPKXQ Disputed Altered Expression [470]
KCNK9 TTL4FMB Disputed Altered Expression [471]
LPAR2 TTB7Y8I Disputed Altered Expression [452]
LRP1 TTF2V7I Disputed Biomarker [472]
MMP13 TTHY57M Disputed Altered Expression [473]
MYB TT8V13P Disputed Biomarker [474]
NOTCH4 TTXDIK2 Disputed Biomarker [475]
NUAK2 TTHVOTQ Disputed Altered Expression [476]
PPARA TTJ584C Disputed Biomarker [477]
PTK2 TTON5IT Disputed Biomarker [478]
RALBP1 TTVSRUA Disputed Biomarker [479]
ROR1 TTDEJAU Disputed Altered Expression [480]
ROR2 TTUDPCI Disputed Altered Expression [480]
RUNX3 TTKCVO7 Disputed Altered Expression [481]
SIK1 TT1H6LC Disputed Altered Expression [482]
SLC1A2 TT2F078 Disputed Biomarker [450]
SLC22A16 TTITAVR Disputed Altered Expression [483]
SMPD1 TTJTM88 Disputed Biomarker [484]
SNCA TT08OSU Disputed Biomarker [485]
SOCS3 TTI0ME6 Disputed Biomarker [486]
SP1 TTZEP6S Disputed Genetic Variation [487]
SSTR4 TTAE1BR Disputed Altered Expression [452]
TERF1 TT1Y6J2 Disputed Genetic Variation [488]
TIE1 TTT4236 Disputed Genetic Variation [489]
TLR7 TTRJ1K4 Disputed Biomarker [490]
TNFRSF10A TT5WLRX Disputed Altered Expression [491]
TNFRSF10B TTW20TU Disputed Biomarker [492]
TPX2 TT0PHL4 Disputed Biomarker [493]
TRPM2 TTEBMN7 Disputed Biomarker [494]
TWIST1 TTX1MY7 Disputed Altered Expression [269]
ABCC2 TTFLHJV moderate Altered Expression [495]
ADORA2A TTM2AOE moderate Biomarker [496]
ADORA2B TTNE7KG moderate Altered Expression [497]
AMACR TTLN1AP moderate Biomarker [498]
ANG TTURHFP moderate Biomarker [499]
CASP2 TT12VNG moderate Altered Expression [500]
CBS TTVZJ7G moderate Biomarker [501]
CCL11 TTCF05Y moderate Biomarker [502]
CCR9 TTIPS8B moderate Altered Expression [503]
CD160 TTOFEAS moderate Altered Expression [504]
CD200 TT0BE68 moderate Altered Expression [505]
CD59 TTBGTEJ moderate Altered Expression [506]
CDH11 TTRGWZC moderate Posttranslational Modification [507]
CDH3 TTARMD9 moderate Altered Expression [508]
CHUK TT1F8OQ moderate Biomarker [509]
CRTC1 TT4GO0F moderate Altered Expression [510]
CSF3R TTC70AJ moderate Biomarker [511]
CSNK2A1 TTER6YH moderate Biomarker [512]
DIABLO TTN74LE moderate Biomarker [513]
EIF2AK2 TTXEZJ4 moderate Altered Expression [514]
EIF5A2 TTH53G9 moderate Altered Expression [515]
EPHA1 TTLFZVU moderate Biomarker [516]
F2RL3 TTD0652 moderate Biomarker [517]
F9 TTFEZ5Q moderate Genetic Variation [518]
FAP TTGPQ0F moderate Biomarker [519]
FCGR2B TT5RWKQ moderate Biomarker [520]
FGFR4 TT1KX2S moderate Biomarker [521]
FPR2 TTOJ1NF moderate Biomarker [522]
GABRA3 TT37EDJ moderate Biomarker [523]
GHRHR TTG4R8V moderate Biomarker [524]
GNRHR TT8R70G moderate Biomarker [525]
GRIK4 TTQV6BO moderate Biomarker [526]
GSTO1 TTWO3SH moderate Altered Expression [527]
HDAC11 TT8K17W moderate Altered Expression [514]
HDGF TTKGV26 moderate Altered Expression [528]
HGFAC TTD96RW moderate Biomarker [529]
HOXB13 TTZ6I58 moderate Biomarker [530]
HTRA1 TT8POQR moderate Altered Expression [531]
IL23A TTC1GLB moderate Biomarker [532]
INPP5D TTTP2Z1 moderate Altered Expression [533]
ISG15 TTVOH3T moderate Altered Expression [534]
ITGA2 TTSJ542 moderate Genetic Variation [315]
ITGAL TT48WR6 moderate Biomarker [317]
KCNH5 TTX8LQ0 moderate Altered Expression [535]
KDM4A TTZHPB8 moderate Biomarker [536]
KDM4C TTV8CRH moderate Biomarker [536]
KIR2DL1 TT4UXPE moderate Genetic Variation [468]
KIR2DL3 TTEX3SI moderate Biomarker [468]
KISS1R TT3KBZY moderate Biomarker [537]
LASP1 TTZJA87 moderate Altered Expression [538]
LIFR TTID542 moderate Biomarker [539]
LTA4H TTXZEAJ moderate Altered Expression [540]
MAP3K1 TTW8TJI moderate Altered Expression [541]
MMP12 TTXZ0KQ moderate Altered Expression [542]
MPL TTIHYA4 moderate Biomarker [543]
MSMB TTYH1ZK moderate Biomarker [544]
MUTYH TTNB0ZK moderate Genetic Variation [545]
MYCN TT9JBY5 moderate Altered Expression [546]
NELL1 TT7H4BF moderate Biomarker [547]
NODAL TTK2O1Q moderate Altered Expression [548]
NR4A2 TT9HKN3 moderate Biomarker [549]
NR5A2 TTAU3SY moderate Genetic Variation [550]
NUAK1 TT65FL0 moderate Biomarker [551]
ORAI1 TTE76YK moderate Biomarker [552]
PAWR TT3I4WV moderate Biomarker [517]
PCSK9 TTNIZ2B moderate Biomarker [553]
PDE1C TTW2HRK moderate Genetic Variation [554]
PDE2A TTJGW1Z moderate Altered Expression [555]
PDGFA TTSM78N moderate Altered Expression [556]
PLA2G2A TTO8QRU moderate Altered Expression [557]
PLAUR TTNOSTX moderate Altered Expression [558]
PLP2 TTK5OG6 moderate Biomarker [559]
PRKDC TTK3PY9 moderate Genetic Variation [560]
PSMD10 TT2H4LN moderate Altered Expression [527]
PTPN11 TT7WUAV moderate Biomarker [561]
RARA TTW38KT moderate Posttranslational Modification [562]
RCVRN TTDQTEY moderate Altered Expression [563]
RRM2 TT1S4LJ moderate Genetic Variation [564]
SEMA3A TTVKD3S moderate Biomarker [565]
SLC16A3 TTG6VD5 moderate Altered Expression [566]
SRPK1 TTU3WV6 moderate Biomarker [567]
TACR1 TTZPO1L moderate Altered Expression [568]
TAGLN TTDRZ9H moderate Biomarker [451]
TGFBR1 TTP4520 moderate Biomarker [569]
THBD TTAPV67 moderate Altered Expression [570]
TIAM1 TTNU6I5 moderate Biomarker [571]
TNFRSF12A TTKPS7V moderate Biomarker [572]
TNFRSF8 TT2GM5R moderate Biomarker [573]
TNFSF14 TTKVENM moderate Altered Expression [574]
TNS4 TT1K65C moderate Biomarker [575]
TOP1 TTGTQHC moderate Biomarker [576]
TRIM24 TT9Q7AE moderate Genetic Variation [577]
TRIM27 TTTO3QN moderate Biomarker [522]
TXNRD1 TTR7UJ3 moderate Biomarker [578]
VDAC1 TTAMKGB moderate Biomarker [579]
XPA TTGT87E moderate Biomarker [580]
XPO1 TTCJUR4 moderate Biomarker [581]
ABL1 TT6B75U Strong Biomarker [582]
ACKR3 TTRQJTC Strong Altered Expression [452]
ACVR1 TTJNBQA Strong Genetic Variation [583]
AGER TTMO9HF Strong Biomarker [584]
AGRP TT4DE1O Strong Biomarker [585]
AHR TT037IE Strong Genetic Variation [586]
AIMP2 TTXWHGF Strong Biomarker [587]
AKT3 TTO6SGY Strong Biomarker [588]
ALCAM TT2AFT6 Strong Biomarker [589]
ALK TTPMQSO Strong Genetic Variation [590]
ALOX12 TT12ABZ Strong Biomarker [591]
AOC3 TT7HC21 Strong Altered Expression [592]
APEX1 TTHGL48 Strong Altered Expression [593]
APOH TT2OUI9 Strong Biomarker [594]
AQP3 TTLDNMQ Strong Biomarker [595]
ARL2 TTIDSFT Strong Biomarker [285]
ATM TTKBM7V Strong Altered Expression [596]
ATRAID TTFLIKM Strong Biomarker [597]
AURKA TTPS3C0 Strong Biomarker [598]
AURKB TT9RTBL Strong Altered Expression [599]
AXL TTZPY6J Strong Biomarker [600]
B2M TTY7FKA Strong Biomarker [601]
BAK1 TTFM7V0 Strong Biomarker [602]
BCL6 TTC9YX5 Strong Biomarker [450]
BIRC2 TTQ5LRD Strong Biomarker [603]
BIRC7 TTHZ8TA Strong Biomarker [604]
BMP6 TT07RIB Strong Biomarker [605]
BRIP1 TTZV7LJ Strong Genetic Variation [606]
BST2 TT90BJT Strong Altered Expression [607]
C1QB TT8A9DM Strong Biomarker [608]
C9orf72 TTA4SHR Strong Genetic Variation [609]
CA13 TTQPHSR Strong Biomarker [610]
CA2 TTANPDJ Strong Biomarker [611]
CAPN1 TT1WBIJ Strong Biomarker [612]
CASP10 TTX5HEK Strong Biomarker [613]
CASP6 TTKW4ML Strong Biomarker [614]
CASP7 TTM7Y45 Strong Biomarker [615]
CBX7 TTBN3HC Strong Altered Expression [616]
CCKBR TTVFO0U Strong Biomarker [617]
CCL5 TT9DWLC Strong Altered Expression [618]
CD163 TTTZ9DE Strong Altered Expression [619]
CD44 TTWFBT7 Strong Biomarker [620]
CDC7 TTSMTDI Strong Altered Expression [621]
CDCA8 TT04YCM Strong Altered Expression [622]
CDH2 TT1WS0T Strong Altered Expression [623]
CDK11B TT5Q79O Strong Biomarker [624]
CDK13 TTRIM0E Strong Biomarker [625]
CDK6 TTO0FDJ Strong Biomarker [626]
CDKN1C TTBSUAR Strong Biomarker [530]
CEACAM3 TTPX7I5 Strong Biomarker [228]
CFB TTA0P7K Strong Biomarker [627]
CGA TTFC29G Strong Genetic Variation [628]
CHEK1 TTTU902 Strong Biomarker [629]
CLN3 TTORF9W Strong Altered Expression [630]
CLU TTRL76H Strong Therapeutic [631]
COL7A1 TTBCOKN Strong Biomarker [632]
COPS5 TTSTNJR Strong Altered Expression [633]
CR1 TTEA8OW Strong Altered Expression [634]
CRK TTFEUYR Strong Biomarker [587]
CRY1 TT5MLZR Strong Biomarker [635]
CSF2 TTNYZG2 Strong Biomarker [636]
CSK TTX6F0Q Strong Genetic Variation [637]
CSNK1A1 TTFQEMX Strong Biomarker [638]
CSPG4 TT7MYXI Strong Biomarker [639]
CTAG1A TTE5ITK Strong Altered Expression [640]
CTCFL TTY0RZT Strong Altered Expression [641]
CTH TTLQUZS Strong Biomarker [501]
CUBN TT9YLCR Strong Biomarker [285]
CUL3 TTPCU0Q Strong Biomarker [642]
CXCL10 TTQOVYA Strong Biomarker [643]
CXCL12 TT4UGTF Strong Biomarker [644]
CXCL2 TTZF0K2 Strong Biomarker [645]
CXCR4 TTBID49 Strong Biomarker [646]
CXXC5 TTVS4C3 Strong Altered Expression [647]
CYP1B1 TTI84H7 Strong Biomarker [530]
DDC TTN451K Strong Biomarker [648]
DDR2 TTU98HG Strong Biomarker [649]
DGKA TTGL8F0 Strong Biomarker [650]
DHCR24 TTTK0NH Strong Altered Expression [651]
DKK2 TTST5KX Strong Altered Expression [652]
DLL1 TT9CFQD Strong Genetic Variation [653]
DLL3 TT1C9K6 Strong Biomarker [654]
DNASE1 TTYWGOJ Strong Biomarker [655]
DRD1 TTZFYLI Strong Altered Expression [656]
DYRK1A TTSBVFO Strong Biomarker [657]
E2F1 TTASI04 Strong Biomarker [658]
EBP TT4VQZX Strong Altered Expression [659]
EGFL7 TT7WD0H Strong Altered Expression [660]
EGLN2 TTMHFRY Strong Biomarker [661]
EIF4E TTZGCP6 Strong Biomarker [195]
ENPP1 TTZTIWS Strong Biomarker [662]
ENTPD1 TTYM8DJ Strong Biomarker [663]
EP300 TTGH73N Strong Altered Expression [466]
EPHA4 TTG84D3 Strong Altered Expression [664]
EPHB2 TTKPV6O Strong Genetic Variation [665]
EPOR TTAUX24 Strong Biomarker [666]
ERAP1 TT60XFL Strong Biomarker [667]
ETS1 TTTGPSD Strong Altered Expression [668]
F10 TTCIHJA Strong Biomarker [669]
F2R TTL935N Strong Altered Expression [670]
F2RL1 TTQR74A Strong Biomarker [530]
F3 TT38MDJ Strong Altered Expression [671]
FABP3 TT3TGLR Strong Altered Expression [672]
FASLG TTO7014 Strong Genetic Variation [673]
FAT1 TTGUJYV Strong Biomarker [674]
FBXO11 TT6G10V Strong Altered Expression [675]
FCGR3A TTIFOC0 Strong Biomarker [676]
FDFT1 TTFQEO5 Strong Biomarker [677]
FGF18 TT6ICRA Strong Altered Expression [678]
FOLR2 TTT54CI Strong Altered Expression [679]
FOS TTOM5AU Strong Biomarker [680]
FOXC2 TTLBAP1 Strong Altered Expression [681]
FST TTDNM9W Strong Altered Expression [682]
GAPDH TTUGSWA Strong Altered Expression [683]
GAS6 TT69QD2 Strong Altered Expression [684]
GDF15 TT4MXVG Strong Biomarker [685]
GDNF TTF23ML Strong Altered Expression [459]
GGT1 TTZVT7O Strong Altered Expression [686]
GJB6 TTAU8SJ Strong Altered Expression [687]
GLI1 TTJOMH6 Strong Altered Expression [688]
GLI2 TT045OH Strong Altered Expression [689]
GLO1 TTV9A7R Strong Biomarker [690]
GPRC6A TTI1PRE Strong Biomarker [691]
GRIN2A TTKJEMQ Strong Genetic Variation [692]
GRM3 TT8A9EF Strong Biomarker [693]
GSK3A TTQWAU1 Strong Altered Expression [694]
HAL TTXQOZW Strong Biomarker [695]
HAX1 TT21BYA Strong Altered Expression [696]
HDAC6 TT5ZKDI Strong Biomarker [697]
HMGB2 TTA78JQ Strong Biomarker [698]
HOXA11 TTEX4ZA Strong Altered Expression [699]
HPGDS TTCYE56 Strong Biomarker [700]
HRH2 TTQHJ1K Strong Altered Expression [701]
HSP90AA1 TT78R5H Strong Biomarker [702]
HSP90AB1 TTH5YN2 Strong Biomarker [703]
HSPA5 TTW26OG Strong Biomarker [704]
HTR2B TT0K1SC Strong Altered Expression [656]
ICOSLG TTB9Z8R Strong Altered Expression [705]
IDO1 TTZJYKH Strong Altered Expression [706]
IFNA2 TTSIUJ9 Strong Biomarker [707]
IFNA5 TTLHGSF Strong Therapeutic [708]
IFNB1 TT4TZ8J Strong Biomarker [709]
IFNG TT93WF5 Strong Biomarker [710]
IL12A TTRTK6Y Strong Altered Expression [711]
IL15 TTJFA35 Strong Biomarker [712]
IL15RA TTGN89I Strong Biomarker [712]
IL17D TTC5LTG Strong Biomarker [713]
IL19 TT87RWS Strong Biomarker [714]
IL2 TTF89GD Strong Altered Expression [715]
IL24 TT1EPXZ Strong Biomarker [716]
IL25 TTVMO5W Strong Biomarker [717]
IL2RA TT10Y9E Strong Genetic Variation [320]
IL7 TT8FRMO Strong Biomarker [718]
IMP3 TTEJA2R Strong Altered Expression [719]
IRAK1 TTXAJWN Strong Biomarker [720]
IRF8 TTHUBNK Strong Biomarker [721]
ITGA11 TTANXZ7 Strong Altered Expression [722]
ITGB1 TTBVIQC Strong Altered Expression [723]
ITGB3 TTJA1ZO Strong Biomarker [724]
ITK TT3C80U Strong Biomarker [725]
JUN TTS7IR5 Strong Biomarker [726]
KCNMA1 TTE87WJ Strong Altered Expression [727]
KDM1A TTNR0UQ Strong Biomarker [536]
KDM5B TTCLI75 Strong Biomarker [728]
KLRK1 TTLRN4A Strong Genetic Variation [729]
LONP1 TTM1VPZ Strong Altered Expression [730]
LOX TTQHNAM Strong Biomarker [731]
LTBR TTFO0PM Strong Biomarker [732]
LYVE1 TTG8DNU Strong Altered Expression [733]
M6PR TT95ICL Strong Altered Expression [734]
MAD1L1 TTNE9U7 Strong Biomarker [735]
MAG TT9XFON Strong Biomarker [736]
MAGEA2 TTOZT28 Strong Biomarker [737]
MAGEC1 TT9M6NA Strong Biomarker [738]
MAP2K2 TT8H9GB Strong Biomarker [739]
MAP3K5 TTOQCD8 Strong Genetic Variation [740]
MAP3K9 TTUNSIX Strong Biomarker [741]
MAPK12 TTYT93M Strong Biomarker [742]
MAPK14 TTQBR95 Strong Biomarker [587]
MAPK3 TT1MG9E Strong Altered Expression [743]
MAPK8 TT0K6EO Strong Biomarker [587]
MC4R TTD0CIQ Strong Biomarker [744]
MCHR1 TTX4RTB Strong Altered Expression [745]
MCHR2 TTS17MG Strong Genetic Variation [746]
MCL1 TTL53M6 Strong Biomarker [747]
MCM7 TT1RM3F Strong Biomarker [748]
MCOLN1 TT9XBVO Strong Biomarker [749]
MDM2 TT9TE0O Strong Biomarker [750]
MDM4 TT9OUDQ Strong Biomarker [386]
METAP2 TTZL0OI Strong Altered Expression [751]
MFGE8 TT1GLAJ Strong Biomarker [752]
MGMT TTJ8DV7 Strong Biomarker [753]
MKNK1 TTEZAUX Strong Biomarker [195]
MMP11 TTZW4MV Strong Altered Expression [754]
MMP14 TTJ4QE7 Strong Altered Expression [397]
MMP8 TTGA1IV Strong Biomarker [755]
MRGPRX1 TTIX6PK Strong Biomarker [691]
MS4A1 TTUE541 Strong Biomarker [756]
MSI1 TTSM4BA Strong Altered Expression [757]
MST1R TTBQ3OC Strong Biomarker [544]
MTAP TTDBX7N Strong Genetic Variation [758]
MTNR1B TT32JK8 Strong Altered Expression [759]
MVD TTE5J6X Strong Biomarker [760]
MYD88 TTB6Q2O Strong Altered Expression [477]
NCL TTK1V5Q Strong Biomarker [761]
NEDD4 TT1QU6G Strong Altered Expression [762]
NEDD9 TT1UREA Strong Biomarker [763]
NF2 TTZIK7P Strong Biomarker [764]
NFKB1 TTUIZKC Strong Altered Expression [477]
NGF TTDN3LF Strong Genetic Variation [765]
NQO2 TTJLP0R Strong Altered Expression [766]
NR1I3 TTRANFM Strong Biomarker [767]
NRP1 TTIPJCB Strong Altered Expression [768]
NT5E TTK0O6Y Strong Biomarker [663]
NTF3 TTZHKV9 Strong Biomarker [769]
NTF4 TTIM2WO Strong Biomarker [769]
NTRK1 TTTDVOJ Strong Biomarker [770]
OSMR TTAH0KM Strong Biomarker [771]
OXER1 TT7WBSV Strong Biomarker [691]
PAGE5 TTNWOIT Strong Altered Expression [772]
PAM TTF4ZPC Strong Biomarker [773]
PARP1 TTVDSZ0 Strong Biomarker [774]
PCSK1 TTED9LZ Strong Biomarker [662]
PCSK7 TTD30LY Strong Biomarker [775]
PDE1A TT73TEJ Strong Genetic Variation [776]
PDE4C TT6A59G Strong Biomarker [777]
PDE8A TTIS4OW Strong Biomarker [778]
PDGFB TTQA6SX Strong Biomarker [779]
PDK1 TTCZOF2 Strong Altered Expression [446]
PDPK1 TTYMGWX Strong Altered Expression [446]
PECAM1 TT4EZB2 Strong Biomarker [780]
PEPD TTLZXI0 Strong Altered Expression [781]
PGC TT7K6AD Strong Altered Expression [782]
PIGU TT2LHI6 Strong Genetic Variation [783]
PKMYT1 TTB4PAZ Strong Biomarker [285]
PLD1 TT3T17P Strong Altered Expression [784]
PLEKHA5 TTCDZMO Strong Biomarker [785]
PMS1 TTX1ISF Strong Altered Expression [786]
POMC TT21AKM Strong Biomarker [787]
POSTN TT8ALTZ Strong Biomarker [788]
PPARD TT2JWF6 Strong Genetic Variation [789]
PRAME TTPH7T0 Strong Biomarker [790]
PRKCA TTFJ8Q1 Strong Altered Expression [791]
PRKCB TTYPXQF Strong Altered Expression [792]
PRKCD TT7A1BO Strong Genetic Variation [793]
PRKCE TT57MT2 Strong Biomarker [794]
PRKCI TTWJTHX Strong Biomarker [795]
PRSS1 TT2WR1T Strong Biomarker [796]
PSMB6 TT8EPLT Strong Genetic Variation [653]
PTGS2 TTVKILB Strong Biomarker [797]
PTPN6 TT369M5 Strong Biomarker [798]
PYGM TTZHY6R Strong Genetic Variation [799]
QPCT TTJ7YTV Strong Biomarker [530]
RAB22A TTAJ746 Strong Biomarker [800]
RAB9A TT958S6 Strong Biomarker [801]
RAC1 TT2M9CG Strong Altered Expression [802]
RAD51 TTC0G1L Strong Biomarker [469]
RAF1 TTAN5W2 Strong Genetic Variation [803]
REG3A TTL4H8N Strong Biomarker [804]
RET TT4DXQT Strong Biomarker [706]
RHAG TTVHFE8 Strong Biomarker [805]
RHO TTH0KSX Strong Altered Expression [806]
RHOB TT6LPFO Strong Biomarker [807]
ROBO1 TTND1YP Strong Biomarker [808]
RPS6KA3 TTUM2ZR Strong Biomarker [809]
RSF1 TTMP86V Strong Altered Expression [810]
S100A9 TT0TMQG Strong Altered Expression [811]
SCT TTOBVIN Strong Biomarker [691]
SELL TT2IYXF Strong Altered Expression [812]
SERPINF1 TTR59S1 Strong Biomarker [813]
SF3B1 TTL2WUI Strong Altered Expression [814]
SHCBP1 TTZ9WGL Strong Biomarker [773]
SIRT5 TTH0IOD Strong Genetic Variation [815]
SIRT6 TTUXYWF Strong Biomarker [816]
SKP2 TT5B2EO Strong Altered Expression [817]
SLC15A2 TT27Q3A Strong Biomarker [738]
SLC17A5 TTFSUIA Strong Biomarker [393]
SLC33A1 TTL69WB Strong Altered Expression [818]
SLC38A2 TTUSC27 Strong Altered Expression [819]
SLC39A6 TTZN1CF Strong Altered Expression [820]
SLC52A2 TT6TKEN Strong Altered Expression [821]
SLC5A5 TTW7HI9 Strong Biomarker [822]
SLC6A11 TT8RXO5 Strong Biomarker [823]
SLC7A11 TTBZMIO Strong Altered Expression [824]
SLC9A1 TTGSEFH Strong Altered Expression [825]
SOCS1 TT8COJM Strong Biomarker [826]
SRC TT6PKBN Strong Biomarker [274]
SREBF1 TTER0UB Strong Genetic Variation [827]
SYK TT2HUPM Strong Biomarker [828]
TDG TTEXRQD Strong Biomarker [829]
TDGF1 TTN7HMG Strong Altered Expression [830]
TERT TTQY2EJ Strong Biomarker [831]
TF TT8WXAV Strong Altered Expression [832]
THRB TTGER3L Strong Genetic Variation [833]
TIGIT TTWNL74 Strong Altered Expression [327]
TLR1 TTW14D0 Strong Genetic Variation [834]
TLR3 TTD24Y0 Strong Biomarker [835]
TLR4 TTISGCA Strong Biomarker [477]
TNC TTUCPMY Strong Altered Expression [836]
TNF TTF8CQI Strong Altered Expression [477]
TNFRSF9 TTPW9LJ Strong Biomarker [837]
TNNC1 TT8RDXP Strong Biomarker [838]
TRH TT2Z39D Strong Biomarker [839]
TRIM59 TT613U4 Strong Biomarker [840]
TRPC1 TTA76X0 Strong Biomarker [796]
TRPM7 TTFPVZO Strong Biomarker [841]
TRPV2 TTBECWA Strong Altered Expression [842]
TTK TTP7EGM Strong Biomarker [301]
TYMP TTO0IB8 Strong Biomarker [843]
TYRP1 TTFRV98 Strong Altered Expression [844]
VEGFC TT0QUFV Strong Altered Expression [845]
VEGFD TTOM5H4 Strong Biomarker [846]
WEE1 TTJFOAL Strong Altered Expression [847]
WNT5A TTKG7F8 Strong Biomarker [750]
WRN TT2H5WQ Strong Genetic Variation [848]
XIAP TTK3WBU Strong Altered Expression [849]
YAP1 TT8UN2D Strong Biomarker [850]
ABCB1 TT3OT40 Definitive Biomarker [851]
ADA TTLP57V Definitive Biomarker [852]
ADAM17 TT6AZXG Definitive Biomarker [853]
ADRA1A TTNGILX Definitive Altered Expression [452]
ADRA2B TTWM4TY Definitive Altered Expression [452]
AGTR1 TT8DBY3 Definitive Biomarker [854]
ANPEP TTPHMWB Definitive Altered Expression [855]
ARG1 TT7ZQEV Definitive Biomarker [856]
BCL2A1 TTGT9C7 Definitive Altered Expression [747]
BDNF TTSMLOH Definitive Genetic Variation [765]
BIRC3 TTAIWZN Definitive Biomarker [857]
BMI1 TTIPNSR Definitive Biomarker [858]
BSG TT5UJWD Definitive Biomarker [433]
C5 TTKANGO Definitive Biomarker [859]
C5AR1 TTHXFA1 Definitive Biomarker [859]
CAMP TTULOB6 Definitive Biomarker [860]
CCL22 TTBTWI1 Definitive Biomarker [861]
CCL3 TT8I4WB Definitive Altered Expression [862]
CD47 TT28S46 Definitive Biomarker [863]
CD80 TT89Z17 Definitive Altered Expression [456]
CDK9 TT1LVF2 Definitive Altered Expression [864]
CDKN1A TT9GUW0 Definitive Biomarker [865]
CMKLR1 TT4UGZL Definitive Biomarker [866]
CSF1R TT7MRDV Definitive Biomarker [455]
CTSS TTUMQVO Definitive Biomarker [238]
CXCL1 TTLK1RW Definitive Altered Expression [867]
CXCR6 TT2BVUA Definitive Altered Expression [452]
DDR1 TTI1FPZ Definitive Altered Expression [226]
DEK TT1NMGV Definitive Biomarker [868]
DKK3 TTY2ZV6 Definitive Biomarker [869]
DNMT3B TT6VZ78 Definitive Biomarker [870]
E2F3 TTWIJYH Definitive Biomarker [871]
EDNRA TTKRD0G Definitive Altered Expression [452]
EGLN1 TT9ISBX Definitive Genetic Variation [872]
EML4 TT92GY4 Definitive Biomarker [873]
ENG TTB30LE Definitive Biomarker [874]
EPHA2 TTRJB2G Definitive Altered Expression [875]
EPHB4 TTI4ZX2 Definitive Altered Expression [876]
ERBB3 TTSINU2 Definitive Genetic Variation [877]
ESR1 TTZAYWL Definitive Genetic Variation [210]
FDPS TTIKWV4 Definitive Biomarker [878]
FKBP4 TTHY0FT Definitive Biomarker [879]
FKBP5 TT0J5KQ Definitive Biomarker [879]
FLT4 TTDCBX5 Definitive Biomarker [880]
FZD10 TTP1S2F Definitive Biomarker [881]
HHAT TT1VNCG Definitive Biomarker [882]
HLA-A TTHONFT Definitive Altered Expression [883]
IGF2R TTPNE41 Definitive Genetic Variation [884]
IGFBP2 TTU4QSN Definitive Altered Expression [885]
IL1A TTPM6HI Definitive Biomarker [886]
IL4 TTLGTKB Definitive Biomarker [887]
ITGA5 TTHIZP9 Definitive Altered Expression [888]
ITGAV TTT1R2L Definitive Altered Expression [889]
ITPR1 TT5HWAT Definitive Altered Expression [890]
ITPR3 TTH1769 Definitive Altered Expression [890]
KISS1 TTU2O6T Definitive Altered Expression [891]
KITLG TTDJ51N Definitive Genetic Variation [892]
KLF4 TTTI53X Definitive Biomarker [893]
LAMP1 TTC214J Definitive Biomarker [284]
LDHA TTW76JE Definitive Biomarker [894]
LRRC32 TT0FAYT Definitive Biomarker [895]
MAPK7 TTU6FSC Definitive Biomarker [896]
MAPK9 TT3IVG2 Definitive Biomarker [897]
MLH1 TTISG27 Definitive Altered Expression [898]
MSH2 TTCAWRT Definitive Biomarker [898]
NAMPT TTD1WIG Definitive Altered Expression [899]
NEK9 TTM57AW Definitive Biomarker [900]
NQO1 TT8XK6L Definitive Biomarker [901]
NR4A1 TTMXE2Q Definitive Biomarker [902]
NRP2 TTRXUVC Definitive Altered Expression [903]
PAH TTGSVH2 Definitive Biomarker [904]
PBK TTMY6BZ Definitive Biomarker [340]
PCNA TTLG1PD Definitive Altered Expression [905]
PDCD1LG2 TTW14O3 Definitive Biomarker [906]
PFKFB2 TTQYVKD Definitive Posttranslational Modification [376]
PHB TT6U071 Definitive Altered Expression [907]
PKD2L1 TTAHD89 Definitive Biomarker [880]
PKM TT4LOT8 Definitive Biomarker [908]
PLK1 TTH4IP0 Definitive Biomarker [909]
PLK4 TTGPNZQ Definitive Biomarker [910]
PNP TTMCF1Y Definitive Biomarker [911]
PPM1D TTENJAB Definitive Biomarker [912]
PROM1 TTXMZ81 Definitive Biomarker [913]
PRTN3 TT5MLC4 Definitive Genetic Variation [914]
PTPRJ TTWMKXP Definitive Genetic Variation [915]
RAPGEF3 TTOE7I0 Definitive Biomarker [396]
RASA1 TTPNZ1F Definitive Biomarker [916]
RGS6 TTJ96M8 Definitive Biomarker [916]
RORA TT1TYN7 Definitive Altered Expression [917]
RXRA TT6PEUO Definitive Biomarker [918]
SCARB1 TTRE324 Definitive Biomarker [919]
SDC1 TTYDSVG Definitive Altered Expression [410]
SIRT2 TTLKF5M Definitive Biomarker [920]
SLAMF6 TTSIYJ6 Definitive Biomarker [921]
SLC38A7 TTEARWC Definitive Altered Expression [922]
SPARC TTBQFM7 Definitive Altered Expression [923]
SPHK1 TTOHFIY Definitive Biomarker [924]
STAT1 TTN7R6K Definitive Biomarker [925]
STMN1 TT7W5OT Definitive Altered Expression [926]
STS TTHM0R1 Definitive Biomarker [439]
TBK1 TTMP03S Definitive Altered Expression [724]
TFAP2A TTDY4BS Definitive Biomarker [927]
TKTL1 TTNQ1J3 Definitive Biomarker [928]
TNFRSF18 TTG6LA7 Definitive Biomarker [762]
TNFRSF4 TTL31H0 Definitive Biomarker [929]
TNFSF11 TT9E8HR Definitive Biomarker [930]
TSPO TTPTXIN Definitive Biomarker [230]
USP14 TTVSYP9 Definitive Biomarker [931]
------------------------------------------------------------------------------------
⏷ Show the Full List of 864 DTT(s)
This Disease Is Related to 13 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ATP7A DT0LT17 Limited Biomarker [932]
SLC24A5 DTAWCS9 Limited Altered Expression [933]
SLC39A12 DT1UIT5 Limited Biomarker [285]
ABCB8 DT0KQND moderate Altered Expression [934]
SLC25A25 DTN7X5J moderate Biomarker [935]
SLC25A3 DTCRIWV moderate Altered Expression [936]
ABCA12 DT7LDG0 Strong Genetic Variation [937]
ABCB5 DTKVEXO Strong Biomarker [639]
SLC25A16 DTNU9EW Strong Biomarker [210]
SLC26A1 DTJ785O Strong Altered Expression [819]
SLC27A1 DTKDTML Strong Biomarker [938]
SLC52A1 DT7NOKR Strong Altered Expression [821]
SLC2A3 DT9SQ3L Definitive Altered Expression [939]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 DTP(s)
This Disease Is Related to 28 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ASNS DEXISVQ Limited Altered Expression [195]
CPA4 DEXKD7J Limited Biomarker [940]
CRMP1 DE0EUXB Limited Biomarker [443]
CYP27B1 DE3FYEM Limited Altered Expression [941]
GGCT DEKW6PB Limited Genetic Variation [942]
GLS DE3E0VT Limited Altered Expression [943]
HINT1 DEWJATF Limited Biomarker [944]
HK1 DEDMAGE Limited Genetic Variation [376]
MAT2B DEKF1OH Limited Altered Expression [945]
MT1A DE5ME8A Limited Posttranslational Modification [946]
NAT10 DEZV4AP Limited Biomarker [947]
NNMT DECVGJ3 Limited Altered Expression [948]
NT5C2 DE1DOKJ Limited Biomarker [949]
PSAT1 DEBS17P Limited Altered Expression [324]
HPRT1 DEVXTP5 moderate Biomarker [950]
ACP5 DESITDW Strong Biomarker [951]
AKR1B10 DEP6GT1 Strong Biomarker [823]
ALDH1A1 DE2JP1Y Strong Altered Expression [952]
CMPK1 DEMPH4I Strong Genetic Variation [953]
CYP2R1 DEBIHM3 Strong Biomarker [954]
HSD17B12 DE915QP Strong Genetic Variation [955]
NDUFS7 DEIW03B Strong Genetic Variation [956]
P3H2 DELB5PA Strong Posttranslational Modification [957]
P4HA3 DE2L4RX Strong Altered Expression [958]
PARK7 DEPOVCH Strong Altered Expression [959]
SCLY DEH4TD6 Strong Altered Expression [960]
UGT2B10 DEI8NGH Strong Biomarker [823]
PTGDS DER3H9C Definitive Altered Expression [961]
------------------------------------------------------------------------------------
⏷ Show the Full List of 28 DME(s)
This Disease Is Related to 1339 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AADAC OT8VACT2 Limited Biomarker [962]
ACAD10 OTFAG3M0 Limited Altered Expression [963]
ACSL3 OT3MWER1 Limited Biomarker [964]
ACSS1 OT6C1WQD Limited Biomarker [965]
ADAM15 OTZ7VLTP Limited Biomarker [966]
ADAR OTQNOHR8 Limited Altered Expression [967]
AFAP1L2 OTJBI0VN Limited Genetic Variation [488]
AGAP3 OT8C6PKL Limited Biomarker [968]
AHNAK OT6KH1WG Limited Biomarker [969]
AIM2 OT86QUI8 Limited Biomarker [970]
AKT1S1 OT4JHN4Y Limited Biomarker [971]
ALPP OTZU4G9W Limited Biomarker [189]
AMIGO2 OTPAIT1O Limited Biomarker [972]
APCDD1 OTV9AD0L Limited Biomarker [973]
ARHGAP45 OTL86FEQ Limited Biomarker [974]
ARHGEF5 OTUVGFT9 Limited Biomarker [975]
ARID2 OTIRJXWM Limited Biomarker [976]
ARL5B OTYYBIDG Limited Biomarker [285]
ART3 OT68OFVT Limited Biomarker [977]
ASAH1 OT1DNGXL Limited Altered Expression [978]
ASXL1 OTX931AW Limited Biomarker [979]
ATG10 OTVRPC5X Limited Biomarker [980]
ATG16L1 OTEOYC5D Limited Altered Expression [980]
ATN1 OTNZFLKY Limited Biomarker [981]
ATP13A2 OTKWBUGK Limited Genetic Variation [982]
ATP2B4 OTMWFDAC Limited Altered Expression [983]
B4GALNT1 OTCY80HS Limited Altered Expression [984]
BAD OT63ERYM Limited Altered Expression [877]
BASP1 OTF4VS5G Limited Altered Expression [783]
BATF3 OTI61WXQ Limited Genetic Variation [985]
BCAR1 OTKT2C2N Limited Biomarker [986]
BHLHE40 OTITX14U Limited Biomarker [987]
BIK OTTH1T3D Limited Biomarker [988]
BNIP3 OT4SO7J4 Limited Biomarker [989]
BPTF OTD1RZAD Limited Altered Expression [990]
BRMS1L OTJIW47U Limited Biomarker [991]
BTRC OT2EZDGR Limited Genetic Variation [992]
CACUL1 OT6P1ZVP Limited Altered Expression [993]
CANX OTYP1F6J Limited Biomarker [426]
CAP2 OTC1WFNO Limited Altered Expression [994]
CBLIF OTNE20WU Limited Biomarker [995]
CBLL2 OTB4AD3V Limited Biomarker [993]
CCDC8 OTO295IH Limited Biomarker [426]
CCL14 OT8QETQU Limited Biomarker [996]
CCL27 OTUZYC61 Limited Altered Expression [997]
CCL4L2 OTDBSXOU Limited Altered Expression [222]
CCN4 OT69BER9 Limited Altered Expression [998]
CCNF OTJFVU43 Limited Altered Expression [999]
CD207 OTI9RUDN Limited Genetic Variation [1000]
CD8A OTDWQJXK Limited Biomarker [1001]
CDC5L OTTPFUU5 Limited Altered Expression [1002]
CDC6 OTX93FE7 Limited Biomarker [1003]
CDCA4 OT0AAXAC Limited Biomarker [1004]
CDK16 OTUBXIIT Limited Altered Expression [900]
CDK2AP2 OTR99SJ8 Limited Biomarker [1005]
CDT1 OTVY53VG Limited Biomarker [1003]
CDX2 OTCG4TSY Limited Genetic Variation [1006]
CELF1 OT6JQ5RS Limited Biomarker [1007]
CEP350 OT5Q3AEA Limited Biomarker [1008]
CERS6 OTOP4GV1 Limited Biomarker [1009]
CFDP1 OTXY7J96 Limited Biomarker [444]
CHL1 OT6E6E8P Limited Biomarker [912]
CIB1 OT4BVCRU Limited Biomarker [1010]
CIITA OTRJNZFO Limited Altered Expression [1011]
CITED1 OTUJQ3VL Limited Biomarker [1012]
CKS1B OTNUPLUJ Limited Altered Expression [1013]
CLDN11 OTNN6UTL Limited Biomarker [753]
CLEC14A OT0UJQ4O Limited Altered Expression [1014]
CNGB1 OTA5DE38 Limited Biomarker [895]
COL17A1 OTID5AH2 Limited Biomarker [1015]
COMP OTS2FPMI Limited Biomarker [1016]
CPA3 OTOK8M0V Limited Altered Expression [940]
CPEB4 OTW1SCZW Limited Biomarker [1017]
CPT1A OTI862QH Limited Genetic Variation [1018]
CSAD OT3I2G0A Limited Biomarker [1019]
CSDE1 OT15D7GH Limited Biomarker [361]
CTAG2 OT8HISP4 Limited Biomarker [1020]
CTBP1 OTVYH2DH Limited Altered Expression [1021]
CTCF OT8ZB70U Limited Biomarker [1022]
CTHRC1 OTV88X2G Limited Biomarker [1023]
CTNND1 OTUMPSHR Limited Posttranslational Modification [1024]
CUL1 OTXPE1UZ Limited Biomarker [993]
CXCL16 OTD49T9R Limited Biomarker [1025]
DAPK2 OTWODUQG Limited Biomarker [443]
DCBLD1 OTA702JK Limited Biomarker [285]
DCLRE1C OTW3KB1I Limited Biomarker [1026]
DCP1A OT3NCON3 Limited Altered Expression [1027]
DCTN2 OTMB4IXD Limited Biomarker [1028]
DCTN4 OTM7C943 Limited Biomarker [323]
DCTN5 OTESGJ1N Limited Biomarker [1028]
DDB1 OTTR2L3Z Limited Altered Expression [1029]
DDIT3 OTI8YKKE Limited Biomarker [1030]
DDX3X OTDO4TRX Limited Altered Expression [1031]
DDX53 OTHK3EGZ Limited Biomarker [1032]
DENR OTXP9HOY Limited Biomarker [443]
DGKI OTDZ602D Limited Genetic Variation [1033]
DLG2 OTQ3BD8U Limited Biomarker [285]
DNAJB4 OTUD01BK Limited Altered Expression [1034]
DSG2 OTJPB2TO Limited Altered Expression [1035]
DST OTHZBM4X Limited Biomarker [1036]
DUSP6 OT4H6RKW Limited Biomarker [1037]
EBF1 OTZ61YYH Limited Genetic Variation [1038]
EBF3 OTB0IWLW Limited Altered Expression [1039]
EDA OTAKS5WS Limited Biomarker [285]
EDEM1 OTWHN69S Limited Biomarker [1040]
EDIL3 OTDVVNS0 Limited Altered Expression [1041]
EDN3 OTN7Q9BE Limited Altered Expression [1042]
EIF1AX OTWG2LAB Limited Genetic Variation [1043]
EIF2B1 OT4NCVY1 Limited Biomarker [1044]
EIF2B2 OTQQMHM1 Limited Biomarker [1044]
EIF2B4 OTTM5SX1 Limited Biomarker [1044]
EIF2S2 OTXF0B09 Limited Biomarker [1044]
EIF3D OTDOMP80 Limited Biomarker [1045]
EIF3I OTE07WND Limited Biomarker [1046]
EIF4A2 OT08H03R Limited Altered Expression [1047]
EIF4G1 OT2CF1E6 Limited Altered Expression [1047]
EIF4G2 OTEO98CR Limited Biomarker [444]
ELK4 OTVSSEOE Limited Altered Expression [1048]
ERCC4 OTFIOPG1 Limited Genetic Variation [1049]
ERCC5 OTQAKFJM Limited Genetic Variation [1050]
ERRFI1 OT7VZ2IZ Limited Altered Expression [1014]
ESRP1 OTNCS4SL Limited Altered Expression [1051]
ETFA OTXX61VZ Limited Biomarker [1052]
ETV1 OT6PMJIK Limited Altered Expression [1053]
EXO1 OTI87RS5 Limited Altered Expression [1054]
EYA1 OTHU807A Limited Altered Expression [1055]
FAH OTGZA1YR Limited Biomarker [1002]
FAM3C OTBR6U9G Limited Biomarker [1056]
FANCD2 OTVEB5LF Limited Biomarker [469]
FBXW4 OTEGSZOX Limited Biomarker [962]
FERMT2 OTZNPWWX Limited Biomarker [323]
FERMT3 OTFQOT3C Limited Altered Expression [1057]
FGF5 OTQXGHBY Limited Biomarker [1058]
FHOD1 OTROM7N3 Limited Altered Expression [1059]
FIS1 OT2HL10J Limited Biomarker [1060]
FLG OTE9QDV6 Limited Biomarker [1036]
FLII OT7G9JG6 Limited Biomarker [1061]
FLNB OTPCOYL6 Limited Biomarker [711]
FMR1 OTWEV0T5 Limited Altered Expression [1062]
FNDC3B OTBILGDR Limited Biomarker [1063]
FOSB OTW6C05J Limited Altered Expression [1064]
FOXA2 OTJOCVOY Limited Biomarker [1065]
FOXD3 OTXYV6GO Limited Biomarker [1066]
FUNDC2 OTY3TQM5 Limited Biomarker [996]
FUT1 OTODG57A Limited Altered Expression [1067]
FUT2 OTLXM6WI Limited Altered Expression [1067]
FUT8 OTJJCVG1 Limited Biomarker [1068]
FXR1 OTEMQ1SR Limited Altered Expression [1069]
GBE1 OTK2N05B Limited Biomarker [1070]
GBP1 OTUM7RPJ Limited Biomarker [1071]
GC OTWS63BY Limited Genetic Variation [1072]
GEMIN4 OTX7402E Limited Biomarker [444]
GINS2 OT974IYI Limited Altered Expression [1073]
GLIS3 OTBC960E Limited Biomarker [1074]
GMPR OTERWHYM Limited Biomarker [1075]
GNA12 OT3IRZH3 Limited Biomarker [281]
GNA14 OTYZ1ZI0 Limited Biomarker [232]
GOLM1 OTOZSV6O Limited Biomarker [1076]
GPC6 OTNJBESF Limited Biomarker [1077]
GPHA2 OT3HY17B Limited Biomarker [285]
GSTM2 OTG4WT05 Limited Genetic Variation [1078]
GYPA OTABU4YV Limited Biomarker [1079]
H2AZ1 OT3KJJNQ Limited Biomarker [1080]
HCLS1 OTX7WGYN Limited Biomarker [307]
HLA-DOA OTZE5Q7R Limited Biomarker [1081]
HLA-DQB1 OTVVI3UI Limited Biomarker [1082]
HM13 OTGEO1LP Limited Altered Expression [791]
HS2ST1 OTHOU8I2 Limited Biomarker [1083]
HSPA1A OTKGIE76 Limited Biomarker [1084]
HSPB2 OTS01646 Limited Biomarker [296]
HSPH1 OTVRR73T Limited Biomarker [1085]
ID4 OTPMJ39I Limited Biomarker [1086]
IFI30 OT9DERT1 Limited Altered Expression [1087]
IFNA17 OTHXRYG3 Limited Genetic Variation [1088]
IGSF8 OTU22IKI Limited Biomarker [1089]
IKBKG OTNWJWSD Limited Genetic Variation [1090]
IL17RB OT0KDNSF Limited Biomarker [249]
IL27 OTIS3OF8 Limited Altered Expression [527]
IL34 OTZ15VVK Limited Genetic Variation [1091]
IL4I1 OTK54C63 Limited Biomarker [887]
ILF3 OTKMZ5K5 Limited Altered Expression [1092]
IMMP1L OTA6LOLR Limited Altered Expression [791]
INCENP OT9HFRYK Limited Biomarker [285]
ING1 OTEZBRKW Limited Altered Expression [1093]
INO80 OTJBMS8T Limited Altered Expression [1094]
INPP4B OTLROA7G Limited Biomarker [1095]
IQGAP1 OTZRWTGA Limited Biomarker [1096]
IRF2 OTAZRUW3 Limited Biomarker [1097]
IRF6 OTKJ44EV Limited Altered Expression [1098]
IRF7 OTC1A2PQ Limited Altered Expression [1099]
IRF9 OTK4MYQJ Limited Altered Expression [1099]
IRS4 OTTOL40K Limited Biomarker [1100]
ITGA10 OTM0V5AO Limited Genetic Variation [315]
ITGA9 OTHN1IKA Limited Altered Expression [1101]
JUNB OTG2JXV5 Limited Altered Expression [1064]
JUND OTNKACJD Limited Altered Expression [1064]
KARS1 OT0EU4SV Limited Biomarker [944]
KDM6A OTZM3MJJ Limited Genetic Variation [320]
KHSRP OTDHZARB Limited Biomarker [1102]
LAMTOR2 OTHEDISB Limited Biomarker [1005]
LARP6 OTUQ9QS9 Limited Biomarker [1103]
LIMD2 OTSIFTD8 Limited Biomarker [1104]
LMO1 OTB59SKB Limited Genetic Variation [1105]
LOXL3 OTLLY1QI Limited Biomarker [1106]
LRBA OTOUZN9G Limited Biomarker [1107]
LRIG1 OTY5HZN5 Limited Biomarker [1108]
LRPPRC OTXSK5LP Limited Biomarker [368]
LSAMP OTYXVQX2 Limited Biomarker [1109]
LVRN OTHBF42S Limited Biomarker [193]
LXN OTZQ2M6Y Limited Altered Expression [269]
LYPLA1 OTENU47T Limited Biomarker [1110]
MACC1 OTV3DLX0 Limited Altered Expression [1111]
MAGI1 OTMV4ASV Limited Genetic Variation [1112]
MAGT1 OTQSAV5C Limited Biomarker [189]
MAP1LC3B OTUYHB84 Limited Altered Expression [748]
MAP2 OT6UYT3X Limited Altered Expression [1113]
MAP3K12 OT5HODDD Limited Biomarker [1114]
MAP3K13 OTS93BTX Limited Biomarker [1114]
MAPK6 OTDDNF3Q Limited Altered Expression [1115]
MAPK8IP2 OTDUHLN0 Limited Biomarker [1116]
MAVS OTTQ0J64 Limited Altered Expression [313]
MB OTYWYL2D Limited Biomarker [1117]
MCAT OTH07FIW Limited Biomarker [231]
MCTS1 OT7SAOJP Limited Biomarker [231]
MED19 OTT9RT5N Limited Altered Expression [1118]
MED27 OT40PZ9R Limited Biomarker [1119]
MEN1 OTN6U6V0 Limited Biomarker [1120]
MIA3 OTBVIZQD Limited Altered Expression [1121]
MIB2 OTJCC3HS Limited Biomarker [1122]
MINDY4 OTBZ2SZB Limited Biomarker [192]
MMRN1 OT7ZNYHT Limited Genetic Variation [1123]
MPC2 OT0GHXGG Limited Biomarker [1124]
MPEG1 OT7DAO0F Limited Biomarker [301]
MPPE1 OTINBJVE Limited Biomarker [1125]
MRPL41 OTG5URO4 Limited Biomarker [402]
MRTFA OTCVXASM Limited Altered Expression [1126]
MSN OTZJ4J6G Limited Biomarker [1127]
MSX1 OT5U41ZP Limited Biomarker [1128]
MUC13 OTWKS9MF Limited Biomarker [1129]
MUL1 OT2JC9YR Limited Biomarker [993]
MXD1 OTS5CTHX Limited Biomarker [387]
MYH10 OTXN2WXS Limited Biomarker [1130]
MYO10 OTHB78ZQ Limited Biomarker [1130]
MYO5A OTMWLP3E Limited Biomarker [1131]
MYOF OTRFC3IJ Limited Altered Expression [1132]
MYSM1 OTO73N00 Limited Biomarker [1133]
NAV2 OTGAOL01 Limited Posttranslational Modification [1134]
NEO1 OTGJ1997 Limited Altered Expression [1135]
NFAT5 OTKIE59S Limited Biomarker [1136]
NGLY1 OTZBQD5Q Limited Biomarker [1137]
NHS OTKE8QAT Limited Genetic Variation [1138]
NLRC4 OTAIA3NA Limited Genetic Variation [1139]
NME2 OTCYGLHV Limited Altered Expression [1140]
NOLC1 OTKDZU0D Limited Genetic Variation [1141]
NOX5 OTHTH59G Limited Altered Expression [1142]
NPAS2 OTMRT2TS Limited Genetic Variation [942]
NPNT OTFZAO1G Limited Altered Expression [1143]
NR2C2 OTDZWVOJ Limited Biomarker [341]
NRCAM OT80HHQ2 Limited Biomarker [1144]
NRF1 OTOXWNV8 Limited Altered Expression [1145]
NT5DC1 OTNI9MFH Limited Biomarker [285]
NTN4 OTDRRMP3 Limited Biomarker [1074]
NUCB2 OTHO6JWN Limited Biomarker [893]
NUDT1 OTZSES3W Limited Altered Expression [817]
NUMB OTMB586Q Limited Biomarker [889]
NUP62 OTMN63DH Limited Biomarker [323]
NUTM1 OTONYC08 Limited Biomarker [1146]
NXF1 OTEFHXG6 Limited Biomarker [711]
OCM OTQRML29 Limited Biomarker [1147]
OLIG2 OTMCN6D3 Limited Altered Expression [1148]
OPN1LW OTFNUZ7O Limited Biomarker [1149]
OPRPN OT6K1ZD6 Limited Genetic Variation [1150]
PAG1 OTFOJUIQ Limited Biomarker [1149]
PANX1 OTXPEDOK Limited Altered Expression [1151]
PARD3 OTH5BPLO Limited Biomarker [261]
PCBP4 OTDLL4NB Limited Biomarker [1149]
