General Information of Disease (ID: DISVC52G)

Disease Name Colon cancer
Synonyms
malignant neoplasm of the colon; malignant tumor of the colon; malignant tumour of the colon; colon cancer; malignant neoplasm of colon; malignant colon neoplasm; malignant colonic tumour; cancer of colon; colon tumor, malignant; malignant colonic tumor; malignant tumour of colon; malignant colonic neoplasm; colon neoplasm, malignant; malignant tumor of colon; malignant colon tumor; malignant colon tumour
Disease Class 2B90: Colon cancer
Definition A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma.
Disease Hierarchy
DISNH7P9: Colorectal cancer
DISAT1Z9: Advanced cancer
DISSZ04P: Colonic neoplasm
DISVC52G: Colon cancer
ICD Code
ICD-11
ICD-11: 2B90.Z
Expand ICD-9
153154
Disease Identifiers
MONDO ID
MONDO_0021063
MESH ID
D003110
UMLS CUI
C0007102
MedGen ID
2839
HPO ID
HP:0003003
SNOMED CT ID
363406005

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 33 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aldesleukin DM4YMIS Approved NA [1]
Aspirin DM672AH Approved Small molecular drug [2]
Bavencio DMU9C8F Approved Monoclonal antibody [3]
Bevacizumab DMSD1UN Approved Monoclonal antibody [4]
Bortezomib DMNO38U Approved Small molecular drug [5]
Capecitabine DMTS85L Approved Small molecular drug [6]
Celecoxib DM6LOQU Approved Small molecular drug [7]
Cetuximab DMLNCE0 Approved Antibody [4]
Citalopram DM2G9AE Approved Small molecular drug [8]
Eflornithine DMJOQM3 Approved Small molecular drug [9]
Erlotinib DMCMBHA Approved Small molecular drug [10]
Everolimus DM8X2EH Approved Small molecular drug [11]
Floxuridine DM04LR2 Approved Small molecular drug [12]
Fludarabine DMVRLT7 Approved Small molecular drug [13]
Fluorouracil DMUM7HZ Approved Small molecular drug [14]
Gefitinib DM15F0X Approved Small molecular drug [15]
Gemcitabine DMSE3I7 Approved Small molecular drug [16]
Hydroxychloroquine DMSIVND Approved Small molecular drug [17]
Irinotecan DMP6SC2 Approved Small molecular drug [18]
Lenalidomide DM6Q7U4 Approved Small molecular drug [19]
Leucovorin DMUAZWG Approved Small molecular drug [20]
Levamisole DM5EN79 Approved Small molecular drug [21]
Levoleucovorin DMH5LME Approved Small molecular drug [22]
Mitomycin DMH0ZJE Approved Small molecular drug [23]
Oxaliplatin DMQNWRD Approved Small molecular drug [24]
Rosuvastatin DMMIQ7G Approved Small molecular drug [25]
Salicyclic acid DM2F8XZ Approved Small molecular drug [26]
Selpercatinib DMZR15V Approved NA [27]
Sulindac DM2QHZU Approved Small molecular drug [28]
Thalidomide DM70BU5 Approved Small molecular drug [29]
Trifluridine DMG2YBD Approved Small molecular drug [30]
Ursodeoxycholic acid DMCUT21 Approved Small molecular drug [31]
Vidarabine DM0N85H Approved Small molecular drug [32]
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⏷ Show the Full List of 33 Drug(s)
This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
TVB-2640 DM19GUH Phase 2 NA [33]
CAR-T Cells targeting EpCAM DMREQCF Phase 1/2 CAR T Cell Therapy [34]
ADXS-NEO DMFJ1OW Phase 1 Vaccine [33]
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This Disease is Treated as An Indication in 1 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
PMID28460551-Compound-1 DMHV75N Patented Small molecular drug [35]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 2 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
GSK184072 DMMIR1K Discontinued in Phase 2 Small molecular drug [36]
NR-LU-13 DMWCEMI Terminated NA [39]
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This Disease is Treated as An Indication in 2 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
EPZ0330456 DMUKVYL Preclinical Small molecular drug [37]
PT630 DM9SY8E Preclinical Peptide [38]
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This Disease is Treated as An Indication in 8 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
131I-COU-1 DM0H5Y1 Investigative NA [40]
A33-Ac-225 DM7H52A Investigative NA [40]
ARX-Trail DMAGSV1 Investigative NA [40]
COU-1 DMKNLJZ Investigative NA [40]
ET-003 DMSKS97 Investigative NA [40]
H2TFPC-SGlc DMGSLZE Investigative NA [40]
MDC-1231 DMCK4DL Investigative NA [40]
VLN-244 DMPBC9B Investigative NA [40]
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⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 794 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCC3 TTVLG21 Limited Biomarker [42]
ACTG1 TTGAZF9 Limited Biomarker [43]
ADORA2B TTNE7KG Limited Altered Expression [44]
AKR1B1 TTFBNVI Limited Biomarker [45]
ALOX12B TTQ4QQH Limited Biomarker [46]
ANXA10 TT0NL6U Limited Biomarker [47]
AQP1 TTSF1KH Limited Biomarker [48]
AREG TT76B3W Limited Biomarker [49]
BAX TTQ57WJ Limited Biomarker [50]
BGN TT0JPVF Limited Biomarker [51]
BRIP1 TTZV7LJ Limited Genetic Variation [52]
CCKBR TTVFO0U Limited Biomarker [53]
CD276 TT6CQUM Limited Biomarker [54]
CDH1 TTLAWO6 Limited Genetic Variation [55]
CRYZ TTP6UO8 Limited Genetic Variation [56]
CXCL2 TTZF0K2 Limited Altered Expression [57]
CXCR1 TTMWT8Z Limited Genetic Variation [58]
CXCR3 TT1UCIJ Limited Biomarker [59]
CYP24A1 TT82UI1 Limited Altered Expression [60]
CYP26A1 TTD7Q0R Limited Biomarker [61]
CYP3A4 TTWP7HQ Limited Altered Expression [62]
DDX5 TTZKPVC Limited Altered Expression [63]
DICER1 TTTEOPU Limited Altered Expression [64]
DNMT1 TT6S2FE Limited Biomarker [65]
EIF2AK3 TT79U1M Limited Biomarker [66]
EIF4E TTZGCP6 Limited Altered Expression [67]
EPHA7 TTAHTVG Limited Biomarker [68]
EPHB1 TT8MDAC Limited Genetic Variation [69]
ERBB2 TTR5TV4 Limited Biomarker [70]
ESR2 TTOM3J0 Limited Altered Expression [71]
ESRRA TTPNQAC Limited Biomarker [72]
EZR TTE47YC Limited Altered Expression [73]
F2RL1 TTQR74A Limited Biomarker [74]
FGF18 TT6ICRA Limited Altered Expression [75]
FGFR4 TT1KX2S Limited Biomarker [76]
FOLR1 TTVC37M Limited Biomarker [77]
GADD45B TTMDW9L Limited Biomarker [78]
GAN TT6WNG2 Limited Genetic Variation [79]
GNRHR TT8R70G Limited Biomarker [80]
GRIK2 TT0K5RG Limited Biomarker [81]
GRPR TTC1MVT Limited Biomarker [82]
GSK3B TTRSMW9 Limited Biomarker [83]
GUCY2C TTLDPRG Limited Genetic Variation [84]
HCAR2 TTWNV8U Limited Altered Expression [85]
HDAC2 TTSHTOI Limited Altered Expression [86]
HNF1A TT01M3K Limited Altered Expression [87]
IDO1 TTZJYKH Limited Altered Expression [88]
IGFBP7 TTUQ01B Limited Biomarker [89]
IL1RN TT6GSR3 Limited Biomarker [90]
IL23A TTC1GLB Limited Biomarker [91]
IRF3 TTYR7OH Limited Genetic Variation [92]
IRS2 TTF95B8 Limited Biomarker [93]
ITGA2 TTSJ542 Limited Altered Expression [94]
JUN TTS7IR5 Limited Biomarker [95]
KAT2B TTVK7SB Limited Biomarker [96]
KLRG1 TT299E6 Limited Biomarker [97]
LEP TTBJEZ5 Limited Altered Expression [98]
LTF TTSZDQU Limited Biomarker [99]
MAP3K9 TTUNSIX Limited Genetic Variation [100]
MAPK7 TTU6FSC Limited Altered Expression [101]
MMP1 TTMX39J Limited Biomarker [102]
MMP7 TTMTWOS Limited Biomarker [103]
MSI1 TTSM4BA Limited Biomarker [104]
MTA1 TTO4HUS Limited Biomarker [105]
MTDH TTH6SA5 Limited Biomarker [106]
MUC1 TTBHFYQ Limited Altered Expression [107]
MUC17 TTVO0JU Limited Altered Expression [108]
MYD88 TTB6Q2O Limited Altered Expression [109]
NOS2 TTF10I9 Limited Altered Expression [110]
NRP1 TTIPJCB Limited Biomarker [111]
NTSR1 TTTUMEP Limited Biomarker [112]
PAK1 TTFN95D Limited Biomarker [113]
PBK TTMY6BZ Limited Altered Expression [114]
PLG TTP86E2 Limited Biomarker [115]
PTGER4 TT79WV3 Limited Biomarker [116]
PTK2 TTON5IT Limited Biomarker [117]
PTK6 TT6TH8V Limited Biomarker [118]
PTN TTA9EJK Limited Altered Expression [119]
RACK1 TTJ10AL Limited Biomarker [120]
RECK TTRZBW7 Limited Posttranslational Modification [121]
ROBO1 TTND1YP Limited Altered Expression [122]
ROS1 TTSZ6Y3 Limited Biomarker [123]
RUNX3 TTKCVO7 Limited Genetic Variation [124]
S100A9 TT0TMQG Limited Altered Expression [125]
SAA1 TTY0DN9 Limited Biomarker [126]
SDC2 TT5H2F0 Limited Altered Expression [127]
SERPINB5 TT1KW50 Limited Altered Expression [128]
SLC22A1 TTM5Q4V Limited Genetic Variation [129]
SLC22A3 TTG2UMS Limited Altered Expression [130]
SLC2A4 TTP6MT5 Limited Altered Expression [131]
SOD2 TT9O4C5 Limited Biomarker [132]
SPHK1 TTOHFIY Limited Biomarker [133]
SREBF1 TTER0UB Limited Altered Expression [134]
TCF7L2 TT80QAL Limited Genetic Variation [135]
TNF TTF8CQI Limited Biomarker [136]
TNFSF14 TTKVENM Limited Biomarker [137]
TOP1 TTGTQHC Limited Biomarker [138]
TP53BP1 TTX4UE9 Limited Biomarker [81]
TPT1 TT3PTB6 Limited Altered Expression [139]
TXNRD1 TTR7UJ3 Limited Altered Expression [140]
USP7 TTXU3EQ Limited Biomarker [141]
WNK1 TTJ9UMX Limited Altered Expression [136]
XPA TTGT87E Limited Altered Expression [142]
ACAT1 TTK3C21 Disputed Altered Expression [143]
ARSA TTYQANR Disputed Biomarker [144]
CA2 TTANPDJ Disputed Genetic Variation [145]
CEACAM6 TTIGH2W Disputed Biomarker [146]
CFLAR TTJZQYH Disputed Altered Expression [147]
DYRK1B TTYGQ8A Disputed Altered Expression [148]
F2R TTL935N Disputed Biomarker [149]
FUT4 TTNV1KZ Disputed Altered Expression [150]
GLI2 TT045OH Disputed Biomarker [151]
IRS1 TTAJSQ0 Disputed Altered Expression [152]
PLA2G2A TTO8QRU Disputed Biomarker [153]
PTK7 TTXH2ZN Disputed Altered Expression [154]
SELE TT1PL7M Disputed Biomarker [150]
SOCS3 TTI0ME6 Disputed Biomarker [155]
ACLY TT0Z6Y2 moderate Biomarker [156]
ACVR2A TTX2DRI moderate Biomarker [157]
ADAM17 TT6AZXG moderate Biomarker [158]
ALKBH5 TTOHB1M moderate Biomarker [159]
ATXN3 TT6A17J moderate Altered Expression [160]
AURKA TTPS3C0 moderate Altered Expression [161]
BRD4 TTSRAOU moderate Altered Expression [162]
CAD TT2YT1K moderate Altered Expression [163]
CASP6 TTKW4ML moderate Biomarker [164]
CD24 TTCTYNP moderate Biomarker [165]
CDK1 TTH6V3D moderate Biomarker [166]
CHEK1 TTTU902 moderate Biomarker [167]
CLU TTRL76H moderate Biomarker [168]
CRP TTWRN6M moderate Genetic Variation [169]
DCLK1 TTOHTCY moderate Altered Expression [170]
DKK1 TTE3RAC moderate Biomarker [171]
EHMT2 TTS6RZT moderate Altered Expression [172]
ELAVL1 TTPC9D0 moderate Altered Expression [173]
EPAS1 TTWPA54 moderate Biomarker [174]
ERN1 TTKIAT3 moderate Biomarker [175]
F11R TT3C8EG moderate Biomarker [176]
F5 TT1O264 moderate Biomarker [177]
FOXM1 TTD3KOX moderate Biomarker [178]
FOXP3 TT1X3QF moderate Biomarker [179]
FTH1 TT975ZT moderate Biomarker [180]
GDF15 TT4MXVG moderate Biomarker [181]
HDAC9 TT8M4E1 moderate Biomarker [182]
HK2 TTK02H8 moderate Biomarker [183]
HMGA1 TTBA219 moderate Biomarker [184]
HMGCS1 TTQF4TK moderate Biomarker [185]
HMGCS2 TTS0EZJ moderate Biomarker [186]
HPGDS TTCYE56 moderate Biomarker [187]
HSF1 TTN6STZ moderate Biomarker [188]
HSPB3 TTLH8WG moderate Biomarker [189]
IFNB1 TT4TZ8J moderate Biomarker [190]
IL15 TTJFA35 moderate Biomarker [191]
INHBA TTVB30D moderate Biomarker [192]
ISG15 TTVOH3T moderate Biomarker [193]
ITGB8 TTIF29E moderate Biomarker [194]
MAP3K11 TTETX6Q moderate Genetic Variation [195]
MAP3K8 TTGECUM moderate Biomarker [196]
MAPK12 TTYT93M moderate Genetic Variation [197]
MBP TT2RY5P moderate Biomarker [198]
MDM4 TT9OUDQ moderate Biomarker [199]
MKNK1 TTEZAUX moderate Biomarker [200]
MTM1 TTY2TCU moderate Genetic Variation [201]
MYBPC3 TT9WOBN moderate Biomarker [180]
NME1 TTDY8JH moderate Altered Expression [202]
NR0B1 TTTK36V moderate Biomarker [203]
NR1I2 TT7LCTF moderate Biomarker [204]
NR4A1 TTMXE2Q moderate Biomarker [205]
OSMR TTAH0KM moderate Posttranslational Modification [206]
PIM3 TTCGOIN moderate Biomarker [207]
PLA2G7 TTDNFMT moderate Altered Expression [208]
PLD2 TTRLMKF moderate Altered Expression [209]
PRDX5 TTLPJWH moderate Biomarker [210]
PRKCA TTFJ8Q1 moderate Biomarker [211]
PRKCB TTYPXQF moderate Biomarker [212]
PRKCI TTWJTHX moderate Altered Expression [213]
PRKCZ TTBSN0L moderate Biomarker [214]
PRMT1 TTVOJAI moderate Altered Expression [215]
PTBP1 TTWMX0U moderate Altered Expression [216]
PTPN6 TT369M5 moderate Posttranslational Modification [217]
RAC1 TT2M9CG moderate Altered Expression [218]
RNF43 TTD91BL moderate Genetic Variation [219]
RPL15 TTQRVC9 moderate Biomarker [220]
RPS6KA1 TTIXKA4 moderate Altered Expression [221]
RPS6KA2 TT0ZW9O moderate Altered Expression [221]
RPS6KA3 TTUM2ZR moderate Altered Expression [221]
RRM2 TT1S4LJ moderate Altered Expression [222]
SATB1 TTLFRIC moderate Biomarker [223]
SIRT6 TTUXYWF moderate Biomarker [214]
SMAD3 TTHQZV7 moderate Genetic Variation [224]
SMAD7 TT0J32Z moderate Genetic Variation [225]
SPARC TTBQFM7 moderate Biomarker [226]
STAT1 TTN7R6K moderate Altered Expression [227]
SUV39H1 TTUWQTK moderate Altered Expression [228]
TGFA TTTLQFR moderate Biomarker [229]
TGFB2 TTI0KH6 moderate Altered Expression [230]
THBS1 TTKI0H1 moderate Biomarker [231]
TRPC5 TT32NQ1 moderate Biomarker [232]
TRPM7 TTFPVZO moderate Biomarker [233]
TWIST1 TTX1MY7 moderate Altered Expression [234]
TYMP TTO0IB8 moderate Biomarker [235]
VDAC3 TTT48SQ moderate Altered Expression [236]
XIAP TTK3WBU moderate Altered Expression [237]
XRCC5 TTCB9KW moderate Altered Expression [238]
ABCC1 TTOI92F Strong Genetic Variation [239]
ABCG2 TTIMJ02 Strong Biomarker [240]
ACKR3 TTRQJTC Strong Biomarker [241]
ACR TTAHE2N Strong Biomarker [242]
ADAM10 TTVXEGU Strong Biomarker [243]
ADAM9 TTTYQNS Strong Biomarker [244]
ADCYAP1 TTW4LYC Strong Biomarker [245]
ADCYAP1R1 TT5OREU Strong Biomarker [245]
ADIPOQ TTXKA7D Strong Biomarker [246]
ADM TTV14YH Strong Biomarker [247]
ADRA1A TTNGILX Strong Biomarker [241]
ADRA2B TTWM4TY Strong Biomarker [241]
AGR2 TT9K86S Strong Altered Expression [248]
AHCY TTE2KUJ Strong Altered Expression [249]
AHSG TTKF4WV Strong Biomarker [250]
AIMP2 TTXWHGF Strong Biomarker [251]
AKR1C3 TT5ZWB6 Strong Biomarker [252]
AKT2 TTH24WI Strong Biomarker [183]
ALCAM TT2AFT6 Strong Altered Expression [253]
ALOX15 TTN9T81 Strong Altered Expression [254]
ANG TTURHFP Strong Biomarker [255]
ANGPT1 TTWNQ1T Strong Biomarker [256]
ANGPTL4 TTWALY5 Strong Altered Expression [257]
ANO1 TTOJI4S Strong Biomarker [258]
ANXA5 TT2Z83I Strong Biomarker [259]
APC2 TTSMK36 Strong Altered Expression [260]
APEX1 TTHGL48 Strong Genetic Variation [261]
ARG1 TT7ZQEV Strong Altered Expression [262]
ASAP3 TTB4ZEN Strong Biomarker [263]
ASPH TT2KHP7 Strong Altered Expression [264]
ASRGL1 TT4WT91 Strong Altered Expression [265]
ATAT1 TTWUHQ1 Strong Altered Expression [266]
ATF3 TTCE793 Strong Altered Expression [267]
ATP2A2 TTE6THL Strong Genetic Variation [268]
ATR TT8ZYBQ Strong Genetic Variation [269]
ATXN2 TTPQJ7P Strong Genetic Variation [225]
AURKB TT9RTBL Strong Genetic Variation [270]
AZGP1 TTUPYLV Strong Biomarker [271]
B2M TTY7FKA Strong Genetic Variation [272]
BACE2 TT69DB8 Strong Altered Expression [273]
BACH1 TT2ME4S Strong Altered Expression [274]
BAK1 TTFM7V0 Strong Biomarker [275]
BAP1 TT47RXJ Strong Biomarker [276]
BBC3 TT7JUKC Strong Biomarker [277]
BCL2 TTFOUV4 Strong Altered Expression [278]
BCL2A1 TTGT9C7 Strong Biomarker [279]
BCL2L2 TTQ79W8 Strong Biomarker [280]
BECN1 TT5M7LN Strong Biomarker [281]
BIRC5 TTTPU1G Strong Biomarker [282]
BIRC7 TTHZ8TA Strong Biomarker [283]
BMP1 TT0L58T Strong Biomarker [163]
BMP2 TTP3IGX Strong Altered Expression [284]
BMP4 TTD3BSX Strong Genetic Variation [224]
BMP7 TTKOBRA Strong Biomarker [285]
BMPR2 TTGKF90 Strong Genetic Variation [286]
BRCA2 TTUARD6 Strong Biomarker [287]
BRS3 TTKYEPM Strong Biomarker [241]
BTG1 TTL7N2W Strong Biomarker [288]
BTK TTGM6VW Strong Biomarker [289]
C1QBP TTWTD7F Strong Altered Expression [290]
C5AR1 TTHXFA1 Strong Biomarker [291]
CA13 TTQPHSR Strong Biomarker [292]
CA4 TTZHA0O Strong Biomarker [293]
CACNA2D1 TTFK1JQ Strong Biomarker [294]
CALR TTUZ7OA Strong Altered Expression [295]
CAMP TTULOB6 Strong Biomarker [296]
CASP10 TTX5HEK Strong Genetic Variation [297]
CASP7 TTM7Y45 Strong Altered Expression [298]
CASR TTBUYHA Strong Genetic Variation [299]
CBR1 TTVG0SN Strong Altered Expression [300]
CBS TTVZJ7G Strong Biomarker [301]
CBX7 TTBN3HC Strong Altered Expression [302]
CCK TT90CMU Strong Biomarker [303]
CCKAR TTCG0AL Strong Biomarker [304]
CCL17 TTMPHAE Strong Biomarker [305]
CCL20 TT2XAZY Strong Biomarker [294]
CCL21 TTLZK1U Strong Biomarker [306]
CCL3 TT8I4WB Strong Biomarker [307]
CCNA2 TTAMQ62 Strong Altered Expression [308]
CCNB1 TT9P6OW Strong Altered Expression [309]
CCNE2 TTLDRGX Strong Biomarker [310]
CCR1 TTC24WT Strong Biomarker [311]
CCR7 TT2GIDQ Strong Altered Expression [312]
CD248 TTYJWT7 Strong Altered Expression [313]
CD274 TT8ZLTI Strong Biomarker [314]
CD80 TT89Z17 Strong Biomarker [315]
CD9 TTZEIBV Strong Altered Expression [316]
CDC25A TTLZS4Q Strong Biomarker [317]
CDC37 TT5SOEU Strong Genetic Variation [318]
CDC42BPA TT5Z0EF Strong Altered Expression [319]
CDH11 TTRGWZC Strong Biomarker [320]
CDH3 TTARMD9 Strong Genetic Variation [224]
CDK2 TT7HF4W Strong Altered Expression [321]
CDK5 TTL4Q97 Strong Biomarker [322]
CDK6 TTO0FDJ Strong Biomarker [323]
CDK9 TT1LVF2 Strong Biomarker [324]
CEACAM1 TTA9CK4 Strong Biomarker [325]
CHAT TTKYFSB Strong Biomarker [326]
CHKA TT10AWB Strong Biomarker [327]
CHM TTOA18V Strong Biomarker [328]
CHRM3 TTQ13Z5 Strong Biomarker [329]
CIT TT3BKTU Strong Altered Expression [330]
CLCA1 TT3AF4R Strong Biomarker [331]
CLIC1 TT8KZG6 Strong Biomarker [332]
CLN3 TTORF9W Strong Altered Expression [333]
COL1A2 TTUABC1 Strong Altered Expression [163]
COPS5 TTSTNJR Strong Altered Expression [334]
CRAT TTC8M31 Strong Biomarker [335]
CRK TTFEUYR Strong Biomarker [251]
CRY2 TTAO58M Strong Altered Expression [336]
CRYAB TT7RUHB Strong Biomarker [294]
CSK TTX6F0Q Strong Biomarker [337]
CSNK1A1 TTFQEMX Strong Biomarker [338]
CSNK2A1 TTER6YH Strong Biomarker [339]
CTCFL TTY0RZT Strong Biomarker [340]
CTH TTLQUZS Strong Altered Expression [341]
CTSE TTLXC4Q Strong Altered Expression [342]
CUBN TT9YLCR Strong Genetic Variation [343]
CXCL10 TTQOVYA Strong Biomarker [294]
CXCL12 TT4UGTF Strong Biomarker [344]
CXCL13 TT0NIZ1 Strong Biomarker [345]
CXCR2 TT30C9G Strong Altered Expression [346]
CXCR4 TTBID49 Strong Altered Expression [347]
CXCR5 TTIW59R Strong Biomarker [345]
CXCR6 TT2BVUA Strong Biomarker [241]
CYP17A1 TTRA5BZ Strong Genetic Variation [348]
CYP2A6 TTAQ6ZW Strong Genetic Variation [349]
CYP2E1 TTWVHQ5 Strong Therapeutic [350]
CYSLTR1 TTGKOY9 Strong Biomarker [351]
CYSLTR2 TT0PZR5 Strong Biomarker [352]
DAG1 TT4X7PG Strong Altered Expression [353]
DDX58 TTVB0O3 Strong Biomarker [354]
DEFB4A TTIVY12 Strong Altered Expression [355]
DEK TT1NMGV Strong Altered Expression [356]
DHCR24 TTTK0NH Strong Biomarker [357]
DHFR TTYZVDJ Strong Biomarker [358]
DIABLO TTN74LE Strong Biomarker [359]
DLL1 TT9CFQD Strong Genetic Variation [360]
DLL4 TTV23LH Strong Biomarker [361]
DNASE1 TTYWGOJ Strong Biomarker [362]
DPP4 TTDIGC1 Strong Biomarker [363]
DPYD TTZPS91 Strong Biomarker [364]
DTL TT8396I Strong Altered Expression [365]
DUSP10 TTF3RJ0 Strong Altered Expression [366]
E2F1 TTASI04 Strong Altered Expression [367]
EBP TT4VQZX Strong Biomarker [368]
EDN2 TTMR0OP Strong Posttranslational Modification [369]
EEF2K TT1QFLA Strong Altered Expression [370]
EGF TTED8JB Strong Biomarker [371]
EGLN1 TT9ISBX Strong Altered Expression [136]
EIF4EBP1 TTKGEBL Strong Biomarker [372]
EIF5A TTIVCNR Strong Biomarker [373]
ENPP3 TTD4TKP Strong Biomarker [374]
EPCAM TTZ8WH4 Strong Altered Expression [375]
EPHA1 TTLFZVU Strong Altered Expression [376]
EPHA2 TTRJB2G Strong Altered Expression [376]
EPHA3 TTHS2LR Strong Altered Expression [377]
EPHA5 TTV9KOD Strong Genetic Variation [378]
EPHA8 TTHZ2LW Strong Altered Expression [379]
EPHB2 TTKPV6O Strong Biomarker [380]
EPHB4 TTI4ZX2 Strong Altered Expression [381]
EPX TTCIO0M Strong Genetic Variation [382]
ERAP1 TT60XFL Strong Genetic Variation [343]
ERBB3 TTSINU2 Strong Biomarker [383]
ETS2 TT9AH0M Strong Biomarker [384]
F2RL3 TTD0652 Strong Altered Expression [385]
F3 TT38MDJ Strong Biomarker [386]
F7 TTF0EGX Strong Biomarker [386]
FABP1 TTIV96N Strong Altered Expression [341]
FADS2 TTT2VDU Strong Genetic Variation [225]
FAP TTGPQ0F Strong Biomarker [387]
FBXO11 TT6G10V Strong CausalMutation [388]
FCGR3A TTIFOC0 Strong Genetic Variation [389]
FCGRT TTKLPHO Strong Biomarker [390]
FDXR TT3W4IX Strong Biomarker [391]
FECH TTQ6VF4 Strong Biomarker [392]
FFAR1 TTB8FUC Strong Biomarker [393]
FFAR2 TT0FYAN Strong Biomarker [394]
FGF1 TTMY81X Strong Biomarker [76]
FGF19 TTGCH11 Strong Altered Expression [395]
FGF4 TTCEKVZ Strong Altered Expression [396]
FGF7 TTFY134 Strong Biomarker [397]
FHL1 TTI7ENL Strong Posttranslational Modification [398]
FKBP5 TT0J5KQ Strong Genetic Variation [224]
FOSL2 TT689IR Strong Biomarker [399]
FOXO1 TTLRVIA Strong Biomarker [400]
FPR2 TTOJ1NF Strong Biomarker [401]
FPR3 TT16TM5 Strong Altered Expression [402]
FSHR TTZFDBT Strong Biomarker [403]
FZD10 TTP1S2F Strong Altered Expression [404]
FZD7 TTUQMO5 Strong Altered Expression [405]
G3BP1 TTG0R8Z Strong Altered Expression [406]
GALR2 TTBPW3J Strong Biomarker [407]
GAP43 TTSGLN5 Strong Biomarker [294]
GATA3 TT45KOB Strong Genetic Variation [408]
GCGR TT9O6WS Strong Biomarker [409]
GCLM TTNFESW Strong Altered Expression [410]
GHR TTHJWYD Strong Biomarker [411]
GHSR TTWDC17 Strong Biomarker [412]
GLI1 TTJOMH6 Strong Biomarker [413]
GLO1 TTV9A7R Strong Biomarker [414]
GMNN TT390KA Strong Altered Expression [415]
GNAO1 TTAXD8Z Strong Biomarker [416]
GPI TT19JIZ Strong Biomarker [417]
GPR137 TTATO6X Strong Biomarker [418]
GPR35 TT254XD Strong Altered Expression [419]
GPR55 TTNET8J Strong Biomarker [420]
GREM1 TTOUZN5 Strong Biomarker [421]
GRM3 TT8A9EF Strong Biomarker [422]
GSN TTUH7OM Strong Biomarker [423]
GSS TTVEWR4 Strong Altered Expression [424]
GSTO1 TTWO3SH Strong Biomarker [425]
GUSB TTHS7CM Strong Altered Expression [426]
GZMB TTKEPHX Strong Altered Expression [427]
HCK TT42OGM Strong Biomarker [428]
HCRTR1 TT60Q8D Strong Altered Expression [429]
HDAC10 TTYHPU6 Strong Biomarker [430]
HDAC3 TT4YWTO Strong Biomarker [431]
HDAC6 TT5ZKDI Strong Altered Expression [432]
HDC TTV9GOF Strong Biomarker [433]
HDGF TTKGV26 Strong Altered Expression [434]
HEXB TTKIBKM Strong Genetic Variation [435]
HGF TT4V2JM Strong Biomarker [436]
HIPK2 TTOB49C Strong Biomarker [437]
HLA-G TTLKFB3 Strong Altered Expression [438]
HMGB1 TTWQYB7 Strong Altered Expression [439]
HMGCR TTPADOQ Strong Genetic Variation [440]
HNF4A TT2F3CD Strong Altered Expression [441]
HNRNPA1 TTPJ9XK Strong Biomarker [442]
HOXA5 TTXSVQP Strong Altered Expression [443]
HPSE TTR7GJO Strong Biomarker [444]
HSD11B2 TT9H85R Strong Altered Expression [445]
HSD17B4 TTL1WGS Strong Biomarker [446]
HSP90AA1 TT78R5H Strong Biomarker [447]
HSP90B1 TTFPKXQ Strong Altered Expression [448]
HSPA5 TTW26OG Strong Altered Expression [449]
HSPA8 TTMQL3K Strong Biomarker [450]
HSPB1 TT9AZWY Strong Biomarker [189]
ICOS TTE5VP6 Strong Biomarker [451]
ICOSLG TTB9Z8R Strong Biomarker [452]
IDUA TT0IUKX Strong Biomarker [453]
IFNG TT93WF5 Strong Altered Expression [88]
IGFBP1 TTCJTWF Strong Biomarker [294]
IGFBP2 TTU4QSN Strong Biomarker [454]
IGFBP3 TTZHNQA Strong Genetic Variation [455]
IGFBP5 TTDWEA8 Strong Altered Expression [456]
IKBKB TTJ3E9X Strong Biomarker [457]
IL15RA TTGN89I Strong Biomarker [191]
IL17A TTG0MT6 Strong Biomarker [458]
IL17F TT2B6PS Strong Genetic Variation [459]
IL1R1 TTWOTEA Strong Altered Expression [460]
IL1R2 TT51DEV Strong Altered Expression [461]
IL21 TT9QEJ6 Strong Altered Expression [462]
IL23R TT6H4QR Strong Biomarker [459]
IL24 TT1EPXZ Strong Biomarker [463]
IL32 TTD4G7L Strong Biomarker [464]
INPP5D TTTP2Z1 Strong Biomarker [465]
IRF8 TTHUBNK Strong Biomarker [466]
ITGA4 TTJMF9P Strong Biomarker [467]
ITGA5 TTHIZP9 Strong Altered Expression [468]
ITGB3 TTJA1ZO Strong Biomarker [469]
ITGB6 TTKQSXZ Strong Biomarker [470]
JAG2 TTOJY1B Strong Biomarker [471]
JAK1 TT6DM01 Strong Altered Expression [472]
JMJD1C TTBISK4 Strong Biomarker [473]
KCNA5 TTW0CMT Strong Biomarker [474]
KCND3 TTPLQO0 Strong Biomarker [475]
KCNH1 TT9XKUC Strong Genetic Variation [476]
KCNH2 TTQ6VDM Strong Biomarker [477]
KDM1A TTNR0UQ Strong Biomarker [478]
KDM3A TTKXS4A Strong Altered Expression [479]
KDM4A TTZHPB8 Strong Biomarker [480]
KDM5B TTCLI75 Strong Biomarker [478]
KDM5C TT94UCF Strong Altered Expression [481]
KISS1R TT3KBZY Strong Altered Expression [482]
KLF4 TTTI53X Strong Biomarker [439]
KLK14 TTDA81R Strong Altered Expression [483]
KLK2 TTJLNAW Strong Biomarker [474]
KLK6 TTLPF4X Strong Biomarker [484]
KLK7 TTE6GTB Strong Altered Expression [483]
KLRK1 TTLRN4A Strong Biomarker [485]
LAPTM4B TTEJQT0 Strong Biomarker [486]
LCK TT860QF Strong Altered Expression [487]
LCN2 TTKTLAI Strong Biomarker [488]
LDLR TTH0DUS Strong Biomarker [180]
LGR5 TTTSGRH Strong Altered Expression [489]
LIF TTGZ5WN Strong Biomarker [490]
LIFR TTID542 Strong Altered Expression [491]
LILRB1 TTC0QRJ Strong Altered Expression [117]
LIMK1 TTWL9TY Strong Biomarker [492]
LIN28A TTO50LN Strong Genetic Variation [493]
LNPEP TTY2KP7 Strong Biomarker [494]
LOX TTQHNAM Strong Biomarker [495]
LOXL2 TTFSUHX Strong Biomarker [496]
LPA TTU9LGY Strong Biomarker [497]
LPAR1 TTQ6S1K Strong Genetic Variation [224]
LPAR2 TTB7Y8I Strong Biomarker [241]
LPAR3 TTE2YJR Strong Biomarker [498]
LPL TTOF3WZ Strong Biomarker [294]
LRP1 TTF2V7I Strong Genetic Variation [224]
LRRC32 TT0FAYT Strong Genetic Variation [499]
LTB4R TTN53ZF Strong Biomarker [500]
MAD1L1 TTNE9U7 Strong Altered Expression [501]
MAOB TTGP7BY Strong Biomarker [294]
MAP2K1 TTIDAPM Strong Genetic Variation [502]
MAP2K5 TTV3O87 Strong Biomarker [101]
MAP2K7 TT6QY3J Strong Biomarker [185]
MAP3K10 TT9FN4J Strong Biomarker [301]
MAP3K20 TTTUZ3O Strong Biomarker [503]
MAP3K21 TTSW9YL Strong Biomarker [504]
MAP3K5 TTOQCD8 Strong Biomarker [505]
MAPK14 TTQBR95 Strong Biomarker [251]
MAPK3 TT1MG9E Strong Biomarker [221]
MAPK8 TT0K6EO Strong Biomarker [506]
MAPK9 TT3IVG2 Strong Altered Expression [507]
MARCKS TTHRM39 Strong Biomarker [508]
MARK2 TTAJ45Y Strong Biomarker [509]
MAT2A TTSMPXQ Strong Biomarker [510]
MAZ TT059DA Strong Altered Expression [511]
MBTPS1 TTNSM2I Strong Altered Expression [512]
MC4R TTD0CIQ Strong Altered Expression [513]
MDM2 TT9TE0O Strong Biomarker [514]
MGLL TTZ963I Strong Biomarker [515]
MKI67 TTB4UNG Strong Biomarker [516]
MMP12 TTXZ0KQ Strong Biomarker [294]
MMP2 TTLM12X Strong Biomarker [193]
MMP3 TTUZ2L5 Strong Altered Expression [517]
MRC1 TTKV8W5 Strong Genetic Variation [518]
MSI2 TTTXQF6 Strong Biomarker [519]
MST1R TTBQ3OC Strong Altered Expression [520]
MTOR TTCJG29 Strong Biomarker [81]
MTR TTUTO39 Strong Genetic Variation [521]
MUC15 TTGQ6MI Strong Biomarker [522]
MUC5AC TTEL90S Strong Biomarker [523]
MUTYH TTNB0ZK Strong Genetic Variation [524]
MYB TT8V13P Strong Genetic Variation [525]
MYCBP TTVW4XU Strong Altered Expression [526]
MYLK TT18ETS Strong Altered Expression [527]
NAPEPLD TTFMCB6 Strong Biomarker [420]
NCF1 TTZ4JC3 Strong Biomarker [528]
NCL TTK1V5Q Strong Biomarker [529]
NCOA4 TT8OY02 Strong Genetic Variation [530]
NECTIN4 TTPO9EG Strong Biomarker [531]
NEDD8 TTNDC4K Strong Biomarker [532]
NEK8 TT8AH9I Strong Biomarker [533]
NFKB1 TTUIZKC Strong Genetic Variation [534]
NFKB2 TTKLNRV Strong Altered Expression [535]
NLRP1 TTQX29T Strong Biomarker [536]
NLRX1 TTKT026 Strong Biomarker [537]
NME9 TTHSVK0 Strong Altered Expression [538]
NOTCH1 TTB1STW Strong Biomarker [539]
NOTCH4 TTXDIK2 Strong Genetic Variation [135]
NOX4 TTQRBSJ Strong Biomarker [540]
NPSR1 TTV1C0Z Strong Genetic Variation [541]
NQO1 TT8XK6L Strong Altered Expression [542]
NR0B2 TT25A9Q Strong Altered Expression [543]
NR1H2 TTXA6PH Strong Biomarker [544]
NR4A2 TT9HKN3 Strong Biomarker [545]
NR5A2 TTAU3SY Strong Altered Expression [546]
NRP2 TTRXUVC Strong Altered Expression [547]
NTF4 TTIM2WO Strong Biomarker [548]
NTN1 TT0AH4L Strong Genetic Variation [549]
NUAK1 TT65FL0 Strong Altered Expression [550]
NUF2 TTIXBFP Strong Biomarker [551]
ODC1 TTUMGNO Strong Biomarker [552]
OLR1 TTKSND3 Strong Biomarker [553]
ORAI1 TTE76YK Strong Biomarker [554]
OSM TTIVXSE Strong Biomarker [555]
PADI3 TTSCHFW Strong Biomarker [556]
PAK4 TT7Y3BZ Strong Biomarker [557]
PAM TTF4ZPC Strong Biomarker [558]
PAWR TT3I4WV Strong Biomarker [559]
PBRM1 TTH8ZRL Strong Biomarker [560]
PCSK9 TTNIZ2B Strong Biomarker [561]
PCYT1B TTUAIKM Strong Biomarker [562]
PDCD1 TTNBFWK Strong Biomarker [563]
PDE4B TTVIAT9 Strong Altered Expression [564]
PDE5A TTJ0IQB Strong Altered Expression [565]
PDK1 TTCZOF2 Strong Biomarker [566]
PDXP TT9UYG4 Strong Genetic Variation [567]
PF4 TTSG7Q5 Strong Biomarker [59]
PFKFB3 TTTHMQJ Strong Biomarker [568]
PGGT1B TTX20QP Strong Biomarker [569]
PHLDB3 TT1KS9D Strong Biomarker [570]
PIGU TT2LHI6 Strong Genetic Variation [224]
PIK3CB TT9H4P3 Strong Biomarker [571]
PINX1 TT4FJ3A Strong Biomarker [572]
PIP5K1A TTA7DU1 Strong Biomarker [573]
PKM TT4LOT8 Strong Altered Expression [236]
PKN2 TTTHO0M Strong Altered Expression [574]
PLA2G4A TTT1JVS Strong Biomarker [575]
PLAUR TTNOSTX Strong Biomarker [576]
PLCB1 TTLPGU7 Strong Biomarker [294]
PLCG1 TT6T4JI Strong Biomarker [577]
PLK1 TTH4IP0 Strong Altered Expression [578]
PLK4 TTGPNZQ Strong Biomarker [579]
PMEL TT8MK59 Strong Altered Expression [535]
PNKP TTHR3IE Strong Altered Expression [238]
PNP TTMCF1Y Strong Biomarker [580]
POLB TTA0XPV Strong Biomarker [581]
PPARD TT2JWF6 Strong Biomarker [582]
PPARG TTT2SVW Strong Biomarker [583]
PPARGC1B TTKSQ3W Strong Biomarker [584]
PPIB TT6ZFQ4 Strong Biomarker [585]
PPID TTNAFOU Strong Biomarker [586]
PPIF TTRFQTB Strong Biomarker [586]
PPM1D TTENJAB Strong Biomarker [587]
PPOX TTNFMS9 Strong Biomarker [588]
PREP TTNGKET Strong Biomarker [589]
PRKAR1A TTNAHEX Strong Genetic Variation [590]
PRKD1 TTSLUMT Strong Biomarker [591]
PRKDC TTK3PY9 Strong Biomarker [592]
PRKG1 TT7IZSA Strong Biomarker [593]
PRKG2 TTDWFCQ Strong Altered Expression [594]
PRMT5 TTR1D7X Strong Altered Expression [595]
PROKR1 TTB9CIL Strong Altered Expression [596]
PROKR2 TTM67AX Strong Biomarker [596]
PRSS1 TT2WR1T Strong Altered Expression [597]
PSMB6 TT8EPLT Strong Genetic Variation [360]
PSMB8 TTEAD9J Strong Genetic Variation [598]
PSMD10 TT2H4LN Strong Biomarker [599]
PTGER3 TTPNGDE Strong Biomarker [600]
PTGES TTYLQ8V Strong Altered Expression [601]
PTGIS TTLXKZR Strong Biomarker [602]
PTP4A3 TT7YM8D Strong Altered Expression [603]
PTPN1 TTELIN2 Strong Biomarker [604]
PTPN13 TT405FP Strong Biomarker [605]
PYY TTVFJLX Strong Biomarker [606]
RAB22A TTAJ746 Strong Biomarker [607]
RAC3 TT9BQ50 Strong Altered Expression [608]
RALBP1 TTVSRUA Strong Biomarker [609]
RASA1 TTPNZ1F Strong Altered Expression [610]
REG3A TTL4H8N Strong Biomarker [245]
REG4 TTVZEHU Strong Altered Expression [611]
RENBP TTZCG0Q Strong Genetic Variation [612]
RIPK1 TTVJHX8 Strong Altered Expression [613]
RNASEL TT7V0K4 Strong Genetic Variation [614]
RNF34 TTEWDK1 Strong Therapeutic [615]
ROR1 TTDEJAU Strong Altered Expression [616]
RPS6KB1 TTG0U4H Strong Altered Expression [617]
RRM1 TTWP0NS Strong Biomarker [618]
RSF1 TTMP86V Strong Biomarker [619]
RSPO1 TTI9HL4 Strong Biomarker [620]
RUNX2 TTD6SZ8 Strong Biomarker [621]
RXRA TT6PEUO Strong Biomarker [622]
RXRG TTH029C Strong Biomarker [623]
S100A4 TTPR5SX Strong Altered Expression [624]
S100A6 TT716MY Strong Biomarker [625]
SCD TT6RIOV Strong Biomarker [626]
SCN5A TTZOVE0 Strong Biomarker [627]
