Details of the Drug | DrugMAP

General Information of Drug (ID: DMH5LME)

Drug Name

Levoleucovorin

Synonyms

FUSILEV (TN)

Indication

Disease Entry	ICD 11	Status	REF
Anemia	3A00-3A9Z	Approved	[1]
Colon adenocarcinoma	N.A.	Approved	[2]
Colorectal carcinoma	N.A.	Approved	[2]
Non-small-cell lung cancer	2C25.Y	Approved	[2]
Pervasive developmental disorder	6A00-6A0Z	Approved	[2]
Pneumocystis pneumonia	CA40.20	Approved	[2]
Rectal adenocarcinoma	2B92	Approved	[2]
Rectum mucinous adenocarcinoma	N.A.	Approved	[2]
Colon cancer	2B90.Z	Investigative	[2]
Colon mucinous adenocarcinoma	N.A.	Investigative	[2]
Gastric cancer	2B72	Investigative	[2]
Megaloblastic anemia	N.A.	Investigative	[2]
Methotrexate toxicity	N.A.	Investigative	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C20H23N7O7
Canonical SMILES: C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
InChI: 1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
InChIKey: VVIAGPKUTFNRDU-STQMWFEESA-N

Cross-matching ID

PubChem CID: 135398559
ChEBI ID: CHEBI:63606
CAS Number: 68538-85-2
TTD ID: D0Q6LA

Combinatorial Drugs (CBD)

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Repurposed Drugs (RPD)

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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Levoleucovorin FDA Label