PCGF2 OTIY1J5L Limited Biomarker [858]
PCK2 OTJ8LX4N Limited Altered Expression [1152]
PDCD4 OTZ6NXUX Limited Biomarker [785]
PDHB OT2NHE5E Limited Biomarker [1153]
PDPN OTBUV19I Limited Biomarker [1154]
PEG10 OTWD2278 Limited Altered Expression [1155]
PHIP OTZY806Z Limited Biomarker [1156]
PHLPP1 OTIFXW8D Limited Altered Expression [1157]
PINK1 OT50NR57 Limited Biomarker [1158]
PITX1 OTA0UN4C Limited Altered Expression [1159]
PLAG1 OTT9AJQY Limited Altered Expression [324]
PLEC OTU4XDEG Limited Biomarker [1160]
PLIN2 OTRXJ9UN Limited Biomarker [1161]
PLP1 OT8CM9CX Limited Biomarker [375]
PLXNB1 OTCA7JIT Limited Biomarker [414]
PMAIP1 OTXEE550 Limited Genetic Variation [1162]
PNPT1 OTBR2Q0F Limited Biomarker [1163]
POLD1 OTWO4UCJ Limited Altered Expression [227]
PPA1 OTHZK1QB Limited Biomarker [1164]
PPARGC1A OTHCDQ22 Limited Biomarker [1165]
PPIP5K1 OT06HYH8 Limited Altered Expression [313]
PPP1R14A OTQODWZB Limited Biomarker [1166]
PPP1R14B OT9PTWAX Limited Biomarker [285]
PPP1R1A OTGTAGCV Limited Biomarker [1167]
PPP2R3B OT5Y53WZ Limited Biomarker [1003]
PRDM16 OT0BGA27 Limited Biomarker [1168]
PRDX6 OTS8KC8A Limited Genetic Variation [914]
PREX1 OTUTPVA9 Limited Biomarker [1169]
PRIMA1 OT9ITT3P Limited Genetic Variation [1162]
PROS1 OTXQWNOI Limited Altered Expression [324]
PSMD2 OT6HZHN7 Limited Biomarker [444]
PSME3 OTSTC4YY Limited Biomarker [1170]
PTX3 OTPXHRKU Limited Biomarker [1171]
PVR OT3N91T7 Limited Biomarker [1172]
PXDN OTFGGM9R Limited Biomarker [1074]
PXN OTVMMUOF Limited Altered Expression [986]
PYCR2 OTS2HLGD Limited Biomarker [1173]
RAB38 OTU0NZU0 Limited Biomarker [1174]
RAB3GAP1 OT4DQ8F2 Limited Genetic Variation [1141]
RAB5A OTFR2KM4 Limited Biomarker [1175]
RAB7B OT60A0E9 Limited Biomarker [395]
RABGEF1 OTWC3Z3R Limited Altered Expression [587]
RAD51AP1 OTXM7UTD Limited Biomarker [1176]
RANBP3 OTI8ESC3 Limited Altered Expression [1177]
RAP1A OT5RH6TI Limited Altered Expression [587]
RAP1GAP OTC31ONQ Limited Altered Expression [1178]
RARRES2 OT1BJE8K Limited Biomarker [1179]
RASGRP3 OTEMEV3P Limited Biomarker [1180]
RASSF10 OTGB7EBG Limited Biomarker [1181]
RASSF2 OT2JHDO4 Limited Altered Expression [1181]
RBL2 OTBQSOE6 Limited Genetic Variation [1141]
REG1A OTMHUH1D Limited Altered Expression [1182]
RFX6 OT8H77DL Limited Biomarker [285]
RGS5 OTUY0Q2I Limited Biomarker [1183]
RHCE OTS18IZ5 Limited Genetic Variation [1184]
RING1 OTCWTAX0 Limited Biomarker [1185]
RIPK3 OTL1D484 Limited Biomarker [1114]
RMC1 OT7K8MTJ Limited Biomarker [1186]
RNF123 OTL59S8J Limited Altered Expression [1187]
RNF44 OTGWL4U4 Limited Altered Expression [1188]
RPL17 OTTYMPS6 Limited Biomarker [485]
RPL22 OTVCN8K0 Limited Biomarker [254]
RPL36A OT1LYV85 Limited Altered Expression [1014]
RPL5 OTM8EBRI Limited Genetic Variation [1189]
RPP14 OT4OYFSK Limited Biomarker [1005]
RPS19 OTBKGP48 Limited Genetic Variation [1190]
RPS27 OTFXKY7P Limited Biomarker [301]
RPS6 OTT4D1LN Limited Genetic Variation [1191]
RRAS OTBBF28C Limited Altered Expression [1192]
SARDH OTQ49Q27 Limited Biomarker [1193]
SCIN OT6U09OL Limited Biomarker [1194]
SEC14L2 OTJST64D Limited Biomarker [1195]
SEC16A OTFNQ1ZU Limited Biomarker [1196]
SEC23A OTBRNIJ3 Limited Biomarker [1197]
SEM1 OTASLBM1 Limited Altered Expression [1198]
SEMA5A OTUOIOJV Limited Altered Expression [1199]
SERPINB4 OT88LHZ8 Limited Genetic Variation [415]
SF3B6 OTPRKS6S Limited Biomarker [1005]
SFN OTLJCZ1U Limited Biomarker [1200]
SFPQ OTLCIAPJ Limited Genetic Variation [1201]
SFRP2 OT8GZ0CA Limited Biomarker [1202]
SH3PXD2A OTYRQJIH Limited Altered Expression [1203]
SHARPIN OTU1J2KH Limited Biomarker [587]
SIAH2 OTKED2XN Limited Altered Expression [1204]
SIGLEC1 OTNWSQA9 Limited Biomarker [1205]
SIGLEC7 OTNDLURR Limited Biomarker [307]
SIX1 OT70YYWM Limited Altered Expression [1206]
SKIL OTNBXH32 Limited Altered Expression [1207]
SLC25A45 OTP7EAUM Limited Biomarker [285]
SLC2A4RG OTW3LX8D Limited Altered Expression [1208]
SLITRK1 OT1QQ7FR Limited Biomarker [1209]
SLN OTERIU75 Limited Biomarker [1210]
SLURP1 OT89YD2E Limited Biomarker [1211]
SMARCA2 OTSGJ8SV Limited Altered Expression [1212]
SMARCB1 OT2LP7LJ Limited Altered Expression [1213]
SMIM10L2B OT04IG2N Limited Biomarker [932]
SMR3B OTL5HNM8 Limited Biomarker [394]
SMS OT8JYKNH Limited Biomarker [1214]
SNAI3 OTG9DI66 Limited Altered Expression [1215]
SOCS2 OTBPNKJQ Limited Altered Expression [1216]
SPATA2 OTOA45GL Limited Biomarker [485]
SPEN OT37A2MD Limited Altered Expression [1217]
SPIN1 OT69VAOX Limited Biomarker [1218]
SPRED1 OTKX7P8G Limited Biomarker [1219]
SRA1 OTYOGMTG Limited Biomarker [1220]
SRL OT7IEBWZ Limited Biomarker [1193]
SS18L1 OT9ZEGV7 Limited Biomarker [1221]
SSR2 OTQJSL7M Limited Biomarker [1222]
STAG3 OTEV0AOD Limited Biomarker [1223]
STAP2 OTEB1VVI Limited Biomarker [1224]
STK11 OT1YZSP3 Limited Biomarker [1225]
STK19 OTYM6437 Limited Biomarker [1226]
STK3 OTLNSCQD Limited Biomarker [1227]
SULF1 OTJCNCO0 Limited Altered Expression [1228]
TAC4 OTYWPPM3 Limited Biomarker [504]
TAT OT2CJ91O Limited Biomarker [1229]
TBC1D16 OTPR3C6A Limited Biomarker [1230]
TBC1D9 OTSSCTB5 Limited Altered Expression [1231]
TBPL1 OT4I143E Limited Biomarker [1232]
TCHP OTVDMHSY Limited Biomarker [1233]
TEAD1 OTK6971C Limited Genetic Variation [1234]
TEAD4 OTJS0T2B Limited Genetic Variation [1234]
TFCP2 OTA246TE Limited Biomarker [1235]
TFE3 OTM99ZWH Limited Altered Expression [1236]
TFEB OTJUJJQY Limited Altered Expression [1236]
TFF3 OTJJDRTU Limited Biomarker [425]
TFG OT2KJENI Limited Genetic Variation [1237]
TGFBI OTR443C5 Limited Altered Expression [1238]
TIMELESS OTD8DCBJ Limited Biomarker [975]
TIMP2 OT8S1RRP Limited Biomarker [1239]
TMEM178B OTTQWHVU Limited Biomarker [1033]
TMEM31 OTKDPZD4 Limited Biomarker [1240]
TMEM45B OTVQCO8N Limited Altered Expression [1241]
TNFAIP8 OT1G9297 Limited Altered Expression [1242]
TNFSF9 OTV9L89D Limited Altered Expression [1243]
TP53I3 OTSCM68G Limited Biomarker [402]
TP53INP2 OT0GTBXO Limited Altered Expression [1244]
TPI1 OT14KP4B Limited Biomarker [975]
TRIB3 OTG5OS7X Limited Altered Expression [1245]
TRIM16 OTLRXYOZ Limited Biomarker [1246]
TRIP13 OTFM3TI9 Limited Biomarker [964]
TSC22D3 OT03UM03 Limited Biomarker [1247]
TSPYL4 OTHCX9RH Limited Biomarker [285]
AP2A1 OTEFZB21 Disputed Biomarker [1248]
APIP OT8ZABOU Disputed Biomarker [450]
ARHGEF2 OTBQTFRT Disputed Altered Expression [1208]
B3GAT1 OTXFP98E Disputed Altered Expression [504]
BCL2L11 OTNQQWFJ Disputed Biomarker [1249]
BLM OTEJOAJX Disputed Altered Expression [1250]
CCDC88C OTIU02BS Disputed Biomarker [1251]
CCL18 OT7JYSK9 Disputed Posttranslational Modification [1252]
CDC42 OT5QBC5M Disputed Genetic Variation [1253]
CDH13 OTD2CYM5 Disputed Biomarker [1254]
CEP85L OTSHJFOT Disputed Biomarker [450]
CLOCK OTNEOJY7 Disputed Genetic Variation [942]
CLTC OTBFASMA Disputed Biomarker [450]
CMAS OTFQJG3C Disputed Biomarker [1255]
CRISP2 OT8HLTV5 Disputed Biomarker [1256]
CRYBA1 OT8617WJ Disputed Genetic Variation [789]
DNLZ OT48CG1W Disputed Biomarker [1257]
FOXD1 OT80PRHS Disputed Altered Expression [1258]
GADD45A OTDRV63V Disputed Altered Expression [1259]
GCNT2 OTRUIMC4 Disputed Altered Expression [1260]
GPX4 OTRAFFX2 Disputed Biomarker [639]
HOXA1 OTMSOJ7D Disputed Altered Expression [1261]
IFI27 OTI2XGIT Disputed Biomarker [1262]
IGFBP4 OT2HZRBD Disputed Altered Expression [1263]
ING4 OT0VVG4V Disputed Biomarker [1264]
ISG20 OTCWRJJW Disputed Biomarker [1265]
KMT2B OTMMAZQX Disputed Biomarker [493]
LEF1 OTWS5I5H Disputed Biomarker [1266]
LOXL4 OT6XY2JL Disputed Biomarker [731]
LUM OTSRC874 Disputed Altered Expression [1267]
MOK OTQK7M9V Disputed Biomarker [584]
MPG OTAHW80B Disputed Biomarker [1268]
NOP14 OTKPM0Z5 Disputed Biomarker [1269]
OSR1 OTB19LEQ Disputed Biomarker [1270]
PEX3 OTGZ7ME2 Disputed Altered Expression [1271]
PFKFB4 OTQYEXL2 Disputed Altered Expression [417]
PIK3R3 OTXGJ8N1 Disputed Biomarker [1272]
PPP1R13L OTNCPLWE Disputed Altered Expression [1149]
PRKAA2 OTU1KZPV Disputed Biomarker [1273]
PRKAB1 OT1OG4QZ Disputed Biomarker [1273]
PRSS55 OTXXWI5Y Disputed Biomarker [1256]
PSMD9 OT6Y5CC3 Disputed Biomarker [1262]
PTPA OTRGFOI7 Disputed Altered Expression [1274]
PTPRD OTZPJ3GX Disputed Biomarker [1275]
PYCR1 OTQHB52T Disputed Altered Expression [1276]
RAB27A OT9SQRWY Disputed Biomarker [1277]
RBM3 OTAJ7R31 Disputed Altered Expression [1278]
RBX1 OTYA1UIO Disputed Altered Expression [993]
ROBO3 OTPVG40S Disputed Biomarker [461]
RPE OT0XT3JU Disputed Genetic Variation [789]
SART3 OTC1AM7S Disputed Altered Expression [1279]
SFRP5 OTLCVVSH Disputed Altered Expression [1280]
SGK3 OTQ6QO99 Disputed Biomarker [1281]
SLAMF9 OTH1OGZW Disputed Altered Expression [1282]
SLC12A9 OTR7VRAK Disputed Altered Expression [1283]
SMCP OTXKY794 Disputed Biomarker [639]
SOX4 OTSS40SS Disputed Altered Expression [1284]
SPRY4 OT2VK9N0 Disputed Biomarker [703]
SPZ1 OTQH8HJ5 Disputed Biomarker [1256]
STAMBP OTOT2OXM Disputed Altered Expression [1285]
SYNE2 OTBUXGQ0 Disputed Biomarker [892]
TAP2 OTWSYFI7 Disputed Biomarker [1286]
TBX2 OTTOT7A9 Disputed Biomarker [1287]
TFAM OTXXV5V7 Disputed Biomarker [1288]
TICAM2 OTK7GIJ5 Disputed Biomarker [1262]
TIMP3 OTDGQAD1 Disputed Altered Expression [1289]
TMED7 OTONO8E6 Disputed Biomarker [1262]
TNFRSF10C OTVHOL9B Disputed Altered Expression [1290]
TNFRSF10D OTOSRDJT Disputed Posttranslational Modification [1291]
A2M OTFTX90K moderate Biomarker [1292]
AANAT OTUBJ7SX moderate Biomarker [1293]
AATK OTVHAX5N moderate Altered Expression [1294]
ABI2 OT8GIIS5 moderate Genetic Variation [1295]
ACTRT1 OTHFKSIZ moderate Genetic Variation [1295]
ADAM12 OTZKOTDB moderate Genetic Variation [1296]
AEBP1 OTBI1RZ6 moderate Altered Expression [1297]
AGO2 OT4JY32Q moderate Altered Expression [1298]
AIMP1 OTTA5C3U moderate Altered Expression [1299]
AIRE OTA7G1Y1 moderate Genetic Variation [1300]
ALDH18A1 OT6W40XU moderate Biomarker [1301]
ANKK1 OT0OM1O0 moderate Genetic Variation [1302]
ANTXR1 OT5W1GPC moderate Biomarker [1303]
APOBEC3B OTHLNI51 moderate Biomarker [1304]
ARL6IP1 OT536XAV moderate Genetic Variation [1295]
ASXL2 OTNG4E2M moderate Biomarker [1305]
ASXL3 OTNDJWEZ moderate Biomarker [1305]
ATF6 OTAFHAVI moderate Biomarker [1306]
ATP2C1 OTQN51T3 moderate Genetic Variation [1307]
AXIN1 OTRGZGZ5 moderate Genetic Variation [1308]
BAG4 OTUPX3M2 moderate Altered Expression [1309]
BCAP31 OTKSACR4 moderate Biomarker [1310]
BCL3 OT1M5B95 moderate Biomarker [1311]
CACYBP OTJMZD2T moderate Biomarker [1312]
CAMLG OTTSRY39 moderate Altered Expression [1313]
CAPN3 OTCHG3YK moderate Altered Expression [1314]
CCDC6 OTXRQDYG moderate Genetic Variation [518]
CCL8 OTCTWYN8 moderate Altered Expression [1315]
CCN3 OTOW5YL4 moderate Biomarker [1316]
CCNC OTMVK4K4 moderate Biomarker [1317]
CD226 OT4UG0KB moderate Biomarker [1318]
CD81 OTQFXNAZ moderate Biomarker [1089]
CDH7 OTQEXCKU moderate Altered Expression [1319]
CDK11A OTN5TSGQ moderate Biomarker [1320]
CDKN3 OTBE3H07 moderate Genetic Variation [1321]
CIC OTFXCHNZ moderate Altered Expression [1322]
CKAP4 OTDUC9ME moderate Altered Expression [1323]
CLNS1A OT1HL9L1 moderate Biomarker [285]
CLPTM1 OT14QP7N moderate Genetic Variation [1324]
CLPTM1L OTDJWQXI moderate Genetic Variation [1325]
CNKSR3 OTXP4QH8 moderate Biomarker [1326]
CNN1 OTVPG39Z moderate Biomarker [451]
CNOT9 OT1NIIQD moderate Genetic Variation [1327]
CNTNAP5 OTF0AAJD moderate Biomarker [494]
CNTRL OTQI3VBA moderate Biomarker [1328]
COL4A1 OTL6D1YE moderate Biomarker [1329]
COL9A3 OTCUJOEK moderate Altered Expression [1330]
COX5A OTP0961M moderate Biomarker [1331]
CP OTM8JE4Y moderate Biomarker [1332]
CPOX OTIAY121 moderate Biomarker [1331]
CREM OTJIJ5AL moderate Altered Expression [1333]
CSMD2 OT541Z3W moderate Biomarker [494]
CTC1 OTRJY7QD moderate Biomarker [1334]
CTNNAL1 OTESJ6JD moderate Altered Expression [1335]
CTTN OTJRG4ES moderate Biomarker [1336]
DAB2IP OTF456VC moderate Genetic Variation [1295]
DAXX OTX6O7PL moderate Genetic Variation [1337]
DBF4 OTBL7JHQ moderate Biomarker [1338]
DDB2 OTO8HVVB moderate Biomarker [1029]
DDX43 OTK1RYSK moderate Biomarker [1339]
DGUOK OT78HUZB moderate Altered Expression [1340]
DIDO1 OT9PB547 moderate Altered Expression [1341]
DNALI1 OTTB3L8N moderate Altered Expression [527]
DOCK3 OTF3YS2W moderate Biomarker [1342]
DRG1 OTIFYMI3 moderate Biomarker [1343]
DUSP14 OTGODFCR moderate Genetic Variation [1344]
ECM1 OT1K65VW moderate Altered Expression [1345]
EHD1 OTDMEKLV moderate Genetic Variation [1346]
EIF4A1 OTMTBX6N moderate Biomarker [1347]
ERCC3 OTVAW3P1 moderate Altered Expression [226]
ESCO1 OTZ9P12A moderate Biomarker [1348]
FBLN1 OT5MHHOP moderate Posttranslational Modification [1349]
FBRSL1 OT4BPXGG moderate Genetic Variation [1350]
FGF3 OT9PK2SI moderate Biomarker [1351]
GAGE1 OT53E50E moderate Biomarker [1352]
GAGE4 OTPB5C0O moderate Biomarker [1352]
GAGE5 OTFI6OVS moderate Biomarker [1352]
GHRH OT94U6MO moderate Biomarker [524]
GIPC2 OT68YFO1 moderate Genetic Variation [1353]
GIT1 OTHO92S5 moderate Biomarker [1354]
GNA13 OTVDL515 moderate Altered Expression [1355]
GNMT OT0O2OQO moderate Biomarker [1356]
GOSR1 OTX8TMVU moderate Altered Expression [527]
GPAT2 OTZ8VP2Y moderate Altered Expression [1357]
H2AX OT18UX57 moderate Altered Expression [514]
HAS2 OTTD3PAL moderate Biomarker [1358]
HAS3 OTPM8IL8 moderate Altered Expression [1359]
HLA-E OTX1CTFB moderate Altered Expression [1360]
HMGCL OTRO9RII moderate Genetic Variation [1361]
HOXB7 OTC7WYU8 moderate Biomarker [1362]
HS3ST5 OTOB6Z3F moderate Biomarker [285]
IFIT2 OTI4EOAR moderate Altered Expression [534]
IGF2BP3 OTB97VIK moderate Altered Expression [719]
IL20RA OTSIVBVS moderate Altered Expression [1363]
IL20RB OTHFXK95 moderate Biomarker [1363]
IL9R OTILCLXA moderate Biomarker [1364]
ILKAP OT2A6FSA moderate Biomarker [1365]
ING2 OT6H0EWF moderate Altered Expression [1366]
INPP5E OTJF2AZ9 moderate Altered Expression [533]
INPP5K OTQFLQKA moderate Biomarker [1367]
INTS2 OT2N5TCK moderate Biomarker [1351]
KANK2 OT3SZIWM moderate Biomarker [1312]
KAT5 OTL7257A moderate Biomarker [1368]
KDM4B OT5P1UPY moderate Biomarker [536]
KIF23 OTY850JC moderate Biomarker [1369]
KIF5B OTT34MT8 moderate Biomarker [1370]
KIR3DL1 OTPOSXFX moderate Genetic Variation [468]
KLHL1 OTAX6SAD moderate Altered Expression [495]
LGALS7 OTMSVI7R moderate Altered Expression [1371]
LLGL1 OTAIQSXZ moderate Biomarker [1372]
LMLN OTQF0JPY moderate Biomarker [544]
LRAT OTB7CJKY moderate Altered Expression [1373]
MAGEB2 OTAGUVU5 moderate Biomarker [1300]
MAGED1 OT6EOLFC moderate Altered Expression [1374]
MAGED2 OTMEWNSE moderate Biomarker [1375]
MAGEH1 OTVE05K7 moderate Biomarker [307]
MAGI2 OTXDDKZS moderate Genetic Variation [1295]
MAML1 OTQA4DDN moderate Altered Expression [1376]
MAML2 OT1TSVAR moderate Biomarker [1377]
MARK1 OTP7KL47 moderate Biomarker [1378]
MCM2 OTGGORIQ moderate Biomarker [1379]
MGAT5 OTU4DD4G moderate Altered Expression [1380]
MICAL1 OTJEDVWA moderate Altered Expression [1381]
MICU1 OTS7N0LE moderate Biomarker [1382]
MLKL OTDSLC81 moderate Biomarker [1383]
MNT OTPC4ANL moderate Biomarker [1384]
MPST OTCDPH5D moderate Biomarker [501]
MSH3 OTD3YPVL moderate Altered Expression [181]
MST1 OTOC4UNG moderate Biomarker [544]
MTSS1 OT5DTDO2 moderate Biomarker [1385]
MX2 OT05NF37 moderate Genetic Variation [1386]
MYH6 OT3YNCH1 moderate Biomarker [1387]
MYO6 OTJQYRC7 moderate Biomarker [1387]
NCOA1 OTLIUJQD moderate Altered Expression [1388]
NCR3LG1 OT15YWU7 moderate Altered Expression [1389]
NDN OTYBYJ82 moderate Biomarker [1390]
NDUFS6 OT9IOONQ moderate Altered Expression [1391]
NEDD4L OT1B19RU moderate Biomarker [1392]
NEU1 OTH9BY8Y moderate Biomarker [1393]
NEURL1 OT2C4P70 moderate Biomarker [1393]
NFATC1 OT4TMERS moderate Biomarker [1394]
NFKBIE OTLAYEL9 moderate Biomarker [1395]
NPPA OTMQNTNX moderate Therapeutic [1396]
NRDE2 OTJ1V33O moderate Biomarker [494]
NSMAF OTYNVZ23 moderate Biomarker [1328]
NUS1 OT4DQ82L moderate Biomarker [285]
ODAM OTT666SJ moderate Biomarker [1397]
PAPPA OTTTG9PG moderate Biomarker [1398]
PBX1 OTORABGO moderate Biomarker [1399]
PBX2 OTEBYCAW moderate Biomarker [1400]
PDCD6IP OTS8T6A7 moderate Genetic Variation [1295]
PDIK1L OTISF4KG moderate Biomarker [1401]
PHF19 OTF6RUCR moderate Biomarker [1402]
PHLDA1 OTFTWMIQ moderate Biomarker [1403]
PIAS4 OTB7SVMZ moderate Altered Expression [1404]
PIK3C3 OTLUM9L7 moderate Biomarker [1405]
PLAA OTZ7NJGA moderate Genetic Variation [1406]
PLEK OTB73XXA moderate Posttranslational Modification [1407]
PLEKHM2 OT4ZYV73 moderate Biomarker [1367]
PLXND1 OTNK9ALK moderate Altered Expression [1408]
PNPLA2 OTR3ERMR moderate Biomarker [813]
POLE OTFM3MMU moderate Genetic Variation [1409]
POLN OTMHB3H8 moderate Genetic Variation [560]
POTEF OTV3WXYE moderate Biomarker [1410]
POU4F1 OTMHYGWQ moderate Altered Expression [1220]
PPP1R3B OTVCRXEZ moderate Biomarker [1411]
PTPRF OTH5KF2D moderate Altered Expression [936]
PTPRU OTHDO0QG moderate Altered Expression [936]
RAB40B OTCA9ZF5 moderate Posttranslational Modification [562]
RACGAP1 OTQE8IEH moderate Biomarker [1412]
RAD51B OTCJVRMY moderate Biomarker [1413]
RASEF OTGSAM2E moderate Altered Expression [1414]
RASSF6 OT25GVWY moderate Biomarker [1415]
RASSF8 OTXKGIB3 moderate Biomarker [1416]
RB1 OTQJUJMZ Moderate Autosomal dominant [1417]
RBM14 OTO9GMBD moderate Biomarker [1312]
RESF1 OTQIZIJF moderate Biomarker [1418]
REST OTLL92LQ moderate Biomarker [1419]
RIT1 OTVNOGOH moderate Altered Expression [1420]
RMDN1 OTE1NB6U moderate Biomarker [1421]
RMDN3 OTKO7AUM moderate Biomarker [1421]
RND3 OTXMXPIH moderate Biomarker [1422]
RNF125 OTBD1Q3X moderate Altered Expression [1423]
RNH1 OT6EC79B moderate Biomarker [1424]
ROPN1B OTPH2XLW moderate Altered Expression [1330]
RRM2B OTE8GBUR moderate Biomarker [1425]
RYBP OTZZ4P2Z moderate Biomarker [1426]
S100A13 OT582SUS moderate Altered Expression [1427]
S100A2 OTTGHJ1H moderate Biomarker [1428]
SAGE1 OT4H6FFA moderate Biomarker [1429]
SAT2 OT28QL7H moderate Altered Expression [1430]
SBF1 OTW6I9RV moderate Biomarker [1431]
SCG2 OTXWUQQL moderate Biomarker [1432]
SEPTIN4 OTD16B30 moderate Biomarker [1433]
SET OTGYYQJO moderate Altered Expression [1274]
SHOC2 OTUNQ2CT moderate Biomarker [1434]
SLC16A4 OT1YXBKC moderate Altered Expression [566]
SNRPD1 OTWKZV4E moderate Biomarker [1435]
SNW1 OTKWG3PS moderate Biomarker [1367]
SOS1 OTTCWXC3 moderate Genetic Variation [583]
SOX11 OT4LG7LA moderate Biomarker [1436]
SPANXA1 OTMK3QIS moderate Biomarker [1437]
SPANXB1 OTLMGC9T moderate Biomarker [1437]
SPANXC OT1033B9 moderate Biomarker [1437]
SPHKAP OT5RHUYJ moderate Biomarker [1367]
SPINT2 OTQV7BKQ moderate Biomarker [529]
SSX1 OTZ7NRCY moderate Biomarker [1438]
SSX4 OT0E4H2D moderate Biomarker [337]
ST6GALNAC2 OT9PBQVT moderate Biomarker [1439]
STIM1 OT8CLQ1W moderate Biomarker [552]
STIM2 OTYNXAW0 moderate Biomarker [1440]
STING1 OTDAP4G0 moderate Biomarker [1441]
SUZ12 OT655XF8 moderate Genetic Variation [1442]
SYBU OT3FQV7N moderate Biomarker [1421]
SYCE1L OTXU44F3 moderate Altered Expression [495]
SYN1 OTMNPWC1 moderate Altered Expression [1443]
SYNE1 OTSBSLUH moderate Genetic Variation [1444]
TAS2R38 OTX5MM36 moderate Genetic Variation [518]
TBP OT6C0S52 moderate Biomarker [1445]
TCEA1 OTBFO594 moderate Biomarker [1312]
TCL1B OT4CSO39 moderate Altered Expression [1443]
TES OTL8PP6V moderate Biomarker [1446]
TFAP2C OTUDIW05 moderate Biomarker [1345]
THY1 OTVONVTB moderate Altered Expression [1447]
TMED5 OT70W1J8 moderate Altered Expression [527]
TMPRSS13 OTMAOAP3 moderate Biomarker [544]
TP53INP1 OT2363Z9 moderate Biomarker [1312]
TRIB2 OTHSX3MX moderate Biomarker [1448]
TSACC OT3QW6PH moderate Biomarker [1312]
TTC4 OTAPMYXU moderate Genetic Variation [1449]
ACD OTC54EPO Strong Genetic Variation [1450]
ACER3 OTIVQBG5 Strong Biomarker [285]
ACTB OT1MCP2F Strong Altered Expression [683]
ADAMTS18 OTRMFI04 Strong Genetic Variation [1451]
ADAMTS20 OTU0EKLN Strong Biomarker [1452]
AFM OTPOR8IO Strong Biomarker [1453]
AGFG2 OTXQZHCR Strong Genetic Variation [1454]
AHSA1 OTC7AFHT Strong Biomarker [587]
AIFM1 OTKPWB7Q Strong Genetic Variation [1455]
ALDH1A3 OT1C9NKQ Strong Altered Expression [952]
ALDH3A1 OTAYZZE6 Strong Altered Expression [1456]
ALDH7A1 OTV57BZD Strong Altered Expression [1457]
ALLC OTZE4XV7 Strong Biomarker [1458]
ALX1 OTZVARA5 Strong Biomarker [1459]
AMBRA1 OTY0YGT9 Strong Altered Expression [1460]
AMFR OTQRX7LC Strong Altered Expression [1461]
AMPH OTWPGWZX Strong Biomarker [1462]
ANGPTL1 OTXIN6V5 Strong Biomarker [1463]
ANGPTL2 OTB6JG41 Strong Biomarker [1464]
ANXA6 OT9KIQ0Y Strong Altered Expression [1465]
ANXA9 OTKNYMU2 Strong Genetic Variation [1466]
APBB1IP OTN02KUV Strong Biomarker [1467]
APLF OTYUR3AH Strong Biomarker [1468]
ARHGAP22 OTXUQEFL Strong Posttranslational Modification [1134]
ARHGAP35 OTJ8POG0 Strong Biomarker [1469]
ARHGEF17 OTUGS4FL Strong Genetic Variation [1470]
ARHGEF7 OT9BPJCL Strong Altered Expression [1471]
ARL11 OTF6UDDB Strong Genetic Variation [1472]
ARMC9 OT0MZER2 Strong Biomarker [1473]
ARNT OTMSIEZY Strong Altered Expression [1474]
ARPC1B OTYE3DN2 Strong Biomarker [1475]
ARR3 OTRZ00CH Strong Biomarker [767]
ARTN OTWIWGL6 Strong Biomarker [585]
ASAP1 OT4DLRYY Strong Altered Expression [1476]
ASCC1 OTH4VAP9 Strong Altered Expression [1471]
ASF1A OT4S44GP Strong Genetic Variation [1477]
ASS1 OT4ZMG0Q Strong Altered Expression [1478]
ATG5 OT4T5SMS Strong Biomarker [1479]
ATP6V0D2 OTMOZJO0 Strong Altered Expression [1480]
AXIN2 OTRMGQNU Strong Genetic Variation [1481]
BANP OT1JMTBD Strong Altered Expression [1482]
BATF2 OT4XBZC9 Strong Biomarker [1483]
BCL10 OT47MCLI Strong Biomarker [1484]
BIRC6 OTCQJAB0 Strong Genetic Variation [1485]
BOP1 OTMZMQDO Strong Altered Expression [1486]
BRMS1 OTV5A6LL Strong Biomarker [991]
BUB1B OT8KME51 Strong Biomarker [1487]
BZW1 OT4GUFIG Strong Biomarker [285]
C11orf68 OTOKOGZ6 Strong Biomarker [285]
C16orf96 OTE0B1QV Strong Biomarker [1488]
CAMK2B OTS9YK3E Strong Altered Expression [1489]
CASC3 OTLK3K4U Strong Altered Expression [683]
CAST OTBXZZGF Strong Altered Expression [1490]
CCDC63 OTKDRXAE Strong Biomarker [823]
CCL16 OTOOQI1F Strong Biomarker [1491]
CCL25 OTLWJ8CJ Strong Altered Expression [1492]
CCNH OTKDU3SR Strong Altered Expression [226]
CD151 OTF3UZS7 Strong Biomarker [1493]
CD163L1 OTZHN1XQ Strong Biomarker [738]
CD1D OT3ROU4J Strong Biomarker [1494]
CD3D OTRBLP0R Strong Biomarker [1495]
CDCA2 OTX8UF9J Strong Altered Expression [1496]
CDCP1 OTD7RRWK Strong Biomarker [1497]
CDK5RAP1 OTDEJXD0 Strong Biomarker [1498]
CDKN2D OT2TTZPZ Strong Genetic Variation [1499]
CEACAM7 OTKFDTZY Strong Biomarker [228]
CENPS OTZ4J391 Strong Altered Expression [1500]
CERS2 OTRAHYYP Strong Genetic Variation [1466]
CETN1 OTGQ8JOZ Strong Biomarker [1501]
CH25H OT9S2BSW Strong Biomarker [1502]
CHD5 OTS5EVHH Strong Genetic Variation [1503]
CHI3L1 OT2Z7VJH Strong Altered Expression [1504]
CHST10 OTEDU5YC Strong Biomarker [1505]
CISD3 OT0MM1MW Strong Biomarker [1506]
CISH OT8T5NYL Strong Altered Expression [534]
CLEC1B OTO38TRG Strong Biomarker [1154]
CLTA OTLHOXMQ Strong Altered Expression [683]
CMPK2 OTOG90R0 Strong Genetic Variation [953]
CNNM1 OTHRSSGH Strong Biomarker [1507]
COL2A1 OT5E59C8 Strong Biomarker [1507]
COX2 OTTMVBJJ Strong Biomarker [1508]
COX6C OT3V7JE5 Strong Genetic Variation [1509]
CPQ OTTNZNLD Strong Biomarker [1510]
CPT1C OT8F1MBF Strong Biomarker [1507]
CRABP2 OTY01V9G Strong Altered Expression [1511]
CRACD OTII2U6L Strong Biomarker [1512]
CRYBG1 OTIPDI15 Strong Biomarker [1513]
CSGALNACT1 OTBML9D9 Strong Altered Expression [819]
CST6 OTZVHJTF Strong Biomarker [329]
CST8 OTT2FRCJ Strong Biomarker [1514]
CSTA OT1K68KE Strong Biomarker [1515]
CTAG1B OTIQGW6U Strong Altered Expression [640]
CTAGE1 OTWM7KSJ Strong Genetic Variation [1516]
CTNNBIP1 OTX9SBJG Strong Biomarker [1517]
CUX1 OTU1LCNJ Strong Altered Expression [1518]
CXADR OT9ZP02A Strong Biomarker [767]
CXCL6 OTFTCQ4O Strong Biomarker [1519]
CYTB OTAHB98A Strong Biomarker [1520]
DBT OT4KZ5R9 Strong Altered Expression [1521]
DCC OT2C1SHW Strong Biomarker [738]
DCTN6 OTI8PIN9 Strong Biomarker [1028]
DDAH2 OT8Q40G2 Strong Biomarker [1522]
DDIT4L OT26Z2KN Strong Biomarker [1507]
DDX41 OT6KEIHP Strong Altered Expression [1523]
DENND2D OTXEFJWM Strong Genetic Variation [1470]
DEPDC1B OTMVFOT1 Strong Altered Expression [1524]
DERA OT8SMO3N Strong Biomarker [1525]
DIAPH1 OTZBYPLH Strong Altered Expression [1526]
DKC1 OTX7DJR6 Strong Genetic Variation [1514]
DLEC1 OTMKKBUW Strong Biomarker [1527]
DNAH8 OTGES2OU Strong Altered Expression [1528]
DNAJB6 OTMHIIAN Strong Biomarker [1529]
DNAJC1 OTCKFOZ0 Strong Biomarker [285]
DNAJC15 OTNDUKAA Strong Biomarker [530]
DNAJC2 OT3JDA0R Strong Biomarker [1530]
DNASE1L3 OTEUIMC2 Strong Biomarker [1531]
DOCK10 OTI3MBLV Strong Altered Expression [1532]
DPH3 OT59Q6C4 Strong Biomarker [1533]
DRAP1 OTRWLF6D Strong Biomarker [285]
DRG2 OTFYAWE5 Strong Altered Expression [1534]
DSC1 OTNII6GZ Strong Biomarker [1535]
DSG1 OT11HC3A Strong Biomarker [1536]
DSP OTB2MOP8 Strong Altered Expression [936]
DSTN OTMXO4YB Strong Biomarker [1537]
DUSP4 OT6WAO12 Strong Biomarker [1538]
ECHDC1 OTMS00PY Strong Biomarker [285]
EDAR OT3W2UQS Strong Biomarker [1539]
EEF1A1 OT00THXS Strong Biomarker [1540]
EEF1E1 OTRA6XOB Strong Biomarker [597]
EFNA1 OTU2NUA2 Strong Biomarker [1541]
EGR3 OTGPJIRA Strong Biomarker [1542]
EIF1AD OT3EXB6S Strong Biomarker [285]
EIF3F OTU20K6L Strong Genetic Variation [1543]
ELOVL2 OTDAF6U3 Strong Genetic Variation [955]
ELP1 OTYEWBF7 Strong Biomarker [1544]
ELP5 OTW5R7YD Strong Biomarker [1544]
ELP6 OT0T3BLP Strong Biomarker [1544]
EPB41 OTGCFPV8 Strong Biomarker [530]
EPHX3 OTU7LW2F Strong Biomarker [1507]
ETV5 OTE2OBM4 Strong Altered Expression [1545]
FABP7 OTRE2H4G Strong Altered Expression [772]
FADD OTV7GFHH Strong Altered Expression [1546]
FAM20C OTW5YZ7X Strong Biomarker [1547]
FARP1 OTL1EBTM Strong Altered Expression [1548]
FAT4 OT7QONNV Strong Altered Expression [1549]
FBXO22 OTEJ5MO0 Strong Biomarker [1550]
FCRLA OT6MK4M1 Strong Biomarker [1551]
FLI1 OT0EV3LX Strong Altered Expression [1552]
FLOT2 OTZ0QR5L Strong Altered Expression [1553]
FOXN3 OTOJYJZP Strong Genetic Variation [1554]
FOXO3 OTHXQG4P Strong Altered Expression [1555]
FOXO4 OT90X9LN Strong Genetic Variation [1556]
FRS2 OTDMD800 Strong Biomarker [1557]
FRZB OTTO3DPY Strong Posttranslational Modification [1558]
FTL OTYQA8A6 Strong Biomarker [1559]
FXYD5 OT81DIOD Strong Altered Expression [1560]
FZD3 OTIWDN78 Strong Altered Expression [1561]
GAB1 OTQKE6V4 Strong Biomarker [1562]
GAB2 OTBFN705 Strong Genetic Variation [1563]
GAGE2A OTRAJ80C Strong Altered Expression [1564]
GALNT14 OT9BSDDQ Strong Altered Expression [1565]
GAPDHS OT7YUSA5 Strong Biomarker [1566]
GAS1 OTKJXG52 Strong Biomarker [1567]
GBP5 OTS4AO4A Strong Altered Expression [1568]
GFRA1 OT3WBVYB Strong Biomarker [1569]
GNS OTNFKYGB Strong Biomarker [1229]
GOLGA4 OTCMEHNJ Strong Genetic Variation [1570]
GOPC OTRBGH71 Strong Biomarker [285]
GPAM OTR1XD9B Strong Biomarker [285]
GPLD1 OTUUQOVY Strong Biomarker [1571]
GPR143 OTWUA2AV Strong Altered Expression [1572]
GPR151 OT7EACU6 Strong Biomarker [691]
GRAP2 OTS5NIZ3 Strong Biomarker [587]
GRK1 OT7MPSG7 Strong Altered Expression [806]
GRK7 OT083IH0 Strong Altered Expression [806]
GSDME OT1ZWY32 Strong Biomarker [1573]
GTF2H2 OTK72L9I Strong Altered Expression [226]
GTF2H3 OT87W5QJ Strong Altered Expression [226]
GTF2H4 OTPD1DIU Strong Altered Expression [226]
GTF2H5 OTRL219S Strong Altered Expression [226]
HAND2 OTCXYW4Y Strong Biomarker [401]
HCP5 OTV0YRI8 Strong Altered Expression [1574]
HERC2 OTNQYKOB Strong Genetic Variation [1575]
HIKESHI OTPKV3UZ Strong Biomarker [285]
HLA-DRB4 OTNXIHQU Strong Biomarker [1576]
HLA-F OT76CM19 Strong Biomarker [1577]
HNRNPD OT5UO1FA Strong Altered Expression [1578]
HNRNPK OTNPRM8U Strong Altered Expression [1579]
HOXA9 OTKNK5H0 Strong Biomarker [1507]
HOXC11 OT8NMHM6 Strong Altered Expression [1388]
HOXD12 OTKRUPGV Strong Biomarker [1507]
HOXD13 OTWSC8TF Strong Altered Expression [1580]
HOXD3 OTBUZ35T Strong Biomarker [1581]
HPR OTXSC9UB Strong Biomarker [1582]
HSF5 OT2IZ1CX Strong Biomarker [1583]
HSPA4 OT5HR0AR Strong Biomarker [1584]
HTRA2 OTC7616F Strong Biomarker [1445]
ICMT OT8CNKBO Strong Biomarker [1585]
IDH2 OTTQA4PB Strong Biomarker [1586]
IFITM3 OT2QP8D3 Strong Posttranslational Modification [1587]
IGF2BP1 OT9G360P Strong Biomarker [390]
IL1RAPL1 OTW3T4B2 Strong Biomarker [1588]
IL27RA OTSQBAKI Strong Altered Expression [1589]
IL2RG OTRZ3OMY Strong Biomarker [1590]
ING3 OTDIJXFP Strong Altered Expression [1591]
IQCH OTEYWCIW Strong Biomarker [285]
IRF5 OT8SIIAP Strong Genetic Variation [1592]
ITGA2B OT4Y17PY Strong Altered Expression [1593]
ITGAX OTOGIMHE Strong Altered Expression [1594]
JAKMIP2 OT2H3MRD Strong Biomarker [738]
JMJD6 OTILR7E4 Strong Biomarker [1595]
KCNH4 OTHJ8WTU Strong Biomarker [1596]
KCNIP3 OTCQPEM4 Strong Biomarker [1597]
KCTD12 OTPYKT4Z Strong Biomarker [1598]
KHDRBS2 OTEKL45T Strong Biomarker [823]
KIDINS220 OTLBH2MA Strong Altered Expression [1599]
KIF15 OTJRJEXL Strong Biomarker [1600]
KIF18B OTOBUDOE Strong Biomarker [1601]
KIF20A OTXOQHE0 Strong Biomarker [1602]
KIF7 OT1J6NAW Strong Altered Expression [1603]
KIR2DS4 OT00N6UJ Strong Altered Expression [1604]
KLF3 OTIIAC18 Strong Biomarker [1605]
KLF6 OTQY9S7F Strong Biomarker [1606]
KLF9 OTBFEJRQ Strong Biomarker [1607]
KLRB1 OTQ2959Y Strong Biomarker [1608]
KNL1 OT4Q3LHV Strong Altered Expression [1609]
KRT15 OTS6WLF7 Strong Biomarker [1610]
KRT16 OTGA0EQN Strong Biomarker [662]
KRT18 OTVLQFIP Strong Genetic Variation [1611]
LAMB2 OT71OI2Y Strong Biomarker [1612]
LAMTOR1 OTIBJBW9 Strong Biomarker [597]
LCP1 OTK61F2A Strong Altered Expression [1613]
LGR6 OTPZ1PWR Strong Biomarker [691]
LIG4 OT40DNXU Strong Genetic Variation [1614]
LRIT1 OTNEQPMZ Strong Biomarker [773]
LRP1B OT4YZG2N Strong Biomarker [1535]
LRP8 OTZ71YV2 Strong Biomarker [1615]
LSP1 OTSPSIFO Strong Altered Expression [1616]
LTBP2 OTS88GSD Strong Biomarker [1617]
LTBP3 OTME98V7 Strong Biomarker [1617]
LTBP4 OTC8WL2V Strong Biomarker [1618]
LYPD5 OTGP7UKA Strong Altered Expression [1619]
LYPLA2 OT03UIYC Strong Biomarker [1286]
LZTS1 OTXXL864 Strong Altered Expression [1620]
MAFK OTZJUE4P Strong Biomarker [597]
MAGEA12 OT8ULELL Strong Biomarker [1621]
MAGEB1 OTN7G8V1 Strong Altered Expression [1622]
MAGEE1 OTOQQO2X Strong Altered Expression [1623]
MAGEL2 OTXEL4R7 Strong Altered Expression [1390]
MATN1 OTBRTCTQ Strong Altered Expression [1624]
MAU2 OTALDF8Q Strong Biomarker [1625]
MCC OTQVI1EM Strong Genetic Variation [1626]
MCM3 OTOOHQPM Strong Altered Expression [1627]
MDH2 OT7364GY Strong Biomarker [1628]
MEIS1 OTH9DKAD Strong Biomarker [1629]
METTL3 OTSXP1M3 Strong Altered Expression [1630]
METTL4 OT061H4E Strong Biomarker [1631]
MFN1 OTCBXQZF Strong Biomarker [1060]
MFN2 OTPYN8A3 Strong Biomarker [1060]
MFSD12 OT54Y9TN Strong Biomarker [1632]
MGP OTZWU3FU Strong Biomarker [1514]
MGRN1 OTFZC41K Strong Altered Expression [1633]
MICA OTPEIEAR Strong Biomarker [1634]
MICB OTS2DVDW Strong Biomarker [1634]
MLLT10 OTURMDV7 Strong Biomarker [285]
MMP25 OT3BG37V Strong Biomarker [409]
MMP26 OT9O89KU Strong Altered Expression [1635]
MOGS OT99MBGB Strong Biomarker [1636]
MOS OTNMQPFJ Strong Biomarker [1637]
MRGPRX3 OTRKCCDS Strong Biomarker [691]
MRGPRX4 OTOBHZVA Strong Biomarker [691]
MRPL19 OTRBKF6R Strong Altered Expression [683]
MRPL40 OTB2QZDY Strong Altered Expression [1638]
MRPL49 OTN5PNSP Strong Biomarker [285]
MSX2 OT1WDKE1 Strong Biomarker [1639]
MT1E OTXJKU4Y Strong Posttranslational Modification [1640]
MTPAP OT6HQ02S Strong Biomarker [285]
MX1 OT6X8G5T Strong Biomarker [863]
MYDGF OT9HRPL6 Strong Biomarker [713]
MYH7B OTCB2IJB Strong Genetic Variation [783]
MYL9 OT6B22JB Strong Altered Expression [1641]
MYO7A OTBZSPEL Strong Biomarker [865]
MZF1 OTMVZCPW Strong Biomarker [1642]
NAT9 OT4ZKCRS Strong Biomarker [1643]
NAV3 OT97M1TR Strong Genetic Variation [1644]
NCAPG OT1AI9EO Strong Altered Expression [1645]
NCK2 OTUYPF55 Strong Altered Expression [1646]
NCOA6 OTOMIGTV Strong Genetic Variation [550]
NDRG1 OTVO66BO Strong Altered Expression [1647]
NEU3 OTQ5PQOW Strong Altered Expression [1648]
NF1 OTC29NHH Strong Biomarker [1167]
NLK OT2LETFS Strong Altered Expression [1649]
NMI OTYVG3NM Strong Biomarker [1650]
NMT1 OT42GQ3D Strong Altered Expression [1190]
NONO OTN36Q6U Strong Altered Expression [1651]
NPAP1 OTECLRPR Strong Biomarker [738]
NPC2 OTE9UEJC Strong Biomarker [1514]
OAS1 OT8ZLOCY Strong Altered Expression [534]
OCA2 OTDWIGBF Strong Biomarker [1652]
OS9 OTB5B2TY Strong Genetic Variation [1653]
OVOL1 OTFJ62UI Strong Biomarker [1654]
OVOL2 OTFM1GKF Strong Biomarker [1654]
PAEP OTQA0NV4 Strong Biomarker [1655]
PAQR3 OTTKJ9Y4 Strong Biomarker [1656]
PAX2 OTKP1N8F Strong Altered Expression [1657]
PAX6 OTOC9876 Strong Biomarker [1507]
PCDHB8 OTRF344J Strong Biomarker [823]
PCLAF OTMVIOUU Strong Biomarker [459]
PDCD6 OT2YA5M8 Strong Altered Expression [1658]
PDIA3 OTHPQ0Q3 Strong Altered Expression [1659]
PDSS2 OTEOQBMX Strong Altered Expression [1660]
PEG3 OTHQW98S Strong Biomarker [1661]
PERP OTP0YL53 Strong Altered Expression [1662]
PGK1 OT6V1ICH Strong Altered Expression [1467]
PGLYRP1 OTBTPR2T Strong Biomarker [1663]
PI3 OT47MTC3 Strong Altered Expression [1664]
PIAS2 OTJLSC3V Strong Biomarker [1665]
PIDD1 OTWFM930 Strong Biomarker [1501]
PIP4K2A OTO9JO9U Strong Biomarker [285]
PIR OT8ALXHU Strong Biomarker [1666]
PKD1 OT5ALRZ5 Strong Biomarker [662]
PKP1 OT9HSQ8F Strong Altered Expression [1667]
PKP3 OTPL1HRB Strong Biomarker [1668]
PLAAT4 OTI66SAJ Strong Biomarker [461]
PLCB2 OTPAHDGO Strong Biomarker [1669]
PLCB4 OTPA0QHW Strong Genetic Variation [1670]
PLEK2 OTUBWUUK Strong Biomarker [608]
PMP2 OTKYV2NE Strong Biomarker [1671]
PODXL OTPNQXF3 Strong Altered Expression [1041]
POLDIP2 OT8SZSJ6 Strong Biomarker [587]
POU2F1 OTK7ELJ0 Strong Biomarker [1672]
POU3F2 OT30NFOC Strong Biomarker [1673]
PPP1R15A OTYG179K Strong Biomarker [1674]
PPP2R1A OTYA3GB4 Strong Genetic Variation [1675]
PPP6C OTR1STMJ Strong Genetic Variation [1676]
PRDM2 OT8L7CGX Strong Genetic Variation [1677]
PRDX2 OTLWCY9T Strong Biomarker [1507]
PRKAA1 OT7TNF0L Strong Biomarker [1273]
PRKD3 OT987HJI Strong Biomarker [1678]
PRSS23 OT6DQAM1 Strong Biomarker [285]
PSD4 OTEFB87Z Strong Biomarker [1679]
PSG2 OT2EIXAI Strong Biomarker [228]
PSMC5 OTJOORMR Strong Altered Expression [1680]
PSMD11 OT8KO67V Strong Biomarker [979]
PSMD3 OT585WY8 Strong Biomarker [979]
PTBP2 OTF4S7NE Strong Altered Expression [1681]
PTER OTBYJHDG Strong Biomarker [285]
PTPRK OTAP5AT3 Strong Biomarker [285]
PTPRO OTFLKWOY Strong Biomarker [823]
PUDP OTEPEJLX Strong Genetic Variation [1682]
RAB8A OTPB54Y3 Strong Biomarker [1683]
RABGAP1L OT7QO47I Strong Biomarker [771]
RAC2 OTAOHFNH Strong Biomarker [1684]
RAG1 OTV131E4 Strong Biomarker [1685]
RAG2 OTG9UYTW Strong Biomarker [1590]
RAI1 OTKLQU00 Strong Biomarker [285]
RALGDS OTG36NI7 Strong Biomarker [1686]
RAP2B OTD2NDQP Strong Altered Expression [1687]
RAPGEF5 OT53VS75 Strong Biomarker [1688]
RASA2 OTL06RG2 Strong Altered Expression [1192]
RASD1 OT2BAJHK Strong Biomarker [1175]
RASGRF1 OTNWJ7EN Strong Biomarker [1689]
RASSF1 OTEZIPB7 Strong Biomarker [753]
RASSF7 OT0V4EIZ Strong Genetic Variation [1690]
RAX OTJ3YCE7 Strong Biomarker [1507]
RB1 OT9VMY7B Strong Posttranslational Modification [423]
RBM45 OTWTHD77 Strong Genetic Variation [1691]
RBP1 OTRP1MFC Strong Altered Expression [1692]
RBP2 OTR8QG5V Strong Altered Expression [1511]
RCAN1 OT1MVXC7 Strong Altered Expression [1693]
REC8 OT6JAVXE Strong Biomarker [1507]
RECQL4 OT59LSW7 Strong Biomarker [1694]
RGPD2 OTMUZ0HX Strong Genetic Variation [1454]
RHEB OTFLTSEC Strong Biomarker [1695]
RHOC OTOLE1FT Strong Altered Expression [1696]
RIN1 OTPBROUD Strong Altered Expression [1697]
RMDN2 OTK5WSFI Strong Genetic Variation [783]
RMI1 OT1ZVTFL Strong Genetic Variation [1698]
RNASE3 OTVE2XD1 Strong Biomarker [1699]
RNASE4 OTA5SZLC Strong Biomarker [1700]
RNASET2 OTWY64L7 Strong Biomarker [1701]
RNF128 OTJO86CJ Strong Biomarker [620]
RNF19A OTKWCV80 Strong Biomarker [587]
RNF5 OTDQGI37 Strong Altered Expression [1702]
RPL8 OTHMZ1R9 Strong Biomarker [1703]
RPP38 OTOXHKTX Strong Biomarker [285]
RPS2 OTSMTZVB Strong Altered Expression [683]
RPS3 OT0K3TMH Strong Biomarker [1382]
RREB1 OT62460U Strong Biomarker [474]
RTL10 OTHGB81W Strong Biomarker [1704]
RYR2 OT0PF19E Strong Biomarker [1705]
S100A10 OTI71243 Strong Altered Expression [1706]
S100A7 OTJFVJRF Strong Biomarker [1707]
SARS1 OTFKXQ1O Strong Altered Expression [596]
SARS2 OTU4T99W Strong Altered Expression [596]
SCAMP3 OTUNPYCE Strong Biomarker [1708]
SCNN1D OTTX2G9M Strong Altered Expression [1709]
SCO2 OTJQQDRS Strong Biomarker [843]
SCRT1 OTWTE24S Strong Altered Expression [1710]
SDC4 OTKUVUGZ Strong Altered Expression [1711]
SDCBP OTS3NCC5 Strong Biomarker [1712]
SDF4 OTQ7WFYW Strong Biomarker [1501]
SEMA3E OTD4S36H Strong Altered Expression [1713]
SEMA7A OT0ZJK64 Strong Biomarker [1714]
SERPINA3 OT9BP2S0 Strong Altered Expression [1715]
SERPINB9 OTJ811IF Strong Altered Expression [1716]
SESN2 OT889IXY Strong Altered Expression [1717]
SETDB1 OTWVUA1B Strong Biomarker [1718]
SETDB2 OTBVVP9Q Strong Biomarker [1718]
SF1 OTLEDM2S Strong Biomarker [285]
SGMS1 OTZQE7PW Strong Altered Expression [1719]
SGSM3 OTIB1P8A Strong Biomarker [1720]
SHB OTF2HSC0 Strong Biomarker [1721]
SHC1 OT1J5IRN Strong Altered Expression [1681]
SHC4 OTQ0H76H Strong Altered Expression [1681]