SDC1 TTYDSVG Strong Biomarker [628]
SELL TT2IYXF Strong Biomarker [629]
SEMA4D TT5UT28 Strong Biomarker [630]
SENP1 TTW9HY5 Strong Biomarker [631]
SERPINB3 TT6QLPX Strong Biomarker [632]
SETD2 TTPC3H4 Strong Altered Expression [633]
SFRP4 TTX8I1Y Strong Genetic Variation [634]
SGO1 TTBPKGD Strong Biomarker [635]
SGPL1 TT618Q2 Strong Biomarker [636]
SH2B3 TT36N7Z Strong Genetic Variation [225]
SHCBP1 TTZ9WGL Strong Biomarker [558]
SIRT2 TTLKF5M Strong Biomarker [637]
SIRT3 TTVZLIJ Strong Altered Expression [638]
SLC10A2 TTPI1M5 Strong Biomarker [639]
SLC12A3 TTP362L Strong Biomarker [640]
SLC12A5 TTH6UZY Strong Genetic Variation [641]
SLC16A1 TTN1J82 Strong Biomarker [642]
SLC17A5 TTFSUIA Strong Biomarker [643]
SLC19A1 TT09I7D Strong Biomarker [644]
SLC19A3 TT9BTWM Strong Posttranslational Modification [645]
SLC1A2 TT2F078 Strong Biomarker [646]
SLC1A5 TTF7WRM Strong Biomarker [647]
SLC22A16 TTITAVR Strong Genetic Variation [648]
SLC23A2 TTOP832 Strong Altered Expression [649]
SLC29A1 TTLXAKE Strong Altered Expression [650]
SLC2A1 TT79TKF Strong Altered Expression [383]
SLC3A2 TT5CZSM Strong Biomarker [651]
SLC5A5 TTW7HI9 Strong Biomarker [652]
SLC7A1 TT4S150 Strong Biomarker [335]
SLC7A5 TTPH2JB Strong Biomarker [651]
SLCO1B1 TTFGXEB Strong Altered Expression [653]
SLCO2A1 TTKVTQO Strong Genetic Variation [135]
SLK TT8K4DE Strong Biomarker [654]
SMAD6 TTON5JB Strong Genetic Variation [224]
SMAD9 TTX8EBV Strong Genetic Variation [224]
SMPD1 TTJTM88 Strong Biomarker [655]
SMYD2 TT7YJFO Strong Biomarker [656]
SNCG TT5TQNZ Strong Biomarker [657]
SOCS1 TT8COJM Strong Biomarker [658]
SP1 TTZEP6S Strong Altered Expression [659]
SPDEF TT2ZUPY Strong Altered Expression [660]
SPHK2 TTCN0M9 Strong Altered Expression [661]
SPTBN1 TTS9BDA Strong Biomarker [662]
SRGN TTCHB06 Strong Biomarker [663]
SRPK1 TTU3WV6 Strong Biomarker [664]
SRPK2 TTCZEJ9 Strong Biomarker [665]
SST TTWF7UG Strong Biomarker [666]
SSTR1 TTIND6G Strong Biomarker [667]
SSTR2 TTZ6T9E Strong Biomarker [668]
SSTR4 TTAE1BR Strong Biomarker [241]
ST14 TTPRO7W Strong Altered Expression [669]
STAT6 TTWOE1T Strong Biomarker [670]
SYK TT2HUPM Strong Biomarker [671]
SYVN1 TT8XKYM Strong Biomarker [672]
TACSTD2 TTP2HE5 Strong Altered Expression [673]
TAGLN TTDRZ9H Strong Biomarker [294]
TDG TTEXRQD Strong Altered Expression [674]
TDP2 TTYF26D Strong Genetic Variation [675]
TERF2 TT5XSLT Strong Altered Expression [676]
TFAP2A TTDY4BS Strong Genetic Variation [677]
TFF1 TTNOJIZ Strong Altered Expression [678]
TFPI TT068JH Strong Genetic Variation [679]
TGFB3 TTWOMY8 Strong Biomarker [680]
TGFBR1 TTP4520 Strong Altered Expression [681]
TGFBR2 TTZE3P7 Strong Biomarker [682]
TIAM1 TTNU6I5 Strong Altered Expression [683]
TKT TT04R7I Strong Altered Expression [684]
TKTL1 TTNQ1J3 Strong Altered Expression [684]
TLR5 TTCXP8J Strong Altered Expression [685]
TLR6 TTWRI8V Strong Altered Expression [686]
TMEM97 TT9NXW4 Strong Altered Expression [687]
TMPRSS11D TTWHYC8 Strong Biomarker [688]
TNC TTUCPMY Strong Biomarker [689]
TNFRSF10A TT5WLRX Strong Altered Expression [690]
TNFRSF10B TTW20TU Strong Biomarker [690]
TNFRSF25 TTDV6BQ Strong Altered Expression [691]
TNFRSF8 TT2GM5R Strong Biomarker [692]
TNFRSF9 TTPW9LJ Strong Biomarker [693]
TNFSF10 TTA5MS9 Strong Biomarker [694]
TNFSF15 TTEST6I Strong Altered Expression [691]
TNIK TTPB1W3 Strong Biomarker [695]
TNKS TTVUSO7 Strong Biomarker [696]
TNS4 TT1K65C Strong Altered Expression [697]
TOP2A TTCGY2K Strong Biomarker [698]
TPBG TT70MLA Strong Biomarker [699]
TPX2 TT0PHL4 Strong Altered Expression [700]
TRIM27 TTTO3QN Strong Biomarker [401]
TRPC1 TTA76X0 Strong Altered Expression [554]
TRPC6 TTRBT3W Strong Genetic Variation [224]
TRPM6 TTV76RD Strong Altered Expression [701]
TRPV6 TTBK14N Strong Biomarker [335]
TXN TTZJ5U9 Strong Altered Expression [209]
TYRO3 TTIEMFN Strong Altered Expression [702]
TYRP1 TTFRV98 Strong Altered Expression [597]
UCHL5 TTSX29Z Strong Biomarker [703]
UCP2 TTSC2YM Strong Biomarker [704]
UGT1A1 TT34ZAF Strong Altered Expression [705]
UMPS TTAFJUD Strong Biomarker [235]
USP10 TT5IH09 Strong Biomarker [519]
USP14 TTVSYP9 Strong Biomarker [703]
UTRN TTNO1VA Strong Altered Expression [706]
UTS2R TTW5UDX Strong Altered Expression [707]
VANGL1 TT18WJB Strong Biomarker [708]
VDAC1 TTAMKGB Strong Biomarker [709]
VDAC2 TTM1I7L Strong Biomarker [709]
VDR TTK59TV Strong Altered Expression [710]
VEGFC TT0QUFV Strong Altered Expression [711]
VIPR1 TTCL30I Strong Altered Expression [712]
VSIR TT51SK8 Strong Biomarker [713]
WAS TTE8T73 Strong Biomarker [714]
WDR5 TT7OFWB Strong Altered Expression [715]
WEE1 TTJFOAL Strong Biomarker [716]
WNT5A TTKG7F8 Strong Biomarker [717]
WRN TT2H5WQ Strong Genetic Variation [658]
WT1 TTZ8UT4 Strong Biomarker [718]
YAP1 TT8UN2D Strong Biomarker [719]
YES1 TT0SQ8J Strong Altered Expression [720]
ZEB2 TTT2WK4 Strong Biomarker [721]
ZNF217 TTY3BRA Strong Biomarker [722]
CCR8 TTE836A Definitive Biomarker [723]
CDK8 TTBJR4L Definitive Biomarker [517]
COL18A1 TT63DI9 Definitive Biomarker [724]
CSE1L TTTRULD Definitive Altered Expression [725]
CXCL1 TTLK1RW Definitive Altered Expression [57]
DGKZ TTSBBXL Definitive Altered Expression [726]
GABRA1 TT1MPAY Definitive Altered Expression [727]
GRK3 TT5A4DX Definitive Biomarker [728]
HOXB13 TTZ6I58 Definitive Biomarker [729]
IL33 TT5MD4P Definitive Biomarker [730]
KLK4 TT4319X Definitive Altered Expression [483]
MAP3K7 TTJQT60 Definitive Biomarker [731]
MIA TT5HNVS Definitive Biomarker [732]
MSRB1 TT1QUZV Definitive Biomarker [733]
NOP2 TTBLG3H Definitive Altered Expression [610]
PCNA TTLG1PD Definitive Altered Expression [734]
PLOD1 TTEKJP3 Definitive Altered Expression [735]
PTPRJ TTWMKXP Definitive Genetic Variation [736]
SLCO1B3 TTU86P0 Definitive Biomarker [737]
TMSB4X TTMVAIU Definitive Altered Expression [738]
TNFRSF17 TTZ3P4W Definitive Biomarker [739]
------------------------------------------------------------------------------------
⏷ Show the Full List of 794 DTT(s)
This Disease Is Related to 21 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC2A2 DTUJPOL Limited Altered Expression [131]
SLC25A20 DTQOUM4 Disputed Genetic Variation [145]
SLC2A3 DT9SQ3L moderate Genetic Variation [740]
ABCB5 DTKVEXO Strong Biomarker [741]
ATP7A DT0LT17 Strong Biomarker [742]
SLC14A2 DT8QC7K Strong Altered Expression [707]
SLC16A12 DTZOKFJ Strong Biomarker [407]
SLC22A5 DT3HUVD Strong Biomarker [743]
SLC25A26 DT8HR5O Strong Genetic Variation [224]
SLC25A3 DTCRIWV Strong Biomarker [744]
SLC25A37 DTLBGTZ Strong Altered Expression [745]
SLC26A2 DTFSLX5 Strong Altered Expression [746]
SLC29A2 DTW78DQ Strong Altered Expression [650]
SLC2A5 DTOR02F Strong Biomarker [747]
SLC35A2 DT0567K Strong Altered Expression [748]
SLC44A1 DT3I2SU Strong Biomarker [336]
SLC4A2 DTF7GAL Strong Altered Expression [749]
SLC52A1 DT7NOKR Strong Biomarker [74]
SLC5A8 DTE3TAW Strong Altered Expression [85]
SLC6A18 DTGQ7FH Strong Genetic Variation [224]
SLCO6A1 DTIFXNS Strong Biomarker [750]
------------------------------------------------------------------------------------
⏷ Show the Full List of 21 DTP(s)
This Disease Is Related to 50 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
APRT DE2MV1R Limited Biomarker [751]
CYB5A DE9A2LB Limited Genetic Variation [752]
CYB5R3 DE4A3BL Limited Biomarker [752]
GCLC DESYL1F Limited Altered Expression [542]
ALDH1A1 DE2JP1Y Disputed Altered Expression [753]
NAT2 DER7TA0 Disputed Genetic Variation [754]
ACSS2 DEE76VW moderate Biomarker [755]
CMPK1 DEMPH4I moderate Altered Expression [756]
FADS1 DE05S8C moderate Altered Expression [757]
SULT1E1 DESTKG6 moderate Biomarker [196]
ADH1C DEM1HNL Strong Genetic Variation [758]
AKR1B10 DEP6GT1 Strong Altered Expression [759]
AKR1C1 DE7P2FB Strong Biomarker [252]
ALDH1B1 DEXI4UQ Strong Biomarker [760]
BAAT DERA3OF Strong Altered Expression [761]
CES2 DETHCPD Strong Biomarker [762]
CHDH DEAHED0 Strong Genetic Variation [763]
CRMP1 DE0EUXB Strong Altered Expression [706]
CYP27B1 DE3FYEM Strong Biomarker [764]
CYP2R1 DEBIHM3 Strong Genetic Variation [765]
CYP4F3 DEFCMPI Strong Genetic Variation [766]
CYP7A1 DEDZRQ1 Strong Genetic Variation [767]
CYP7B1 DE36TMY Strong Altered Expression [768]
DHCR7 DEL7GFA Strong Genetic Variation [765]
DTYMK DEOTVYU Strong Biomarker [769]
EGLN3 DEMQTKH Strong Genetic Variation [770]
FMO5 DEBMX7C Strong Altered Expression [771]
FPGS DECWT2V Strong Altered Expression [772]
GLS DE3E0VT Strong Biomarker [773]
GMDS DE8K7F3 Strong Genetic Variation [774]
GSTT1 DE3PKUG Strong Genetic Variation [775]
HPGD DEHKSC6 Strong Biomarker [776]
HPRT1 DEVXTP5 Strong Genetic Variation [777]
HSD17B7 DEDMWFX Strong Biomarker [778]
ME1 DE97WM8 Strong Biomarker [779]
MT2A DEFKGT7 Strong Altered Expression [780]
MTARC2 DE6QH2D Strong Biomarker [781]
MTRR DE6NIY9 Strong Genetic Variation [782]
NAT10 DEZV4AP Strong Altered Expression [265]
NT5C DE4E31Z Strong Altered Expression [783]
PARK7 DEPOVCH Strong Altered Expression [784]
PCYT1A DEQYXD4 Strong Biomarker [785]
PER1 DE9HF0I Strong Altered Expression [786]
PRODH DEVJIHS Strong Altered Expression [787]
PTGDS DER3H9C Strong Biomarker [788]
SULT1A1 DEYWLRK Strong Biomarker [294]
SULT2A1 DE0P6LK Strong Altered Expression [396]
UGT1A7 DEZO4N3 Strong Genetic Variation [789]
UGT2B17 DEAZDL8 Strong Biomarker [790]
NAT1 DE7OAB3 Definitive Biomarker [791]
------------------------------------------------------------------------------------
⏷ Show the Full List of 50 DME(s)
This Disease Is Related to 1204 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACAD8 OT3JI5GB Limited Biomarker [91]
ACTL6A OT0EC5BQ Limited Altered Expression [792]
ADGRL2 OTCXD2YR Limited Biomarker [793]
ANXA6 OT9KIQ0Y Limited Altered Expression [63]
ARHGEF2 OTBQTFRT Limited Altered Expression [794]
ARPC2 OTSOKOMY Limited Biomarker [795]
AXIN2 OTRMGQNU Limited Biomarker [796]
B3GALT5 OTWXPEMU Limited Posttranslational Modification [797]
B3GNT7 OT8UTTXF Limited Altered Expression [798]
BMPR1A OTQOA4ZH Limited Genetic Variation [799]
CA8 OT9Y8GA8 Limited Biomarker [800]
CACYBP OTJMZD2T Limited Biomarker [625]
CASP14 OTKY93H9 Limited Altered Expression [801]
CDX1 OTOHTMJE Limited Biomarker [802]
CEP55 OTGSG2PA Limited Genetic Variation [803]
CHFR OTRAD2TT Limited Posttranslational Modification [804]
CLEC4D OTT7X1UC Limited Genetic Variation [805]
CLPTM1L OTDJWQXI Limited Genetic Variation [806]
CNIH4 OT1TFJK0 Limited Biomarker [807]
CP OTM8JE4Y Limited Biomarker [808]
CTDSPL OTZJ0CZK Limited Biomarker [809]
CTTN OTJRG4ES Limited Altered Expression [810]
CUEDC2 OTWMOLAJ Limited Altered Expression [811]
CUL2 OTPF83PG Limited Genetic Variation [812]
CXCL17 OTRCEVIZ Limited Altered Expression [813]
CXCL3 OTSL94KH Limited Altered Expression [814]
DDB2 OTO8HVVB Limited Altered Expression [815]
DDIT3 OTI8YKKE Limited Biomarker [816]
DIAPH1 OTZBYPLH Limited Biomarker [817]
DLEC1 OTMKKBUW Limited Biomarker [818]
EIF3G OT5L1SRY Limited Biomarker [819]
FBLN1 OT5MHHOP Limited Genetic Variation [820]
FH OTEQWU6Q Limited Genetic Variation [805]
FUT1 OTODG57A Limited Genetic Variation [821]
GATAD2B OTJL128N Limited Altered Expression [63]
GORASP1 OTQS91S7 Limited Altered Expression [136]
GPRC5A OTPOCWR7 Limited Biomarker [822]
GPX2 OTXI2NTI Limited Altered Expression [823]
HNRNPF OTSMBXMF Limited Biomarker [824]
HOXB9 OTMVHQOU Limited Altered Expression [825]
IARS2 OTDX4SCA Limited Altered Expression [826]
IFNGR1 OTCTQBWW Limited Genetic Variation [92]
IL6ST OT1N9C70 Limited Biomarker [827]
INPP4B OTLROA7G Limited Biomarker [828]
IRF2 OTAZRUW3 Limited Genetic Variation [92]
ISYNA1 OT49ONSE Limited Altered Expression [110]
KLF14 OT8BXLBS Limited Altered Expression [829]
LEF1 OTWS5I5H Limited Biomarker [830]
LPIN1 OTQ75KF2 Limited Altered Expression [57]
LRG1 OTLD0KWA Limited Biomarker [226]
LRPPRC OTXSK5LP Limited Biomarker [827]
LRRC8A OT23OE7H Limited Biomarker [831]
LUM OTSRC874 Limited Altered Expression [832]
MACIR OTPSW8Y8 Limited Biomarker [81]
MBD2 OTUQPP0R Limited Biomarker [833]
MCM2 OTGGORIQ Limited Altered Expression [834]
MEST OT8Q4U8Y Limited Biomarker [835]
MFAP1 OTZN4FT3 Limited Biomarker [751]
MINDY4 OTBZ2SZB Limited Biomarker [836]
MOB1A OTSPBZ4Z Limited Altered Expression [837]
MSH3 OTD3YPVL Limited Altered Expression [838]
MYEOV OTDC7UHL Limited Biomarker [839]
NAA40 OTFLRVQO Limited Biomarker [840]
NAV2 OTGAOL01 Limited Altered Expression [841]
NFE2L3 OT1MGXT0 Limited Biomarker [842]
NKAP OT7K7I8Q Limited Biomarker [843]
NR2F6 OTNVO2B6 Limited Biomarker [844]
OXT OT48M72Z Limited Therapeutic [845]
PCBD1 OTDSRUD5 Limited Biomarker [846]
PDLIM4 OT23LZYY Limited Altered Expression [847]
PEAK1 OTVVM637 Limited Altered Expression [848]
PHF20 OTCBVH5P Limited Biomarker [849]
PLA2G10 OTRZ2L5A Limited Biomarker [153]
PLA2G2D OTU604XM Limited Biomarker [153]
PPM1H OTKSVU7S Limited Altered Expression [850]
PRDX2 OTLWCY9T Limited Biomarker [851]
PRKAG2 OTHTAM54 Limited Genetic Variation [852]
PRKN OTJBN41W Limited Genetic Variation [853]
PRRT2 OTCJUBDO Limited Altered Expression [854]
PTPA OTRGFOI7 Limited Biomarker [855]
PTPN3 OTSLZBVY Limited Genetic Variation [856]
PYROXD1 OTPGO23E Limited Biomarker [857]
RAB32 OTTR4H7S Limited Biomarker [858]
RAD21 OTQS84ZF Limited Genetic Variation [736]
RAD54B OTMWB2P2 Limited Biomarker [859]
RASSF1 OTEZIPB7 Limited Biomarker [178]
RBBP4 OTG3BT3M Limited Altered Expression [860]
RBM15B OTRJ9DT7 Limited Biomarker [276]
RBM3 OTAJ7R31 Limited Altered Expression [861]
RCOR1 OTREADPC Limited Biomarker [862]
RSPO2 OT3HHXU0 Limited Biomarker [863]
SASH1 OTQA8BD4 Limited Biomarker [864]
SCAF1 OT16TM3N Limited Altered Expression [865]
SCO2 OTJQQDRS Limited Biomarker [866]
SERTAD1 OTBHKZQP Limited Posttranslational Modification [867]
SMR3B OTL5HNM8 Limited Altered Expression [603]
SNAI2 OT7Y8EJ2 Limited Biomarker [868]
SPINK4 OTHTCW94 Limited Altered Expression [869]
SRF OTW18FQN Limited Altered Expression [870]
STRA6 OT2IDF27 Limited Biomarker [871]
SYNE1 OTSBSLUH Limited Biomarker [872]
SYT1 OTVTPOI6 Limited Altered Expression [136]
TENM4 OT91K3FC Limited Biomarker [144]
TET2 OTKKT03T Limited Biomarker [873]
TFG OT2KJENI Limited Genetic Variation [874]
TMED9 OTYGAQS0 Limited Biomarker [807]
TNS2 OTP72P0F Limited Altered Expression [875]
TPM3 OT5RU5G6 Limited Genetic Variation [876]
TRIM72 OTFAFXPC Limited Altered Expression [877]
TRMT11 OTRK0IOR Limited Biomarker [81]
CEMIP OTK80FYN Disputed Biomarker [878]
CEP85L OTSHJFOT Disputed Biomarker [879]
DBF4B OTARSHZM Disputed Altered Expression [880]
NR2C2 OTDZWVOJ Disputed Biomarker [731]
SFRP1 OT0U9G41 Disputed Posttranslational Modification [881]
TP73 OT0LUO47 Disputed Biomarker [882]
AADAC OT8VACT2 moderate Biomarker [883]
ACCS OTHIHI9D moderate Biomarker [755]
ALX4 OTNS9A29 moderate Posttranslational Modification [884]
ARHGEF1 OTXU4HBW moderate Biomarker [885]
BRINP1 OTEUVSCP moderate Biomarker [886]
BTF3 OT5ZZFJL moderate Biomarker [887]
CCAR2 OTLUDG5T moderate Biomarker [886]
CCL18 OT7JYSK9 moderate Altered Expression [888]
CFHR1 OT72R16T moderate Biomarker [889]
CIP2A OTVS2GXA moderate Altered Expression [890]
CMPK2 OTOG90R0 moderate Altered Expression [756]
DBN1 OTZVKG8A moderate Altered Expression [891]
DCDC2 OTSUFH1H moderate Biomarker [892]
DEDD OTIL349E moderate Biomarker [893]
DERL1 OTJUS74N moderate Altered Expression [894]
FBXW4 OTEGSZOX moderate Biomarker [883]
FOXO3 OTHXQG4P moderate Biomarker [895]
GRP OT8JDFNI moderate Biomarker [896]
H4C1 OTB71W46 moderate Biomarker [897]
HBP1 OTDPGGDV moderate Genetic Variation [898]
HCP5 OTV0YRI8 moderate Altered Expression [899]
HOXB3 OT9UC5PE moderate Biomarker [900]
HOXC13 OT52AVNA moderate Biomarker [901]
HSPB2 OTS01646 moderate Biomarker [189]
ISM1 OTZTK2TV moderate Altered Expression [902]
ITGB4 OT28UK84 moderate Altered Expression [903]
ITIH4 OT460OO1 moderate Biomarker [177]
JMJD6 OTILR7E4 moderate Biomarker [904]
JUND OTNKACJD moderate Biomarker [905]
KATNB1 OT7CLZKS moderate Biomarker [176]
KCTD12 OTPYKT4Z moderate Biomarker [166]
KDM2B OTDMCVW7 moderate Altered Expression [906]
LMTK2 OT93MVIC moderate Biomarker [907]
LYPD8 OT5B9NNM moderate Biomarker [908]
MAP2K6 OTK13JKC moderate Altered Expression [909]
MAP6 OTPUI00F moderate Genetic Variation [910]
MAPK6 OTDDNF3Q moderate Genetic Variation [197]
MED25 OTDBY87B moderate Biomarker [911]
MPZ OTAR2YXH moderate Biomarker [203]
MTMR3 OTBIT23O moderate Biomarker [201]
MUC3A OTI4XUDY moderate Altered Expression [912]
MYL9 OT6B22JB moderate Altered Expression [913]
MYOM2 OTD2UOXW moderate Genetic Variation [914]
NANOG OTUEY1FM moderate Biomarker [915]
NEU3 OTQ5PQOW moderate Altered Expression [916]
NLK OT2LETFS moderate Biomarker [917]
NWD1 OT4JMFPH moderate Genetic Variation [918]
OXA1L OTS0BFRD moderate Biomarker [919]
P2RX5 OTLBR20R moderate Biomarker [920]
P4HB OTTYNYPF moderate Biomarker [921]
PA2G4 OT7IG7HT moderate Biomarker [702]
PDCD4 OTZ6NXUX moderate Biomarker [922]
PHLDB2 OTDKMB2G moderate Biomarker [923]
PLA2G15 OT6VJTPA moderate Biomarker [755]
PLAAT4 OTI66SAJ moderate Biomarker [354]
PLEKHA8 OT03870U moderate Biomarker [924]
PMP22 OTXWYWCZ moderate Biomarker [203]
PRPF6 OT3U0ABN moderate Biomarker [925]
PSD OTUZIXUZ moderate Genetic Variation [914]
RCHY1 OTAE7504 moderate Biomarker [926]
RELA OTUJP9CN moderate Altered Expression [136]
RETREG1 OTYOSLZX moderate Posttranslational Modification [927]
RHOC OTOLE1FT moderate Biomarker [928]
RPL28 OTEVRCBO moderate Biomarker [929]
RTKN OTSS8XR6 moderate Biomarker [930]
SATB2 OT2W80XC moderate Biomarker [931]
SHMT2 OT5NCAZN moderate Biomarker [932]
SMAD2 OTC6VB4K moderate Biomarker [933]
SMURF1 OT5UIZR8 moderate Biomarker [934]
SMURF2 OT3TRVL7 moderate Biomarker [223]
SOX17 OT9H4WWE moderate Biomarker [935]
STAT5A OTBSJGN3 moderate Altered Expression [936]
STT3A OTDPS6AV moderate Altered Expression [314]
TM4SF5 OTPAV531 moderate Biomarker [937]
TMED3 OTNOPHHC moderate Biomarker [938]
TNFAIP8L1 OTVVKOTV moderate Biomarker [939]
TRAP1 OTNG0L8J moderate Altered Expression [940]
TRAPPC9 OTF0CVMC moderate Biomarker [941]
A2M OTFTX90K Strong Biomarker [454]
ABCE1 OTH19LOA Strong Biomarker [942]
ABHD5 OTY829Z3 Strong Biomarker [943]
ACAN OTUOCW8K Strong Altered Expression [628]
ACAP2 OTYNZPC4 Strong Altered Expression [683]
ACOXL OTW680HT Strong Genetic Variation [408]
ACRBP OT0MK3L1 Strong Altered Expression [944]
ACSL1 OTB06ESI Strong Genetic Variation [945]
ACSL4 OTI71MUJ Strong Biomarker [946]
ACTA2 OTEDLG8E Strong Biomarker [294]
ACTG2 OTRDWUO0 Strong Biomarker [294]
ACTR1B OTGBCKLO Strong Genetic Variation [55]
ACTRT3 OT2U08K8 Strong Genetic Variation [55]
ADA2 OTGCV24S Strong Biomarker [947]
ADAMTS12 OTG7HEA2 Strong Altered Expression [948]
ADAMTS15 OTYB6JS3 Strong Biomarker [949]
ADAMTS18 OTRMFI04 Strong Biomarker [950]
ADAMTSL3 OTMC2WFG Strong Biomarker [951]
ADCY9 OT1IZT5K Strong Altered Expression [952]
ADIPOR1 OT65ZFZN Strong Genetic Variation [953]
ADIPOR2 OT2HDTL8 Strong Biomarker [954]
ADNP OTEGICWR Strong Altered Expression [955]
AFDN OTTRU341 Strong Biomarker [956]
AFMID OTFSM0TL Strong Altered Expression [957]
AGL OTWBM7WY Strong Biomarker [958]
AGO1 OTD3R434 Strong Biomarker [959]
AGO2 OT4JY32Q Strong Biomarker [960]
AHRR OTSJ12W6 Strong Altered Expression [961]
AHSA1 OTC7AFHT Strong Biomarker [251]
AIM2 OT86QUI8 Strong Biomarker [962]
AIMP1 OTTA5C3U Strong Altered Expression [482]
AKAP10 OTPNFTOU Strong Altered Expression [963]
AKAP12 OTCVRDDX Strong Altered Expression [964]
AKAP3 OT42QOFG Strong Altered Expression [965]
AKAP4 OTL4Z99V Strong Altered Expression [966]
ALDH1A3 OT1C9NKQ Strong Biomarker [967]
ALDH3A1 OTAYZZE6 Strong Altered Expression [341]
ALDH7A1 OTV57BZD Strong Biomarker [968]
ALPG OTCIM29R Strong Genetic Variation [969]
ALPP OTZU4G9W Strong Altered Expression [265]
ALX3 OTXZ25PZ Strong Biomarker [970]
AMOTL2 OTRCTKV9 Strong Altered Expression [971]
AMPD3 OT5SP1KJ Strong Biomarker [972]
ANGPTL2 OTB6JG41 Strong Altered Expression [255]
ANKRD36B OT3MW415 Strong Altered Expression [973]
ANOS1 OTZJT4KN Strong Altered Expression [974]
ANTXR1 OT5W1GPC Strong Biomarker [975]
APAF1 OTJWIVY0 Strong Therapeutic [976]
APCDD1 OTV9AD0L Strong Biomarker [977]
APIP OT8ZABOU Strong Biomarker [646]
APOBEC1 OTY8QX2R Strong Biomarker [978]
AQP5 OT77GBY8 Strong Biomarker [187]
ARC OTN2QQPG Strong Biomarker [979]
ARHGAP11A OTVQCFVP Strong Altered Expression [980]
ARHGAP17 OTEABPLV Strong Biomarker [981]
ARHGAP24 OTCQCEZS Strong Biomarker [882]
ARHGEF17 OTUGS4FL Strong Biomarker [982]
ARHGEF5 OTUVGFT9 Strong Biomarker [983]
ARHGEF7 OT9BPJCL Strong Biomarker [984]
ARID3A OTZZ4SFP Strong Biomarker [985]
ARNT OTMSIEZY Strong Altered Expression [986]
ASAH1 OT1DNGXL Strong Biomarker [987]
ASCC1 OTH4VAP9 Strong Altered Expression [988]
ASCC2 OT3B204T Strong Altered Expression [535]
ASF1A OT4S44GP Strong Biomarker [989]
ASL OTI2NGQR Strong Altered Expression [990]
ASPRV1 OT8WVIBW Strong Altered Expression [209]
ATF1 OT251CI0 Strong Genetic Variation [224]
ATF6 OTAFHAVI Strong Altered Expression [890]
ATG3 OT28VBVK Strong Altered Expression [991]
ATG4B OTQ4RNRM Strong Biomarker [992]
ATN1 OTNZFLKY Strong Biomarker [993]
ATOH1 OTBZYG2R Strong Biomarker [994]
ATP2A3 OTFYDEES Strong Altered Expression [995]
ATP2B4 OTMWFDAC Strong Altered Expression [996]
ATP5F1E OTMPLAIS Strong Altered Expression [997]
ATRNL1 OTY5JUX2 Strong Altered Expression [265]
AXIN1 OTRGZGZ5 Strong Biomarker [998]
B3GNT8 OTDK2PQD Strong Biomarker [999]
B3GNTL1 OTYWGHF1 Strong Biomarker [999]
B4GALNT3 OT6BFB22 Strong Biomarker [1000]
BAALC OTUZSRVF Strong Genetic Variation [1001]
BABAM1 OTCFPER6 Strong Genetic Variation [476]
BAD OT63ERYM Strong Genetic Variation [1002]
BAG1 OTRQNIA4 Strong Biomarker [1003]
BAMBI OTCEJ8W5 Strong Altered Expression [1004]
BARD1 OTTC0Z9Y Strong Biomarker [1005]
BATF3 OTI61WXQ Strong Biomarker [1006]
BCAM OTHZOPSD Strong Biomarker [1007]
BCL10 OT47MCLI Strong Altered Expression [1008]
BCL11B OT8KKCVJ Strong Genetic Variation [1009]
BCL2L11 OTNQQWFJ Strong Biomarker [1010]
BCL2L12 OTS6IFZY Strong Posttranslational Modification [1011]
BCL9 OTRBIPR4 Strong Biomarker [1012]
BHLHE22 OTZUQY5L Strong Biomarker [1013]
BICC1 OTYRKIJ1 Strong Genetic Variation [348]
BIN1 OTK8O0X8 Strong Altered Expression [1014]
BIRC6 OTCQJAB0 Strong Biomarker [1015]
BLM OTEJOAJX Strong Biomarker [1016]
BLNK OTSSPF6F Strong Biomarker [1017]
BMP3 OTCTI0UW Strong Biomarker [1018]
BMP5 OTC0Y6E0 Strong Genetic Variation [224]
BNIP3 OT4SO7J4 Strong Altered Expression [1019]
BOC OTXBCY9W Strong Genetic Variation [224]
BRAP OTB7BAFQ Strong Biomarker [1020]
BRCA1 OT5BN6VH Strong Biomarker [993]
BRI3 OT1RWIH7 Strong Biomarker [1021]
BTBD9 OTWQ6GA3 Strong Genetic Variation [1022]
BVES OT4GT1WC Strong Biomarker [1023]
C1GALT1 OT2ZSZ6P Strong Altered Expression [1024]
C1QL3 OT4TZH3J Strong Biomarker [1025]
CABLES1 OTMN4XSX Strong Biomarker [1026]
CABLES2 OTGD9A2A Strong Genetic Variation [225]
CACNB1 OTV42SIT Strong Altered Expression [336]
CADM1 OTRWG9QS Strong Altered Expression [1027]
CALB2 OTSNMCG9 Strong Altered Expression [1028]
CALM2 OTNYA92F Strong Biomarker [1029]
CALML3 OTM8DNQU Strong Biomarker [1030]
CALU OTSYQN71 Strong Biomarker [320]
CAMKMT OTLJBRUW Strong Biomarker [1029]
CAMTA2 OT6PIWF4 Strong Biomarker [1031]
CARD10 OT2RPM4I Strong Altered Expression [1032]
CARD8 OTXXZYWU Strong Altered Expression [1033]
CARD9 OTJ81AWD Strong Biomarker [1034]
CASK OT8EF7ZF Strong Biomarker [1035]
CASP8AP2 OTTWT68S Strong Biomarker [1036]
CASZ1 OTWJ2OR8 Strong Biomarker [1037]
CBFA2T2 OTNOIB23 Strong Biomarker [984]
CBLL1 OTZUQBYX Strong Altered Expression [1038]
CBLN2 OT29SSBE Strong Genetic Variation [1022]
CBX1 OT2L4XZX Strong Altered Expression [1039]
CBX3 OTOP9RLD Strong Biomarker [1040]
CBX5 OT8VYY84 Strong Biomarker [1041]
CBX8 OT4U5V1T Strong Altered Expression [1042]
CCAR1 OTUXLQZZ Strong Altered Expression [1043]
CCDC66 OTE8VSSO Strong Biomarker [1044]
CCDC80 OTOZSYEM Strong Biomarker [1045]
CCDC83 OTF1ETS6 Strong Altered Expression [1046]
CCDC88A OT3SSYYC Strong Altered Expression [1047]
CCL27 OTUZYC61 Strong Altered Expression [265]
CCL4L2 OTDBSXOU Strong Biomarker [1048]
CCN4 OT69BER9 Strong Biomarker [1049]
CCNC OTMVK4K4 Strong Genetic Variation [1050]
CCND2 OTDULQF9 Strong Genetic Variation [225]
CCNDBP1 OTBWG1M0 Strong Altered Expression [1051]
CCNH OTKDU3SR Strong Biomarker [81]
CCNL2 OT0NIKYM Strong Biomarker [1052]
CCT4 OT5D452X Strong Biomarker [1053]
CD151 OTF3UZS7 Strong Altered Expression [1054]
CD63 OT2UGZA9 Strong Altered Expression [885]
CD81 OTQFXNAZ Strong Altered Expression [1055]
CDC42 OT5QBC5M Strong Biomarker [319]
CDCP1 OTD7RRWK Strong Altered Expression [316]
CDH13 OTD2CYM5 Strong Posttranslational Modification [1056]
CDH17 OT9EV2XK Strong Altered Expression [1057]
CDHR2 OTTHEUPO Strong Altered Expression [1058]
CDHR5 OTTBWQMN Strong Altered Expression [1059]
CDK14 OT385ZH1 Strong Biomarker [1060]
CDKN3 OTBE3H07 Strong Biomarker [1061]
CDO1 OTLG1P77 Strong Biomarker [1062]
CEACAM4 OT0C7YUD Strong Altered Expression [1063]
CEACAM8 OTLL9WWO Strong Biomarker [1064]
CEP131 OT6PF80T Strong Altered Expression [579]
CERS4 OTV5ENAX Strong Biomarker [1065]
CERS5 OT5A2DNI Strong Biomarker [1065]
CETN1 OTGQ8JOZ Strong Biomarker [1066]
CFAP44 OT1273MD Strong Genetic Variation [1022]
CFL1 OTT6D5MH Strong Biomarker [1067]
CHAF1A OTXSSY4H Strong Altered Expression [1068]
CHCHD5 OTVESFOA Strong Biomarker [1069]
CHD1 OT9R9G0H Strong Genetic Variation [224]
CHI3L1 OT2Z7VJH Strong Altered Expression [1070]
CHMP5 OTQWZL6R Strong Biomarker [1071]
CHPT1 OT4FJ0K3 Strong Biomarker [1072]
CHRDL2 OTJU2I5H Strong Genetic Variation [224]
CHST4 OTESMIW5 Strong Biomarker [1073]
CHTF18 OTQK3FI4 Strong Biomarker [1074]
CILK1 OTWOYEYP Strong Biomarker [503]
CIRBP OTXWTPBL Strong Biomarker [612]
CITED2 OT812TV7 Strong Biomarker [1075]
CIZ1 OT3UKHPI Strong Biomarker [1076]
CKAP4 OTDUC9ME Strong Biomarker [882]
CKB OTUCKOTT Strong Altered Expression [1077]
CKM OTME0KO7 Strong Biomarker [294]
CKS1B OTNUPLUJ Strong Altered Expression [556]
CLCA2 OTF191LZ Strong Biomarker [331]
CLCN4 OT4A2UWF Strong Biomarker [1078]
CLDN1 OT27KV99 Strong Biomarker [1079]
CLDN2 OTRF3D6Y Strong Altered Expression [1080]
CLDN3 OT71MN9S Strong Biomarker [1081]
CLDN7 OTNE0XHQ Strong Biomarker [1079]
CLEC3A OTTOAEGT Strong Genetic Variation [675]
CLEC3B OTFD29NF Strong Altered Expression [1082]
CLEC4M OT2WUIIP Strong Biomarker [1083]
CLUAP1 OTESP4WL Strong Altered Expression [1084]
CNBP OTTGM9NK Strong Altered Expression [1085]
CNDP2 OTJR9436 Strong Biomarker [1086]
CNN3 OTJTAXAP Strong Altered Expression [1087]
COL12A1 OTHLTV53 Strong Biomarker [781]
COL4A2 OTJK1LKN Strong Genetic Variation [224]
COL4A6 OTUREU5Z Strong Biomarker [1088]
COLCA1 OT8BP6UD Strong Genetic Variation [225]
COMP OTS2FPMI Strong Biomarker [1089]
COPS6 OTG9AAG0 Strong Biomarker [1090]
CORO1A OTVAZOHC Strong Altered Expression [1091]
COTL1 OT6YCNLF Strong Biomarker [1030]
COX1 OTG3O9BN Strong Biomarker [221]
COX3 OTNNGBYJ Strong Biomarker [1092]
COX5A OTP0961M Strong Biomarker [1093]
COX8A OTU0NR39 Strong Biomarker [1093]
CPOX OTIAY121 Strong Biomarker [1093]
CPQ OTTNZNLD Strong Biomarker [1094]
CPSF4 OT53UK5L Strong Biomarker [1095]
CRABP1 OTISDG5X Strong Genetic Variation [658]
CRB3 OTQKPTMU Strong Biomarker [1096]
CREM OTJIJ5AL Strong Biomarker [1097]
CRISP2 OT8HLTV5 Strong Biomarker [1098]
CRISPLD2 OTVSFHTL Strong Biomarker [1099]
CRKL OTOYSD1R Strong Biomarker [1100]
CRTC3 OTVIGVUW Strong Genetic Variation [55]
CRYGC OTYSTQWI Strong Biomarker [1101]
CSGALNACT1 OTBML9D9 Strong Altered Expression [1102]
CSN2 OT22C0PD Strong Altered Expression [1103]
CSRNP1 OTDK1FPH Strong Altered Expression [1104]
CSRP1 OTUS7RM2 Strong Genetic Variation [1105]
CSRP3 OTECBJMV Strong Biomarker [1030]
CST1 OTE4I83Q Strong Altered Expression [1106]
CST5 OTHJXNJG Strong Biomarker [1107]
CSTB OT3U0JF8 Strong Altered Expression [1108]
CTBS OT135K92 Strong Biomarker [562]
CTHRC1 OTV88X2G Strong Altered Expression [1109]
CTNNA1 OTFC725Z Strong Genetic Variation [1110]
CTNND1 OTUMPSHR Strong Biomarker [1111]
CUL1 OTXPE1UZ Strong Biomarker [532]
CUL4A OTTBV70J Strong Altered Expression [1112]
CUL4B OT2QX4DO Strong Biomarker [1113]
CXCL14 OTM189TA Strong Altered Expression [1114]
CXCL16 OTD49T9R Strong Altered Expression [1114]
CXCL6 OTFTCQ4O Strong Biomarker [1115]
CYB5D2 OTX10KKR Strong Genetic Variation [1116]
CYB5R1 OTMDHMLA Strong Altered Expression [1117]
CYFIP2 OTCAY35T Strong Biomarker [1118]
CYP2W1 OTXSB1AE Strong Biomarker [1119]
D2HGDH OTLHXW69 Strong Biomarker [1120]
DACT1 OT19Z704 Strong Biomarker [1121]
DACT2 OTNLCC0K Strong Altered Expression [1122]
DAPK2 OTWODUQG Strong Altered Expression [706]
DCAF1 OT3ZDVOE Strong Genetic Variation [1123]
DCBLD1 OTA702JK Strong Genetic Variation [1124]
DCTN6 OTI8PIN9 Strong Biomarker [1125]
DDA1 OTAZIAIH Strong Biomarker [1103]
DDB1 OTTR2L3Z Strong Altered Expression [1126]
DDHD1 OTWTHOWK Strong Biomarker [1127]
DDX17 OTXRMMBP Strong Biomarker [1128]
DDX3X OTDO4TRX Strong Biomarker [1129]
DDX53 OTHK3EGZ Strong Biomarker [88]
DEFA5 OT95CBQ9 Strong Biomarker [1130]
DEFB1 OT5SV0E4 Strong Altered Expression [1131]
DEFB103B OT8RWY64 Strong Altered Expression [355]
DEFB104A OTLQZR6K Strong Altered Expression [355]
DENND5B OTNDJJUR Strong Genetic Variation [135]
DENR OTXP9HOY Strong Altered Expression [706]
DGKB OTTT9SZJ Strong Biomarker [1132]
DGKE OTWS86AS Strong Biomarker [1132]
DGUOK OT78HUZB Strong Biomarker [1132]
DHDDS OTVLYBUS Strong Biomarker [1072]
DHX36 OT8IGL9Y Strong Biomarker [1133]
DIP2B OTP6KH82 Strong Genetic Variation [343]
DIXDC1 OT87DXEG Strong Altered Expression [1134]
DKK4 OTWCCVF6 Strong Biomarker [1135]
DLC1 OTP8LMCR Strong Biomarker [818]
DLX4 OTLWVCN4 Strong Altered Expression [1136]
DMBT1 OTVNU9D9 Strong Biomarker [294]
DNAJA3 OT61924T Strong Altered Expression [1137]
DNLZ OT48CG1W Strong Biomarker [1138]
DNM1L OTXK1Q1G Strong Posttranslational Modification [706]
DNM3 OTDMUGCR Strong Altered Expression [851]
DOCK3 OTF3YS2W Strong Genetic Variation [1022]
DOK1 OTGVRLW6 Strong Biomarker [1139]
DPPA4 OTAEOACS Strong Altered Expression [1140]
DPYS OTLTUIVL Strong Biomarker [1141]
DRG1 OTIFYMI3 Strong Genetic Variation [1022]
DSC3 OTYG47F8 Strong Biomarker [1142]
DSCC1 OTPUVLZT Strong Altered Expression [1074]
DSG2 OTJPB2TO Strong Altered Expression [1143]
DST OTHZBM4X Strong Biomarker [203]
DSTN OTMXO4YB Strong Altered Expression [492]
DUOX2 OTU14HCN Strong Biomarker [1144]
DUSP2 OTH54FMR Strong Altered Expression [1145]
DVL2 OTMNYNCM Strong Altered Expression [1146]
DYNLL1 OTR69LHT Strong Biomarker [818]
E2F4 OTB3JFH4 Strong Biomarker [1147]
ECM1 OT1K65VW Strong Altered Expression [1148]
ECT2L OTOSDMGV Strong Genetic Variation [675]
EDIL3 OTDVVNS0 Strong Biomarker [1149]
EDN3 OTN7Q9BE Strong Posttranslational Modification [369]
EEF1A1 OT00THXS Strong Altered Expression [1150]
EFCAB2 OTXEFI4O Strong Genetic Variation [135]
EFNB2 OT0DCUOM Strong Altered Expression [1151]
EIF3B OTF67VPH Strong Biomarker [1152]
EIF3C OTR8RF9X Strong Biomarker [1153]
EIF3D OTDOMP80 Strong Biomarker [1154]
EIF3E OTI0WG98 Strong Altered Expression [1155]
EIF3I OTE07WND Strong Biomarker [1156]
EIF3M OTVWEV60 Strong Biomarker [1157]