SIAH1 OT29A838 Strong Biomarker [1204]
SIGLEC9 OTZC7SIM Strong Altered Expression [1722]
SIPA1 OTXY5RXC Strong Biomarker [285]
SKI OT4KJ8F6 Strong Altered Expression [1723]
SLC35G2 OTFBVS0P Strong Biomarker [1507]
SLFN5 OTT1AESL Strong Altered Expression [1724]
SLIT3 OTU8MKEU Strong Altered Expression [1725]
SMAD4 OTWQWCKG Strong Genetic Variation [1726]
SMARCA1 OT0Y6PTU Strong Altered Expression [1213]
SMIM10 OTISM8ZT Strong Biomarker [1727]
SMUG1 OT2YIOCQ Strong Genetic Variation [1728]
SNAI1 OTDPYAMC Strong Biomarker [1729]
SNAI2 OT7Y8EJ2 Strong Altered Expression [1285]
SNIP1 OTL3RA91 Strong Biomarker [1730]
SOX10 OTF25ULQ Strong Biomarker [1731]
SOX18 OTPUMHWA Strong Biomarker [1732]
SOX6 OTT0W0LE Strong Biomarker [1733]
SOX9 OTVDJFGN Strong Altered Expression [763]
SPAM1 OTMPOB4E Strong Biomarker [1734]
SPANXD OTMM6ANB Strong Biomarker [1437]
SPG7 OT8OY9ST Strong Biomarker [767]
SPINT1 OT1CLR5L Strong Genetic Variation [1735]
SPP2 OTX254AR Strong Genetic Variation [1736]
SPPL2A OTCVF6MM Strong Altered Expression [719]
SPRY2 OTH0CRCZ Strong Altered Expression [1737]
SRGAP2 OTUWFMCQ Strong Altered Expression [1738]
SSX2 OT2Z6RLL Strong Altered Expression [1739]
SSX5 OTNOHH4H Strong Genetic Variation [1740]
ST13 OTNML6UP Strong Biomarker [1514]
ST3GAL4 OTNENJZQ Strong Biomarker [1741]
STAG2 OTR6X1Q7 Strong Biomarker [1223]
STAT2 OTO9G2RZ Strong Biomarker [264]
STIP1 OT7TXLOX Strong Altered Expression [1742]
STN1 OT8UWRA3 Strong Genetic Variation [892]
SUGCT OTA8L0TN Strong Biomarker [1743]
SYT4 OTA1D7VL Strong Biomarker [1744]
TAS2R60 OTZRD883 Strong Biomarker [823]
TBX3 OTM64N7K Strong Altered Expression [1745]
TCF21 OT393IMA Strong Biomarker [1746]
TERF2IP OT3M5P3G Strong Altered Expression [587]
TET2 OTKKT03T Strong Biomarker [1747]
TFPI2 OTZCRWOR Strong Biomarker [1748]
THOC2 OTNXE5G2 Strong Biomarker [1749]
TIMM8A OTDX9687 Strong Biomarker [1405]
TINAGL1 OTZZO56M Strong Biomarker [1750]
TJP1 OTBDCUPK Strong Biomarker [1751]
TLE1 OT50MRZ1 Strong Altered Expression [1752]
TLE3 OTR9PH95 Strong Altered Expression [1753]
TMEM132B OTDSGT9O Strong Biomarker [823]
TMEM30B OTNSBH84 Strong Biomarker [1507]
TMSB10 OTLVZ13T Strong Biomarker [1754]
TNFRSF19 OTTVT4MB Strong Biomarker [1755]
TOP3A OT3CKUI9 Strong Genetic Variation [1756]
TPD52 OTPKSK43 Strong Biomarker [662]
TPM1 OTD73X6R Strong Biomarker [1757]
TPM3 OT5RU5G6 Strong Biomarker [1758]
TPPP2 OTI3WA6X Strong Biomarker [597]
TRAF2 OT1MEZZN Strong Altered Expression [1759]
TRAPPC2L OT1LN60D Strong Biomarker [1733]
TRIM13 OTQIUACB Strong Biomarker [767]
TRIM44 OT0B1T2B Strong Biomarker [1760]
TRIT1 OTCU9FS5 Strong Biomarker [1761]
TRRAP OT68OI2Y Strong Biomarker [823]
TSGA10 OTIF1O1T Strong Altered Expression [1762]
TSHZ1 OTYQ9ECW Strong Genetic Variation [628]
TSPAN8 OT1F68WQ Strong Biomarker [1763]
TTC12 OTDB24YV Strong Biomarker [1764]
ACKR2 OTWYY14H Definitive Biomarker [1765]
ACP1 OTJ9CKLU Definitive Biomarker [1766]
ACTN4 OTCNZAJ5 Definitive Biomarker [1767]
ADGRG1 OTQBB8NT Definitive Biomarker [1768]
AGFG1 OTI8ZKC4 Definitive Altered Expression [1769]
AKAP9 OT7Z2YRP Definitive Genetic Variation [1770]
ANKRD11 OTV0V70M Definitive Genetic Variation [1771]
ANKRD36B OT3MW415 Definitive Biomarker [1772]
ARF6 OTVV7KJO Definitive Biomarker [1773]
ARHGDIB OT9PD6CS Definitive Altered Expression [865]
ARL6IP5 OTYZ6BEQ Definitive Altered Expression [1774]
ATF1 OT251CI0 Definitive Altered Expression [459]
ATF2 OTNIZPEA Definitive Biomarker [1775]
ATOX1 OT05LF59 Definitive Biomarker [1776]
AZIN2 OT8OB7CG Definitive Biomarker [1777]
BAG1 OTRQNIA4 Definitive Biomarker [1778]
BID OTOSHSHU Definitive Biomarker [1779]
BPIFA3 OTCXD1HX Definitive Genetic Variation [1780]
C5AR2 OTP1Q82J Definitive Biomarker [859]
CADM1 OTRWG9QS Definitive Altered Expression [1781]
CCDC80 OTOZSYEM Definitive Altered Expression [1782]
CD63 OT2UGZA9 Definitive Biomarker [1783]
CD68 OTOYEY3J Definitive Biomarker [619]
CD82 OTH8MC64 Definitive Biomarker [1784]
CDCA5 OTZLCQ5U Definitive Altered Expression [1785]
CDH17 OT9EV2XK Definitive Biomarker [1786]
CDK10 OTKP7TTR Definitive Genetic Variation [783]
CDK15 OT8S67QS Definitive Biomarker [340]
CDKAL1 OTA0SGNE Definitive Genetic Variation [783]
CFL1 OTT6D5MH Definitive Biomarker [1787]
CILK1 OTWOYEYP Definitive Biomarker [340]
CIP2A OTVS2GXA Definitive Biomarker [426]
CLEC10A OTD8HQT6 Definitive Altered Expression [1788]
COIL OTP4I4DL Definitive Biomarker [1789]
CXCL5 OTZOUPCA Definitive Altered Expression [1790]
CYLD OT37FKH0 Definitive Biomarker [1791]
DBNDD1 OTATKUA8 Definitive Genetic Variation [1771]
DCAF1 OT3ZDVOE Definitive Altered Expression [1769]
DDX11 OT1WR3MD Definitive Biomarker [912]
DEF8 OTS93PPZ Definitive Genetic Variation [1466]
DNM1L OTXK1Q1G Definitive Biomarker [1060]
ELAVL2 OT6EJ8MQ Definitive Genetic Variation [1792]
EMP2 OTPS2H0L Definitive Biomarker [1793]
ESPN OT7Z6LX2 Definitive Altered Expression [1794]
ETV4 OT8C98UZ Definitive Altered Expression [409]
EWSR1 OT7SRHV3 Definitive Genetic Variation [1255]
FLACC1 OTZN9TZV Definitive Genetic Variation [783]
FLT3LG OTU0YGC4 Definitive Biomarker [1795]
FMNL2 OT9OVWCV Definitive Altered Expression [1796]
FSTL1 OT6KEZUD Definitive Biomarker [1797]
GADL1 OTJM4A0R Definitive Biomarker [1777]
GALNT3 OT7M67WT Definitive Altered Expression [447]
GCNT3 OTQ9ALTR Definitive Altered Expression [1798]
GDF6 OTERXWJU Definitive Biomarker [1221]
GGPS1 OTVEHG28 Definitive Biomarker [878]
GLT8D1 OTG14TPO Definitive Altered Expression [1799]
GOLPH3 OTDLGYM3 Definitive Altered Expression [1800]
GORASP1 OTQS91S7 Definitive Biomarker [1801]
GPR42 OTEB0ROY Definitive Altered Expression [452]
GPX3 OT6PK94R Definitive Altered Expression [1802]
GTF2H1 OTCRXC6B Definitive Altered Expression [226]
GTSE1 OTPP742Z Definitive Altered Expression [1803]
HACE1 OTEZULKD Definitive Biomarker [1804]
HADHB OT4Y1I62 Definitive Biomarker [902]
HAVCR2 OTOL603T Definitive Altered Expression [1805]
HELB OT769EC5 Definitive Biomarker [1806]
HLA-C OTV38BUJ Definitive Biomarker [1807]
HOXB9 OTMVHQOU Definitive Biomarker [1065]
IL3 OT0CQ35N Definitive Biomarker [1808]
IL6ST OT1N9C70 Definitive Biomarker [368]
IRF4 OT1DHQ1P Definitive Altered Expression [1809]
ISYNA1 OT49ONSE Definitive Altered Expression [313]
KAT8 OT5LPQTR Definitive Biomarker [1810]
KL OTD4VWU6 Definitive Biomarker [1811]
KLHDC2 OTBHH882 Definitive Biomarker [1812]
LAMP3 OTN0XL3W Definitive Biomarker [1109]
LGALS9 OT7MF91K Definitive Biomarker [214]
LIN28B OTVWP0FN Definitive Altered Expression [1813]
MAK16 OTD546E5 Definitive Biomarker [390]
MAP2K3 OTI2OREX Definitive Biomarker [1814]
MARCHF1 OTI2EYO6 Definitive Genetic Variation [1815]
MED1 OTOO24C4 Definitive Biomarker [1816]
MFAP1 OTZN4FT3 Definitive Altered Expression [1817]
MIA2 OTOGTUTU Definitive Altered Expression [1121]
MSC OTBRPZL5 Definitive Biomarker [1818]
MVP OTJGHJRB Definitive Biomarker [405]
NCOA5 OTOGWTWB Definitive Genetic Variation [1477]
NFATC2 OTK5T6HZ Definitive Biomarker [1819]
NID1 OTKLBLS6 Definitive Genetic Variation [1820]
NOG OTGRHHPG Definitive Biomarker [1821]
NOVA1 OT6A9KHY Definitive Altered Expression [1555]
NPM2 OT9JSU8L Definitive Biomarker [1822]
OPN1MW OTPJ7LX4 Definitive Biomarker [1823]
OTOR OTA62UQB Definitive Altered Expression [1121]
PARVA OTLKEWRY Definitive Altered Expression [1824]
PBX3 OT8WMVM4 Definitive Biomarker [1825]
PELI1 OTMLBCLC Definitive Altered Expression [1826]
PHF20 OTCBVH5P Definitive Genetic Variation [1827]
PHLPP2 OTXB1OUI Definitive Altered Expression [1157]
PLA1A OT2IXYNX Definitive Altered Expression [1828]
PLXNC1 OTJ5XKYY Definitive Biomarker [1829]
PNO1 OT010GIS Definitive Biomarker [390]
POLR2A OTHJQ1DZ Definitive Biomarker [1830]
PREX2 OTYT1J6J Definitive Genetic Variation [1831]
PRKACG OTKOQYF8 Definitive Biomarker [340]
PRRT2 OTCJUBDO Definitive Altered Expression [792]
PTHLH OTI1JF13 Definitive Biomarker [375]
PTPRA OTZA82J1 Definitive Biomarker [405]
PTTG1 OTIMYS4W Definitive Biomarker [1832]
PYCARD OT67RON3 Definitive Biomarker [439]
RALY OT78NNWY Definitive Genetic Variation [783]
RBMS3 OTFSC9MR Definitive Biomarker [390]
RGS1 OTGXJYMG Definitive Biomarker [916]
RGS7 OTDQA90X Definitive Biomarker [1833]
RNF2 OTFPLOIN Definitive Altered Expression [1834]
RPAIN OTBMXAYK Definitive Altered Expression [1769]
RRAD OTW2O4GD Definitive Biomarker [1835]
RTN3 OTGZ51QF Definitive Biomarker [1778]
SAFB OTGRV2LW Definitive Biomarker [1778]
SCD5 OTSSUQ3Z Definitive Altered Expression [1836]
SDHA OTOJ8QFF Definitive Biomarker [1837]
SELENOK OTKM7N7P Definitive Biomarker [1838]
SEMA6A OTDQ7QAW Definitive Biomarker [1839]
SIL1 OTDI85I5 Definitive Altered Expression [1840]
SNAPC5 OTNCB038 Definitive CausalMutation [1535]
SPATA33 OTU5TYJA Definitive Genetic Variation [1771]
SRRM2 OTSIMMC9 Definitive Biomarker [390]
ST8SIA1 OTGND2YZ Definitive Biomarker [1841]
STAT5B OTZVPEBT Definitive Biomarker [1842]
SYF2 OTY2ZW1H Definitive Genetic Variation [914]
SYT1 OTVTPOI6 Definitive Biomarker [1801]
THBS2 OTXET551 Definitive Biomarker [1843]
TIMP1 OTOXC51H Definitive Altered Expression [1844]
TLK1 OTICTXI8 Definitive Biomarker [340]
TMEM132D OTV6I4Z0 Definitive Biomarker [1845]
TNMD OTHLVA9G Definitive Biomarker [1791]
TP53AIP1 OT1XVNDP Definitive Altered Expression [1846]
TRAF3IP3 OTNG0L8X Definitive Biomarker [1847]
TRIP4 OTA8OASA Definitive Biomarker [1848]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1339 DOT(s)

References

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2 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
6 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 075259.
7 Hydroxyurea FDA Label
8 Imiquimod FDA Label
9 ClinicalTrials.gov (NCT01546571) Study of a Melanoma Vaccine in Stage IIb, IIc, and III Melanoma Patients. U.S. National Institutes of Health.
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6888).
11 A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma. Clin Cancer Res. 2011 Apr 1;17(7):1998-2005.
12 Lapatinib FDA Label
13 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
14 Lovastatin FDA Label
15 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7499).
16 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7335).
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7719).
18 FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761234
19 Romidepsin FDA Label
20 Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.
21 ClinicalTrials.gov (NCT03070392) Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma
22 Temozolomide FDA Label
23 ClinicalTrials.gov (NCT00920582) Protege Encore Study- Clinical Trial of Teplizumab (MGA031) in Children and Adults With Recent-Onset Type 1 Diabetes Mellitus. U.S. National Institutes of Health.
24 ClinicalTrials.gov (NCT01031966) A Pilot Study to Evaluate ZADAXIN's (Thymalfasin) Ability to Enhance Immune Response to the H1N1sw Influenza Vaccine. U.S. National Institutes of Health.
25 Toripalimab: the First Domestic Anti-Tumor PD-1 Antibody in China. Front Immunol. 2022 Jan 12;12:730666.
26 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6495).
27 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8281).
28 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5893).
29 Study of therapy resistance in cancer cells with functional proteome analysis. Clin Chem Lab Med. 2002 Mar;40(3):221-34.
30 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010983)
31 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011670)
32 ClinicalTrials.gov (NCT01578239) A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours. U.S. National Institutes of Health.
33 ClinicalTrials.gov (NCT00052130) Vaccine Therapy for Patients With Stage III Melanoma. U.S. National Institutes of Health.
34 GMK (Progenics Pharmaceuticals). Curr Opin Investig Drugs. 2002 Jan;3(1):159-64.
35 ClinicalTrials.gov (NCT02395172) Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200). U.S. National Institutes of Health.
36 Clinical pipeline report, company report or official report of GlaxoSmithKline.
37 ClinicalTrials.gov (NCT00036816) Vaccine Therapy in Treating Patients With Melanoma of the Eye. U.S. National Institutes of Health.
38 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035277)
39 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7981).
40 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7990).
41 ClinicalTrials.gov (NCT03635983) A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma. U.S. National Institutes of Health.
42 ClinicalTrials.gov (NCT03635983) A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma. U.S. National Institutes of Health.
43 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8269).
44 ClinicalTrials.gov (NCT02967692) A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma (COMBI-i). U.S. National Institutes of Health.
45 ClinicalTrials.gov (NCT02288897) PV-10 Intralesional Injection vs Systemic Chemotherapy for Treatment of Locally Advanced Cutaneous Melanoma. U.S. National Institutes of Health.
46 ClinicalTrials.gov (NCT00005052) Vaccine Therapy in Treating Patients With Primary Stage II Melanoma. U.S. National Institutes of Health.
47 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019204)
48 ClinicalTrials.gov (NCT01933932) Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC (SELECT-1)
49 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
50 Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway.J Med Chem. 2019 Feb 28;62(4):1715-1730.
51 ClinicalTrials.gov (NCT01221870) Tesetaxel as First-line Therapy for Metastatic Breast Cancer. U.S. National Institutes of Health.
52 ClinicalTrials.gov (NCT03445533) A Study of IMO-2125 in Combination With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma (ILLUMINATE-301) (ILLUMINATE-301). U.S. National Institutes of Health.
53 ClinicalTrials.gov (NCT00050388) Phase II Trial of Allovectin-7 for Head and Neck Cancer. U.S. National Institutes of Health.
54 ClinicalTrials.gov (NCT00791492) An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy. U.S. National Institutes of Health.
55 ClinicalTrials.gov (NCT00035828) A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD. U.S. National Institutes of Health.
56 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033476)
57 Critical Care Nephrology, Claudio Ronco,Rinaldo Bellomo,John A. Kellum. Page(444).
58 Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer. J Clin Oncol. 2003 Mar 1;21(5):884-90.
59 Adjuvant vaccination with melanoma antigen-pulsed dendritic cells in stage III melanoma patients. Med Oncol. 2012 Dec;29(4):2966-77.
60 ClinicalTrials.gov (NCT00590824) Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma. U.S. National Institutes of Health.
61 ClinicalTrials.gov (NCT04337931) A Study to Evaluate APX005M in Subjects With Unresectable or Metastatic Melanoma. U.S. National Institutes of Health.
62 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019429)
63 ClinicalTrials.gov (NCT00509496) Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Anti-gp100:154-162 TCR Gene Engineered Lymphocytes. U.S. National Institutes of Health.
64 ClinicalTrials.gov (NCT04526899) Open-label, Randomized Phase II Trial With BNT111 and Cemiplimab in Combination or as Single Agents in Patients With Anti-PD-1-refractory/Relapsed, Unresectable Stage III or IV Melanoma. U.S.National Institutes of Health.
65 ClinicalTrials.gov (NCT03417739) A Phase II Study of BVD-523 in Metastatic Uveal Melanoma. U.S. National Institutes of Health.
66 Clinical pipeline report, company report or official report of AVAX Technologies.
67 ClinicalTrials.gov (NCT00925314) A Study of Transgenic Lymphocyte Immunization (TLI) Against Telomerase in Subjects With Stage III Melanoma. U.S. National Institutes of Health.
68 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
69 ClinicalTrials.gov (NCT00306553) Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients. U.S. National Institutes of Health.
70 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025020)
71 ClinicalTrials.gov (NCT01605162) Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects With Wild Type BRAF Stage IV or Unresectable Stage III Melanoma. U.S. National Institutes of Health.
72 ClinicalTrials.gov (NCT03595683) Pembrolizumab and EDP1503 in Advanced Melanoma. U.S. National Institutes of Health.
73 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022232)
74 ClinicalTrials.gov (NCT00003895) Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma. U.S. National Institutes of Health.
75 ClinicalTrials.gov (NCT02421094) Clinical Study for Non-Invasive Imaging Methods for GR-MD-02 for Treatment of Liver Fibrosis. U.S. National Institutes of Health.
76 ClinicalTrials.gov (NCT02696356) Phase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected Melanoma. U.S. National Institutes of Health.
77 ClinicalTrials.gov (NCT01149343) Evaluation of a New Vaccine Treatment for Patients With Metastatic Skin Cancer. U.S. National Institutes of Health.
78 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013884)
79 Phase I/II trial of Hi8 PrimeBoost therapeutic vaccine in stage III/IV metastatic melanoma. Melanoma Research. 09/2006; 16(Supplement 1).
80 Clinical pipeline report, company report or official report of OncoSec Medical.
81 ClinicalTrials.gov (NCT05050006) A Phase 2, Open-label, Multicenter Study Evaluating the Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes (TILs) in Subjects With Advanced Melanoma (DELTA-1). U.S.National Institutes of Health.
82 ClinicalTrials.gov (NCT00004050) Leuvectin Followed By Surgery in Treating Patients With Stage II or Stage III Prostate Cancer. U.S. National Institutes of Health.
83 ClinicalTrials.gov (NCT02360579) Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma (LN-144). U.S. National Institutes of Health.
84 Clinical pipeline report, company report or official report of MolMed.
85 ClinicalTrials.gov (NCT01026051) Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma. U.S. National Institutes of Health.
86 ClinicalTrials.gov (NCT01425008) Study of MLN2480 in Patients With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion in Patients With Metastatic Melanoma. U.S. National Institutes of Health.
87 ClinicalTrials.gov (NCT01574716) Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation. (SOURCE). U.S. National Institutes of Health.
88 ClinicalTrials.gov (NCT03897881) An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942). U.S. National Institutes of Health.
89 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026542)
90 ClinicalTrials.gov (NCT00003362) Vaccine Therapy Plus Immune Adjuvants in Treating Patients With Advanced Melanoma. U.S. National Institutes of Health.
91 ClinicalTrials.gov (NCT00189332) Use of 852A in Metastatic Cutaneous Melanoma.. U.S. National Institutes of Health.
92 ClinicalTrials.gov (NCT02428712) A Study of PLX8394 as a Single Agent in Patients With Advanced, Unresectable Solid Tumors. U.S. National Institutes of Health.
93 An immuno-oncology company developing a novel polyvalent antigen therapy for the treatment of melanoma. Polynoma. 2015.
94 ClinicalTrials.gov (NCT04577807) LUMINOS-102: PVSRIPO With or Without Immune Checkpoint Blockade in Patients With Advanced PD-1 Refractory Melanoma. U.S. National Institutes of Health.
95 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5674).
96 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800038158)
97 ClinicalTrials.gov (NCT00991250) SentoClone Compared to Reference Treatment in Advanced Malignant Melanoma. U.S. National Institutes of Health.
98 ClinicalTrials.gov (NCT00042783) Vaccine Therapy in Treating Patients With Stage IV Melanoma. U.S. National Institutes of Health.
99 ClinicalTrials.gov (NCT02301611) Phase IIB TL + YCWP + DC in Melanoma. U.S. National Institutes of Health.
100 Clinical pipeline report, company report or official report of Lion biotechnologies.
101 ClinicalTrials.gov (NCT00612664) Phase II, 2nd Line Melanoma - RAND Monotherapy. U.S. National Institutes of Health.
102 ClinicalTrials.gov (NCT04152863) Efficacy, Safety, and Tolerability of V937 Administered Intravenously or Intratumorally With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants With Advanced/Metastatic Melanoma (V937-011). U.S. National Institutes of Health.
103 ClinicalTrials.gov (NCT04291105) Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients. U.S. National Institutes of Health.
104 Clinical pipeline report, company report or official report of ZIOPHARM.
105 A Special Report on Gene Therapy, K. K. Jain. Page(138).
106 ClinicalTrials.gov (NCT04123470) A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma. U.S. National Institutes of Health.
107 ClinicalTrials.gov (NCT04205227) A Phase 1/2A Trial of ENB 003 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors. U.S.National Institutes of Health.
108 ClinicalTrials.gov (NCT03973151) Study of HL-085 in NRAS Mutant Advanced Melanoma. U.S. National Institutes of Health.
109 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024121)
110 Amgen to Acquire BioVex, a Privately Held Biotechnology Company Headquartered in Woburn, Mass
111 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032104)
112 ClinicalTrials.gov (NCT01239134) Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors. U.S. National Institutes of Health.
113 Adoptive T cell therapy for cancer in the clinic. J Clin Invest. 2007 June 1; 117(6): 1466-1476.
114 Phase 1 Clinical Trial Evaluating the Safety and Anti-Tumor Activity of ADP-A2M10 SPEAR T-Cells in Patients With MAGE-A10+ Head and Neck, Melanoma, or Urothelial Tumors. Front Oncol. 2022 Mar 18;12:818679.
115 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037366)
116 Nearly 800 Medicines and Vaccines in Clinical Testing For Cancer Offer New Hope to Patients. Pharmaceutical Research and Manufacturers of America report. 2014.
117 Pre-EMP-tive strike against GBM. SciBX 7(14); doi:10.1038/scibx.2014.389. April 10 2014
118 Clinical pipeline report, company report or official report of Astex Pharmaceuticals.
119 ClinicalTrials.gov (NCT03060356) Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET)
120 ClinicalTrials.gov (NCT03743298) Safety of AV-MEL-1 With Anti-PD-1 Therapy in Metastatic Melanoma. U.S. National Institutes of Health.
121 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3945).
122 ClinicalTrials.gov (NCT02915445) EpCAM CAR-T for Treatment of Nasopharyngeal Carcinoma and Breast Cancer
123 ClinicalTrials.gov (NCT03329950) A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies. U.S. National Institutes of Health.
124 ClinicalTrials.gov (NCT03291002) Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC. U.S. National Institutes of Health.
125 ClinicalTrials.gov (NCT00815607) Trial of an Intratumoral Injections of INXN-3001 in Subjects With Stage III or IV Melanoma. U.S. National Institutes of Health.
126 ClinicalTrials.gov (NCT01522664) A Study of DEDN6526A in Patients With Metastatic or Unresectable Melanoma. U.S. National Institutes of Health.
127 Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells. Science. 2015 May 15;348(6236):803-8.
128 ClinicalTrials.gov (NCT01137006) An Open-Label, Dose-Escalation Study of IMC-20D7S In Patients With Malignant Melanoma. U.S. National Institutes of Health.
129 ClinicalTrials.gov (NCT04596033) TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy. U.S. National Institutes of Health.
130 ClinicalTrials.gov (NCT03649529) Treatment of Malignant Melanoma With GPA-TriMAR-T Cell Therapy
131 ClinicalTrials.gov (NCT01213472) Evaluation of a New Anti-cancer Immunotherapy in Patients With Non-operable and Progressing Metastatic Cutaneous Melanoma. U.S. National Institutes of Health.
132 Phase I trial of IL-2 plasmid DNA with electroporation in metastatic melanoma, Journal of Clinical Oncology, Vol 25, No 18S (June 20 Supplement), 2007: 8578.
133 ClinicalTrials.gov (NCT04370704) Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies. U.S. National Institutes of Health.
134 ClinicalTrials.gov (NCT01397708) Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma. U.S. National Institutes of Health.
135 ClinicalTrials.gov (NCT00747825) Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma. U.S. National Institutes of Health.
136 ClinicalTrials.gov (NCT01052142) Safety Study of a Liposomal Vaccine to Treat Malignant Melanoma. U.S. National Institutes of Health.
137 ClinicalTrials.gov (NCT02122861) A Phase 1 Safety Study of Intradermal ID-LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1. U.S. National Institutes of Health.
138 ClinicalTrials.gov (NCT00471133) Safety and Immunogenicity of a Melanoma DNA Vaccine Delivered by Electroporation. U.S. National Institutes of Health.
139 Journal of Clinical Oncology, 2005 ASCO Annual Meeting Proceedings. Vol 23, No 16S (June 1 Supplement), 2005: 7551.
140 ClinicalTrials.gov (NCT04543188) A TWO-PART, PHASE 1A/B, OPEN-LABEL, MULTICENTER TRIAL EVALUATING PHARMACOKINETICS, SAFETY AND EFFICACY OF PF-07284890 (ARRY 461) IN PARTICIPANTS WITH BRAF V600 MUTANT SOLID TUMORS WITH AND WITHOUT BRAIN INVOLVEMENT. U.S.National Institutes of Health.
141 Clinical pipeline report, company report or official report of GlaxoSmithKline.
142 ClinicalTrials.gov (NCT04543305) A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic Malignancies. U.S. National Institutes of Health.
143 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025308)
144 ClinicalTrials.gov (NCT01727778) Safety and Preliminary Efficacy Study of the Antibody PAT-SM6 in Patients With Relapsed or Refractory Multiple Myeloma. U.S. National Institutes of Health.
145 ClinicalTrials.gov (NCT04096638) Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
146 ClinicalTrials.gov (NCT03161431) SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab. U.S. National Institutes of Health.
147 ClinicalTrials.gov (NCT03385486) Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors. U.S. National Institutes of Health.
148 A phase I study of an allogeneic cell vaccine (VACCIMEL) with GM-CSF in melanoma patients. J Immunother. 2006 Jul-Aug;29(4):444-54.
149 ClinicalTrials.gov (NCT00223899) A Trial to Evaluate the Safety of Intratumoral VCL-IM01 Followed by Electroporation in Metastatic Melanoma. U.S. National Institutes of Health.
150 ClinicalTrials.gov (NCT03517488) A Study of XmAb20717 in Subjects With Selected Advanced Solid Tumors (DUET-2). U.S. National Institutes of Health.
151 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027551)
152 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004320)
153 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004906)
154 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013219)
155 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017393)
156 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014153)
157 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028388)
158 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010286)
159 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008660)
160 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001208)
161 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021775)
162 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016814)
163 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016041)
164 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022593)
165 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035865)
166 2011 Pipeline of Anavex.
167 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008666)
168 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008898)
169 Clinical pipeline report, company report or official report of MediGene AG.
170 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022850)
171 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006527)
172 Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines. Br J Cancer. 2011 Feb 15;104(4):653-63.
173 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
174 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1797).
175 Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. FASEB J. 2010 Nov;24(11):4575-84.
176 Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL). Biomed Res Int. 2013;2013:976383.
177 Clinical pipeline report, company report or official report of novartis.
178 Clinical pipeline report, company report or official report of Roche.
179 Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207.
180 Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.Oncotarget. 2017 Jun 27;8(42):71965-71980. doi: 10.18632/oncotarget.18666. eCollection 2017 Sep 22.
181 Combined effects of GSTP1 and MRP1 in melanoma drug resistance.Br J Cancer. 2005 Jul 25;93(2):216-23. doi: 10.1038/sj.bjc.6602681.
182 Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps.Horm Cancer. 2017 Jun;8(3):143-156. doi: 10.1007/s12672-017-0292-7. Epub 2017 Mar 14.
183 Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors.Clin Cancer Res. 2016 Jan 1;22(1):96-106. doi: 10.1158/1078-0432.CCR-15-0743. Epub 2015 Sep 15.
184 Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis.Oncogene. 2017 Aug 31;36(35):5058-5067. doi: 10.1038/onc.2017.162. Epub 2017 May 29.
185 Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq.Gene. 2016 Oct 30;592(1):86-98. doi: 10.1016/j.gene.2016.07.052. Epub 2016 Jul 25.
186 Long-term follow up of metastatic melanoma patients treated with Thymosin alpha-1: investigating immune checkpoints synergy.Expert Opin Biol Ther. 2018 Jul;18(sup1):77-83. doi: 10.1080/14712598.2018.1494717.
187 3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P(2) modulation.Oncogene. 2020 Jan;39(2):368-384. doi: 10.1038/s41388-019-0993-1. Epub 2019 Sep 2.
188 Enhancement role of host 12/15-lipoxygenase in melanoma progression.Eur J Cancer. 2013 Aug;49(12):2747-59. doi: 10.1016/j.ejca.2013.03.030. Epub 2013 May 8.
189 Characterization of ML-IAP protein stability and physiological role in vivo.Biochem J. 2012 Nov 1;447(3):427-36. doi: 10.1042/BJ20121103.
190 ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis.Oncotarget. 2017 Jul 5;8(44):75778-75796. doi: 10.18632/oncotarget.19018. eCollection 2017 Sep 29.
191 Physico-chemical and Biological Evaluation of Flavonols: Fisetin, Quercetin and Kaempferol Alone and Incorporated in beta Cyclodextrins.Anticancer Agents Med Chem. 2017;17(4):615-626. doi: 10.2174/1871520616666160621105306.
192 Aquaporin-1 inhibition reduces metastatic formation in a mouse model of melanoma.J Cell Mol Med. 2018 Feb;22(2):904-912. doi: 10.1111/jcmm.13378. Epub 2017 Oct 17.
193 Aquaporins mediate the chemoresistance of human melanoma cells to arsenite.Mol Oncol. 2012 Feb;6(1):81-7. doi: 10.1016/j.molonc.2011.11.001. Epub 2011 Nov 13.
194 Decline in arylsulfatase B leads to increased invasiveness of melanoma cells.Oncotarget. 2017 Jan 17;8(3):4169-4180. doi: 10.18632/oncotarget.13751.
195 Translational reprogramming marks adaptation to asparagine restriction in cancer.Nat Cell Biol. 2019 Dec;21(12):1590-1603. doi: 10.1038/s41556-019-0415-1. Epub 2019 Nov 18.
196 ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.Cell Rep. 2017 Mar 7;18(10):2331-2342. doi: 10.1016/j.celrep.2017.02.040.
197 Cancer vaccines.Anticancer Drugs. 1997 Sep;8(8):727-33. doi: 10.1097/00001813-199709000-00001.
198 IGF1 promotes resistance to apoptosis in melanoma cells through an increased expression of BCL2, BCL-X(L), and survivin.J Invest Dermatol. 2008 Jun;128(6):1499-505. doi: 10.1038/sj.jid.5701185. Epub 2007 Dec 13.
199 Combining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.Oncotarget. 2016 Dec 20;7(51):84594-84607. doi: 10.18632/oncotarget.13141.
200 Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-1 expression.Oncotarget. 2017 Jun 27;8(26):42901-42916. doi: 10.18632/oncotarget.17160.
201 Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases.Sci Rep. 2017 Dec 5;7(1):16958. doi: 10.1038/s41598-017-17318-w.
202 Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells.Sci Rep. 2018 Oct 8;8(1):14913. doi: 10.1038/s41598-018-33337-7.
203 Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically.Cancer Immunol Res. 2019 Jul;7(7):1064-1078. doi: 10.1158/2326-6066.CIR-18-0657. Epub 2019 May 14.
204 Ecto-Calreticulin is essential for an efficient immunogenic cell death stimulation in mouse melanoma.Genes Immun. 2019 Jul;20(6):509-513. doi: 10.1038/s41435-018-0047-7. Epub 2018 Oct 4.
205 Withaferin A modulates AIM2 inflammasome and caspase-1 expression in THP-1 polarized macrophages.Exp Cell Res. 2019 Oct 15;383(2):111564. doi: 10.1016/j.yexcr.2019.111564. Epub 2019 Aug 20.
206 Chinese Propolis Exerts Anti-Proliferation Effects in Human Melanoma Cells by Targeting NLRP1 Inflammatory Pathway, Inducing Apoptosis, Cell Cycle Arrest, and Autophagy.Nutrients. 2018 Aug 26;10(9):1170. doi: 10.3390/nu10091170.
207 Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database.J Invest Dermatol. 2015 Apr;135(4):1074-1079. doi: 10.1038/jid.2014.491. Epub 2014 Nov 19.
208 A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.PLoS One. 2018 Apr 4;13(4):e0193461. doi: 10.1371/journal.pone.0193461. eCollection 2018.
209 Long noncoding RNA CPS1-IT1 suppresses melanoma cell metastasis through inhibiting Cyr61 via competitively binding to BRG1.J Cell Physiol. 2019 Dec;234(12):22017-22027. doi: 10.1002/jcp.28764. Epub 2019 May 20.
210 Cyanidin-3-o-Glucoside Pharmacologically Inhibits Tumorigenesis via Estrogen Receptor in Melanoma Mice.Front Oncol. 2019 Oct 22;9:1110. doi: 10.3389/fonc.2019.01110. eCollection 2019.
211 WD repeat and SOCS box containing protein 2 in the proliferation, cycle progression, and migration of melanoma cells.Biomed Pharmacother. 2019 Aug;116:108974. doi: 10.1016/j.biopha.2019.108974. Epub 2019 May 16.
212 CCR4 is a determinant of melanoma brain metastasis.Oncotarget. 2017 May 9;8(19):31079-31091. doi: 10.18632/oncotarget.16076.
213 High expression of CCR5 in melanoma enhances epithelial-mesenchymal transition and metastasis via TGF1.J Pathol. 2019 Apr;247(4):481-493. doi: 10.1002/path.5207. Epub 2019 Jan 16.
214 Accumulation of Circulating CCR7(+) Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway.Cancer Immunol Res. 2019 May;7(5):841-852. doi: 10.1158/2326-6066.CIR-18-0651. Epub 2019 Apr 2.
215 Current status of chimeric antigen receptor engineered T cell-based and immune checkpoint blockade-based cancer immunotherapies.Cancer Immunol Immunother. 2017 Sep;66(9):1113-1121. doi: 10.1007/s00262-017-2007-x. Epub 2017 May 11.
216 The antibody-drug conjugate target landscape across a broad range of tumour types.Ann Oncol. 2017 Dec 1;28(12):3083-3091. doi: 10.1093/annonc/mdx541.
217 Identification of CD24 as a marker for tumorigenesis of melanoma.Onco Targets Ther. 2018 Jun 12;11:3401-3406. doi: 10.2147/OTT.S157043. eCollection 2018.
218 Tailoring early-phase clinical trial design to address multiple research objectives.Cancer Immunol Immunother. 2020 Jan;69(1):95-102. doi: 10.1007/s00262-019-02442-5. Epub 2019 Dec 5.
219 Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients.J Transl Med. 2017 Apr 20;15(1):79. doi: 10.1186/s12967-017-1182-z.
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221 Macrophage migration inhibitory factor-CD74 interaction regulates the expression of programmed cell death ligand 1 in melanoma cells.Cancer Sci. 2019 Jul;110(7):2273-2283. doi: 10.1111/cas.14038. Epub 2019 May 29.
222 Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation.Front Immunol. 2017 Mar 29;8:358. doi: 10.3389/fimmu.2017.00358. eCollection 2017.
223 Expression and function of CD9 in melanoma cells.Mol Carcinog. 2010 Jan;49(1):85-93. doi: 10.1002/mc.20580.
224 Lycorine hydrochloride inhibits metastatic melanoma cell-dominant vasculogenic mimicry.Pigment Cell Melanoma Res. 2012 Sep;25(5):630-8. doi: 10.1111/j.1755-148X.2012.01036.x.
225 CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma.Cancer Res. 2018 Dec 1;78(23):6561-6574. doi: 10.1158/0008-5472.CAN-18-0330. Epub 2018 Oct 8.
226 Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair.Oncogene. 2019 May;38(19):3616-3635. doi: 10.1038/s41388-018-0661-x. Epub 2019 Jan 16.
227 CDKL1 promotes tumor proliferation and invasion in colorectal cancer.Onco Targets Ther. 2017 Mar 16;10:1613-1624. doi: 10.2147/OTT.S133014. eCollection 2017.
228 CEA-negative glioblastoma and melanoma cells are sensitive to cytosine deaminase/5-fluorocytosine therapy directed by the carcinoembryonic antigen promoter.Acta Biochim Pol. 2004;51(3):723-32.
229 Suppression of cFLIPL promotes JNK activation in malignant melanoma cells.Mol Med Rep. 2016 Mar;13(3):2904-8. doi: 10.3892/mmr.2016.4856. Epub 2016 Feb 3.
230 Synergistic Effects of Melittin and Plasma Treatment: A Promising Approach for Cancer Therapy.Cancers (Basel). 2019 Aug 3;11(8):1109. doi: 10.3390/cancers11081109.
231 The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4.Cell Cycle. 2016 Jun 2;15(11):1462-70. doi: 10.1080/15384101.2016.1175258. Epub 2016 Apr 22.
232 GNA14 silencing suppresses the proliferation of endometrial carcinoma cells through inducing apoptosis and G(2)/M cell cycle arrest.Biosci Rep. 2018 Sep 7;38(5):BSR20180574. doi: 10.1042/BSR20180574. Print 2018 Oct 31.
233 Hexokinase2 controls angiogenesis in melanoma by promoting aerobic glycolysis and activating the p38-MAPK signaling.J Cell Biochem. 2019 Dec;120(12):19721-19729. doi: 10.1002/jcb.29278. Epub 2019 Jul 3.