EIF4B OTE8TXA8 Strong Altered Expression [67]
EIF4ENIF1 OTZWDB2X Strong Genetic Variation [1022]
ELK1 OTH9MXD6 Strong Biomarker [1158]
ELOVL5 OT375W1Z Strong Genetic Variation [1159]
EME1 OTD9RKD9 Strong Biomarker [1160]
EMILIN1 OT94R6M1 Strong Altered Expression [1161]
ENPP7 OTWOBMQ9 Strong Biomarker [1162]
ENTPD5 OTFH05B9 Strong Biomarker [781]
ENTR1 OT5F18V3 Strong Altered Expression [1163]
EOMES OTB9VQFA Strong Altered Expression [1164]
ERCC1 OTNPYQHI Strong Biomarker [1165]
ERCC6 OT2QZKSF Strong Altered Expression [1166]
ETV4 OT8C98UZ Strong Biomarker [1167]
ETV6 OTCZMG61 Strong Genetic Variation [1168]
EVL OTZ8ZDNY Strong Biomarker [1169]
EXOC7 OT4YA137 Strong Biomarker [1170]
EYA4 OTINGR3Z Strong Biomarker [1013]
FABP7 OTRE2H4G Strong Biomarker [1171]
FADD OTV7GFHH Strong Genetic Variation [1172]
FAM193A OTT0W53G Strong Genetic Variation [1022]
FAM3B OTC2S91N Strong Biomarker [1173]
FANCB OTMZTXB5 Strong Altered Expression [341]
FANCC OTTIDM3P Strong Genetic Variation [1016]
FANCM OTNJG99Z Strong Altered Expression [341]
FBP1 OTQBANEP Strong Biomarker [1174]
FBXL5 OT93D50X Strong Biomarker [1175]
FBXO39 OTPRR6SK Strong Biomarker [1176]
FCMR OTI7I47T Strong Biomarker [1177]
FEM1B OTFE2ELA Strong Altered Expression [1178]
FEN1 OT6QGG7O Strong Genetic Variation [55]
FERMT1 OT626PBA Strong Altered Expression [1179]
FGF20 OTJIQ8YZ Strong Altered Expression [1180]
FGF9 OT2SKDGM Strong Altered Expression [1181]
FHL2 OT0OAYWT Strong Altered Expression [1182]
FLOT1 OT0JPPJZ Strong Altered Expression [1183]
FLT3LG OTU0YGC4 Strong Biomarker [1184]
FMN1 OT9CID5R Strong Genetic Variation [224]
FOSB OTW6C05J Strong Altered Expression [1185]
FOXA2 OTJOCVOY Strong Altered Expression [1186]
FOXJ1 OT7LLBZ7 Strong Altered Expression [1187]
FOXK1 OTLZGS7J Strong Biomarker [1188]
FOXN3 OTOJYJZP Strong Biomarker [1189]
FRY OT74IAG2 Strong Genetic Variation [476]
FSTL1 OT6KEZUD Strong Biomarker [1190]
FUT6 OTBZUQ7F Strong Altered Expression [1191]
FUT7 OTJF6BSN Strong Altered Expression [1191]
FZD1 OTZATHVS Strong Biomarker [1192]
FZD2 OT952ML1 Strong Biomarker [1193]
FZD5 OTXFFY56 Strong Biomarker [1192]
FZR1 OT0WGWZS Strong Altered Expression [1194]
GABPA OT9YB2SA Strong Altered Expression [1195]
GADD45A OTDRV63V Strong Genetic Variation [1196]
GALNT12 OTVIBUST Strong Genetic Variation [1197]
GALNT4 OT6WKC13 Strong Biomarker [1198]
GALNT6 OTOQQVH1 Strong Biomarker [1199]
GATA6 OTO2BC0F Strong Altered Expression [1200]
GC OTWS63BY Strong Biomarker [1201]
GCNT2 OTRUIMC4 Strong Biomarker [1202]
GCNT3 OTQ9ALTR Strong Biomarker [1203]
GEMIN2 OT4L6TLL Strong Biomarker [1204]
GFER OTVK43OK Strong Altered Expression [1205]
GINS3 OT8NVXTD Strong Biomarker [1206]
GIT1 OTHO92S5 Strong Biomarker [335]
GLRX3 OTUPAU1N Strong Altered Expression [538]
GLS2 OT08MSHL Strong Altered Expression [1207]
GNAI2 OTTLGRGH Strong Genetic Variation [1208]
GNAS OTMH8BKJ Strong Genetic Variation [135]
GNB5 OT3ZSAXH Strong Biomarker [982]
GNG12 OTOGF42G Strong Genetic Variation [1022]
GOLPH3 OTDLGYM3 Strong Biomarker [1209]
GOT2 OT6XBWN0 Strong Altered Expression [1210]
GPATCH1 OTQRDBY6 Strong Genetic Variation [1211]
GPC1 OTQKRSSV Strong Biomarker [1212]
GPLD1 OTUUQOVY Strong Altered Expression [1213]
GPR143 OTWUA2AV Strong Genetic Variation [1214]
GPR42 OTEB0ROY Strong Biomarker [241]
GPX3 OT6PK94R Strong Biomarker [823]
GRAP2 OTS5NIZ3 Strong Biomarker [251]
GRHL1 OTZ4MNEW Strong Biomarker [1215]
GSDME OT1ZWY32 Strong Altered Expression [1216]
GSTK1 OTDNGWAF Strong Biomarker [750]
GSTM5 OTMMBFY8 Strong Biomarker [294]
GSTT2 OTANW3TJ Strong Altered Expression [1217]
GUCA2A OTUSF75G Strong Biomarker [1218]
GUCA2B OTZERX04 Strong Genetic Variation [1105]
GUCY1A1 OTPTCBUN Strong Biomarker [294]
H2AX OT18UX57 Strong Genetic Variation [904]
HAND1 OTN4IPVV Strong Posttranslational Modification [1219]
HAND2 OTCXYW4Y Strong Biomarker [416]
HAPLN1 OTXWR9TJ Strong Biomarker [972]
HAS3 OTPM8IL8 Strong Altered Expression [1220]
HAVCR2 OTOL603T Strong Biomarker [1221]
HBD OTRQG4WA Strong Altered Expression [355]
HCFC1 OT0UCK62 Strong Biomarker [1222]
HERC2 OTNQYKOB Strong Genetic Variation [1022]
HES1 OT8P19W2 Strong Biomarker [1223]
HEY1 OTJQL0I3 Strong Altered Expression [1224]
HEY2 OTU4J3ZI Strong Genetic Variation [1225]
HHIP OT77RQYS Strong Genetic Variation [224]
HIC1 OTI9TWY4 Strong Genetic Variation [1226]
HIP1 OT7AKCFQ Strong Biomarker [1227]
HLA-E OTX1CTFB Strong Altered Expression [1228]
HLA-F OT76CM19 Strong Genetic Variation [1022]
HLTF OTRX2OSF Strong Posttranslational Modification [1229]
HM13 OTGEO1LP Strong Biomarker [1118]
HMMR OT4M0JTZ Strong Altered Expression [1230]
HNF1B OTSYIC3T Strong Genetic Variation [476]
HNRNPC OT47AK4C Strong Biomarker [1231]
HNRNPDL OTB3BFCV Strong Altered Expression [1232]
HNRNPL OT0DJX74 Strong Altered Expression [1233]
HNRNPLL OTA6Q5E0 Strong Altered Expression [1234]
HNRNPM OTFU3OEZ Strong Biomarker [1235]
HOOK2 OTPO4NQV Strong Biomarker [474]
HOXA3 OTIX5XFB Strong Altered Expression [1236]
HOXA4 OTNVTQDT Strong Altered Expression [1237]
HOXA6 OTHJP8M2 Strong Genetic Variation [443]
HOXD10 OT0NOWU2 Strong Posttranslational Modification [928]
HPS5 OTLO2374 Strong Biomarker [892]
HSFY2 OTG2O6S4 Strong Biomarker [1238]
HSPA12A OTFOCDD6 Strong Genetic Variation [1239]
HSPA2 OTSDET7B Strong Biomarker [294]
HSPH1 OTVRR73T Strong Altered Expression [1240]
HTN3 OTEUXA81 Strong Altered Expression [396]
HYAL2 OTTVINXW Strong Genetic Variation [1241]
ID3 OTUULW5Z Strong Biomarker [294]
IFI27 OTI2XGIT Strong Biomarker [1125]
IFITM3 OT2QP8D3 Strong Altered Expression [1242]
IFRD1 OT4SQMLQ Strong Altered Expression [1243]
IGF2BP1 OT9G360P Strong Biomarker [1118]
IGF2BP2 OT4ZSEEE Strong Biomarker [1244]
IGFBP4 OT2HZRBD Strong Biomarker [1245]
IHH OT1DWGXC Strong Altered Expression [1246]
IL22RA1 OTGVKLBR Strong Altered Expression [1247]
IL22RA2 OTGOFDCY Strong Biomarker [1248]
IL2RG OTRZ3OMY Strong Biomarker [1249]
IL34 OTZ15VVK Strong Biomarker [1250]
IL4I1 OTK54C63 Strong Altered Expression [1251]
IMMP1L OTA6LOLR Strong Biomarker [1118]
IMMP2L OT9WGAFD Strong Biomarker [1252]
IMPA1 OTBUVW1Z Strong Biomarker [1020]
ING1 OTEZBRKW Strong Biomarker [1253]
ING2 OT6H0EWF Strong Altered Expression [1254]
ING4 OT0VVG4V Strong Biomarker [1255]
INHA OT7HWCO3 Strong Altered Expression [1256]
INO80 OTJBMS8T Strong Biomarker [1257]
INPPL1 OTCDAVBQ Strong Biomarker [1258]
INSIG2 OTX4VY51 Strong Biomarker [1259]
IPP OTCGBS3H Strong Biomarker [1260]
IQGAP1 OTZRWTGA Strong Biomarker [1261]
IRAK2 OT6Y1QZN Strong Biomarker [1262]
IRF9 OTK4MYQJ Strong Altered Expression [1263]
IRS4 OTTOL40K Strong Biomarker [1264]
IRX5 OT05J514 Strong Biomarker [1265]
ITGA2B OT4Y17PY Strong Altered Expression [1266]
ITGA3 OTBCH21D Strong Biomarker [540]
ITGA7 OTTBTAYW Strong Biomarker [294]
ITGAX OTOGIMHE Strong Biomarker [1267]
ITIH5 OTP46PZM Strong Altered Expression [1268]
ITPRID2 OTO3JDX5 Strong Biomarker [1269]
JADE3 OTEQR3MN Strong Biomarker [1270]
JAG1 OT3LGT6K Strong Altered Expression [1271]
JAM2 OTHVJJRJ Strong Biomarker [958]
JARID2 OT14UM8H Strong Biomarker [1272]
JAZF1 OTXTYSYD Strong Genetic Variation [982]
JUNB OTG2JXV5 Strong Altered Expression [1185]
KANK2 OT3SZIWM Strong Genetic Variation [625]
KARS1 OT0EU4SV Strong Biomarker [1273]
KAT5 OTL7257A Strong Altered Expression [1274]
KCMF1 OTVTKFAU Strong Biomarker [1275]
KCNIP4 OTB1BS0X Strong Genetic Variation [1022]
KDM4B OT5P1UPY Strong Biomarker [1276]
KDM8 OTCN5ST8 Strong Biomarker [1277]
KIF2A OT2WQ6QD Strong Biomarker [474]
KIF2C OTJ8G3NP Strong Altered Expression [1278]
KLF13 OTMIKHZ4 Strong Biomarker [336]
KLF2 OTIP1UFX Strong Biomarker [1279]
KLF5 OT1ABI9N Strong Genetic Variation [224]
KLF6 OTQY9S7F Strong Biomarker [245]
KLHL1 OTAX6SAD Strong Altered Expression [1280]
KLK13 OT8LOD2U Strong Biomarker [1281]
KMT2B OTMMAZQX Strong Altered Expression [1042]
KPNA2 OTU7FOE6 Strong Biomarker [1282]
KRIT1 OT58AP1I Strong Biomarker [1029]
KRT1 OTIOJWA4 Strong Biomarker [1283]
KRT8 OTTM4X11 Strong Genetic Variation [476]
L1TD1 OTB2W20Y Strong Genetic Variation [135]
LAMA5 OTIIXE4M Strong Genetic Variation [224]
LAMC1 OTIG527N Strong Genetic Variation [225]
LAT2 OTWJDKIH Strong Biomarker [1284]
LATS1 OTOOCG4R Strong Biomarker [1285]
LAYN OT9A9Q1X Strong Biomarker [1286]
LBR OT1HG3HG Strong Biomarker [1287]
LDHB OT9B1CT3 Strong Altered Expression [431]
LGALS3BP OT9AGQKH Strong Biomarker [1288]
LGALS8 OT71LJ8T Strong Altered Expression [1289]
LGALS9 OT7MF91K Strong Altered Expression [1290]
LIG4 OT40DNXU Strong Altered Expression [238]
LIMA1 OTONPC9R Strong Genetic Variation [1291]
LIMD2 OTSIFTD8 Strong Biomarker [1292]
LIMS1 OT729S0T Strong Biomarker [1260]
LIMS2 OTZ7IIPM Strong Altered Expression [1260]
LIMS3 OTTMS7V8 Strong Altered Expression [1260]
LIN28B OTVWP0FN Strong Altered Expression [1293]
LIPC OTZY5SC9 Strong Altered Expression [1294]
LLGL1 OTAIQSXZ Strong Biomarker [1295]
LMNB1 OT100T3P Strong Altered Expression [1296]
LNPK OTOBNX6G Strong Biomarker [1297]
LRATD1 OT65IL83 Strong Altered Expression [1298]
LRIG1 OTY5HZN5 Strong Biomarker [1299]
LRIT1 OTNEQPMZ Strong Biomarker [558]
LRP1B OT4YZG2N Strong Biomarker [1300]
LSAMP OTYXVQX2 Strong Genetic Variation [675]
LSR OTR8Y32X Strong Altered Expression [1301]
LTBP3 OTME98V7 Strong Biomarker [1302]
LUC7L3 OTKDED8A Strong Altered Expression [162]
LYPD5 OTGP7UKA Strong Altered Expression [1303]
MACC1 OTV3DLX0 Strong Altered Expression [886]
MACF1 OTVIHD77 Strong Genetic Variation [1304]
MACROD2 OTNQCHC6 Strong Altered Expression [1305]
MACROH2A1 OTV2DQDD Strong Biomarker [1306]
MAD2L2 OT24ZO59 Strong Biomarker [1307]
MAEL OTZ2VU30 Strong Biomarker [1308]
MAK16 OTD546E5 Strong Biomarker [1309]
MALL OTKGZ89D Strong Altered Expression [249]
MAMSTR OT4J6Z7G Strong Genetic Variation [55]
MAP1LC3B OTUYHB84 Strong Biomarker [1310]
MARCHF2 OTADQ0OA Strong Biomarker [1311]
MARCKSL1 OT13J2FM Strong Altered Expression [1312]
MASTL OTQ7YKK5 Strong Altered Expression [1313]
MAX OTKZ0YKM Strong Genetic Variation [1314]
MBD4 OTWR9YXE Strong Biomarker [1315]
MCC OTQVI1EM Strong Altered Expression [341]
MECOM OTP983W8 Strong Altered Expression [312]
MED1 OTOO24C4 Strong Genetic Variation [1316]
MED12 OTQZ4D2X Strong Biomarker [1317]
MED13L OTSP1W0F Strong Altered Expression [1317]
MED15 OT0D0JVD Strong Biomarker [1318]
MEP1A OTY2Z48T Strong Biomarker [294]
METAP1D OT144G80 Strong Altered Expression [1319]
METTL16 OT99VP8Y Strong Biomarker [1320]
MFAP5 OT46VXSG Strong Altered Expression [1321]
MIEN1 OTCQ8DAD Strong Altered Expression [1322]
MIP OTEBLU3E Strong Biomarker [1323]
MIXL1 OT584VOQ Strong Altered Expression [1324]
MLKL OTDSLC81 Strong Altered Expression [1325]
MMP25 OT3BG37V Strong Altered Expression [1326]
MON1B OTJGDN94 Strong Altered Expression [1327]
MORC2 OT52A8BJ Strong Altered Expression [1328]
MPEG1 OT7DAO0F Strong Biomarker [453]
MPST OTCDPH5D Strong Biomarker [1329]
MRE11 OTGU8TZM Strong Genetic Variation [1330]
MRPL36 OTZ9QV3U Strong Genetic Variation [52]
MRPL41 OTG5URO4 Strong Biomarker [1331]
MRTFA OTCVXASM Strong Altered Expression [1332]
MS4A12 OTUCF3GW Strong Biomarker [1333]
MSC OTBRPZL5 Strong Biomarker [1334]
MSN OTZJ4J6G Strong Biomarker [1335]
MST1 OTOC4UNG Strong Altered Expression [1336]
MSTO1 OT37XCNP Strong Biomarker [301]
MSX2 OT1WDKE1 Strong Biomarker [1337]
MT1F OTZVUYG1 Strong Posttranslational Modification [780]
MTHFD1 OTMKHVWC Strong Genetic Variation [1338]
MTX1 OTLSDNZO Strong Genetic Variation [476]
MUC13 OTWKS9MF Strong Altered Expression [1339]
MUC4 OTLT11V1 Strong Altered Expression [1340]
MUS81 OTVZ4E60 Strong Biomarker [1341]
MVP OTJGHJRB Strong Biomarker [1342]
MXD1 OTS5CTHX Strong Altered Expression [501]
MYCBP2 OTHODA1F Strong Genetic Variation [269]
MYL2 OT78PC0C Strong Biomarker [1343]
MYNN OT61R1HP Strong Genetic Variation [1344]
MYO16 OTMS3D8W Strong Genetic Variation [1022]
MYOF OTRFC3IJ Strong Biomarker [1345]
MYRF OTKF6AEB Strong Genetic Variation [135]
MZF1 OTMVZCPW Strong Genetic Variation [224]
NAA10 OTYB9R6I Strong Altered Expression [1346]
NAIP OTLA925F Strong Altered Expression [1347]
NCAPH OTXOS97C Strong Biomarker [1348]
NDC80 OTS7D306 Strong Altered Expression [1349]
NDRG2 OT5L6KD7 Strong Altered Expression [1350]
NEK10 OTN0JAYL Strong Genetic Variation [476]
NEK4 OTOB8366 Strong Biomarker [654]
NELL2 OTS4MJZ7 Strong Altered Expression [547]
NEMF OT9DK06P Strong Biomarker [1351]
NEO1 OTGJ1997 Strong Biomarker [1352]
NEUROD1 OTZQ7QJ2 Strong Biomarker [212]
NFATC1 OT4TMERS Strong Biomarker [1353]
NFATC2 OTK5T6HZ Strong Biomarker [1354]
NHLRC2 OTY4HPWB Strong Biomarker [1355]
NIBAN2 OTVDQSPI Strong Biomarker [1356]
NID1 OTKLBLS6 Strong Posttranslational Modification [1357]
NIT2 OTC1RAH3 Strong Biomarker [1358]
NLRP12 OTGR132Z Strong Biomarker [1359]
NLRP5 OTLU1YML Strong Altered Expression [1360]
NLRP6 OTEREN4W Strong Biomarker [1361]
NME4 OT2JTT42 Strong Biomarker [1362]
NME6 OTJNKOFA Strong Biomarker [1363]
NME7 OTYMBK3Q Strong Biomarker [1363]
NOB1 OTW0YNSL Strong Biomarker [1364]
NOC2L OTNT7R33 Strong Biomarker [1365]
NOX1 OTZPJQCC Strong Biomarker [1366]
NOX5 OTHTH59G Strong Altered Expression [1367]
NOXO1 OTW29FB4 Strong Biomarker [1368]
NPDC1 OT788NC8 Strong Biomarker [1369]
NPHS1 OT21JD3P Strong Biomarker [146]
NPRL2 OTOB10MO Strong Altered Expression [1370]
NPTX1 OTKVHCV0 Strong Biomarker [308]
NRCAM OT80HHQ2 Strong Altered Expression [1371]
NRDC OTWBBCXO Strong Biomarker [1372]
NRIP1 OTIZOJQV Strong Biomarker [1373]
NTNG1 OTF48IID Strong Posttranslational Modification [1374]
NTS OTPGDNQS Strong Altered Expression [1375]
NUCB2 OTHO6JWN Strong Altered Expression [1376]
NUDT1 OTZSES3W Strong Genetic Variation [1377]
NUSAP1 OT85HIJ5 Strong Biomarker [1378]
NXN OT35N40G Strong Genetic Variation [224]
OAS3 OT6E5FYS Strong Altered Expression [535]
OAZ2 OTV1XSWG Strong Biomarker [1379]
OGA OT7ZBWT1 Strong Altered Expression [1380]
OPN1LW OTFNUZ7O Strong Biomarker [1381]
OR1J2 OTIQTQHU Strong Genetic Variation [1022]
OR7C1 OTQKD84O Strong Biomarker [1382]
ORC6 OTKQN3KP Strong Altered Expression [1383]
OTUB1 OT8WWM9O Strong Biomarker [1384]
OTUD3 OTHUWQHP Strong Biomarker [1385]
PADI2 OTT40K94 Strong Altered Expression [1386]
PAG1 OTFOJUIQ Strong Biomarker [1381]
PAK5 OT32WQGL Strong Altered Expression [1387]
PAK6 OTAHPZTT Strong Altered Expression [1388]
PALD1 OTLGUM8H Strong Altered Expression [1389]
PALLD OTZ2MUJZ Strong Altered Expression [1389]
PARP4 OTXBK59G Strong Biomarker [1390]
PATZ1 OT0X9WGR Strong Altered Expression [1391]
PAX2 OTKP1N8F Strong Altered Expression [1392]
PBX3 OT8WMVM4 Strong Posttranslational Modification [1393]
PCBD2 OTXV0ZD0 Strong Biomarker [846]
PCBP4 OTDLL4NB Strong Biomarker [1381]
PCLAF OTMVIOUU Strong Altered Expression [1394]
PCNX1 OTFP8XHC Strong Genetic Variation [1304]
PCP4 OTM1XXYX Strong Biomarker [294]
PDCD6 OT2YA5M8 Strong Biomarker [1395]
PDIK1L OTISF4KG Strong Biomarker [1396]
PDLIM3 OTVXQC81 Strong Altered Expression [265]
PDRG1 OT8ZMFZE Strong Altered Expression [1397]
PEG3 OTHQW98S Strong Biomarker [1398]
PER3 OTVKYVJA Strong Biomarker [1399]
PES1 OTMZK7XE Strong Genetic Variation [1400]
PGK1 OT6V1ICH Strong Altered Expression [1401]
PHF14 OTZT3GV1 Strong Altered Expression [67]
PHF21B OTU5GLCQ Strong Altered Expression [1402]
PHF5A OTS94JFM Strong Altered Expression [479]
PHGR1 OTY3GTEP Strong Altered Expression [1403]
PHLPP1 OTIFXW8D Strong Biomarker [1404]
PHLPP2 OTXB1OUI Strong Altered Expression [1405]
PIAS4 OTB7SVMZ Strong Altered Expression [1406]
PIGR OT6GLSUL Strong Altered Expression [1407]
PIK3C3 OTLUM9L7 Strong Biomarker [1408]
PIK3R1 OT5BZ1J9 Strong Biomarker [984]
PIK3R2 OTZSUQK5 Strong Biomarker [984]
PITX1 OTA0UN4C Strong Genetic Variation [1409]
PIWIL1 OT7CRGZ3 Strong Biomarker [1410]
PIWIL2 OT1PXQIF Strong Altered Expression [1411]
PIWIL4 OTDA9MY0 Strong Biomarker [1410]
PKHD1 OTAH8SMF Strong Genetic Variation [1412]
PKP2 OTJOVF68 Strong Biomarker [1413]
PLA2G3 OT3K7TMY Strong Biomarker [1414]
PLAA OTZ7NJGA Strong Biomarker [494]
PLCH1 OT6Z1L2E Strong Genetic Variation [1415]
PLD4 OT5I74II Strong Altered Expression [1416]
PLEKHG6 OTZWA27A Strong Genetic Variation [224]
PLS3 OTYBM4PK Strong Genetic Variation [1417]
PMEPA1 OTY8Z9UF Strong Biomarker [1418]
PMS2 OTNLWTMI Strong Altered Expression [1419]
PNKD OT6G9UXN Strong Genetic Variation [225]
PNO1 OT010GIS Strong Biomarker [1309]
PNPLA2 OTR3ERMR Strong Biomarker [943]
PODXL OTPNQXF3 Strong Biomarker [1420]
POGLUT1 OTDX7GZD Strong Biomarker [1421]
POLD1 OTWO4UCJ Strong Altered Expression [777]
POLD3 OTEQEFQ2 Strong Genetic Variation [225]
POLDIP2 OT8SZSJ6 Strong Biomarker [251]
POLE OTFM3MMU Strong Genetic Variation [1422]
POTEF OTV3WXYE Strong Biomarker [1423]
POU2F1 OTK7ELJ0 Strong Genetic Variation [129]
POU5F1B OT0FKQ51 Strong Genetic Variation [225]
PPA1 OTHZK1QB Strong Biomarker [1424]
PPBP OT1FHGQS Strong Biomarker [346]
PPDPF OT4LO2GJ Strong Biomarker [1425]
PPL OTTM4WDO Strong Altered Expression [1426]
PPP1R11 OTSHYPPW Strong Biomarker [532]
PPP1R12C OT9Q86JO Strong Biomarker [984]
PPP1R13B OTC88VQO Strong Biomarker [984]
PPP1R13L OTNCPLWE Strong Biomarker [1427]
PPP1R21 OTWN6N7T Strong Genetic Variation [135]
PPP1R8 OTH5KB2P Strong Altered Expression [1346]
PPP2R1B OTFIHQGD Strong Genetic Variation [1428]
PRAP1 OT48QD82 Strong Altered Expression [1429]
PRC1 OTHD0XS0 Strong Posttranslational Modification [1430]
PRDM1 OTQLSVBS Strong Altered Expression [1431]
PRDM2 OT8L7CGX Strong Genetic Variation [1432]
PRDX1 OTZ3BEC4 Strong Altered Expression [1433]
PRDX3 OTLB2WEU Strong Biomarker [1434]
PREX1 OTUTPVA9 Strong Genetic Variation [135]
PRKAA1 OT7TNF0L Strong Altered Expression [1435]
PRKAA2 OTU1KZPV Strong Biomarker [1436]
PRKAB1 OT1OG4QZ Strong Altered Expression [1435]
PRM1 OT6HWA11 Strong Biomarker [1437]
PRMT8 OT3MRK62 Strong Altered Expression [1438]
PROK1 OT8S7RUG Strong Biomarker [596]
PROX1 OT68R6IO Strong Altered Expression [1439]
PRPF31 OTSJ0Z1Y Strong Altered Expression [1440]
PRR14 OTZMIMOK Strong Altered Expression [1441]
PRRT1 OTN0YIS3 Strong Biomarker [1442]
PRRX2 OT8UR4AU Strong Biomarker [1443]
PRSS22 OTANEFGM Strong Biomarker [1444]
PRSS55 OTXXWI5Y Strong Biomarker [1098]
PSD3 OTTN9B9O Strong Biomarker [1445]
PSMD9 OT6Y5CC3 Strong Biomarker [1125]
PSME3 OTSTC4YY Strong Altered Expression [1446]
PSMG1 OTZ5I6UM Strong Biomarker [245]
PTHLH OTI1JF13 Strong Altered Expression [1447]
PTPN12 OT5WA666 Strong Genetic Variation [1448]
PTPRG OT9N2WOF Strong Biomarker [1449]
PTPRM OTCEL6PN Strong Posttranslational Modification [1450]
PTPRT OTV5TXNN Strong Biomarker [1451]
PTPRU OTHDO0QG Strong Biomarker [744]
PTTG1 OTIMYS4W Strong Biomarker [1452]
PUF60 OTG90DYF Strong Biomarker [1052]
PVR OT3N91T7 Strong Altered Expression [1453]
PXN OTVMMUOF Strong Altered Expression [1454]
QRSL1 OTJDU2UG Strong Biomarker [1455]
RAB11A OTC4FW0J Strong Biomarker [1456]
RAB25 OTW0W6NP Strong Biomarker [1457]
RAB43 OTVCSILI Strong Genetic Variation [1458]
RABGEF1 OTWC3Z3R Strong Altered Expression [1459]
RAC2 OTAOHFNH Strong Altered Expression [1460]
RAD50 OTYMU9G1 Strong Altered Expression [1461]
RAD51B OTCJVRMY Strong Genetic Variation [518]
RAG1 OTV131E4 Strong Biomarker [1249]
RALY OT78NNWY Strong Genetic Variation [476]
RAN OT2TER5M Strong Genetic Variation [1462]
RANBP2 OTFG5CVF Strong Altered Expression [597]
RANBP3 OTI8ESC3 Strong Altered Expression [1444]
RAP1A OT5RH6TI Strong Altered Expression [1459]
RAPGEF1 OTZ0TBN1 Strong Genetic Variation [1463]
RAPGEF5 OT53VS75 Strong Biomarker [1464]
RARRES1 OTETUPP5 Strong Biomarker [1318]
RASAL1 OTAHUNN7 Strong Biomarker [1465]
RASGRF2 OT67DAGF Strong Altered Expression [1466]
RBBP6 OTTVG4HU Strong Biomarker [1467]
RBBP8 OTRHJ3GI Strong Genetic Variation [1468]
RBFOX2 OTXY1WVH Strong Biomarker [1469]
RBM14 OTO9GMBD Strong Genetic Variation [625]
RBM38 OTPO8EXU Strong Altered Expression [1278]
RBMS3 OTFSC9MR Strong Biomarker [1309]
RBP7 OT0J3CPT Strong Biomarker [1470]
RDX OTNSYUN6 Strong Biomarker [1335]
RECQL5 OTVZMP1Q Strong Biomarker [1471]
REEP5 OTZU4TJI Strong Biomarker [1472]
REG1A OTMHUH1D Strong Biomarker [744]
REG1B OTSC2133 Strong Altered Expression [901]
REM1 OTUXL0HC Strong Biomarker [1473]
RETREG3 OTEUQ2MI Strong Genetic Variation [675]
REV3L OT0OP8EJ Strong Altered Expression [1474]
RFC1 OT3L5PK3 Strong Biomarker [1475]
RFC2 OTJ9N6BD Strong Biomarker [1476]
RGCC OTYJMLWM Strong Altered Expression [1477]
RGN OTD04KB1 Strong Biomarker [1478]
RGS19 OTBIELDO Strong Biomarker [1479]
RHBDF1 OTCQ7UDS Strong Biomarker [1480]
RHOBTB1 OTGE8K45 Strong Biomarker [1481]
RHOJ OTWI65OA Strong Biomarker [294]
RHPN2 OTTYWMF6 Strong Genetic Variation [225]
RIN1 OTPBROUD Strong Genetic Variation [1482]
RIOK1 OT1OS3H3 Strong Altered Expression [1483]
RIOX2 OT2YFPI2 Strong Altered Expression [1484]
RIPK3 OTL1D484 Strong Altered Expression [1485]
RIPOR3 OTHZ4RKK Strong Genetic Variation [224]
RITA1 OTUH8IPS Strong Biomarker [514]
RMC1 OT7K8MTJ Strong Biomarker [1486]
RMDN1 OTE1NB6U Strong Altered Expression [700]
RMDN2 OTK5WSFI Strong Altered Expression [700]
RMDN3 OTKO7AUM Strong Altered Expression [700]
RNF14 OTWX0D0H Strong Biomarker [1487]
RNF19A OTKWCV80 Strong Biomarker [251]
RNF4 OTCMXQRE Strong Genetic Variation [1022]
RNGTT OT59E0KX Strong Genetic Variation [675]
ROBO3 OTPVG40S Strong Biomarker [354]
RPE OT0XT3JU Strong Biomarker [1488]
RPIA OT805SMH Strong Altered Expression [1489]
RPL29 OTUFIBJL Strong Altered Expression [1490]
RPL3 OTX6VXLB Strong Altered Expression [1491]
RPL30 OTLQVY1Z Strong Biomarker [1469]
RPL37 OTB6SDZ1 Strong Altered Expression [1492]
RPLP1 OT7B0SIB Strong Altered Expression [1493]
RPRD1B OTB41D5K Strong Altered Expression [1494]
RPS18 OTFO45UM Strong Biomarker [1495]
RPS20 OTI8052R Strong Genetic Variation [1496]
RPS24 OTSNKIL5 Strong Biomarker [1497]
RPS27 OTFXKY7P Strong Biomarker [453]
RPS27A OTIIGGZ2 Strong Altered Expression [1498]
RPS6 OTT4D1LN Strong Altered Expression [67]
RRS1 OTTNCZN6 Strong Biomarker [1499]
RTEL1 OTI3PJCT Strong Genetic Variation [224]
RTKN2 OTV2AXQM Strong Biomarker [1500]
RUNX1T1 OT30DED5 Strong Biomarker [1501]
RUVBL1 OTWV19L7 Strong Altered Expression [1502]
RUVBL2 OTGWJ4T4 Strong Biomarker [384]
RYR3 OT4EHIP4 Strong Genetic Variation [1503]
SAA2 OTYAVJWG Strong Biomarker [126]
SALL1 OTYYZGLH Strong Biomarker [1442]
SALL4 OTC08PR5 Strong Biomarker [1504]
SAMD9 OTDG48P0 Strong Altered Expression [1505]
SAMHD1 OTBCIBC7 Strong Genetic Variation [1506]
SART3 OTC1AM7S Strong Altered Expression [535]
SASS6 OT1V8H40 Strong Altered Expression [1507]
SBF2 OTBB8NO8 Strong Genetic Variation [55]
SCAF11 OTX59D0X Strong Biomarker [1204]
SCAF8 OTSCFMK3 Strong Genetic Variation [675]
SCGB2A1 OT9L87U9 Strong Altered Expression [1508]
SCRN1 OTELM5C2 Strong Altered Expression [1509]
SDAD1 OTP4468N Strong Biomarker [1510]
SDC4 OTKUVUGZ Strong Altered Expression [1511]
SDCBP OTS3NCC5 Strong Biomarker [1512]
SDF4 OTQ7WFYW Strong Biomarker [1066]
SEC14L2 OTJST64D Strong Biomarker [1513]
SELENOF OT2JFB3S Strong Genetic Variation [733]
SELENOP OT02B8IR Strong Altered Expression [1514]
SEMA3F OTQFMS8S Strong Biomarker [1515]
SEMA5A OTUOIOJV Strong Biomarker [1516]
SEPTIN9 OT1VMRFQ Strong Biomarker [1517]
SERPINA3 OT9BP2S0 Strong Biomarker [1518]
SERPINB2 OT72QLZB Strong Biomarker [1519]
SETBP1 OTKGCOSR Strong Biomarker [1520]
SFN OTLJCZ1U Strong Altered Expression [1521]
SFPQ OTLCIAPJ Strong Biomarker [1522]
SGK3 OTQ6QO99 Strong Biomarker [1523]
SGMS2 OT3NHO99 Strong Biomarker [1524]
SGSM3 OTIB1P8A Strong Biomarker [1525]
SH3KBP1 OTIUA60B Strong Biomarker [294]
SH3PXD2B OTAOMCDJ Strong Biomarker [1526]
SHC1 OT1J5IRN Strong Altered Expression [1527]
SHMT1 OTIINA3J Strong Genetic Variation [1528]
SHROOM2 OTZ2FJ7Q Strong Genetic Variation [55]
SIAH1 OT29A838 Strong Biomarker [1529]
SIGLEC7 OTNDLURR Strong Biomarker [1530]
SIM2 OT0QWHK4 Strong Altered Expression [1531]
SIVA1 OTDT0XZK Strong Altered Expression [1532]
SLC12A9 OTR7VRAK Strong Altered Expression [1533]
SLC2A4RG OTW3LX8D Strong Genetic Variation [1534]
SLC66A1 OTUM63MK Strong Biomarker [1423]
SLFN12 OTTBXM25 Strong Biomarker [1535]
SLPI OTUNFUU8 Strong Altered Expression [265]
SMARCA1 OT0Y6PTU Strong Biomarker [1536]
SMG1 OTTS3SXE Strong Biomarker [1537]
SMOC2 OTK1EQ49 Strong Biomarker [1538]
SNAI1 OTDPYAMC Strong Altered Expression [1539]
SND1 OTT734JN Strong Altered Expression [1540]
SNED1 OTBQVXY5 Strong Altered Expression [1541]
SNRK OTX0OPHO Strong Biomarker [1542]
SNX1 OTXQSJ1J Strong Altered Expression [1543]
SNX9 OTLNQ0ZM Strong Altered Expression [1544]
SOCS2 OTBPNKJQ Strong Altered Expression [1545]
SOX12 OT93P8C9 Strong Biomarker [1546]
SOX30 OTGT38E3 Strong Altered Expression [1547]
SOX4 OTSS40SS Strong Biomarker [105]
SOX9 OTVDJFGN Strong Altered Expression [939]
SP4 OTWB30IZ Strong Altered Expression [1548]
SPINK1 OTSUVAL2 Strong Altered Expression [1549]
SPON2 OTE7JLNM Strong Biomarker [1550]
SPPL3 OT2HLJF6 Strong Biomarker [1252]
SPRY2 OTH0CRCZ Strong Biomarker [1551]
SPSB2 OT7ZVT8R Strong Genetic Variation [348]
SPTAN1 OT6VY3A3 Strong Altered Expression [1552]
SPZ1 OTQH8HJ5 Strong Biomarker [1098]
SRPRB OTUUFHQS Strong Altered Expression [1460]
SRPX2 OT6A63TX Strong Biomarker [1553]
SRRM2 OTSIMMC9 Strong Biomarker [1309]
SRSF1 OTF61HOV Strong Altered Expression [880]
SRSF11 OTZSV6CZ Strong Altered Expression [162]
SRSF3 OTOFT707 Strong Altered Expression [1554]
SRSF6 OTGLOSYE Strong Biomarker [1555]
SSBP1 OTH2PZWH Strong Biomarker [1556]
SSX2 OT2Z6RLL Strong Biomarker [1557]
ST13 OTNML6UP Strong Biomarker [245]
ST6GALNAC1 OT3JQD99 Strong Altered Expression [107]
ST7 OTZG8RC6 Strong Genetic Variation [1558]
STARD13 OTB4U1HY Strong Biomarker [1559]
STARD3 OTSTC5B5 Strong Biomarker [1369]
STAT2 OTO9G2RZ Strong Biomarker [1560]
STEAP4 OTFTLAEZ Strong Biomarker [1561]
STING1 OTDAP4G0 Strong Biomarker [1006]
STK3 OTLNSCQD Strong Altered Expression [1562]
SUFU OT0IRYG1 Strong Biomarker [1563]
SUGP1 OT7W0EB8 Strong Altered Expression [1564]
SUMO1 OTJFD4P5 Strong Biomarker [1565]
SUZ12 OT655XF8 Strong Altered Expression [1566]
SYBU OT3FQV7N Strong Altered Expression [700]
SYCE1L OTXU44F3 Strong Altered Expression [1280]
SYMPK OTYAUDXV Strong Genetic Variation [1211]
SYNJ2 OTLRHXP1 Strong Biomarker [1567]
TADA2A OTXUMEL9 Strong Biomarker [947]
TANC1 OTF6TZ8E Strong Genetic Variation [224]
TAPBP OTL81AVZ Strong Biomarker [1568]
TAS2R16 OT67HLNS Strong Genetic Variation [1569]
TBPL1 OT4I143E Strong Altered Expression [676]
TBPL2 OTDEC1KO Strong Altered Expression [1570]
TBX3 OTM64N7K Strong Genetic Variation [1571]
TBX5 OT70PISV Strong Biomarker [1572]
TCERG1L OTSBSCLF Strong Biomarker [1573]
TCF19 OT7NKLF9 Strong Biomarker [294]
TCF4 OTB9ASTK Strong Biomarker [1574]
TCF7 OT1ID822 Strong Biomarker [1575]
TCHP OTVDMHSY Strong Biomarker [1576]
TCIM OTARUXQF Strong Biomarker [1577]
TCTN1 OTG5KEV8 Strong Biomarker [1578]
TDRD6 OTW2UL4V Strong Altered Expression [1278]
TEKT5 OTZ5OUHY Strong Altered Expression [1579]
TENM1 OTSKSU4V Strong Biomarker [1580]
TENM3 OTWY13GR Strong Biomarker [486]
TERF2IP OT3M5P3G Strong Altered Expression [1459]
TET1 OTZDHT1D Strong Biomarker [1581]
TFAM OTXXV5V7 Strong Biomarker [1582]
TFEB OTJUJJQY Strong Genetic Variation [55]
TFF2 OTRXB19X Strong Genetic Variation [1583]
TFF3 OTJJDRTU Strong Altered Expression [678]
TFPI2 OTZCRWOR Strong Biomarker [467]
TGFBR3 OTQOOUC4 Strong Biomarker [1584]
THAP11 OTEMWLZ0 Strong Biomarker [1222]
THBS2 OTXET551 Strong Biomarker [1585]
TIA1 OTGPN3P8 Strong Altered Expression [1586]
TICAM2 OTK7GIJ5 Strong Biomarker [1125]
TIMELESS OTD8DCBJ Strong Biomarker [983]
TIMP1 OTOXC51H Strong Altered Expression [1587]
TKTL2 OTULV5TA Strong Biomarker [684]
TLE5 OTEH0BFG Strong Biomarker [1588]
TM4SF1 OTY0ECQN Strong Biomarker [1589]
TM7SF2 OTILU5S7 Strong Biomarker [256]
TMBIM1 OTE47B57 Strong Genetic Variation [225]
TMED7 OTONO8E6 Strong Biomarker [1125]
TMEFF2 OT1WZ2QO Strong Posttranslational Modification [1590]
TMEM147 OTMKZ4PV Strong Biomarker [1591]
TMEM208 OTMGH9OA Strong Biomarker [1423]
TMEM258 OTXSDU14 Strong Genetic Variation [135]
TMEM37 OT317PEL Strong Biomarker [896]
TMEM69 OTXBBENK Strong Altered Expression [1444]
TMEM8B OTJZWPS6 Strong Biomarker [1592]
TMIGD2 OTWWAHTV Strong Altered Expression [1593]
TMPRSS4 OTCCGY2K Strong Altered Expression [1594]
TMTC1 OTZ7NW96 Strong Genetic Variation [675]
TNFAIP8 OT1G9297 Strong Biomarker [1595]
TNFAIP8L2 OTII0RM0 Strong Altered Expression [1596]
TNFRSF10D OTOSRDJT Strong Altered Expression [1597]
TNFRSF6B OTKAN9G7 Strong Altered Expression [1598]
TNFSF9 OTV9L89D Strong Biomarker [1599]
TNS3 OTPG2D8Z Strong Genetic Variation [55]
TOB1 OTNW949D Strong Biomarker [1600]
TOX2 OT7RZRVK Strong Genetic Variation [224]
TP53I3 OTSCM68G Strong Biomarker [1331]
TP53INP1 OT2363Z9 Strong Genetic Variation [625]
TP53RK OTARRZAB Strong Altered Expression [1601]
TP63 OT0WOOKQ Strong Biomarker [882]
TPM2 OTA1L0P8 Strong Posttranslational Modification [1602]
TPM4 OTN4YLYR Strong Biomarker [1603]
TRAF1 OTTLM5RU Strong Biomarker [1604]
TRAF2 OT1MEZZN Strong Biomarker [1605]
TRERF1 OTA7UQF1 Strong Biomarker [1606]
TRIM11 OTMD6IM2 Strong Biomarker [1607]
TRIM15 OTNYAKP6 Strong Biomarker [1608]
TRIM23 OTVIGJ4T Strong Altered Expression [1346]
TRPS1 OT7XPPEL Strong Biomarker [1609]
TRRAP OT68OI2Y Strong Biomarker [1610]
TSACC OT3QW6PH Strong Genetic Variation [625]
TSGA10 OTIF1O1T Strong Altered Expression [1611]
TSPAN1 OTZQPIYK Strong Biomarker [1612]
TSPAN8 OT1F68WQ Strong Biomarker [1613]
TSTD1 OT5DMKFX Strong Biomarker [176]
TTC22 OTFNNLI1 Strong Biomarker [1614]
ARMC8 OTNAXGM7 Definitive Biomarker [1615]
BRD8 OTIKS3PC Definitive Altered Expression [610]
CALD1 OTNJKJ6Q Definitive Altered Expression [1616]
CDK5RAP3 OTC0Q2QS Definitive Genetic Variation [1617]
CNNM4 OTUXJRM1 Definitive Altered Expression [1618]
CRIP1 OT0EICG3 Definitive Altered Expression [1619]
EPS8 OTZ6ES6V Definitive Altered Expression [1620]
FBN2 OT3KYJQL Definitive Biomarker [1621]
FOXD3 OTXYV6GO Definitive Biomarker [1622]
GATA5 OTO81B63 Definitive Biomarker [1623]
HECW2 OTP2IN12 Definitive Altered Expression [1624]
HNRNPU OTLQN1E2 Definitive Altered Expression [610]
IGSF1 OT3XD6U2 Definitive Altered Expression [610]
KRT23 OTQW6UAG Definitive Biomarker [1625]
MMRN1 OT7ZNYHT Definitive Genetic Variation [1626]
MYO1A OTS80FOD Definitive Posttranslational Modification [1627]
NAA25 OTS3QVF1 Definitive Altered Expression [610]
NSUN5 OTBN7RS8 Definitive Altered Expression [610]
PAEP OTQA0NV4 Definitive Biomarker [1628]
PRPF40A OT6EXJZN Definitive Genetic Variation [1629]
REEP6 OTY4FPO8 Definitive Genetic Variation [1630]
SPAG9 OT45AHMB Definitive Biomarker [1631]
ST6GAL1 OT7US3NO Definitive Biomarker [1632]
STIM2 OTYNXAW0 Definitive Altered Expression [1633]
TMEM132D OTV6I4Z0 Definitive Biomarker [1634]
TRA2B OTZYQW52 Definitive Biomarker [1635]
TRIM21 OTA4UJCF Definitive Altered Expression [295]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1204 DOT(s)

References

1 Immunity feedback and clinical outcome in colon cancer patients undergoing chemoimmunotherapy with gemcitabine + FOLFOX followed by subcutaneous granulocyte macrophage colony-stimulating factor and aldesleukin (GOLFIG-1 Trial). Clin Cancer Res. 2008 Jul 1;14(13):4192-9.