234 Activation of cancer-associated fibroblasts is required for tumor neovascularization in a murine model of melanoma.Matrix Biol. 2018 Dec;74:52-61. doi: 10.1016/j.matbio.2018.06.003. Epub 2018 Jun 7.
235 NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG.PLoS One. 2016 Apr 5;11(4):e0153181. doi: 10.1371/journal.pone.0153181. eCollection 2016.
236 T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.Sci Transl Med. 2018 Apr 11;10(436):eaan3311. doi: 10.1126/scitranslmed.aan3311.
237 Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study.Mol Cancer. 2010 Aug 4;9:207. doi: 10.1186/1476-4598-9-207.
238 Cytoskeleton and ECM tumor mutant peptides: Increased protease sensitivities and potential consequences for the HLA class I mutant epitope reservoir.Int J Cancer. 2018 Mar 1;142(5):988-998. doi: 10.1002/ijc.31111. Epub 2017 Nov 2.
239 Cathepsin K expression in melanoma is associated with metastases.Histol Histopathol. 2017 Jul;32(7):711-716. doi: 10.14670/HH-11-833. Epub 2016 Oct 7.
240 Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment.Oncotarget. 2017 Feb 28;8(9):14428-14442. doi: 10.18632/oncotarget.14803.
241 Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model.Oncoimmunology. 2018 Apr 18;7(8):e1450715. doi: 10.1080/2162402X.2018.1450715. eCollection 2018.
242 Uveal Melanomas Harbor Recurrent Activating Mutations in CYSLTR2.Cancer Discov. 2016 Jun;6(6):573. doi: 10.1158/2159-8290.CD-RW2016-084. Epub 2016 May 5.
243 Directed phenotype switching as an effective antimelanoma strategy.Cancer Cell. 2013 Jul 8;24(1):105-19. doi: 10.1016/j.ccr.2013.05.009. Epub 2013 Jun 20.
244 Dihydroorotate dehydrogenase Inhibitors Target c-Myc and Arrest Melanoma, Myeloma and Lymphoma cells at S-phase.J Cancer. 2017 Sep 5;8(15):3086-3098. doi: 10.7150/jca.14835. eCollection 2017.
245 Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotype.PLoS One. 2014 Apr 14;9(4):e95157. doi: 10.1371/journal.pone.0095157. eCollection 2014.
246 Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.Oncoimmunology. 2017 Feb 10;6(3):e1290035. doi: 10.1080/2162402X.2017.1290035. eCollection 2017.
247 A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma.Melanoma Res. 2019 Dec;29(6):582-589. doi: 10.1097/CMR.0000000000000640.
248 Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation.Front Biosci. 2008 Jan 1;13:2435-43. doi: 10.2741/2856.
249 Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.EBioMedicine. 2016 Aug;10:85-100. doi: 10.1016/j.ebiom.2016.06.023. Epub 2016 Jun 16.
250 RIG-I inhibits the MAPK-dependent proliferation of BRAF mutant melanoma cells via MKP-1.Cell Signal. 2016 May;28(5):335-347. doi: 10.1016/j.cellsig.2016.01.012. Epub 2016 Jan 29.
251 PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.PLoS Genet. 2016 Dec 15;12(12):e1006518. doi: 10.1371/journal.pgen.1006518. eCollection 2016 Dec.
252 GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment.Sci Immunol. 2019 Dec 13;4(42):eaax8189. doi: 10.1126/sciimmunol.aax8189.
253 Hu antigen R (HuR) heterogeneous expression quantification as a prognostic marker of melanoma.J Cutan Pathol. 2018 May;45(5):333-336. doi: 10.1111/cup.13119. Epub 2018 Feb 23.
254 Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC.Cancer Immunol Res. 2017 May;5(5):417-424. doi: 10.1158/2326-6066.CIR-16-0325. Epub 2017 Apr 14.
255 MicroRNA-363-3p/p21(Cip1/Waf1) axis is regulated by HIF-2 in mediating stemness of melanoma cells.Neoplasma. 2019 May 23;66(3):427-436. doi: 10.4149/neo_2018_180828N655.
256 Curcumin-loaded nanoemulsion: a new safe and effective formulation to prevent tumor reincidence and metastasis.Nanoscale. 2018 Dec 21;10(47):22612-22622. doi: 10.1039/c8nr06173d. Epub 2018 Nov 28.
257 Recombinant human erythropoietin stimulates melanoma tumor growth through activation of initiation factor eIF4E.Oncotarget. 2017 May 2;8(18):30317-30327. doi: 10.18632/oncotarget.16331.
258 IRE1 Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8(+) T Cell Priming.Front Immunol. 2019 Jan 4;9:3050. doi: 10.3389/fimmu.2018.03050. eCollection 2018.
259 ERR Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1-Elevated Melanomas.Mol Cancer Res. 2017 Oct;15(10):1366-1375. doi: 10.1158/1541-7786.MCR-17-0143. Epub 2017 Jun 8.
260 Ezrin mediates both HGF/Met autocrine and non-autocrine signaling-induced metastasis in melanoma.Int J Cancer. 2018 Apr 15;142(8):1652-1663. doi: 10.1002/ijc.31196. Epub 2017 Dec 15.
261 The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma.J Exp Med. 2017 Feb;214(2):339-358. doi: 10.1084/jem.20160596. Epub 2017 Jan 17.
262 Integrated case-control and somatic-germline interaction analyses of melanoma susceptibility genes.Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2247-2254. doi: 10.1016/j.bbadis.2018.01.007. Epub 2018 Jan 6.
263 Fatty Acid Synthase and Acetyl-CoA Carboxylase Are Expressed in Nodal Metastatic Melanoma But Not in Benign Intracapsular Nodal Nevi.Am J Dermatopathol. 2018 Apr;40(4):259-264. doi: 10.1097/DAD.0000000000000939.
264 FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation.Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):584-594. doi: 10.1073/pnas.1909879116. Epub 2019 Dec 16.
265 Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.J Clin Invest. 2017 Jun 1;127(6):2310-2325. doi: 10.1172/JCI91291. Epub 2017 May 2.
266 G protein-coupled receptor 40 expression in human melanoma - correlation with tumour thickness, AJCC stage and survival.J Eur Acad Dermatol Venereol. 2020 Feb;34(2):285-292. doi: 10.1111/jdv.15924. Epub 2019 Oct 31.
267 Fatty acid receptor GPR120: a novel marker for human melanoma.Melanoma Res. 2018 Aug;28(4):271-276. doi: 10.1097/CMR.0000000000000445.
268 BRAF inhibition causes resilience of melanoma cell lines by inducing the secretion of FGF1.Oncogenesis. 2018 Sep 20;7(9):71. doi: 10.1038/s41389-018-0082-2.
269 CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells.Sci Rep. 2018 Aug 8;8(1):11893. doi: 10.1038/s41598-018-30338-4.
270 FOXQ1 controls the induced differentiation of melanocytic cells.Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y. Epub 2018 Feb 20.
271 Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells.J Exp Clin Cancer Res. 2017 Dec 8;36(1):180. doi: 10.1186/s13046-017-0650-x.
272 Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway.Cell Commun Signal. 2018 Jul 3;16(1):37. doi: 10.1186/s12964-018-0250-1.
273 MicroRNA-485-5p represses melanoma cell invasion and proliferation by suppressing Frizzled7.Biomed Pharmacother. 2017 Jun;90:303-310. doi: 10.1016/j.biopha.2017.03.064. Epub 2017 Mar 30.
274 Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma.Cancers (Basel). 2019 Sep 12;11(9):1352. doi: 10.3390/cancers11091352.
275 The influence of oral tumor cell proliferation activity and membrane potential on the transfection efficiency of a cationic liposome.Oncol Rep. 2005 Dec;14(6):1487-91.
276 Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.Pathol Oncol Res. 2019 Oct;25(4):1319-1325. doi: 10.1007/s12253-017-0371-7. Epub 2017 Dec 5.
277 Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma.Oncotarget. 2013 Oct;4(10):1721-8. doi: 10.18632/oncotarget.1379.
278 miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma.Mol Carcinog. 2018 Nov;57(11):1566-1576. doi: 10.1002/mc.22878. Epub 2018 Aug 14.
279 Next-Generation Cancer Immunotherapy Targeting Glypican-3.Front Oncol. 2019 Apr 10;9:248. doi: 10.3389/fonc.2019.00248. eCollection 2019.
280 NFATc2 is an intrinsic regulator of melanoma dedifferentiation.Oncogene. 2016 Jun 2;35(22):2862-72. doi: 10.1038/onc.2015.355. Epub 2015 Sep 21.
281 Identification of patients at risk of metastasis using a prognostic 31-gene expression profile in subpopulations of melanoma patients with favorable outcomes by standard criteria.J Am Acad Dermatol. 2019 Jan;80(1):149-157.e4. doi: 10.1016/j.jaad.2018.07.028. Epub 2018 Aug 4.
282 Gelsolin affects the migratory ability of human colon adenocarcinoma and melanoma cells.Life Sci. 2012 Jun 6;90(21-22):851-61. doi: 10.1016/j.lfs.2012.03.039. Epub 2012 Apr 19.
283 Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.Free Radic Biol Med. 2018 Dec;129:256-267. doi: 10.1016/j.freeradbiomed.2018.07.025. Epub 2018 Aug 4.
284 Dendritic cell-based vaccination: powerful resources of immature dendritic cells against pancreatic adenocarcinoma.Oncoimmunology. 2018 Sep 25;7(12):e1504727. doi: 10.1080/2162402X.2018.1504727. eCollection 2018.
285 Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.Oncotarget. 2012 Apr;3(4):399-413. doi: 10.18632/oncotarget.473.
286 Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma.Cancer Discov. 2019 Apr;9(4):469-471. doi: 10.1158/2159-8290.CD-19-0069.
287 Real-time RT-PCR analysis of human histidine decarboxylase, a new marker for several types of leukemia and cancer.Oncol Rep. 2006 Jan;15(1):193-7.
288 Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.Mol Cell. 2016 Apr 7;62(1):34-46. doi: 10.1016/j.molcel.2016.03.013.
289 HLA class II polymorphisms in Spanish melanoma patients: homozygosity for HLA-DQA1 locus can be a potential melanoma risk factor.Br J Dermatol. 2006 Feb;154(2):261-6. doi: 10.1111/j.1365-2133.2005.06896.x.
290 SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma.Appl Immunohistochem Mol Morphol. 2018 Jan;26(1):40-45. doi: 10.1097/PAI.0000000000000500.
291 Loss of SR-BI Down-Regulates MITF and Suppresses Extracellular Vesicle Release in Human Melanoma.Int J Mol Sci. 2019 Mar 1;20(5):1063. doi: 10.3390/ijms20051063.
292 Characterisation of the cancer-associated glucocorticoid system: key role of 11-hydroxysteroid dehydrogenase type 2.Br J Cancer. 2017 Sep 26;117(7):984-993. doi: 10.1038/bjc.2017.243. Epub 2017 Aug 10.
293 Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase.Mol Cell. 2019 Nov 21;76(4):546-561.e8. doi: 10.1016/j.molcel.2019.08.021. Epub 2019 Sep 24.
294 Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases.Melanoma Res. 2005 Aug;15(4):235-44. doi: 10.1097/00008390-200508000-00002.
295 Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.Mol Cell Biol. 2017 Aug 28;37(18):e00061-17. doi: 10.1128/MCB.00061-17. Print 2017 Sep 15.
296 Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.Mol Oncol. 2017 Jun;11(6):599-611. doi: 10.1002/1878-0261.12042. Epub 2017 May 8.
297 Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.Cell Death Dis. 2012 Aug 16;3(8):e371. doi: 10.1038/cddis.2012.108.
298 Cell surface chondroitin sulphate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulphate proteoglycan, perlecan, and is involved in cell adhesion.J Biochem. 2018 May 1;163(5):399-412. doi: 10.1093/jb/mvy008.
299 Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.Clin Cancer Res. 2018 Nov 15;24(22):5685-5696. doi: 10.1158/1078-0432.CCR-18-0554. Epub 2018 Jul 31.
300 Expression of Id-1 is regulated by MCAM/MUC18: a missing link in melanoma progression.Cancer Res. 2011 May 15;71(10):3494-504. doi: 10.1158/0008-5472.CAN-10-3555. Epub 2011 Apr 5.
301 Mps1 is associated with the BRAF(V600E) mutation and predicts poor outcome in patients with colorectal cancer.Oncol Lett. 2019 Mar;17(3):2809-2817. doi: 10.3892/ol.2019.9924. Epub 2019 Jan 14.
302 Antitumor Activity of BRAF Inhibitor and IFN Combination in BRAF-Mutant Melanoma.J Natl Cancer Inst. 2016 Feb 5;108(7):djv435. doi: 10.1093/jnci/djv435. Print 2016 Jul.
303 Tanapoxvirus lacking the 15L gene inhibits melanoma cell growth in vitro by inducing interferon-1 release.Virus Genes. 2017 Jun;53(3):477-482. doi: 10.1007/s11262-017-1434-2. Epub 2017 Feb 10.
304 IGFBP-3 inhibits Wnt signaling in metastatic melanoma cells.Mol Carcinog. 2017 Feb;56(2):681-693. doi: 10.1002/mc.22525. Epub 2016 Jul 27.
305 Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKK inhibition.Redox Biol. 2017 Apr;11:562-576. doi: 10.1016/j.redox.2017.01.010. Epub 2017 Jan 12.
306 Interleukin-13 receptor 2 is a novel marker and potential therapeutic target for human melanoma.Sci Rep. 2019 Feb 4;9(1):1281. doi: 10.1038/s41598-019-39018-3.
307 Apoptosis related protein-1 triggers melanoma cell death via interaction with the juxtamembrane region of p75 neurotrophin receptor.J Cell Mol Med. 2012 Feb;16(2):349-61. doi: 10.1111/j.1582-4934.2011.01304.x.
308 Interleukin 32 expression in human melanoma.J Transl Med. 2019 Apr 5;17(1):113. doi: 10.1186/s12967-019-1862-y.
309 Non-genetic engineering of cytotoxic T cells to target IL-4 receptor enhances tumor homing and therapeutic efficacy against melanoma.Biomaterials. 2018 Mar;159:161-173. doi: 10.1016/j.biomaterials.2018.01.013. Epub 2018 Jan 8.
310 T(H)9 cells in anti-tumor immunity.Semin Immunopathol. 2017 Jan;39(1):39-46. doi: 10.1007/s00281-016-0599-4. Epub 2016 Nov 10.
311 Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma.Medchemcomm. 2017 Jan 1;8(1):88-95. doi: 10.1039/C6MD00466K. Epub 2016 Oct 27.
312 Closed system RT-qPCR as a potential companion diagnostic test for immunotherapy outcome in metastatic melanoma.J Immunother Cancer. 2019 Sep 18;7(1):254. doi: 10.1186/s40425-019-0731-9.
313 Agaricus blazei Murill Polysaccharides Protect Against Cadmium-Induced Oxidative Stress and Inflammatory Damage in Chicken Spleens.Biol Trace Elem Res. 2018 Jul;184(1):247-258. doi: 10.1007/s12011-017-1189-6. Epub 2017 Oct 14.
314 Integrin VLA-4 enhances sialyl-Lewisx/a-negative melanoma adhesion to and extravasation through the endothelium under low flow conditions.Am J Physiol Cell Physiol. 2008 Sep;295(3):C701-7. doi: 10.1152/ajpcell.00245.2008. Epub 2008 Jul 16.
315 Integrin genes and susceptibility to human melanoma.Mutagenesis. 2012 May;27(3):367-73. doi: 10.1093/mutage/ger090. Epub 2011 Dec 20.
316 Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma.Cancer Res. 2019 Mar 15;79(6):1113-1123. doi: 10.1158/0008-5472.CAN-18-1722. Epub 2019 Jan 23.
317 LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro.BMC Cancer. 2012 Oct 5;12:455. doi: 10.1186/1471-2407-12-455.
318 Acquired IFN resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.Nat Commun. 2017 May 31;8:15440. doi: 10.1038/ncomms15440.
319 The small conductance calcium-activated potassium channel 3 (SK3) is a molecular target for Edelfosine to reduce the invasive potential of urothelial carcinoma cells.Tumour Biol. 2016 May;37(5):6275-83. doi: 10.1007/s13277-015-4509-5. Epub 2015 Nov 30.
320 Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.Melanoma Res. 2018 Oct;28(5):380-389. doi: 10.1097/CMR.0000000000000473.
321 H3K27 Demethylase JMJD3 Employs the NF-B and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis.Cancer Res. 2016 Jan 1;76(1):161-70. doi: 10.1158/0008-5472.CAN-15-0536.
322 An immunohistochemical study of NFE2L2, KEAP1 and 8-hydroxy-2'-deoxyguanosine and the EMT markers SNAI2, ZEB1 and TWIST1 in metastatic melanoma.Histol Histopathol. 2017 Feb;32(2):129-136. doi: 10.14670/HH-11-778. Epub 2016 May 12.
323 p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.Cancer Cell. 2019 Jan 14;35(1):46-63.e10. doi: 10.1016/j.ccell.2018.11.008. Epub 2018 Dec 20.
324 Associations between sun sensitive pigmentary genes and serum prostate specific antigen levels.PLoS One. 2018 Mar 8;13(3):e0193893. doi: 10.1371/journal.pone.0193893. eCollection 2018.
325 Kallikrein-related peptidase 7 overexpression in melanoma cells modulates cell adhesion leading to a malignant phenotype.Biol Chem. 2018 Sep 25;399(9):1099-1105. doi: 10.1515/hsz-2017-0339.
326 Shifting the Balance of Activating and Inhibitory Natural Killer Receptor Ligands on BRAF(V600E) Melanoma Lines with Vemurafenib.Cancer Immunol Res. 2017 Jul;5(7):582-593. doi: 10.1158/2326-6066.CIR-16-0380. Epub 2017 Jun 2.
327 Expression of lymphocyte-activating gene 3 and T-cell immunoreceptor with immunoglobulin and ITIM domains in cutaneous melanoma and their correlation with programmed cell death 1 expression in tumor-infiltrating lymphocytes.J Am Acad Dermatol. 2019 Jul;81(1):219-227. doi: 10.1016/j.jaad.2019.03.012. Epub 2019 Mar 14.
328 Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types.J Natl Cancer Inst. 2016 Jun 22;108(11):djw144. doi: 10.1093/jnci/djw144. Print 2016 Nov.
329 Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells.J Biol Chem. 2017 Sep 1;292(35):14413-14424. doi: 10.1074/jbc.M117.776138. Epub 2017 Jun 19.
330 Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration and invasion.Biochem Pharmacol. 2017 Aug 15;138:31-48. doi: 10.1016/j.bcp.2017.05.004. Epub 2017 May 10.
331 Endothelial Rab7 GTPase mediates tumor growth and metastasis in lysosomal acid lipase-deficient mice.J Biol Chem. 2017 Nov 24;292(47):19198-19208. doi: 10.1074/jbc.M116.773093. Epub 2017 Sep 18.
332 miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3-Binding Domain to Regulate Wnt1.Mol Cancer Res. 2019 Jan;17(1):299-309. doi: 10.1158/1541-7786.MCR-18-0460. Epub 2018 Sep 28.
333 Involvement of LPA receptor-5 in the enhancement of cell motile activity by phorbol ester and anticancer drug treatments in melanoma A375cells.Biochem Biophys Res Commun. 2018 Jan 29;496(1):225-230. doi: 10.1016/j.bbrc.2018.01.030. Epub 2018 Jan 5.
334 Interaction of two antitumor peptides with membrane lipids - Influence of phosphatidylserine and cholesterol on specificity for melanoma cells.PLoS One. 2019 Jan 25;14(1):e0211187. doi: 10.1371/journal.pone.0211187. eCollection 2019.
335 Antibody response against cancer-testis antigens MAGEA4 and MAGEA10 in patients with melanoma.Oncol Lett. 2018 Jul;16(1):211-218. doi: 10.3892/ol.2018.8684. Epub 2018 May 10.
336 MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.Clin Cancer Res. 2003 Mar;9(3):947-54.
337 Effects of CT-Xp gene knock down in melanoma cell lines.Oncotarget. 2013 Apr;4(4):531-41. doi: 10.18632/oncotarget.921.
338 MALT1 promotes melanoma progression through JNK/c-Jun signaling.Oncogenesis. 2017 Jul 31;6(7):e365. doi: 10.1038/oncsis.2017.68.
339 A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.Cancer Res. 2019 May 1;79(9):2352-2366. doi: 10.1158/0008-5472.CAN-18-2711. Epub 2019 Feb 28.
340 Long-term Survival of Stage IV Melanoma Patients Treated with BOLD Combination Chemotherapy and Intermediate-dose Subcutaneous Interferon-alpha.Anticancer Res. 2018 Nov;38(11):6393-6397. doi: 10.21873/anticanres.12999.
341 TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma.Cell Death Differ. 2019 Dec;26(12):2520-2534. doi: 10.1038/s41418-019-0315-8. Epub 2019 Mar 8.
342 Clinical genome sequencing uncovers potentially targetable truncations and fusions of MAP3K8 in spitzoid and other melanomas.Nat Med. 2019 Apr;25(4):597-602. doi: 10.1038/s41591-019-0373-y. Epub 2019 Mar 4.
343 The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis--a possible therapeutic target.Oncotarget. 2011 Jan-Feb;2(1-2):8-17. doi: 10.18632/oncotarget.211.
344 Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas.Mol Cancer Ther. 2019 Feb;18(2):289-300. doi: 10.1158/1535-7163.MCT-17-1141. Epub 2018 Nov 27.
345 Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.Nature. 2017 Jun 28;546(7660):676-680. doi: 10.1038/nature22977.
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474 Fluorescence In Situ Hybridization for Melanoma Diagnosis: A Review and a Reappraisal.Am J Dermatopathol. 2016 Apr;38(4):253-69. doi: 10.1097/DAD.0000000000000380.
475 Notch4 Signaling Induces a Mesenchymal-Epithelial-like Transition in Melanoma Cells to Suppress Malignant Behaviors.Cancer Res. 2016 Apr 1;76(7):1690-7. doi: 10.1158/0008-5472.CAN-15-1722. Epub 2016 Jan 22.
476 NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.Cancer Res. 2015 Jul 1;75(13):2708-15. doi: 10.1158/0008-5472.CAN-13-3209. Epub 2015 Apr 1.
477 The effect of fenofibrate, a PPAR activator on toll-like receptor-4 signal transduction in melanoma both in vitro and in vivo.Clin Transl Oncol. 2020 Apr;22(4):486-494. doi: 10.1007/s12094-019-02150-7. Epub 2019 Jun 7.
478 Conformation-dependent binding of a Tetrastatin peptide to (v)(3) integrin decreases melanoma progression through FAK/PI(3)K/Akt pathway inhibition.Sci Rep. 2018 Jun 29;8(1):9837. doi: 10.1038/s41598-018-28003-x.
479 A potential function of RLIP76 in the ovarian corpus luteum.J Ovarian Res. 2019 Apr 18;12(1):34. doi: 10.1186/s13048-019-0510-8.
480 Molecular genetics and targeted therapy of WNT-related human diseases (Review).Int J Mol Med. 2017 Sep;40(3):587-606. doi: 10.3892/ijmm.2017.3071. Epub 2017 Jul 19.
481 Anti-tumor effects of resveratrol on malignant melanoma is associated with promoter demethylation of RUNX3 gene.Pharmazie. 2019 Mar 1;74(3):163-167. doi: 10.1691/ph.2019.8838.
482 MicroRNA-373 promotes cell migration via targeting salt-inducible kinase 1 expression in melanoma.Exp Ther Med. 2018 Dec;16(6):4759-4764. doi: 10.3892/etm.2018.6784. Epub 2018 Sep 21.
483 Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16.Cell Death Dis. 2018 Dec 5;9(12):1179. doi: 10.1038/s41419-018-1221-6.
484 Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis.Cell Physiol Biochem. 2016;38(1):1-14. doi: 10.1159/000438604. Epub 2016 Jan 8.
485 Acute symptomatic hypocalcemia from immune checkpoint therapy-induced hypoparathyroidism.Am J Emerg Med. 2017 Jul;35(7):1039.e5-1039.e7. doi: 10.1016/j.ajem.2017.02.048. Epub 2017 Feb 27.
486 Novel immune signatures associated with dysplastic naevi and primary cutaneous melanoma in human skin.Exp Dermatol. 2019 Jan;28(1):35-44. doi: 10.1111/exd.13805. Epub 2018 Dec 21.
487 Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies.Oncotarget. 2016 Oct 11;7(41):66569-66585. doi: 10.18632/oncotarget.11892.
488 Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk.Int J Cancer. 2015 Oct 15;137(8):1901-1909. doi: 10.1002/ijc.29570. Epub 2015 May 26.
489 Tie2-dependent deletion of 6 integrin subunit in mice reduces tumor growth and angiogenesis.Int J Oncol. 2014 Nov;45(5):2058-64. doi: 10.3892/ijo.2014.2631. Epub 2014 Sep 1.
490 Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy.ACS Nano. 2019 Nov 26;13(11):12671-12686. doi: 10.1021/acsnano.9b04207. Epub 2019 Oct 11.
491 Sensitization of Melanoma Cells for Death Ligand TRAIL Is Based on Cell Cycle Arrest, ROS Production, and Activation of Proapoptotic Bcl-2 Proteins.J Invest Dermatol. 2015 Nov;135(11):2794-2804. doi: 10.1038/jid.2015.250. Epub 2015 Jul 2.
492 Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models.Clin Cancer Res. 2015 Dec 1;21(23):5338-48. doi: 10.1158/1078-0432.CCR-15-0293. Epub 2015 Jul 7.
493 Targeting of TRX2 by miR-330-3p in melanoma inhibits proliferation.Biomed Pharmacother. 2018 Nov;107:1020-1029. doi: 10.1016/j.biopha.2018.08.058. Epub 2018 Aug 24.
494 Genome-wide characterization of circulating tumor cells identifies novel prognostic genomic alterations in systemic melanoma metastasis.Clin Chem. 2014 Jun;60(6):873-85. doi: 10.1373/clinchem.2013.213611. Epub 2014 Apr 9.
495 Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells.Int J Cancer. 2005 Jun 20;115(3):393-402. doi: 10.1002/ijc.20899.
496 Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment.Cancer Res. 2014 Dec 15;74(24):7250-9. doi: 10.1158/0008-5472.CAN-13-3583. Epub 2014 Nov 6.
497 Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma.PLoS One. 2016 Aug 1;11(8):e0160348. doi: 10.1371/journal.pone.0160348. eCollection 2016.
498 -Methylacyl-coenzyme A racemase (AMACR, p504s) is a marker to distinguish malignant melanomas from dysplastic nevi and melanocytic nevi.Tumour Biol. 2014 Dec;35(12):12015-20. doi: 10.1007/s13277-014-2500-1. Epub 2014 Aug 24.
499 Basic fibroblast growth factor affects the expression of angiogenin and cell proliferation in A375 human melanoma cells.Tumori. 2011 Jan-Feb;97(1):95-103. doi: 10.1177/030089161109700117.
500 Increased caspase-2 activity is associated with induction of apoptosis in IFN-beta sensitive melanoma cell lines.J Interferon Cytokine Res. 2010 May;30(5):349-57. doi: 10.1089/jir.2009.0015.
501 Role of the cystathionine lyase/hydrogen sulfide pathway in human melanoma progression.Pigment Cell Melanoma Res. 2015 Jan;28(1):61-72. doi: 10.1111/pcmr.12312. Epub 2014 Oct 6.
502 Intraocular activation of angiogenic and inflammatory pathways in uveal melanoma.Retina. 2012 Jul;32(7):1373-84. doi: 10.1097/IAE.0b013e318239e299.
503 CCR9 homes metastatic melanoma cells to the small bowel.Clin Cancer Res. 2008 Feb 1;14(3):621-3. doi: 10.1158/1078-0432.CCR-07-2235.
504 Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.Peptides. 2016 Sep;83:8-15. doi: 10.1016/j.peptides.2016.07.004. Epub 2016 Jul 22.
505 Immune modulation by melanoma and ovarian tumor cells through expression of the immunosuppressive molecule CD200.Cancer Immunol Immunother. 2008 Jul;57(7):987-96. doi: 10.1007/s00262-007-0429-6.
506 Recombinant transmembrane CD59 (CD59-TM) confers complement resistance to GPI-anchored protein defective melanoma cells.J Cell Physiol. 2002 Feb;190(2):200-6. doi: 10.1002/jcp.10050.
507 Epigenetic disruption of cadherin-11 in human cancer metastasis.J Pathol. 2012 Oct;228(2):230-40. doi: 10.1002/path.4011. Epub 2012 Jul 26.
508 A secreted form of P-cadherin is expressed in malignant melanoma.Exp Cell Res. 2005 May 1;305(2):418-26. doi: 10.1016/j.yexcr.2005.01.024.
509 The IKK-dependent non-canonical pathway of NF-B activation is constitutively active and modulates progression-related functions in a subset of human melanomas.Arch Dermatol Res. 2016 Dec;308(10):733-742. doi: 10.1007/s00403-016-1696-x. Epub 2016 Oct 15.
510 TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma.Sci Transl Med. 2013 Jul 31;5(196):196ra98. doi: 10.1126/scitranslmed.3005753.
511 CD114 Expression Mediates Melanoma Tumor Cell Growth and Treatment Resistance.Anticancer Res. 2015 Jul;35(7):3787-92.
512 Phosphoproteomics of MAPK inhibition in BRAF-mutated cells and a role for the lethal synergism of dual BRAF and CK2 inhibition.Mol Cancer Ther. 2014 Jul;13(7):1894-906. doi: 10.1158/1535-7163.MCT-13-0938. Epub 2014 May 13.
513 Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.Oncogene. 2003 May 15;22(19):2869-81. doi: 10.1038/sj.onc.1206427.
514 Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin.Tumour Biol. 2014 Aug;35(8):8225-33. doi: 10.1007/s13277-014-2098-3. Epub 2014 May 22.
515 Role of EIF5A2, a downstream target of Akt, in promoting melanoma cell invasion.Br J Cancer. 2014 Jan 21;110(2):399-408. doi: 10.1038/bjc.2013.688. Epub 2013 Oct 31.
516 Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.Melanoma Res. 2013 Apr;23(2):85-95. doi: 10.1097/CMR.0b013e32835e58f3.
517 LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.J Cell Biol. 2014 Oct 27;207(2):299-315. doi: 10.1083/jcb.201404067.
518 Synchronous occurrence of medullary and papillary carcinoma of the thyroid in a patient with cutaneous melanoma: determination of BRAFV600E in peripheral blood and tissues. Report of a case and review of the literature.Endocr Pathol. 2014 Sep;25(3):324-31. doi: 10.1007/s12022-014-9303-1.
519 Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton.Carcinogenesis. 2002 Oct;23(10):1593-601. doi: 10.1093/carcin/23.10.1593.
520 Selective expression of inhibitory Fcgamma receptor by metastatic melanoma impairs tumor susceptibility to IgG-dependent cellular response.Int J Cancer. 2008 Dec 15;123(12):2832-9. doi: 10.1002/ijc.23870.
521 Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention.J Hepatol. 2009 Jan;50(1):118-27. doi: 10.1016/j.jhep.2008.08.015. Epub 2008 Oct 12.
522 Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway.Oncotarget. 2015 Jun 10;6(16):14290-9. doi: 10.18632/oncotarget.3742.
523 A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors.Epigenetics. 2014 Aug;9(8):1163-71. doi: 10.4161/epi.29628. Epub 2014 Jul 8.
524 Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function.Cell Cycle. 2014;13(17):2790-7. doi: 10.4161/15384101.2015.945879.
525 The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans.Front Neuroendocrinol. 2003 Dec;24(4):279-95. doi: 10.1016/j.yfrne.2003.10.003.
526 Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement in clinical cancer specimens.J Mol Diagn. 2014 Jan;16(1):56-67. doi: 10.1016/j.jmoldx.2013.08.004. Epub 2013 Nov 2.
527 Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to PK oncolytic activity in melanoma.Gene Ther. 2014 Apr;21(4):371-8. doi: 10.1038/gt.2014.6. Epub 2014 Feb 20.
528 Downregulation of hepatoma-derived growth factor contributes to retarded lung metastasis via inhibition of epithelial-mesenchymal transition by systemic POMC gene delivery in melanoma.Mol Cancer Ther. 2013 Jun;12(6):1016-25. doi: 10.1158/1535-7163.MCT-12-0832. Epub 2013 Mar 6.
529 Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma.J Invest Dermatol. 2015 Sep;135(9):2283-2291. doi: 10.1038/jid.2015.160. Epub 2015 Apr 24.
530 Epigenetic silencing of novel tumor suppressors in malignant melanoma. Cancer Res. 2006 Dec 1;66(23):11187-93. doi: 10.1158/0008-5472.CAN-06-1274.
531 Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer.Gynecol Oncol. 2006 Oct;103(1):253-60. doi: 10.1016/j.ygyno.2006.03.006. Epub 2006 May 2.
532 Anti-IL-23 monoclonal antibody synergizes in combination with targeted therapies or IL-2 to suppress tumor growth and metastases.Cancer Res. 2011 Mar 15;71(6):2077-86. doi: 10.1158/0008-5472.CAN-10-3994. Epub 2011 Jan 31.
533 PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma.Nat Commun. 2013;4:1508. doi: 10.1038/ncomms2489.
534 Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells.BMC Cancer. 2010 Apr 14;10:142. doi: 10.1186/1471-2407-10-142.
535 Retrotransposon hypomethylation in melanoma and expression of a placenta-specific gene.PLoS One. 2014 Apr 23;9(4):e95840. doi: 10.1371/journal.pone.0095840. eCollection 2014.
536 Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.Cancer Cell. 2018 Feb 12;33(2):322-336.e8. doi: 10.1016/j.ccell.2018.01.002.
537 The kisspeptin (KiSS-1)/GPR54 system in cancer biology.Cancer Treat Rev. 2008 Dec;34(8):682-92. doi: 10.1016/j.ctrv.2008.05.007. Epub 2008 Jun 25.
538 LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression.PLoS One. 2015 Jun 10;10(6):e0129219. doi: 10.1371/journal.pone.0129219. eCollection 2015.
539 High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma.Oncotarget. 2015 Sep 22;6(28):25484-98. doi: 10.18632/oncotarget.4688.
540 Investigation of prognostic indicators for human uveal melanoma as biomarkers of canine uveal melanoma metastasis.J Small Anim Pract. 2013 Nov;54(11):584-93. doi: 10.1111/jsap.12141.
541 Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):E3640-9. doi: 10.1073/pnas.1314435110. Epub 2013 Sep 3.
542 Matrix metalloproteinase-12 expression is increased in cutaneous melanoma and associated with tumor aggressiveness.Tumour Biol. 2015 Nov;36(11):8593-600. doi: 10.1007/s13277-015-3622-9. Epub 2015 Jun 4.
543 Enhancement of survivin-specific anti-tumor immunity by adenovirus prime protein-boost immunity strategy with DDA/MPL adjuvant in a murine melanoma model.Int Immunopharmacol. 2013 Sep;17(1):9-17. doi: 10.1016/j.intimp.2013.04.015. Epub 2013 Apr 25.
544 Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R.Melanoma Res. 2011 Aug;21(4):274-84. doi: 10.1097/CMR.0b013e328343a1d6.
545 Polymorphisms in base excision DNA repair genes and association with melanoma risk in a pilot study on Central-South Italian population.Clin Chim Acta. 2012 Oct 9;413(19-20):1519-24. doi: 10.1016/j.cca.2012.06.013. Epub 2012 Jun 9.
546 N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis.EMBO J. 2001 Mar 15;20(6):1383-93. doi: 10.1093/emboj/20.6.1383.
547 Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms.Int J Oncol. 2013 Jul;43(1):297-306. doi: 10.3892/ijo.2013.1948. Epub 2013 May 20.
548 The embryonic morphogen, Nodal, is associated with channel-like structures in human malignant melanoma xenografts.J Cutan Pathol. 2010 Apr;37 Suppl 1(Suppl 1):19-25. doi: 10.1111/j.1600-0560.2010.01503.x.
549 Involvement of Nurr-1/Nur77 in corticotropin-releasing factor/urocortin1-induced tyrosinase-related protein 1 gene transcription in human melanoma HMV-II cells.Mol Cell Endocrinol. 2013 May 6;370(1-2):42-51. doi: 10.1016/j.mce.2013.01.022. Epub 2013 Feb 14.
550 Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk.Cancer Epidemiol Biomarkers Prev. 2014 Jun;23(6):1121-4. doi: 10.1158/1055-9965.EPI-13-0627. Epub 2014 Mar 18.
551 miR?6 functions as a tumor suppressor gene by targeting NUAK1 in pancreatic cancer.Int J Mol Med. 2014 Dec;34(6):1599-605. doi: 10.3892/ijmm.2014.1940. Epub 2014 Sep 19.
552 STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.J Cell Biol. 2014 Nov 24;207(4):535-48. doi: 10.1083/jcb.201407082. Epub 2014 Nov 17.
553 Proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors in the treatment of hypercholesterolemia and other pathologies.Curr Pharm Des. 2013;19(17):3161-72. doi: 10.2174/13816128113199990313.
554 Associations between smoking behavior-related alleles and the risk of melanoma.Oncotarget. 2016 Jul 26;7(30):47366-47375. doi: 10.18632/oncotarget.10144.
555 Characterization of phosphodiesterase 2A in human malignant melanoma PMP cells.Oncol Rep. 2013 Apr;29(4):1275-84. doi: 10.3892/or.2013.2260. Epub 2013 Jan 31.
556 Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes.Int J Cancer. 1994 Oct 1;59(1):78-82. doi: 10.1002/ijc.2910590116.
557 Gene expression analysis to identify mRNA markers of cardiac myxoma.J Mol Cell Cardiol. 2004 Sep;37(3):717-33. doi: 10.1016/j.yjmcc.2004.06.006.
558 Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor.Cancer Res. 2004 Jan 1;64(1):13-8. doi: 10.1158/0008-5472.can-03-2658.
559 Loss of MiR-664 Expression Enhances Cutaneous Malignant Melanoma Proliferation by Upregulating PLP2.Medicine (Baltimore). 2015 Aug;94(33):e1327. doi: 10.1097/MD.0000000000001327.
560 Genetic variants in DNA repair genes and the risk of cutaneous malignant melanoma in melanoma-prone families with/without CDKN2A mutations.Int J Cancer. 2012 May 1;130(9):2062-6. doi: 10.1002/ijc.26231. Epub 2011 Aug 9.
561 PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.Mol Cancer Res. 2019 Feb;17(2):583-593. doi: 10.1158/1541-7786.MCR-18-0777. Epub 2018 Oct 24.
562 Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients.Oncogene. 2004 May 13;23(22):4014-22. doi: 10.1038/sj.onc.1207505.
563 Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells.Exp Dermatol. 2010 Nov;19(11):1023-5. doi: 10.1111/j.1600-0625.2010.01126.x. Epub 2010 Aug 31.
564 Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma.Mol Cancer Res. 2016 Sep;14(9):767-75. doi: 10.1158/1541-7786.MCR-16-0099. Epub 2016 Jun 13.
565 Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model.PLoS One. 2012;7(3):e33633. doi: 10.1371/journal.pone.0033633. Epub 2012 Mar 20.
566 New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations.Biochim Biophys Acta. 2016 Nov;1863(11):2710-2718. doi: 10.1016/j.bbamcr.2016.08.007. Epub 2016 Aug 16.
567 Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma.Br J Cancer. 2014 Jul 29;111(3):477-85. doi: 10.1038/bjc.2014.342. Epub 2014 Jul 10.
568 Uveal melanoma expresses NK-1 receptors and cyclosporin A induces apoptosis in human melanoma cell lines overexpressing the NK-1 receptor.Peptides. 2014 May;55:1-12. doi: 10.1016/j.peptides.2014.01.030. Epub 2014 Feb 15.
569 Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.EMBO Mol Med. 2013 Nov;5(11):1720-39. doi: 10.1002/emmm.201302524. Epub 2013 Oct 11.
570 Thrombomodulin modulates cell migration in human melanoma cell lines.Melanoma Res. 2014 Feb;24(1):11-9. doi: 10.1097/CMR.0000000000000035.
571 Constitutive RAC activation is not sufficient to initiate melanocyte neoplasia but accelerates malignant progression.J Invest Dermatol. 2013 Jun;133(6):1572-81. doi: 10.1038/jid.2013.23. Epub 2013 Jan 21.
572 TWEAK activation of the non-canonical NF-B signaling pathway differentially regulates melanoma and prostate cancer cell invasion.Oncotarget. 2016 Dec 6;7(49):81474-81492. doi: 10.18632/oncotarget.13034.
573 Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression.Cancer Res. 2014 Jan 1;74(1):130-40. doi: 10.1158/0008-5472.CAN-13-1672.
574 Induction of potent anti-tumor immunity by direct injection of Ad-LIGHT at the site of tumor inoculation.Cytotherapy. 2007;9(4):386-96. doi: 10.1080/14653240701326749.
575 C-terminal tensin-like protein is a novel prognostic marker for primary melanoma patients.PLoS One. 2013 Nov 7;8(11):e80492. doi: 10.1371/journal.pone.0080492. eCollection 2013.
576 Camptothecin induces p53-dependent and -independent apoptogenic signaling in melanoma cells.Apoptosis. 2011 Nov;16(11):1165-76. doi: 10.1007/s10495-011-0635-8.
577 Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles.Nucleic Acids Res. 2015 Apr 20;43(7):e44. doi: 10.1093/nar/gku1393. Epub 2015 Jan 8.
578 Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.Oncotarget. 2015 Jun 30;6(18):16488-506. doi: 10.18632/oncotarget.4108.
579 Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.Oncotarget. 2015 Nov 3;6(34):36338-53. doi: 10.18632/oncotarget.5537.
580 Disorders of nucleotide excision repair.Handb Clin Neurol. 2013;113:1637-50. doi: 10.1016/B978-0-444-59565-2.00032-0.
581 Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.PLoS One. 2014 Jul 24;9(7):e102983. doi: 10.1371/journal.pone.0102983. eCollection 2014.
582 Overcoming Resistance to Targeted Therapies in Cancer.Semin Oncol. 2015 Dec;42(6):896-908. doi: 10.1053/j.seminoncol.2015.09.028. Epub 2015 Sep 25.
583 Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes.PLoS Genet. 2016 Jun 15;12(6):e1006081. doi: 10.1371/journal.pgen.1006081. eCollection 2016 Jun.
584 Ousting RAGE in melanoma: A viable therapeutic target?.Semin Cancer Biol. 2018 Apr;49:20-28. doi: 10.1016/j.semcancer.2017.10.008. Epub 2017 Oct 24.
585 Novel therapeutic compound acridine-retrotuftsin action on biological forms of melanoma and neuroblastoma.J Cancer Res Clin Oncol. 2019 Jan;145(1):165-179. doi: 10.1007/s00432-018-2776-4. Epub 2018 Oct 26.
586 Aryl Hydrocarbon Receptor Modulates Carcinogenesis and Maintenance of Skin Cancers.Front Med (Lausanne). 2019 Sep 4;6:194. doi: 10.3389/fmed.2019.00194. eCollection 2019.
587 SHARPIN Promotes Melanoma Progression viaRap1 Signaling Pathway.J Invest Dermatol. 2020 Feb;140(2):395-403.e6. doi: 10.1016/j.jid.2019.07.696. Epub 2019 Aug 8.
588 AKT1(E17K) Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.Mol Cancer Res. 2019 Sep;17(9):1787-1800. doi: 10.1158/1541-7786.MCR-18-1372. Epub 2019 May 28.
589 Immunohistochemical CD271 expression correlates with melanoma progress in a case-control study.Pathology. 2018 Jun;50(4):402-410. doi: 10.1016/j.pathol.2017.12.340. Epub 2018 Apr 17.
590 Current Treatment Options for Breast Cancer Brain Metastases.Curr Treat Options Oncol. 2019 Feb 15;20(3):19. doi: 10.1007/s11864-019-0618-5.
591 Molecular identification, localization and function of platelet-type 12-lipoxygenase in human melanoma progression, under experimental and clinical conditions.Melanoma Res. 2004 Aug;14(4):245-50. doi: 10.1097/01.cmr.0000138479.00897.d8.
592 Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma.Melanoma Res. 2004 Apr;14(2):135-40. doi: 10.1097/00008390-200404000-00010.
593 Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.Oncotarget. 2014 May 30;5(10):3273-86. doi: 10.18632/oncotarget.1926.
594 In vivo modulation of angiogenesis by beta 2 glycoprotein I.J Autoimmun. 2010 Nov;35(3):232-40. doi: 10.1016/j.jaut.2010.06.013. Epub 2010 Jul 24.
595 Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors.Am J Clin Pathol. 2019 Sep 9;152(4):446-457. doi: 10.1093/ajcp/aqz066.
596 Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth.Cancers (Basel). 2019 Nov 22;11(12):1847. doi: 10.3390/cancers11121847.
597 Screening of germline mutations in the CDK4, CDKN2C and TP53 genes in familial melanoma: a clinic-based population study.Int J Cancer. 1998 Sep 25;78(1):13-5. doi: 10.1002/(sici)1097-0215(19980925)78:1<13::aid-ijc3>3.0.co;2-#.
598 MiR-154 inhibits cells proliferation and metastasis in melanoma by targeting AURKA and serves as a novel prognostic indicator.Eur Rev Med Pharmacol Sci. 2019 May;23(10):4275-4284. doi: 10.26355/eurrev_201905_17932.
599 Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.J Transl Med. 2015 Jan 27;13:26. doi: 10.1186/s12967-015-0385-4.
600 AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma.Oncogene. 2018 Jun;37(24):3275-3289. doi: 10.1038/s41388-018-0205-4. Epub 2018 Mar 19.
601 Analysis of the Tumor Reactivity of Tumor-Infiltrating Lymphocytes in a Metastatic Melanoma Lesion that Lost Major Histocompatibility Complex Class I Expression after Anti-PD-1 Therapy.J Invest Dermatol. 2019 Jul;139(7):1490-1496. doi: 10.1016/j.jid.2019.01.007. Epub 2019 Jan 23.
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611 Carbonic anhydrase II is a tumor vessel endothelium-associated antigen targeted by dendritic cell therapy.Clin Cancer Res. 2005 Nov 15;11(22):8201-7. doi: 10.1158/1078-0432.CCR-05-0816.
612 Correction: CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma.Oncotarget. 2019 Feb 12;10(13):1344. doi: 10.18632/oncotarget.26685. eCollection 2019 Feb 12.
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615 Cisplatin-induced apoptosis in melanoma cells: role of caspase-3 and caspase-7 in Apaf-1 proteolytic cleavage and in execution of the degradative phases.Ann N Y Acad Sci. 2003 Dec;1010:200-4. doi: 10.1196/annals.1299.034.
616 CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus.Oncogene. 2005 Aug 25;24(36):5543-51. doi: 10.1038/sj.onc.1208735.
617 Gastrin exerts pleiotropic effects on human melanoma cell biology.Neoplasia. 2005 Oct;7(10):930-43. doi: 10.1593/neo.05379.
618 Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9271-E9279. doi: 10.1073/pnas.1703921114. Epub 2017 Oct 16.
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636 Immunization With the CSF-470 Vaccine Plus BCG and rhGM-CSF Induced in a Cutaneous Melanoma Patient a TCR Repertoire Found at Vaccination Site and Tumor Infiltrating Lymphocytes That Persisted in Blood.Front Immunol. 2019 Sep 18;10:2213. doi: 10.3389/fimmu.2019.02213. eCollection 2019.
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640 The programmed cell death protein-1/programmed cell death ligand 1 expression, CD3+ T cell infiltration, NY-ESO-1 expression, and microsatellite instability phenotype in primary cutaneous melanoma and mucosal melanoma and their clinical significance and prognostic value: a study of 89 consecutive cases.Melanoma Res. 2020 Feb;30(1):85-101. doi: 10.1097/CMR.0000000000000620.
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642 High-resolution interrogation of functional elements in the noncoding genome.Science. 2016 Sep 30;353(6307):1545-1549. doi: 10.1126/science.aaf7613.
643 Targeting tumor-resident mast cells for effective anti-melanoma immune responses.JCI Insight. 2019 Oct 3;4(19):e125057. doi: 10.1172/jci.insight.125057.
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646 CXCR4 inhibition modulates the tumor microenvironment and retards the growth of B16-OVA melanoma and Renca tumors.Melanoma Res. 2020 Feb;30(1):14-25. doi: 10.1097/CMR.0000000000000639.
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648 Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite.Biomolecules. 2019 Aug 24;9(9):409. doi: 10.3390/biom9090409.
649 Downregulation of discoidin domain receptor 2 in A375 human melanoma cells reduces its experimental liver metastasis ability.Oncol Rep. 2011 Oct;26(4):971-8. doi: 10.3892/or.2011.1356. Epub 2011 Jun 23.
650 Diacylglycerol kinase -selective inhibitors induce apoptosis and reduce viability of melanoma and several other cancer cell lines.J Cell Biochem. 2019 Jun;120(6):10043-10056. doi: 10.1002/jcb.28288. Epub 2018 Dec 9.
651 DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis.Int J Cancer. 2005 Jun 10;115(2):224-30. doi: 10.1002/ijc.20885.
652 Expression of Dickkopf genes is strongly reduced in malignant melanoma.Oncogene. 2006 Aug 17;25(36):5027-36. doi: 10.1038/sj.onc.1209508. Epub 2006 Mar 27.
653 Different pattern of T cell receptor delta gene rearrangement in tumour-infiltrating lymphocytes and peripheral blood in patients with solid tumours.Cancer Immunol Immunother. 1994 Oct;39(4):275-8. doi: 10.1007/BF01525992.
654 Knockdown of Delta-like 3 restricts lipopolysaccharide-induced inflammation, migration and invasion of A2058 melanoma cells via blocking Twist1-mediated epithelial-mesenchymal transition.Life Sci. 2019 Jun 1;226:149-155. doi: 10.1016/j.lfs.2019.04.024. Epub 2019 Apr 11.
655 Triptolide modulates tumour-colonisation and anti-tumour effect of attenuated Salmonella encoding DNase I.Appl Microbiol Biotechnol. 2019 Jan;103(2):929-939. doi: 10.1007/s00253-018-9481-8. Epub 2018 Nov 17.