2 Aspirin FDA Label
3 ClinicalTrials.gov (NCT03827044) Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer (POLEM). U.S. National Institutes of Health.
4 Colon cancer. Crit Rev Oncol Hematol. 2010 May;74(2):106-33.
5 Bortezomib FDA Label
6 Capecitabine FDA Label
7 Celecoxib FDA Label
8 Citalopram FDA Label
9 Eflornithine FDA Label
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4920).
11 Everolimus FDA Label
12 Floxuridine FDA Label
13 Fludarabine FDA Label
14 Fluorouracil FDA Label
15 Gefitinib FDA Label
16 Gemcitabine FDA Label
17 Hydroxychloroquine FDA Label
18 Irinotecan FDA Label
19 Lenalidomide FDA Label
20 Leucovorin FDA Label
21 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7210).
22 Levoleucovorin FDA Label
23 Mitomycin FDA Label
24 Oxaliplatin FDA Label
25 Rosuvastatin FDA Label
26 Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators. J Med Chem. 1998 Nov 19;41(24):4800-18.
27 ClinicalTrials.gov (NCT03157128) A Study of LOXO-292 in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001). U.S. National Institutes of Health.
28 Sulindac FDA Label
29 Thalidomide FDA Label
30 Trifluridine FDA Label
31 Design and synthesis of bile acid derivatives and their activity against colon cancer. RSC Med Chem. 2022 Aug 19;13(11):1391-1409.
32 Vidarabine FDA Label
33 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
34 ClinicalTrials.gov (NCT03013712) A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer
35 Cancer stem cell (CSC) inhibitors: a review of recent patents (2012-2015).Expert Opin Ther Pat. 2017 Jul;27(7):753-761.
36 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024569)
37 Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease. Nat Rev Drug Discov. 2021 Apr;20(4):265-286.
38 Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J Clin Invest. 2009 Dec;119(12):3613-25.
39 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002548)
40 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
41 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
42 Prognostic implication of ABC transporters and cancer stem cell markers in patients with stage III colon cancer receiving adjuvant FOLFOX-4 chemotherapy.Oncol Lett. 2019 Jun;17(6):5572-5580. doi: 10.3892/ol.2019.10234. Epub 2019 Apr 9.
43 Effect of overexpression of - and -actin isoforms on actin cytoskeleton organization and migration of human colon cancer cells.Histochem Cell Biol. 2014 Sep;142(3):307-22. doi: 10.1007/s00418-014-1199-9. Epub 2014 Feb 28.
44 Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells.Hum Pathol. 2010 Nov;41(11):1550-7. doi: 10.1016/j.humpath.2010.04.008.
45 Aldo-Keto Reductases: Multifunctional Proteins as Therapeutic Targets in Diabetes and Inflammatory Disease.Adv Exp Med Biol. 2018;1032:173-202. doi: 10.1007/978-3-319-98788-0_13.
46 Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers. Nat Commun. 2018 Sep 26;9(1):3931.
47 Immunohistochemistry for annexin A10 can distinguish sporadic from Lynch syndrome-associated microsatellite-unstable colorectal carcinoma.Am J Surg Pathol. 2014 Apr;38(4):518-25. doi: 10.1097/PAS.0000000000000148.
48 Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration.Sci Rep. 2019 Sep 2;9(1):12635. doi: 10.1038/s41598-019-49045-9.
49 Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.Oncotarget. 2018 Mar 30;9(24):17066-17077. doi: 10.18632/oncotarget.24899. eCollection 2018 Mar 30.
50 Silica Nanoparticles Provoke Cell Death Independent of p53 and BAX in Human Colon Cancer Cells.Nanomaterials (Basel). 2019 Aug 16;9(8):1172. doi: 10.3390/nano9081172.
51 Biglycan promotes the chemotherapy resistance of colon cancer by activating NF-B signal transduction.Mol Cell Biochem. 2018 Dec;449(1-2):285-294. doi: 10.1007/s11010-018-3365-1. Epub 2018 May 14.
52 BRIP-1 germline mutation and its role in colon cancer: presentation of two case reports and review of literature.BMC Med Genet. 2019 May 7;20(1):75. doi: 10.1186/s12881-019-0812-0.
53 Enhanced expression of cholecystokinin-2 receptor promotes the progression of colon cancer through activation of focal adhesion kinase.Int J Cancer. 2006 Dec 15;119(12):2724-32. doi: 10.1002/ijc.22207.
54 Molecular imaging of T cell co-regulator factor B7-H3 with (89)Zr-DS-5573a.Theranostics. 2018 Jul 30;8(15):4199-4209. doi: 10.7150/thno.25575. eCollection 2018.
55 Association analyses identify 31 new risk loci for colorectal cancer susceptibility.Nat Commun. 2019 May 14;10(1):2154. doi: 10.1038/s41467-019-09775-w.
56 Genetic polymorphism 609C>T in NAD(P)H:quinone oxidoreductase 1 enhances the risk of proximal colon cancer.J Hum Genet. 2014 Jul;59(7):381-6. doi: 10.1038/jhg.2014.38. Epub 2014 May 15.
57 The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis.JCI Insight. 2018 Sep 20;3(18):e97506. doi: 10.1172/jci.insight.97506. eCollection 2018 Sep 20.
58 Interleukin genes and associations with colon and rectal cancer risk and overall survival.Int J Cancer. 2013 Feb 15;132(4):905-15. doi: 10.1002/ijc.27660. Epub 2012 Jun 26.
59 Non-platelet-derived CXCL4 differentially regulates cytotoxic and regulatory T cells through CXCR3 to suppress the immune response to colon cancer.Cancer Lett. 2019 Feb 28;443:1-12. doi: 10.1016/j.canlet.2018.11.017. Epub 2018 Nov 24.
60 Colonic vitamin D metabolism: implications for the pathogenesis of inflammatory bowel disease and colorectal cancer.Mol Cell Endocrinol. 2011 Dec 5;347(1-2):70-9. doi: 10.1016/j.mce.2011.07.022. Epub 2011 Jul 27.
61 Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.Cancer Res. 2006 Aug 1;66(15):7571-7. doi: 10.1158/0008-5472.CAN-06-1067.
62 Vitamin D enhances the efficacy of irinotecan through miR-627-mediated inhibition of intratumoral drug metabolism. Mol Cancer Ther. 2016 Sep;15(9):2086-95.
63 The DEAD box protein p68: a novel coactivator of Stat3 in mediating oncogenesis.Oncogene. 2017 Jun 1;36(22):3080-3093. doi: 10.1038/onc.2016.449. Epub 2016 Dec 12.
64 Dicer regulates non-homologous end joining and is associated with chemosensitivity in colon cancer patients.Carcinogenesis. 2017 Sep 1;38(9):873-882. doi: 10.1093/carcin/bgx059.
65 5-Aza-CdR Regulates RASSF1A By Inhibiting DNMT1 To Affect Colon Cancer Cell Proliferation, Migration And Apoptosis.Cancer Manag Res. 2019 Nov 8;11:9517-9528. doi: 10.2147/CMAR.S229726. eCollection 2019.
66 Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells.Sci Rep. 2019 Mar 1;9(1):3210. doi: 10.1038/s41598-019-39547-x.
67 Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.Oncotarget. 2019 Mar 15;10(22):2136-2150. doi: 10.18632/oncotarget.26669. eCollection 2019 Mar 15.
68 The Diagnostic Significance of PDGF, EphA7, CCR5, and CCL5 Levels in Colorectal Cancer.Biomolecules. 2019 Sep 9;9(9):464. doi: 10.3390/biom9090464.
69 Loss-of-function uORF mutations in human malignancies.Sci Rep. 2018 Feb 5;8(1):2395. doi: 10.1038/s41598-018-19201-8.
70 Chimeric Antigen Receptor-modified T Cells Repressed Solid Tumors and Their Relapse in an Established Patient-derived Colon Carcinoma Xenograft Model.J Immunother. 2019 Feb/Mar;42(2):33-42. doi: 10.1097/CJI.0000000000000251.
71 Estrogen Receptor as a Prognostic Marker of Tumor Progression in Colorectal Cancer with Familial Adenomatous Polyposis and Sporadic Polyps.Pathol Oncol Res. 2018 Jul;24(3):533-540. doi: 10.1007/s12253-017-0268-5. Epub 2017 Jul 5.
72 Identification of Estrogen-Related Receptor Agonists in the Tox21 Compound Library.Endocrinology. 2018 Feb 1;159(2):744-753. doi: 10.1210/en.2017-00658.
73 Proteomic characterization of peroxisome proliferator-activated receptor- (PPAR) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype.Mol Oncol. 2016 Oct;10(8):1344-62. doi: 10.1016/j.molonc.2016.07.006. Epub 2016 Jul 25.
74 Factor VIIa regulates the expression of caspase-3, MMP-9, and CD44 in SW620 colon cancer cells involving PAR2/MAPKs/NF-B signaling pathways.Cancer Invest. 2013 Jan;31(1):7-16. doi: 10.3109/07357907.2012.743556. Epub 2012 Nov 21.
75 Fibroblast growth factor 18 promotes proliferation and migration of H460 cells via the ERK and p38 signaling pathways.Oncol Rep. 2017 Feb;37(2):1235-1242. doi: 10.3892/or.2016.5301. Epub 2016 Dec 7.
76 FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7.Cancer Sci. 2015 Oct;106(10):1278-87. doi: 10.1111/cas.12745. Epub 2015 Sep 4.
77 Dual targeting system by supramolecular complex of folate-conjugated methyl--cyclodextrin with adamantane-grafted hyaluronic acid for the treatment of colorectal cancer.Int J Biol Macromol. 2018 Jul 1;113:386-394. doi: 10.1016/j.ijbiomac.2018.02.149. Epub 2018 Feb 24.
78 Down-regulation of growth arrest DNA damage-inducible gene 45beta expression is associated with human hepatocellular carcinoma. Am J Pathol. 2003 Jun;162(6):1961-74.
79 A review of gigaxonin mutations in giant axonal neuropathy (GAN) and cancer.Hum Genet. 2016 Jul;135(7):675-84. doi: 10.1007/s00439-016-1659-5. Epub 2016 Mar 29.
80 Apoptotic Effects of Drug Targeting Conjugates Containing Different GnRH Analogs on Colon Carcinoma Cells.Int J Mol Sci. 2019 Sep 8;20(18):4421. doi: 10.3390/ijms20184421.
81 Identification of recurrent fusion genes across multiple cancer types.Sci Rep. 2019 Jan 31;9(1):1074. doi: 10.1038/s41598-019-38550-6.
82 Increased frequency of gastrin-releasing peptide receptor gene mutations during colon-adenocarcinoma progression.Mol Carcinog. 2003 May;37(1):5-15. doi: 10.1002/mc.10117.
83 Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial?mesenchymal transition via the AKT/GSK?/Snail signaling pathway.Mol Med Rep. 2019 Sep;20(3):2783-2795. doi: 10.3892/mmr.2019.10528. Epub 2019 Jul 25.
84 Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients.J Immunother Cancer. 2019 Apr 23;7(1):104. doi: 10.1186/s40425-019-0576-2.
85 Effect of butyrate and Lactobacillus GG on a butyrate receptor and transporter during Campylobacter jejuni exposure.FEMS Microbiol Lett. 2017 Mar 1;364(6):fnx046. doi: 10.1093/femsle/fnx046.
86 Sumoylation of HDAC2 promotes NF-B-dependent gene expression.Oncotarget. 2015 Mar 30;6(9):7123-35. doi: 10.18632/oncotarget.3344.
87 Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.BMC Cancer. 2011 Feb 1;11:51. doi: 10.1186/1471-2407-11-51.
88 Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth.Cancer Gene Ther. 2020 Apr;27(3-4):235-245. doi: 10.1038/s41417-019-0089-7. Epub 2019 Mar 1.
89 Downregulated IGFBP7 facilitates liver metastasis by modulating epithelialmesenchymal transition in colon cancer.Oncol Rep. 2019 Nov;42(5):1935-1945. doi: 10.3892/or.2019.7303. Epub 2019 Sep 6.
90 Interleukin-1 receptor antagonist inhibits angiogenesis via blockage IL-1/PI3K/NF- pathway in human colon cancer cell.Cancer Manag Res. 2017 Oct 9;9:481-493. doi: 10.2147/CMAR.S147699. eCollection 2017.
91 IL-23 in inflammatory bowel diseases and colon cancer.Cytokine Growth Factor Rev. 2019 Feb;45:1-8. doi: 10.1016/j.cytogfr.2018.12.002. Epub 2018 Dec 12.
92 Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival.Carcinogenesis. 2011 Nov;32(11):1660-7. doi: 10.1093/carcin/bgr189. Epub 2011 Aug 22.
93 Role of microRNA 30a targeting insulin receptor substrate 2 in colorectal tumorigenesis.Mol Cell Biol. 2015 Mar;35(6):988-1000. doi: 10.1128/MCB.01242-14. Epub 2015 Jan 12.
94 Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia.PLoS One. 2017 Nov 9;12(11):e0187200. doi: 10.1371/journal.pone.0187200. eCollection 2017.
95 n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer.Nutrients. 2019 Jan 15;11(1):171. doi: 10.3390/nu11010171.
96 p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes.Nucleic Acids Res. 2017 May 19;45(9):5086-5099. doi: 10.1093/nar/gkx075.
97 Co-inhibitory T cell receptor KLRG1: human cancer expression and efficacy of neutralization in murine cancer models.Oncotarget. 2019 Feb 15;10(14):1399-1406. doi: 10.18632/oncotarget.26659. eCollection 2019 Feb 15.
98 Leptin induces SIRT1 expression through activation of NF-E2-related factor 2: Implications for obesity-associated colon carcinogenesis.Biochem Pharmacol. 2018 Jul;153:282-291. doi: 10.1016/j.bcp.2018.02.001. Epub 2018 Feb 7.
99 Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways.Biochem Cell Biol. 2017 Feb;95(1):99-109. doi: 10.1139/bcb-2016-0094. Epub 2016 Nov 30.
100 MAP kinase genes and colon and rectal cancer.Carcinogenesis. 2012 Dec;33(12):2398-408. doi: 10.1093/carcin/bgs305. Epub 2012 Oct 1.
101 MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism.Oncotarget. 2016 Jun 7;7(23):34322-40. doi: 10.18632/oncotarget.9107.
102 Targeting M3 Muscarinic Receptors for Colon Cancer Therapy.Curr Mol Pharmacol. 2018;11(3):184-190. doi: 10.2174/1874467211666180119115828.
103 Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer.J Biol Chem. 2019 May 24;294(21):8529-8542. doi: 10.1074/jbc.RA118.004361. Epub 2019 Apr 9.
104 Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins.BMC Cancer. 2018 Aug 10;18(1):809. doi: 10.1186/s12885-018-4704-z.
105 A TGF--MTA1-SOX4-EZH2 signaling axis drives epithelial-mesenchymal transition in tumor metastasis.Oncogene. 2020 Mar;39(10):2125-2139. doi: 10.1038/s41388-019-1132-8. Epub 2019 Dec 6.
106 AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model.Oncotarget. 2016 Dec 6;7(49):81634-81644. doi: 10.18632/oncotarget.13155.
107 Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer.Cancer Immunol Res. 2020 Feb;8(2):167-178. doi: 10.1158/2326-6066.CIR-19-0514. Epub 2019 Dec 12.
108 MUC17, a novel membrane-tethered mucin.Biochem Biophys Res Commun. 2002 Mar 1;291(3):466-75. doi: 10.1006/bbrc.2002.6475.
109 Contribution of drugs acting on the TLRs/MyD88 signaling pathway on colitis-associated cancer.Pharmazie. 2018 Jul 1;73(7):363-368. doi: 10.1691/ph.2018.8388.
110 The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans.Acta Histochem. 2012 Dec;114(8):827-35. doi: 10.1016/j.acthis.2012.02.004. Epub 2012 Mar 13.
111 Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation.Mol Cancer. 2010 Oct 15;9:276. doi: 10.1186/1476-4598-9-276.
112 Enhanced tumor retention of NTSR1-targeted agents by employing a hydrophilic cysteine cathepsin inhibitor.Eur J Med Chem. 2019 Sep 1;177:386-400. doi: 10.1016/j.ejmech.2019.05.068. Epub 2019 May 25.
113 Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.Mol Cancer Res. 2013 Feb;11(2):109-21. doi: 10.1158/1541-7786.MCR-12-0466. Epub 2012 Dec 10.
114 Eupafolin Suppresses Esophagus Cancer Growth by Targeting T-LAK Cell-Originated Protein Kinase.Front Pharmacol. 2019 Oct 22;10:1248. doi: 10.3389/fphar.2019.01248. eCollection 2019.
115 The plasminogen activator inhibitor system in colon cancer cell lines is influenced by the CO2 pneumoperitoneum.Int J Colorectal Dis. 2011 Jan;26(1):37-43. doi: 10.1007/s00384-010-1062-y. Epub 2010 Oct 8.
116 The Roles of EP4 Prostanoid Receptors in Cancer Malignancy Signaling.Biol Pharm Bull. 2016;39(2):149-55. doi: 10.1248/bpb.b15-00840.
117 MicroRNA? suppresses human colon cancer invasion and proliferation by targeting the expression of focal adhesion kinase.Mol Med Rep. 2016 Feb;13(2):1297-303. doi: 10.3892/mmr.2015.4643. Epub 2015 Dec 4.
118 Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer.Mol Cancer Res. 2016 Jun;14(6):563-73. doi: 10.1158/1541-7786.MCR-15-0450. Epub 2016 Mar 16.
119 Therapeutic silence of pleiotrophin by targeted delivery of siRNA and its effect on the inhibition of tumor growth and metastasis.PLoS One. 2017 May 31;12(5):e0177964. doi: 10.1371/journal.pone.0177964. eCollection 2017.
120 RACK1 promotes tumorigenicity of colon cancer by inducing cell autophagy.Cell Death Dis. 2018 Nov 19;9(12):1148. doi: 10.1038/s41419-018-1113-9.
121 Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells.J Cell Physiol. 2007 Oct;213(1):65-9. doi: 10.1002/jcp.21089.
122 ROBO1 Expression in Metastasizing Breast and Ovarian Cancer: SLIT2-induced Chemotaxis Requires Heparan Sulfates (Heparin).Anticancer Res. 2019 Mar;39(3):1267-1273. doi: 10.21873/anticanres.13237.
123 Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species-independent mitochondrial apoptotic pathway in Smad4 and p53 mutated colon adenocarcinoma HT29 cells.Nutr Res. 2018 Mar;51:67-81. doi: 10.1016/j.nutres.2017.12.011. Epub 2018 Jan 6.
124 Molecular subtypes in stage II-III colon cancer defined by genomic instability: early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A.PLoS One. 2015 Apr 16;10(4):e0122391. doi: 10.1371/journal.pone.0122391. eCollection 2015.
125 Granulocytic Myeloid-Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9.Adv Sci (Weinh). 2019 Jul 22;6(18):1901278. doi: 10.1002/advs.201901278. eCollection 2019 Sep 18.
126 Stability of the N-Terminal Helix and Its Role in Amyloid Formation of Serum Amyloid A.ACS Omega. 2018 Nov 30;3(11):16184-16190. doi: 10.1021/acsomega.8b02377. Epub 2018 Nov 29.
127 Inflammatory hypoxia induces syndecan-2 expression through IL-1-mediated FOXO3a activation in colonic epithelia.FASEB J. 2017 Apr;31(4):1516-1530. doi: 10.1096/fj.201601098R. Epub 2016 Dec 28.
128 Serpin B5 is a CEA-interacting biomarker for colorectal cancer.Int J Cancer. 2014 Apr 1;134(7):1595-604. doi: 10.1002/ijc.28494. Epub 2013 Oct 11.
129 Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.PLoS Genet. 2019 May 6;15(5):e1007687. doi: 10.1371/journal.pgen.1007687. eCollection 2019 May.
130 Role and mechanism of organic cation transporter 3 in oxaliplatin treatment of colon cancer in vitro and in vivo.Oncol Rep. 2019 Oct;42(4):1355-1364. doi: 10.3892/or.2019.7267. Epub 2019 Aug 7.
131 Expression of facilitative glucose transporter 1 mRNA in colon cancer was not regulated by k-ras.Cancer Lett. 2000 Jun 30;154(2):137-42. doi: 10.1016/s0304-3835(00)00354-2.
132 Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer.J Cell Physiol. 2018 Aug;233(8):6067-6076. doi: 10.1002/jcp.26443. Epub 2018 Mar 6.
133 Sphingosine kinase1 promotes the metastasis of colorectal cancer by inducing the epithelialmesenchymal transition mediated by the FAK/AKT/MMPs axis.Int J Oncol. 2019 Jan;54(1):41-52. doi: 10.3892/ijo.2018.4607. Epub 2018 Oct 25.
134 SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-B pathway activation.BMC Cancer. 2019 Jul 12;19(1):685. doi: 10.1186/s12885-019-5904-x.
135 Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.Gastroenterology. 2019 Apr;156(5):1455-1466. doi: 10.1053/j.gastro.2018.11.066. Epub 2018 Dec 6.
136 PHD2 exerts anti-cancer and anti-inflammatory effects in colon cancer xenografts mice via attenuating NF-B activity.Life Sci. 2020 Feb 1;242:117167. doi: 10.1016/j.lfs.2019.117167. Epub 2019 Dec 12.
137 LIGHT Elevation Enhances Immune Eradication of Colon Cancer Metastases.Cancer Res. 2017 Apr 15;77(8):1880-1891. doi: 10.1158/0008-5472.CAN-16-1655. Epub 2017 Mar 1.
138 Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.J Exp Clin Cancer Res. 2016 Mar 31;35:56. doi: 10.1186/s13046-016-0335-x.
139 Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway.Int J Oncol. 2018 Oct;53(4):1481-1492. doi: 10.3892/ijo.2018.4502. Epub 2018 Jul 25.
140 Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer.Cancer Lett. 2018 Jan 1;412:46-58. doi: 10.1016/j.canlet.2017.10.006. Epub 2017 Oct 13.
141 Pharmacological inhibition of USP7 promotes antitumor immunity and contributes to colon cancer therapy.Onco Targets Ther. 2019 Jan 15;12:609-617. doi: 10.2147/OTT.S182806. eCollection 2019.
142 DNA repair protein XPA is differentially expressed in colorectal cancer and predicts better prognosis.Cancer Med. 2018 Jun;7(6):2339-2349. doi: 10.1002/cam4.1480. Epub 2018 Apr 19.
143 Insulin promotes progression of colon cancer by upregulation of ACAT1.Lipids Health Dis. 2018 May 24;17(1):122. doi: 10.1186/s12944-018-0773-x.
144 Predictors of readmission and reoperation in patients with colorectal cancer.Support Care Cancer. 2020 May;28(5):2339-2350. doi: 10.1007/s00520-019-05050-2. Epub 2019 Sep 4.
145 Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.Cancer Res. 1998 Nov 1;58(21):4802-4.
146 Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation.World J Gastroenterol. 2014 Jun 7;20(21):6560-72. doi: 10.3748/wjg.v20.i21.6560.
147 Expression of cellular FLICE-inhibitory protein and its association with p53 mutation in colon cancer.World J Gastroenterol. 2005 Apr 28;11(16):2482-5. doi: 10.3748/wjg.v11.i16.2482.
148 Mirk regulates the exit of colon cancer cells from quiescence.J Biol Chem. 2009 Aug 21;284(34):22916-25. doi: 10.1074/jbc.M109.035519. Epub 2009 Jun 19.
149 Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.Oncol Rep. 2015 Jun;33(6):2681-8. doi: 10.3892/or.2015.3897. Epub 2015 Apr 3.
150 Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer.Cancer Gene Ther. 2014 Oct;21(10):427-33. doi: 10.1038/cgt.2014.46. Epub 2014 Sep 12.
151 In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.J Mol Cell Biol. 2016 Apr;8(2):157-73. doi: 10.1093/jmcb/mjv034. Epub 2015 Jun 1.
152 Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.Ann Surg Oncol. 2016 Mar;23(3):908-17. doi: 10.1245/s10434-015-4967-4. Epub 2015 Nov 17.
153 Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate.Br J Cancer. 2008 Feb 12;98(3):587-95. doi: 10.1038/sj.bjc.6604184. Epub 2008 Jan 22.
154 Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway.PLoS One. 2010 Nov 16;5(11):e14018. doi: 10.1371/journal.pone.0014018.
155 Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.PLoS One. 2016 May 12;11(5):e0155660. doi: 10.1371/journal.pone.0155660. eCollection 2016.
156 ACLY facilitates colon cancer cell metastasis by CTNNB1.J Exp Clin Cancer Res. 2019 Sep 12;38(1):401. doi: 10.1186/s13046-019-1391-9.
157 Downregulation of Activin A Receptor Type 2A Is Associated with Metastatic Potential and Poor Prognosis of Colon Cancer.J Cancer. 2018 Sep 8;9(19):3626-3633. doi: 10.7150/jca.26790. eCollection 2018.
158 Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation.Int J Mol Sci. 2019 May 4;20(9):2198. doi: 10.3390/ijms20092198.
159 ALKBH5 Holds Prognostic Values and Inhibits the Metastasis of Colon Cancer.Pathol Oncol Res. 2020 Jul;26(3):1615-1623. doi: 10.1007/s12253-019-00737-7. Epub 2019 Sep 10.
160 MicroRNA?5/ATXN3 interaction regulates human colon cancer cell growth and migration.Mol Med Rep. 2019 May;19(5):4213-4221. doi: 10.3892/mmr.2019.10090. Epub 2019 Mar 27.
161 Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1.Gastroenterology. 2019 Feb;156(3):662-675.e7. doi: 10.1053/j.gastro.2018.10.030. Epub 2018 Oct 17.
162 Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.Sci Rep. 2017 Nov 24;7(1):16272. doi: 10.1038/s41598-017-16588-8.
163 Bone Morphogenetic Protein 1 Targeting COL1A1 and COL1A2 to Regulate the Epithelial-Mesenchymal Transition Process of Colon Cancer SW620 Cells.J Nanosci Nanotechnol. 2020 Mar 1;20(3):1366-1374. doi: 10.1166/jnn.2020.17362.
164 Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53. Cancer Biol Ther. 2008 Aug;7(8):1305-12. doi: 10.4161/cbt.7.8.6302. Epub 2008 Aug 16.
165 The Prognostic Role of Cancer Stem Cell Markers for Long-term Outcome After Resection of Colonic Liver Metastases.Anticancer Res. 2018 Jan;38(1):313-320. doi: 10.21873/anticanres.12224.
166 Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction.Cancer Lett. 2019 Jun 1;451:79-91. doi: 10.1016/j.canlet.2019.02.050. Epub 2019 Mar 11.
167 Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells.Neoplasia. 2017 Oct;19(10):830-841. doi: 10.1016/j.neo.2017.08.002. Epub 2017 Sep 6.
168 Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis.Oncotarget. 2015 Oct 27;6(33):34389-401. doi: 10.18632/oncotarget.5360.
169 Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.PLoS One. 2019 Oct 17;14(10):e0223574. doi: 10.1371/journal.pone.0223574. eCollection 2019.
170 DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer.Carcinogenesis. 2020 May 14;41(3):303-312. doi: 10.1093/carcin/bgz157.
171 miR-590-3p promotes colon cancer cell proliferation via Wnt/-catenin signaling pathway by inhibiting WIF1 and DKK1.Eur Rev Med Pharmacol Sci. 2017 Nov;21(21):4844-4852.
172 FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer.Nucleic Acids Res. 2019 Feb 28;47(4):1692-1705. doi: 10.1093/nar/gky1230.
173 MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR).Cancer Lett. 2018 May 1;421:145-151. doi: 10.1016/j.canlet.2018.02.026. Epub 2018 Feb 20.
174 Functional Interaction of Hypoxia-Inducible Factor 2-Alpha and Autophagy Mediates Drug Resistance in Colon Cancer Cells.Cancers (Basel). 2019 May 30;11(6):755. doi: 10.3390/cancers11060755.
175 Knockdown of IRE1 suppresses metastatic potential of colon cancer cells through inhibiting FN1-Src/FAK-GTPases signaling.Int J Biochem Cell Biol. 2019 Sep;114:105572. doi: 10.1016/j.biocel.2019.105572. Epub 2019 Jul 18.
176 KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.Clin Epigenetics. 2018 Apr 4;10:44. doi: 10.1186/s13148-018-0473-4. eCollection 2018.
177 The concentrations of EGFR, LRG1, ITIH4, and F5 in serum correlate with the number of colonic adenomas in ApcPirc/+ rats.Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9. doi: 10.1158/1940-6207.CAPR-14-0056. Epub 2014 Sep 8.
178 Identification of Cross Talk between FoxM1 and RASSF1A as a Therapeutic Target of Colon Cancer.Cancers (Basel). 2019 Feb 8;11(2):199. doi: 10.3390/cancers11020199.
179 The role of lymph node size and FOXP3+ regulatory T cells in node-negative colon cancer.J Clin Pathol. 2017 May;70(5):443-447. doi: 10.1136/jclinpath-2016-203978. Epub 2016 Nov 22.
180 MicroRNA (miR)-597-5p Inhibits Colon Cancer Cell Migration and Invasion by Targeting FOS-Like Antigen 2 (FOSL2).Front Oncol. 2019 Jun 12;9:495. doi: 10.3389/fonc.2019.00495. eCollection 2019.
181 Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15.Aging Cell. 2019 Dec;18(6):e13013. doi: 10.1111/acel.13013. Epub 2019 Aug 6.
182 HDAC inhibitors show differential epigenetic regulation and cell survival strategies on p53 mutant colon cancer cells.J Biomol Struct Dyn. 2018 Mar;36(4):938-955. doi: 10.1080/07391102.2017.1302820. Epub 2017 Mar 28.
183 AKT2 phosphorylation of hexokinase 2 at T473 promotes tumorigenesis and metastasis in colon cancer cells via NF-B, HIF1, MMP2, and MMP9 upregulation.Cell Signal. 2019 Jun;58:99-110. doi: 10.1016/j.cellsig.2019.03.011. Epub 2019 Mar 12.
184 H19 promotes the migration and invasion of colon cancer by sponging miR-138 to upregulate the expression of HMGA1.Int J Oncol. 2017 May;50(5):1801-1809. doi: 10.3892/ijo.2017.3941. Epub 2017 Mar 29.
185 Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway.Mol Cancer Ther. 2020 Jan;19(1):135-146. doi: 10.1158/1535-7163.MCT-19-0413. Epub 2019 Sep 25.
186 HMGCS2 enhances invasion and metastasis via direct interaction with PPAR to activate Src signaling in colorectal cancer and oral cancer.Oncotarget. 2017 Apr 4;8(14):22460-22476. doi: 10.18632/oncotarget.13006.
187 AQP5 silencing suppresses p38 MAPK signaling and improves drug resistance in colon cancer cells.Tumour Biol. 2014 Jul;35(7):7035-45. doi: 10.1007/s13277-014-1956-3. Epub 2014 Apr 23.
188 BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.Mol Carcinog. 2018 Feb;57(2):284-294. doi: 10.1002/mc.22755. Epub 2017 Nov 14.
189 MiR-214 sensitizes human colon cancer cells to 5-FU by targeting Hsp27.Cell Mol Biol Lett. 2019 Mar 14;24:22. doi: 10.1186/s11658-019-0143-3. eCollection 2019.
190 Cancer therapy with major histocompatibility complex-deficient and interferon -producing myeloid cells derived from allogeneic embryonic stem cells.Cancer Sci. 2019 Oct;110(10):3027-3037. doi: 10.1111/cas.14144. Epub 2019 Aug 7.
191 Cell-Based IL-15:IL-15R Secreting Vaccine as an Effective Therapy for CT26 Colon Cancer in Mice.Mol Cells. 2019 Dec 31;42(12):869-883. doi: 10.14348/molcells.2019.0188.
192 Integrated bioinformatics analysis of key genes involved in progress of colon cancer.Mol Genet Genomic Med. 2019 Apr;7(4):e00588. doi: 10.1002/mgg3.588. Epub 2019 Feb 11.
193 A Transcriptomic Insight into the Impact of Colon Cancer Cells on Mast Cells.Int J Mol Sci. 2019 Apr 4;20(7):1689. doi: 10.3390/ijms20071689.
194 Has_circ_0055625 from circRNA profile increases colon cancer cell growth by sponging miR-106b-5p.J Cell Biochem. 2019 Mar;120(3):3027-3037. doi: 10.1002/jcb.27355. Epub 2018 Dec 5.
195 MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells.Oncogene. 2018 Feb 22;37(8):1031-1040. doi: 10.1038/onc.2017.396. Epub 2017 Oct 30.
196 Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.BMC Genomics. 2006 Jun 13;7:148. doi: 10.1186/1471-2164-7-148.
197 L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.Sci Rep. 2017 Nov 3;7(1):14979. doi: 10.1038/s41598-017-15135-9.
198 Cloning, expression of the truncation of recombinant peroxidase derived from millet bran and its reversal effects on 5-Fu resistance in colorectal cancer.Int J Biol Macromol. 2019 Jul 1;132:871-879. doi: 10.1016/j.ijbiomac.2019.03.111. Epub 2019 Mar 19.
199 miRNA-766 induces apoptosis of human colon cancer cells through the p53/Bax signaling pathway by MDM4.Exp Ther Med. 2019 May;17(5):4100-4108. doi: 10.3892/etm.2019.7436. Epub 2019 Mar 26.
200 Design, synthesis and biological evaluation of pyridone-aminal derivatives as MNK1/2 inhibitors.Bioorg Med Chem. 2019 Apr 1;27(7):1211-1225. doi: 10.1016/j.bmc.2019.02.007. Epub 2019 Feb 2.
201 MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells.Oncol Rep. 2019 Nov;42(5):1915-1923. doi: 10.3892/or.2019.7292. Epub 2019 Aug 23.
202 Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein.Naunyn Schmiedebergs Arch Pharmacol. 2016 Nov;389(11):1171-1182. doi: 10.1007/s00210-016-1268-9. Epub 2016 Jul 22.
203 Construing the Biochemical and Molecular Mechanism Underlying the In Vivo and In Vitro Chemotherapeutic Efficacy of Ruthenium-Baicalein Complex in Colon Cancer.Int J Biol Sci. 2019 Apr 22;15(5):1052-1071. doi: 10.7150/ijbs.31143. eCollection 2019.
204 Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.Int J Oncol. 2016 Aug;49(2):639-45. doi: 10.3892/ijo.2016.3550. Epub 2016 Jun 1.
205 The nuclear orphan receptor NR4A1 regulates 1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.Mol Carcinog. 2017 Sep;56(9):2066-2075. doi: 10.1002/mc.22662. Epub 2017 May 9.
206 Methylation of OSMR gene is frequently observed in non-invasive colorectal cancer.Anticancer Res. 2011 Apr;31(4):1293-5.
207 Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis.Cancer Sci. 2007 Mar;98(3):321-8. doi: 10.1111/j.1349-7006.2007.00390.x.
208 Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice.Cancer Res. 2013 May 1;73(9):2806-16. doi: 10.1158/0008-5472.CAN-12-2374. Epub 2013 Jan 29.
209 Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment.Oncogene. 2019 Feb;38(8):1309-1323. doi: 10.1038/s41388-018-0527-2. Epub 2018 Oct 10.
210 Shikonin-induced Apoptosis of Colon Cancer Cells Is Reduced by Peroxiredoxin V Expression.Anticancer Res. 2019 Nov;39(11):6115-6123. doi: 10.21873/anticanres.13819.
211 Modulating PKC Activity to Target Wnt/-Catenin Signaling in Colon Cancer.Cancers (Basel). 2019 May 18;11(5):693. doi: 10.3390/cancers11050693.
212 Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival.Oncotarget. 2016 Apr 12;7(15):20919-33. doi: 10.18632/oncotarget.8062.
213 Role and mechanism of circ-PRKCI in hepatocellular carcinoma.World J Gastroenterol. 2019 Apr 28;25(16):1964-1974. doi: 10.3748/wjg.v25.i16.1964.
214 PKC Phosphorylates SIRT6 to Mediate Fatty Acid -Oxidation in Colon Cancer Cells.Neoplasia. 2019 Jan;21(1):61-73. doi: 10.1016/j.neo.2018.11.008. Epub 2018 Nov 30.
215 Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer.Oncol Rep. 2019 Mar;41(3):1691-1699. doi: 10.3892/or.2018.6938. Epub 2018 Dec 18.
216 PTBP1 knockdown overcomes the resistance to vincristine and oxaliplatin in drug-resistant colon cancer cells through regulation of glycolysis.Biomed Pharmacother. 2018 Dec;108:194-200. doi: 10.1016/j.biopha.2018.09.031. Epub 2018 Sep 13.
217 DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. J Cancer Res Clin Oncol. 2009 Dec;135(12):1791-8. doi: 10.1007/s00432-009-0627-z. Epub 2009 Jun 24.
218 Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition.Onco Targets Ther. 2019 Jul 16;12:5713-5728. doi: 10.2147/OTT.S208738. eCollection 2019.
219 The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.Sci Rep. 2019 Dec 6;9(1):18557. doi: 10.1038/s41598-019-54931-3.
220 Ribosomal Protein L15 is involved in Colon Carcinogenesis.Int J Med Sci. 2019 Aug 6;16(8):1132-1141. doi: 10.7150/ijms.34386. eCollection 2019.
221 3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.Cancer Lett. 2019 Apr 28;448:20-30. doi: 10.1016/j.canlet.2019.01.031. Epub 2019 Feb 1.
222 Overexpression of Chimeric RNA by Retroviral Transduction.Methods Mol Biol. 2020;2079:155-166. doi: 10.1007/978-1-4939-9904-0_12.
223 Reversible regulation of SATB1 ubiquitination by USP47 and SMURF2 mediates colon cancer cell proliferation and tumor progression.Cancer Lett. 2019 Apr 28;448:40-51. doi: 10.1016/j.canlet.2019.01.039. Epub 2019 Feb 8.
224 Discovery of common and rare genetic risk variants for colorectal cancer.Nat Genet. 2019 Jan;51(1):76-87. doi: 10.1038/s41588-018-0286-6. Epub 2018 Dec 3.
225 Novel Common Genetic Susceptibility Loci for Colorectal Cancer.J Natl Cancer Inst. 2019 Feb 1;111(2):146-157. doi: 10.1093/jnci/djy099.
226 Serum extracellular vesicles contain SPARC and LRG1 as biomarkers of colon cancer and differ by tumour primary location.EBioMedicine. 2019 Dec;50:211-223. doi: 10.1016/j.ebiom.2019.11.003. Epub 2019 Nov 18.
227 Deficiency in STAT1 Signaling Predisposes Gut Inflammation and Prompts Colorectal Cancer Development.Cancers (Basel). 2018 Sep 19;10(9):341. doi: 10.3390/cancers10090341.
228 SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion.Cancer Immunol Res. 2019 Mar;7(3):414-427. doi: 10.1158/2326-6066.CIR-18-0126. Epub 2019 Jan 4.
229 Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer.Biochem Biophys Res Commun. 2018 Dec 2;506(4):901-906. doi: 10.1016/j.bbrc.2018.10.137. Epub 2018 Nov 2.
230 TGF-2, catalase activity, H(2)O(2) output and metastatic potential of diverse types of tumour.Free Radic Biol Med. 2019 Apr;134:282-287. doi: 10.1016/j.freeradbiomed.2019.01.010. Epub 2019 Jan 9.
231 Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway.Carcinogenesis. 2014 Feb;35(2):324-32. doi: 10.1093/carcin/bgt332. Epub 2013 Oct 1.
232 Overexpression of TrpC5 promotes tumor metastasis via the HIF-1-Twist signaling pathway in colon cancer.Clin Sci (Lond). 2017 Sep 22;131(19):2439-2450. doi: 10.1042/CS20171069. Print 2017 Oct 1.
233 Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.Cell Commun Signal. 2017 Aug 15;15(1):30. doi: 10.1186/s12964-017-0187-9.
234 Microarraybased analysis of COL11A1 and TWIST1 as important differentiallyexpressed pathogenic genes between left and rightsided colon cancer.Mol Med Rep. 2019 Nov;20(5):4202-4214. doi: 10.3892/mmr.2019.10667. Epub 2019 Sep 10.
235 Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer.BMC Cancer. 2008 Jul 25;8:210. doi: 10.1186/1471-2407-8-210.
236 Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress.Cell Death Dis. 2019 Feb 20;10(3):170. doi: 10.1038/s41419-018-1271-9.
237 XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.Oncogene. 2019 Feb;38(9):1448-1460. doi: 10.1038/s41388-018-0513-8. Epub 2018 Oct 1.
238 Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes.Anticancer Res. 2018 Jan;38(1):131-136. doi: 10.21873/anticanres.12200.
239 Novel association between heterozygous genotype of single nucleotide polymorphism C218T in drug transporter ABCC1 gene and increased risk of colon cancer.Saudi Med J. 2019 Mar;40(3):224-229. doi: 10.15537/smj.2019.3.23650.
240 Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer.Cancer Lett. 2019 Feb 1;442:104-112. doi: 10.1016/j.canlet.2018.10.032. Epub 2018 Oct 28.
241 G protein-coupled receptor LGR6 is an independent risk factor for colon adenocarcinoma.Front Med. 2019 Aug;13(4):482-491. doi: 10.1007/s11684-018-0633-0. Epub 2018 Jul 4.
242 Recent studies on the identification of proliferative abnormalities and of oncogenic potential of cutaneous cells in individuals at increased risk of colon cancer.Semin Oncol. 1976 Dec;3(4):369-72.
243 TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.Mol Cell Biochem. 2017 Jan;425(1-2):191-202. doi: 10.1007/s11010-016-2873-0. Epub 2016 Nov 12.
244 miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer.Oncol Rep. 2017 Jan;37(1):123-130. doi: 10.3892/or.2016.5259. Epub 2016 Nov 18.
245 Differential coupling of the PAC1 SV1 splice variant on human colonic tumors to the activation of intracellular cAMP but not intracellular Ca2+ does not activate tumor proliferation.J Mol Neurosci. 2004;22(1-2):83-92. doi: 10.1385/JMN:22:1-2:83.
246 Adiponectin and colon cancer: evidence for inhibitory effects on viability and migration of human colorectal cell lines.Mol Cell Biochem. 2018 Nov;448(1-2):125-135. doi: 10.1007/s11010-018-3319-7. Epub 2018 Feb 14.
247 Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer.Sci Rep. 2017 Dec 13;7(1):17488. doi: 10.1038/s41598-017-17573-x.
248 AGR2 is a target of canonical Wnt/-catenin signaling and is important for stemness maintenance in colorectal cancer stem cells.Biochem Biophys Res Commun. 2019 Aug 6;515(4):600-606. doi: 10.1016/j.bbrc.2019.05.154. Epub 2019 Jun 6.
249 Digital transcript profile analysis with aRNA-LongSAGE validates FERMT1 as a potential novel prognostic marker for colon cancer.Clin Cancer Res. 2011 May 1;17(9):2908-18. doi: 10.1158/1078-0432.CCR-10-2552. Epub 2011 Jan 10.
250 Plasma fetuin-A concentration, genetic variation in the AHSG gene and risk of colorectal cancer.Int J Cancer. 2015 Aug 15;137(4):911-20. doi: 10.1002/ijc.29448. Epub 2015 Feb 5.
251 In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells.Cancer Med. 2019 Sep;8(12):5662-5672. doi: 10.1002/cam4.2409. Epub 2019 Jul 31.
252 Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers. Chem Biol Interact. 2013 Feb 25;202(1-3):234-42.
253 SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells.Gastroenterology. 2011 Jul;141(1):279-91, 291.e1-5. doi: 10.1053/j.gastro.2011.04.008. Epub 2011 Apr 16.
254 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.FASEB J. 2015 Jun;29(6):2359-70. doi: 10.1096/fj.14-264515. Epub 2015 Feb 24.
255 Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor.Vascul Pharmacol. 2017 Feb;89:19-30. doi: 10.1016/j.vph.2016.10.004. Epub 2016 Oct 4.
256 Expression of angiogenic growth factors VEGF, bFGF and ANG1 in colon cancer after bevacizumab treatment in vitro: A potential self-regulating mechanism.Oncol Rep. 2017 Jan;37(1):601-607. doi: 10.3892/or.2016.5231. Epub 2016 Nov 8.
257 Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines.Oncol Rep. 2012 May;27(5):1541-7. doi: 10.3892/or.2012.1672. Epub 2012 Feb 3.
258 Fusobacterium nucleatum prevents apoptosis in colorectal cancer cells via the ANO1 pathway.Cancer Manag Res. 2019 Oct 29;11:9057-9066. doi: 10.2147/CMAR.S185766. eCollection 2019.
259 Antitumour effect of glucooligosaccharides obtained via hydrolysis of -(1?)-glucan from Fomitopsis betulina.Mol Biol Rep. 2019 Dec;46(6):5977-5982. doi: 10.1007/s11033-019-05032-x. Epub 2019 Aug 22.
260 Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.PLoS One. 2013 Jul 1;8(7):e68072. doi: 10.1371/journal.pone.0068072. Print 2013.
261 Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population.J Appl Genet. 2010;51(3):343-52. doi: 10.1007/BF03208865.
262 Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819849068. doi: 10.1177/1533033819849068.
263 Upregulation of ASAP3 contributes to colorectal carcinogenesis and indicates poor survival outcome.Cancer Sci. 2017 Aug;108(8):1544-1555. doi: 10.1111/cas.13281. Epub 2017 Jun 14.
264 Prognostic value of humbug gene overexpression in stage II colon cancer.Hum Pathol. 2007 Jan;38(1):17-25. doi: 10.1016/j.humpath.2006.07.009. Epub 2006 Oct 3.
265 The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.J Biol Chem. 2014 Sep 5;289(36):25306-16. doi: 10.1074/jbc.M114.557546. Epub 2014 Jul 18.
266 Genetic disruption of tubulin acetyltransferase, TAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/-catenin signaling.Biochem Biophys Res Commun. 2017 Jan 1;482(1):8-14. doi: 10.1016/j.bbrc.2016.11.039. Epub 2016 Nov 9.
267 Activating transcription factor 3 promotes colon cancer metastasis.Tumour Biol. 2014 Aug;35(8):8329-34. doi: 10.1007/s13277-014-2044-4. Epub 2014 May 24.
268 Alterations in the ATP2A2 gene in correlation with colon and lung cancer.Cancer Genet Cytogenet. 2006 Dec;171(2):105-11. doi: 10.1016/j.cancergencyto.2006.06.016.
269 A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.Cancer. 2018 Mar 1;124(5):1070-1082. doi: 10.1002/cncr.31136. Epub 2017 Nov 30.
270 Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon cancer development.Am J Pathol. 2010 Dec;177(6):2816-26. doi: 10.2353/ajpath.2010.100047. Epub 2010 Nov 5.
271 Zinc--2-glycoprotein: a candidate biomarker for colon cancer diagnosis in Chinese population.Int J Mol Sci. 2014 Dec 30;16(1):691-703. doi: 10.3390/ijms16010691.
272 Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial.Br J Cancer. 2012 Mar 13;106(6):1239-45. doi: 10.1038/bjc.2012.53. Epub 2012 Feb 21.
273 Identification of a novel aspartic-like protease differentially expressed in human breast cancer cell lines.Biochim Biophys Acta. 2000 Jun 15;1501(2-3):125-37. doi: 10.1016/s0925-4439(00)00014-4.
274 BACH1 silencing by siRNA inhibits migration of HT-29 colon cancer cells through reduction of metastasis-related genes.Biomed Pharmacother. 2016 Dec;84:191-198. doi: 10.1016/j.biopha.2016.09.021. Epub 2016 Sep 19.
275 Malignant transformation of normal enterocytes following downregulation of Bak expression.Digestion. 2008;77(1):48-56. doi: 10.1159/000121411. Epub 2008 Mar 18.
276 BAP1 expression is prognostic in breast and uveal melanoma but not colon cancer and is highly positively correlated with RBM15B and USP19.PLoS One. 2019 Feb 4;14(2):e0211507. doi: 10.1371/journal.pone.0211507. eCollection 2019.
277 Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3/NF-B signaling pathway.Cancer Gene Ther. 2020 May;27(5):368-377. doi: 10.1038/s41417-019-0098-6. Epub 2019 Jun 11.
278 Targeted delivery of phycocyanin for the prevention of colon cancer using electrospun fibers.Food Funct. 2019 Apr 17;10(4):1816-1825. doi: 10.1039/c8fo02447b.
279 Expression of a novel Bcl-2 related gene, Bfl-1, in various human cancers and cancer cell lines.Anticancer Res. 1997 Nov-Dec;17(6D):4619-22.
280 MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA.J Cell Physiol. 2015 Mar;230(3):535-45. doi: 10.1002/jcp.24366.
281 Effects of Beclin 1 overexpression on aggressive phenotypes of colon cancer cells.Oncol Lett. 2019 Feb;17(2):2441-2450. doi: 10.3892/ol.2018.9817. Epub 2018 Dec 10.
282 gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Res. 2009 Jan 15;69(2):573-82. doi: 10.1158/0008-5472.CAN-08-2088.
283 Effect of RNAi-mediated silencing of Livin gene on biological properties of colon cancer cell line LoVo.Genet Mol Res. 2014 May 16;13(2):3832-41. doi: 10.4238/2014.May.16.8.
284 Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of -catenin in colon cancer stem cells.Mol Carcinog. 2018 May;57(5):664-677. doi: 10.1002/mc.22791. Epub 2018 Mar 14.
285 Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling.Int J Oncol. 2018 Nov;53(5):2091-2101. doi: 10.3892/ijo.2018.4527. Epub 2018 Aug 16.
286 A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival.J Natl Cancer Inst. 2015 Jun 13;107(9):djv160. doi: 10.1093/jnci/djv160. Print 2015 Sep.
287 BRCA2 Deletion Induces Alternative Lengthening of Telomeres in Telomerase Positive Colon Cancer Cells.Genes (Basel). 2019 Sep 10;10(9):697. doi: 10.3390/genes10090697.
288 miR-27a-3p regulates proliferation and apoptosis of colon cancer cells by potentially targeting BTG1.Oncol Lett. 2019 Sep;18(3):2825-2834. doi: 10.3892/ol.2019.10629. Epub 2019 Jul 18.
289 BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.J Pathol. 2020 Feb;250(2):134-147. doi: 10.1002/path.5347. Epub 2019 Dec 2.
290 C1QBP is upregulated in colon cancer and binds to apolipoprotein A-I.Exp Ther Med. 2017 May;13(5):2493-2500. doi: 10.3892/etm.2017.4249. Epub 2017 Mar 21.
291 Complement 5a stimulates macrophage polarization and contributes to tumor metastases of colon cancer.Exp Cell Res. 2018 May 15;366(2):127-138. doi: 10.1016/j.yexcr.2018.03.009. Epub 2018 Mar 15.
292 Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice.Gut. 2015 Dec;64(12):1905-12. doi: 10.1136/gutjnl-2014-307663. Epub 2014 Nov 26.
293 Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP-WT1-TBL1 axis.Gut. 2016 Sep;65(9):1482-93. doi: 10.1136/gutjnl-2014-308614. Epub 2015 Jun 12.
294 Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.Carcinogenesis. 2004 Aug;25(8):1495-505. doi: 10.1093/carcin/bgh155. Epub 2004 Apr 1.
295 Small RNA sequencing of sessile serrated polyps identifies microRNA profile associated with colon cancer.Genes Chromosomes Cancer. 2019 Jan;58(1):23-33. doi: 10.1002/gcc.22686. Epub 2018 Nov 18.
296 Suppressive effect of an analog of the antimicrobial peptide of LL?7 on colon cancer cells via exosomeencapsulated miRNAs.Int J Mol Med. 2018 Dec;42(6):3009-3016. doi: 10.3892/ijmm.2018.3875. Epub 2018 Sep 13.
297 Mutational analysis of CASP10 gene in colon, breast, lung and hepatocellular carcinomas.Pathology. 2010 Jan;42(1):73-6. doi: 10.3109/00313020903434371.
298 microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.Mol Cancer. 2014 May 26;13:124. doi: 10.1186/1476-4598-13-124.
299 Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population.Br J Cancer. 2017 Sep 5;117(6):898-906. doi: 10.1038/bjc.2017.242. Epub 2017 Aug 1.
300 miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer.Sci Rep. 2019 Apr 1;9(1):5405. doi: 10.1038/s41598-019-41862-2.
301 Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation.Biochem Pharmacol. 2018 Mar;149:186-204. doi: 10.1016/j.bcp.2017.10.011. Epub 2017 Oct 23.
302 The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.Eur J Cancer. 2010 Aug;46(12):2304-13. doi: 10.1016/j.ejca.2010.05.011. Epub 2010 Jun 9.
303 Curcumin Reverses 5-Fluorouracil Resistance by Promoting Human Colon Cancer HCT-8/5-FU Cell Apoptosis and Down-regulating Heat Shock Protein 27 and P-Glycoprotein.Chin J Integr Med. 2019 Jun;25(6):416-424. doi: 10.1007/s11655-018-2997-z. Epub 2018 Nov 27.
304 Dual-agonist occupancy of orexin receptor 1 and cholecystokinin A receptor heterodimers decreases G-protein-dependent signaling and migration in the human colon cancer cell line HT-29.Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1153-1164. doi: 10.1016/j.bbamcr.2017.03.003. Epub 2017 Mar 10.
305 MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA.Oncotarget. 2017 Feb 28;8(9):14887-14896. doi: 10.18632/oncotarget.14841.
306 The CCL21/CCR7 pathway plays a key role in human colon cancer metastasis through regulation of matrix metalloproteinase-9.Dig Liver Dis. 2011 Jan;43(1):40-7. doi: 10.1016/j.dld.2010.05.013. Epub 2010 Jul 6.
307 Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1 and VEGF.Mol Carcinog. 2011 Sep;50(9):707-18. doi: 10.1002/mc.20736. Epub 2011 Jan 25.
308 NPTX1 inhibits colon cancer cell proliferation through down-regulating cyclin A2 and CDK2 expression.Cell Biol Int. 2018 May;42(5):589-597. doi: 10.1002/cbin.10935. Epub 2018 Feb 6.
309 Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo.Cell Biol Int. 2012 Aug 1;36(8):765-70. doi: 10.1042/CBI20110404.
310 Adiponectin and metformin additively attenuate IL1-induced malignant potential of colon cancer.Endocr Relat Cancer. 2013 Oct 24;20(6):849-59. doi: 10.1530/ERC-13-0240. Print 2013 Dec.
311 CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis.Clin Exp Metastasis. 2014 Dec;31(8):977-89. doi: 10.1007/s10585-014-9684-z. Epub 2014 Oct 18.
312 Overexpression of Evi-1 oncoprotein represses TGF- signaling in colorectal cancer.Mol Carcinog. 2013 Apr;52(4):255-264. doi: 10.1002/mc.21852. Epub 2011 Dec 7.
313 Modified TLR-mediated downregulation of miR-125b-5p enhances CD248 (endosialin)-induced metastasis and drug resistance in colorectal cancer cells.Mol Carcinog. 2020 Feb;59(2):154-167. doi: 10.1002/mc.23137. Epub 2019 Nov 19.
314 RETRACTED: KYA1797K down-regulates PD-L1 in colon cancer stem cells to block immune evasion by suppressing the -catenin/STT3 signaling pathway.Int Immunopharmacol. 2020 Jan;78:106003. doi: 10.1016/j.intimp.2019.106003. Epub 2019 Dec 5.
315 Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells.J Exp Clin Cancer Res. 2019 May 9;38(1):190. doi: 10.1186/s13046-019-1205-0.
316 CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells.BMC Cancer. 2014 Oct 9;14:754. doi: 10.1186/1471-2407-14-754.
317 microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.Cancer Res. 2009 Oct 15;69(20):8157-65. doi: 10.1158/0008-5472.CAN-09-1996. Epub 2009 Oct 13.
318 Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.Oncotarget. 2016 Aug 2;7(31):49597-49610. doi: 10.18632/oncotarget.10414.
319 Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion.J Proteome Res. 2018 Jan 5;17(1):265-275. doi: 10.1021/acs.jproteome.7b00550. Epub 2017 Nov 7.
320 Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.Clin Cancer Res. 2013 Nov 1;19(21):6006-19. doi: 10.1158/1078-0432.CCR-13-1130. Epub 2013 Sep 11.
321 Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.Mol Oncol. 2018 Mar;12(3):287-304. doi: 10.1002/1878-0261.12148. Epub 2018 Jan 28.
322 Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors.Bioorg Med Chem Lett. 2017 Sep 15;27(18):4399-4404. doi: 10.1016/j.bmcl.2017.08.018. Epub 2017 Aug 12.
323 NEAT1 promotes colon cancer progression through sponging miR-495-3p and activating CDK6 in vitro and in vivo.J Cell Physiol. 2019 Nov;234(11):19582-19591. doi: 10.1002/jcp.28557. Epub 2019 Jun 7.
324 Cyclin-dependent kinase 9 expression and its association with CD8(+) T cell infiltration in microsatellite-stable colorectal cancer.Oncol Lett. 2019 Dec;18(6):6046-6056. doi: 10.3892/ol.2019.10970. Epub 2019 Oct 8.
325 Inhibition of cancer growth and induction of apoptosis by BGP-13 and BGP-15, new calcipotriene-derived vitamin D3 analogs, in-vitro and in-vivo studies.Invest New Drugs. 2013 Apr;31(2):247-55. doi: 10.1007/s10637-012-9839-1. Epub 2012 Jun 2.
326 Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G591-7. doi: 10.1152/ajpgi.00055.2008. Epub 2008 Jul 24.
327 Combined 5-FU and ChoK inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts.PLoS One. 2013 Jun 10;8(6):e64961. doi: 10.1371/journal.pone.0064961. Print 2013.
328 REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival.Cell Death Dis. 2017 Jan 5;8(1):e2536. doi: 10.1038/cddis.2016.462.
329 The Role of M3 Muscarinic Receptor Ligand-Induced Kinase Signaling in Colon Cancer Progression.Cancers (Basel). 2019 Mar 5;11(3):308. doi: 10.3390/cancers11030308.
330 Up-regulation of CIT promotes the growth of colon cancer cells.Oncotarget. 2017 Jun 27;8(42):71954-71964. doi: 10.18632/oncotarget.18615. eCollection 2017 Sep 22.
331 Prognostic value of chloride channel accessory mRNA expression in colon cancer.Oncol Lett. 2019 Sep;18(3):2967-2976. doi: 10.3892/ol.2019.10615. Epub 2019 Jul 15.
332 CLIC1 overexpression is associated with poor prognosis in gallbladder cancer.Tumour Biol. 2015 Jan;36(1):193-8. doi: 10.1007/s13277-014-2606-5. Epub 2014 Sep 17.
333 The CLN3 gene is a novel molecular target for cancer drug discovery.Cancer Res. 2002 Feb 1;62(3):801-8.
334 Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression.Oncogene. 2017 Feb 23;36(8):1069-1079. doi: 10.1038/onc.2016.271. Epub 2016 Aug 15.
335 Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue.PLoS One. 2013 Sep 6;8(9):e73866. doi: 10.1371/journal.pone.0073866. eCollection 2013.
336 Integrated analysis of gene expression signatures associated with colon cancer from three datasets.Gene. 2018 May 15;654:95-102. doi: 10.1016/j.gene.2018.02.007. Epub 2018 Feb 3.
337 Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis.Mol Cell Biol. 2009 Oct;29(19):5277-89. doi: 10.1128/MCB.00001-09. Epub 2009 Jul 20.
338 Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer.BMC Cancer. 2013 Jun 5;13:277. doi: 10.1186/1471-2407-13-277.
339 MiR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting subunit of protein kinase CKII in human colorectal cancer cells.Biochem Biophys Res Commun. 2012 Dec 14;429(3-4):173-9. doi: 10.1016/j.bbrc.2012.10.117. Epub 2012 Nov 5.
340 Investigation of fusion gene expression in HCT116 cells.Oncol Lett. 2017 Dec;14(6):6962-6968. doi: 10.3892/ol.2017.7055. Epub 2017 Sep 25.
341 Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair.Clin Chem. 2017 Mar;63(3):700-713. doi: 10.1373/clinchem.2016.263582. Epub 2016 Dec 22.
342 High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.Ann Surg Oncol. 2015 Jul;22(7):2431-8. doi: 10.1245/s10434-014-4155-y. Epub 2014 Oct 28.
343 A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.Sci Rep. 2015 May 20;5:10442. doi: 10.1038/srep10442.
344 Fibroblast-derived CXCL12 regulates PTEN expression and is associated with the proliferation and invasion of colon cancer cells via PI3k/Akt signaling.Cell Commun Signal. 2019 Sep 10;17(1):119. doi: 10.1186/s12964-019-0432-5.
345 CXCL13-CXCR5 axis promotes the growth and invasion of colon cancer cells via PI3K/AKT pathway.Mol Cell Biochem. 2015 Feb;400(1-2):287-95. doi: 10.1007/s11010-014-2285-y. Epub 2014 Dec 5.
346 Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival.Cancer Sci. 2015 Mar;106(3):262-9. doi: 10.1111/cas.12603. Epub 2015 Mar 5.
347 CXCR4/TGF-1 mediated hepatic stellate cells differentiation into carcinoma-associated fibroblasts and promoted liver metastasis of colon cancer.Cancer Biol Ther. 2020;21(3):258-268. doi: 10.1080/15384047.2019.1685157. Epub 2019 Dec 11.
348 Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.Gastroenterology. 2016 Jun;150(7):1633-1645. doi: 10.1053/j.gastro.2016.02.076. Epub 2016 Mar 8.
349 Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.Mutat Res. 2002 Sep 30;506-507:175-85. doi: 10.1016/s0027-5107(02)00164-1.
350 Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats.Environ Toxicol. 2019 May;34(5):610-625. doi: 10.1002/tox.22727. Epub 2019 Feb 5.
351 Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer.Oncotarget. 2017 May 23;8(21):34773-34786. doi: 10.18632/oncotarget.16718.
352 A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells.Oncotarget. 2017 May 23;8(21):35033-35047. doi: 10.18632/oncotarget.16591.
353 Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients.J Exp Clin Cancer Res. 2012 Sep 11;31(1):71. doi: 10.1186/1756-9966-31-71.
354 Fascin1 suppresses RIG-I-like receptor signaling and interferon- production by associating with IB kinase (IKK) in colon cancer.J Biol Chem. 2018 Apr 27;293(17):6326-6336. doi: 10.1074/jbc.M117.819201. Epub 2018 Mar 1.
355 Expression and new exon mutations of the human Beta defensins and their association on colon cancer development.PLoS One. 2015 Jun 3;10(6):e0126868. doi: 10.1371/journal.pone.0126868. eCollection 2015.
356 DEK Expression is controlled by E2F and deregulated in diverse tumor types.Cell Cycle. 2006 Jun;5(11):1202-7. doi: 10.4161/cc.5.11.2801. Epub 2006 Jun 1.
357 Early prediction of tumor response to bevacizumab treatment in murine colon cancer models using three-dimensional dynamic contrast-enhanced ultrasound imaging.Angiogenesis. 2017 Nov;20(4):547-555. doi: 10.1007/s10456-017-9566-5. Epub 2017 Jul 18.
358 Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.J Biomol Struct Dyn. 2017 May;35(7):1474-1490. doi: 10.1080/07391102.2016.1186560. Epub 2016 Aug 5.
359 An apoptosis-independent role of SMAC in tumor suppression.Oncogene. 2013 May 9;32(19):2380-9. doi: 10.1038/onc.2012.265. Epub 2012 Jul 2.
360 Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines.Int J Cancer. 1999 Mar 15;80(6):919-29. doi: 10.1002/(sici)1097-0215(19990315)80:6<919::aid-ijc19>3.0.co;2-u.
361 Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.Cancer Res. 2011 Mar 1;71(5):1520-5. doi: 10.1158/0008-5472.CAN-10-2817. Epub 2010 Dec 30.
362 Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells.Oncotarget. 2019 Feb 8;10(12):1238-1249. doi: 10.18632/oncotarget.26664. eCollection 2019 Feb 8.
363 Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26.BMC Cancer. 2015 Nov 10;15:882. doi: 10.1186/s12885-015-1702-2.
364 Thymidilate synthase expression predicts longer survival in patients with stage II colon cancer treated with 5-flurouracil independently of microsatellite instability.J Cancer Res Clin Oncol. 2011 Feb;137(2):201-10. doi: 10.1007/s00432-010-0872-1. Epub 2010 Apr 13.
365 Prognostic significance of miR-215 in colon cancer.Clin Colorectal Cancer. 2011 Dec;10(4):340-7. doi: 10.1016/j.clcc.2011.06.002. Epub 2011 Jul 12.
366 Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas.Oncol Rep. 2012 Sep;28(3):931-6. doi: 10.3892/or.2012.1862. Epub 2012 Jun 12.
367 E2F1 facilitates DNA break repair by localizing to break sites and enhancing the expression of homologous recombination factors.Exp Mol Med. 2019 Sep 18;51(9):1-12. doi: 10.1038/s12276-019-0307-2.
368 Systemic delivery of full-length C/EBP beta/liposome complex suppresses growth of human colon cancer in nude mice.Cell Res. 2005 Oct;15(10):770-6. doi: 10.1038/sj.cr.7290346.
369 Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.Int J Cancer. 2013 Mar 1;132(5):1004-12. doi: 10.1002/ijc.27762. Epub 2012 Aug 24.
370 Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells.Autophagy. 2014 Sep;10(9):1495-508. doi: 10.4161/auto.29164. Epub 2014 Jun 19.
371 Bufalin-Loaded CaP/DPPE-PEG-EGF Nanospheres: Preparation, Cellular Uptake, Distribution, and Anti-Tumor Effects.J Biomed Nanotechnol. 2019 Feb 1;15(2):329-339. doi: 10.1166/jbn.2019.2681.
372 Vanillic Acid Suppresses HIF-1 Expression via Inhibition of mTOR/p70S6K/4E-BP1 and Raf/MEK/ERK Pathways in Human Colon Cancer HCT116 Cells.Int J Mol Sci. 2019 Jan 22;20(3):465. doi: 10.3390/ijms20030465.
373 Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling.Exp Cell Res. 2007 Feb 1;313(3):437-49. doi: 10.1016/j.yexcr.2006.09.030. Epub 2006 Oct 28.
374 Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-I beta/B10/gp130RB13-6) in human colon carcinoma.Int J Mol Med. 2003 Nov;12(5):763-6.
375 Construction of chimeric antigen receptormodified T cells targeting EpCAM and assessment of their antitumor effect on cancer cells.Mol Med Rep. 2019 Sep;20(3):2355-2364. doi: 10.3892/mmr.2019.10460. Epub 2019 Jul 3.
376 Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery.Int J Mol Sci. 2017 Feb 3;18(2):307. doi: 10.3390/ijms18020307.
377 EphA3 Downregulation by Hypermethylation Associated with Lymph Node Metastasis and TNM Stage in Colorectal Cancer.Dig Dis Sci. 2019 Jun;64(6):1514-1522. doi: 10.1007/s10620-018-5421-9. Epub 2018 Dec 17.
378 Genome wide association study to identify predictors for severe skin toxicity in colorectal cancer patients treated with cetuximab.PLoS One. 2018 Dec 17;13(12):e0208080. doi: 10.1371/journal.pone.0208080. eCollection 2018.
379 Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers.Clin Chem. 2004 Mar;50(3):490-9. doi: 10.1373/clinchem.2003.026849. Epub 2004 Jan 15.
380 Anti-MEK and Anti-EGFR mAbs in RAS-Mutant Metastatic Colorectal Cancer: Case Series and Rationale.Adv Ther. 2019 Jun;36(6):1480-1484. doi: 10.1007/s12325-019-00949-y. Epub 2019 Apr 12.
381 EphB4 promotes the proliferation, invasion, and angiogenesis of human colorectal cancer.Exp Mol Pathol. 2016 Jun;100(3):402-8. doi: 10.1016/j.yexmp.2016.03.011. Epub 2016 Apr 9.
382 Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes.Mutat Res. 2012 Jun 1;734(1-2):30-40. doi: 10.1016/j.mrfmmm.2012.04.002. Epub 2012 Apr 15.
383 Silencing of CD133 inhibits GLUT1-mediated glucose transport through downregulation of the HER3/Akt/mTOR pathway in colon cancer.FEBS Lett. 2020 Mar;594(6):1021-1035. doi: 10.1002/1873-3468.13686. Epub 2019 Nov 29.
384 RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.FEBS Lett. 2011 Aug 4;585(15):2537-44. doi: 10.1016/j.febslet.2011.07.005. Epub 2011 Jul 13.
385 Decreased expression of protease-activated receptor 4 in human gastric cancer.Int J Biochem Cell Biol. 2011 Sep;43(9):1277-83. doi: 10.1016/j.biocel.2011.05.008. Epub 2011 May 25.
386 A recombinant adenovirus vector encoding the light chain of human coagulation factor VII and IgG1 Fc fragment to targeting tissue factor for colorectal cancer immunotherapy in the mouse model.J Cancer Res Clin Oncol. 2013 Jun;139(6):1015-23. doi: 10.1007/s00432-013-1417-1. Epub 2013 Mar 15.
387 Challenge in the differentiation between attenuated familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer: case report with review of the literature.Am J Gastroenterol. 2002 Jul;97(7):1822-7. doi: 10.1111/j.1572-0241.2002.05850.x.
388 A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry.Hum Mutat. 2013 Jan;34(1):200-9. doi: 10.1002/humu.22213. Epub 2012 Oct 11.
389 Ex vivo antibody-dependent cellular cytotoxicity inducibility predicts efficacy of cetuximab.Cancer Immunol Res. 2015 May;3(5):567-74. doi: 10.1158/2326-6066.CIR-14-0188. Epub 2015 Mar 13.
390 Downregulation of the neonatal Fc receptor expression in non-small cell lung cancer tissue is associated with a poor prognosis.Oncotarget. 2016 Aug 23;7(34):54415-54429. doi: 10.18632/oncotarget.10074.
391 Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer.Int J Nanomedicine. 2018 Nov 15;13:7533-7548. doi: 10.2147/IJN.S170692. eCollection 2018.
392 Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer.Clin Genet. 2017 Nov;92(5):495-502. doi: 10.1111/cge.12968. Epub 2017 Aug 2.
393 Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells.Exp Cell Res. 2018 Aug 1;369(1):54-60. doi: 10.1016/j.yexcr.2018.05.005. Epub 2018 May 8.
394 Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors.Int J Cancer. 2018 Aug 15;143(4):886-896. doi: 10.1002/ijc.31366. Epub 2018 Mar 30.
395 Upregulation of Fibroblast Growth Factor 19 Is Associated with the Initiation of Colorectal Adenoma.Dig Dis. 2019;37(3):214-225. doi: 10.1159/000494454. Epub 2018 Dec 5.
396 A transforming gene, hst, found in NIH 3T3 cells transformed with DNA from three stomach cancers and a colon cancer.Jpn J Cancer Res. 1987 Apr;78(4):325-8.
397 Keratinocyte Growth Factor Regulation of Aryl Hydrocarbon Receptor Activation in Colorectal Cancer Cells.Dig Dis Sci. 2016 Feb;61(2):444-52. doi: 10.1007/s10620-015-3908-1. Epub 2015 Oct 29.
398 FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect.Oncogene. 2013 Apr 25;32(17):2140-9. doi: 10.1038/onc.2012.228. Epub 2012 Jun 11.
399 Fos-like antigen 2 (FOSL2) promotes metastasis in colon cancer. Exp Cell Res. 2018 Dec 15;373(1-2):57-61.
400 Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation.Integr Cancer Ther. 2019 Jan-Dec;18:1534735419846377. doi: 10.1177/1534735419846377.
401 Color-coded Imaging Distinguishes Cancer Cells, Stromal Cells, and Recombinant Cancer-stromal Cells in the Tumor Microenvironment During Metastasis.Anticancer Res. 2018 Aug;38(8):4417-4423. doi: 10.21873/anticanres.12743.
402 Formyl peptide receptor 2 mediated chemotherapeutics drug resistance in colon cancer cells.Eur Rev Med Pharmacol Sci. 2018 Jan;22(1):95-100. doi: 10.26355/eurrev_201801_14105.
403 Studying human disease genes in Caenorhabditis elegans: a molecular genetics laboratory project.CBE Life Sci Educ. 2012 Summer;11(2):165-79. doi: 10.1187/cbe-11-06-0045.
404 Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway.Int J Mol Med. 2002 Feb;9(2):107-12.
405 Overexpression of FZD7 is associated with poor survival in patients with colon cancer.Pathol Res Pract. 2019 Aug;215(8):152478. doi: 10.1016/j.prp.2019.152478. Epub 2019 May 27.
406 The roles and mechanisms of G3BP1 in tumour promotion. J Drug Target. 2019 Mar;27(3):300-305.
407 Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling.PLoS One. 2008 Apr 30;3(4):e2079. doi: 10.1371/journal.pone.0002079.
408 Genome-wide diet-gene interaction analyses for risk of colorectal cancer.PLoS Genet. 2014 Apr 17;10(4):e1004228. doi: 10.1371/journal.pgen.1004228. eCollection 2014 Apr.
409 Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways.Oncotarget. 2018 Jan 31;9(12):10650-10664. doi: 10.18632/oncotarget.24367. eCollection 2018 Feb 13.
410 Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression.Biochem Biophys Res Commun. 2001 Aug 17;286(2):406-13. doi: 10.1006/bbrc.2001.5399.
411 siRNA-targeted inhibition of growth hormone receptor in human colon cancer SW480 cells.World J Gastroenterol. 2013 Nov 28;19(44):8108-13. doi: 10.3748/wjg.v19.i44.8108.
412 Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways.Eur J Pharmacol. 2016 Apr 5;776:124-31. doi: 10.1016/j.ejphar.2016.02.044. Epub 2016 Feb 12.
413 Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.Oncotarget. 2016 Dec 6;7(49):80190-80207. doi: 10.18632/oncotarget.13376.
414 Synergistic inhibition of colon cancer growth by the combination of methylglyoxal and silencing of glyoxalase I mediated by the STAT1 pathway.Oncotarget. 2017 Jun 22;8(33):54838-54857. doi: 10.18632/oncotarget.18601. eCollection 2017 Aug 15.
415 Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.J Pathol. 2018 Oct;246(2):134-140. doi: 10.1002/path.5128. Epub 2018 Aug 21.
416 Identification of regulatory role of DNA methylation in colon cancer gene expression via systematic bioinformatics analysis.Medicine (Baltimore). 2017 Nov;96(47):e8487. doi: 10.1097/MD.0000000000008487.
417 Phosphoglucose isomerase enhances colorectal cancer metastasis.Int J Oncol. 2009 Nov;35(5):1117-21. doi: 10.3892/ijo_00000427.
418 Down-regulation of GPR137 expression inhibits proliferation of colon cancer cells. RETRACTED ARTICLESee: Retraction NoticeActa Biochim Biophys Sin (Shanghai). 2014 Nov;46(11):935-41.
419 Utility of G protein-coupled receptor 35 expression for predicting outcome in colon cancer.Tumour Biol. 2019 Jun;41(6):1010428319858885. doi: 10.1177/1010428319858885.
420 Extravirgin olive oil up-regulates CB?tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms.J Nutr Biochem. 2015 Mar;26(3):250-8. doi: 10.1016/j.jnutbio.2014.10.013. Epub 2014 Dec 3.
421 Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial-mesenchymal transition in colon cancer.J Cell Biochem. 2019 Apr;120(4):5583-5596. doi: 10.1002/jcb.27842. Epub 2018 Nov 13.
422 The miR-487b-3p/GRM3/TGF signaling axis is an important regulator of colon cancer tumorigenesis.Oncogene. 2017 Jun 15;36(24):3477-3489. doi: 10.1038/onc.2016.499. Epub 2017 Jan 23.
423 Lower Expression of Gelsolin in Colon Cancer and Its Diagnostic Value in Colon Cancer Patients.J Cancer. 2019 Jan 30;10(5):1288-1296. doi: 10.7150/jca.28529. eCollection 2019.
424 Overexpression of glutathione S-transferase and elevation of thiol pools in a multidrug-resistant human colon cancer cell line.Mol Pharmacol. 1992 Jan;41(1):69-75.
425 Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. Nat Commun. 2016 Oct 5;7:13084.
426 Advances in In-Silico based Predictive In-Vivo Profiling of Novel Potent -Glucuronidase Inhibitors.Curr Cancer Drug Targets. 2019;19(11):906-918. doi: 10.2174/1568009619666190320102238.
427 Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment.Oncotarget. 2018 Jun 19;9(47):28364-28378. doi: 10.18632/oncotarget.25342. eCollection 2018 Jun 19.
428 Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression.Cancer Cell. 2017 Apr 10;31(4):563-575.e5. doi: 10.1016/j.ccell.2017.03.006.
429 Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-A.Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3618-3628. doi: 10.1016/j.bbadis.2018.08.023. Epub 2018 Aug 18.
430 HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.Oncol Lett. 2017 Oct;14(4):4923-4929. doi: 10.3892/ol.2017.6818. Epub 2017 Aug 24.
431 Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.Biochem J. 2009 Jan 1;417(1):379-89. doi: 10.1042/BJ20081132.
432 Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway.Onco Targets Ther. 2019 Apr 2;12:2409-2419. doi: 10.2147/OTT.S194986. eCollection 2019.
433 Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.Oncoimmunology. 2017 Feb 10;6(3):e1290034. doi: 10.1080/2162402X.2017.1290034. eCollection 2017.
434 Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).Development. 2005 Jan;132(2):415-27. doi: 10.1242/dev.01579. Epub 2004 Dec 16.