656 Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers.Pathol Oncol Res. 2020 Jul;26(3):1539-1547. doi: 10.1007/s12253-019-00734-w. Epub 2019 Sep 2.
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658 E2F1 germline copy number variations and melanoma susceptibility.J Transl Med. 2019 May 29;17(1):181. doi: 10.1186/s12967-019-1933-0.
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665 Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma.Bioorg Chem. 2019 Feb;82:290-305. doi: 10.1016/j.bioorg.2018.10.044. Epub 2018 Oct 23.
666 Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R.PLoS One. 2014 Jan 29;9(1):e84417. doi: 10.1371/journal.pone.0084417. eCollection 2014.
667 Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1).Cancer Immunol Immunother. 2019 Aug;68(8):1245-1261. doi: 10.1007/s00262-019-02358-0. Epub 2019 Jun 20.
668 Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma.Nat Commun. 2017 Feb 15;8:14449. doi: 10.1038/ncomms14449.
669 Assembly and regulation of prothrombinase complex on B16F10 melanoma cells.Thromb Res. 2005;115(1-2):123-9. doi: 10.1016/j.thromres.2004.08.001.
670 miR-20b regulates expression of proteinase-activated receptor-1 (PAR-1) thrombin receptor in melanoma cells.Pigment Cell Melanoma Res. 2014 May;27(3):431-41. doi: 10.1111/pcmr.12217. Epub 2014 Feb 6.
671 Dabrafenib and Trametinibprolong coagulation through the inhibition of tissue factor in BRAF(v600e) mutated melanoma cells in vitro.Cancer Cell Int. 2019 Aug 28;19:223. doi: 10.1186/s12935-019-0938-3. eCollection 2019.
672 Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.Invest Ophthalmol Vis Sci. 2012 Jul 9;53(8):4634-43. doi: 10.1167/iovs.11-9019.
673 Defective FasL expression is associated with increased resistance to melanoma liver metastases and enhanced natural killer cell activity.Melanoma Res. 2019 Aug;29(4):401-412. doi: 10.1097/CMR.0000000000000614.
674 Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products.J Biol Chem. 2011 Aug 12;286(32):28181-91. doi: 10.1074/jbc.M111.234419. Epub 2011 Jun 16.
675 VIT1/FBXO11 knockdown induces morphological alterations and apoptosis in B10BR mouse melanocytes.Int J Mol Med. 2009 May;23(5):673-8. doi: 10.3892/ijmm_00000179.
676 Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity. J Clin Invest. 2012 Oct;122(10):3769-80. doi: 10.1172/JCI64837. Epub 2012 Sep 24.
677 Sasanquasaponin from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells.Phytomedicine. 2019 May;58:152769. doi: 10.1016/j.phymed.2018.11.029. Epub 2018 Nov 20.
678 Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition.J Invest Dermatol. 2011 Oct;131(10):2087-95. doi: 10.1038/jid.2011.177. Epub 2011 Jul 14.
679 The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A.J Immunol. 2012 Aug 15;189(4):1946-54. doi: 10.4049/jimmunol.1201064. Epub 2012 Jul 9.
680 Epigenetic activation of AP1 promotes squamous cell carcinoma metastasis.Sci Signal. 2013 Apr 30;6(273):ra28.1-13, S0-15. doi: 10.1126/scisignal.2003884.
681 The FOXC2 Transcription Factor Promotes Melanoma Outgrowth and Regulates Expression of Genes Associated With Drug Resistance and Interferon Responsiveness.Cancer Genomics Proteomics. 2019 Nov-Dec;16(6):491-503. doi: 10.21873/cgp.20152.
682 Clinical and Therapeutic Implications of Follistatin in Solid Tumours.Cancer Genomics Proteomics. 2016 11-12;13(6):425-435. doi: 10.21873/cgp.20005.
683 Identification of robust reference genes for studies of gene expression in FFPE melanoma samples and melanoma cell lines.Melanoma Res. 2020 Feb;30(1):26-38. doi: 10.1097/CMR.0000000000000644.
684 Increased expression of long noncoding RNA GAS6-AS2 promotes proliferation and inhibits apoptosis of melanoma cells via upregulating GAS6 expression.IUBMB Life. 2019 Oct;71(10):1503-1514. doi: 10.1002/iub.2071. Epub 2019 Jun 4.
685 Histamine receptor 2-mediated growth-differentiation factor-15 expression is involved in histamine-induced melanogenesis.Int J Biochem Cell Biol. 2012 Dec;44(12):2124-8. doi: 10.1016/j.biocel.2012.08.020. Epub 2012 Sep 2.
686 Redox modulation of NF-kappaB nuclear translocation and DNA binding in metastatic melanoma. The role of endogenous and gamma-glutamyl transferase-dependent oxidative stress.Tumori. 2003 Jul-Aug;89(4):426-33. doi: 10.1177/030089160308900416.
687 Exploring Differential Connexin Expression across Melanocytic Tumor Progression Involving the Tumor Microenvironment.Cancers (Basel). 2019 Feb 1;11(2):165. doi: 10.3390/cancers11020165.
688 Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.Oncogene. 2017 Mar 30;36(13):1849-1861. doi: 10.1038/onc.2016.348. Epub 2016 Oct 17.
689 Transcriptional repression of the tyrosinase-related protein 2 gene by transforming growth factor- and the Kruppel-like transcription factor GLI2.J Dermatol Sci. 2019 Jun;94(3):321-329. doi: 10.1016/j.jdermsci.2019.04.001. Epub 2019 Apr 6.
690 miR-137 inhibits melanoma cell proliferation through downregulation of GLO1.Sci China Life Sci. 2018 May;61(5):541-549. doi: 10.1007/s11427-017-9138-9. Epub 2018 Jan 2.
691 GPR56 and its related diseases.Prog Mol Biol Transl Sci. 2009;89:1-13. doi: 10.1016/S1877-1173(09)89001-7. Epub 2009 Oct 7.
692 Genetic and Functional Analysis of GRIN2A in Tumor Samples.Methods Mol Biol. 2017;1677:93-116. doi: 10.1007/978-1-4939-7321-7_3.
693 Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling.Pigment Cell Melanoma Res. 2018 Jan;31(1):115-119. doi: 10.1111/pcmr.12610. Epub 2017 Oct 23.
694 MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma.Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15840-5. doi: 10.1073/pnas.1019312108. Epub 2011 Sep 6.
695 Effect of hyperthermia on the viability and the fibrinolytic potential of human cancer cell lines.Clin Chim Acta. 2000 Jun;296(1-2):17-33. doi: 10.1016/s0009-8981(00)00198-4.
696 HAX-1, identified by differential display reverse transcription polymerase chain reaction, is overexpressed in lesional psoriasis.J Invest Dermatol. 2003 Jun;120(6):1045-51. doi: 10.1046/j.1523-1747.2003.12247.x.
697 Evaluation of [(11)C]KB631 as a PET tracer for in vivo visualisation of HDAC6 in B16.F10 melanoma.Nucl Med Biol. 2019 Jul-Aug;74-75:1-11. doi: 10.1016/j.nucmedbio.2019.05.004. Epub 2019 May 29.
698 MicroRNA-329 upregulation impairs the HMGB2/-catenin pathway and regulates cell biological behaviors in melanoma.J Cell Physiol. 2019 Dec;234(12):23518-23527. doi: 10.1002/jcp.28920. Epub 2019 Jun 20.
699 Altered expressions of HOX genes in human cutaneous malignant melanoma.Int J Cancer. 2005 Apr 10;114(3):436-41. doi: 10.1002/ijc.20706.
700 Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid.J Clin Invest. 2009 Apr;119(4):954-63. doi: 10.1172/JCI34015. Epub 2009 Mar 9.
701 Histamine elevates the expression of Ets-1, a protooncogen in human melanoma cell lines through H2 receptor.FEBS Lett. 2005 Apr 25;579(11):2475-9. doi: 10.1016/j.febslet.2005.03.053.
702 Inhibitors of HSP90 in melanoma.Apoptosis. 2020 Feb;25(1-2):12-28. doi: 10.1007/s10495-019-01577-1.
703 High-resolution population structure and runs of homozygosity reveal the genetic architecture of complex traits in the Lipizzan horse.BMC Genomics. 2019 Mar 5;20(1):174. doi: 10.1186/s12864-019-5564-x.
704 Antitumor agent 25-epi Ritterostatin GN1N induces endoplasmic reticulum stress and autophagy mediated cell death in melanoma cells.Int J Oncol. 2017 May;50(5):1482-1490. doi: 10.3892/ijo.2017.3944. Epub 2017 Apr 3.
705 Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells.Cancer Res. 2010 Dec 1;70(23):9581-90. doi: 10.1158/0008-5472.CAN-10-1379. Epub 2010 Nov 23.
706 Regorafenib Promotes Antitumor Immunity via Inhibiting PD-L1 and IDO1 Expression in Melanoma.Clin Cancer Res. 2019 Jul 15;25(14):4530-4541. doi: 10.1158/1078-0432.CCR-18-2840. Epub 2019 Apr 2.
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708 Phase II multicenter study of neoadjuvant biochemotherapy for patients with stage III malignant melanoma.J Clin Oncol. 2006 Jul 1;24(19):3157-63. doi: 10.1200/JCO.2005.04.5344.
709 Interferon- sensitizes human malignant melanoma cells to temozolomide-induced apoptosis and autophagy.Int J Oncol. 2019 May;54(5):1864-1874. doi: 10.3892/ijo.2019.4743. Epub 2019 Mar 7.
710 Regulatory B1a Cells Suppress Melanoma Tumor Immunity via IL-10 Production and Inhibiting T Helper Type 1 Cytokine Production in Tumor-Infiltrating CD8(+) T Cells.J Invest Dermatol. 2019 Jul;139(7):1535-1544.e1. doi: 10.1016/j.jid.2019.02.016. Epub 2019 Mar 2.
711 Restoration of the expression of transports associated with antigen processing in human malignant melanoma increases tumor-specific immunity.J Invest Dermatol. 2008 Aug;128(8):1991-6. doi: 10.1038/jid.2008.10. Epub 2008 Apr 3.
712 Adipocytes: A Novel Target for IL-15/IL-15R Cancer Gene Therapy.Mol Ther. 2019 May 8;27(5):922-932. doi: 10.1016/j.ymthe.2019.02.011. Epub 2019 Feb 16.
713 IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner.PLoS One. 2013 Oct 14;8(10):e76159. doi: 10.1371/journal.pone.0076159. eCollection 2013.
714 IL-19 induced Th2 cytokines and was up-regulated in asthma patients.J Immunol. 2004 Dec 1;173(11):6712-8. doi: 10.4049/jimmunol.173.11.6712.
715 Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma.Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3100-3105. doi: 10.1073/pnas.1815087116. Epub 2019 Feb 4.
716 MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5687-5692. doi: 10.1073/pnas.1819869116. Epub 2019 Mar 6.
717 IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo.Cancer Immunol Immunother. 2010 Jun;59(6):805-17. doi: 10.1007/s00262-009-0802-8. Epub 2009 Dec 13.
718 A human recombinant IL-7/HGF hybrid cytokine enhances antitumor immunity in mice.Am J Cancer Res. 2017 Aug 1;7(8):1714-1723. eCollection 2017.
719 Investigation of IGF2/ApaI and H19/RsaI polymorphisms in patients with cutaneous melanoma.Growth Horm IGF Res. 2010 Aug;20(4):295-7. doi: 10.1016/j.ghir.2010.03.006. Epub 2010 May 18.
720 Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization.Gene. 2004 Dec 8;343(1):191-201. doi: 10.1016/j.gene.2004.09.002.
721 IFN regulatory factor-8 expression in macrophages governs an antimetastatic program.JCI Insight. 2019 Feb 7;4(3):e124267. doi: 10.1172/jci.insight.124267.
722 Insights into Fibroblast Plasticity: Cellular Communication Network 2 Is Required for Activation of Cancer-Associated Fibroblasts in a Murine Model of Melanoma.Am J Pathol. 2020 Jan;190(1):206-221. doi: 10.1016/j.ajpath.2019.09.006. Epub 2019 Oct 11.
723 PRL-3/PTP4A3 phosphatase regulates integrin 1 in adhesion structures during migration of human ocular melanoma cells.Exp Cell Res. 2017 Apr 15;353(2):88-99. doi: 10.1016/j.yexcr.2017.03.012. Epub 2017 Mar 8.
724 Blockade of integrin 3 signals to reverse the stem-like phenotype and drug resistance in melanoma.Cancer Chemother Pharmacol. 2019 Apr;83(4):615-624. doi: 10.1007/s00280-018-3760-z. Epub 2019 Jan 9.
725 Targeted Radionuclide Therapy Decreases Melanoma Lung Invasion by Modifying Epithelial-Mesenchymal Transition-Like Mechanisms.Transl Oncol. 2019 Nov;12(11):1442-1452. doi: 10.1016/j.tranon.2019.07.015. Epub 2019 Aug 14.
726 Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.Pigment Cell Melanoma Res. 2019 Jul;32(4):528-539. doi: 10.1111/pcmr.12764. Epub 2019 Feb 3.
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728 Targeting the H3K4 Demethylase KDM5B Reprograms the Metabolome and Phenotype of Melanoma Cells.J Invest Dermatol. 2019 Dec;139(12):2506-2516.e10. doi: 10.1016/j.jid.2019.06.124. Epub 2019 Jun 21.
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775 Effective Combined Photodynamic Therapy with Lipid Platinum Chloride Nanoparticles Therapies of Oral Squamous Carcinoma Tumor Inhibition.J Clin Med. 2019 Dec 2;8(12):2112. doi: 10.3390/jcm8122112.
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783 Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.Oncotarget. 2017 Mar 14;8(11):17586-17592. doi: 10.18632/oncotarget.15230.
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790 Analyses of molecular and histopathologic features and expression of PRAME by immunohistochemistry in mucosal melanomas.Mod Pathol. 2019 Dec;32(12):1727-1733. doi: 10.1038/s41379-019-0335-4. Epub 2019 Aug 2.
791 Protein kinase C- is upregulated by IMP1 in melanoma and is linked to poor survival.Melanoma Res. 2019 Oct;29(5):539-543. doi: 10.1097/CMR.0000000000000558.
792 Recent insights into apoptosis and toxic autophagy: The roles of MDA-7/IL-24, a multidimensional anti-cancer therapeutic.Semin Cancer Biol. 2020 Nov;66:140-154. doi: 10.1016/j.semcancer.2019.07.013. Epub 2019 Jul 26.
793 Survival and prognosis of individuals receiving programmed cell death 1 inhibitor with and without immunologic cutaneous adverse events.J Am Acad Dermatol. 2020 Feb;82(2):311-316. doi: 10.1016/j.jaad.2019.06.035. Epub 2019 Jun 21.
794 Variable expression of protein kinase C epsilon in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis.Mol Cancer Ther. 2005 Apr;4(4):668-76. doi: 10.1158/1535-7163.MCT-04-0332.
795 Protein kinase C isoforms in normal and transformed cells of the melanocytic lineage.Melanoma Res. 2002 Jun;12(3):201-9. doi: 10.1097/00008390-200206000-00003.
796 High FcR Expression on Intratumoral Macrophages Enhances Tumor-Targeting Antibody Therapy.J Immunol. 2018 Dec 15;201(12):3741-3749. doi: 10.4049/jimmunol.1800700. Epub 2018 Nov 5.
797 Immunohistochemical detectability of cyclooxygenase-2 expression in cells of human melanocytic skin lesions: A methodological review.J Cutan Pathol. 2020 Apr;47(4):363-380. doi: 10.1111/cup.13606. Epub 2019 Dec 1.
798 The phosphatase SRC homology region 2 domain-containing phosphatase-1 is an intrinsic central regulator of dendritic cell function.J Immunol. 2011 Apr 1;186(7):3934-45. doi: 10.4049/jimmunol.1001675. Epub 2011 Feb 25.
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801 Long noncoding RNA ZFAS1 promotes tumorigenesis through regulation of miR-150-5p/RAB9A in melanoma.Melanoma Res. 2019 Dec;29(6):569-581. doi: 10.1097/CMR.0000000000000595.
802 A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression.Cancer Lett. 2019 Aug 10;457:151-167. doi: 10.1016/j.canlet.2019.05.009. Epub 2019 May 17.
803 MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer.Curr Top Microbiol Immunol. 2017;407:117-151. doi: 10.1007/82_2017_4.
804 Pancreatitis associated protein I (PAP-I) alters adhesion and motility of human melanocytes and melanoma cells.J Invest Dermatol. 2001 Mar;116(3):426-33. doi: 10.1046/j.1523-1747.2001.01278.x.
805 The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion.Curr Cancer Drug Targets. 2008 Aug;8(5):404-13. doi: 10.2174/156800908785133141.
806 Photoreceptor proteins as cancer-retina antigens.Int J Cancer. 2007 Mar 15;120(6):1268-76. doi: 10.1002/ijc.22458.
807 Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors.Oncogene. 2003 Feb 27;22(8):1124-34. doi: 10.1038/sj.onc.1206181.
808 Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.Cancer Cell. 2003 Jul;4(1):19-29. doi: 10.1016/s1535-6108(03)00164-8.
809 CX-F9, a novel RSK2 inhibitor, suppresses cutaneous melanoma cells proliferation and metastasis through regulating autophagy.Biochem Pharmacol. 2019 Oct;168:14-25. doi: 10.1016/j.bcp.2019.06.014. Epub 2019 Jun 14.
810 Rsf? regulates malignant melanoma cell viability and chemoresistance via NFB/Bcl? signaling.Mol Med Rep. 2019 Oct;20(4):3487-3498. doi: 10.3892/mmr.2019.10610. Epub 2019 Aug 23.
811 Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies.J Immunother Cancer. 2019 Dec 5;7(1):343. doi: 10.1186/s40425-019-0828-1.
812 The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes.PLoS One. 2011;6(7):e22560. doi: 10.1371/journal.pone.0022560. Epub 2011 Jul 28.
813 Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.Neoplasia. 2014 Jun;16(6):529-42. doi: 10.1016/j.neo.2014.06.001. Epub 2014 Jul 13.
814 The mutational landscape of mucosal melanoma.Semin Cancer Biol. 2020 Apr;61:139-148. doi: 10.1016/j.semcancer.2019.09.013. Epub 2019 Oct 23.
815 Sirt5 is dispensable for Braf(V600E) -mediated cutaneous melanoma development and growth in vivo.Exp Dermatol. 2019 Jan;28(1):83-85. doi: 10.1111/exd.13845.
816 The sirtuin 6: An overture in skin cancer.Exp Dermatol. 2020 Feb;29(2):124-135. doi: 10.1111/exd.14057. Epub 2019 Dec 29.
817 Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.Cancer Res. 2017 Nov 15;77(22):6226-6239. doi: 10.1158/0008-5472.CAN-17-1965. Epub 2017 Sep 25.
818 Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma.Cancer Chemother Pharmacol. 2010 May;66(1):79-87. doi: 10.1007/s00280-009-1136-0. Epub 2009 Sep 22.
819 Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR.Mol Cell Biochem. 2007 Apr;298(1-2):59-68. doi: 10.1007/s11010-006-9350-0. Epub 2006 Nov 21.
820 SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer. Mol Cancer Ther. 2014 Dec;13(12):2991-3000.
821 Evaluation of Riboflavin Transporters as Targets for Drug Delivery and Theranostics.Front Pharmacol. 2019 Feb 6;10:79. doi: 10.3389/fphar.2019.00079. eCollection 2019.
822 Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter.Cancer Gene Ther. 2011 Feb;18(2):144-52. doi: 10.1038/cgt.2010.66. Epub 2010 Oct 29.
823 Exome sequencing identifies GRIN2A as frequently mutated in melanoma.Nat Genet. 2011 May;43(5):442-6. doi: 10.1038/ng.810. Epub 2011 Apr 15.
824 High SLC7A11 expression in normal skin of melanoma patients.Cancer Epidemiol. 2019 Oct;62:101582. doi: 10.1016/j.canep.2019.101582. Epub 2019 Aug 13.
825 Cutaneous pH landscape as a facilitator of melanoma initiation and progression.Acta Physiol (Oxf). 2019 Jan;225(1):e13105. doi: 10.1111/apha.13105. Epub 2018 Jun 17.
826 SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression.Sci Rep. 2017 Jan 12;7:40585. doi: 10.1038/srep40585.
827 Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy. Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0.
828 Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.Cancer Res. 2009 Apr 1;69(7):2748-56. doi: 10.1158/0008-5472.CAN-08-2690. Epub 2009 Mar 17.
829 Thymine DNA glycosylase as a novel target for melanoma.Oncogene. 2019 May;38(19):3710-3728. doi: 10.1038/s41388-018-0640-2. Epub 2019 Jan 23.
830 Expression and functional role of CRIPTO-1 in cutaneous melanoma.Br J Cancer. 2011 Sep 27;105(7):1030-8. doi: 10.1038/bjc.2011.324. Epub 2011 Aug 23.
831 Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.Am J Dermatopathol. 2019 Apr;41(4):264-272. doi: 10.1097/DAD.0000000000001259.
832 Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.Proc Natl Acad Sci U S A. 1986 Mar;83(5):1261-5. doi: 10.1073/pnas.83.5.1261.
833 Loss of heterozygosity of the thyroid hormone receptor B in posterior uveal melanoma.Melanoma Res. 1993 Dec;3(6):457-61. doi: 10.1097/00008390-199311000-00009.
834 Tumor-Associated Disialylated Glycosphingolipid Antigen-Revealing Antibodies Found in Melanoma Patients' Immunoglobulin Repertoire Suggest a Two-Direction Regulation Mechanism Between Immune B Cells and the Tumor.Front Immunol. 2019 Apr 5;10:650. doi: 10.3389/fimmu.2019.00650. eCollection 2019.
835 Injectable polypeptide hydrogel for dual-delivery of antigen and TLR3 agonist to modulate dendritic cells invivo and enhance potent cytotoxic T-lymphocyte response against melanoma.Biomaterials. 2018 Mar;159:119-129. doi: 10.1016/j.biomaterials.2018.01.004. Epub 2018 Jan 3.
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837 Anti-GD2/4-1BB chimeric antigen receptor T cell therapy for the treatment of Chinese melanoma patients.J Hematol Oncol. 2018 Jan 3;11(1):1. doi: 10.1186/s13045-017-0548-2.
838 Switch to an invasive growth phase in melanoma is associated with tenascin-C, fibronectin, and procollagen-I forming specific channel structures for invasion.J Pathol. 2006 Oct;210(2):181-91. doi: 10.1002/path.2045.
839 Expression of thyrotropin-releasing hormone by human melanoma and nevi.Clin Cancer Res. 2004 Aug 15;10(16):5531-6. doi: 10.1158/1078-0432.CCR-03-0368.
840 TRIM59 loss in M2 macrophages promotes melanoma migration and invasion by upregulating MMP-9 and Madcam1.Aging (Albany NY). 2019 Oct 10;11(19):8623-8641. doi: 10.18632/aging.102351. Epub 2019 Oct 10.
841 Role of TRPM in melanocytes and melanoma.Exp Dermatol. 2012 Sep;21(9):650-4. doi: 10.1111/j.1600-0625.2012.01565.x.
842 Mechanism for Regulation of Melanoma Cell Death via Activation of Thermo-TRPV4 and TRPV2.J Oncol. 2019 Feb 7;2019:7362875. doi: 10.1155/2019/7362875. eCollection 2019.
843 Decreased expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in basal cell carcinomas.Exp Dermatol. 2008 Nov;17(11):908-15. doi: 10.1111/j.1600-0625.2008.00718.x. Epub 2008 Mar 12.
844 TYRP1 mRNA level is stable and MITF-M-independent in drug-nave, vemurafenib- and trametinib-resistant BRAF(V600E) melanoma cells.Arch Dermatol Res. 2020 Jul;312(5):385-392. doi: 10.1007/s00403-019-01995-w. Epub 2019 Oct 17.
845 Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression.Onco Targets Ther. 2019 Jun 13;12:4643-4654. doi: 10.2147/OTT.S205160. eCollection 2019.
846 Lymphangiogenesis and its relationship with lymphatic metastasis and prognosis in malignant melanoma.Anat Rec (Hoboken). 2008 Oct;291(10):1227-35. doi: 10.1002/ar.20736.
847 Loss of miR-155 upregulates WEE1 in metastatic melanoma.Melanoma Res. 2019 Apr;29(2):216-219. doi: 10.1097/CMR.0000000000000545.
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849 The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival.Cell Oncol (Dordr). 2019 Jun;42(3):319-329. doi: 10.1007/s13402-019-00427-1. Epub 2019 Feb 18.
850 Somatic Hypermutation of the YAP Oncogene in a Human Cutaneous Melanoma.Mol Cancer Res. 2019 Jul;17(7):1435-1449. doi: 10.1158/1541-7786.MCR-18-0407. Epub 2019 Mar 4.
851 The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.PLoS One. 2013 Oct 3;8(10):e76550. doi: 10.1371/journal.pone.0076550. eCollection 2013.
852 A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.Medicine (Baltimore). 2019 Mar;98(13):e15003. doi: 10.1097/MD.0000000000015003.
853 Intraprocedural 3D perfusion measurement during chemoembolisation with doxorubicin-eluting beads in liver metastases of malignant melanoma.Eur Radiol. 2018 Apr;28(4):1456-1464. doi: 10.1007/s00330-017-5099-y. Epub 2017 Nov 9.
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855 Bacitracin is a non-competitive inhibitor of porcine M1 family neutral and glutamyl aminopeptidases.Nat Prod Res. 2021 Sep;35(17):2958-2962. doi: 10.1080/14786419.2019.1678611. Epub 2019 Oct 25.
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857 Genetic alterations in primary melanoma in Taiwan.Br J Dermatol. 2020 May;182(5):1205-1213. doi: 10.1111/bjd.18425. Epub 2019 Oct 15.
858 Co-inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo.Oncol Lett. 2019 Jun;17(6):5012-5022. doi: 10.3892/ol.2019.10160. Epub 2019 Mar 19.
859 C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma.FASEB J. 2019 Oct;33(10):11060-11071. doi: 10.1096/fj.201800980RR. Epub 2019 Jul 12.
860 Dermatologic toxicity from novel therapy using antimicrobial peptide LL-37 in melanoma: A detailed examination of the clinicopathologic features.J Cutan Pathol. 2018 Jul;45(7):539-544. doi: 10.1111/cup.13262. Epub 2018 May 16.
861 Association of Baseline Serum Levels of CXCL5 With the Efficacy of Nivolumab in Advanced Melanoma.Front Med (Lausanne). 2019 Apr 26;6:86. doi: 10.3389/fmed.2019.00086. eCollection 2019.
862 B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.Nat Commun. 2019 Sep 13;10(1):4186. doi: 10.1038/s41467-019-12160-2.
863 Upregulation of intratumoral HLA class I and peritumoral Mx1 in ulcerated melanomas.Oncoimmunology. 2019 Sep 6;8(11):e1660121. doi: 10.1080/2162402X.2019.1660121. eCollection 2019.
864 Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.Mol Oncol. 2018 Mar;12(3):287-304. doi: 10.1002/1878-0261.12148. Epub 2018 Jan 28.
865 Unconventional myosin VIIA promotes melanoma progression.J Cell Sci. 2018 Feb 22;131(4):jcs209924. doi: 10.1242/jcs.209924.
866 Chemerin partly mediates tumor-inhibitory effect of all-trans retinoic acid via CMKLR1-dependent natural killer cell recruitment.Immunology. 2019 Jul;157(3):248-256. doi: 10.1111/imm.13065. Epub 2019 May 29.
867 A Mixture of Polyunsaturated Fatty Acids -3 and -6 Reduces Melanoma Growth by Inhibiting Inflammatory Mediators in the Murine Tumor Microenvironment.Int J Mol Sci. 2019 Aug 1;20(15):3765. doi: 10.3390/ijms20153765.
868 DEK oncogene is overexpressed during melanoma progression.Pigment Cell Melanoma Res. 2017 Mar;30(2):194-202. doi: 10.1111/pcmr.12563. Epub 2017 Mar 7.
869 LINC00459 sponging miR-218 to elevate DKK3 inhibits proliferation and invasion in melanoma.Sci Rep. 2019 Dec 16;9(1):19139. doi: 10.1038/s41598-019-55701-x.
870 Evaluation of the Active Targeting of Melanin Granules after Intravenous Injection of Dendronized Nanoparticles.Mol Pharm. 2018 Feb 5;15(2):536-547. doi: 10.1021/acs.molpharmaceut.7b00904. Epub 2018 Jan 17.
871 lncRNA NEAT1 facilitates melanoma cell proliferation, migration, and invasion via regulating miR-495-3p and E2F3.J Cell Physiol. 2019 Nov;234(11):19592-19601. doi: 10.1002/jcp.28559. Epub 2019 Jun 7.
872 Loss of Phd2 cooperates with BRAF(V600E) to drive melanomagenesis.Nat Commun. 2018 Dec 21;9(1):5426. doi: 10.1038/s41467-018-07126-9.
873 ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms.Mol Cancer Ther. 2018 Jan;17(1):222-231. doi: 10.1158/1535-7163.MCT-17-0472. Epub 2017 Oct 20.
874 Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response.Radiol Oncol. 2017 Feb 22;51(1):30-39. doi: 10.1515/raon-2017-0011. eCollection 2017 Mar 1.
875 Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide-Drug Conjugate.J Med Chem. 2018 Mar 8;61(5):2052-2061. doi: 10.1021/acs.jmedchem.7b01837. Epub 2018 Feb 27.
876 Overexpression of Receptor Tyrosine Kinase EphB4 Triggers Tumor Growth and Hypoxia in A375 Melanoma Xenografts: Insights from Multitracer Small Animal Imaging Experiments.Molecules. 2018 Feb 17;23(2):444. doi: 10.3390/molecules23020444.
877 Combined BRAF and HSP90 Inhibition in Patients with Unresectable BRAF (V600E)-Mutant Melanoma.Clin Cancer Res. 2018 Nov 15;24(22):5516-5524. doi: 10.1158/1078-0432.CCR-18-0565. Epub 2018 Apr 19.
878 HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.Mol Cancer Ther. 2018 Feb;17(2):407-418. doi: 10.1158/1535-7163.MCT-17-0288. Epub 2017 Oct 13.
879 TRAF2 and FKBP51 as possible markers for identification of suitable melanoma tumors for tumor necrosis factor- inhibition.Melanoma Res. 2019 Apr;29(2):145-150. doi: 10.1097/CMR.0000000000000553.
880 Intratumoral administration of carboplatin bearing poly (-caprolactone) nanoparticles amalgamated with in situ gel tendered augmented drug delivery, cytotoxicity, and apoptosis in melanoma tumor.Colloids Surf B Biointerfaces. 2018 Jun 1;166:339-348. doi: 10.1016/j.colsurfb.2018.03.009. Epub 2018 Mar 31.
881 Frizzled-10 and cancer progression: Is it a new prognostic marker?.Oncotarget. 2017 Dec 12;9(1):824-830. doi: 10.18632/oncotarget.23159. eCollection 2018 Jan 2.
882 Prioritization and comprehensive analysis of genes associated with melanoma.Oncol Lett. 2019 Jul;18(1):127-136. doi: 10.3892/ol.2019.10284. Epub 2019 Apr 25.
883 High Antigen Processing Machinery component expression in Langerhans cells from melanoma patients' sentinel lymph nodes.Cell Immunol. 2017 Oct;320:29-37. doi: 10.1016/j.cellimm.2017.08.007. Epub 2017 Aug 30.
884 Predominance of triple wild-type and IGF2R mutations in mucosal melanomas.BMC Cancer. 2018 Oct 30;18(1):1054. doi: 10.1186/s12885-018-4977-2.
885 Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression.Int J Oncol. 2018 Dec;53(6):2397-2408. doi: 10.3892/ijo.2018.4579. Epub 2018 Oct 1.
886 Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.Clin Cancer Res. 2012 Oct 1;18(19):5329-40. doi: 10.1158/1078-0432.CCR-12-1632. Epub 2012 Jul 31.
887 Interleukin 4-Induced Gene 1 as an Emerging Regulator of B-Cell Biology and its Role in Cutaneous Melanoma.Crit Rev Immunol. 2019;39(1):39-57. doi: 10.1615/CritRevImmunol.2019030020.
888 Protein kinase C (PKC) regulates p53 localization and melanoma cell survival downstream of integrin v in three-dimensional collagen and in vivo.J Biol Chem. 2012 Aug 24;287(35):29336-47. doi: 10.1074/jbc.M112.341917. Epub 2012 Jul 6.
889 miR-146a Exerts Differential Effects on Melanoma Growth and Metastatization.Mol Cancer Res. 2016 Jun;14(6):548-62. doi: 10.1158/1541-7786.MCR-15-0425-T.
890 Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis.Oncotarget. 2018 Feb 3;9(17):13407-13422. doi: 10.18632/oncotarget.24388. eCollection 2018 Mar 2.
891 KISS1 tumor suppressor restricts angiogenesis of breast cancer brain metastases and sensitizes them to oncolytic virotherapy invitro.Cancer Lett. 2018 Mar 28;417:75-88. doi: 10.1016/j.canlet.2017.12.024. Epub 2017 Dec 18.
892 Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.Nat Commun. 2018 Nov 14;9(1):4774. doi: 10.1038/s41467-018-06649-5.
893 Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression.J Exp Clin Cancer Res. 2018 Jul 28;37(1):176. doi: 10.1186/s13046-018-0842-z.
894 Blockade of Lactate Dehydrogenase-A (LDH-A) Improves Efficacy of Anti-Programmed Cell Death-1 (PD-1) Therapy in Melanoma.Cancers (Basel). 2019 Mar 29;11(4):450. doi: 10.3390/cancers11040450.
895 Increased Expression of GARP in Papillary Thyroid Carcinoma.Endocr Pathol. 2019 Mar;30(1):1-7. doi: 10.1007/s12022-018-9557-0.
896 ERK5 is activated by oncogenic BRAF and promotes melanoma growth.Oncogene. 2018 May;37(19):2601-2614. doi: 10.1038/s41388-018-0164-9. Epub 2018 Feb 27.
897 JNK2 Is Required for the Tumorigenic Properties of Melanoma Cells.ACS Chem Biol. 2019 Jul 19;14(7):1426-1435. doi: 10.1021/acschembio.9b00083. Epub 2019 May 17.
898 Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians.Pharmacogenet Genomics. 2009 Oct;19(10):760-9. doi: 10.1097/FPC.0b013e3283307cd9.
899 NAMPT signaling is critical for the proangiogenic activity of tumor-associated neutrophils.Int J Cancer. 2019 Jan 1;144(1):136-149. doi: 10.1002/ijc.31808. Epub 2018 Oct 30.
900 Dabrafenib inhibits the growth of BRAF-WT cancers through CDK16 and NEK9 inhibition.Mol Oncol. 2018 Jan;12(1):74-88. doi: 10.1002/1878-0261.12152. Epub 2017 Nov 23.
901 A promising redox cycle-based strategy for designing a catechol-type diphenylbutadiene as a potent prooxidative anti-melanoma agent.Free Radic Biol Med. 2019 Jan;130:489-498. doi: 10.1016/j.freeradbiomed.2018.11.018. Epub 2018 Nov 17.
902 Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation.Mol Cell. 2018 Feb 1;69(3):480-492.e7. doi: 10.1016/j.molcel.2018.01.001. Epub 2018 Jan 27.
903 Quantitative assessment of neuropilin-2 as a simple and sensitive diagnostic assay for spitzoid melanocytic lesions.Melanoma Res. 2018 Feb;28(1):71-75. doi: 10.1097/CMR.0000000000000416.
904 Melanoma cases demonstrate increased carrier frequency of phenylketonuria/hyperphenylalanemia mutations.Pigment Cell Melanoma Res. 2018 Jul;31(4):529-533. doi: 10.1111/pcmr.12695. Epub 2018 Mar 12.
905 A novel penicillin derivative induces antitumor effect in melanoma cells.Anticancer Drugs. 2018 Jun;29(5):416-428. doi: 10.1097/CAD.0000000000000611.
906 JAK2, PD-L1, and PD-L2 (9p24.1) amplification in metastatic mucosal and cutaneous melanomas with durable response to immunotherapy.Hum Pathol. 2019 Jun;88:87-91. doi: 10.1016/j.humpath.2018.08.032. Epub 2018 Sep 18.
907 MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.BMC Cancer. 2017 Nov 10;17(1):750. doi: 10.1186/s12885-017-3721-7.
908 miR-625-5p/PKM2 negatively regulates melanoma glycolysis state.J Cell Biochem. 2019 Mar;120(3):2964-2972. doi: 10.1002/jcb.26917. Epub 2018 Nov 30.
909 In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.Mol Cancer Ther. 2019 Sep;18(9):1637-1648. doi: 10.1158/1535-7163.MCT-18-1056. Epub 2019 Jul 3.
910 Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma.Mol Cancer Res. 2018 Mar;16(3):517-527. doi: 10.1158/1541-7786.MCR-17-0197. Epub 2018 Jan 12.
911 All-trans retinoic acid-encapsulated, CD20 antibody-conjugated poly(lactic-co-glycolic acid) nanoparticles effectively target and eliminate melanoma-initiating cells in vitro.Onco Targets Ther. 2018 Sep 25;11:6177-6187. doi: 10.2147/OTT.S169957. eCollection 2018.
912 Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.Br J Cancer. 2018 Feb 20;118(4):495-508. doi: 10.1038/bjc.2017.433. Epub 2017 Dec 12.
913 CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.Cancers (Basel). 2019 Oct 3;11(10):1490. doi: 10.3390/cancers11101490.
914 RAC1(P29S) Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance.Cancer Cell. 2019 Jul 8;36(1):68-83.e9. doi: 10.1016/j.ccell.2019.05.015. Epub 2019 Jun 27.
915 Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis.PLoS Genet. 2018 Sep 6;14(9):e1007589. doi: 10.1371/journal.pgen.1007589. eCollection 2018 Sep.
916 Critical role for nonGAP function of Gs in RGS1mediated promotion of melanoma progression through AKT and ERK phosphorylation.Oncol Rep. 2018 Jun;39(6):2673-2680. doi: 10.3892/or.2018.6341. Epub 2018 Mar 30.
917 On the relationship between VDR, ROR and ROR receptors expression and HIF1- levels in human melanomas.Exp Dermatol. 2019 Sep;28(9):1036-1043. doi: 10.1111/exd.14002. Epub 2019 Aug 8.
918 Ablation of epidermal RXR in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas.BMC Cancer. 2017 Nov 9;17(1):736. doi: 10.1186/s12885-017-3714-6.
919 Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation.Mol Cancer Res. 2018 Jan;16(1):135-146. doi: 10.1158/1541-7786.MCR-17-0292. Epub 2017 Oct 3.
920 SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib.Cancers (Basel). 2019 May 14;11(5):673. doi: 10.3390/cancers11050673.
921 Soluble SLAMF6 Receptor Induces Strong CD8(+) T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo.Cancer Immunol Res. 2018 Feb;6(2):127-138. doi: 10.1158/2326-6066.CIR-17-0383. Epub 2018 Jan 5.
922 Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors.Cell Death Dis. 2018 Feb 27;9(3):325. doi: 10.1038/s41419-018-0340-4.
923 SPARC/osteonectin is involved in metastatic process to the lung during melanoma progression.Virchows Arch. 2014 Sep;465(3):331-8. doi: 10.1007/s00428-014-1616-4. Epub 2014 Jul 4.
924 Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.Cell Rep. 2019 Aug 13;28(7):1879-1893.e7. doi: 10.1016/j.celrep.2019.07.044.
925 Key candidate genes of STAT1 and CXCL10 in melanoma identified by integrated bioinformatical analysis.IUBMB Life. 2019 Oct;71(10):1634-1644. doi: 10.1002/iub.2103. Epub 2019 Jun 19.
926 Stathmin is a potential therapeutic target but not a prognostic marker in melanoma: an immunohistochemical study of 323 melanocytic lesions.Melanoma Res. 2019 Apr;29(2):157-162. doi: 10.1097/CMR.0000000000000550.
927 Sentinel Lymph Node Genes to Predict Prognosis in Node-Positive Melanoma Patients.Ann Surg Oncol. 2017 Jan;24(1):108-116. doi: 10.1245/s10434-016-5575-7. Epub 2016 Sep 23.
928 uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells.Int J Cancer. 2017 Sep 15;141(6):1190-1200. doi: 10.1002/ijc.30817. Epub 2017 Jun 21.
929 Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators.Nat Nanotechnol. 2019 Sep;14(9):891-901. doi: 10.1038/s41565-019-0512-0. Epub 2019 Aug 5.
930 Immune checkpoint inhibitor (anti-CTLA-4, anti-PD-1) therapy alone versus immune checkpoint inhibitor (anti-CTLA-4, anti-PD-1) therapy in combination with anti-RANKL denosumuab in malignant melanoma: a retrospective analysis at a tertiary care center.Melanoma Res. 2018 Aug;28(4):341-347. doi: 10.1097/CMR.0000000000000459.
931 Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies.Mol Cancer Ther. 2018 Jul;17(7):1416-1429. doi: 10.1158/1535-7163.MCT-17-0919. Epub 2018 Apr 27.
932 Specific Targeting of Melanotic Cells with Peptide Ligated Photosensitizers for Photodynamic Therapy.Sci Rep. 2017 Nov 16;7(1):15750. doi: 10.1038/s41598-017-15142-w.
933 A functional approach to understanding the role of NCKX5 in Xenopus pigmentation.PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017.
934 Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8. Mol Genet Genomics. 2011 Jan;285(1):57-65.
935 FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.Cell Death Dis. 2013 Apr 4;4(4):e578. doi: 10.1038/cddis.2013.109.
936 Microarray analysis of phosphatase gene expression in human melanoma.Br J Dermatol. 2005 May;152(5):925-30. doi: 10.1111/j.1365-2133.2005.06454.x.
937 Novel ABCA12 mutations identified in two cases of non-bullous congenital ichthyosiform erythroderma associated with multiple skin malignant neoplasia.J Invest Dermatol. 2007 Nov;127(11):2669-73. doi: 10.1038/sj.jid.5700885. Epub 2007 May 17.
938 Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins. Cancer Discov. 2018 Aug;8(8):1006-1025.
939 Diagnostic and prognostic value of glucose transporters in melanocytic lesions.Melanoma Res. 2019 Dec;29(6):603-611. doi: 10.1097/CMR.0000000000000626.
940 The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung.Oncotarget. 2017 Apr 11;8(15):25066-25079. doi: 10.18632/oncotarget.15339.
941 On the role of classical and novel forms of vitamin D in melanoma progression and management.J Steroid Biochem Mol Biol. 2018 Mar;177:159-170. doi: 10.1016/j.jsbmb.2017.06.013. Epub 2017 Jul 1.
942 A polymorphic GGC repeat in the NPAS2 gene and its association with melanoma.Exp Biol Med (Maywood). 2017 Sep;242(15):1553-1558. doi: 10.1177/1535370217724093. Epub 2017 Aug 11.
943 Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1(+) Melanoma.Cancer Res. 2019 Apr 15;79(8):1799-1809. doi: 10.1158/0008-5472.CAN-18-1500. Epub 2019 Apr 15.
944 Post-translational modification of HINT1 mediates activation of MITF transcriptional activity in human melanoma cells.Oncogene. 2017 Aug 17;36(33):4732-4738. doi: 10.1038/onc.2017.81. Epub 2017 Apr 10.
945 Lentivirus-mediated downregulation of MAT2B inhibits cell proliferation and induces apoptosis in melanoma.Int J Oncol. 2016 Sep;49(3):981-90. doi: 10.3892/ijo.2016.3603. Epub 2016 Jul 5.
946 Silencing of metallothionein 1A gene in melanoma.J Dermatol Sci. 2017 Nov;88(2):232-237. doi: 10.1016/j.jdermsci.2017.07.009. Epub 2017 Jul 21.
947 Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression.Int J Mol Sci. 2017 Sep 7;18(9):1924. doi: 10.3390/ijms18091924.
948 Analysis of nicotinamide N-methyltransferase in oral malignant melanoma and potential prognostic significance.Melanoma Res. 2019 Apr;29(2):151-156. doi: 10.1097/CMR.0000000000000548.
949 Clinical-Scale Production of CAR-T Cells for the Treatment of Melanoma Patients by mRNA Transfection of a CSPG4-Specific CAR under Full GMP Compliance.Cancers (Basel). 2019 Aug 16;11(8):1198. doi: 10.3390/cancers11081198.
950 In vivo 6-thioguanine-resistant T cells from melanoma patients have public TCR and share TCR beta amino acid sequences with melanoma-reactive T cells.J Immunol Methods. 2011 Feb 28;365(1-2):76-86. doi: 10.1016/j.jim.2010.12.007. Epub 2010 Dec 21.
951 Proinvasion metastasis drivers in early-stage melanoma are oncogenes.Cancer Cell. 2011 Jul 12;20(1):92-103. doi: 10.1016/j.ccr.2011.05.025.
952 Clinical implications of ALDH1A1 and ALDH1A3 mRNA expression in melanoma subtypes.Chem Biol Interact. 2019 Dec 1;314:108822. doi: 10.1016/j.cbi.2019.108822. Epub 2019 Sep 30.
953 Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells.Int J Cancer. 2000 Nov 15;88(4):547-53. doi: 10.1002/1097-0215(20001115)88:4<547::aid-ijc5>3.0.co;2-l.
954 Differential biological effects of 1,25-dihydroxyVitamin D3 on melanoma cell lines in vitro.J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):375-9. doi: 10.1016/j.jsbmb.2004.03.002.
955 Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival.Int J Cancer. 2019 Nov 15;145(10):2619-2628. doi: 10.1002/ijc.32194. Epub 2019 Feb 20.
956 Melanoma risk for CDKN2A mutation carriers who are relatives of population-based case carriers in Australia and the UK.J Med Genet. 2011 Apr;48(4):266-72. doi: 10.1136/jmg.2010.086538. Epub 2011 Feb 15.
957 The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.Br J Cancer. 2009 May 19;100(10):1687-96. doi: 10.1038/sj.bjc.6605042.
958 Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma.J Invest Dermatol. 2019 May;139(5):1118-1126. doi: 10.1016/j.jid.2018.10.038. Epub 2018 Nov 16.
959 The characterization of the invasion phenotype of uveal melanoma tumour cells shows the presence of MUC18 and HMG-1 metastasis markers and leads to the identification of DJ-1 as a potential serum biomarker.Int J Cancer. 2006 Sep 1;119(5):1014-22. doi: 10.1002/ijc.21942.
960 SCL gene in human tumors.Leukemia. 1992 Jul;6(7):623-5.
961 Lipocalin-type prostaglandin D synthase-derived PGD(2) attenuates malignant properties of tumor endothelial cells.J Pathol. 2018 Jan;244(1):84-96. doi: 10.1002/path.4993. Epub 2017 Nov 10.
962 Combining Type I Interferons and 5-Aza-2'-Deoxycitidine to Improve Anti-Tumor Response against Melanoma.J Invest Dermatol. 2017 Jan;137(1):159-169. doi: 10.1016/j.jid.2016.08.024. Epub 2016 Sep 10.
963 An Ancient, Unified Mechanism for Metformin Growth Inhibition in C.elegans and Cancer.Cell. 2016 Dec 15;167(7):1705-1718.e13. doi: 10.1016/j.cell.2016.11.055.
964 Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.PLoS One. 2016 May 12;11(5):e0155660. doi: 10.1371/journal.pone.0155660. eCollection 2016.
965 Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.J Biol Chem. 2016 Oct 14;291(42):21869-21879. doi: 10.1074/jbc.M115.712166. Epub 2016 Aug 18.
966 Biological properties of melanoma and endothelial cells after plasmid AMEP gene electrotransfer depend on integrin quantity on cells.J Membr Biol. 2013 Nov;246(11):803-19. doi: 10.1007/s00232-013-9550-y. Epub 2013 May 7.
967 ADAR1-mediated regulation of melanoma invasion.Nat Commun. 2018 May 31;9(1):2154. doi: 10.1038/s41467-018-04600-2.
968 BRAF Fusion as a Novel Mechanism of Acquired Resistance to Vemurafenib in BRAF(V600E) Mutant Melanoma.Clin Cancer Res. 2017 Sep 15;23(18):5631-5638. doi: 10.1158/1078-0432.CCR-16-0758. Epub 2017 May 24.
969 AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.Melanoma Res. 2016 Apr;26(2):108-16. doi: 10.1097/CMR.0000000000000228.
970 Inflammation-related induction of absent in melanoma 2 (AIM2) in vascular cells and atherosclerotic lesions suggests a role in vascular pathogenesis.J Vasc Surg. 2014 Mar;59(3):794-803. doi: 10.1016/j.jvs.2013.03.048. Epub 2013 Jun 21.
971 Targeting protein kinase-b3 (akt3) signaling in melanoma.Expert Opin Ther Targets. 2017 Mar;21(3):273-290. doi: 10.1080/14728222.2017.1279147. Epub 2017 Jan 16.
972 Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.Mol Cell. 2017 Nov 16;68(4):731-744.e9. doi: 10.1016/j.molcel.2017.11.004.
973 Development of an HTS-Compatible Assay for Discovery of Melanoma-Related Microphthalmia Transcription Factor Disruptors Using AlphaScreen Technology.SLAS Discov. 2017 Jan;22(1):58-66. doi: 10.1177/1087057116675274. Epub 2016 Nov 11.
974 Multiple pro-tumorigenic functions of the human minor Histocompatibility Antigen-1 (HA-1) in melanoma progression.J Dermatol Sci. 2017 Nov;88(2):216-224. doi: 10.1016/j.jdermsci.2017.07.004. Epub 2017 Jul 8.
975 TIM-4 Identifies IFN--Expressing Proinflammatory B Effector 1 Cells That Promote Tumor and Allograft Rejection.J Immunol. 2017 Oct 1;199(7):2585-2595. doi: 10.4049/jimmunol.1602107. Epub 2017 Aug 28.
976 Patient with anomalous skin pigmentation expands the phenotype of ARID2 loss-of-function disorder, a SWI/SNF-related intellectual disability.Am J Med Genet A. 2019 May;179(5):808-812. doi: 10.1002/ajmg.a.61075. Epub 2019 Mar 5.