435 A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition.Nat Biotechnol. 2001 May;19(5):434-9. doi: 10.1038/88099.
436 Correlation of ERK/MAPK signaling pathway with proliferation and apoptosis of colon cancer cells.Oncol Lett. 2019 Feb;17(2):2266-2270. doi: 10.3892/ol.2018.9857. Epub 2018 Dec 20.
437 Tissue microarray cytometry reveals positive impact of homeodomain interacting protein kinase 2 in colon cancer survival irrespective of p53 function.Am J Pathol. 2011 May;178(5):1986-98. doi: 10.1016/j.ajpath.2011.01.021.
438 Predictive value of different proportion of lesion HLA-G expression in colorectal cancer.Oncotarget. 2017 Nov 18;8(64):107441-107451. doi: 10.18632/oncotarget.22487. eCollection 2017 Dec 8.
439 KLF4 sensitizes the colon cancer cell HCT-15 to cisplatin by altering the expression of HMGB1 and hTERT.Life Sci. 2019 Mar 1;220:169-176. doi: 10.1016/j.lfs.2019.02.005. Epub 2019 Feb 2.
440 Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.Br J Cancer. 2017 Jun 6;116(12):1652-1659. doi: 10.1038/bjc.2017.139. Epub 2017 May 18.
441 Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer prevention.Sci Rep. 2019 Apr 17;9(1):6192. doi: 10.1038/s41598-019-42363-y.
442 microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.Oncogene. 2014 Oct 2;33(40):4847-56. doi: 10.1038/onc.2013.429. Epub 2013 Oct 28.
443 A novel long non-coding RNA from the HOXA6-HOXA5 locus facilitates colon cancer cell growth.BMC Cancer. 2019 Jun 3;19(1):532. doi: 10.1186/s12885-019-5715-0.
444 Graphene OxidePEGProtocatechuic Acid Nanocomposite Formulation with Improved Anticancer Properties.Nanomaterials (Basel). 2018 Oct 11;8(10):820. doi: 10.3390/nano8100820.
445 Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines.PLoS One. 2014 Aug 18;9(8):e105354. doi: 10.1371/journal.pone.0105354. eCollection 2014.
446 Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).Org Biomol Chem. 2017 Sep 20;15(36):7623-7629. doi: 10.1039/c7ob01584d.
447 Polymer mediated transport of the Hsp90 inhibitor LB76, a polar cyclic peptide, produces an Hsp90 cellular phenotype.Chem Commun (Camb). 2019 Apr 11;55(31):4515-4518. doi: 10.1039/c9cc00890j.
448 Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.Curr Top Med Chem. 2016;16(25):2765-78. doi: 10.2174/1568026616666160413141613.
449 Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer. Chem Biol Interact. 2018 Aug 1;291:16-28. doi: 10.1016/j.cbi.2018.06.001. Epub 2018 Jun 5.
450 Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients.Br J Cancer. 2003 Sep 15;89(6):1079-85. doi: 10.1038/sj.bjc.6601203.
451 Associations of ICOS and PD.1 Gene Variants with Colon Cancer Risk in The Iranian Population.Asian Pac J Cancer Prev. 2018 Mar 27;19(3):693-698. doi: 10.22034/APJCP.2018.19.3.693.
452 Polymorphisms in the ICOS/CD28-ICOSL pathway are related to capecitabine-based chemotherapy response in advanced colon cancer patients.Mol Immunol. 2018 Apr;96:78-82. doi: 10.1016/j.molimm.2018.02.017. Epub 2018 Mar 5.
453 Insights into Resistance Mechanisms of Inhibitors to Mps1 C604Y Mutation via a Comprehensive Molecular Modeling Study.Molecules. 2018 Jun 20;23(6):1488. doi: 10.3390/molecules23061488.
454 Changes Due to Ageing in the Glycan Structure of Alpha-2-Macroglobulin and Its Reactivity with Ligands.Protein J. 2019 Feb;38(1):23-29. doi: 10.1007/s10930-018-9806-6.
455 Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites.Cancer Causes Control. 2012 Jul;23(7):1127-38. doi: 10.1007/s10552-012-9981-2. Epub 2012 May 8.
456 The role of IGFBP-5 in mediating the anti-proliferation effect of tetrandrine in human colon cancer cells.Int J Oncol. 2015 Mar;46(3):1205-13. doi: 10.3892/ijo.2014.2800. Epub 2014 Dec 17.
457 Elevated expression of tumor necrosis factor-alpha signaling molecules in colonic tumors of Zucker obese (fa/fa) rats.Int J Cancer. 2010 Nov 1;127(9):2042-50. doi: 10.1002/ijc.25232.
458 Helminth-derived molecules inhibit colitis-associated colon cancer development through NF-B and STAT3 regulation.Int J Cancer. 2019 Dec 1;145(11):3126-3139. doi: 10.1002/ijc.32626. Epub 2019 Aug 30.
459 The immune microenvironment of the colorectal tumor: Involvement of immunity genes and microRNAs belonging to the TH17 pathway.Biochim Biophys Acta. 2015 Aug;1856(1):28-38. doi: 10.1016/j.bbcan.2015.04.001. Epub 2015 Apr 21.
460 Interleukin-1 receptor antagonist inhibits the expression of vascular endothelial growth factor in colorectal carcinoma.Oncology. 2005;68(2-3):138-45. doi: 10.1159/000086768. Epub 2005 Jul 4.
461 Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis.J Biol Chem. 2015 Sep 4;290(36):22212-24. doi: 10.1074/jbc.M115.644823. Epub 2015 Jul 24.
462 IL-21 Enhances the Development of Colitis-Associated Colon Cancer: Possible Involvement of Activation-Induced Cytidine Deaminase Expression.J Immunol. 2019 Jun 1;202(11):3326-3333. doi: 10.4049/jimmunol.1800550. Epub 2019 Apr 24.
463 Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway.Int J Mol Sci. 2019 Jul 15;20(14):3468. doi: 10.3390/ijms20143468.
464 IL-32 expression indicates unfavorable prognosis in patients with colon cancer.Oncol Lett. 2019 May;17(5):4655-4660. doi: 10.3892/ol.2019.10136. Epub 2019 Mar 12.
465 Dual enhancement of T and NK cell function by pulsatile inhibition of SHIP1 improves antitumor immunity and survival.Sci Signal. 2017 Oct 10;10(500):eaam5353. doi: 10.1126/scisignal.aam5353.
466 Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.Cell Rep. 2018 Dec 11;25(11):3036-3046.e6. doi: 10.1016/j.celrep.2018.11.050.
467 Hypermethylation of ITGA4, TFPI2 and VIMENTIN promoters is increased in inflamed colon tissue: putative risk markers for colitis-associated cancer.J Cancer Res Clin Oncol. 2015 Dec;141(12):2097-107. doi: 10.1007/s00432-015-1972-8. Epub 2015 Apr 23.
468 Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide.Int J Pharm. 2009 Jan 21;366(1-2):201-10. doi: 10.1016/j.ijpharm.2008.09.016. Epub 2008 Sep 19.
469 MiR-30a-5p Suppresses Tumor Metastasis of Human Colorectal Cancer by Targeting ITGB3.Cell Physiol Biochem. 2016;39(3):1165-76. doi: 10.1159/000447823. Epub 2016 Aug 31.
470 Tumor specific delivery and therapy mediate by integrin 6-target immunoliposomes for 6-siRNA in colon carcinoma.Oncotarget. 2016 Dec 20;7(51):85163-85175. doi: 10.18632/oncotarget.13209.
471 Long noncoding RNA ENST00000455974 plays an oncogenic role through up-regulating JAG2 in human DNA mismatch repair-proficient colon cancer.Biochem Biophys Res Commun. 2019 Jan 8;508(2):339-347. doi: 10.1016/j.bbrc.2018.11.088. Epub 2018 Nov 23.
472 Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer.Oncol Lett. 2019 Jan;17(1):159-164. doi: 10.3892/ol.2018.9569. Epub 2018 Oct 12.
473 Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.Am J Cancer Res. 2018 May 1;8(5):852-865. eCollection 2018.
474 Downregulation of the hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil.Chemotherapy. 2008;54(5):357-63. doi: 10.1159/000153655. Epub 2008 Sep 5.
475 Activity of voltage-gated K+ channels is associated with cell proliferation and Ca2+ influx in carcinoma cells of colon cancer.Life Sci. 1999;65(1):55-62. doi: 10.1016/s0024-3205(99)00218-0.
476 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.Cancer Res. 2016 Sep 1;76(17):5103-14. doi: 10.1158/0008-5472.CAN-15-2980. Epub 2016 Apr 20.
477 [Correlation of HERG K+ channel protein expression to chemosensitivity of tumor cells to doxorubicin and its modulation by erythromycin].Ai Zheng. 2005 Aug;24(8):924-9.
478 Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.Cell Rep. 2014 Jul 24;8(2):501-13. doi: 10.1016/j.celrep.2014.06.035. Epub 2014 Jul 17.
479 Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.Mol Cell. 2019 Jun 20;74(6):1250-1263.e6. doi: 10.1016/j.molcel.2019.04.009. Epub 2019 May 1.
480 The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells.J Cell Biochem. 2012 Apr;113(4):1368-76. doi: 10.1002/jcb.24009.
481 KDM5c inhibits multidrug resistance of colon cancer cell line by down-regulating ABCC1.Biomed Pharmacother. 2018 Nov;107:1205-1209. doi: 10.1016/j.biopha.2018.08.041. Epub 2018 Aug 29.
482 Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients.Mol Med. 2014 Mar 18;20(1):80-92. doi: 10.2119/molmed.2013.00151.
483 Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer.Biol Chem. 2014 Sep;395(9):1075-86. doi: 10.1515/hsz-2014-0142.
484 Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein.Oncotarget. 2019 Oct 22;10(58):6062-6078. doi: 10.18632/oncotarget.27153. eCollection 2019 Oct 22.
485 Chitosan nanoparticle-based delivery of fused NKG2D-IL-21 gene suppresses colon cancer growth in mice.Int J Nanomedicine. 2017 Apr 13;12:3095-3107. doi: 10.2147/IJN.S128032. eCollection 2017.
486 Relationship between LAPTM4B Gene Polymorphism and Prognosis of Patients following Tumor Resection for Colorectal and Esophageal Cancers.PLoS One. 2016 Jul 8;11(7):e0158715. doi: 10.1371/journal.pone.0158715. eCollection 2016.
487 Recognition of the Lck tyrosine kinase as a tumor antigen by cytotoxic T lymphocytes of cancer patients with distant metastases.Eur J Immunol. 2001 Feb;31(2):323-32. doi: 10.1002/1521-4141(200102)31:2<323::aid-immu323>3.0.co;2-0.
488 Reduced Lipocalin 2 Expression Contributes to Vincristine Resistance in Human Colon Cancer Cells.Recent Pat Anticancer Drug Discov. 2018;13(2):248-254. doi: 10.2174/1574892813666171221120504.
489 Prognostic impact of mRNA levels of LGR5 transcript variants in OSCC patients.BMC Cancer. 2019 Feb 15;19(1):155. doi: 10.1186/s12885-019-5327-8.
490 Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin.JCI Insight. 2018 Jul 26;3(14):e121221. doi: 10.1172/jci.insight.121221. eCollection 2018 Jul 26.
491 Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.Int J Oncol. 2011 Aug;39(2):337-44. doi: 10.3892/ijo.2011.1050. Epub 2011 May 23.
492 Downregulation of LIMK1-ADF/cofilin by DADS inhibits the migration and invasion of colon cancer.Sci Rep. 2017 Mar 30;7:45624. doi: 10.1038/srep45624.
493 Single nucleotide polymorphisms within MicroRNAs, MicroRNA targets, and MicroRNA biogenesis genes and their impact on colorectal cancer survival.Genes Chromosomes Cancer. 2017 Apr;56(4):285-295. doi: 10.1002/gcc.22434. Epub 2017 Jan 25.
494 Transcriptional regulation of the human placental-like alkaline phosphatase gene and mechanisms involved in its induction by sodium butyrate.Cancer Res. 1992 Jun 15;52(12):3378-83.
495 Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.Oncotarget. 2016 May 26;8(36):60015-60024. doi: 10.18632/oncotarget.9623. eCollection 2017 Sep 1.
496 LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.Clin Cancer Res. 2015 Nov 1;21(21):4892-902. doi: 10.1158/1078-0432.CCR-14-3096. Epub 2015 Jul 23.
497 MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.Gastroenterology. 2011 Mar;140(3):924-34. doi: 10.1053/j.gastro.2010.11.054. Epub 2010 Dec 4.
498 Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cells.Tumour Biol. 2012 Dec;33(6):1899-905. doi: 10.1007/s13277-012-0450-z. Epub 2012 Jul 5.
499 Platelets subvert T cell immunity against cancer via GARP-TGF axis.Sci Immunol. 2017 May 5;2(11):eaai7911. doi: 10.1126/sciimmunol.aai7911.
500 Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2.Oncogene. 2015 Aug 20;34(34):4519-30. doi: 10.1038/onc.2014.386. Epub 2014 Dec 8.
501 Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7859-64. doi: 10.1073/pnas.1332465100. Epub 2003 Jun 16.
502 V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer.Cancer Discov. 2019 Sep;9(9):1182-1191. doi: 10.1158/2159-8290.CD-19-0356. Epub 2019 Jun 21.
503 Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells.Apoptosis. 2013 Oct;18(10):1163-74. doi: 10.1007/s10495-013-0883-x.
504 Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.Cancer Res. 2016 Feb 1;76(3):724-35. doi: 10.1158/0008-5472.CAN-15-0701-T. Epub 2015 Dec 4.
505 ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis.JCI Insight. 2017 Sep 21;2(18):e91828. doi: 10.1172/jci.insight.91828. eCollection 2017 Sep 21.
506 The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors.Saudi J Gastroenterol. 2018 Jan-Feb;24(1):37-45. doi: 10.4103/sjg.SJG_270_17.
507 Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.Br J Cancer. 2009 May 5;100(9):1415-24. doi: 10.1038/sj.bjc.6605021. Epub 2009 Apr 7.
508 Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.Oncogene. 2015 Feb 26;34(9):1150-9. doi: 10.1038/onc.2014.40. Epub 2014 Mar 24.
509 Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells.Am J Pathol. 2003 May;162(5):1503-13. doi: 10.1016/S0002-9440(10)64283-6.
510 Expression of methionine adenosyltransferase 2A in renal cell carcinomas and potential mechanism for kidney carcinogenesis.BMC Cancer. 2014 Mar 17;14:196. doi: 10.1186/1471-2407-14-196.
511 Myc-Associated Zinc Finger Protein Regulates the Proinflammatory Response in Colitis and Colon Cancer via STAT3 Signaling.Mol Cell Biol. 2018 Oct 29;38(22):e00386-18. doi: 10.1128/MCB.00386-18. Print 2018 Nov 15.
512 Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P(2) and S1P(3) Expression in ColonCancer.Clin Colorectal Cancer. 2018 Jun;17(2):e171-e182. doi: 10.1016/j.clcc.2017.11.004. Epub 2017 Nov 21.
513 Correlations of MC4R and MSH2 expression with obesity in colon cancer patients.Eur Rev Med Pharmacol Sci. 2017 May;21(9):2108-2113.
514 Mdm2-P53 Interaction Inhibitor with Cisplatin Enhances Apoptosis in Colon and Prostate Cancer Cells In-Vitro.Asian Pac J Cancer Prev. 2019 Nov 1;20(11):3341-3351. doi: 10.31557/APJCP.2019.20.11.3341.
515 Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression.Nat Commun. 2018 Jul 3;9(1):2574. doi: 10.1038/s41467-018-04999-8.
516 Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.Chem Biol Interact. 2009 Jan 27;177(2):128-36. doi: 10.1016/j.cbi.2008.10.047. Epub 2008 Nov 5.
517 CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5.
518 DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility.Int J Cancer. 2020 Jan 15;146(2):363-372. doi: 10.1002/ijc.32516. Epub 2019 Jul 4.
519 USP10 regulates Musashi-2 stability via deubiquitination and promotes tumour proliferation in colon cancer.FEBS Lett. 2019 Feb;593(4):406-413. doi: 10.1002/1873-3468.13323. Epub 2019 Jan 16.
520 Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential.Oncogene. 2003 Jan 16;22(2):186-97. doi: 10.1038/sj.onc.1206075.
521 Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk.J Nutrigenet Nutrigenomics. 2008;1(4):196-204. doi: 10.1159/000136651. Epub 2008 Jun 2.
522 Overexpression of MUC15 activates extracellular signal-regulated kinase 1/2 and promotes the oncogenic potential of human colon cancer cells.Carcinogenesis. 2009 Aug;30(8):1452-8. doi: 10.1093/carcin/bgp137. Epub 2009 Jun 11.
523 Abrogation of MUC5AC Expression Contributes to the Apoptosis and Cell Cycle Arrest of Colon Cancer Cells.Cancer Biother Radiopharm. 2016 Sep;31(7):261-7. doi: 10.1089/cbr.2016.2054.
524 A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S](2+) cluster.Nat Chem. 2018 Aug;10(8):873-880. doi: 10.1038/s41557-018-0068-x. Epub 2018 Jun 18.
525 Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers.Genes Chromosomes Cancer. 2006 Dec;45(12):1143-54. doi: 10.1002/gcc.20378.
526 Overexpression of MYC binding protein promotes invasion and migration in gastric cancer.Oncol Lett. 2018 Apr;15(4):5243-5249. doi: 10.3892/ol.2018.7944. Epub 2018 Feb 2.
527 Single nucleotide polymorphisms in the MYLKP1 pseudogene are associated with increased colon cancer risk in African Americans.PLoS One. 2018 Aug 30;13(8):e0200916. doi: 10.1371/journal.pone.0200916. eCollection 2018.
528 Defective IL-23/IL-17 Axis Protects p47phox-/- Mice from Colon Cancer.Front Immunol. 2017 Jan 27;8:44. doi: 10.3389/fimmu.2017.00044. eCollection 2017.
529 Nucleolin facilitates nuclear retention of an ultraconserved region containing TRA24 and accelerates colon cancer cell growth.Oncotarget. 2018 Jun 1;9(42):26817-26833. doi: 10.18632/oncotarget.25510. eCollection 2018 Jun 1.
530 NCOA4-RET fusion in colorectal cancer: Therapeutic challenge using patient-derived tumor cell lines.J Cancer. 2018 Jul 30;9(17):3032-3037. doi: 10.7150/jca.26256. eCollection 2018.
531 Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway.J Virol. 2017 Apr 28;91(10):e02191-16. doi: 10.1128/JVI.02191-16. Print 2017 May 15.
532 The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy.Korean J Physiol Pharmacol. 2018 Nov;22(6):617-625. doi: 10.4196/kjpp.2018.22.6.617. Epub 2018 Oct 25.
533 Panitumumab interaction with TAS-102 leads to combinational anticancer effects via blocking of EGFR-mediated tumor response to trifluridine.Mol Oncol. 2017 Aug;11(8):1065-1077. doi: 10.1002/1878-0261.12074. Epub 2017 May 30.
534 IBK and NFB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family Registry.Carcinogenesis. 2013 Jan;34(1):79-85. doi: 10.1093/carcin/bgs296. Epub 2012 Sep 22.
535 SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis.Cancer Res. 2007 Oct 1;67(19):9568-76. doi: 10.1158/0008-5472.CAN-06-2707.
536 The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis.J Immunol. 2015 Apr 1;194(7):3369-80. doi: 10.4049/jimmunol.1402098. Epub 2015 Feb 27.
537 The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.Cell Rep. 2016 Mar 22;14(11):2562-75. doi: 10.1016/j.celrep.2016.02.064. Epub 2016 Mar 10.
538 Thioredoxin-like protein 2 is overexpressed in colon cancer and promotes cancer cell metastasis by interaction with ran.Antioxid Redox Signal. 2013 Sep 20;19(9):899-911. doi: 10.1089/ars.2012.4736. Epub 2013 Mar 4.
539 NOTCH1 activates the Wnt/-catenin signaling pathway in colon cancer.Oncotarget. 2017 Jul 25;8(36):60378-60389. doi: 10.18632/oncotarget.19534. eCollection 2017 Sep 1.
540 Proteomic and functional investigation of the colon cancer relapse-associated genes NOX4 and ITGA3.J Proteome Res. 2014 Nov 7;13(11):4910-8. doi: 10.1021/pr500557n. Epub 2014 Aug 18.
541 Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids.Oncotarget. 2018 Jun 19;9(47):28717-28730. doi: 10.18632/oncotarget.25617. eCollection 2018 Jun 19.
542 Anthocyanin Encapsulated by Ferulic Acid-Grafted-Maltodextrin (FA-g-MD) Microcapsules Potentially Improved its Free Radical Scavenging Capabilities Against H(2)O(2)-Induced Oxidative Stress.Molecules. 2019 Apr 23;24(8):1596. doi: 10.3390/molecules24081596.
543 Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells.J Nutr. 2016 Feb;146(2):236-42. doi: 10.3945/jn.115.216580. Epub 2015 Nov 25.
544 Decreased transcription-coupled nucleotide excision repair capacity is associated with increased p53- and MLH1-independent apoptosis in response to cisplatin.BMC Cancer. 2010 May 14;10:207. doi: 10.1186/1471-2407-10-207.
545 Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy.Eur J Cancer. 2013 Nov;49(16):3420-30. doi: 10.1016/j.ejca.2013.06.001. Epub 2013 Jun 25.
546 MicroRNA-374b reduces the proliferation and invasion of colon cancer cells by regulation of LRH-1/Wnt signaling.Gene. 2018 Feb 5;642:354-361. doi: 10.1016/j.gene.2017.11.019. Epub 2017 Nov 8.
547 Lymphangiogenic Gene Expression Is Associated With Lymph Node Recurrence and Poor Prognosis After Partial Hepatectomy for Colorectal Liver Metastasis.Ann Surg. 2017 Nov;266(5):765-771. doi: 10.1097/SLA.0000000000002430.
548 Analysis of risk factors for colon cancer progression.Onco Targets Ther. 2019 May 22;12:3991-4000. doi: 10.2147/OTT.S207390. eCollection 2019.
549 Aberrant methylation of the netrin-1 receptor genes UNC5C and DCC detected in advanced colorectal cancer.World J Surg. 2009 May;33(5):1053-7. doi: 10.1007/s00268-008-9909-x.
550 ypoxia-inducible factor 1- promotes colon cell proliferation and migration by upregulating AMPK-related protein kinase 5 under hypoxic conditions.Oncol Lett. 2018 Mar;15(3):3639-3645. doi: 10.3892/ol.2018.7748. Epub 2018 Jan 8.
551 Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells.Biochem Biophys Res Commun. 2015 Mar 27;459(1):29-35. doi: 10.1016/j.bbrc.2015.02.043. Epub 2015 Feb 19.
552 Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.Cancer Res. 2018 Aug 1;78(15):4303-4315. doi: 10.1158/0008-5472.CAN-18-0116. Epub 2018 May 31.
553 Targeting LOX-1 Inhibits Colorectal Cancer Metastasis in an Animal Model.Front Oncol. 2019 Sep 19;9:927. doi: 10.3389/fonc.2019.00927. eCollection 2019.
554 TRPC1 and ORAI1 channels in colon cancer.Cell Calcium. 2019 Jul;81:59-66. doi: 10.1016/j.ceca.2019.06.003. Epub 2019 Jun 7.
555 Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer.PLoS One. 2009 Aug 7;4(8):e6555. doi: 10.1371/journal.pone.0006555.
556 PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer.Cancer Cell Int. 2019 Nov 5;19:277. doi: 10.1186/s12935-019-0999-3. eCollection 2019.
557 PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth.Cell Death Dis. 2017 May 25;8(5):e2820. doi: 10.1038/cddis.2017.85.
558 Biophysical characterization and structural determination of the potent cytotoxic Psathyrella asperospora lectin.Proteins. 2017 May;85(5):969-975. doi: 10.1002/prot.25265. Epub 2017 Mar 7.
559 The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.Apoptosis. 2011 Dec;16(12):1285-94. doi: 10.1007/s10495-011-0648-3.
560 The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.J Pathol. 2018 Jan;244(1):36-48. doi: 10.1002/path.4986. Epub 2017 Nov 27.
561 Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer.Arch Med Sci. 2019 May;15(3):559-569. doi: 10.5114/aoms.2019.84732. Epub 2019 Apr 30.
562 Cinnamtannin B-1 inhibits cell survival molecules and induces apoptosis in colon cancer.Int J Oncol. 2018 Oct;53(4):1442-1454. doi: 10.3892/ijo.2018.4489. Epub 2018 Jul 19.
563 Combination of attenuated Salmonella carrying PD-1 siRNA with nifuroxazide for colon cancer therapy.J Cell Biochem. 2020 Feb;121(2):1973-1985. doi: 10.1002/jcb.29432. Epub 2019 Nov 6.
564 The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.PLoS Genet. 2018 Sep 6;14(9):e1007611. doi: 10.1371/journal.pgen.1007611. eCollection 2018 Sep.
565 Phosphodiesterase-5 inhibition suppresses colonic inflammation-induced tumorigenesis via blocking the recruitment of MDSC.Am J Cancer Res. 2017 Jan 1;7(1):41-52. eCollection 2017.
566 Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.Nutr Cancer. 2011 Nov;63(8):1226-34. doi: 10.1080/01635581.2011.607545. Epub 2011 Oct 14.
567 Evidence for various 20q status using allelotyping, CGH arrays, and quantitative PCR in distal CIN colon cancers.Cancer Lett. 2009 Sep 18;282(2):195-204. doi: 10.1016/j.canlet.2009.03.012. Epub 2009 Apr 25.
568 PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells.Int J Mol Sci. 2019 Oct 30;20(21):5415. doi: 10.3390/ijms20215415.
569 CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling.Int J Colorectal Dis. 2013 Nov;28(11):1479-87. doi: 10.1007/s00384-013-1712-y. Epub 2013 May 7.
570 Pleckstrin homology domain-containing protein PHLDB3 supports cancer growth via a negative feedback loop involving p53. Nat Commun. 2016 Dec 23;7:13755.
571 The effect of omentin-1 on the proliferation and apoptosis of colon cancer stem cells and the potential mechanism.J BUON. 2019 Jan-Feb;24(1):91-98.
572 NF-B potentiates tumor growth by suppressing a novel target LPTS.Cell Commun Signal. 2017 Oct 10;15(1):39. doi: 10.1186/s12964-017-0196-8.
573 Circular RNA PIP5K1A promotes colon cancer development through inhibiting miR-1273a.World J Gastroenterol. 2019 Sep 21;25(35):5300-5309. doi: 10.3748/wjg.v25.i35.5300.
574 PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway.Mol Cancer. 2018 Jan 24;17(1):13. doi: 10.1186/s12943-017-0747-z.
575 HT-29 human colon cancer cell proliferation is regulated by cytosolic phospholipase A(2) dependent PGE(2)via both PKA and PKB pathways.Biochim Biophys Acta. 2012 Sep;1821(9):1224-34. doi: 10.1016/j.bbalip.2012.06.005. Epub 2012 Jun 19.
576 Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter.BioDrugs. 2010 Apr 1;24(2):131-46. doi: 10.2165/11530840-000000000-00000.
577 Phosphoinositide-specific phospholipase C1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.Sci Rep. 2017 Oct 24;7(1):13912. doi: 10.1038/s41598-017-13334-y.
578 PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.Nat Commun. 2018 Mar 16;9(1):1106. doi: 10.1038/s41467-018-03494-4.
579 Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability.Cell Death Dis. 2019 Jul 29;10(8):570. doi: 10.1038/s41419-019-1778-8.
580 Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells.Biochem Biophys Res Commun. 2003 Feb 14;301(3):675-9. doi: 10.1016/s0006-291x(03)00022-6.
581 Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells.Mol Cancer Res. 2014 Oct;12(10):1407-15. doi: 10.1158/1541-7786.MCR-14-0246. Epub 2014 Jul 16.
582 Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-/ overexpression.J Natl Cancer Inst. 2014 Apr;106(4):dju052. doi: 10.1093/jnci/dju052. Epub 2014 Mar 28.
583 Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPAR partial agonists.Sci Rep. 2019 Apr 1;9(1):5434. doi: 10.1038/s41598-019-41765-2.
584 Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1).Cancer Lett. 2004 Jan 8;203(1):25-33. doi: 10.1016/j.canlet.2003.08.024.
585 Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans.Hepatology. 2011 Nov;54(5):1661-78. doi: 10.1002/hep.24539.
586 Effect of ganoderic acid D on colon cancer Warburg effect: Role of SIRT3/cyclophilin D.Eur J Pharmacol. 2018 Apr 5;824:72-77. doi: 10.1016/j.ejphar.2018.01.026. Epub 2018 Jan 31.
587 Silencing of PPMD1 inhibits proliferation of human colon cancer cells via induction of apoptosis and cell cycle arrest.J BUON. 2019 Jul-Aug;24(4):1464-1469.
588 Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.Clin Cancer Res. 2015 Aug 15;21(16):3695-704. doi: 10.1158/1078-0432.CCR-14-2457. Epub 2015 May 5.
589 In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells.Food Funct. 2017 Oct 18;8(10):3553-3562. doi: 10.1039/c7fo00895c.
590 SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk.PLoS One. 2015 Dec 2;10(12):e0143894. doi: 10.1371/journal.pone.0143894. eCollection 2015.
591 Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer.Oncotarget. 2017 Aug 12;8(45):78811-78824. doi: 10.18632/oncotarget.20229. eCollection 2017 Oct 3.
592 Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.Mol Carcinog. 2017 Jul;56(7):1816-1824. doi: 10.1002/mc.22640. Epub 2017 Mar 10.
593 Two proliferation-related proteins, TYMS and PGK1, could be new cytotoxic T lymphocyte-directed tumor-associated antigens of HLA-A2+ colon cancer.Clin Cancer Res. 2004 Sep 1;10(17):5828-36. doi: 10.1158/1078-0432.CCR-04-0350.
594 New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines.Eur J Med Chem. 2017 Dec 1;141:61-72. doi: 10.1016/j.ejmech.2017.09.053. Epub 2017 Sep 27.
595 Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells.Oncol Rep. 2018 Jul;40(1):536-544. doi: 10.3892/or.2018.6402. Epub 2018 Apr 25.
596 Endocrine gland-derived vascular endothelial growth factor strengthens cell invasion ability via prokineticin receptor 2 in colon cancer cell lines.Oncol Rep. 2013 Feb;29(2):459-63. doi: 10.3892/or.2012.2124. Epub 2012 Nov 6.
597 Expression of a thioredoxin-related protein-1 is induced by prostaglandin E(2).Int J Cancer. 2006 Apr 1;118(7):1670-9. doi: 10.1002/ijc.21572.
598 The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer.Cancer Res. 2011 Dec 1;71(23):7145-54. doi: 10.1158/0008-5472.CAN-10-1883. Epub 2011 Oct 28.
599 MicroRNA-1254 inhibits the migration of colon adenocarcinoma cells by targeting PSMD10.J Dig Dis. 2017 Mar;18(3):169-178. doi: 10.1111/1751-2980.12463.
600 Prostaglandin E?regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells.Biochem Pharmacol. 2011 Feb 1;81(3):379-87. doi: 10.1016/j.bcp.2010.11.001. Epub 2010 Nov 9.
601 Upregulation of C-C chemokine receptor type 7 expression by membrane-associated prostaglandin E synthase-1/prostaglandin E2 requires glycogen synthase kinase 3-mediated signal transduction in colon cancer cells.Mol Med Rep. 2015 Nov;12(5):7169-75. doi: 10.3892/mmr.2015.4290. Epub 2015 Sep 3.
602 Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps.Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):502-8. doi: 10.1158/1055-9965.EPI-05-0804.
603 WiNTRLINC1/ASCL2/c-Myc Axis Characteristics of Colon Cancer with Differentiated Histology at Young Onset and Essential for Cell Viability.Ann Surg Oncol. 2019 Dec;26(13):4826-4834. doi: 10.1245/s10434-019-07780-3. Epub 2019 Sep 23.
604 pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1).PLoS One. 2014 Jan 22;9(1):e85796. doi: 10.1371/journal.pone.0085796. eCollection 2014.
605 Cytokine associated sensitivity of colon carcinoma cells to FasR-mediated cytotoxicity of CTL.Asian J Surg. 2002 Jan;25(1):89-97.
606 B-cell leukemia protein-2 and peptide YY chemotherapy resistance in colon cancer.Am J Surg. 1999 Nov;178(5):411-4. doi: 10.1016/s0002-9610(99)00209-3.
607 MicroRNA-193b acts as a tumor suppressor in colon cancer progression via targeting RAB22A.Exp Ther Med. 2019 May;17(5):3921-3928. doi: 10.3892/etm.2019.7435. Epub 2019 Mar 26.
608 RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition.Cancer Cell Int. 2017 Nov 28;17:111. doi: 10.1186/s12935-017-0483-x. eCollection 2017.
609 Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.Cell Death Dis. 2015 Apr 23;6(4):e1729. doi: 10.1038/cddis.2015.104.
610 miR-223 promotes colon cancer by directly targeting p120 catenin.Oncotarget. 2017 Jul 25;8(38):63764-63779. doi: 10.18632/oncotarget.19541. eCollection 2017 Sep 8.
611 Overexpression of Reg4, alone or combined with MMP-7 overexpression, is predictive of poor prognosis in colorectal cancer.Oncol Rep. 2015 Jan;33(1):320-8. doi: 10.3892/or.2014.3559. Epub 2014 Oct 22.
612 Expression of RNA-binding Motif Protein 3 (RBM3) and Cold-inducible RNA-binding protein (CIRP) Is Associated with Improved Clinical Outcome in Patients with Colon Cancer.Anticancer Res. 2017 Apr;37(4):1779-1785. doi: 10.21873/anticanres.11511.
613 Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.Cell Death Dis. 2015 Feb 12;6(2):e1636. doi: 10.1038/cddis.2015.16.
614 RNASEL mutation screening and association study in Ashkenazi and non-Ashkenazi prostate cancer patients.Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):474-9. doi: 10.1158/1055-9965.EPI-05-0606.
615 High hRFI expression correlates with resistance to fluoropyrimidines in human colon cancer cell lines and in xenografts.J Exp Clin Cancer Res. 2005 Sep;24(3):397-403.
616 Comparative genomics on ROR1 and ROR2 orthologs.Oncol Rep. 2005 Nov;14(5):1381-4. doi: 10.3892/or.14.5.1381.
617 Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.Molecules. 2017 Oct 3;22(10):1657. doi: 10.3390/molecules22101657.
618 Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase.Cancer Res. 2006 Jul 1;66(13):6497-502. doi: 10.1158/0008-5472.CAN-05-4462.
619 Rsf-1 overexpression correlates with poor prognosis and cell proliferation in colon cancer.Tumour Biol. 2012 Oct;33(5):1485-91. doi: 10.1007/s13277-012-0399-y. Epub 2012 Apr 20.
620 R-Spondin1/LGR5 Activates TGF Signaling and Suppresses Colon Cancer Metastasis.Cancer Res. 2017 Dec 1;77(23):6589-6602. doi: 10.1158/0008-5472.CAN-17-0219. Epub 2017 Sep 22.
621 Dentatin exerts anticancer effects on human colon cancer cell lines via cell cycle arrest, autophagy, inhibition of cell migration and JAK/STAT signalling pathway.J BUON. 2019 Jul-Aug;24(4):1488-1493.
622 Oncogenic potential of truncated RXR during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling.Nat Commun. 2019 Apr 1;10(1):1463. doi: 10.1038/s41467-019-09375-8.
623 Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR activation.J Exp Med. 2013 Nov 18;210(12):2675-92. doi: 10.1084/jem.20122292. Epub 2013 Nov 4.
624 S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer.J Oncol. 2018 Jul 9;2018:1828791. doi: 10.1155/2018/1828791. eCollection 2018.
625 The effect of S100A6 on nuclear translocation of CacyBP/SIP in colon cancer cells.PLoS One. 2018 Mar 13;13(3):e0192208. doi: 10.1371/journal.pone.0192208. eCollection 2018.
626 Clinical and biochemical relevance of monounsaturated fatty acid metabolism targeting strategy for cancer stem cell elimination in colon cancer.Biochem Biophys Res Commun. 2019 Oct 29;519(1):100-105. doi: 10.1016/j.bbrc.2019.08.137. Epub 2019 Aug 31.
627 Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.Sci Rep. 2015 Jun 22;5:11541. doi: 10.1038/srep11541.
628 Proteoglycans as potential microenvironmental biomarkers for colon cancer.Cell Tissue Res. 2015 Sep;361(3):833-44. doi: 10.1007/s00441-015-2141-8. Epub 2015 Feb 26.
629 Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.PLoS One. 2017 Mar 10;12(3):e0173747. doi: 10.1371/journal.pone.0173747. eCollection 2017.
630 Semaphoring 4D is required for the induction of antioxidant stress and anti-inflammatory effects of dihydromyricetin in colon cancer.Int Immunopharmacol. 2019 Feb;67:220-230. doi: 10.1016/j.intimp.2018.12.025. Epub 2018 Dec 15.
631 SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors.Cancer Lett. 2011 Oct 1;309(1):78-84. doi: 10.1016/j.canlet.2011.05.019. Epub 2011 Jun 12.
632 Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer.Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1082-6. doi: 10.1073/pnas.93.3.1082.
633 Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1 via the mTOR/p70S6K/4E-BP1 and MAPK pathways.J Ethnopharmacol. 2017 May 5;203:27-38. doi: 10.1016/j.jep.2017.03.033. Epub 2017 Mar 21.
634 SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patients.World J Gastrointest Oncol. 2019 Aug 15;11(8):589-598. doi: 10.4251/wjgo.v11.i8.589.
635 Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model.Mol Carcinog. 2016 May;55(5):600-10. doi: 10.1002/mc.22306. Epub 2015 Mar 14.
636 Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase.Oncogene. 2019 Jun;38(24):4788-4803. doi: 10.1038/s41388-019-0758-x. Epub 2019 Feb 28.
637 Risk of gastrointestinal cancers in patients with cystic fibrosis: a systematic review and meta-analysis.Lancet Oncol. 2018 Jun;19(6):758-767. doi: 10.1016/S1470-2045(18)30188-8. Epub 2018 Apr 26.
638 Prognostic and clinicopathological value of SIRT3 expression in various cancers: a systematic review and meta-analysis.Onco Targets Ther. 2018 Apr 13;11:2157-2167. doi: 10.2147/OTT.S157836. eCollection 2018.
639 Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.Carcinogenesis. 2015 Oct;36(10):1193-200. doi: 10.1093/carcin/bgv107. Epub 2015 Jul 25.
640 Specific detection of sialyl Lewis X determinant carried on the mucin GlcNAcbeta1-->6GalNAcalpha core structure as a tumor-associated antigen.Biochem Biophys Res Commun. 1998 Jun 18;247(2):514-7. doi: 10.1006/bbrc.1998.8824.
641 Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing.Cell Res. 2014 Jun;24(6):701-12. doi: 10.1038/cr.2014.43. Epub 2014 Apr 4.
642 Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy.Br J Cancer. 2002 Apr 22;86(8):1262-9. doi: 10.1038/sj.bjc.6600264.
643 Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression.BMC Complement Altern Med. 2014 Oct 15;14:401. doi: 10.1186/1472-6882-14-401.
644 Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.Cancer Res. 2005 Feb 1;65(3):887-97.
645 Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines. Biol Pharm Bull. 2012;35(3):301-7.
646 CD44-SLC1A2 fusion transcripts in primary colorectal cancer.Pathol Oncol Res. 2015 Jul;21(3):759-64. doi: 10.1007/s12253-014-9887-2. Epub 2015 Jan 10.
647 Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAF(V600E) In Vivo.Mol Imaging Biol. 2017 Jun;19(3):421-428. doi: 10.1007/s11307-016-1008-z.
648 Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses.Biomark Res. 2018 Jun 13;6:17. doi: 10.1186/s40364-018-0133-z. eCollection 2018.
649 L-Ascorbic acid can abrogate SVCT-2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells.Free Radic Biol Med. 2016 Jun;95:200-8. doi: 10.1016/j.freeradbiomed.2016.03.009. Epub 2016 Mar 22.
650 Differential expression of hENT1 and hENT2 in colon cancer cell lines.Genet Mol Res. 2017 Feb 16;16(1). doi: 10.4238/gmr16019549.
651 Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer.ACS Nano. 2018 Jun 26;12(6):5253-5265. doi: 10.1021/acsnano.7b08499. Epub 2018 Jun 8.
652 EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases.Oncotarget. 2017 Sep 16;8(54):92195-92208. doi: 10.18632/oncotarget.21028. eCollection 2017 Nov 3.
653 Expression of OATP family members in hormone-related cancers: potential markers of progression.PLoS One. 2011;6(5):e20372. doi: 10.1371/journal.pone.0020372. Epub 2011 May 19.
654 Possible role of nuclear -catenin in resistance to preoperative chemoradiotherapy in locally advanced rectal cancer.Histopathology. 2017 Aug;71(2):227-237. doi: 10.1111/his.13227. Epub 2017 May 22.
655 Liver acid sphingomyelinase inhibits growth of metastatic colon cancer.J Clin Invest. 2013 Feb;123(2):834-43. doi: 10.1172/JCI65188. Epub 2013 Jan 9.
656 SMYD2-OE promotes oxaliplatin resistance in colon cancer through MDR1/P-glycoprotein via MEK/ERK/AP1 pathway.Onco Targets Ther. 2019 Apr 8;12:2585-2594. doi: 10.2147/OTT.S186806. eCollection 2019.
657 Effects of -synuclein on the tumorigenicity and metastasis of colon cancer SW1116 cells in vitro and in vivo.Oncol Rep. 2013 Nov;30(5):2161-70. doi: 10.3892/or.2013.2688. Epub 2013 Aug 22.
658 B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).PLoS One. 2011;6(6):e21102. doi: 10.1371/journal.pone.0021102. Epub 2011 Jun 27.
659 Baicalin induces apoptosis in SW480 cells through downregulation of the SP1 transcription factor.Anticancer Drugs. 2019 Feb;30(2):153-158. doi: 10.1097/CAD.0000000000000708.
660 PDEF is a negative regulator of colon cancer cell growth and migration.J Cell Biochem. 2009 Dec 15;108(6):1389-98. doi: 10.1002/jcb.22371.
661 Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXR by K48/K63-linked polyubiquitination.Oncotarget. 2017 Jun 13;8(24):39605-39617. doi: 10.18632/oncotarget.17174.
662 Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis.Cancer Res. 2005 May 15;65(10):4228-37. doi: 10.1158/0008-5472.CAN-04-4585.
663 Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.Biomed Res Int. 2015;2015:690721. doi: 10.1155/2015/690721. Epub 2015 Oct 25.