977 Targeted silencing of the ADP-ribosyltransferase 3 gene inhibits the migration ability of melanoma cells.Oncol Lett. 2018 May;15(5):7053-7059. doi: 10.3892/ol.2018.8252. Epub 2018 Mar 13.
978 Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells.Oncogene. 2019 Feb;38(8):1282-1295. doi: 10.1038/s41388-018-0500-0. Epub 2018 Sep 25.
979 Identification of key candidate genes involved in melanoma metastasis.Mol Med Rep. 2019 Aug;20(2):903-914. doi: 10.3892/mmr.2019.10314. Epub 2019 May 30.
980 Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study.Cancer Med. 2016 Nov;5(11):3336-3345. doi: 10.1002/cam4.929. Epub 2016 Oct 17.
981 Fucosylation Enhances the Efficacy of Adoptively Transferred Antigen-Specific Cytotoxic T Lymphocytes.Clin Cancer Res. 2019 Apr 15;25(8):2610-2620. doi: 10.1158/1078-0432.CCR-18-1527. Epub 2019 Jan 15.
982 ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI(3, 5)P2-mediated scaffolding function.Hum Mol Genet. 2017 May 1;26(9):1656-1669. doi: 10.1093/hmg/ddx070.
983 The plasma membrane Ca(2+) pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.Int J Cancer. 2017 Jun 15;140(12):2758-2770. doi: 10.1002/ijc.30503. Epub 2016 Nov 17.
984 UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor and interleukin 6.Biochem Biophys Res Commun. 2014 Mar 7;445(2):504-10. doi: 10.1016/j.bbrc.2014.02.038. Epub 2014 Feb 15.
985 The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis.Clin Cancer Res. 2016 Jul 1;22(13):3268-80. doi: 10.1158/1078-0432.CCR-15-2066. Epub 2016 Jan 5.
986 A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3.Biochim Biophys Acta. 2016 Aug;1860(8):1753-63. doi: 10.1016/j.bbagen.2016.04.005. Epub 2016 Apr 9.
987 Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells.Oncogene. 2012 May 10;31(19):2461-70. doi: 10.1038/onc.2011.425. Epub 2011 Sep 26.
988 BIK is involved in BRAF/MEK inhibitor induced apoptosis in melanoma cell lines.Cancer Lett. 2017 Sep 28;404:70-78. doi: 10.1016/j.canlet.2017.07.005. Epub 2017 Jul 15.
989 BNIP3 contributes to the glutamine-driven aggressive behavior of melanoma cells.Biol Chem. 2019 Jan 28;400(2):187-193. doi: 10.1515/hsz-2018-0208.
990 BPTF transduces MITF-driven prosurvival signals in melanoma cells.Proc Natl Acad Sci U S A. 2016 May 31;113(22):6254-8. doi: 10.1073/pnas.1606027113. Epub 2016 May 16.
991 Expression of breast cancer metastasis suppressor-1, BRMS-1, in human breast cancer and the biological impact of BRMS-1 on the migration of breast cancer cells.Anticancer Res. 2014 Mar;34(3):1417-26.
992 Genetic Variants in WNT2B and BTRC Predict Melanoma Survival.J Invest Dermatol. 2017 Aug;137(8):1749-1756. doi: 10.1016/j.jid.2017.04.023. Epub 2017 May 10.
993 Cul1 promotes melanoma cell proliferation by promoting DEPTOR degradation and enhancing cap-dependent translation.Oncol Rep. 2016 Feb;35(2):1049-56. doi: 10.3892/or.2015.4442. Epub 2015 Nov 23.
994 CAP2 is a Valuable Biomarker for Diagnosis and Prognostic in Patients with Gastric Cancer.Pathol Oncol Res. 2020 Jan;26(1):273-279. doi: 10.1007/s12253-018-0450-4. Epub 2018 Jul 26.
995 Type 1 diabetes mellitus caused by treatment with low-dose interferon- in a melanoma patient.Melanoma Res. 2017 Oct;27(5):516-518. doi: 10.1097/CMR.0000000000000381.
996 Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model.Front Pharmacol. 2017 Jul 7;8:319. doi: 10.3389/fphar.2017.00319. eCollection 2017.
997 High CCL27 immunoreactivity in 'supratumoral' epidermis correlates with better prognosis in patients with cutaneous malignant melanoma.J Clin Pathol. 2017 Jan;70(1):15-19. doi: 10.1136/jclinpath-2015-203537. Epub 2016 Jun 20.
998 WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition.J Biol Chem. 2019 Apr 5;294(14):5261-5280. doi: 10.1074/jbc.RA118.006122. Epub 2019 Feb 5.
999 Potential role of cyclin F mRNA expression in the survival of skin melanoma patients: Comprehensive analysis of the pathways altered due to cyclin F upregulation.Oncol Rep. 2018 Jul;40(1):123-144. doi: 10.3892/or.2018.6435. Epub 2018 May 16.
1000 Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets.Theranostics. 2019 Aug 12;9(20):5797-5809. doi: 10.7150/thno.35059. eCollection 2019.
1001 Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications.Theranostics. 2017 Aug 22;7(14):3585-3594. doi: 10.7150/thno.21471. eCollection 2017.
1002 CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.Oncotarget. 2017 Dec 7;8(69):114328-114343. doi: 10.18632/oncotarget.23107. eCollection 2017 Dec 26.
1003 The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.Sci Transl Med. 2016 Dec 14;8(369):369ra177. doi: 10.1126/scitranslmed.aai9188.
1004 MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene.Tumour Biol. 2016 Oct;37(10):13941-13950. doi: 10.1007/s13277-016-5271-z. Epub 2016 Aug 4.
1005 Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RAR signaling.Mol Cancer Res. 2013 Oct;11(10):1166-78. doi: 10.1158/1541-7786.MCR-13-0006. Epub 2013 Jul 12.
1006 Vitamin D receptor polymorphisms and melanoma.Oncol Lett. 2019 May;17(5):4162-4169. doi: 10.3892/ol.2018.9733. Epub 2018 Nov 19.
1007 Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.Nat Commun. 2017 Dec 21;8(1):2249. doi: 10.1038/s41467-017-02353-y.
1008 Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.Nat Genet. 2015 May;47(5):486-95. doi: 10.1038/ng.3275. Epub 2015 Apr 13.
1009 Silencing of CerS6 increases the invasion and glycolysis of melanoma WM35, WM451 and SK28 cell lines via increased GLUT1-induced downregulation of WNT5A.Oncol Rep. 2016 May;35(5):2907-15. doi: 10.3892/or.2016.4646. Epub 2016 Mar 2.
1010 MicroRNA-dependent regulation of cKit in cutaneous melanoma.Biochem Biophys Res Commun. 2009 Feb 13;379(3):790-4. doi: 10.1016/j.bbrc.2008.12.152. Epub 2009 Jan 4.
1011 Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, aCandidate Melanoma Suppressor Function.J Invest Dermatol. 2017 Oct;137(10):2197-2207. doi: 10.1016/j.jid.2017.05.030. Epub 2017 Jun 22.
1012 Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2.Oncol Lett. 2018 Feb;15(2):2413-2418. doi: 10.3892/ol.2017.7592. Epub 2017 Dec 12.
1013 CKS1 expression in melanocytic nevi and melanoma.Oncotarget. 2017 Dec 23;9(3):4173-4187. doi: 10.18632/oncotarget.23648. eCollection 2018 Jan 9.
1014 MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.J Invest Dermatol. 2016 Feb;136(2):453-463. doi: 10.1016/j.jid.2015.11.012. Epub 2015 Nov 20.
1015 The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.Oncogene. 2019 Dec;38(50):7491-7503. doi: 10.1038/s41388-019-0961-9. Epub 2019 Aug 21.
1016 An engineered PD-1-based and MMP-2/9-oriented fusion protein exerts potent antitumor effects against melanoma.BMB Rep. 2018 Nov;51(11):572-577. doi: 10.5483/BMBRep.2018.51.11.076.
1017 Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.Nat Commun. 2016 Nov 18;7:13418. doi: 10.1038/ncomms13418.
1018 Targeting CPT1A enhances metabolic therapy in human melanoma cells with the BRAF V600E mutation.Int J Biochem Cell Biol. 2016 Dec;81(Pt A):76-81. doi: 10.1016/j.biocel.2016.10.019. Epub 2016 Oct 25.
1019 Prevalence of BRAF V600E mutation in Chinese melanoma patients: large scale analysis of BRAF and NRAS mutations in a 432-case cohort.Eur J Cancer. 2012 Jan;48(1):94-100. doi: 10.1016/j.ejca.2011.06.056. Epub 2011 Jul 23.
1020 Seroreactivity against MAGE-A and LAGE-1 proteins in melanoma patients.Br J Dermatol. 2003 Aug;149(2):282-8. doi: 10.1046/j.1365-2133.2003.05410.x.
1021 CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.J Invest Dermatol. 2013 May;133(5):1294-301. doi: 10.1038/jid.2012.487. Epub 2013 Jan 10.
1022 Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif.Cell Rep. 2016 Dec 13;17(11):2865-2872. doi: 10.1016/j.celrep.2016.11.055.
1023 Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.Oncotarget. 2016 Mar 22;7(12):15065-92. doi: 10.18632/oncotarget.7604.
1024 Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.Mol Cell Proteomics. 2020 Jan;19(1):50-64. doi: 10.1074/mcp.RA119.001811. Epub 2019 Nov 2.
1025 The Chemokine Receptor CXCR6 Evokes Reverse Signaling via the Transmembrane Chemokine CXCL16.Int J Mol Sci. 2017 Jul 8;18(7):1468. doi: 10.3390/ijms18071468.
1026 Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants.Int J Cancer. 2004 May 20;110(1):15-21. doi: 10.1002/ijc.20078.
1027 Overexpression of mRNA-decapping enzyme 1a predicts disease-specific survival in malignant melanoma.Melanoma Res. 2018 Feb;28(1):30-36. doi: 10.1097/CMR.0000000000000406.
1028 Prognostic Value of Dynactin mRNA Expression in Cutaneous Melanoma.Med Sci Monit. 2018 Jun 4;24:3752-3763. doi: 10.12659/MSM.910566.
1029 Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair.Oncotarget. 2016 Sep 20;7(38):60940-60953. doi: 10.18632/oncotarget.10902.
1030 Polymorphisms in the p27kip-1 and prohibitin genes denote novel genes associated with melanoma risk in Brazil, a high ultraviolet index region.Melanoma Res. 2013 Jun;23(3):231-6. doi: 10.1097/CMR.0b013e3283612483.
1031 The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma.Cell Rep. 2019 Jun 18;27(12):3573-3586.e7. doi: 10.1016/j.celrep.2019.05.069.
1032 DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2.Mol Cells. 2017 May 31;40(5):322-330. doi: 10.14348/molcells.2017.0001. Epub 2017 May 2.
1033 Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition.Oncogene. 2017 Jun 8;36(23):3334-3345. doi: 10.1038/onc.2016.486. Epub 2017 Jan 16.
1034 Pulmonary administration of curcumin inhibits B16F10 melanoma lung metastasis and invasion in mice.Cancer Chemother Pharmacol. 2018 Aug;82(2):265-273. doi: 10.1007/s00280-018-3616-6. Epub 2018 Jun 4.
1035 Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome.Oncotarget. 2016 Jul 19;7(29):46492-46508. doi: 10.18632/oncotarget.10216.
1036 The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis.Ann Surg. 2019 Oct;270(4):712-722. doi: 10.1097/SLA.0000000000003522.
1037 ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma.Cancers (Basel). 2018 Dec 20;11(1):3. doi: 10.3390/cancers11010003.
1038 Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes.J Invest Dermatol. 2015 Sep;135(9):2266-2272. doi: 10.1038/jid.2015.138. Epub 2015 Apr 7.
1039 Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis.Oncotarget. 2017 Jan 24;8(4):6085-6101. doi: 10.18632/oncotarget.14042.
1040 Profiling Optimal Conditions for Capturing EDEM Proteins Complexes in Melanoma Using Mass Spectrometry.Adv Exp Med Biol. 2019;1140:155-167. doi: 10.1007/978-3-030-15950-4_9.
1041 Inhibition of p38/MK2 Signaling Prevents Vascular Invasion of Melanoma.J Invest Dermatol. 2020 Apr;140(4):878-890.e5. doi: 10.1016/j.jid.2019.08.451. Epub 2019 Oct 14.
1042 Endothelin-3 is produced by metastatic melanoma cells and promotes melanoma cell survival.J Cutan Med Surg. 2008 Mar-Apr;12(2):64-70. doi: 10.2310/7750.2008.06164.
1043 SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas.Acta Neuropathol Commun. 2016 Jan 15;4:5. doi: 10.1186/s40478-016-0272-0.
1044 Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.Genes Dev. 2017 Jan 1;31(1):18-33. doi: 10.1101/gad.290940.116. Epub 2017 Jan 17.
1045 Knockdown of EIF3D suppresses proliferation of human melanoma cells through G2/M phase arrest.Biotechnol Appl Biochem. 2015 Sep-Oct;62(5):615-20. doi: 10.1002/bab.1305. Epub 2015 Jan 12.
1046 Cancer Targeted Gene Therapy for Inhibition of Melanoma Lung Metastasis with eIF3i shRNA Loaded Liposomes.Mol Pharm. 2020 Jan 6;17(1):229-238. doi: 10.1021/acs.molpharmaceut.9b00943. Epub 2019 Dec 10.
1047 Translational control of tumor immune escape via the eIF4F-STAT1-PD-L1 axis in melanoma.Nat Med. 2018 Dec;24(12):1877-1886. doi: 10.1038/s41591-018-0217-1. Epub 2018 Oct 29.
1048 Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway.Oncogene. 2016 Mar 3;35(9):1170-9. doi: 10.1038/onc.2015.175. Epub 2015 Jun 1.
1049 XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro), and GSTP1 (Ile105Val) polymorphisms in prognosis of cutaneous melanoma.Tumour Biol. 2016 Mar;37(3):3163-71. doi: 10.1007/s13277-015-4123-6. Epub 2015 Oct 2.
1050 Current evidences on the XPG Asp1104His polymorphism and melanoma susceptibility: a meta-analysis based on case-control studies.Mol Genet Genomics. 2015 Feb;290(1):273-9. doi: 10.1007/s00438-014-0917-2. Epub 2014 Sep 18.
1051 Altered Expression and Splicing of ESRP1 in Malignant Melanoma Correlates with Epithelial-Mesenchymal Status and Tumor-Associated Immune Cytolytic Activity.Cancer Immunol Res. 2016 Jun;4(6):552-61. doi: 10.1158/2326-6066.CIR-15-0255. Epub 2016 Apr 4.
1052 Ipilimumab in melanoma.Expert Rev Anticancer Ther. 2016 Aug;16(8):811-26. doi: 10.1080/14737140.2016.1211936. Epub 2016 Jul 25.
1053 miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1.Oncotarget. 2015 Aug 7;6(22):19006-16. doi: 10.18632/oncotarget.4147.
1054 Exonuclease 1 (EXO1) gene variation and melanoma risk.DNA Repair (Amst). 2012 Mar 1;11(3):304-9. doi: 10.1016/j.dnarep.2011.12.005. Epub 2012 Jan 9.
1055 Eyes absent gene (EYA1) is a pathogenic driver and a therapeutic target for melanoma.Oncotarget. 2017 Sep 27;8(62):105081-105092. doi: 10.18632/oncotarget.21352. eCollection 2017 Dec 1.
1056 Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1).J Biol Chem. 2018 Jul 20;293(29):11401-11414. doi: 10.1074/jbc.RA118.003616. Epub 2018 Jun 5.
1057 Expression of kindlin-3 in melanoma cells impedes cell migration and metastasis.Cell Adh Migr. 2017 Sep 3;11(5-6):419-433. doi: 10.1080/19336918.2016.1243645. Epub 2016 Nov 2.
1058 FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo.Oncotarget. 2017 Sep 23;8(50):87750-87762. doi: 10.18632/oncotarget.21184. eCollection 2017 Oct 20.
1059 FHOD1 formin is upregulated in melanomas and modifies proliferation and tumor growth.Exp Cell Res. 2017 Jan 1;350(1):267-278. doi: 10.1016/j.yexcr.2016.12.004. Epub 2016 Dec 2.
1060 Expression of mitochondrial dynamics markers during melanoma progression: Comparative study of head and neck cutaneous and mucosal melanomas.J Oral Pathol Med. 2019 May;48(5):373-381. doi: 10.1111/jop.12855. Epub 2019 Apr 10.
1061 Aberrant expression of FLI-1 in melanoma.J Cutan Pathol. 2017 Sep;44(9):790-793. doi: 10.1111/cup.12979. Epub 2017 Jul 10.
1062 The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells.Cell Death Dis. 2017 Nov 16;8(11):e3169. doi: 10.1038/cddis.2017.521.
1063 FAD104, a Regulator of Adipogenesis and Osteogenesis, Interacts with the C-Terminal Region of STAT3 and Represses Malignant Transformation of Melanoma Cells.Biol Pharm Bull. 2016 May 1;39(5):849-55. doi: 10.1248/bpb.b15-01026. Epub 2016 Mar 4.
1064 Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents.Cancer Res. 2004 Oct 15;64(20):7386-94. doi: 10.1158/0008-5472.CAN-04-1640.
1065 Regulation of Cancer Stem Cell Self-Renewal by HOXB9 Antagonizes Endoplasmic Reticulum Stress-Induced Melanoma Cell Apoptosis via the miR-765-FOXA2 Axis.J Invest Dermatol. 2018 Jul;138(7):1609-1619. doi: 10.1016/j.jid.2018.01.023. Epub 2018 Feb 3.
1066 FOXD3 Promotes PAX3 Expression in Melanoma Cells.J Cell Biochem. 2016 Feb;117(2):533-41. doi: 10.1002/jcb.25306. Epub 2015 Sep 1.
1067 The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.PLoS One. 2018 Jun 20;13(6):e0199128. doi: 10.1371/journal.pone.0199128. eCollection 2018.
1068 A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.Cancer Cell. 2017 Jun 12;31(6):804-819.e7. doi: 10.1016/j.ccell.2017.05.007.
1069 Immunohistochemical Expression of FXR1 in Canine Normal Tissues and Melanomas.J Histochem Cytochem. 2018 Aug;66(8):585-593. doi: 10.1369/0022155418766292. Epub 2018 Apr 2.
1070 Transcriptional response to hypoxic stress in melanoma and prognostic potential of GBE1 and BNIP3.Oncotarget. 2017 Oct 30;8(65):108786-108801. doi: 10.18632/oncotarget.22150. eCollection 2017 Dec 12.
1071 Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma.Oncol Lett. 2018 May;15(5):7914-7922. doi: 10.3892/ol.2018.8306. Epub 2018 Mar 20.
1072 Genetic variants in the vitamin D pathway genes VDBP and RXRA modulate cutaneous melanoma disease-specific survival.Pigment Cell Melanoma Res. 2016 Mar;29(2):176-85. doi: 10.1111/pcmr.12437. Epub 2016 Jan 29.
1073 GINS2 regulates matrix metallopeptidase 9 expression and cancer stem cell property in human triple negative Breast cancer.Biomed Pharmacother. 2016 Dec;84:1568-1574. doi: 10.1016/j.biopha.2016.10.032. Epub 2016 Nov 6.
1074 Identifying and targeting determinants of melanoma cellular invasion.Oncotarget. 2016 Jul 5;7(27):41186-41202. doi: 10.18632/oncotarget.9227.
1075 Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools.Oncogene. 2017 Jan 5;36(1):84-96. doi: 10.1038/onc.2016.178. Epub 2016 May 16.
1076 A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.J Natl Cancer Inst. 2018 Dec 1;110(12):1380-1385. doi: 10.1093/jnci/djy058.
1077 Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma.PLoS One. 2019 Jun 14;14(6):e0218067. doi: 10.1371/journal.pone.0218067. eCollection 2019.
1078 Glutathione S-transferase M1/T1 genotype and melanoma in a Southern Italian population: a case-control study.G Ital Dermatol Venereol. 2016 Apr;151(2):140-4. Epub 2015 Jan 14.
1079 Validation of the Chowdhury overall survival score in patients with melanoma brain metastasis treated with Gamma Knife Radiosurgery.J Neurooncol. 2018 Jun;138(2):391-399. doi: 10.1007/s11060-018-2808-6. Epub 2018 Feb 22.
1080 Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer.Oncotarget. 2016 Mar 8;7(10):11412-23. doi: 10.18632/oncotarget.7194.
1081 Immunotherapy in mucosal melanoma: a case report and review of the literature.Oncotarget. 2018 Apr 3;9(25):17971-17977. doi: 10.18632/oncotarget.24727. eCollection 2018 Apr 3.
1082 HLA class I and class II frequencies in patients with cutaneous malignant melanoma from southeastern Spain: the role of HLA-C in disease prognosis.Immunogenetics. 2006 Jan;57(12):926-33. doi: 10.1007/s00251-005-0065-2. Epub 2005 Dec 20.
1083 Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase.PLoS One. 2017 Jan 20;12(1):e0170054. doi: 10.1371/journal.pone.0170054. eCollection 2017.
1084 HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors. Cancer Res. 2016 May 1;76(9):2720-30. doi: 10.1158/0008-5472.CAN-15-2137. Epub 2016 Mar 16.
1085 HSP105 recruits protein phosphatase 2A to dephosphorylate -catenin.Mol Cell Biol. 2015 Apr;35(8):1390-400. doi: 10.1128/MCB.01307-14. Epub 2015 Feb 2.
1086 Inhibitor of DNA Binding 4 (ID4) is highly expressed in human melanoma tissues and may function to restrict normal differentiation of melanoma cells.PLoS One. 2015 Feb 2;10(2):e0116839. doi: 10.1371/journal.pone.0116839. eCollection 2015.
1087 High GILT Expression and an Active and Intact MHC Class II Antigen Presentation Pathway Are Associated with Improved Survival in Melanoma.J Immunol. 2019 Nov 15;203(10):2577-2587. doi: 10.4049/jimmunol.1900476. Epub 2019 Oct 7.
1088 Low prevalence of RAS-RAF-activating mutations in Spitz melanocytic nevi compared with other melanocytic lesions.J Cutan Pathol. 2007 Jun;34(6):448-55. doi: 10.1111/j.1600-0560.2006.00646.x.
1089 EWI-2 negatively regulates TGF- signaling leading to altered melanoma growth and metastasis.Cell Res. 2015 Mar;25(3):370-85. doi: 10.1038/cr.2015.17. Epub 2015 Feb 6.
1090 MEK inhibition and immune responses in advanced melanoma.Oncoimmunology. 2017 Aug 10;6(8):e1335843. doi: 10.1080/2162402X.2017.1335843. eCollection 2017.
1091 The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma.JCI Insight. 2018 Jul 26;3(14):e120422. doi: 10.1172/jci.insight.120422. eCollection 2018 Jul 26.
1092 The positive feedback loop between ILF3 and lncRNA ILF3-AS1 promotes melanoma proliferation, migration, and invasion.Cancer Manag Res. 2018 Dec 11;10:6791-6802. doi: 10.2147/CMAR.S186777. eCollection 2018.
1093 Phosphorylation of the tumor suppressor p33(ING1b) at Ser-126 influences its protein stability and proliferation of melanoma cells.FASEB J. 2007 Nov;21(13):3705-16. doi: 10.1096/fj.07-8069com. Epub 2007 Jun 21.
1094 INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma.Genes Dev. 2016 Jun 15;30(12):1440-53. doi: 10.1101/gad.277178.115.
1095 Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.Biosci Rep. 2017 Feb 10;37(1):BSR20160432. doi: 10.1042/BSR20160432. Print 2017 Feb 28.
1096 The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma.Sci Rep. 2018 Jul 19;8(1):10902. doi: 10.1038/s41598-018-27643-3.
1097 Combination of Asiatic Acid and Naringenin Modulates NK Cell Anti-cancer Immunity by Rebalancing Smad3/Smad7 Signaling.Mol Ther. 2018 Sep 5;26(9):2255-2266. doi: 10.1016/j.ymthe.2018.06.016. Epub 2018 Jun 22.
1098 Silencing of interferon regulatory factor gene 6 in melanoma.PLoS One. 2017 Sep 6;12(9):e0184444. doi: 10.1371/journal.pone.0184444. eCollection 2017.
1099 Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts.J Cell Mol Med. 2017 Nov;21(11):3087-3099. doi: 10.1111/jcmm.13221. Epub 2017 May 30.
1100 Downregulation of miR-493 promoted melanoma proliferation by suppressing IRS4 expression.Tumour Biol. 2017 May;39(5):1010428317701640. doi: 10.1177/1010428317701640.
1101 MicroRNA-125b suppresses the epithelial-mesenchymal transition and cell invasion by targeting ITGA9 in melanoma.Tumour Biol. 2016 May;37(5):5941-9. doi: 10.1007/s13277-015-4409-8. Epub 2015 Nov 23.
1102 KSRP modulates melanoma growth and efficacy of vemurafenib.Biochim Biophys Acta Gene Regul Mech. 2019 Aug;1862(8):759-770. doi: 10.1016/j.bbagrm.2019.06.005. Epub 2019 Jun 30.
1103 Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells.J Nat Prod. 2017 Jul 28;80(7):1981-1991. doi: 10.1021/acs.jnatprod.6b01129. Epub 2017 Jun 15.
1104 LIMD2 targeted by miR?4a promotes the proliferation and invasion of nonsmall cell lung cancer cells.Mol Med Rep. 2018 Nov;18(5):4760-4766. doi: 10.3892/mmr.2018.9464. Epub 2018 Sep 6.
1105 Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks.Genome Med. 2017 Aug 30;9(1):80. doi: 10.1186/s13073-017-0464-7.
1106 LOXL3 Function Beyond Amino Oxidase and Role in Pathologies, Including Cancer.Int J Mol Sci. 2019 Jul 23;20(14):3587. doi: 10.3390/ijms20143587.
1107 Multifocal gastric adenocarcinoma in a patient with LRBA deficiency.Orphanet J Rare Dis. 2017 Jul 18;12(1):131. doi: 10.1186/s13023-017-0682-5.
1108 Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling.J Exp Clin Cancer Res. 2018 Aug 6;37(1):184. doi: 10.1186/s13046-018-0844-x.
1109 Melanoma LAMP-2C Modulates Tumor Growth and Autophagy.Front Cell Dev Biol. 2018 Aug 29;6:101. doi: 10.3389/fcell.2018.00101. eCollection 2018.
1110 Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior.Elife. 2018 Apr 12;7:e34362. doi: 10.7554/eLife.34362.
1111 MicroRNA-338-3p suppresses cell proliferation, migration and invasion in human malignant melanoma by targeting MACC1.Exp Ther Med. 2019 Aug;18(2):997-1004. doi: 10.3892/etm.2019.7644. Epub 2019 Jun 4.
1112 Giant Pediatric Rhabdoid Meningioma Associated with a Germline BAP1 Pathogenic Variation: A Rare Clinical Case.World Neurosurg. 2018 Nov;119:402-415. doi: 10.1016/j.wneu.2018.06.227. Epub 2018 Jul 6.
1113 Oncogenic BRAFV600E induces expression of neuronal differentiation marker MAP2 in melanoma cells by promoter demethylation and down-regulation of transcription repressor HES1.J Biol Chem. 2010 Jan 1;285(1):242-54. doi: 10.1074/jbc.M109.068668. Epub 2009 Oct 30.
1114 Pro-necrotic molecules impact local immunosurveillance in human breast cancer.Oncoimmunology. 2017 Apr 17;6(4):e1299302. doi: 10.1080/2162402X.2017.1299302. eCollection 2017.
1115 The atypical MAPK ERK3 potently suppresses melanoma cell growth and invasiveness.J Cell Physiol. 2019 Aug;234(8):13220-13232. doi: 10.1002/jcp.27994. Epub 2018 Dec 19.
1116 Psychological characteristics of early-stage melanoma patients: a cross-sectional study on 204 patients.Melanoma Res. 2017 Jun;27(3):277-280. doi: 10.1097/CMR.0000000000000348.
1117 Myoglobin does not predict local toxicity in isolated limb perfusion.Int J Hyperthermia. 2017 Sep;33(6):679-683. doi: 10.1080/02656736.2017.1309082. Epub 2017 Apr 10.
1118 A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.Oncogene. 2017 Jan 26;36(4):446-457. doi: 10.1038/onc.2016.219. Epub 2016 Jul 4.
1119 MED27 promotes melanoma growth by targeting AKT/MAPK and NF-B/iNOS signaling pathways.Cancer Lett. 2016 Apr 1;373(1):77-87. doi: 10.1016/j.canlet.2016.01.005. Epub 2016 Jan 18.
1120 Multiple endocrine neoplasia type 1 associated with a new germline Men1 mutation in a family with atypical tumor phenotype.Hormones (Athens). 2016 Jan-Mar;15(1):113-7. doi: 10.14310/horm.2002.1626.
1121 The importance of melanoma inhibitory activity gene family in the tumor progression of oral cancer.Pathol Int. 2018 May;68(5):278-286. doi: 10.1111/pin.12672. Epub 2018 Apr 14.
1122 A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.Oncogene. 2006 Nov 9;25(53):7059-69. doi: 10.1038/sj.onc.1209688. Epub 2006 May 22.
1123 MMP7 sensitivity of mutant ECM proteins: An indicator of melanoma survival rates and T-cell infiltration.Clin Biochem. 2019 Jan;63:85-91. doi: 10.1016/j.clinbiochem.2018.11.004. Epub 2018 Nov 8.
1124 C-Terminal Binding Protein 1 Modulates Cellular Redox via Feedback Regulation of MPC1 and MPC2 in Melanoma Cells.Med Sci Monit. 2018 Oct 25;24:7614-7624. doi: 10.12659/MSM.912735.
1125 Differential chemokine receptor expression and usage by pre-cDC1 and pre-cDC2.Immunol Cell Biol. 2018 Nov;96(10):1131-1139. doi: 10.1111/imcb.12186. Epub 2018 Jul 20.
1126 Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11.
1127 Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF- signaling.J Clin Invest. 2017 Apr 3;127(4):1321-1337. doi: 10.1172/JCI89281. Epub 2017 Mar 13.
1128 MSX1-Induced Neural Crest-Like Reprogramming Promotes MelanomaProgression.J Invest Dermatol. 2018 Jan;138(1):141-149. doi: 10.1016/j.jid.2017.05.038. Epub 2017 Sep 18.
1129 Exploring the potential of mucin 13 (MUC13) as a biomarker for carcinomas and other diseases.Clin Chem Lab Med. 2018 Oct 25;56(11):1945-1953. doi: 10.1515/cclm-2018-0139.
1130 Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis.Sci Rep. 2018 Jul 11;8(1):10449. doi: 10.1038/s41598-018-28717-y.
1131 Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.Neoplasia. 2013 Jul;15(7):826-39. doi: 10.1593/neo.13320.
1132 Myoferlin silencing inhibits VEGFR2-mediated proliferation of metastatic clear cell renal cell carcinoma.Sci Rep. 2019 Sep 2;9(1):12656. doi: 10.1038/s41598-019-48968-7.
1133 MYSM1/2A-DUB is an epigenetic regulator in human melanoma and contributes to tumor cell growth.Oncotarget. 2017 Jun 27;8(40):67287-67299. doi: 10.18632/oncotarget.18617. eCollection 2017 Sep 15.
1134 DNA hypermethylation is associated with invasive phenotype of malignant melanoma.Exp Dermatol. 2020 Jan;29(1):39-50. doi: 10.1111/exd.14047. Epub 2019 Nov 14.
1135 Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells.J Biol Chem. 2016 Aug 5;291(32):16630-43. doi: 10.1074/jbc.M115.708834. Epub 2016 Jun 10.
1136 NFAT5 promotes invivo development of murine melanoma metastasis.Biochem Biophys Res Commun. 2018 Nov 2;505(3):748-754. doi: 10.1016/j.bbrc.2018.09.171. Epub 2018 Oct 5.
1137 Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1.Br J Cancer. 2018 Dec;119(12):1538-1551. doi: 10.1038/s41416-018-0265-9. Epub 2018 Nov 2.
1138 Lymphoscintigraphy mapping of truncal malignant melanoma: A study of 212 patients at the Christie NHS Foundation Trust.J Plast Reconstr Aesthet Surg. 2017 Jan;70(1):37-39. doi: 10.1016/j.bjps.2016.08.017. Epub 2016 Sep 10.
1139 Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages.Int J Oral Sci. 2018 Aug 6;10(3):23. doi: 10.1038/s41368-018-0024-z.
1140 Cationic folate-mediated liposomal delivery of bis-arylidene oxindole induces efficient melanoma tumor regression.Biomater Sci. 2017 Aug 22;5(9):1898-1909. doi: 10.1039/c7bm00405b.
1141 Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.Oncogene. 2017 Jun 29;36(26):3789-3795. doi: 10.1038/onc.2016.511. Epub 2017 Feb 13.
1142 NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1 and p27(Kip1) expression in malignant melanoma and other human tumors.Mol Carcinog. 2017 Dec;56(12):2643-2662. doi: 10.1002/mc.22708. Epub 2017 Aug 30.
1143 The emerging role of NPNT in tissue injury repair and bone homeostasis.J Cell Physiol. 2018 Mar;233(3):1887-1894. doi: 10.1002/jcp.26013. Epub 2017 Jun 16.
1144 The shed ectodomain of Nr-CAM stimulates cell proliferation and motility, and confers cell transformation.Cancer Res. 2005 Dec 15;65(24):11605-12. doi: 10.1158/0008-5472.CAN-05-2647.
1145 NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs.Oxid Med Cell Longev. 2019 Sep 4;2019:2647068. doi: 10.1155/2019/2647068. eCollection 2019.
1146 Systemic therapy in non-conventional cancers of the larynx.Oral Oncol. 2018 Jul;82:61-68. doi: 10.1016/j.oraloncology.2018.05.005. Epub 2018 May 26.
1147 The effect of dielectrophoresis on living cells: crossover frequencies and deregulation in gene expression.Analyst. 2019 Jun 21;144(12):3853-3860. doi: 10.1039/c9an00320g. Epub 2019 May 17.
1148 OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.Cancer Res. 2005 Aug 15;65(16):7151-8. doi: 10.1158/0008-5472.CAN-05-1400.
1149 A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity.Cell Death Dis. 2015 Feb 12;6(2):e1634. doi: 10.1038/cddis.2015.17.
1150 Immune Cell-Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting and Drug Delivery.Small. 2017 Mar;13(10):10.1002/smll.201603121. doi: 10.1002/smll.201603121. Epub 2016 Dec 27.
1151 Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells.Cancers (Basel). 2019 Jan 16;11(1):102. doi: 10.3390/cancers11010102.
1152 Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma.Oncogene. 2017 Jun 22;36(25):3609-3617. doi: 10.1038/onc.2016.520. Epub 2017 Feb 6.
1153 MiR-370 functions as oncogene in melanoma by direct targeting pyruvate dehydrogenase B.Biomed Pharmacother. 2017 Jun;90:278-286. doi: 10.1016/j.biopha.2017.03.068. Epub 2017 Mar 30.
1154 Blocking podoplanin suppresses growth and pulmonary metastasis of human malignant melanoma.BMC Cancer. 2019 Jun 17;19(1):599. doi: 10.1186/s12885-019-5808-9.
1155 Declination of long noncoding RNA paternally expressed gene 10 inhibits A375 cells proliferation, migration, and invasion via mediating microRNA-33a.J Cell Biochem. 2019 Dec;120(12):19868-19877. doi: 10.1002/jcb.29292. Epub 2019 Jul 18.
1156 PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4.
1157 PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation.Oncogene. 2018 Apr;37(17):2225-2236. doi: 10.1038/s41388-017-0061-7. Epub 2018 Feb 2.
1158 Ensemble Modeling Approach Targeting Heterogeneous RNA-Seq data: Application to Melanoma Pseudogenes.Sci Rep. 2017 Dec 11;7(1):17344. doi: 10.1038/s41598-017-17337-7.
1159 Clinicopathological features and pituitary homeobox 1 gene expression in the progression and prognosis of cutaneous malignant melanoma.Kaohsiung J Med Sci. 2016 Oct;32(10):494-500. doi: 10.1016/j.kjms.2016.08.001. Epub 2016 Aug 27.
1160 An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin.Angew Chem Int Ed Engl. 2017 Jul 3;56(28):8267-8271. doi: 10.1002/anie.201702242. Epub 2017 May 26.
1161 Adipophilin expression in cutaneous malignant melanoma.J Cutan Pathol. 2017 Mar;44(3):228-236. doi: 10.1111/cup.12868. Epub 2016 Dec 22.
1162 p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib.Eur J Cancer. 2016 Mar;55:98-110. doi: 10.1016/j.ejca.2015.12.002. Epub 2016 Jan 17.
1163 Identification of genes potentially regulated by human polynucleotide phosphorylase (hPNPase old-35) using melanoma as a model.PLoS One. 2013 Oct 15;8(10):e76284. doi: 10.1371/journal.pone.0076284. eCollection 2013.
1164 Tumor Lysate-Loaded Lipid Hybrid Nanovaccine Collaborated with an Immune Checkpoint Antagonist for Combination Immunotherapy.Adv Healthc Mater. 2019 Jan;8(1):e1800837. doi: 10.1002/adhm.201800837. Epub 2018 Dec 3.
1165 FBXW7 regulates a mitochondrial transcription program by modulating MITF.Pigment Cell Melanoma Res. 2018 Sep;31(5):636-640. doi: 10.1111/pcmr.12704. Epub 2018 Apr 29.
1166 CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.Oncotarget. 2016 Nov 29;7(48):78242-78254. doi: 10.18632/oncotarget.12919.
1167 CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma.Oncotarget. 2018 Jul 27;9(58):31264-31277. doi: 10.18632/oncotarget.25805. eCollection 2018 Jul 27.
1168 In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma.Oncotarget. 2017 May 11;8(42):71817-71832. doi: 10.18632/oncotarget.17823. eCollection 2017 Sep 22.
1169 P-REX1 amplification promotes progression of cutaneous melanoma via the PAK1/P38/MMP-2 pathway.Cancer Lett. 2017 Oct 28;407:66-75. doi: 10.1016/j.canlet.2017.08.001. Epub 2017 Aug 10.
1170 REG accelerates melanoma formation by regulating Wnt/-catenin signalling pathway.Exp Dermatol. 2017 Nov;26(11):1118-1124. doi: 10.1111/exd.13394. Epub 2017 Aug 30.
1171 Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-B signaling pathway.Oncogene. 2019 Jul;38(30):5873-5889. doi: 10.1038/s41388-019-0848-9. Epub 2019 Jun 28.
1172 A Multikinase and DNA-PK Inhibitor Combination Immunomodulates Melanomas, Suppresses Tumor Progression, and Enhances Immunotherapies.Cancer Immunol Res. 2017 Sep;5(9):790-803. doi: 10.1158/2326-6066.CIR-17-0009. Epub 2017 Aug 3.
1173 Downregulation of pyrroline-5-carboxylate reductase-2 induces the autophagy of melanoma cells via AMPK/mTOR pathway.Tumour Biol. 2016 May;37(5):6485-91. doi: 10.1007/s13277-015-3927-8. Epub 2015 Dec 3.
1174 A Targeted Quantitative Proteomic Approach Assesses the Reprogramming of Small GTPases during Melanoma Metastasis.Cancer Res. 2018 Sep 15;78(18):5431-5445. doi: 10.1158/0008-5472.CAN-17-3811. Epub 2018 Aug 2.
1175 AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells.Cancers (Basel). 2019 Sep 3;11(9):1299. doi: 10.3390/cancers11091299.
1176 The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells.Oncogenesis. 2017 Jan 23;6(1):e291. doi: 10.1038/oncsis.2016.88.
1177 RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export.J Invest Dermatol. 2016 Jan;136(1):264-74. doi: 10.1038/JID.2015.401.
1178 Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.Oncotarget. 2012 Sep;3(9):1011-25. doi: 10.18632/oncotarget.622.
1179 Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis.Front Oncol. 2019 Nov 15;9:1253. doi: 10.3389/fonc.2019.01253. eCollection 2019.
1180 GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.Cell Rep. 2018 Feb 27;22(9):2455-2468. doi: 10.1016/j.celrep.2018.01.081.
1181 RASSF10 promoter hypermethylation is frequent in malignant melanoma of the skin but uncommon in nevus cell nevi.J Invest Dermatol. 2012 Mar;132(3 Pt 1):687-94. doi: 10.1038/jid.2011.380. Epub 2011 Nov 24.
1182 Epigenetic regulation of REG1A and chemosensitivity of cutaneous melanoma.Epigenetics. 2013 Oct;8(10):1043-52. doi: 10.4161/epi.25810. Epub 2013 Jul 31.
1183 Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment.Cell Mol Life Sci. 2012 Apr;69(7):1167-78. doi: 10.1007/s00018-011-0862-8. Epub 2011 Dec 1.
1184 Palmitoylation-dependent activation of MC1R prevents melanomagenesis.Nature. 2017 Sep 21;549(7672):399-403. doi: 10.1038/nature23887. Epub 2017 Sep 6.
1185 Nuclear envelope-distributed CD147 interacts with and inhibits the transcriptional function of RING1 and promotes melanoma cell motility.PLoS One. 2017 Aug 23;12(8):e0183689. doi: 10.1371/journal.pone.0183689. eCollection 2017.
1186 Macrophage inhibitory cytokine-1 regulates melanoma vascular development.Am J Pathol. 2010 Jun;176(6):2948-57. doi: 10.2353/ajpath.2010.090963. Epub 2010 Apr 29.
1187 Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-B Pathway in Melanoma.Clin Cancer Res. 2017 Aug 15;23(16):4831-4842. doi: 10.1158/1078-0432.CCR-17-0146. Epub 2017 Apr 7.
1188 Degradation of AMPK-1 sensitizes BRAF inhibitor-resistant melanoma cells to arginine deprivation.Mol Oncol. 2017 Dec;11(12):1806-1825. doi: 10.1002/1878-0261.12151. Epub 2017 Nov 16.
1189 The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types.Oncotarget. 2017 Feb 28;8(9):14462-14478. doi: 10.18632/oncotarget.14895.
1190 Palladium based nanoparticles for the treatment of advanced melanoma.Sci Rep. 2019 Mar 1;9(1):3255. doi: 10.1038/s41598-019-40258-6.
1191 Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma.Acta Pharmacol Sin. 2019 Feb;40(2):268-278. doi: 10.1038/s41401-018-0020-z. Epub 2018 May 18.
1192 Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation.Oncotarget. 2016 Apr 26;7(17):23885-96. doi: 10.18632/oncotarget.8127.
1193 A one-pot laccase-catalysed synthesis of coumestan derivatives and their anticancer activity.Bioorg Med Chem. 2017 Feb 1;25(3):1172-1182. doi: 10.1016/j.bmc.2016.12.025. Epub 2016 Dec 21.
1194 A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants.Int J Cancer. 2016 Nov 1;139(9):2012-20. doi: 10.1002/ijc.30245. Epub 2016 Jul 23.
1195 Prevalence and Correlates of Skin Cancer Screening Among Indoor Tanners and Nontanners.JAMA Dermatol. 2018 May 1;154(5):554-560. doi: 10.1001/jamadermatol.2018.0163.
1196 Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma.Nat Commun. 2016 Jul 18;7:12048. doi: 10.1038/ncomms12048.
1197 Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression.EBioMedicine. 2018 Nov;37:47-55. doi: 10.1016/j.ebiom.2018.10.002. Epub 2018 Oct 6.
1198 DSS1 promoter hypomethylation and overexpression predict poor prognosis in melanoma and squamous cell carcinoma patients.Hum Pathol. 2017 Feb;60:137-146. doi: 10.1016/j.humpath.2016.10.018. Epub 2016 Nov 4.
1199 Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb.J Exp Clin Cancer Res. 2018 Nov 19;37(1):278. doi: 10.1186/s13046-018-0933-x.
1200 MicroRNA-199a-5p inhibits tumor proliferation in melanoma by mediating HIF-1.Mol Med Rep. 2016 Jun;13(6):5241-7. doi: 10.3892/mmr.2016.5202. Epub 2016 Apr 28.
1201 Melanotic Translocation Renal Cell Carcinoma With a Novel ARID1B-TFE3 Gene Fusion.Am J Surg Pathol. 2017 Nov;41(11):1576-1580. doi: 10.1097/PAS.0000000000000927.
1202 sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.Nature. 2016 Apr 14;532(7598):250-4. doi: 10.1038/nature17392. Epub 2016 Apr 4.
1203 The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma.Oncotarget. 2016 Nov 29;7(48):78473-78486. doi: 10.18632/oncotarget.12954.
1204 Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.Cancer Lett. 2019 May 1;449:145-162. doi: 10.1016/j.canlet.2019.02.012. Epub 2019 Feb 14.
1205 Activation of CD8?T Cell Responses after Melanoma Antigen Targeting to CD169?Antigen Presenting Cells in Mice and Humans.Cancers (Basel). 2019 Feb 5;11(2):183. doi: 10.3390/cancers11020183.
1206 Gene expression and promoter methylation of angiogenic and lymphangiogenic factors as prognostic markers in melanoma.Mol Oncol. 2019 Jun;13(6):1433-1449. doi: 10.1002/1878-0261.12501. Epub 2019 May 25.
1207 Efficient TGF-/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.Mol Cancer. 2011 Jan 6;10(1):2. doi: 10.1186/1476-4598-10-2.
1208 Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1296-305. doi: 10.1073/pnas.1513801113. Epub 2016 Feb 16.
1209 Copper Chelation Inhibits BRAF(V600E)-Driven Melanomagenesis and Counters Resistance to BRAF(V600E) and MEK1/2 Inhibitors.Cancer Res. 2017 Nov 15;77(22):6240-6252. doi: 10.1158/0008-5472.CAN-16-1190. Epub 2017 Oct 6.
1210 Correlation of Tumor Burden in Sentinel Lymph Nodes with Tumor Burden in Nonsentinel Lymph Nodes and Survival in Cutaneous Melanoma.Clin Cancer Res. 2019 Dec 15;25(24):7585-7593. doi: 10.1158/1078-0432.CCR-19-1194. Epub 2019 Sep 30.
1211 SLURP-1 is mutated in Mal de Meleda, a potential molecular signature for melanoma and a putative squamous lineage tumor suppressor gene.Int J Dermatol. 2018 Feb;57(2):162-170. doi: 10.1111/ijd.13850. Epub 2017 Dec 12.
1212 MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.PLoS One. 2013;8(1):e54110. doi: 10.1371/journal.pone.0054110. Epub 2013 Jan 17.
1213 High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.Cell Rep. 2017 Oct 17;21(3):773-783. doi: 10.1016/j.celrep.2017.09.085.
1214 Outcomes of postoperative stereotactic radiosurgery to the resection cavity versus stereotactic radiosurgery alone for melanoma brain metastases.J Neurooncol. 2017 May;132(3):455-462. doi: 10.1007/s11060-017-2394-z. Epub 2017 Mar 4.
1215 Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.Stem Cells. 2016 Apr;34(4):832-46. doi: 10.1002/stem.2284. Epub 2016 Jan 19.
1216 IFN-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016.
1217 The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma.Front Oncol. 2019 Jan 4;8:584. doi: 10.3389/fonc.2018.00584. eCollection 2018.
1218 Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-nave and vemurafenib-resistant melanomas.Oncotarget. 2018 Dec 11;9(97):36945-36965. doi: 10.18632/oncotarget.26421. eCollection 2018 Dec 11.
1219 Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma.Science. 2018 Nov 30;362(6418):1055-1060. doi: 10.1126/science.aau6509. Epub 2018 Nov 1.
1220 The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region.Cell Rep. 2016 May 31;15(9):2025-37. doi: 10.1016/j.celrep.2016.04.018. Epub 2016 May 19.
1221 Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma.J Clin Invest. 2018 Jan 2;128(1):294-308. doi: 10.1172/JCI92513. Epub 2017 Dec 4.
1222 Signal Sequence Receptor 2 is required for survival of human melanoma cells as part of an unfolded protein response to endoplasmic reticulum stress.Mutagenesis. 2016 Sep;31(5):573-82. doi: 10.1093/mutage/gew023. Epub 2016 May 14.
1223 Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma.Nat Med. 2016 Sep;22(9):1056-61. doi: 10.1038/nm.4155. Epub 2016 Aug 8.
1224 STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.J Biol Chem. 2017 Nov 24;292(47):19392-19399. doi: 10.1074/jbc.M117.802884. Epub 2017 Oct 6.
1225 Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner.Oncol Lett. 2018 Jul;16(1):1291-1297. doi: 10.3892/ol.2018.8741. Epub 2018 May 18.
1226 Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis.Cell. 2019 Feb 21;176(5):1113-1127.e16. doi: 10.1016/j.cell.2019.01.002. Epub 2019 Jan 31.
1227 MAPK and Hippo signaling pathways crosstalk via the RAF-1/MST-2 interaction in malignant melanoma.Oncol Rep. 2017 Aug;38(2):1199-1205. doi: 10.3892/or.2017.5774. Epub 2017 Jun 30.
1228 Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma.Oncotarget. 2016 Dec 20;7(51):84486-84495. doi: 10.18632/oncotarget.12996.
1229 Precise control of apoptosis via gold nanostars for dose dependent photothermal therapy of melanoma.J Mater Chem B. 2019 Nov 28;7(44):6934-6944. doi: 10.1039/c9tb01956a. Epub 2019 Nov 1.
1230 Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types.Clin Epigenetics. 2019 Aug 5;11(1):114. doi: 10.1186/s13148-019-0710-5.
1231 Characterization of the typical multidrug resistance profile in human uveal melanoma cell lines and in mouse liver metastasis derivatives.Melanoma Res. 2005 Aug;15(4):257-66. doi: 10.1097/00008390-200508000-00005.
1232 Solid-in-Oil Peptide Nanocarriers for Transcutaneous Cancer Vaccine Delivery against Melanoma.Mol Pharm. 2018 Mar 5;15(3):955-961. doi: 10.1021/acs.molpharmaceut.7b00894. Epub 2018 Feb 15.
1233 Controlled Secretion of the Anticancer Protein MDA-7 from Engineered Mesenchymal Stem Cells.Biol Pharm Bull. 2017;40(1):113-117. doi: 10.1248/bpb.b16-00658.
1234 Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival.Int J Cancer. 2015 Aug 1;137(3):638-45. doi: 10.1002/ijc.29429. Epub 2015 Jan 28.
1235 Transcription factor LSF (TFCP2) inhibits melanoma growth.Oncotarget. 2016 Jan 19;7(3):2379-90. doi: 10.18632/oncotarget.6230.
1236 MITF has a central role in regulating starvation-induced autophagy in melanoma.Sci Rep. 2019 Jan 31;9(1):1055. doi: 10.1038/s41598-018-37522-6.
1237 Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.Genes Chromosomes Cancer. 2012 May;51(5):452-61. doi: 10.1002/gcc.21932. Epub 2012 Jan 17.
1238 Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells.Am J Pathol. 2012 Apr;180(4):1663-74. doi: 10.1016/j.ajpath.2011.12.035. Epub 2012 Feb 9.
1239 Downregulation of reversion-inducing cysteine-rich protein with Kazal motifs in malignant melanoma: inverse correlation with membrane-type 1-matrix metalloproteinase and tissue inhibitor of metalloproteinase 2.Melanoma Res. 2014 Feb;24(1):32-9. doi: 10.1097/CMR.0000000000000039.
1240 In silico analysis of transmembrane protein 31 (TMEM31) antigen to design novel multiepitope peptide and DNA cancer vaccines against melanoma.Mol Immunol. 2019 Aug;112:93-102. doi: 10.1016/j.molimm.2019.04.030. Epub 2019 May 9.
1241 Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach.Sci Rep. 2017 Dec 11;7(1):17314. doi: 10.1038/s41598-017-17330-0.
1242 Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression.Methods Mol Biol. 2017;1513:83-100. doi: 10.1007/978-1-4939-6539-7_7.
1243 Design and Production of Newcastle Disease Virus for Intratumoral Immunomodulation.Methods Mol Biol. 2020;2058:133-154. doi: 10.1007/978-1-4939-9794-7_9.
1244 miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.Oncotarget. 2015 Feb 20;6(5):2966-80. doi: 10.18632/oncotarget.3070.
1245 Metformin reduces TRIB3 expression and restores autophagy flux: an alternative antitumor action.Autophagy. 2018;14(7):1278-1279. doi: 10.1080/15548627.2018.1460022. Epub 2018 Jul 20.
1246 Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.J Cancer Res Clin Oncol. 2019 Sep;145(9):2241-2250. doi: 10.1007/s00432-019-02981-5. Epub 2019 Jul 24.
1247 Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells.Sci Rep. 2016 Jul 28;6:30405. doi: 10.1038/srep30405.
1248 AP2 controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression.Oncogene. 2016 Jun 9;35(23):3016-26. doi: 10.1038/onc.2015.357. Epub 2015 Oct 5.
1249 BRAF Inhibitors Amplify the Proapoptotic Activity of MEK Inhibitors by Inducing ER Stress in NRAS-Mutant Melanoma.Clin Cancer Res. 2017 Oct 15;23(20):6203-6214. doi: 10.1158/1078-0432.CCR-17-0098. Epub 2017 Jul 19.
1250 miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells.Int J Oncol. 2013 Apr;42(4):1443-51. doi: 10.3892/ijo.2013.1823. Epub 2013 Feb 12.
1251 Prognostic Relevance of CCDC88C (Daple) Transcripts in the Peripheral Blood of Patients with Cutaneous Melanoma.Sci Rep. 2018 Dec 21;8(1):18036. doi: 10.1038/s41598-018-36173-x.
1252 The long non-coding RNA CRNDE competed endogenously with miR-205 to promote proliferation and metastasis of melanoma cells by targeting CCL18.Cell Cycle. 2018;17(18):2296-2308. doi: 10.1080/15384101.2018.1526602. Epub 2018 Oct 9.
1253 Targeting Rac and Cdc42 GTPases in Cancer.Cancer Res. 2018 Jun 15;78(12):3101-3111. doi: 10.1158/0008-5472.CAN-18-0619. Epub 2018 Jun 1.
1254 Loss of T-cadherin (CDH-13) regulates AKT signaling and desensitizes cells to apoptosis in melanoma.Mol Carcinog. 2014 Aug;53(8):635-47. doi: 10.1002/mc.22018. Epub 2013 Apr 26.
1255 Review of the medical literature and assessment of current utilization patterns regarding the use of two common fluorescence in situ hybridization assays in the diagnosis of dermatofibrosarcoma protuberans and clear cell sarcoma.J Cutan Pathol. 2018 Dec;45(12):905-913. doi: 10.1111/cup.13345. Epub 2018 Sep 27.
1256 Matricellular TSP-1 as a target of interest for impeding melanoma spreading: towards a therapeutic use for TAX2 peptide.Clin Exp Metastasis. 2016 Oct;33(7):637-49. doi: 10.1007/s10585-016-9803-0. Epub 2016 Jun 27.
1257 The Structure in Solution of Fibronectin Type III Domain 14 Reveals Its Synergistic Heparin Binding Site.Biochemistry. 2018 Oct 23;57(42):6045-6049. doi: 10.1021/acs.biochem.8b00771. Epub 2018 Oct 11.
1258 Loss of neural crest-associated gene FOXD1 impairs melanoma invasion and migration via RAC1B downregulation.Int J Cancer. 2018 Dec 1;143(11):2962-2972. doi: 10.1002/ijc.31799. Epub 2018 Sep 29.
1259 Down-regulation of GADD45A enhances chemosensitivity in melanoma.Sci Rep. 2018 Mar 7;8(1):4111. doi: 10.1038/s41598-018-22484-6.
1260 Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.Nat Commun. 2018 Aug 22;9(1):3368. doi: 10.1038/s41467-018-05795-0.
1261 Differential UBE2C and HOXA1 expression in melanocytic nevi and melanoma.J Cutan Pathol. 2017 Oct;44(10):843-850. doi: 10.1111/cup.12997. Epub 2017 Jul 21.
1262 Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis.Oncotarget. 2015 Sep 8;6(26):23026-35. doi: 10.18632/oncotarget.4854.
1263 Inhibition of tumor-associated v3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo.Angiogenesis. 2015 Jan;18(1):31-46. doi: 10.1007/s10456-014-9445-2. Epub 2014 Sep 24.
1264 Role of inhibitor of growth 4 in the suppression of human melanoma cells through the Fas/FasL-mediated apoptosis pathway.Int J Mol Med. 2018 Feb;41(2):1055-1061. doi: 10.3892/ijmm.2017.3274. Epub 2017 Nov 20.
1265 Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses.Oncotarget. 2017 Jul 18;8(29):47440-47453. doi: 10.18632/oncotarget.17663.
1266 Effects of microRNA-708 on Epithelial-Mesenchymal Transition, Cell Proliferation and Apoptosis in Melanoma Cells by Targeting LEF1 through the Wnt Signaling Pathway.Pathol Oncol Res. 2019 Jan;25(1):377-389. doi: 10.1007/s12253-017-0334-z. Epub 2017 Nov 14.
1267 Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide.Sci Rep. 2017 Aug 9;7(1):7700. doi: 10.1038/s41598-017-07043-9.
1268 A targeted therapy for melanoma by graphene oxide composite with microRNA carrier.Drug Des Devel Ther. 2018 Sep 21;12:3095-3106. doi: 10.2147/DDDT.S160088. eCollection 2018.
1269 NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt/-catenin signaling pathway.Braz J Med Biol Res. 2018 Nov 23;52(1):e7952. doi: 10.1590/1414-431X20187952.
1270 Trial watch: Peptide-based vaccines in anticancer therapy.Oncoimmunology. 2018 Sep 6;7(12):e1511506. doi: 10.1080/2162402X.2018.1511506. eCollection 2018.
1271 WIPI1, BAG1, and PEX3 Autophagy-Related Genes Are Relevant Melanoma Markers.Oxid Med Cell Longev. 2018 Dec 2;2018:1471682. doi: 10.1155/2018/1471682. eCollection 2018.
1272 Mechanism of miR-137 regulating migration and invasion of melanoma cells by targeting PIK3R3 gene.J Cell Biochem. 2019 May;120(5):8393-8400. doi: 10.1002/jcb.28124. Epub 2018 Nov 28.
1273 Panduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathway.Phytomedicine. 2018 Mar 15;42:144-151. doi: 10.1016/j.phymed.2018.03.027. Epub 2018 Mar 15.
1274 67-kDa laminin receptor-dependent protein phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance.J Biol Chem. 2014 Nov 21;289(47):32671-81. doi: 10.1074/jbc.M114.604983. Epub 2014 Oct 7.
1275 Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma.Hum Mutat. 2014 Nov;35(11):1301-10. doi: 10.1002/humu.22630. Epub 2014 Sep 10.
1276 Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma.Cancer Manag Res. 2018 Nov 27;10:6399-6407. doi: 10.2147/CMAR.S166711. eCollection 2018.
1277 RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.Int J Cancer. 2019 Jun 15;144(12):3070-3085. doi: 10.1002/ijc.32064. Epub 2019 Jan 3.
1278 High RNA-binding Motif Protein 3 Expression Is Associated with Improved Clinical Outcomes in Invasive Breast Cancer.J Breast Cancer. 2018 Sep;21(3):288-296. doi: 10.4048/jbc.2018.21.e34. Epub 2018 Aug 28.
1279 Tip110/SART3 regulates IL-8 expression and predicts the clinical outcomes in melanoma.Mol Cancer. 2018 Aug 17;17(1):124. doi: 10.1186/s12943-018-0868-z.
1280 SFRP5 inhibits the migration and invasion of melanoma cells through Wnt signaling pathway.Onco Targets Ther. 2018 Dec 6;11:8761-8772. doi: 10.2147/OTT.S181146. eCollection 2018.
1281 MicroRNA-605 functions as a tumor suppressor by targeting INPP4B in melanoma.Oncol Rep. 2017 Aug;38(2):1276-1286. doi: 10.3892/or.2017.5740. Epub 2017 Jun 22.
1282 The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration.Cell Death Dis. 2018 Sep 19;9(10):939. doi: 10.1038/s41419-018-1011-1.
1283 Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway.Oncotarget. 2014 Aug 15;5(15):6387-403. doi: 10.18632/oncotarget.2201.
1284 miR?0a?p inhibits the proliferation, migration and invasion of melanoma cells by targeting SOX4.Mol Med Rep. 2018 Aug;18(2):2492-2498. doi: 10.3892/mmr.2018.9166. Epub 2018 Jun 14.
1285 STAM-binding protein regulates melanoma metastasis through SLUG stabilization.Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):484-488. doi: 10.1016/j.bbrc.2018.11.068. Epub 2018 Nov 16.
1286 Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads.Nat Commun. 2019 Feb 20;10(1):877. doi: 10.1038/s41467-019-08691-3.
1287 TBX2 expression is regulated by PAX3 in the melanocyte lineage.Pigment Cell Melanoma Res. 2013 Jan;26(1):67-77. doi: 10.1111/pcmr.12029. Epub 2012 Nov 21.
1288 Mitochondrial transcription factor A (TFAM) shapes metabolic and invasion gene signatures in melanoma.Sci Rep. 2018 Sep 21;8(1):14190. doi: 10.1038/s41598-018-31170-6.
1289 MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor.PLoS One. 2015 Jan 14;10(1):e0115919. doi: 10.1371/journal.pone.0115919. eCollection 2015.
1290 Constitutional promoter methylation and risk of familial melanoma.Epigenetics. 2014 May;9(5):685-92. doi: 10.4161/epi.28151. Epub 2014 Feb 13.
1291 Association of TNFRSF10D DNA-methylation with the survival of melanoma patients.Int J Mol Sci. 2014 Jul 7;15(7):11984-95. doi: 10.3390/ijms150711984.
1292 A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice.Melanoma Res. 2012 Jun;22(3):225-35. doi: 10.1097/CMR.0b013e32835312fd.
1293 Running for time: circadian rhythms and melanoma.Tumour Biol. 2014 Sep;35(9):8359-68. doi: 10.1007/s13277-014-1904-2. Epub 2014 Apr 14.
1294 Apoptosis-associated tyrosine kinase 1 inhibits growth and migration and promotes apoptosis in melanoma.Lab Invest. 2014 Apr;94(4):430-8. doi: 10.1038/labinvest.2014.13. Epub 2014 Mar 3.
1295 AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.Cancer Res. 2015 Sep 1;75(17):3492-504. doi: 10.1158/0008-5472.CAN-15-0088. Epub 2015 Jul 2.
1296 Molecular profiling of ADAM12 and ADAM17 genes in human malignant melanoma.Pathol Oncol Res. 2013 Oct;19(4):755-62. doi: 10.1007/s12253-013-9639-8. Epub 2013 May 6.
1297 AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma.Cell Death Dis. 2013 Nov 7;4(11):e914. doi: 10.1038/cddis.2013.441.
1298 Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.PLoS One. 2016 Aug 12;11(8):e0161165. doi: 10.1371/journal.pone.0161165. eCollection 2016.
1299 Endothelial monocyte activating polypeptide II induces endothelial cell apoptosis and may inhibit tumor angiogenesis.Microvasc Res. 2000 Jul;60(1):70-80. doi: 10.1006/mvre.2000.2249.
1300 AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma.Oncotarget. 2016 Sep 20;7(38):60872-60884. doi: 10.18632/oncotarget.11506.
1301 Disruption of Proline Synthesis in Melanoma Inhibits Protein Production Mediated by the GCN2 Pathway.Mol Cancer Res. 2015 Oct;13(10):1408-20. doi: 10.1158/1541-7786.MCR-15-0048. Epub 2015 Jun 16.
1302 A pilot study of genetic variants in dopamine regulators with indoor tanning and melanoma.Exp Dermatol. 2013 Sep;22(9):576-81. doi: 10.1111/exd.12200.
1303 TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types.Cancer Cell. 2012 Feb 14;21(2):212-26. doi: 10.1016/j.ccr.2012.01.004.
1304 Melanoma's high C>T mutation rate: is deamination playing a role?.Exp Dermatol. 2014 Aug;23(8):551-2. doi: 10.1111/exd.12436. Epub 2014 Aug 1.
1305 Functional and cancer genomics of ASXL family members.Br J Cancer. 2013 Jul 23;109(2):299-306. doi: 10.1038/bjc.2013.281. Epub 2013 Jun 4.
1306 Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.Cell Signal. 2014 Feb;26(2):287-94. doi: 10.1016/j.cellsig.2013.11.008. Epub 2013 Nov 12.
1307 Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo.Blood. 2010 Apr 15;115(15):3025-32. doi: 10.1182/blood-2009-11-253641. Epub 2010 Feb 3.
1308 Wnt/-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274.
1309 MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD).J Invest Dermatol. 2013 May;133(5):1286-93. doi: 10.1038/jid.2012.400. Epub 2012 Nov 29.
1310 BAP31, a promising target for the immunotherapy of malignant melanomas.J Exp Clin Cancer Res. 2015 Apr 18;34(1):36. doi: 10.1186/s13046-015-0153-6.
1311 Downregulation of cylindromatosis gene, CYLD, confers a growth advantage on malignant melanoma cells while negatively regulating their migration activity.Int J Oncol. 2012 Jul;41(1):53-60. doi: 10.3892/ijo.2012.1424. Epub 2012 Apr 2.
1312 Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink.Carbohydr Polym. 2013 Jan 2;91(1):403-9. doi: 10.1016/j.carbpol.2012.08.050. Epub 2012 Aug 22.
1313 A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells.Cancer Lett. 2013 Oct 1;339(1):93-101. doi: 10.1016/j.canlet.2013.07.019. Epub 2013 Jul 20.
1314 Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.Oncol Rep. 2013 Dec;30(6):2887-96. doi: 10.3892/or.2013.2791. Epub 2013 Oct 10.
1315 The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.Oncotarget. 2015 Oct 6;6(30):29111-28. doi: 10.18632/oncotarget.5059.
1316 Downregulation of CCN3 expression as a potential mechanism for melanoma progression.Oncogene. 2008 Apr 17;27(18):2552-60. doi: 10.1038/sj.onc.1210896. Epub 2007 Oct 29.
1317 MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D.Pigment Cell Melanoma Res. 2014 Mar;27(2):275-86. doi: 10.1111/pcmr.12200. Epub 2014 Jan 17.
1318 DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma.Cancer Immunol Immunother. 2015 Apr;64(4):409-18. doi: 10.1007/s00262-014-1648-2. Epub 2014 Dec 31.
1319 Cadherin-7 interacts with melanoma inhibitory activity protein and negatively modulates melanoma cell migration.Cancer Sci. 2009 Feb;100(2):261-8. doi: 10.1111/j.1349-7006.2008.01048.x.
1320 Death-signal-induced relocalization of cyclin-dependent kinase 11 to mitochondria.Biochem J. 2005 Nov 15;392(Pt 1):65-73. doi: 10.1042/BJ20050195.
1321 MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations.Am J Hum Genet. 2001 Oct;69(4):765-73. doi: 10.1086/323412. Epub 2001 Aug 8.
1322 Downregulation of CIC does not associate with overexpression of ETV1 or MAP kinase pathway activation in gastrointestinal stromal tumors.Cancer Invest. 2014 Aug;32(7):363-7. doi: 10.3109/07357907.2014.919304. Epub 2014 Jun 4.
1323 Discovering biological connections between experimental conditions based on common patterns of differential gene expression.BMC Bioinformatics. 2011 Sep 27;12:381. doi: 10.1186/1471-2105-12-381.
1324 Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.Eur J Cancer. 2014 Dec;50(18):3168-77. doi: 10.1016/j.ejca.2014.09.017. Epub 2014 Oct 31.
1325 Assessing a single SNP located at TERT/CLPTM1L multi-cancer risk region as a genetic modifier for risk of pancreatic cancer and melanoma in Dutch CDKN2A mutation carriers.Fam Cancer. 2019 Oct;18(4):439-444. doi: 10.1007/s10689-019-00137-5.
1326 Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival.Am J Pathol. 2013 Mar;182(3):678-87. doi: 10.1016/j.ajpath.2012.11.036. Epub 2013 Jan 26.
1327 Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma.Oncotarget. 2015 Jan 20;6(2):1115-27. doi: 10.18632/oncotarget.2747.
1328 TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion.Br J Cancer. 2013 Jul 23;109(2):422-32. doi: 10.1038/bjc.2013.242. Epub 2013 May 14.
1329 A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy.Cancer Gene Ther. 2012 Apr;19(4):247-54. doi: 10.1038/cgt.2011.84. Epub 2011 Dec 23.
1330 Diagnostic SOX10 gene signatures in salivary adenoid cystic and breast basal-like carcinomas.Br J Cancer. 2013 Jul 23;109(2):444-51. doi: 10.1038/bjc.2013.326. Epub 2013 Jun 25.
1331 Inherited variation at MC1R and ASIP and association with melanoma-specific survival.Int J Cancer. 2015 Jun 1;136(11):2659-67. doi: 10.1002/ijc.29317. Epub 2014 Nov 26.
1332 Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver.Cancer Biol Ther. 2013 Jul;14(7):614-24. doi: 10.4161/cbt.24594. Epub 2013 May 10.
1333 Ras-induced melanoma transformation is associated with the proteasomal degradation of the transcriptional repressor ICER.Mol Carcinog. 2013 Sep;52(9):692-704. doi: 10.1002/mc.21908. Epub 2012 Apr 4.
1334 CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis.Int J Mol Med. 2014 Jun;33(6):1484-90. doi: 10.3892/ijmm.2014.1721. Epub 2014 Apr 2.
1335 Alpha-catulin contributes to drug-resistance of melanoma by activating NF-B and AP-1.PLoS One. 2015 Mar 20;10(3):e0119402. doi: 10.1371/journal.pone.0119402. eCollection 2015.
1336 Nucleus accumbens-associated 1 contributes to cortactin deacetylation and augments the migration of melanoma cells.J Invest Dermatol. 2011 Aug;131(8):1710-9. doi: 10.1038/jid.2011.110. Epub 2011 May 12.
1337 TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6021-6. doi: 10.1073/pnas.1303607110. Epub 2013 Mar 25.
1338 Transcriptional regulation of ASK/Dbf4 in cutaneous melanoma is dependent on E2F1.Exp Dermatol. 2008 Dec;17(12):986-91. doi: 10.1111/j.1600-0625.2008.00730.x. Epub 2008 May 21.
1339 The helicase HAGE prevents interferon--induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.Cell Death Dis. 2014 Feb 13;5(2):e1061. doi: 10.1038/cddis.2014.29.
1340 Nucleoside Analog Activity in Malignant Melanoma Cell Lines.Nucleosides Nucleotides Nucleic Acids. 2015;34(9):639-49. doi: 10.1080/15257770.2015.1047029.
1341 Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression.Oncogene. 2013 Feb 14;32(7):837-48. doi: 10.1038/onc.2012.115. Epub 2012 Apr 2.
1342 The metastasis gene NEDD9 product acts through integrin 3 and Src to promote mesenchymal motility and inhibit amoeboid motility.J Cell Sci. 2012 Apr 1;125(Pt 7):1814-26. doi: 10.1242/jcs.101444. Epub 2012 Feb 10.
1343 Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4+ Th1 Cells.PLoS One. 2015 May 20;10(5):e0124094. doi: 10.1371/journal.pone.0124094. eCollection 2015.
1344 Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk.Carcinogenesis. 2013 Apr;34(4):885-92. doi: 10.1093/carcin/bgs407. Epub 2013 Jan 4.
1345 Human Melanoma cells over-express extracellular matrix 1 (ECM1) which is regulated by TFAP2C.PLoS One. 2013 Sep 2;8(9):e73953. doi: 10.1371/journal.pone.0073953. eCollection 2013.
1346 Metastatic melanoma of unknown primary resembles the genotype of cutaneous melanomas.Ann Oncol. 2014 Jan;25(1):246-50. doi: 10.1093/annonc/mdt411. Epub 2013 Nov 24.
1347 Synergistic effects of eIF4A and MEK inhibitors on proliferation of NRAS-mutant melanoma cell lines.Cell Cycle. 2016 Sep 16;15(18):2405-9. doi: 10.1080/15384101.2016.1208862. Epub 2016 Aug 11.
1348 Cytokine-induced killer cells engineered with exogenous T-cell receptors directed against melanoma antigens: enhanced efficacy of effector cells endowed with a double mechanism of tumor recognition.Hum Gene Ther. 2015 Apr;26(4):220-31. doi: 10.1089/hum.2014.112. Epub 2015 Apr 13.
1349 Abnormal hypermethylation and clinicopathological significance of FBLN1 gene in cutaneous melanoma.Tumour Biol. 2014 Jan;35(1):123-7. doi: 10.1007/s13277-013-1015-5. Epub 2013 Aug 2.
1350 DNA repair variants, indoor tanning, and risk of melanoma.Pigment Cell Melanoma Res. 2013 Sep;26(5):677-84. doi: 10.1111/pcmr.12117. Epub 2013 Jun 3.
1351 Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.Cell Cycle. 2012 Sep 1;11(17):3250-9. doi: 10.4161/cc.21611. Epub 2012 Aug 16.
1352 Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.Cancer Res. 1999 Jul 1;59(13):3157-65.
1353 Functional proteomics, human genetics and cancer biology of GIPC family members.Exp Mol Med. 2013 Jun 7;45(6):e26. doi: 10.1038/emm.2013.49.
1354 G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation.Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):419-26. doi: 10.1161/ATVBAHA.113.302689. Epub 2013 Nov 21.
1355 G13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.Int J Cancer. 2015 Sep 15;137(6):1503-8. doi: 10.1002/ijc.29506. Epub 2015 Mar 16.
1356 Promoter CpG island hypermethylation in dysplastic nevus and melanoma: CLDN11 as an epigenetic biomarker for malignancy.J Invest Dermatol. 2014 Dec;134(12):2957-2966. doi: 10.1038/jid.2014.270. Epub 2014 Jul 7.
1357 Glycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line.PLoS One. 2014 Jun 26;9(6):e100896. doi: 10.1371/journal.pone.0100896. eCollection 2014.
1358 Melanoma cells control HA synthesis in peritumoral fibroblasts via PDGF-AA and PDGF-CC: impact on melanoma cell proliferation.J Invest Dermatol. 2012 Feb;132(2):385-93. doi: 10.1038/jid.2011.325. Epub 2011 Oct 13.
1359 Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion.Exp Cell Res. 2015 Sep 10;337(1):1-15. doi: 10.1016/j.yexcr.2015.07.026. Epub 2015 Jul 26.
1360 Expression and release of HLA-E by melanoma cells and melanocytes: potential impact on the response of cytotoxic effector cells.J Immunol. 2006 Sep 1;177(5):3100-7. doi: 10.4049/jimmunol.177.5.3100.
1361 Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.Mol Cell. 2015 Aug 6;59(3):345-358. doi: 10.1016/j.molcel.2015.05.037. Epub 2015 Jul 2.
1362 Oncogenic HoxB7 requires TALE cofactors and is inactivated by a dominant-negative Pbx1 mutant in a cell-specific manner.Cancer Lett. 2008 Aug 8;266(2):144-55. doi: 10.1016/j.canlet.2008.02.042. Epub 2008 Apr 2.
1363 Combination of adenoviruses expressing melanoma differentiation-associated gene-7 and chemotherapeutic agents produces enhanced cytotoxicity on esophageal carcinoma.Cancer Gene Ther. 2014 Jan;21(1):31-7. doi: 10.1038/cgt.2013.79. Epub 2014 Jan 17.
1364 IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive Tcells.Eur J Immunol. 2016 Jul;46(7):1770-82. doi: 10.1002/eji.201546061. Epub 2016 May 6.
1365 Involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma.PLoS One. 2014 Apr 17;9(4):e95522. doi: 10.1371/journal.pone.0095522. eCollection 2014.
1366 Nuclear ING2 expression is reduced in human cutaneous melanomas.Br J Cancer. 2006 Jul 3;95(1):80-6. doi: 10.1038/sj.bjc.6603205. Epub 2006 Jun 6.
1367 MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project.Int J Cancer. 2015 Feb 1;136(3):618-31. doi: 10.1002/ijc.29018. Epub 2014 Jun 18.
1368 Role of Tip60 in human melanoma cell migration, metastasis, and patient survival.J Invest Dermatol. 2012 Nov;132(11):2632-41. doi: 10.1038/jid.2012.193. Epub 2012 Jun 7.
1369 Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling.PLoS One. 2013 May 21;8(5):e63597. doi: 10.1371/journal.pone.0063597. Print 2013.
1370 MicroRNA-203 regulates melanosome transport and tyrosinase expression in melanoma cells by targeting kinesin superfamily protein 5b.J Invest Dermatol. 2014 Feb;134(2):461-469. doi: 10.1038/jid.2013.310. Epub 2013 Jul 22.
1371 Expression and functions of galectin-7 in human and murine melanomas.PLoS One. 2013 May 3;8(5):e63307. doi: 10.1371/journal.pone.0063307. Print 2013.
1372 Loss of Hugl-1 expression associates with lymph node metastasis in endometrial cancer.Oncol Res. 2007;16(9):431-5. doi: 10.3727/000000007783980855.
1373 Knockdown of lecithin retinol acyltransferase increases all-trans retinoic acid levels and restores retinoid sensitivity in malignant melanoma cells.Exp Dermatol. 2014 Nov;23(11):832-7. doi: 10.1111/exd.12548. Epub 2014 Oct 10.
1374 NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.Cancer Lett. 2007 Jun 8;250(2):268-75. doi: 10.1016/j.canlet.2006.10.020. Epub 2006 Nov 30.
1375 The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells.Carcinogenesis. 2012 Oct;33(10):1871-81. doi: 10.1093/carcin/bgs236. Epub 2012 Jul 12.
1376 A knockdown of Maml1 that results in melanoma cell senescence promotes an innate and adaptive immune response.Cancer Immunol Immunother. 2013 Jan;62(1):183-90. doi: 10.1007/s00262-012-1318-1. Epub 2012 Aug 5.
1377 Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1101-10. doi: 10.1158/1055-9965.EPI-14-1380-T. Epub 2015 May 7.
1378 MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cells.J Biol Chem. 2015 Feb 6;290(6):3333-48. doi: 10.1074/jbc.M114.606913. Epub 2014 Dec 10.
1379 Minichromosome maintenance protein expression in benign nevi, dysplastic nevi, melanoma, and cutaneous melanoma metastases.J Am Acad Dermatol. 2008 May;58(5):750-4. doi: 10.1016/j.jaad.2007.12.026. Epub 2008 Feb 4.
1380 Expression of integrins 31 and 51 and GlcNAc 1,6 glycan branching influences metastatic melanoma cell migration on fibronectin.Eur J Cell Biol. 2013 Dec;92(12):355-62. doi: 10.1016/j.ejcb.2013.10.007. Epub 2013 Nov 1.
1381 Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.Oncotarget. 2015 Feb 20;6(5):2779-93. doi: 10.18632/oncotarget.2995.
1382 RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca2+/MICU1 dependent mitochondrial signaling.Oncotarget. 2015 Oct 6;6(30):29614-25. doi: 10.18632/oncotarget.4868.
1383 Absence of RIPK3 predicts necroptosis resistance in malignant melanoma.Cell Death Dis. 2015 Sep 10;6(9):e1884. doi: 10.1038/cddis.2015.240.
1384 Keratinocyte-derived laminin-332 protein promotes melanin synthesis via regulation of tyrosine uptake.J Biol Chem. 2014 Aug 1;289(31):21751-9. doi: 10.1074/jbc.M113.541177. Epub 2014 Jun 20.
1385 MTSS1 is a metastasis driver in a subset of human melanomas.Nat Commun. 2014 Mar 17;5:3465. doi: 10.1038/ncomms4465.
1386 MX 2 is a novel regulator of cell cycle in melanoma cells.Pigment Cell Melanoma Res. 2020 May;33(3):446-457. doi: 10.1111/pcmr.12837. Epub 2019 Nov 13.
1387 Knockdown of myosin VI by lentivirus-mediated short hairpin RNA suppresses proliferation of melanoma.Mol Med Rep. 2015 Nov;12(5):6801-6. doi: 10.3892/mmr.2015.4261. Epub 2015 Aug 28.
1388 HOXC11-SRC-1 regulation of S100beta in cutaneous melanoma: new targets for the kinase inhibitor dasatinib.Br J Cancer. 2011 Jun 28;105(1):118-23. doi: 10.1038/bjc.2011.193. Epub 2011 Jun 7.
1389 Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.Cancer Res. 2014 Jul 1;74(13):3429-40. doi: 10.1158/0008-5472.CAN-13-3017. Epub 2014 Apr 29.
1390 Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus.Cancer Sci. 2011 Jan;102(1):122-9. doi: 10.1111/j.1349-7006.2010.01775.x. Epub 2010 Nov 12.
1391 CD147 interacts with NDUFS6 in regulating mitochondrial complex I activity and the mitochondrial apoptotic pathway in human malignant melanoma cells.Curr Mol Med. 2014;14(10):1252-64. doi: 10.2174/1566524014666141202144601.
1392 Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.Int J Exp Pathol. 2014 Feb;95(1):24-8. doi: 10.1111/iep.12051. Epub 2013 Oct 31.
1393 Targeting NEU Protein in Melanoma Cells with Non-Thermal Atmospheric Pressure Plasma and Gold Nanoparticles.J Biomed Nanotechnol. 2015 May;11(5):900-5. doi: 10.1166/jbn.2015.1999.
1394 Amplified lipid rafts of malignant cells constitute a target for inhibition of aberrantly active NFAT and melanoma tumor growth by the aminobisphosphonate zoledronic acid.Carcinogenesis. 2014 Nov;35(11):2555-66. doi: 10.1093/carcin/bgu178. Epub 2014 Aug 20.
1395 Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.Nat Genet. 2015 Oct;47(10):1194-9. doi: 10.1038/ng.3382. Epub 2015 Sep 7.
1396 Four cardiac hormones cause cell death of melanoma cells and inhibit their DNA synthesis.Am J Med Sci. 2007 Nov;334(5):342-9. doi: 10.1097/MAJ.0b013e318068b627.
1397 Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling.BMC Cancer. 2013 May 7;13:227. doi: 10.1186/1471-2407-13-227.
1398 Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion.Oncotarget. 2015 Jun 30;6(18):15953-65. doi: 10.18632/oncotarget.3643.
1399 Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.PLoS One. 2012;7(5):e36054. doi: 10.1371/journal.pone.0036054. Epub 2012 May 2.
1400 The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway.Int J Cancer. 2013 Aug 15;133(4):879-92. doi: 10.1002/ijc.28097. Epub 2013 Mar 13.
1401 Protein Kinase CK2 Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2 Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma.J Biol Chem. 2016 Aug 19;291(34):17804-15. doi: 10.1074/jbc.M115.712885. Epub 2016 May 17.
1402 PHF19 and Akt control the switch between proliferative and invasive states in melanoma.Cell Cycle. 2012 Apr 15;11(8):1634-45. doi: 10.4161/cc.20095. Epub 2012 Apr 15.
1403 TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.
1404 Impaired PIASy-Tip60 signaling weakens activation of p53 in melanoma.Melanoma Res. 2013 Jun;23(3):213-7. doi: 10.1097/CMR.0b013e328361056d.
1405 Harnessing autophagy to overcome mitogen-activated protein kinase kinase inhibitor-induced resistance in metastatic melanoma. Br J Dermatol. 2019 Feb;180(2):346-356. doi: 10.1111/bjd.17333. Epub 2018 Nov 25.
1406 Cloning of the human phospholipase A2 activating protein (hPLAP) gene on the chromosome 9p21 melanoma deleted region.Gene. 1999 Oct 18;239(1):155-61. doi: 10.1016/s0378-1119(99)00354-6.
1407 Oncogenic suppression of PHLPP1 in human melanoma.Oncogene. 2014 Sep 25;33(39):4756-66. doi: 10.1038/onc.2013.420. Epub 2013 Oct 14.
1408 Plexin D1 is ubiquitously expressed on tumor vessels and tumor cells in solid malignancies.BMC Cancer. 2009 Aug 25;9:297. doi: 10.1186/1471-2407-9-297.
1409 POLE mutations in families predisposed to cutaneous melanoma.Fam Cancer. 2015 Dec;14(4):621-8. doi: 10.1007/s10689-015-9826-8.
1410 hShroom1 links a membrane bound protein to the actin cytoskeleton.Cell Mol Life Sci. 2009 Feb;66(4):681-96. doi: 10.1007/s00018-009-8645-1.
1411 Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.J Immunol. 2013 Jun 15;190(12):6034-42. doi: 10.4049/jimmunol.1202830. Epub 2013 May 20.
1412 RacGAP1-driven focal adhesion formation promotes melanoma transendothelial migration through mediating adherens junction disassembly.Biochem Biophys Res Commun. 2015 Mar 27;459(1):1-9. doi: 10.1016/j.bbrc.2014.11.088. Epub 2014 Dec 2.
1413 Germline RAD51B truncating mutation in a family with cutaneous melanoma.Fam Cancer. 2015 Jun;14(2):337-40. doi: 10.1007/s10689-015-9781-4.
1414 Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.Pigment Cell Melanoma Res. 2014 Jul;27(4):640-52. doi: 10.1111/pcmr.12248. Epub 2014 May 14.
1415 RASSF6 exhibits promoter hypermethylation in metastatic melanoma and inhibits invasion in melanoma cells.Epigenetics. 2014 Nov;9(11):1496-503. doi: 10.4161/15592294.2014.983361.
1416 RASSF8 regulates progression of cutaneous melanoma through nuclear factor-b.Oncotarget. 2015 Oct 6;6(30):30165-77. doi: 10.18632/oncotarget.5030.
1417 Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
1418 Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes.J Immunol. 2014 Nov 15;193(10):4803-13. doi: 10.4049/jimmunol.1400800. Epub 2014 Oct 13.
1419 REST negatively and ISGF3 positively regulate the human STAT1 gene in melanoma.Mol Cancer Ther. 2013 Jul;12(7):1288-98. doi: 10.1158/1535-7163.MCT-12-0923. Epub 2013 Apr 18.
1420 Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.Mol Cell. 2016 May 19;62(4):507-19. doi: 10.1016/j.molcel.2016.04.014.
1421 JWA inhibits melanoma angiogenesis by suppressing ILK signaling and is an independent prognostic biomarker for melanoma.Carcinogenesis. 2013 Dec;34(12):2778-88. doi: 10.1093/carcin/bgt318. Epub 2013 Sep 24.
1422 A switch in RND3-RHOA signaling is critical for melanoma cell invasion following mutant-BRAF inhibition.Mol Cancer. 2011 Sep 14;10:114. doi: 10.1186/1476-4598-10-114.
1423 Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.Cell Rep. 2015 Jun 9;11(9):1458-73. doi: 10.1016/j.celrep.2015.04.049. Epub 2015 May 28.
1424 Ribonuclease inhibitor up-regulation inhibits the growth and induces apoptosis in murine melanoma cells through repression of angiogenin and ILK/PI3K/AKT signaling pathway.Biochimie. 2014 Aug;103:89-100. doi: 10.1016/j.biochi.2014.04.007. Epub 2014 Apr 24.
1425 p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells.J Dermatol Sci. 2012 Oct;68(1):19-24. doi: 10.1016/j.jdermsci.2012.07.005. Epub 2012 Aug 2.
1426 YY1 regulates melanoma tumorigenesis through a miR-9~RYBP axis.J Exp Clin Cancer Res. 2015 Jun 24;34(1):66. doi: 10.1186/s13046-015-0177-y.
1427 Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance.Br J Cancer. 2014 May 13;110(10):2489-95. doi: 10.1038/bjc.2014.169. Epub 2014 Apr 10.
1428 Regulation of S100A2 expression by TGF--induced MEK/ERK signalling and its role in cell migration/invasion.Biochem J. 2012 Oct 1;447(1):81-91. doi: 10.1042/BJ20120014.
1429 SAGE and antibody array analysis of melanoma-infiltrated lymph nodes: identification of Ubc9 as an important molecule in advanced-stage melanomas.Oncogene. 2007 Jun 21;26(29):4216-25. doi: 10.1038/sj.onc.1210216. Epub 2007 Feb 12.
1430 Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation.Epigenetics. 2012 Aug;7(8):903-13. doi: 10.4161/epi.21107. Epub 2012 Jun 22.
1431 SBF-1, a synthetic steroidal glycoside, inhibits melanoma growth and metastasis through blocking interaction between PDK1 and AKT3.Biochem Pharmacol. 2012 Jul 15;84(2):172-81. doi: 10.1016/j.bcp.2012.04.006. Epub 2012 Apr 13.
1432 Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells.PLoS One. 2014 Feb 18;9(2):e89491. doi: 10.1371/journal.pone.0089491. eCollection 2014.
1433 Histone deacetylase inhibitor sensitizes apoptosis-resistant melanomas to cytotoxic human T lymphocytes through regulation of TRAIL/DR5 pathway.J Immunol. 2014 Apr 15;192(8):3981-9. doi: 10.4049/jimmunol.1302532. Epub 2014 Mar 17.
1434 Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling.Oncotarget. 2015 Oct 20;6(32):33091-105. doi: 10.18632/oncotarget.5173.
1435 Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy.Cancer Res. 2013 Apr 1;73(7):2247-58. doi: 10.1158/0008-5472.CAN-12-2501. Epub 2013 Jan 28.
1436 Increased expression of sex determining region Y-box 11 (SOX11) in cutaneous malignant melanoma.J Int Med Res. 2013 Aug;41(4):1221-7. doi: 10.1177/0300060513476592. Epub 2013 Jul 18.
1437 SPANX-B and SPANX-C (Xq27 region) gene dosage analysis in Sicilian patients with melanoma.Melanoma Res. 2008 Aug;18(4):295-9. doi: 10.1097/CMR.0b013e32830aaa90.
1438 Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening.Pigment Cell Melanoma Res. 2013 Jan;26(1):97-112. doi: 10.1111/pcmr.12031. Epub 2012 Nov 6.
1439 Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential.J Invest Dermatol. 2015 Jul;135(7):1849-1862. doi: 10.1038/jid.2015.95. Epub 2015 Mar 10.
1440 Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry.Pigment Cell Melanoma Res. 2014 May;27(3):442-53. doi: 10.1111/pcmr.12222. Epub 2014 Mar 7.
1441 STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice.Cancer Immunol Immunother. 2015 Aug;64(8):1057-66. doi: 10.1007/s00262-015-1713-5. Epub 2015 May 19.
1442 PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. Nature. 2014 Oct 9;514(7521):247-51.
1443 MicroRNA-143 targets Syndecan-1 to repress cell growth in melanoma.PLoS One. 2014 Apr 10;9(4):e94855. doi: 10.1371/journal.pone.0094855. eCollection 2014.
1444 MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma.Aging (Albany NY). 2016 May;8(5):933-44. doi: 10.18632/aging.100951.
1445 Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase.J Dermatol Sci. 2006 Sep;43(3):189-200. doi: 10.1016/j.jdermsci.2006.05.007. Epub 2006 Jun 27.
1446 Prognostic relevance of the expressions of CAV1 and TES genes on 7q31 in melanoma.Front Biosci (Elite Ed). 2012 Jan 1;4(5):1802-12. doi: 10.2741/501.
1447 Interaction of human Thy-1 (CD 90) with the integrin alphavbeta3 (CD51/CD61): an important mechanism mediating melanoma cell adhesion to activated endothelium.Oncogene. 2005 Jul 7;24(29):4710-20. doi: 10.1038/sj.onc.1208559.
1448 TRIB2 as a biomarker for diagnosis and progression of melanoma.Carcinogenesis. 2015 Apr;36(4):469-77. doi: 10.1093/carcin/bgv002. Epub 2015 Jan 13.
1449 The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells.PLoS One. 2008 Mar 5;3(3):e0001737. doi: 10.1371/journal.pone.0001737.
1450 Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.J Natl Cancer Inst. 2014 Dec 13;107(2):dju408. doi: 10.1093/jnci/dju408. Print 2015 Feb.
1451 Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.Mol Cancer Res. 2010 Nov;8(11):1513-25. doi: 10.1158/1541-7786.MCR-10-0262. Epub 2010 Oct 13.
1452 A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.PLoS One. 2011 Apr 29;6(4):e19271. doi: 10.1371/journal.pone.0019271.
1453 Vulvar malignant melanoma associated with human papillomavirus DNA: report of two cases and review of literature.Am J Dermatopathol. 2002 Jun;24(3):230-40. doi: 10.1097/00000372-200206000-00008.
1454 Analysis of Mucosal Melanoma Whole-Genome Landscapes Reveals Clinically Relevant Genomic Aberrations.Clin Cancer Res. 2019 Jun 15;25(12):3548-3560. doi: 10.1158/1078-0432.CCR-18-3442. Epub 2019 Feb 19.
1455 Differential modulatory effects of GSK-3 and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma.Mol Cancer. 2011 Sep 19;10:115. doi: 10.1186/1476-4598-10-115.
1456 ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output.Cancers (Basel). 2019 Dec 6;11(12):1963. doi: 10.3390/cancers11121963.
1457 Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.Cancer Res. 2011 Apr 1;71(7):2561-71. doi: 10.1158/0008-5472.CAN-10-2958. Epub 2011 Feb 22.
1458 Redirecting mouse T hybridoma against human breast and ovarian carcinomas: in vivo activity against HER-2/neu expressing cancer cells.Br J Cancer. 2003 Apr 22;88(8):1292-300. doi: 10.1038/sj.bjc.6600888.
1459 Knockdown of aristaless-like homeobox1 inhibits epithelial-mesenchymal transition through Wnt/-catenin signaling pathway in melanoma cells.Biochem Biophys Res Commun. 2019 Mar 26;511(1):105-110. doi: 10.1016/j.bbrc.2019.02.050. Epub 2019 Feb 14.
1460 Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas.Br J Dermatol. 2020 Jan;182(1):156-165. doi: 10.1111/bjd.18086. Epub 2019 Jun 19.
1461 Expression and function of the AMF receptor by human melanoma in experimental and clinical systems.Clin Exp Metastasis. 2002;19(3):225-32. doi: 10.1023/a:1015595708241.
1462 AMPH-1 is a tumor suppressor of lung cancer by inhibiting Ras-Raf-MEK-ERK signal pathway.Lasers Med Sci. 2019 Apr;34(3):473-478. doi: 10.1007/s10103-018-2616-4. Epub 2018 Aug 24.
1463 Recombinant angioarrestin secreted from mouse melanoma cells inhibits growth of primary tumours.Acta Biochim Pol. 2005;52(4):875-9. Epub 2005 Jun 6.
1464 Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.Genes Dev. 2019 Dec 1;33(23-24):1641-1656. doi: 10.1101/gad.329417.119. Epub 2019 Nov 14.
1465 Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression.Cancer Res. 1996 Sep 1;56(17):3855-8.
1466 Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.Hum Mol Genet. 2011 Dec 15;20(24):5012-23. doi: 10.1093/hmg/ddr415. Epub 2011 Sep 17.
1467 Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and growth of melanoma cells.J Biol Chem. 2011 May 27;286(21):18492-504. doi: 10.1074/jbc.M110.189811. Epub 2011 Mar 26.
1468 Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells.Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7200-4. doi: 10.1073/pnas.90.15.7200.
1469 Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity.Cancer Res. 2008 Oct 15;68(20):8221-30. doi: 10.1158/0008-5472.CAN-08-0561.
1470 Identification of ARHGEF17, DENND2D, FGFR3, and RB1 mutations in melanoma by inhibition of nonsense-mediated mRNA decay.Genes Chromosomes Cancer. 2008 Dec;47(12):1076-85. doi: 10.1002/gcc.20598.
1471 Coexpression of major histocompatibility complex class II with chemokines and nuclear NFkappaB p50 in melanoma: a rational for their association with poor prognosis.Melanoma Res. 2009 Aug;19(4):226-37. doi: 10.1097/CMR.0b013e32832e0bc3.
1472 ARLTS1 variants and melanoma risk.Int J Cancer. 2006 Oct 1;119(7):1736-7. doi: 10.1002/ijc.22008.
1473 Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma.Cancer Res. 2001 Nov 1;61(21):7900-7.
1474 Systems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma.Oncoimmunology. 2019 Sep 24;8(12):e1665978. doi: 10.1080/2162402X.2019.1665978. eCollection 2019.
1475 Arpc1b gene is a candidate prediction marker for choroidal malignant melanomas sensitive to radiotherapy.Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2300-4. doi: 10.1167/iovs.05-0810.
1476 DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma.Clin Cancer Res. 2005 May 15;11(10):3609-13. doi: 10.1158/1078-0432.CCR-04-1941.
1477 Scleral Thinning Documented by Ultrasound Biomicroscopy after Plaque Therapy for Anterior Ciliary Melanoma.Semin Ophthalmol. 2018;33(4):571-575. doi: 10.1080/08820538.2017.1346131. Epub 2017 Jul 13.
1478 Arginine deiminase resistance in melanoma cells is associated with metabolic reprogramming, glucose dependence, and glutamine addiction.Mol Cancer Ther. 2013 Nov;12(11):2581-90. doi: 10.1158/1535-7163.MCT-13-0302. Epub 2013 Aug 26.
1479 miR-216b enhances the efficacy of vemurafenib by targeting Beclin-1, UVRAG and ATG5 in melanoma.Cell Signal. 2018 Jan;42:30-43. doi: 10.1016/j.cellsig.2017.09.024. Epub 2017 Oct 2.
1480 Elevated expression of the V-ATPase D2 subunit triggers increased energy metabolite levels in Kras(G12D) -driven cancer cells.J Cell Biochem. 2019 Jul;120(7):11690-11701. doi: 10.1002/jcb.28448. Epub 2019 Feb 11.
1481 Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma.Genes Chromosomes Cancer. 2008 Jul;47(7):614-24. doi: 10.1002/gcc.20567.
1482 Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice.Int J Cancer. 2003 Feb 20;103(5):606-15. doi: 10.1002/ijc.10881.
1483 Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction.Cancer Res. 2014 Jan 15;74(2):563-74. doi: 10.1158/0008-5472.CAN-13-1062. Epub 2013 Nov 26.
1484 Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts.FEBS Lett. 2003 Oct 23;553(3):250-6. doi: 10.1016/s0014-5793(03)01017-2.
1485 Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways.Clin Cancer Res. 2012 Jun 15;18(12):3316-27. doi: 10.1158/1078-0432.CCR-11-2232. Epub 2012 May 2.
1486 Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway.Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4583-4591. doi: 10.1073/pnas.1821889116. Epub 2019 Feb 19.
1487 Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent.Toxicol Appl Pharmacol. 2008 Aug 15;231(1):61-7. doi: 10.1016/j.taap.2008.03.020. Epub 2008 Apr 9.
1488 Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts.BMC Med Genet. 2019 May 3;20(1):69. doi: 10.1186/s12881-019-0808-9.
1489 Comparison of calmodulin gene expression in human neonatal melanocytes and metastatic melanoma cell lines.J Invest Dermatol. 1992 Dec;99(6):764-73. doi: 10.1111/1523-1747.ep12614725.
1490 Preventing Calpain Externalization by Reducing ABCA1 Activity with Probenecid Limits Melanoma Angiogenesis and Development.J Invest Dermatol. 2020 Feb;140(2):445-454. doi: 10.1016/j.jid.2019.06.148. Epub 2019 Aug 16.
1491 Laminin-421 produced by lymphatic endothelial cells induces chemotaxis for human melanoma cells.Pigment Cell Melanoma Res. 2009 Oct;22(5):601-10. doi: 10.1111/j.1755-148X.2009.00590.x. Epub 2009 Jun 5.
1492 Activation of CCR9/CCL25 in cutaneous melanoma mediates preferential metastasis to the small intestine.Clin Cancer Res. 2008 Feb 1;14(3):638-45. doi: 10.1158/1078-0432.CCR-07-2025.