664 The many faces of SRPK1.J Pathol. 2017 Mar;241(4):437-440. doi: 10.1002/path.4846. Epub 2017 Feb 1.
665 SRPK2 promotes the growth and migration of the colon cancer cells.Gene. 2016 Jul 15;586(1):41-7. doi: 10.1016/j.gene.2016.03.051. Epub 2016 Apr 12.
666 Promoter hypermethylation-related reduced somatostatin production promotes uncontrolled cell proliferation in colorectal cancer.PLoS One. 2015 Feb 27;10(2):e0118332. doi: 10.1371/journal.pone.0118332. eCollection 2015.
667 Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells.BMC Cancer. 2016 Dec 7;16(1):941. doi: 10.1186/s12885-016-2969-7.
668 Oncolytic vaccinia virus expressing the human somatostatin receptor SSTR2: molecular imaging after systemic delivery using 111In-pentetreotide.Mol Ther. 2004 Sep;10(3):553-61. doi: 10.1016/j.ymthe.2004.06.158.
669 Quantitation of membrane type serine protease 1 (MT-SP1) in transformed and normal cells.Biol Chem. 2003 Feb;384(2):257-66. doi: 10.1515/BC.2003.029.
670 Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. Cancer Immunol Res. 2017 May;5(5):385-396.
671 SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.Immunity. 2018 Sep 18;49(3):515-530.e5. doi: 10.1016/j.immuni.2018.08.024.
672 Upregulation of HRD1 promotes cell migration and invasion in colon cancer.Mol Cell Biochem. 2019 Apr;454(1-2):1-9. doi: 10.1007/s11010-018-3447-0. Epub 2018 Oct 10.
673 TNF- promotes colon cancer cell migration and invasion by upregulating TROP-2.Oncol Lett. 2018 Mar;15(3):3820-3827. doi: 10.3892/ol.2018.7735. Epub 2018 Jan 5.
674 Thymine DNA glycosylase promotes transactivation of -catenin/TCFs by cooperating with CBP.J Mol Cell Biol. 2014 Jun;6(3):231-9. doi: 10.1093/jmcb/mju014. Epub 2014 Apr 18.
675 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369.
676 TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.Nat Cell Biol. 2013 Jul;15(7):818-28. doi: 10.1038/ncb2774. Epub 2013 Jun 23.
677 Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human 4-Galactosyltransferase 4 Gene Promoters.Sensors (Basel). 2018 Aug 6;18(8):2573. doi: 10.3390/s18082573.
678 TFF3 and TFF1 expression levels are elevated in colorectal cancer and promote the malignant behavior of colon cancer by activating the EMT process.Int J Oncol. 2019 Oct;55(4):789-804. doi: 10.3892/ijo.2019.4854. Epub 2019 Aug 5.
679 Tissue Factor Pathway Inhibitor Gene Polymorphism -33TC Predicts Improved Disease-Free Survival in Colorectal Cancer.Ann Surg Oncol. 2016 Jul;23(7):2274-80. doi: 10.1245/s10434-016-5169-4. Epub 2016 Mar 11.
680 Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis.Cancer Res. 1999 Jul 15;59(14):3379-86.
681 Allele-specific expression of TGFBR1 in colon cancer patients.Carcinogenesis. 2010 Oct;31(10):1800-4. doi: 10.1093/carcin/bgq165. Epub 2010 Aug 12.
682 Loss of TGF signaling promotes colon cancer progression and tumor-associated inflammation.Oncotarget. 2017 Jan 17;8(3):3826-3839. doi: 10.18632/oncotarget.9830.
683 The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells.Cell Physiol Biochem. 2018;49(4):1539-1550. doi: 10.1159/000493457. Epub 2018 Sep 13.
684 The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.Anticancer Drugs. 2007 Apr;18(4):427-33. doi: 10.1097/CAD.0b013e328013d99e.
685 Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer.Gastroenterology. 2008 Aug;135(2):518-28. doi: 10.1053/j.gastro.2008.04.022. Epub 2008 Apr 23.
686 Toll-like receptor 6 expression, sequence variants, and their association with colorectal cancer risk.J Cancer. 2019 Jun 2;10(13):2969-2981. doi: 10.7150/jca.31011. eCollection 2019.
687 Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract.Histol Histopathol. 2004 Oct;19(4):1021-31. doi: 10.14670/HH-19.1021.
688 Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.Oncotarget. 2017 Jun 13;8(24):38351-38366. doi: 10.18632/oncotarget.16323.
689 Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts.Exp Cell Res. 2018 Jan 15;362(2):332-342. doi: 10.1016/j.yexcr.2017.11.034. Epub 2017 Nov 28.
690 Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5.J Cell Biochem. 2019 Jan;120(1):928-939. doi: 10.1002/jcb.27456. Epub 2018 Aug 30.
691 Distinct Expression Patterns of Two Tumor Necrosis Factor Superfamily Member 15 Gene Isoforms in Human Colon Cancer.Dig Dis Sci. 2019 Jul;64(7):1857-1867. doi: 10.1007/s10620-019-05507-8. Epub 2019 Feb 20.
692 Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30(-) Tumors.Mol Ther. 2019 Oct 2;27(10):1825-1835. doi: 10.1016/j.ymthe.2019.06.007. Epub 2019 Jun 19.
693 Expression of Tumor-mediated CD137 ligand in human colon cancer indicates dual signaling effects.Oncoimmunology. 2019 Sep 6;8(12):e1651622. doi: 10.1080/2162402X.2019.1651622. eCollection 2019.
694 3-Bromopyruvate potentiates TRAIL-induced apoptosis in human colon cancer cells through a reactive oxygen species- and caspase-dependent mitochondrial pathway.Can J Physiol Pharmacol. 2019 Dec;97(12):1176-1184. doi: 10.1139/cjpp-2019-0131. Epub 2019 Sep 6.
695 Enormous influence of TNIK knockdown on intracellular signals and cell survival.Hum Cell. 2011 Sep;24(3):121-6. doi: 10.1007/s13577-011-0023-2. Epub 2011 Jun 28.
696 Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway.Int J Oncol. 2016 Apr;48(4):1333-40. doi: 10.3892/ijo.2016.3360. Epub 2016 Jan 26.
697 Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin.Cancer Res. 2009 Jun 1;69(11):4563-6. doi: 10.1158/0008-5472.CAN-09-0117.
698 Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A.J Cell Biochem. 2018 Sep;119(9):7256-7263. doi: 10.1002/jcb.26916. Epub 2018 May 15.
699 Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen.PLoS One. 2014 Apr 15;9(4):e95200. doi: 10.1371/journal.pone.0095200. eCollection 2014.
700 TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer.J Transl Med. 2013 Dec 17;11:313. doi: 10.1186/1479-5876-11-313.
701 Identification of key tumorigenesisrelated genes and their microRNAs in colon cancer.Oncol Rep. 2018 Dec;40(6):3551-3560. doi: 10.3892/or.2018.6726. Epub 2018 Sep 21.
702 Ebp1 p48 promotes oncogenic activities in human colon cancer cells through regulation of TIF-90-mediated ribosomal RNA synthesis.J Cell Physiol. 2019 Aug;234(10):17612-17621. doi: 10.1002/jcp.28385. Epub 2019 Feb 22.
703 The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage.Biochem Pharmacol. 2018 Oct;156:291-301. doi: 10.1016/j.bcp.2018.08.039. Epub 2018 Aug 25.
704 MiR-133a Is Functionally Involved in Doxorubicin-Resistance in Breast Cancer Cells MCF-7 via Its Regulation of the Expression of Uncoupling Protein 2.PLoS One. 2015 Jun 24;10(6):e0129843. doi: 10.1371/journal.pone.0129843. eCollection 2015.
705 Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships. Chem Res Toxicol. 2019 Nov 18;32(11):2353-2364. doi: 10.1021/acs.chemrestox.9b00352. Epub 2019 Oct 29.
706 Downregulation of Drp1, a fission regulator, is associated with human lung and colon cancers.Acta Biochim Biophys Sin (Shanghai). 2018 Feb 1;50(2):209-215. doi: 10.1093/abbs/gmx137.
707 Urotensin-II receptor is over-expressed in colon cancer cell lines and in colon carcinoma in humans.Eur J Clin Invest. 2014;44(3):285-94. doi: 10.1111/eci.12231. Epub 2014 Jan 22.
708 KITENIN increases invasion and migration of mouse squamous cancer cells and promotes pulmonary metastasis in a mouse squamous tumor model.FEBS Lett. 2009 Feb 18;583(4):711-7. doi: 10.1016/j.febslet.2009.01.014. Epub 2009 Jan 21.
709 Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2.Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210. doi: 10.1016/j.bbrc.2018.10.050. Epub 2018 Oct 14.
710 A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatment.Aging (Albany NY). 2019 Oct 9;11(19):8587-8603. doi: 10.18632/aging.102349. Epub 2019 Oct 9.
711 Long Noncoding RNA ASLNC07322 Functions in VEGF-C Expression Regulated by Smad4 during Colon Cancer Metastasis.Mol Ther Nucleic Acids. 2019 Dec 6;18:851-862. doi: 10.1016/j.omtn.2019.10.012. Epub 2019 Oct 18.
712 VPAC1 overexpression is associated with poor differentiation in colon cancer.Tumour Biol. 2014 Jul;35(7):6397-404. doi: 10.1007/s13277-014-1852-x. Epub 2014 Mar 28.
713 Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.Cancer Immunol Res. 2019 Jul;7(7):1079-1090. doi: 10.1158/2326-6066.CIR-18-0507. Epub 2019 May 14.
714 Colitis and colon cancer in WASP-deficient mice require helicobacter species.Inflamm Bowel Dis. 2013 Sep;19(10):2041-50. doi: 10.1097/MIB.0b013e318295fd8f.
715 WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.BMC Cancer. 2018 Jun 20;18(1):673. doi: 10.1186/s12885-018-4580-6.
716 Wee1 inhibition can suppress tumor proliferation and sensitize p53 mutant colonic cancer cells to the anticancer effect of irinotecan.Mol Med Rep. 2018 Feb;17(2):3344-3349. doi: 10.3892/mmr.2017.8230. Epub 2017 Dec 8.
717 The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer.Anticancer Res. 2019 Apr;39(4):1719-1728. doi: 10.21873/anticanres.13278.
718 Investigation of Insulin-Like Growth Factor-1 (IGF-1), P53, and Wilms' Tumor 1 (WT1) Expression Levels in the Colon Polyp Subtypes in Colon Cancer.Med Sci Monit. 2019 Jul 25;25:5510-5517. doi: 10.12659/MSM.915335.
719 Suppression of YAP by DDP disrupts colon tumor progression.Oncol Rep. 2018 May;39(5):2114-2126. doi: 10.3892/or.2018.6297. Epub 2018 Mar 6.
720 Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis.Clin Cancer Res. 2014 Feb 15;20(4):837-46. doi: 10.1158/1078-0432.CCR-13-1854. Epub 2013 Dec 9.
721 MiR-3653 inhibits the metastasis and epithelial-mesenchymal transition of colon cancer by targeting Zeb2.Pathol Res Pract. 2019 Oct;215(10):152577. doi: 10.1016/j.prp.2019.152577. Epub 2019 Aug 2.
722 The candidate oncogene ZNF217 is frequently amplified in colon cancer.J Pathol. 2004 Nov;204(3):282-8. doi: 10.1002/path.1632.
723 Targeting CCR8 Induces Protective Antitumor Immunity and Enhances Vaccine-Induced Responses in Colon Cancer.Cancer Res. 2018 Sep 15;78(18):5340-5348. doi: 10.1158/0008-5472.CAN-18-1119. Epub 2018 Jul 19.
724 Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.Clin Exp Metastasis. 2010 May;27(5):307-18. doi: 10.1007/s10585-010-9328-x. Epub 2010 Apr 7.
725 Expression of cellular apoptosis susceptibility (CAS) in the human testis and testicular germ cell tumors.Med Oncol. 2019 May 29;36(7):61. doi: 10.1007/s12032-019-1281-1.
726 Increased diacylglycerol kinase expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.BMC Cancer. 2014 Mar 19;14:208. doi: 10.1186/1471-2407-14-208.
727 Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer.Int J Oncol. 2012 Mar;40(3):889-98. doi: 10.3892/ijo.2011.1245. Epub 2011 Oct 25.
728 Overexpression of GRK3, Promoting Tumor Proliferation, Is Predictive of Poor Prognosis in Colon Cancer.Dis Markers. 2017;2017:1202710. doi: 10.1155/2017/1202710. Epub 2017 Dec 28.
729 Tumor-suppressive function and mechanism of HOXB13 in right-sided colon cancer.Signal Transduct Target Ther. 2019 Nov 29;4:51. doi: 10.1038/s41392-019-0086-1. eCollection 2019.
730 Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon--Dependent Manner.Cancer Immunol Res. 2018 Apr;6(4):409-421. doi: 10.1158/2326-6066.CIR-17-0218. Epub 2018 Feb 20.
731 TAK-ing aim at chemoresistance: The emerging role of MAP3K7 as a target for cancer therapy.Drug Resist Updat. 2017 Nov;33-35:36-42. doi: 10.1016/j.drup.2017.10.004. Epub 2017 Nov 3.
732 Novel, isoform-selective, cholecystokinin A receptor antagonist inhibits colon and pancreatic cancers in preclinical models through novel mechanism of action.Oncol Rep. 2016 Apr;35(4):2097-106. doi: 10.3892/or.2016.4588. Epub 2016 Jan 22.
733 Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.PLoS One. 2012;7(5):e37312. doi: 10.1371/journal.pone.0037312. Epub 2012 May 17.
734 MicroRNA-185 suppresses growth and invasion of colon cancer cells through inhibition of the hypoxiainducible factor-2 pathway in vitro and in vivo.Mol Med Rep. 2014 Nov;10(5):2401-8. doi: 10.3892/mmr.2014.2562. Epub 2014 Sep 12.
735 High Expression of PLOD1 Drives Tumorigenesis and Affects Clinical Outcome in Gastrointestinal Carcinoma.Genet Test Mol Biomarkers. 2018 Jun;22(6):366-373. doi: 10.1089/gtmb.2018.0009. Epub 2018 May 3.
736 Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.J Cancer Res Clin Oncol. 2010 Feb;136(2):249-59. doi: 10.1007/s00432-009-0656-7. Epub 2009 Aug 12.
737 Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers.Clin Transl Med. 2014 Nov 18;3:37. doi: 10.1186/s40169-014-0037-y. eCollection 2014.
738 Thymosin 4 in colorectal cancer is localized predominantly at the invasion front in tumor cells undergoing epithelial mesenchymal transition.Cancer Biol Ther. 2012 Feb 15;13(4):191-7. doi: 10.4161/cbt.13.4.18691. Epub 2012 Feb 15.
739 The haplotypes of TNFRSF17 polymorphisms are associated with colon cancer in a Korean population.Int J Colorectal Dis. 2012 Jun;27(6):701-7. doi: 10.1007/s00384-011-1364-8. Epub 2011 Nov 24.
740 Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit.Theranostics. 2019 Apr 13;9(9):2526-2540. doi: 10.7150/thno.32915. eCollection 2019.
741 MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5. Mol Med Rep. 2015 Sep;12(3):3930-3936.
742 Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer. Cancer Res. 2007 May 15;67(10):4860-8. doi: 10.1158/0008-5472.CAN-06-3096.
743 Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB(0,+) to deliver chemotherapeutic agents for colon cancer therapy.Drug Deliv. 2017 Nov;24(1):1338-1349. doi: 10.1080/10717544.2017.1377316.
744 Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi.Int J Cancer. 2008 May 1;122(9):1999-2007. doi: 10.1002/ijc.23321.
745 Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon cancer in order to inhibit liver metastasis in nude mice.Tumour Biol. 2015 Aug;36(8):6011-8. doi: 10.1007/s13277-015-3277-6. Epub 2015 Mar 5.
746 Epigenetic silencing of the sulfate transporter gene DTDST induces sialyl Lewisx expression and accelerates proliferation of colon cancer cells. Cancer Res. 2010 May 15;70(10):4064-73.
747 The Constituents of the Stems of Cissus assamica and Their Bioactivities.Molecules. 2018 Oct 28;23(11):2799. doi: 10.3390/molecules23112799.
748 Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4 Is Mediated by a Novel Composite Regulatory Element.Mol Pharmacol. 2018 May;93(5):541-552. doi: 10.1124/mol.117.110619. Epub 2018 Mar 8.
749 Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2, and P-ERK.J Mol Med (Berl). 2012 Jun;90(6):707-18. doi: 10.1007/s00109-011-0851-2. Epub 2012 Jan 7.
750 Glutathione, an Antioxidant Tripeptide: Dual Roles in Carcinogenesis and Chemoprevention.Curr Protein Pept Sci. 2019;20(9):907-917. doi: 10.2174/1389203720666190206130003.
751 Adenine Inhibits the Growth of Colon Cancer Cells via AMP-Activated Protein Kinase Mediated Autophagy.Evid Based Complement Alternat Med. 2019 Sep 12;2019:9151070. doi: 10.1155/2019/9151070. eCollection 2019.
752 Polymorphisms in the carcinogen detoxification genes CYB5A and CYB5R3 and breast cancer risk in African American women.Cancer Causes Control. 2014 Nov;25(11):1513-21. doi: 10.1007/s10552-014-0454-7. Epub 2014 Sep 16.
753 CD133 expression predicts post-operative recurrence in patients with colon cancer with peritoneal metastasis.Int J Oncol. 2018 Mar;52(3):721-732. doi: 10.3892/ijo.2018.4240. Epub 2018 Jan 8.
754 N-acetyl transferase 2/environmental factors and their association as a modulating risk factor for sporadic colon and rectal cancer.J Clin Lab Anal. 2017 Sep;31(5):e22098. doi: 10.1002/jcla.22098. Epub 2016 Nov 24.
755 Association of Survival With Adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors After Colon Cancer Diagnosis: The CALGB 89803/Alliance Trial.JAMA Oncol. 2018 Jun 1;4(6):783-790. doi: 10.1001/jamaoncol.2018.0126.
756 Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15?cells. Food Chem Toxicol. 2018 Jun;116(Pt B):315-322. doi: 10.1016/j.fct.2018.04.053. Epub 2018 Apr 24.
757 Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo--linolenic acid for colon cancer suppression.Redox Biol. 2019 Feb;21:101085. doi: 10.1016/j.redox.2018.101085. Epub 2018 Dec 18.
758 Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.Carcinogenesis. 2018 Mar 8;39(3):375-388. doi: 10.1093/carcin/bgy011.
759 AKR1B10, a transcriptional target of p53, is downregulated in colorectal cancers associated with poor prognosis.Mol Cancer Res. 2013 Dec;11(12):1554-63. doi: 10.1158/1541-7786.MCR-13-0330-T. Epub 2013 Oct 18.
760 Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.Chem Biol Interact. 2015 Jun 5;234:38-44. doi: 10.1016/j.cbi.2014.12.038. Epub 2015 Jan 29.
761 Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells.Genes Chromosomes Cancer. 2008 Feb;47(2):95-106. doi: 10.1002/gcc.20511.
762 Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.Br J Cancer. 2005 Mar 14;92(5):882-7. doi: 10.1038/sj.bjc.6602362.
763 Genetic modification of the effect of alcohol consumption on CHD.Proc Nutr Soc. 2004 Feb;63(1):73-9. doi: 10.1079/PNS2003321.
764 Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk.Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2540-8. doi: 10.1158/1055-9965.EPI-09-0228. Epub 2009 Aug 25.
765 Association of common gene variants in vitamin D modulating genes and colon cancer recurrence.J Cancer Res Clin Oncol. 2013 Sep;139(9):1457-64. doi: 10.1007/s00432-013-1461-x. Epub 2013 Jun 23.
766 Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk.Clin Chem. 1995 Dec;41(12 Pt 2):1864-9.
767 Genetic polymorphism of cholesterol 7alpha-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.Cancer Sci. 2006 May;97(5):406-10. doi: 10.1111/j.1349-7006.2006.00182.x.
768 MicroRNA-17 induces epithelial-mesenchymal transition consistent with the cancer stem cell phenotype by regulating CYP7B1 expression in colon cancer. Int J Mol Med. 2016 Aug;38(2):499-506.
769 Synthetic lethality by lentiviral short hairpin RNA silencing of thymidylate kinase and doxorubicin in colon cancer cells regardless of the p53 status. Cancer Res. 2008 Apr 15;68(8):2831-40. doi: 10.1158/0008-5472.CAN-07-3069.
770 Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner.J Biol Chem. 2019 Jun 21;294(25):9949-9958. doi: 10.1074/jbc.RA118.007181. Epub 2019 May 15.
771 Overexpression of flavin-containing monooxygenase 5 predicts poor prognosis in patients with colorectal cancer.Oncol Lett. 2018 Mar;15(3):3923-3927. doi: 10.3892/ol.2018.7724. Epub 2018 Jan 4.
772 Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients.Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):6012-9.
773 Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth.Cell Chem Biol. 2019 Sep 19;26(9):1214-1228.e25. doi: 10.1016/j.chembiol.2019.06.005. Epub 2019 Jul 11.
774 Mutation of GDP-mannose-4,6-dehydratase in colorectal cancer metastasis.PLoS One. 2013 Jul 29;8(7):e70298. doi: 10.1371/journal.pone.0070298. Print 2013.
775 The diagnostic potential of glutathione S-transferase (GST) polymorphisms in patients with colorectal cancer.Adv Clin Exp Med. 2018 Nov;27(11):1561-1566. doi: 10.17219/acem/74682.
776 15-Keto prostaglandin E(2) induces heme oxygenase-1 expression through activation of Nrf2 in human colon epithelial CCD 841 CoN cells.Arch Biochem Biophys. 2020 Jan 15;679:108162. doi: 10.1016/j.abb.2019.108162. Epub 2019 Dec 24.
777 Effect of exogenous MSH6 and POLD1 expression on the mutation rate of the HPRT locus in a human colon cancer cell line with mutator phenotype, DLD-1.Int J Oncol. 2004 Mar;24(3):697-702.
778 17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer.J Steroid Biochem Mol Biol. 2003 Nov;87(2-3):133-40. doi: 10.1016/j.jsbmb.2003.08.008.
779 The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.Nat Commun. 2016 Mar 7;7:10764. doi: 10.1038/ncomms10764.
780 Downregulation of metallothionein 1F, a putative oncosuppressor, by loss of heterozygosity in colon cancer tissue.Biochim Biophys Acta. 2012 Jun;1822(6):918-26. doi: 10.1016/j.bbadis.2012.02.021. Epub 2012 Mar 9.
781 Integrating proteomic and transcriptomic high-throughput surveys for search of new biomarkers of colon tumors.Funct Integr Genomics. 2011 Jun;11(2):215-24. doi: 10.1007/s10142-010-0200-5. Epub 2010 Nov 9.
782 Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.Mol Nutr Food Res. 2013 Apr;57(4):721-34. doi: 10.1002/mnfr.201200180. Epub 2012 Sep 7.
783 Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake.Anticancer Res. 2011 Jun;31(6):2135-9.
784 DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1 expression through the PI3K-AKT pathway.Cancer Manag Res. 2018 Oct 16;10:4615-4629. doi: 10.2147/CMAR.S172008. eCollection 2018.
785 Three-dimensional computed tomographic angiography with computed tomographic colonography for laparoscopic colorectal surgery.Jpn J Radiol. 2018 Dec;36(12):698-705. doi: 10.1007/s11604-018-0775-7. Epub 2018 Sep 14.
786 Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer.Mol Carcinog. 2009 Jul;48(7):642-7. doi: 10.1002/mc.20510.
787 Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species.Cancer Res. 2001 Mar 1;61(5):1810-5.
788 A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells.Arch Biochem Biophys. 2014 Jan 1;541:21-9. doi: 10.1016/j.abb.2013.10.023. Epub 2013 Nov 12.
789 Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer.Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1626-32. doi: 10.1158/1055-9965.EPI-04-0682.
790 The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk.Cancer. 2013 Jul 1;119(13):2477-85. doi: 10.1002/cncr.28009. Epub 2013 Apr 10.
791 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability.PLoS One. 2018 Mar 8;13(3):e0193560. doi: 10.1371/journal.pone.0193560. eCollection 2018.
792 ACTL6A expression promotes invasion, metastasis and epithelial mesenchymal transition of colon cancer.BMC Cancer. 2018 Oct 22;18(1):1020. doi: 10.1186/s12885-018-4931-3.
793 Aberrant Epigenetic Modifications of LPHN2 Function as a Potential Cisplatin-Specific Biomarker for Human Gastrointestinal Cancer.Cancer Res Treat. 2016 Apr;48(2):676-86. doi: 10.4143/crt.2015.153. Epub 2015 Sep 22.
794 Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling.Pathol Res Pract. 2019 May;215(5):1012-1019. doi: 10.1016/j.prp.2019.02.008. Epub 2019 Feb 27.
795 Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex.Cancer Sci. 2019 Dec;110(12):3788-3801. doi: 10.1111/cas.14205. Epub 2019 Nov 15.
796 miR-3120-5p promotes colon cancer stem cell stemness and invasiveness through targeting Axin2.Biochem Biophys Res Commun. 2018 Feb 5;496(2):302-308. doi: 10.1016/j.bbrc.2018.01.021. Epub 2018 Jan 4.
797 Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation.Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3210-3220. doi: 10.1016/j.bbagen.2016.08.005. Epub 2016 Aug 14.
798 Suppression of B3GNT7 gene expression in colon adenocarcinoma and its potential effect in the metastasis of colon cancer cells.Glycobiology. 2014 Apr;24(4):359-67. doi: 10.1093/glycob/cwu002. Epub 2014 Jan 12.
799 Clinical and molecular characterization of individuals with recurrent genomic disorder at 10q22.3q23.2.Clin Genet. 2010 Aug;78(2):162-8. doi: 10.1111/j.1399-0004.2010.01373.x. Epub 2010 Feb 9.
800 Carbonic anhydrase-related protein VIII promotes colon cancer cell growth.Mol Carcinog. 2007 Mar;46(3):208-14. doi: 10.1002/mc.20264.
801 Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.J Surg Oncol. 2017 Nov;116(6):706-715. doi: 10.1002/jso.24705. Epub 2017 Jun 1.
802 Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells.Biochem Biophys Res Commun. 2013 May 17;434(4):898-903. doi: 10.1016/j.bbrc.2013.04.053. Epub 2013 Apr 23.
803 Elevated expression of C10orf3 (chromosome 10 open reading frame 3) is involved in the growth of human colon tumor.Oncogene. 2006 Jan 19;25(3):480-6. doi: 10.1038/sj.onc.1209051.
804 Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer.Clin Cancer Res. 2011 Jul 1;17(13):4531-40. doi: 10.1158/1078-0432.CCR-10-0763. Epub 2011 May 6.
805 Ingested nitrate, disinfection by-products, and risk of colon and rectal cancers in the Iowa Women's Health Study cohort.Environ Int. 2019 May;126:242-251. doi: 10.1016/j.envint.2019.02.010. Epub 2019 Feb 26.
806 TERT's role in colorectal carcinogenesis.Mol Carcinog. 2013 Jul;52(7):507-13. doi: 10.1002/mc.21885. Epub 2012 Feb 21.
807 The protein secretion modulator TMED9 drives CNIH4/TGF/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases.Oncogene. 2019 Jul;38(29):5817-5837. doi: 10.1038/s41388-019-0845-z. Epub 2019 Jun 28.
808 SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin.Nat Commun. 2016 Jun 29;7:11996. doi: 10.1038/ncomms11996.
809 Silencing of bidirectional promoters by DNA methylation in tumorigenesis.Cancer Res. 2006 May 15;66(10):5077-84. doi: 10.1158/0008-5472.CAN-05-2629.
810 Cortactin promotes colon cancer progression by regulating ERK pathway.Int J Oncol. 2015 Sep;47(3):1034-42. doi: 10.3892/ijo.2015.3072. Epub 2015 Jul 6.
811 Expression of CUEDC2 in colorectal cancer with different invasion and migration abilities.J Int Med Res. 2019 Feb;47(2):905-914. doi: 10.1177/0300060518813072. Epub 2019 Jan 17.
812 Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers.APMIS. 2009 Dec;117(12):880-5. doi: 10.1111/j.1600-0463.2009.02550.x.
813 Lymph node CXCL17 messenger RNA: A new prognostic biomarker for colon cancer.Tumour Biol. 2018 Sep;40(9):1010428318799251. doi: 10.1177/1010428318799251.
814 Diagnostic and prognostic values of CXC motif chemokine ligand 3 in patients with colon cancer.Oncol Rep. 2019 Nov;42(5):1996-2008. doi: 10.3892/or.2019.7326. Epub 2019 Sep 19.
815 Expression of DDB2 Protein in the Initiation, Progression, and Prognosis of Colorectal Cancer.Dig Dis Sci. 2018 Nov;63(11):2959-2968. doi: 10.1007/s10620-018-5224-z. Epub 2018 Jul 27.
816 Loperamide overcomes the resistance of colon cancer cells to bortezomib by inducing CHOP-mediated paraptosis-like cell death.Biochem Pharmacol. 2019 Apr;162:41-54. doi: 10.1016/j.bcp.2018.12.006. Epub 2018 Dec 7.
817 Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion.Oncotarget. 2015 Jul 30;6(21):18577-89. doi: 10.18632/oncotarget.4094.
818 Tumor suppressor DLC-1 induces apoptosis and inhibits the growth and invasion of colon cancer cells through the Wnt/-catenin signaling pathway.Oncol Rep. 2014 May;31(5):2270-8. doi: 10.3892/or.2014.3057. Epub 2014 Mar 5.
819 Eukaryotic translation initiation factor 3 subunit G promotes human colorectal cancer.Am J Transl Res. 2019 Feb 15;11(2):612-623. eCollection 2019.
820 GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1.Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):5951-9. doi: 10.1158/1078-0432.CCR-06-0736.
821 A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines.Am J Pathol. 1993 Feb;142(2):425-31.
822 Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress.Int J Cancer. 2017 Jun 15;140(12):2734-2747. doi: 10.1002/ijc.30698. Epub 2017 Apr 3.
823 Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.Biomed Res Int. 2015;2015:853573. doi: 10.1155/2015/853573. Epub 2015 Nov 23.
824 Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer.Cancer Res. 2006 Jan 15;66(2):763-9. doi: 10.1158/0008-5472.CAN-05-3771.
825 Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal adenocarcinoma.Front Med. 2020 Feb;14(1):91-100. doi: 10.1007/s11684-019-0696-6. Epub 2019 Aug 2.
826 Expression of IARS2 gene in colon cancer and effect of its knockdown on biological behavior of RKO cells.Int J Clin Exp Pathol. 2015 Oct 1;8(10):12151-9. eCollection 2015.
827 Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy.J Exp Clin Cancer Res. 2019 Feb 8;38(1):63. doi: 10.1186/s13046-019-1072-8.
828 Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.Biosci Rep. 2017 Feb 10;37(1):BSR20160432. doi: 10.1042/BSR20160432. Print 2017 Feb 28.
829 Loss of KLF14 triggers centrosome amplification and tumorigenesis.Nat Commun. 2015 Oct 6;6:8450. doi: 10.1038/ncomms9450.
830 Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation.Cell Commun Signal. 2019 Oct 17;17(1):129. doi: 10.1186/s12964-019-0444-1.
831 High expression of leucinerich repeatcontaining8A is indicative of a worse outcome of colon cancer patients by enhancing cancer cell growth and metastasis.Oncol Rep. 2018 Sep;40(3):1275-1286. doi: 10.3892/or.2018.6556. Epub 2018 Jul 10.
832 Overexpression of lumican affects the migration of human colon cancer cells through up-regulation of gelsolin and filamentous actin reorganization.Exp Cell Res. 2012 Nov 1;318(18):2312-23. doi: 10.1016/j.yexcr.2012.07.005. Epub 2012 Jul 16.
833 A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer.Oncol Lett. 2018 Nov;16(5):6652-6662. doi: 10.3892/ol.2018.9487. Epub 2018 Sep 24.
834 Effect of RTKN on progression and metastasis of colon cancer in vitro.Biomed Pharmacother. 2015 Aug;74:117-23. doi: 10.1016/j.biopha.2015.07.012. Epub 2015 Aug 8.
835 Promoter switch: a novel mechanism causing biallelic PEG1/MEST expression in invasive breast cancer.Hum Mol Genet. 2002 Jun 1;11(12):1449-53. doi: 10.1093/hmg/11.12.1449.
836 FAM188B enhances cell survival via interaction with USP7.Cell Death Dis. 2018 May 24;9(6):633. doi: 10.1038/s41419-018-0650-6.
837 Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer.Int J Oncol. 2007 Aug;31(2):333-8.
838 Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.Curr Mol Med. 2016;16(9):829-839. doi: 10.2174/1566524016666161124103020.
839 MYEOV (myeloma overexpressed gene) drives colon cancer cell migration and is regulated by PGE2.J Exp Clin Cancer Res. 2010 Jun 22;29(1):81. doi: 10.1186/1756-9966-29-81.
840 NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression.Cell Death Dis. 2019 Mar 11;10(3):236. doi: 10.1038/s41419-019-1487-3.
841 Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.Oncogene. 2002 Sep 12;21(41):6387-94. doi: 10.1038/sj.onc.1205751.
842 NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor.Cell Rep. 2019 Nov 5;29(6):1469-1481.e9. doi: 10.1016/j.celrep.2019.09.087.
843 The oncogenic role of NKAP in the growth and invasion of colon cancer cells.Oncol Rep. 2019 Nov;42(5):2130-2138. doi: 10.3892/or.2019.7322. Epub 2019 Sep 18.
844 The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells.Cancer Lett. 2011 Oct 28;309(2):137-44. doi: 10.1016/j.canlet.2011.05.025. Epub 2011 Jun 22.
845 Oxytocin and oxytocin-analogue F314 inhibit cell proliferation and tumor growth of rat and mouse mammary carcinomas.Int J Cancer. 1996 Jun 11;66(6):817-20. doi: 10.1002/(SICI)1097-0215(19960611)66:6<817::AID-IJC18>3.0.CO;2-#.
846 Expression of prostaglandin H synthase-2 in human brain tumors.Acta Neuropathol. 2001 Aug;102(2):181-7. doi: 10.1007/s004010100373.
847 RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.Cancer Res. 2007 Mar 1;67(5):1997-2005. doi: 10.1158/0008-5472.CAN-06-3093.
848 PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.Cell Death Dis. 2018 Feb 15;9(3):271. doi: 10.1038/s41419-018-0320-8.
849 PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage.Cell Signal. 2013 Jan;25(1):74-84. doi: 10.1016/j.cellsig.2012.09.009. Epub 2012 Sep 11.
850 Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L.Cancer Biol Ther. 2008 Feb;7(2):285-92. doi: 10.4161/cbt.7.2.5302. Epub 2007 Nov 14.
851 siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway.Cancer Manag Res. 2019 Jun 28;11:5799-5811. doi: 10.2147/CMAR.S193805. eCollection 2019.
852 Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.Carcinogenesis. 2010 Sep;31(9):1604-11. doi: 10.1093/carcin/bgq142. Epub 2010 Jul 9.
853 A colon cancer-derived mutant of Krppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3 (GSK3) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7 (FBW7).J Biol Chem. 2014 Feb 28;289(9):5997-6005. doi: 10.1074/jbc.M113.508549. Epub 2014 Jan 7.
854 Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer.J Appl Genet. 2015 May;56(2):185-92. doi: 10.1007/s13353-014-0253-6. Epub 2014 Nov 1.
855 G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response.Radiother Oncol. 2017 Sep;124(3):395-402. doi: 10.1016/j.radonc.2017.03.002. Epub 2017 Mar 25.
856 PTPH1 immunohistochemical expression and promoter methylation in breast cancer patients from India: A retrospective study.J Cell Physiol. 2019 Feb;234(2):1071-1079. doi: 10.1002/jcp.27211. Epub 2018 Sep 6.
857 A siRNA-based method for efficient silencing of PYROXD1 gene expression in the colon cancer cell line HCT116.J Cell Biochem. 2019 Dec;120(12):19310-19317. doi: 10.1002/jcb.26858. Epub 2019 Sep 10.
858 RAB32 hypermethylation and microsatellite instability in gastric and endometrial adenocarcinomas.Int J Cancer. 2006 Aug 15;119(4):801-6. doi: 10.1002/ijc.21912.
859 A role for RAD54B in homologous recombination in human cells.EMBO J. 2002 Jan 15;21(1-2):175-80. doi: 10.1093/emboj/21.1.175.
860 Retinoblastoma binding protein 4 up-regulation is correlated with hepatic metastasis and poor prognosis in colon cancer patients.Hepatobiliary Pancreat Dis Int. 2019 Oct;18(5):446-451. doi: 10.1016/j.hbpd.2019.08.006. Epub 2019 Aug 24.
861 High RNA-binding Motif Protein 3 Expression Is Associated with Improved Clinical Outcomes in Invasive Breast Cancer.J Breast Cancer. 2018 Sep;21(3):288-296. doi: 10.4048/jbc.2018.21.e34. Epub 2018 Aug 28.
862 Blood transcriptional and microRNA responses to short-term exposure to disinfection by-products in a swimming pool.Environ Int. 2018 Jan;110:42-50. doi: 10.1016/j.envint.2017.10.003. Epub 2017 Nov 6.
863 R-spondin 2 promotes proliferation and migration via the Wnt/-catenin pathway in human hepatocellular carcinoma.Oncol Lett. 2017 Aug;14(2):1757-1765. doi: 10.3892/ol.2017.6339. Epub 2017 Jun 7.
864 SASH1 regulates proliferation, apoptosis, and invasion of osteosarcoma cell.Mol Cell Biochem. 2013 Jan;373(1-2):201-10. doi: 10.1007/s11010-012-1491-8. Epub 2012 Oct 29.
865 SR-A1, a member of the human pre-mRNA splicing factor family, and its expression in colon cancer progression.Biol Chem. 2004 Sep;385(9):785-90. doi: 10.1515/BC.2004.102.
866 Platelet-derived endothelial cell growth factor mediates Rho-associated coiled-coil domain kinase messenger RNA expression and promotes cell motility.Ann Surg Oncol. 2003 Jun;10(5):582-7. doi: 10.1245/aso.2003.08.020.
867 p34 (SEI-1) inhibits ROS-induced cell death through suppression of ASK1.Cancer Biol Ther. 2011 Sep 1;12(5):421-6. doi: 10.4161/cbt.12.5.15972. Epub 2011 Sep 1.
868 Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence.PLoS One. 2018 Feb 20;13(2):e0192958. doi: 10.1371/journal.pone.0192958. eCollection 2018.
869 Association and diagnostic value of serum SPINK4 in colorectal cancer.PeerJ. 2019 Apr 4;7:e6679. doi: 10.7717/peerj.6679. eCollection 2019.
870 Serum response factor is alternatively spliced in human colon cancer.J Surg Res. 2004 Sep;121(1):92-100. doi: 10.1016/j.jss.2004.02.031.
871 RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis.Stem Cell Reports. 2017 Aug 8;9(2):438-450. doi: 10.1016/j.stemcr.2017.06.002. Epub 2017 Jul 6.
872 Identification of new binding proteins of focal adhesion kinase using immunoprecipitation and mass spectrometry.Sci Rep. 2019 Sep 9;9(1):12908. doi: 10.1038/s41598-019-49145-6.
873 p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance.Oncogene. 2019 Mar;38(11):1905-1919. doi: 10.1038/s41388-018-0524-5. Epub 2018 Nov 2.
874 Association between interleukin-4R and TGF-1 gene polymorphisms and the risk of colorectal cancer in a Korean population.Colorectal Dis. 2010 Dec;12(12):1208-12. doi: 10.1111/j.1463-1318.2009.02080.x.
875 Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers.Oncotarget. 2016 Jun 21;7(25):38143-38153. doi: 10.18632/oncotarget.9411.
876 NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.Oncotarget. 2016 Feb 16;7(7):8399-412. doi: 10.18632/oncotarget.6724.
877 Serum Levels of TRIM72 Are Lower among Patients with Colon Cancer: Identification of a Potential Diagnostic Marker.Tohoku J Exp Med. 2018 May;245(1):61-68. doi: 10.1620/tjem.245.61.
878 The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.Cancer Res. 2018 Aug 15;78(16):4533-4548. doi: 10.1158/0008-5472.CAN-17-3149. Epub 2018 Jun 18.
879 Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types.PLoS Genet. 2013 Apr;9(4):e1003464. doi: 10.1371/journal.pgen.1003464. Epub 2013 Apr 25.
880 SRSF1 Prevents DNA Damage and Promotes Tumorigenesis through Regulation of DBF4B Pre-mRNA Splicing.Cell Rep. 2017 Dec 19;21(12):3406-3413. doi: 10.1016/j.celrep.2017.11.091.
881 A recombinant reporter system for monitoring reactivation of an endogenously DNA hypermethylated gene.Cancer Res. 2014 Jul 15;74(14):3834-43. doi: 10.1158/0008-5472.CAN-13-2287. Epub 2014 May 29.
882 Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells.Sci Rep. 2019 Jan 30;9(1):950. doi: 10.1038/s41598-018-37521-7.
883 DAC can restore expression of NALP1 to suppress tumor growth in colon cancer.Cell Death Dis. 2015 Jan 22;6(1):e1602. doi: 10.1038/cddis.2014.532.
884 Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas.Gastroenterology. 2006 Nov;131(5):1418-30. doi: 10.1053/j.gastro.2006.08.034. Epub 2006 Aug 18.
885 Disruption of Core 1-mediated O-glycosylation oppositely regulates CD44 expression in human colon cancer cells and tumor-derived exosomes.Biochem Biophys Res Commun. 2020 Jan 8;521(2):514-520. doi: 10.1016/j.bbrc.2019.10.149. Epub 2019 Oct 31.
886 DBC1 regulates Wnt/-catenin-mediated expression of MACC1, a key regulator of cancer progression, in colon cancer.Cell Death Dis. 2018 Aug 6;9(8):831. doi: 10.1038/s41419-018-0899-9.
887 Basic transcription factor 3 expression silencing attenuates colon cancer cell proliferation and migration in vitro.Oncol Lett. 2019 Jan;17(1):113-118. doi: 10.3892/ol.2018.9613. Epub 2018 Oct 24.
888 Surgical trauma-induced CCL18 promotes recruitment of regulatory T cells and colon cancer progression.J Cell Physiol. 2019 Apr;234(4):4608-4616. doi: 10.1002/jcp.27245. Epub 2018 Sep 14.
889 Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.Bioorg Chem. 2019 Dec;93:103317. doi: 10.1016/j.bioorg.2019.103317. Epub 2019 Sep 26.
890 ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer.Mol Oncol. 2018 Oct;12(10):1706-1717. doi: 10.1002/1878-0261.12365. Epub 2018 Aug 20.