1493 Homophilic interactions of Tetraspanin CD151 up-regulate motility and matrix metalloproteinase-9 expression of human melanoma cells through adhesion-dependent c-Jun activation signaling pathways.J Biol Chem. 2006 Aug 25;281(34):24279-92. doi: 10.1074/jbc.M601209200. Epub 2006 Jun 23.
1494 Increased cytoplasmatic expression of cancer immune surveillance receptor CD1d in anaplastic thyroid carcinomas.Cancer Med. 2019 Nov;8(16):7065-7073. doi: 10.1002/cam4.2573. Epub 2019 Sep 27.
1495 The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumor-infiltrating lymphocytes.Int J Cancer. 1994 May 15;57(4):612-9. doi: 10.1002/ijc.2910570428.
1496 Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression.PLoS One. 2007 Jul 4;2(7):e594. doi: 10.1371/journal.pone.0000594.
1497 CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1379-84. doi: 10.1073/pnas.1017228108. Epub 2011 Jan 10.
1498 CDK5RAP1 targeting NF-B signaling pathway in human malignant melanoma A375 cell apoptosis.Oncol Lett. 2018 Apr;15(4):4767-4774. doi: 10.3892/ol.2018.7920. Epub 2018 Feb 1.
1499 Germ-line deletion involving the INK4 locus in familial proneness to melanoma and nervous system tumors.Cancer Res. 1998 Jun 1;58(11):2298-303.
1500 Expression of APITD1 is not related to copy number changes of chromosomal region 1p36 or the prognosis of uveal melanoma.Invest Ophthalmol Vis Sci. 2007 Nov;48(11):4919-23. doi: 10.1167/iovs.07-0061.
1501 The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma.J Biol Chem. 2010 Aug 27;285(35):27487-27498. doi: 10.1074/jbc.M110.155382. Epub 2010 Jun 29.
1502 An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles.Cancer Cell. 2019 Jan 14;35(1):33-45.e6. doi: 10.1016/j.ccell.2018.12.001.
1503 Preliminary evidence for involvement of the tumour suppressor gene CHD5 in a family with cutaneous melanoma.Br J Dermatol. 2011 May;164(5):1010-6. doi: 10.1111/j.1365-2133.2011.10223.x.
1504 Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p.Mol Ther Nucleic Acids. 2019 Jun 7;16:63-72. doi: 10.1016/j.omtn.2019.02.007. Epub 2019 Feb 20.
1505 Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10.Cancer Res. 2009 Jun 15;69(12):5218-25. doi: 10.1158/0008-5472.CAN-09-0705. Epub 2009 May 26.
1506 Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma.Epigenetics. 2011 Mar;6(3):388-94. doi: 10.4161/epi.6.3.14056. Epub 2011 Mar 1.
1507 Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.Cancer Res. 2006 Jun 15;66(12):6080-6. doi: 10.1158/0008-5472.CAN-06-0157.
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1510 ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope.Eur J Immunol. 2020 Feb;50(2):270-283. doi: 10.1002/eji.201948116. Epub 2019 Nov 27.
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1512 Conditionally replication-competent adenoviral vectors with enhanced infectivity for use in gene therapy of melanoma.Hum Gene Ther. 2004 Jul;15(7):637-47. doi: 10.1089/1043034041361181.
1513 AIM1 and LINE-1 epigenetic aberrations in tumor and serum relate to melanoma progression and disease outcome.J Invest Dermatol. 2012 Jun;132(6):1689-97. doi: 10.1038/jid.2012.36. Epub 2012 Mar 8.
1514 Expression analysis of genes identified by molecular profiling of VGP melanomas and MGP melanoma-positive lymph nodes.Cancer Biol Ther. 2004 Jan;3(1):110-20. doi: 10.4161/cbt.3.1.662. Epub 2004 Jan 24.
1515 Contact of high-invasive, but not low-invasive, melanoma cells to native collagen I induces the release of mature cathepsin B.Int J Cancer. 2006 Jun 1;118(11):2735-43. doi: 10.1002/ijc.21700.
1516 cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.J Invest Dermatol. 2003 Jul;121(1):198-206. doi: 10.1046/j.1523-1747.2003.12318.x.
1517 Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.Int J Cancer. 2002 Aug 10;100(5):549-56. doi: 10.1002/ijc.10512.
1518 The transcription factor CUTL1 is associated with proliferation and prognosis in malignant melanoma.Melanoma Res. 2014 Jun;24(3):198-206. doi: 10.1097/CMR.0000000000000064.
1519 Isotypic neutralizing antibodies against mouse GCP-2/CXCL6 inhibit melanoma growth and metastasis.Cancer Lett. 2011 Mar 1;302(1):54-62. doi: 10.1016/j.canlet.2010.12.013. Epub 2011 Jan 13.
1520 CD4+ T-cell response to mitochondrial cytochrome B in human melanoma.Cancer Res. 2006 Jun 1;66(11):5919-26. doi: 10.1158/0008-5472.CAN-05-4574.
1521 Genome-wide screening identifies novel genes implicated in cellular sensitivity to BRAF(V600E) expression.Oncogene. 2020 Jan;39(4):723-738. doi: 10.1038/s41388-019-1022-0. Epub 2019 Sep 23.
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1524 DEPDC1B knockdown inhibits the development of malignant melanoma through suppressing cell proliferation and inducing cell apoptosis.Exp Cell Res. 2019 Jun 1;379(1):48-54. doi: 10.1016/j.yexcr.2019.03.021. Epub 2019 Mar 14.
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1527 MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells.Cancer Res. 2006 Aug 15;66(16):7939-47. doi: 10.1158/0008-5472.CAN-06-1888.
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1530 Characterization of several leukemia-associated antigens inducing humoral immune responses in acute and chronic myeloid leukemia.Int J Cancer. 2003 Aug 20;106(2):224-31. doi: 10.1002/ijc.11200.
1531 Antiproliferative activity of vanadium compounds: effects on the major malignant melanoma molecular pathways.Metallomics. 2019 Oct 16;11(10):1687-1699. doi: 10.1039/c9mt00174c.
1532 DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells.Curr Biol. 2008 Oct 14;18(19):1456-65. doi: 10.1016/j.cub.2008.08.053. Epub 2008 Oct 2.
1533 Silencing of diphthamide synthesis 3 (Dph3) reduces metastasis of murine melanoma.PLoS One. 2012;7(11):e49988. doi: 10.1371/journal.pone.0049988. Epub 2012 Nov 20.
1534 DRG2 supports the growth of primary tumors and metastases of melanoma by enhancing VEGF-A expression.FEBS J. 2020 May;287(10):2070-2086. doi: 10.1111/febs.15125. Epub 2019 Dec 1.
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1536 Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development.Oncogene. 2001 Dec 6;20(56):8125-35. doi: 10.1038/sj.onc.1205034.
1537 Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression.Mol Cancer Res. 2007 Aug;5(8):761-71. doi: 10.1158/1541-7786.MCR-07-0088.
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1548 FARP1 Facilitates Cell Proliferation Through Modulating MAPK Signaling Pathway in Cutaneous Melanoma.Am J Dermatopathol. 2019 Dec;41(12):908-913. doi: 10.1097/DAD.0000000000001426.
1549 Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis.PLoS One. 2015 Feb 13;10(2):e0118336. doi: 10.1371/journal.pone.0118336. eCollection 2015.
1550 Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1/VEGF pathway.Invest New Drugs. 2020 Feb;38(1):20-28. doi: 10.1007/s10637-019-00761-z. Epub 2019 Mar 18.
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1552 Identifying FL11 subtype by characterizing tumor immune microenvironment in prostate adenocarcinoma via Chou's 5-steps rule.Genomics. 2020 Mar;112(2):1500-1515. doi: 10.1016/j.ygeno.2019.08.021. Epub 2019 Aug 28.
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1557 Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma.PLoS One. 2011 Apr 8;6(4):e18369. doi: 10.1371/journal.pone.0018369.
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1559 Ferritin light chain down-modulation generates depigmentation in human metastatic melanoma cells by influencing tyrosinase maturation.J Cell Physiol. 2006 Mar;206(3):843-8. doi: 10.1002/jcp.20543.
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1568 GBP-5 splicing variants: New guanylate-binding proteins with tumor-associated expression and antigenicity.J Invest Dermatol. 2004 Jun;122(6):1510-7. doi: 10.1111/j.0022-202X.2004.22613.x.
1569 c-RET molecule in malignant melanoma from oncogenic RET-carrying transgenic mice and human cell lines.PLoS One. 2010 Apr 21;5(4):e10279. doi: 10.1371/journal.pone.0010279.
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1573 Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.Nat Commun. 2019 Apr 11;10(1):1689. doi: 10.1038/s41467-019-09397-2.
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1580 Association Between Activation of the Programmed Cell Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) Pathway and Pain in Patients with Cancer.Med Sci Monit. 2019 Feb 16;25:1275-1282. doi: 10.12659/MSM.912632.
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1582 Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells. World J Gastroenterol. 2005 Oct 7;11(37):5763-9. doi: 10.3748/wjg.v11.i37.5763.
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1586 Oxalomalate reduces tumor progression in melanoma via ROS-dependent proapoptotic and antiangiogenic effects.Biochimie. 2019 Mar;158:165-171. doi: 10.1016/j.biochi.2019.01.004. Epub 2019 Jan 9.
1587 Interferon-alpha induces reversible DNA demethylation of the interferon-induced transmembrane protein-3 core promoter in human melanoma cells.J Interferon Cytokine Res. 2011 Aug;31(8):601-8. doi: 10.1089/jir.2010.0134. Epub 2011 Mar 17.
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1589 Antiproliferative activity of IL-27 on melanoma.J Immunol. 2008 May 15;180(10):6527-35. doi: 10.4049/jimmunol.180.10.6527.
1590 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.Nature. 2010 Jul 1;466(7302):133-7. doi: 10.1038/nature09161.
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1595 Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression.Front Genet. 2018 Dec 18;9:675. doi: 10.3389/fgene.2018.00675. eCollection 2018.
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1597 Neo-DREAM study investigating Daromun for the treatment of clinical stage IIIB/C melanoma.Future Oncol. 2019 Nov;15(32):3665-3674. doi: 10.2217/fon-2019-0433. Epub 2019 Sep 20.
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1599 ARMS depletion facilitates UV irradiation induced apoptotic cell death in melanoma.Cancer Res. 2007 Dec 15;67(24):11547-56. doi: 10.1158/0008-5472.CAN-07-1930.
1600 KIF15 plays a role in promoting the tumorigenicity of melanoma.Exp Eye Res. 2019 Aug;185:107598. doi: 10.1016/j.exer.2019.02.014. Epub 2019 Feb 21.
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1604 MHC class I-independent recognition of NK-activating receptor KIR2DS4.J Immunol. 2004 Aug 1;173(3):1819-25. doi: 10.4049/jimmunol.173.3.1819.
1605 NEAT1/miR-23a-3p/KLF3: a novel regulatory axis in melanoma cancer progression.Cancer Cell Int. 2019 Aug 22;19:217. doi: 10.1186/s12935-019-0927-6. eCollection 2019.
1606 KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment.J Natl Cancer Inst. 2010 Aug 4;102(15):1131-47. doi: 10.1093/jnci/djq218. Epub 2010 Jul 21.
1607 KLF9-dependent ROS regulate melanoma progression in stage-specific manner.Oncogene. 2019 May;38(19):3585-3597. doi: 10.1038/s41388-019-0689-6. Epub 2019 Jan 21.
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1609 Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).Oncogene. 2003 Mar 6;22(9):1418-24. doi: 10.1038/sj.onc.1206272.
1610 Lichen planus: molecular pathway and clinical implications in oral disorders.J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):135-138.
1611 Cross-species application of cDNA microarrays to profile gene expression using UV-induced melanoma in Monodelphis domestica as the model system.Genomics. 2004 Apr;83(4):588-99. doi: 10.1016/j.ygeno.2003.10.007.
1612 Melanoma cells produce multiple laminin isoforms and strongly migrate on 5 laminin(s) via several integrin receptors.Exp Cell Res. 2011 May 1;317(8):1119-33. doi: 10.1016/j.yexcr.2010.12.019. Epub 2010 Dec 31.
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1621 A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12.J Immunol. 2000 Apr 15;164(8):4382-92. doi: 10.4049/jimmunol.164.8.4382.
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1645 Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library.Cancer Res. 2000 Jul 1;60(13):3584-91.
1646 Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.BMC Cancer. 2011 Oct 12;11:443. doi: 10.1186/1471-2407-11-443.
1647 Hypoxic Gene Signature of Primary and Metastatic Melanoma Cell Lines: Focusing on HIF-1 and NDRG-1.Balkan Med J. 2019 Dec 20;37(1):15-23. doi: 10.4274/balkanmedj.galenos.2019.2019.3.145. Epub 2019 Oct 9.
1648 Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.Cancer Sci. 2011 Dec;102(12):2139-49. doi: 10.1111/j.1349-7006.2011.02086.x. Epub 2011 Oct 17.
1649 Decreased expression of nemo-like kinase in melanoma is correlated with increased vascularity and metastasis.Melanoma Res. 2019 Aug;29(4):376-381. doi: 10.1097/CMR.0000000000000576.
1650 Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth.Int J Cancer. 2009 Aug 1;125(3):556-64. doi: 10.1002/ijc.24276.
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1652 Melanosome maturation proteins Oca2, Mitfa and Vps11 are differentially required for cisplatin resistance in zebrafish melanocytes.Exp Dermatol. 2019 Jul;28(7):795-800. doi: 10.1111/exd.13937. Epub 2019 May 15.
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1654 The role of the OVOL1-OVOL2 axis in normal and diseased human skin.J Dermatol Sci. 2018 Jun;90(3):227-231. doi: 10.1016/j.jdermsci.2018.02.005. Epub 2018 Feb 12.
1655 Pembrolizumab Plus Pegylated Interferon alfa-2b or Ipilimumab for Advanced Melanoma or Renal Cell Carcinoma: Dose-Finding Results from the Phase Ib KEYNOTE-029 Study.Clin Cancer Res. 2018 Apr 15;24(8):1805-1815. doi: 10.1158/1078-0432.CCR-17-3436. Epub 2018 Jan 22.
1656 RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.Carcinogenesis. 2008 Jun;29(6):1157-63. doi: 10.1093/carcin/bgn119. Epub 2008 May 29.
1657 PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.PLoS One. 2011;6(8):e22312. doi: 10.1371/journal.pone.0022312. Epub 2011 Aug 18.
1658 Ca2+ binding to EF hands 1 and 3 is essential for the interaction of apoptosis-linked gene-2 with Alix/AIP1 in ocular melanoma.Biochemistry. 2004 Sep 7;43(35):11175-86. doi: 10.1021/bi048848d.
1659 Role of ERp57 in the signaling and transcriptional activity of STAT3 in a melanoma cell line.Arch Biochem Biophys. 2010 Feb 15;494(2):178-83. doi: 10.1016/j.abb.2009.12.004. Epub 2009 Dec 6.
1660 Identification and characterization of a novel melanoma tumor suppressor gene on human chromosome 6q21.Clin Cancer Res. 2009 Feb 1;15(3):797-803. doi: 10.1158/1078-0432.CCR-08-1472.
1661 Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression.Nat Med. 2011 Jan;17(1):123-9. doi: 10.1038/nm.2269. Epub 2010 Dec 12.
1662 Expression of p53-induced apoptosis effector PERP in primary uveal melanomas: downregulation is associated with aggressive type.Exp Eye Res. 2006 Oct;83(4):911-9. doi: 10.1016/j.exer.2006.04.016. Epub 2006 Jun 19.
1663 Phase I/II trial of gene therapy with autologous tumor cells modified with tag7/PGRP-S gene in patients with disseminated solid tumors: miscellaneous tumors.Ann Oncol. 2005 Jan;16(1):162-8. doi: 10.1093/annonc/mdi028.
1664 Epigenetic regulation of the transcription factor Foxa2 directs differential elafin expression in melanocytes and melanoma cells.Biochem Biophys Res Commun. 2011 Apr 29;408(1):160-6. doi: 10.1016/j.bbrc.2011.04.001. Epub 2011 Apr 3.
1665 Humoral immune response against melanoma antigens induced by vaccination with cytokine gene-modified autologous tumor cells.Int J Cancer. 2004 Jan 10;108(2):307-13. doi: 10.1002/ijc.11537.
1666 A small-molecule inhibitor shows that pirin regulates migration of melanoma cells.Nat Chem Biol. 2010 Sep;6(9):667-73. doi: 10.1038/nchembio.423. Epub 2010 Aug 15.
1667 Coexpression network analysis identified that plakophilin 1 is associated with the metastasis in human melanoma.Biomed Pharmacother. 2019 Mar;111:1234-1242. doi: 10.1016/j.biopha.2018.12.135. Epub 2019 Jan 15.
1668 PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.Biochem Biophys Res Commun. 2019 Jan 8;508(2):646-653. doi: 10.1016/j.bbrc.2018.11.163. Epub 2018 Dec 4.
1669 Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.Mol Med Rep. 2020 Jan;21(1):420-428. doi: 10.3892/mmr.2019.10798. Epub 2019 Nov 6.
1670 Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi.Mod Pathol. 2017 Mar;30(3):350-356. doi: 10.1038/modpathol.2016.201. Epub 2016 Dec 9.
1671 The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion.Pigment Cell Melanoma Res. 2019 May;32(3):424-434. doi: 10.1111/pcmr.12760. Epub 2018 Dec 21.
1672 A distinct octamer-binding protein present in malignant melanoma cells.Nucleic Acids Res. 1988 Dec 9;16(23):11047-56. doi: 10.1093/nar/16.23.11047.
1673 BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.Genes Dev. 2019 Mar 1;33(5-6):310-332. doi: 10.1101/gad.314633.118. Epub 2019 Feb 25.
1674 GADD153 is an independent prognostic factor in melanoma: immunohistochemical and molecular genetic analysis.Histol Histopathol. 2002;17(3):805-11. doi: 10.14670/HH-17.805.
1675 Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms.Oncogene. 2000 Feb 24;19(9):1191-5. doi: 10.1038/sj.onc.1203389.
1676 Phosphorylation of eIF2 triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma.Sci Signal. 2015 Mar 10;8(367):ra27. doi: 10.1126/scisignal.aaa0899.
1677 Frameshift mutations of RIZ, but no point mutations in RIZ1 exons in malignant melanomas with deletions in 1p36.Oncogene. 2002 May 2;21(19):3038-42. doi: 10.1038/sj.onc.1205457.
1678 Protein kinase D3 sensitizes RAF inhibitor RAF265 in melanoma cells by preventing reactivation of MAPK signaling.Cancer Res. 2011 Jun 15;71(12):4280-91. doi: 10.1158/0008-5472.CAN-10-3761. Epub 2011 Apr 28.
1679 Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.Stem Cells. 2012 Sep;30(9):1808-18. doi: 10.1002/stem.1160.
1680 Expression of co-factors (SMRT and Trip-1) for retinoic acid receptors in human neuroectodermal cell lines.Biochem Biophys Res Commun. 1997 May 8;234(1):278-82. doi: 10.1006/bbrc.1997.6626.
1681 RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas.Cancer Res. 2007 Apr 1;67(7):3064-73. doi: 10.1158/0008-5472.CAN-06-2301.
1682 Qualitative and quantitative changes in nuclear DNA and phenotypic gene expression in human malignant skin tumors during their progression.Eur J Histochem. 1992;36(3):289-302.
1683 Cyclopalladated compounds containing 2,6-lutidine: Synthesis, spectral and biological studies.J Inorg Biochem. 2020 Feb;203:110944. doi: 10.1016/j.jinorgbio.2019.110944. Epub 2019 Nov 22.
1684 Overexpression of Ras-Related C3 Botulinum Toxin Substrate 2 Radiosensitizes Melanoma Cells In Vitro and In Vivo.Oxid Med Cell Longev. 2019 Jun 2;2019:5254798. doi: 10.1155/2019/5254798. eCollection 2019.
1685 Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.Nat Med. 2012 Aug;18(8):1248-53. doi: 10.1038/nm.2856. Epub 2012 Jul 8.
1686 No evidence of RALGDS mutations in cutaneous melanoma.Melanoma Res. 2007 Dec;17(6):410-2. doi: 10.1097/CMR.0b013e3282ef4178.
1687 Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma.Cancer Res. 2005 Oct 1;65(19):8869-77. doi: 10.1158/0008-5472.CAN-05-1387.
1688 Decreased tissue plasminogen activator and increased plasminogen activator inhibitors and increased activator protein-1 and specific promoter 1 are associated with inhibition of invasion in human A375 melanoma deprived of tyrosine and phenylalanine.Int J Oncol. 2001 Apr;18(4):877-83. doi: 10.3892/ijo.18.4.877.
1689 Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis.Cancer Res. 2006 Aug 15;66(16):7880-8. doi: 10.1158/0008-5472.CAN-06-0254.
1690 HRAS1 proto-oncogene polymorphisms in human malignant melanoma: TaqI defined alleles significantly associated with the disease.Oncogene. 1987;2(1):91-5.
1691 Genetic polymorphism of NK receptors and their ligands in melanoma patients: prevalence of inhibitory over activating signals.Cancer Immunol Immunother. 2005 Feb;54(2):172-8. doi: 10.1007/s00262-004-0575-z. Epub 2004 Jul 10.
1692 Human melanomas of fibroblast and epithelial morphology differ widely in their ability to synthesize retinyl esters.Carcinogenesis. 2002 Nov;23(11):1821-30. doi: 10.1093/carcin/23.11.1821.
1693 Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis.J Biol Chem. 2004 Nov 26;279(48):50537-54. doi: 10.1074/jbc.M406454200. Epub 2004 Sep 23.
1694 On the interplay of telomeres, nevi and the risk of melanoma.PLoS One. 2012;7(12):e52466. doi: 10.1371/journal.pone.0052466. Epub 2012 Dec 27.
1695 mTOR is activated in the majority of malignant melanomas.J Invest Dermatol. 2008 Apr;128(4):980-7. doi: 10.1038/sj.jid.5701074. Epub 2007 Oct 4.
1696 Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets.BMC Cancer. 2008 Jan 22;8:19. doi: 10.1186/1471-2407-8-19.
1697 RIN1 exhibits oncogenic property to suppress apoptosis and its aberrant accumulation associates with poor prognosis in melanoma.Tumour Biol. 2012 Oct;33(5):1511-8. doi: 10.1007/s13277-012-0402-7. Epub 2012 May 25.
1698 Genetic variant of the human homologous recombination-associated gene RMI1 (S455N) impacts the risk of AML/MDS and malignant melanoma.Cancer Lett. 2007 Dec 8;258(1):38-44. doi: 10.1016/j.canlet.2007.08.005. Epub 2007 Sep 27.
1699 Eosinophil-cationic protein - a novel liquid prognostic biomarker in melanoma.BMC Cancer. 2019 Mar 7;19(1):207. doi: 10.1186/s12885-019-5384-z.
1700 Weighted correlation network and differential expression analyses identify candidate genes associated with BRAF gene in melanoma.BMC Med Genet. 2019 Mar 29;20(1):54. doi: 10.1186/s12881-019-0791-1.
1701 RNASET2 as a tumor antagonizing gene in a melanoma cancer model.Oncol Res. 2008;17(2):69-74. doi: 10.3727/096504008784523658.
1702 Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer.Cancer Res. 2007 Sep 1;67(17):8172-9. doi: 10.1158/0008-5472.CAN-07-0045.
1703 Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display.Cancer Res. 2007 Apr 15;67(8):3555-9. doi: 10.1158/0008-5472.CAN-06-2763.
1704 BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma.Cell Death Differ. 2012 Dec;19(12):2029-39. doi: 10.1038/cdd.2012.94. Epub 2012 Aug 3.
1705 Functional genomics of calcium channels in human melanoma cells.Int J Cancer. 2007 Jul 1;121(1):55-65. doi: 10.1002/ijc.22621.
1706 Expression patterns of S100 proteins in melanocytes and melanocytic lesions.Melanoma Res. 2009 Aug;19(4):215-25. doi: 10.1097/CMR.0b013e32832c6358.
1707 Prediction and Analysis of Skin Cancer Progression using Genomics Profiles of Patients.Sci Rep. 2019 Oct 31;9(1):15790. doi: 10.1038/s41598-019-52134-4.
1708 Metformin Treatment Suppresses Melanoma Cell Growth and Motility Through Modulation of microRNA Expression.Cancers (Basel). 2019 Feb 11;11(2):209. doi: 10.3390/cancers11020209.
1709 Expression analysis of the epithelial Na+ channel delta subunit in human melanoma G-361 cells.Biochem Biophys Res Commun. 2008 Feb 8;366(2):489-92. doi: 10.1016/j.bbrc.2007.11.177. Epub 2007 Dec 10.
1710 The SNAIL family member SCRATCH1 is not expressed in human tumors.Oncol Rep. 2010 Feb;23(2):523-9.
1711 Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism.Int J Biochem Cell Biol. 2009 Jun;41(6):1323-31. doi: 10.1016/j.biocel.2008.11.008. Epub 2008 Dec 6.
1712 A PDZ Protein MDA-9/Syntenin: As a Target for Cancer Therapy.Comput Struct Biotechnol J. 2019 Jan 8;17:136-141. doi: 10.1016/j.csbj.2019.01.002. eCollection 2019.
1713 Semaphorin 3E expression correlates inversely with Plexin D1 during tumor progression.Am J Pathol. 2008 Dec;173(6):1873-81. doi: 10.2353/ajpath.2008.080136. Epub 2008 Oct 30.
1714 Plexin C1, a receptor for semaphorin 7a, inactivates cofilin and is a potential tumor suppressor for melanoma progression.J Invest Dermatol. 2009 Apr;129(4):954-63. doi: 10.1038/jid.2008.329. Epub 2008 Nov 6.
1715 Knockdown of STAT3 targets a subpopulation of invasive melanoma stem-like cells.Cell Biol Int. 2019 Jun;43(6):613-622. doi: 10.1002/cbin.11134. Epub 2019 Apr 30.
1716 Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma.Clin Cancer Res. 2005 Sep 1;11(17):6400-7. doi: 10.1158/1078-0432.CCR-05-0306.
1717 Metastatic Melanoma Cells Rely on Sestrin2 to Acquire Anoikis Resistance via Detoxifying Intracellular ROS.J Invest Dermatol. 2020 Mar;140(3):666-675.e2. doi: 10.1016/j.jid.2019.07.720. Epub 2019 Aug 31.
1718 Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming.Clin Epigenetics. 2019 Mar 8;11(1):43. doi: 10.1186/s13148-019-0644-y.
1719 Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma.Front Pharmacol. 2019 Apr 30;10:443. doi: 10.3389/fphar.2019.00443. eCollection 2019.
1720 Mitogen-activated protein kinase dependency in BRAF/RAS wild-type melanoma: A rationale for combination inhibitors.Pigment Cell Melanoma Res. 2020 Mar;33(2):345-357. doi: 10.1111/pcmr.12824. Epub 2019 Sep 25.
1721 The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors.Sci Rep. 2019 May 17;9(1):7548. doi: 10.1038/s41598-019-44039-z.
1722 Siglec-9 Regulates an Effector Memory CD8(+) T-cell Subset That Congregates in the Melanoma Tumor Microenvironment.Cancer Immunol Res. 2019 May;7(5):707-718. doi: 10.1158/2326-6066.CIR-18-0505. Epub 2019 Apr 15.
1723 Inhibition of the prohormone convertase subtilisin-kexin isoenzyme-1 induces apoptosis in human melanoma cells.J Invest Dermatol. 2014 Jan;134(1):168-175. doi: 10.1038/jid.2013.282. Epub 2013 Jun 27.
1724 Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells.J Biol Chem. 2010 Dec 17;285(51):40333-41. doi: 10.1074/jbc.M110.151076. Epub 2010 Oct 18.
1725 Slit3 inhibits activator protein 1-mediated migration of malignant melanoma cells.Int J Mol Med. 2011 Nov;28(5):721-6. doi: 10.3892/ijmm.2011.742. Epub 2011 Jul 8.
1726 SMAD signaling promotes melanoma metastasis independently of phenotype switching.J Clin Invest. 2019 Apr 30;129(7):2702-2716. doi: 10.1172/JCI94295.
1727 Development of a yeast-based system to identify new hBRAFV600E functional interactors.Oncogene. 2019 Feb;38(8):1355-1366. doi: 10.1038/s41388-018-0496-5. Epub 2018 Sep 20.
1728 Recurrent vulvar melanoma in a patient with neurofibromatosis and gastrointestinal stromal tumour.BMJ Case Rep. 2019 Jan 20;12(1):e224744. doi: 10.1136/bcr-2018-224744.
1729 The role of microRNA-30a and downstream snail1 on the growth and metastasis of melanoma tumor.Iran J Basic Med Sci. 2019 May;22(5):534-540. doi: 10.22038/IJBMS.2019.32317.7745.
1730 Impact of NAD(P)H:quinone oxidoreductase-1 on pigmentation.J Invest Dermatol. 2010 Mar;130(3):784-92. doi: 10.1038/jid.2009.280. Epub 2009 Sep 17.
1731 Cutaneous neoplasms composed of melanoma and carcinoma: A rare but important diagnostic pitfall and review of the literature.J Cutan Pathol. 2020 Jan;47(1):36-46. doi: 10.1111/cup.13551. Epub 2019 Aug 11.
1732 Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development.J Natl Cancer Inst. 2006 Aug 2;98(15):1060-7. doi: 10.1093/jnci/djj299.
1733 Overlapping genetic architecture between Parkinson disease and melanoma.Acta Neuropathol. 2020 Feb;139(2):347-364. doi: 10.1007/s00401-019-02110-z. Epub 2019 Dec 16.
1734 Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth.Mol Ther. 2010 Jul;18(7):1275-83. doi: 10.1038/mt.2010.79. Epub 2010 May 4.
1735 Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.J Exp Clin Cancer Res. 2019 Sep 13;38(1):405. doi: 10.1186/s13046-019-1389-3.
1736 Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer.BMC Cancer. 2019 Dec 18;19(1):1230. doi: 10.1186/s12885-019-6441-3.
1737 SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant.Cancer Res. 2004 Aug 15;64(16):5556-9. doi: 10.1158/0008-5472.CAN-04-1669.
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1741 Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line.Biochemistry. 1996 Apr 23;35(16):5166-74. doi: 10.1021/bi960239l.
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1745 The special stemness functions of Tbx3 in stem cells and cancer development.Semin Cancer Biol. 2019 Aug;57:105-110. doi: 10.1016/j.semcancer.2018.09.010. Epub 2018 Sep 27.
1746 Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.Carcinogenesis. 2011 Oct;32(10):1467-73. doi: 10.1093/carcin/bgr138. Epub 2011 Jul 18.
1747 TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.Cancer Res. 2019 Feb 1;79(3):482-494. doi: 10.1158/0008-5472.CAN-18-1214. Epub 2018 Dec 11.
1748 Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma.J Invest Dermatol. 2013 May;133(5):1278-85. doi: 10.1038/jid.2012.493. Epub 2013 Feb 14.
1749 Knockdown THOC2 suppresses the proliferation and invasion of melanoma.Bioengineered. 2019 Dec;10(1):635-645. doi: 10.1080/21655979.2019.1685727.
1750 Replacing Mn(2+) with Co(2+) in human arginase i enhances cytotoxicity toward l-arginine auxotrophic cancer cell lines.ACS Chem Biol. 2010 Mar 19;5(3):333-42. doi: 10.1021/cb900267j.
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1759 Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities.Oncogene. 2001 Apr 26;20(18):2243-53. doi: 10.1038/sj.onc.1204314.
1760 TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4.J Exp Clin Cancer Res. 2019 Mar 28;38(1):137. doi: 10.1186/s13046-019-1138-7.
1761 Growth-regulated oncogene-1 expression is associated with angiogenesis and lymph node metastasis in human oral cancer.Oncology. 2004;66(4):316-22. doi: 10.1159/000078333.
1762 Over-expression of the testis-specific gene TSGA10 in cancers and its immunogenicity.Microbiol Immunol. 2004;48(4):339-45. doi: 10.1111/j.1348-0421.2004.tb03515.x.
1763 Tspan8 is expressed in breast cancer and regulates E-cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles.J Pathol. 2019 Aug;248(4):421-437. doi: 10.1002/path.5281. Epub 2019 Jun 18.
1764 Identification and characterization of TPARM gene in silico.Int J Oncol. 2003 Oct;23(4):1213-7.
1765 ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity.Nat Commun. 2018 Feb 14;9(1):676. doi: 10.1038/s41467-018-03080-8.
1766 Targeting LMW-PTP to sensitize melanoma cancer cells toward chemo- and radiotherapy.Cancer Med. 2018 May;7(5):1933-1943. doi: 10.1002/cam4.1435. Epub 2018 Mar 24.
1767 ACTN4 regulates the stability of RIPK1 in melanoma.Oncogene. 2018 Jul;37(29):4033-4045. doi: 10.1038/s41388-018-0260-x. Epub 2018 Apr 30.
1768 Expression of orphan GPR56 correlates with tumor progression in human epithelial ovarian cancer.Neoplasma. 2017;64(1):32-39. doi: 10.4149/neo_2017_104.
1769 Long non-coding RNA H19 promotes glucose metabolism and cell growth in malignant melanoma via miR-106a-5p/E2F3 axis.J Cancer Res Clin Oncol. 2018 Mar;144(3):531-542. doi: 10.1007/s00432-018-2582-z. Epub 2018 Jan 19.
1770 Unclassified sclerosing malignant melanomas with AKAP9-BRAF gene fusion: a report of two cases and review of BRAF fusions in melanocytic tumors.Virchows Arch. 2018 Mar;472(3):469-476. doi: 10.1007/s00428-017-2290-0. Epub 2018 Feb 21.
1771 A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q.Hum Genet. 2012 Jan;131(1):77-85. doi: 10.1007/s00439-011-1048-z. Epub 2011 Jun 26.
1772 Recombinant DNA technology for melanoma immunotherapy: anti-Id DNA vaccines targeting high molecular weight melanoma-associated antigen.Mol Biotechnol. 2014 Nov;56(11):1032-9. doi: 10.1007/s12033-014-9782-9.
1773 The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2.
1774 JWA suppresses the invasion of human breast carcinoma cells by downregulating the expression of CXCR4.Mol Med Rep. 2018 Jun;17(6):8137-8144. doi: 10.3892/mmr.2018.8866. Epub 2018 Apr 11.
1775 PKC phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration.BMC Neurosci. 2018 Nov 29;19(1):76. doi: 10.1186/s12868-018-0479-z.
1776 Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma.Metallomics. 2019 Aug 1;11(8):1430-1440. doi: 10.1039/c9mt00042a. Epub 2019 Jul 18.
1777 EV20-mediated delivery of cytotoxic auristatin MMAF exhibits potent therapeutic efficacy in cutaneous melanoma.J Control Release. 2018 May 10;277:48-56. doi: 10.1016/j.jconrel.2018.03.016. Epub 2018 Mar 14.
1778 A commensal strain of Staphylococcus epidermidis protects against skin neoplasia.Sci Adv. 2018 Feb 28;4(2):eaao4502. doi: 10.1126/sciadv.aao4502. eCollection 2018 Feb.
1779 Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.Ann Oncol. 2017 Mar 1;28(3):634-641. doi: 10.1093/annonc/mdw641.
1780 Genome-wide association study identifies three new melanoma susceptibility loci.Nat Genet. 2011 Oct 9;43(11):1108-13. doi: 10.1038/ng.959.
1781 CADM1 is a TWIST1-regulated suppressor of invasion and survival.Cell Death Dis. 2019 Mar 25;10(4):281. doi: 10.1038/s41419-019-1515-3.
1782 The function of FAK/CCDC80/E-cadherin pathway in the regulation of B16F10 cell migration.Oncol Lett. 2018 Oct;16(4):4761-4767. doi: 10.3892/ol.2018.9159. Epub 2018 Jul 17.
1783 CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells.J Invest Dermatol. 2014 Dec;134(12):2947-2956. doi: 10.1038/jid.2014.258. Epub 2014 Jun 18.
1784 CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation.Oncogene. 2016 Sep 22;35(38):5056-5069. doi: 10.1038/onc.2016.67. Epub 2016 Apr 4.
1785 Gene expression screening identifies CDCA5 as a potential therapeutic target in acral melanoma.Hum Pathol. 2018 May;75:137-145. doi: 10.1016/j.humpath.2018.02.009. Epub 2018 Feb 13.
1786 Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.Clin Cancer Res. 2018 Jan 15;24(2):433-444. doi: 10.1158/1078-0432.CCR-17-1444. Epub 2017 Sep 15.
1787 Potential predictive value of cofilin-1 for metastasis occurrence in a small cohort of Argentinian patients with mid-low Breslow thickness melanoma.Pathol Res Pract. 2019 Oct;215(10):152582. doi: 10.1016/j.prp.2019.152582. Epub 2019 Aug 8.
1788 The Concomitant Expression of Human Endogenous Retroviruses and Embryonic Genes in Cancer Cells under Microenvironmental Changes is a Potential Target for Antiretroviral Drugs.Cancer Microenviron. 2019 Dec;12(2-3):105-118. doi: 10.1007/s12307-019-00231-3. Epub 2019 Nov 5.
1789 FT-IR Spectroscopy Study in Early Diagnosis of Skin Cancer.In Vivo. 2017 Nov-Dec;31(6):1131-1137. doi: 10.21873/invivo.11179.
1790 CXCL5 as Regulator of Neutrophil Function inCutaneous Melanoma.J Invest Dermatol. 2019 Jan;139(1):186-194. doi: 10.1016/j.jid.2018.07.006. Epub 2018 Oct 4.
1791 Cytotoxicity of Nubein6.8 peptide isolated from the snake venom of Naja nubiae on melanoma and ovarian carcinoma cell lines.Toxicon. 2019 Oct;168:22-31. doi: 10.1016/j.toxicon.2019.06.220. Epub 2019 Jun 21.
1792 Prognostic genes of melanoma identified by weighted gene co-expression network analysis and drug repositioning using a network-based method.Oncol Lett. 2019 Dec;18(6):6066-6078. doi: 10.3892/ol.2019.10961. Epub 2019 Oct 4.
1793 EMP2 acts as a suppressor of melanoma and is negatively regulated by mTOR-mediated autophagy.J Cancer. 2019 Jun 9;10(16):3582-3592. doi: 10.7150/jca.30342. eCollection 2019.
1794 Overexpression of microRNA-612 Restrains the Growth, Invasion, and Tumorigenesis of Melanoma Cells by Targeting Espin.Mol Cells. 2018 Feb 28;41(2):119-126. doi: 10.14348/molcells.2018.2235. Epub 2018 Jan 29.
1795 IL-12/23p40 overproduction by dendritic cells leads to an increased Th1 and Th17 polarization in a model of Yersinia enterocolitica-induced reactive arthritis in TNFRp55-/- mice.PLoS One. 2018 Mar 1;13(3):e0193573. doi: 10.1371/journal.pone.0193573. eCollection 2018.
1796 MicroRNA-22 targets FMNL2 to inhibit melanoma progression via the regulation of the Wnt/-catenin signaling pathway and epithelial-mesenchymal transition.Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5332-5342. doi: 10.26355/eurrev_201906_18200.
1797 Novel circular RNA, hsa_circ_0025039 promotes cell growth, invasion and glucose metabolism in malignant melanoma via the miR-198/CDK4 axis.Biomed Pharmacother. 2018 Dec;108:165-176. doi: 10.1016/j.biopha.2018.08.152. Epub 2018 Sep 13.
1798 -1,3-Galactosyl-O-Glycosyl-Glycoprotein -1,6-N-Acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.Oncol Res. 2018 Apr 10;26(3):431-444. doi: 10.3727/096504017X15031557924123. Epub 2017 Sep 18.
1799 GLT8D1 overexpression as a novel prognostic biomarker in human cutaneous melanoma.Melanoma Res. 2019 Dec;29(6):612-620. doi: 10.1097/CMR.0000000000000631.
1800 Nuclear pseudoinclusions in melanoma cells: prognostic fact or artifact? The possible role of Golgi phosphoprotein 3 overexpression in nuclear pseudoinclusions generation.Pathol Int. 2018 Feb;68(2):117-122. doi: 10.1111/pin.12629. Epub 2018 Jan 29.
1801 ABCB5 promotes melanoma metastasis through enhancing NF-B p65 protein stability.Biochem Biophys Res Commun. 2017 Oct 7;492(1):18-26. doi: 10.1016/j.bbrc.2017.08.052. Epub 2017 Aug 15.
1802 Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)-dependent stabilization of hypoxia-inducible factor 1- and 2-.J Cell Biochem. 2019 Nov;120(11):19124-19136. doi: 10.1002/jcb.29240. Epub 2019 Jul 16.
1803 High G2 and S-phase expressed 1 expression promotes acral melanoma progression and correlates with poor clinical prognosis.Cancer Sci. 2018 Jun;109(6):1787-1798. doi: 10.1111/cas.13607. Epub 2018 May 11.
1804 Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells.Cell Death Differ. 2018 Nov;25(11):2010-2022. doi: 10.1038/s41418-018-0090-y. Epub 2018 Mar 7.
1805 Immune-Checkpoint Blockade Opposes CD8(+) T-cell Suppression in Human and Murine Cancer.Cancer Immunol Res. 2019 Mar;7(3):510-525. doi: 10.1158/2326-6066.CIR-18-0054. Epub 2019 Feb 6.
1806 Identification of Catechol-Type Diphenylbutadiene as a Tyrosinase-Activated Pro-oxidative Chemosensitizer against Melanoma A375 Cells via Glutathione S-Transferase Inhibition.J Agric Food Chem. 2019 Aug 14;67(32):9060-9069. doi: 10.1021/acs.jafc.9b02875. Epub 2019 Aug 1.
1807 Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.Nat Med. 2019 Dec;25(12):1916-1927. doi: 10.1038/s41591-019-0654-5. Epub 2019 Dec 2.
1808 Melanoma induced immunosuppression is mediated by hematopoietic dysregulation.Oncoimmunology. 2017 Dec 14;7(3):e1408750. doi: 10.1080/2162402X.2017.1408750. eCollection 2018.
1809 Genetic variation in IRF4 expression modulates growth characteristics, tyrosinase expression and interferon-gamma response in melanocytic cells.Pigment Cell Melanoma Res. 2018 Jan;31(1):51-63. doi: 10.1111/pcmr.12620. Epub 2017 Oct 23.
1810 Catalase-like metal-organic framework nanoparticles to enhance radiotherapy in hypoxic cancer and prevent cancer recurrence.Chem Sci. 2019 Apr 25;10(22):5773-5778. doi: 10.1039/c9sc00747d. eCollection 2019 Jun 14.
1811 Inhibition of Age-Related Therapy Resistance in Melanoma by Rosiglitazone-Mediated Induction of Klotho.Clin Cancer Res. 2017 Jun 15;23(12):3181-3190. doi: 10.1158/1078-0432.CCR-17-0201. Epub 2017 Feb 23.
1812 BRAF peptide vaccine facilitates therapy of murine BRAF-mutant melanoma.Cancer Immunol Immunother. 2018 Feb;67(2):299-310. doi: 10.1007/s00262-017-2079-7. Epub 2017 Nov 1.
1813 Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells.J Radiat Res. 2017 Nov 1;58(6):765-771. doi: 10.1093/jrr/rrx022.
1814 Overexpression of microRNA?1 inhibits the growth and metastasis of melanoma cells by targeting MKK3.Mol Med Rep. 2019 Aug;20(2):1797-1807. doi: 10.3892/mmr.2019.10408. Epub 2019 Jun 20.
1815 Association of Time From Primary Diagnosis to First Distant Relapse of Metastatic Melanoma With Progression of Disease and Survival.JAMA Dermatol. 2019 Jun 1;155(6):673-678. doi: 10.1001/jamadermatol.2019.0425.
1816 Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression.Front Med (Lausanne). 2017 Mar 17;4:30. doi: 10.3389/fmed.2017.00030. eCollection 2017.
1817 Elevated cyclic AMP levels promote BRAF(CA)/Pten(-/-) mouse melanoma growth but pCREB is negatively correlated with human melanoma progression.Cancer Lett. 2018 Feb 1;414:268-277. doi: 10.1016/j.canlet.2017.11.027. Epub 2017 Nov 24.
1818 New MSC: MSCs as pericytes are Sentinels and gatekeepers.J Orthop Res. 2017 Jun;35(6):1151-1159. doi: 10.1002/jor.23560. Epub 2017 Apr 11.
1819 Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation.Oncogene. 2019 May;38(19):3763-3764. doi: 10.1038/s41388-019-0679-8.
1820 Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma.J Invest Dermatol. 2017 Apr;137(4):910-920. doi: 10.1016/j.jid.2016.11.029. Epub 2016 Dec 18.
1821 Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma.J Med Virol. 2019 Sep;91(9):1702-1706. doi: 10.1002/jmv.25501. Epub 2019 Jun 24.
1822 Gene Expression and Methylation Analysis in Melanomas and Melanocytes From the Same Patient: Loss of NPM2 Expression Is a Potential Immunohistochemical Marker for Melanoma.Front Oncol. 2019 Jan 21;8:675. doi: 10.3389/fonc.2018.00675. eCollection 2018.
1823 Photothermal therapy mediated by phase-transformation nanoparticles facilitates delivery of anti-PD1 antibody and synergizes with antitumor immunotherapy for melanoma.J Control Release. 2019 Jul 28;306:15-28. doi: 10.1016/j.jconrel.2019.05.036. Epub 2019 May 25.
1824 A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression.Nat Commun. 2018 Jan 31;9(1):461. doi: 10.1038/s41467-018-02851-7.
1825 miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells.Onco Targets Ther. 2018 Apr 5;11:1909-1920. doi: 10.2147/OTT.S152362. eCollection 2018.
1826 Peli1 Modulates the Subcellular Localization and Activity of Mdmx.Cancer Res. 2018 Jun 1;78(11):2897-2910. doi: 10.1158/0008-5472.CAN-17-3531. Epub 2018 Mar 9.
1827 Common sequence variants on 20q11.22 confer melanoma susceptibility.Nat Genet. 2008 Jul;40(7):838-40. doi: 10.1038/ng.163. Epub 2008 May 18.
1828 Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma.J Dermatol. 2018 May;45(5):571-579. doi: 10.1111/1346-8138.14278. Epub 2018 Mar 3.
1829 Long non-coding RNA CASC2 inhibits tumorigenesis via the miR-181a/PLXNC1 axis in melanoma.Acta Biochim Biophys Sin (Shanghai). 2018 Mar 1;50(3):263-272. doi: 10.1093/abbs/gmx148.
1830 BRAF inhibition sensitizes melanoma cells to -amanitin via decreased RNA polymerase II assembly.Sci Rep. 2019 May 23;9(1):7779. doi: 10.1038/s41598-019-44112-7.
1831 Somatic mutations of PREX2 gene in patients with hepatocellular carcinoma.Sci Rep. 2019 Feb 22;9(1):2552. doi: 10.1038/s41598-018-36810-5.
1832 Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib.Oncotarget. 2017 Dec 9;8(69):113472-113493. doi: 10.18632/oncotarget.23052. eCollection 2017 Dec 26.
1833 RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1038/s41598-017-18851-4.
1834 Enhanced intratumoral expression of RNF2 is a favorable prognostic factor for patients with cutaneous melanoma?.Oncotarget. 2018 Apr 3;9(25):17656-17663. doi: 10.18632/oncotarget.24825. eCollection 2018 Apr 3.
1835 Phase II Study of Everolimus in Metastatic Malignant Melanoma (NCCTG-N0377, Alliance).Oncologist. 2018 Aug;23(8):887-e94. doi: 10.1634/theoncologist.2018-0100. Epub 2018 Apr 17.
1836 SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma.Oncotarget. 2018 Jan 9;9(7):7567-7581. doi: 10.18632/oncotarget.24085. eCollection 2018 Jan 26.
1837 Pathogenic Germline Variants in 10,389 Adult Cancers.Cell. 2018 Apr 5;173(2):355-370.e14. doi: 10.1016/j.cell.2018.03.039.
1838 Molecular Mechanisms by Which Selenoprotein K Regulates Immunity and Cancer.Biol Trace Elem Res. 2019 Nov;192(1):60-68. doi: 10.1007/s12011-019-01774-8. Epub 2019 Jun 11.
1839 Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus.Cell Cycle. 2017 Aug 18;16(16):1502-1508. doi: 10.1080/15384101.2016.1249548. Epub 2017 Jan 5.
1840 Identification of a gene expression signature associated with the metastasis suppressor function of NME1: prognostic value in human melanoma.Lab Invest. 2018 Mar;98(3):327-338. doi: 10.1038/labinvest.2017.108. Epub 2017 Oct 23.
1841 TNF-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes.Sci Rep. 2019 Oct 14;9(1):14740. doi: 10.1038/s41598-019-51333-3.
1842 STAT3 and STAT5 Targeting for Simultaneous Management of Melanoma and Autoimmune Diseases.Cancers (Basel). 2019 Sep 27;11(10):1448. doi: 10.3390/cancers11101448.
1843 The Construction and Comprehensive Analysis of ceRNA Networks and Tumor-Infiltrating Immune Cells in Bone Metastatic Melanoma.Front Genet. 2019 Sep 25;10:828. doi: 10.3389/fgene.2019.00828. eCollection 2019.
1844 Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma tumour model.Artif Cells Nanomed Biotechnol. 2018;46(sup2):75-86. doi: 10.1080/21691401.2018.1452021. Epub 2018 Apr 1.
1845 Design, synthesis and evaluation of novel sulfonamides as potential anticancer agents.Comput Biol Chem. 2018 Jun;74:294-303. doi: 10.1016/j.compbiolchem.2018.04.006. Epub 2018 Apr 10.
1846 Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma.Genes Chromosomes Cancer. 2018 Jun;57(6):294-303. doi: 10.1002/gcc.22528. Epub 2018 Feb 21.
1847 TRAF3-interacting protein 3, a new oncotarget, promotes tumor growth in melanoma.Melanoma Res. 2018 Jun;28(3):185-194. doi: 10.1097/CMR.0000000000000440.
1848 The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy.J Invest Dermatol. 2018 Jan;138(1):159-170. doi: 10.1016/j.jid.2017.07.850. Epub 2017 Sep 9.