891 Downregulation of DBN1 is related to vincristine resistance in colon cancer cells.J Cancer Res Ther. 2019 Jan-Mar;15(1):38-41. doi: 10.4103/0973-1482.192766.
892 Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling.Sci Rep. 2019 Jul 31;9(1):11094. doi: 10.1038/s41598-019-47539-0.
893 Use of the tumor repressor DEDD as a prognostic marker of cancer metastasis.Methods Mol Biol. 2014;1165:197-222. doi: 10.1007/978-1-4939-0856-1_14.
894 Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance.J Cancer. 2017 Jul 21;8(12):2336-2345. doi: 10.7150/jca.19411. eCollection 2017.
895 Forkhead box O3 promotes colon cancer proliferation and drug resistance by activating MDR1 expression.Mol Genet Genomic Med. 2019 Mar;7(3):e554. doi: 10.1002/mgg3.554. Epub 2019 Jan 8.
896 Independent prognostic genes and mechanism investigation for colon cancer.Biol Res. 2018 Apr 13;51(1):10. doi: 10.1186/s40659-018-0158-7.
897 Plasma Histone H4 and H4K20 Trimethylation Levels Differ Between Colon Cancer and Precancerous Polyps.In Vivo. 2019 Sep-Oct;33(5):1653-1658. doi: 10.21873/invivo.11651.
898 HBP1 promoter methylation augments the oncogenic -catenin to correlate with prognosis in NSCLC.J Cell Mol Med. 2014 Sep;18(9):1752-61. doi: 10.1111/jcmm.12318. Epub 2014 Jun 4.
899 HCP5 promotes colon cancer development by activating AP1G1 via PI3K/AKT pathway.Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):2786-2793. doi: 10.26355/eurrev_201904_17553.
900 LncRNA-UCA1 modulates progression of colon cancer through regulating the miR-28-5p/HOXB3 axis.J Cell Biochem. 2019 May;120(5):6926-6936. doi: 10.1002/jcb.27630. Epub 2019 Jan 16.
901 Candidate genes involved in metastasis of colon cancer identified by integrated analysis.Cancer Med. 2019 May;8(5):2338-2347. doi: 10.1002/cam4.2071. Epub 2019 Mar 18.
902 miR-1307-3p overexpression inhibits cell proliferation and promotes cell apoptosis by targeting ISM1 in colon cancer.Mol Cell Probes. 2019 Dec;48:101445. doi: 10.1016/j.mcp.2019.101445. Epub 2019 Sep 9.
903 ITGB4 is a novel prognostic factor in colon cancer.J Cancer. 2019 Aug 28;10(21):5223-5233. doi: 10.7150/jca.29269. eCollection 2019.
904 Livin promotes colon cancer progression by regulation of H2A.X(Y39ph) via JMJD6.Life Sci. 2019 Oct 1;234:116788. doi: 10.1016/j.lfs.2019.116788. Epub 2019 Aug 22.
905 MALAT1-miR663a negative feedback loop in colon cancer cell functions through direct miRNA-lncRNA binding.Cell Death Dis. 2018 Aug 28;9(9):857. doi: 10.1038/s41419-018-0925-y.
906 CBP-triggered KDM2B acetylation accelerates the carcinogenesis of colon cancer.J Cell Physiol. 2020 Mar;235(3):2901-2910. doi: 10.1002/jcp.29196. Epub 2019 Sep 17.
907 Lemur tyrosine kinase 2 acts as a positive regulator of NF-B activation and colon cancer cell proliferation.Cancer Lett. 2019 Jul 10;454:70-77. doi: 10.1016/j.canlet.2019.04.011. Epub 2019 Apr 10.
908 LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL? and TNF?"Xu J. Zhang W
909 MKK6 is upregulated in human esophageal, stomach, and colon cancers.Cancer Invest. 2014 Oct;32(8):416-22. doi: 10.3109/07357907.2014.933236. Epub 2014 Jul 14.
910 Factors Affecting Adherence in a Pragmatic Trial of Annual Fecal Immunochemical Testing for Colorectal Cancer.J Gen Intern Med. 2019 Jun;34(6):978-985. doi: 10.1007/s11606-018-4820-0. Epub 2019 Jan 25.
911 Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells. Nutr Cancer. 2011;63(7):1133-42. doi: 10.1080/01635581.2011.605984. Epub 2011 Sep 15.
912 Promoter hypomethylation contributes to the expression of MUC3A in cancer cells.Biochem Biophys Res Commun. 2010 Jun 25;397(2):333-9. doi: 10.1016/j.bbrc.2010.05.124. Epub 2010 May 27.
913 Long non-coding RNA MBNL1-AS1 regulates proliferation, migration, and invasion of cancer stem cells in colon cancer by interacting with MYL9 via sponging microRNA-412-3p.Clin Res Hepatol Gastroenterol. 2020 Feb;44(1):101-114. doi: 10.1016/j.clinre.2019.05.001. Epub 2019 Jun 26.
914 Immune Effects of M51R Vesicular Stomatitis Virus Treatment of Carcinomatosis From Colon Cancer.J Surg Res. 2020 Jan;245:127-135. doi: 10.1016/j.jss.2019.07.032. Epub 2019 Aug 12.
915 Ectopic Expression of miR-147 Inhibits Stem Cell Marker and Epithelial-Mesenchymal Transition (EMT)-Related Protein Expression in Colon Cancer Cells.Oncol Res. 2019 Mar 29;27(4):399-406. doi: 10.3727/096504018X15179675206495. Epub 2018 Feb 9.
916 Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.Cancer Sci. 2011 Dec;102(12):2139-49. doi: 10.1111/j.1349-7006.2011.02086.x. Epub 2011 Oct 17.
917 Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinoma.J Cell Biochem. 2010 Jun 1;110(3):687-96. doi: 10.1002/jcb.22579.
918 Vitamin D and the nutritional environment in functions of intestinal stem cells: Implications for tumorigenesis and prevention.J Steroid Biochem Mol Biol. 2020 Apr;198:105556. doi: 10.1016/j.jsbmb.2019.105556. Epub 2019 Nov 26.
919 Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death.Cancers (Basel). 2019 Apr 12;11(4):524. doi: 10.3390/cancers11040524.
920 Liver receptor homologue 1, a novel prognostic marker in colon cancer patients.Oncol Lett. 2018 Sep;16(3):2833-2838. doi: 10.3892/ol.2018.8988. Epub 2018 Jun 18.
921 P4HB knockdown induces human HT29 colon cancer cell apoptosis through the generation of reactive oxygen species and inactivation of STAT3 signaling.Mol Med Rep. 2019 Jan;19(1):231-237. doi: 10.3892/mmr.2018.9660. Epub 2018 Nov 15.
922 Berberine regulates the microRNA-21-ITG4-PDCD4 axis and inhibits colon cancer viability.Oncol Lett. 2018 Apr;15(4):5971-5976. doi: 10.3892/ol.2018.7997. Epub 2018 Feb 8.
923 Oncogenic effect of PHLDB2 is associated with epithelial-mesenchymal transition and E-cadherin regulation in colorectal cancer.Cancer Cell Int. 2019 Jul 16;19:184. doi: 10.1186/s12935-019-0903-1. eCollection 2019.
924 FAPP2 promotes tumor cell growth in human colon cancer through activation of Wnt signaling.Exp Cell Res. 2019 Jan 1;374(1):12-18. doi: 10.1016/j.yexcr.2018.11.002. Epub 2018 Nov 5.
925 An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth.Genes Dev. 2014 May 15;28(10):1068-84. doi: 10.1101/gad.237206.113. Epub 2014 May 1.
926 Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.J Agric Food Chem. 2019 May 1;67(17):4808-4816. doi: 10.1021/acs.jafc.9b00833. Epub 2019 Apr 17.
927 Promoter hypermethylation inactivate tumor suppressor FAM134B and is associated with poor prognosis in colorectal cancer.Genes Chromosomes Cancer. 2018 May;57(5):240-251. doi: 10.1002/gcc.22525. Epub 2018 Jan 30.
928 Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway.Cell Commun Signal. 2019 Jan 25;17(1):9. doi: 10.1186/s12964-018-0316-0.
929 Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients.Sci Rep. 2019 Sep 10;9(1):13008. doi: 10.1038/s41598-019-49477-3.
930 RETRACTED: Long non-coding RNA HULC interacts with miR-613 to regulate colon cancer growth and metastasis through targeting RTKN.Biomed Pharmacother. 2019 Jan;109:2035-2042. doi: 10.1016/j.biopha.2018.08.017. Epub 2018 Nov 26.
931 SATB2 and CDX2 are prognostic biomarkers in DNA mismatch repair protein deficient colon cancer.Mod Pathol. 2019 Jul;32(8):1217-1231. doi: 10.1038/s41379-019-0265-1. Epub 2019 Apr 8.
932 Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer.Cell Death Dis. 2019 Feb 12;10(2):137. doi: 10.1038/s41419-019-1352-4.
933 Epithelial-mesenchymal transition induced by MyoD inhibits growth of high metastatic colorectal cancer.Med Hypotheses. 2019 Sep;130:109285. doi: 10.1016/j.mehy.2019.109285. Epub 2019 Jun 24.
934 MicroRNA-125a inhibits tumorigenesis by targeting Smurf1 in colorectal carcinoma.FEBS Open Bio. 2019 Jul;9(7):1305-1314. doi: 10.1002/2211-5463.12680. Epub 2019 Jun 17.
935 Induction and down-regulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis.Gastroenterology. 2009 Oct;137(4):1346-57. doi: 10.1053/j.gastro.2009.06.041. Epub 2009 Jun 21.
936 Mechano-growth Factor Expression in Colorectal Cancer Investigated With Fluorescent Gold Nanoparticles.Anticancer Res. 2019 Apr;39(4):1705-1710. doi: 10.21873/anticanres.13276.
937 Production of an anti-TM4SF5 monoclonal antibody and its application in the detection of TM4SF5 as a possible marker of a poor prognosis in colorectal cancer.Int J Oncol. 2018 Jul;53(1):275-285. doi: 10.3892/ijo.2018.4385. Epub 2018 Apr 26.
938 Prognostic Role of TMED3 in Clear Cell Renal Cell Carcinoma: A Retrospective Multi-Cohort Analysis.Front Genet. 2019 Apr 17;10:355. doi: 10.3389/fgene.2019.00355. eCollection 2019.
939 TIPE1 impairs stemness maintenance in colorectal cancer through directly targeting -catenin.Carcinogenesis. 2020 Mar 13;41(1):25-35. doi: 10.1093/carcin/bgz079.
940 TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma.Oncotarget. 2017 Mar 28;8(13):21229-21240. doi: 10.18632/oncotarget.15070.
941 TRAPPC9: Novel insights into its trafficking and signaling pathways in health and disease (Review).Int J Mol Med. 2018 Dec;42(6):2991-2997. doi: 10.3892/ijmm.2018.3889. Epub 2018 Sep 21.
942 ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients.Oncol Rep. 2005 May;13(5):907-13.
943 ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2.Autophagy. 2016 Nov;12(11):2167-2182. doi: 10.1080/15548627.2016.1217380. Epub 2016 Aug 25.
944 Identification of proacrosin binding protein sp32 precursor as a human cancer/testis antigen.Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3282-7. doi: 10.1073/pnas.041625098.
945 3'UTR Polymorphism in ACSL1 Gene Correlates with Expression Levels and Poor Clinical Outcome in Colon Cancer Patients.PLoS One. 2016 Dec 19;11(12):e0168423. doi: 10.1371/journal.pone.0168423. eCollection 2016.
946 Fatty acid CoA ligase 4 is up-regulated in colon adenocarcinoma.Cancer Res. 2001 Dec 1;61(23):8429-34.
947 A study of three polymorphic sites of ADA gene in colon cancer.Cancer Invest. 2010 Dec;28(10):989-92. doi: 10.3109/07357907.2010.483501. Epub 2010 Jun 30.
948 The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer.J Cell Sci. 2009 Aug 15;122(Pt 16):2906-13. doi: 10.1242/jcs.050468. Epub 2009 Jul 28.
949 Genetic inactivation of ADAMTS15 metalloprotease in human colorectal cancer.Cancer Res. 2009 Jun 1;69(11):4926-34. doi: 10.1158/0008-5472.CAN-08-4155. Epub 2009 May 19.
950 Adamts18 deficiency promotes colon carcinogenesis by enhancing -catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer.Oncotarget. 2017 Mar 21;8(12):18979-18990. doi: 10.18632/oncotarget.14866.
951 ADAMTSL3/punctin-2, a gene frequently mutated in colorectal tumors, is widely expressed in normal and malignant epithelial cells, vascular endothelial cells and other cell types, and its mRNA is reduced in colon cancer.Int J Cancer. 2007 Oct 15;121(8):1710-6. doi: 10.1002/ijc.22882.
952 Elevated Adenylyl Cyclase 9 Expression Is a Potential Prognostic Biomarker for Patients with Colon Cancer.Med Sci Monit. 2018 Jan 2;24:19-25. doi: 10.12659/msm.906002.
953 Effects of genetic variations in the adiponectin pathway genes on the risk of colorectal cancer in the Chinese population.BMC Med Genet. 2011 Jul 12;12:94. doi: 10.1186/1471-2350-12-94.
954 Expression of adiponectin receptors, AdipoR1 and AdipoR2, in normal colon epithelium and colon cancer tissue.Oncol Rep. 2008 Sep;20(3):479-83.
955 ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.Clin Cancer Res. 2017 Jun 1;23(11):2769-2780. doi: 10.1158/1078-0432.CCR-16-1604. Epub 2016 Nov 30.
956 Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.Biochim Biophys Acta. 2014 Mar;1843(3):618-28. doi: 10.1016/j.bbamcr.2013.12.013.
957 MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.Genes Dev. 2019 Sep 1;33(17-18):1236-1251. doi: 10.1101/gad.327056.119. Epub 2019 Aug 15.
958 Transcriptome profiling analysis reveals biomarkers in colon cancer samples of various differentiation.Oncol Lett. 2018 Jul;16(1):48-54. doi: 10.3892/ol.2018.8668. Epub 2018 May 8.
959 Screening for possible miRNA-mRNA associations in a colon cancer cell line.Gene. 2014 Jan 10;533(2):520-31. doi: 10.1016/j.gene.2013.08.005. Epub 2013 Aug 9.
960 Long non-coding RNA CASC7 inhibits the proliferation and migration of colon cancer cells via inhibiting microRNA-21.Biomed Pharmacother. 2017 Nov;95:1644-1653. doi: 10.1016/j.biopha.2017.09.052. Epub 2017 Oct 6.
961 Regulation of CD40 signaling in colon cancer cells and its implications in clinical tissues.Cancer Immunol Immunother. 2016 Aug;65(8):919-29. doi: 10.1007/s00262-016-1847-0. Epub 2016 Jun 4.
962 Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.Glycobiology. 2009 Jul;19(7):726-34. doi: 10.1093/glycob/cwp040. Epub 2009 Mar 17.
963 PKA RI/A-kinase anchoring proteins 10 signaling pathway and the prognosis of colorectal cancer.J Gastroenterol Hepatol. 2015 Mar;30(3):496-503. doi: 10.1111/jgh.12689.
964 A-kinase anchor protein 12 (AKAP12) inhibits cell migration in breast cancer.Exp Mol Pathol. 2018 Dec;105(3):364-370. doi: 10.1016/j.yexmp.2018.10.010. Epub 2018 Oct 30.
965 Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma.Oncol Rep. 2012 Nov;28(5):1792-8. doi: 10.3892/or.2012.2002. Epub 2012 Aug 30.
966 A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.J Exp Clin Cancer Res. 2015 Nov 21;34:142. doi: 10.1186/s13046-015-0258-y.
967 ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status.Br J Cancer. 2018 Jan;118(2):224-232. doi: 10.1038/bjc.2017.363. Epub 2017 Dec 12.
968 Therapeutic opportunities in colon cancer: Focus on phosphodiesterase inhibitors.Life Sci. 2019 Aug 1;230:150-161. doi: 10.1016/j.lfs.2019.05.043. Epub 2019 May 21.
969 Molecular cloning of complementary DNAs encoding alkaline phosphatase in human colon cancer cells.Cancer Res. 1990 Feb 15;50(4):1085-91.
970 Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers.PLoS One. 2019 Mar 15;14(3):e0209392. doi: 10.1371/journal.pone.0209392. eCollection 2019.
971 AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.Nat Commun. 2014 Aug 1;5:4557. doi: 10.1038/ncomms5557.
972 Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells.Mol Cancer. 2006 Nov 17;5:63. doi: 10.1186/1476-4598-5-63.
973 The expression of MAGE and SSX, and correlation of COX2, VEGF, and survivin in colorectal cancer.Anticancer Res. 2012 Feb;32(2):559-64.
974 Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated.Cell Cycle. 2009 Nov 15;8(22):3770-6. doi: 10.4161/cc.8.22.10066. Epub 2009 Nov 14.
975 TAZ expression as a prognostic indicator in colorectal cancer.PLoS One. 2013;8(1):e54211. doi: 10.1371/journal.pone.0054211. Epub 2013 Jan 23.
976 Piroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathway.Nutr Cancer. 2012 Apr;64(3):409-18. doi: 10.1080/01635581.2012.655402. Epub 2012 Feb 27.
977 Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.Cancer Res. 2002 Oct 15;62(20):5651-6.
978 Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs.Biochim Biophys Acta. 2002 May 3;1575(1-3):54-62. doi: 10.1016/s0167-4781(02)00250-6.
979 Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.J Cell Physiol. 2010 Jul;224(1):33-40. doi: 10.1002/jcp.22085.
980 Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.PLoS One. 2013 Dec 30;8(12):e83629. doi: 10.1371/journal.pone.0083629. eCollection 2013.
981 Tumor Suppressive Role of ARHGAP17 in Colon Cancer Through Wnt/-Catenin Signaling.Cell Physiol Biochem. 2018;46(5):2138-2148. doi: 10.1159/000489543. Epub 2018 Apr 28.
982 Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis.Int J Oncol. 2014 Jan;44(1):211-21. doi: 10.3892/ijo.2013.2150. Epub 2013 Oct 25.
983 Activation of TIM1 induces colon cancer cell apoptosis via modulating Fas ligand expression.Biochem Biophys Res Commun. 2016 Apr 29;473(2):377-81. doi: 10.1016/j.bbrc.2016.02.085. Epub 2016 Feb 26.
984 Inhibition of Growth and Metastasis of Colon Cancer by Delivering 5-Fluorouracil-loaded Pluronic P85 Copolymer Micelles.Sci Rep. 2016 Feb 11;6:20896. doi: 10.1038/srep20896.
985 ARID3A Positivity Correlated With Favorable Prognosis in Patients With Residual Rectal Cancer After Neoadjuvant Chemoradiotherapy.Anticancer Res. 2019 Jun;39(6):2845-2853. doi: 10.21873/anticanres.13413.
986 P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis.Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6334-9. doi: 10.1073/pnas.0911082107. Epub 2010 Mar 22.
987 Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and 1 integrin/FAK-mediated signalling.Biochem Biophys Res Commun. 2018 Sep 5;503(2):843-848. doi: 10.1016/j.bbrc.2018.06.085. Epub 2018 Jun 21.
988 Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50.Mol Cancer Ther. 2009 Jun;8(6):1613-24. doi: 10.1158/1535-7163.MCT-08-0694. Epub 2009 Jun 9.
989 ASF1A regulates H4(Y72) phosphorylation and promotes autophagy in colon cancer cells via a kinase activity.Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2754-2763. doi: 10.1080/21691401.2019.1617725.
990 Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer.Cell Rep. 2018 May 15;23(7):1962-1976. doi: 10.1016/j.celrep.2018.04.053.
991 ATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy.Cancer Manag Res. 2019 Dec 9;11:10275-10285. doi: 10.2147/CMAR.S226828. eCollection 2019.
992 lncRNA KCNQ1OT1 enhances the chemoresistance of oxaliplatin in colon cancer by targeting the miR-34a/ATG4B pathway.Onco Targets Ther. 2019 Apr 9;12:2649-2660. doi: 10.2147/OTT.S188054. eCollection 2019.
993 Colorectal cancer-derived extracellular vesicles induce transformation of fibroblasts into colon carcinoma cells.J Exp Clin Cancer Res. 2019 Jun 14;38(1):257. doi: 10.1186/s13046-019-1248-2.
994 MicroRNA-613 promotes colon cancer cell proliferation, invasion and migration by targeting ATOH1.Biochem Biophys Res Commun. 2018 Oct 12;504(4):827-833. doi: 10.1016/j.bbrc.2018.09.054. Epub 2018 Sep 13.
995 Epigenetic regulation of the human ATP2A3 gene promoter in gastric and colon cancer cell lines.Mol Carcinog. 2019 Jun;58(6):887-897. doi: 10.1002/mc.22978. Epub 2019 Jan 29.
996 Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells.Carcinogenesis. 2009 Nov;30(11):1962-9. doi: 10.1093/carcin/bgp223. Epub 2009 Sep 15.
997 ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients.J Clin Med. 2019 Jul 21;8(7):1070. doi: 10.3390/jcm8071070.
998 Identification and characterization of functional single nucleotide polymorphisms (SNPs) in Axin 1 gene: a molecular dynamics approach.Cell Biochem Biophys. 2018 Jun;76(1-2):173-185. doi: 10.1007/s12013-017-0818-1. Epub 2017 Aug 2.
999 A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer.FEBS Lett. 2005 Jan 3;579(1):71-8. doi: 10.1016/j.febslet.2004.11.037.
1000 1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells.Oncotarget. 2014 Jun 15;5(11):3673-84. doi: 10.18632/oncotarget.1981.
1001 Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.PLoS One. 2018 Apr 26;13(4):e0196245. doi: 10.1371/journal.pone.0196245. eCollection 2018.
1002 BAD-mediated apoptotic pathway is associated with human cancer development.Int J Mol Med. 2015 Apr;35(4):1081-7. doi: 10.3892/ijmm.2015.2091. Epub 2015 Feb 5.
1003 Magnetic gold nanoparticle-mediated small interference RNA silencing Bag-1 gene for colon cancer therapy.Oncol Rep. 2016 Feb;35(2):978-84. doi: 10.3892/or.2015.4453. Epub 2015 Nov 26.
1004 A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.Gastroenterology. 2009 Jul;137(1):165-75. doi: 10.1053/j.gastro.2009.03.041. Epub 2009 Mar 26.
1005 Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer.Sci Rep. 2016 May 20;6:26273. doi: 10.1038/srep26273.
1006 Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells.Sci Immunol. 2017 May 19;2(11):eaal1713. doi: 10.1126/sciimmunol.aal1713.
1007 A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and of the Lutheran blood group glycoprotein.Blood. 1996 Sep 1;88(5):1865-72.
1008 Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status.Int J Cancer. 2002 Apr 1;98(4):498-504. doi: 10.1002/ijc.10146.
1009 Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after -irradiation through Wnt/-catenin pathway.Carcinogenesis. 2015 Jun;36(6):622-31. doi: 10.1093/carcin/bgv044. Epub 2015 Mar 31.
1010 HCRP-1 regulates EGFR-AKT-BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer.Cell Death Dis. 2018 Dec 5;9(12):1176. doi: 10.1038/s41419-018-1217-2.
1011 Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene BCL2L12 in colon cancer.Biol Chem. 2008 Dec;389(12):1467-75. doi: 10.1515/BC.2008.173.
1012 BCL9-2 promotes early stages of intestinal tumor progression.Gastroenterology. 2011 Oct;141(4):1359-70, 1370.e1-3. doi: 10.1053/j.gastro.2011.06.039. Epub 2011 Jun 23.
1013 Novel method for high throughput DNA methylation marker evaluation using PNA-probe library hybridization and MALDI-TOF detection.Nucleic Acids Res. 2006 May 2;34(8):e59. doi: 10.1093/nar/gkl218.
1014 The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer.J Transl Med. 2009 Aug 20;7:71. doi: 10.1186/1479-5876-7-71.
1015 Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target.Mol Cell Proteomics. 2011 Dec;10(12):M111.011353. doi: 10.1074/mcp.M111.011353. Epub 2011 Jul 25.
1016 Prevalence of breast and colorectal cancer in Ashkenazi Jewish carriers of Fanconi anemia and Bloom syndrome.Isr Med Assoc J. 2007 Dec;9(12):847-50.
1017 2'-benzoyloxycinnamaldehyde induces apoptosis in human carcinoma via reactive oxygen species.J Biol Chem. 2004 Feb 20;279(8):6911-20. doi: 10.1074/jbc.M309708200. Epub 2003 Dec 3.
1018 BMP3 suppresses colon tumorigenesis via ActRIIB/SMAD2-dependent and TAK1/JNK signaling pathways.J Exp Clin Cancer Res. 2019 Oct 28;38(1):428. doi: 10.1186/s13046-019-1435-1.
1019 The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types.Radiother Oncol. 2015 Sep;116(3):346-51. doi: 10.1016/j.radonc.2015.06.028. Epub 2015 Jul 10.
1020 Antimicrobial susceptibilities of specific syndromes created with organ-specific weighted incidence antibiograms (OSWIA) in patients with intra-abdominal infections.BMC Infect Dis. 2018 Nov 19;18(1):584. doi: 10.1186/s12879-018-3494-x.
1021 A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients.Oncol Rep. 2007 May;17(5):1089-94.
1022 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.Oncotarget. 2017 Oct 9;8(58):98623-98634. doi: 10.18632/oncotarget.21697. eCollection 2017 Nov 17.
1023 BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.J Clin Invest. 2011 Oct;121(10):4056-69. doi: 10.1172/JCI44228. Epub 2011 Sep 12.
1024 Suppression of core 1 Gal-transferase is associated with reduction of TF and reciprocal increase of Tn, sialyl-Tn and Core 3 glycans in human colon cancer cells.PLoS One. 2013;8(3):e59792. doi: 10.1371/journal.pone.0059792. Epub 2013 Mar 25.
1025 Anticancer activity of synthetic ()-kusunokinin and its derivative ()-bursehernin on human cancer cell lines.Biomed Pharmacother. 2019 Sep;117:109115. doi: 10.1016/j.biopha.2019.109115. Epub 2019 Jun 17.
1026 Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice.Cancer Biol Ther. 2013 Jul;14(7):672-8. doi: 10.4161/cbt.25089. Epub 2013 May 31.
1027 Down-regulation of tumor suppressor in lung cancer 1 (TSLC1) expression correlates with poor prognosis in patients with colon cancer.J Mol Histol. 2012 Dec;43(6):715-21. doi: 10.1007/s10735-012-9438-7. Epub 2012 Aug 1.
1028 A bipartite butyrate-responsive element in the human calretinin (CALB2) promoter acts as a repressor in colon carcinoma cells but not in mesothelioma cells.J Cell Biochem. 2010 Feb 15;109(3):519-31. doi: 10.1002/jcb.22429.
1029 Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.Cancer Res. 2007 Aug 15;67(16):7703-12. doi: 10.1158/0008-5472.CAN-07-0991.
1030 The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line.Int J Oncol. 2007 Oct;31(4):915-22.
1031 The miR-28-5p-CAMTA2 axis regulates colon cancer progression via Wnt/-catenin signaling.J Cell Biochem. 2021 Sep;122(9):945-957. doi: 10.1002/jcb.29536. Epub 2019 Nov 10.
1032 CARMA3 is overexpressed in colon cancer and regulates NF-B activity and cyclin D1 expression.Biochem Biophys Res Commun. 2012 Sep 7;425(4):781-7. doi: 10.1016/j.bbrc.2012.07.152. Epub 2012 Aug 2.
1033 TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.J Biol Chem. 2001 Aug 24;276(34):32220-9. doi: 10.1074/jbc.M100433200. Epub 2001 Jun 14.
1034 CARD9 prevents lung cancer development by suppressing the expansion of myeloid-derived suppressor cells and IDO production.Int J Cancer. 2019 Oct 15;145(8):2225-2237. doi: 10.1002/ijc.32355. Epub 2019 May 6.
1035 Curcumin -D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood.Biol Pharm Bull. 2017;40(9):1515-1524. doi: 10.1248/bpb.b17-00339.
1036 Regional Bias of Intratumoral Genetic Heterogeneity of Apoptosis-Related Genes BAX, APAF1, and FLASH in Colon Cancers with High Microsatellite Instability.Dig Dis Sci. 2015 Jun;60(6):1674-9. doi: 10.1007/s10620-014-3499-2. Epub 2015 Jan 20.
1037 Integral analyses of survival-related long non-coding RNA MIR210HG and its prognostic role in colon cancer.Oncol Lett. 2019 Aug;18(2):1107-1116. doi: 10.3892/ol.2019.10435. Epub 2019 Jun 4.
1038 CBLL1 is highly expressed in non-small cell lung cancer and promotes cell proliferation and invasion.Thorac Cancer. 2019 Jun;10(6):1479-1488. doi: 10.1111/1759-7714.13097. Epub 2019 May 23.
1039 HP1 suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2.Int J Oncol. 2014 Dec;45(6):2541-8. doi: 10.3892/ijo.2014.2646. Epub 2014 Sep 9.
1040 CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.Oncotarget. 2017 Mar 21;8(12):19934-19946. doi: 10.18632/oncotarget.15253.
1041 Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth.Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10213-8. doi: 10.1073/pnas.1221243110. Epub 2013 Jun 3.
1042 m(6)A modification-mediated CBX8 induction regulates stemness and chemosensitivity of colon cancer via upregulation of LGR5.Mol Cancer. 2019 Dec 18;18(1):185. doi: 10.1186/s12943-019-1116-x.
1043 Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells.J Biol Chem. 2009 Jul 31;284(31):20629-37. doi: 10.1074/jbc.M109.014332. Epub 2009 Jun 11.
1044 Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis.Cancer Res. 2017 May 1;77(9):2339-2350. doi: 10.1158/0008-5472.CAN-16-1883. Epub 2017 Mar 1.
1045 Dro1/Ccdc80 inactivation promotes AOM/DSS-induced colorectal carcinogenesis and aggravates colitis by DSS in mice.Carcinogenesis. 2018 Sep 21;39(9):1176-1184. doi: 10.1093/carcin/bgy077.
1046 KP-CoT-23 (CCDC83) is a novel immunogenic cancer/testis antigen in colon cancer.Int J Oncol. 2012 Nov;41(5):1820-6. doi: 10.3892/ijo.2012.1601. Epub 2012 Aug 22.
1047 Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer.FASEB J. 2011 Feb;25(2):590-9. doi: 10.1096/fj.10-167304. Epub 2010 Oct 25.
1048 Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.Cytokine. 2018 Oct;110:435-441. doi: 10.1016/j.cyto.2018.05.015. Epub 2018 May 23.
1049 The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury.Stem Cells Int. 2017;2017:4782820. doi: 10.1155/2017/4782820. Epub 2017 Aug 16.
1050 Retroviral cyclin enhances cyclin-dependent kinase-8 activity.J Virol. 2012 May;86(10):5742-51. doi: 10.1128/JVI.07006-11. Epub 2012 Feb 29.
1051 GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis.J Cell Biochem. 2007 Apr 15;100(6):1376-86. doi: 10.1002/jcb.21140.
1052 Identification of specific and common diagnostic antibody markers for gastrointestinal cancers by SEREX screening using testis cDNA phage library.Oncotarget. 2018 Jan 1;9(26):18559-18569. doi: 10.18632/oncotarget.24963. eCollection 2018 Apr 6.
1053 Autumn Royal and Ribier Grape Juice Extracts Reduced Viability and Metastatic Potential of Colon Cancer Cells.Evid Based Complement Alternat Med. 2018 Jan 14;2018:2517080. doi: 10.1155/2018/2517080. eCollection 2018.
1054 Clinical significance of transmembrane 4 superfamily in colon cancer.Br J Cancer. 2003 Jul 7;89(1):158-67. doi: 10.1038/sj.bjc.6601015.
1055 Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of STAT3 in a hypoxic environment.Cell Biosci. 2019 Aug 6;9:62. doi: 10.1186/s13578-019-0325-8. eCollection 2019.
1056 Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells.Med Oncol. 2012 Jun;29(2):915-8. doi: 10.1007/s12032-011-9836-9. Epub 2011 Feb 5.
1057 Down-regulation of liver-intestine cadherin enhances noscapine-induced apoptosis in human colon cancer cells.Expert Rev Anticancer Ther. 2017 Sep;17(9):857-863. doi: 10.1080/14737140.2017.1344097. Epub 2017 Jun 27.
1058 Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation.Carcinogenesis. 2002 Jul;23(7):1139-48. doi: 10.1093/carcin/23.7.1139.
1059 Loss of cadherin related family member 5 (CDHR5) expression in clear cell renal cell carcinoma is a prognostic marker of disease progression.Oncotarget. 2017 Aug 24;8(43):75076-75086. doi: 10.18632/oncotarget.20507. eCollection 2017 Sep 26.
1060 Knockdown of PFTAIRE Protein Kinase 1 (PFTK1) Inhibits Proliferation, Invasion, and EMT in Colon Cancer Cells.Oncol Res. 2016;24(3):137-44. doi: 10.3727/096504016X14611963142218.
1061 EVI1 targets Np63 and upregulates the cyclin dependent kinase inhibitor p21 independent of p53 to delay cell cycle progression and cell proliferation in colon cancer cells.Int J Biochem Cell Biol. 2013 Aug;45(8):1568-76. doi: 10.1016/j.biocel.2013.04.032. Epub 2013 May 9.
1062 Epigenetic Status of CDO1 Gene May Reflect Chemosensitivity in Colon Cancer with Postoperative Adjuvant Chemotherapy.Ann Surg Oncol. 2019 Feb;26(2):406-414. doi: 10.1245/s10434-018-6865-z. Epub 2018 Oct 11.
1063 Induction of nonspecific cross-reacting antigen mRNA by interferon-gamma and anti-fibronectin receptor antibody in colon cancer cells.J Gastroenterol. 1997 Apr;32(2):200-5. doi: 10.1007/BF02936368.
1064 Neutrophil infiltration is a favorable prognostic factor in early stages of colon cancer.Hum Pathol. 2017 Oct;68:193-202. doi: 10.1016/j.humpath.2017.08.028. Epub 2017 Sep 4.
1065 Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers.Exp Mol Pathol. 2015 Jun;98(3):585-92. doi: 10.1016/j.yexmp.2015.03.019. Epub 2015 Mar 13.
1066 S100A4-induced cell motility and metastasis is restricted by the Wnt/-catenin pathway inhibitor calcimycin in colon cancer cells.Mol Biol Cell. 2011 Sep;22(18):3344-54. doi: 10.1091/mbc.E10-09-0739. Epub 2011 Jul 27.
1067 Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells.Int J Cancer. 2007 Nov 15;121(10):2162-71. doi: 10.1002/ijc.22911.
1068 Up-regulation of CHAF1A, a poor prognostic factor, facilitates cell proliferation of colon cancer.Biochem Biophys Res Commun. 2014 Jun 27;449(2):208-15. doi: 10.1016/j.bbrc.2014.05.006. Epub 2014 May 15.
1069 CHTM1 regulates cancer cell sensitivity to metabolic stress via p38-AIF1 pathway.J Exp Clin Cancer Res. 2019 Jun 20;38(1):271. doi: 10.1186/s13046-019-1253-5.
1070 CHI3L1 promotes proliferation and improves sensitivity to cetuximab in colon cancer cells by down-regulating p53.J Clin Lab Anal. 2020 Jan;34(1):e23026. doi: 10.1002/jcla.23026. Epub 2019 Sep 19.
1071 MicroRNA 429 regulates the expression of CHMP5 in the inflammatory colitis and colorectal cancer cells.Inflamm Res. 2018 Dec;67(11-12):985-996. doi: 10.1007/s00011-018-1194-z. Epub 2018 Oct 17.
1072 Synergy between dihydromyricetin intervention and irinotecan chemotherapy delays the progression of colon cancer in mouse models.Food Funct. 2019 Apr 17;10(4):2040-2049. doi: 10.1039/c8fo01756e.
1073 Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.J Biol Chem. 2018 Sep 28;293(39):15163-15177. doi: 10.1074/jbc.RA118.001937. Epub 2018 Aug 9.
1074 DNA Replication and Sister Chromatid Cohesion 1 (DSCC1) of the Replication Factor Complex CTF18-RFC is Critical for Colon Cancer Cell Growth.J Cancer. 2019 Oct 15;10(24):6142-6153. doi: 10.7150/jca.32339. eCollection 2019.
1075 A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion.FEBS Lett. 2007 Dec 22;581(30):5904-10. doi: 10.1016/j.febslet.2007.11.072. Epub 2007 Dec 3.
1076 CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells.Mol Med Rep. 2013 Dec;8(6):1630-4. doi: 10.3892/mmr.2013.1716. Epub 2013 Oct 8.
1077 Creatine kinase brain overexpression protects colorectal cells from various metabolic and non-metabolic stresses.J Cell Biochem. 2011 Apr;112(4):1066-75. doi: 10.1002/jcb.23020.
1078 Gene trapping identifies chloride channel 4 as a novel inducer of colon cancer cell migration, invasion and metastases.Br J Cancer. 2010 Feb 16;102(4):774-82. doi: 10.1038/sj.bjc.6605536. Epub 2010 Jan 19.
1079 Intracellular claudin-1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis.Cancer Sci. 2020 Feb;111(2):700-712. doi: 10.1111/cas.14249. Epub 2019 Dec 20.
1080 HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation.Oncotarget. 2017 Sep 23;8(50):87718-87736. doi: 10.18632/oncotarget.21190. eCollection 2017 Oct 20.
1081 Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.BMC Cancer. 2017 Feb 13;17(1):129. doi: 10.1186/s12885-017-3123-x.
1082 Tetranectin, a plasminogen kringle 4-binding protein. Cloning and gene expression pattern in human colon cancer.Lab Invest. 1992 Aug;67(2):253-62.
1083 DC-SIGN mediates gastric cancer progression by regulating the JAK2/STAT3 signaling pathway and affecting LncRNA RP11-181G12.2 expression.Biomed Pharmacother. 2020 Jan;121:109644. doi: 10.1016/j.biopha.2019.109644. Epub 2019 Nov 19.
1084 Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.Oncogene. 2004 Dec 9;23(57):9289-94. doi: 10.1038/sj.onc.1208100.
1085 Adiponectin represses colon cancer cell proliferation via AdipoR1- and -R2-mediated AMPK activation.Mol Endocrinol. 2010 Jul;24(7):1441-52. doi: 10.1210/me.2009-0498. Epub 2010 May 5.
1086 Up-regulation of CNDP2 facilitates the proliferation of colon cancer.BMC Gastroenterol. 2014 May 21;14:96. doi: 10.1186/1471-230X-14-96.
1087 Calponin 3 promotes invasion and drug resistance of colon cancer cells.World J Gastrointest Oncol. 2019 Nov 15;11(11):971-982. doi: 10.4251/wjgo.v11.i11.971.
1088 Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region.Am J Pathol. 2006 Mar;168(3):856-65. doi: 10.2353/ajpath.2006.050384.
1089 Increasing Incidence of Colon Cancer in the Young: Assessing the Tumor Biology.J Am Coll Surg. 2019 Jul;229(1):79-90. doi: 10.1016/j.jamcollsurg.2019.03.022. Epub 2019 Apr 14.
1090 ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development.Cancer Cell. 2015 Aug 10;28(2):183-97. doi: 10.1016/j.ccell.2015.07.004.
1091 Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells.Mol Cancer. 2015 Oct 13;14:180. doi: 10.1186/s12943-015-0450-x.
1092 Expression of mitochondrial cytochrome c oxidase in human colonic cell differentiation, transformation, and risk for colonic cancer.Cancer Res. 1990 Mar 1;50(5):1596-600.
1093 Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.Cancer Prev Res (Phila). 2011 Dec;4(12):2015-26. doi: 10.1158/1940-6207.CAPR-11-0233. Epub 2011 Sep 1.
1094 Synthesis, docking, cytotoxicity, and LTA(4)H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy.Bioorg Med Chem. 2017 Feb 1;25(3):1277-1285. doi: 10.1016/j.bmc.2016.12.048. Epub 2016 Dec 29.
1095 Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1533-1543. doi: 10.1016/j.bbamcr.2019.07.001. Epub 2019 Jul 10.
1096 Crumbs3 regulates the expression of glycosphingolipids on the plasma membrane to promote colon cancer cell migration.Biochem Biophys Res Commun. 2019 Nov 5;519(2):287-293. doi: 10.1016/j.bbrc.2019.08.161. Epub 2019 Sep 26.
1097 Comparative effectiveness of screening strategies for Lynch syndrome.J Natl Cancer Inst. 2015 Mar 20;107(4):djv005. doi: 10.1093/jnci/djv005. Print 2015 Apr.
1098 The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.Int J Cancer. 2008 Jul 1;123(1):14-21. doi: 10.1002/ijc.23608.
1099 Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.Life Sci. 2002 Feb 8;70(12):1359-67. doi: 10.1016/s0024-3205(01)01519-3.
1100 The role of CT10 regulation of kinase-like in cancer.Future Oncol. 2014 Dec;10(16):2687-97. doi: 10.2217/fon.14.199.
1101 Investigation of apoptotic effect of juglone on CCL-228-SW 480 colon cancer cell line.J Cancer Res Ther. 2019 Jan-Mar;15(1):68-74. doi: 10.4103/jcrt.JCRT_880_17.
1102 Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR.Mol Cell Biochem. 2007 Apr;298(1-2):59-68. doi: 10.1007/s11010-006-9350-0. Epub 2006 Nov 21.
1103 DDA1 promotes stage IIB-IIC colon cancer progression by activating NFB/CSN2/GSK-3 signaling.Oncotarget. 2016 Apr 12;7(15):19794-812. doi: 10.18632/oncotarget.7847.
1104 Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney.Oncogene. 2001 Aug 16;20(36):5062-6. doi: 10.1038/sj.onc.1204603.
1105 Hybrid Method Based on Information Gain and Support Vector Machine for Gene Selection in Cancer Classification.Genomics Proteomics Bioinformatics. 2017 Dec;15(6):389-395. doi: 10.1016/j.gpb.2017.08.002. Epub 2017 Dec 12.
1106 Let?d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway.Int J Oncol. 2018 Aug;53(2):781-790. doi: 10.3892/ijo.2018.4419. Epub 2018 May 23.
1107 Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression.J Biol Chem. 2015 Oct 30;290(44):26533-48. doi: 10.1074/jbc.M115.660175. Epub 2015 Sep 13.
1108 Expression and epigenetic regulation of cystatin B in lung cancer and colorectal cancer.Pathol Res Pract. 2017 Dec;213(12):1568-1574. doi: 10.1016/j.prp.2017.06.007. Epub 2017 Jun 6.
1109 CTHRC1 overexpression predicts poor survival and enhances epithelial-mesenchymal transition in colorectal cancer.Cancer Med. 2018 Nov;7(11):5643-5654. doi: 10.1002/cam4.1807. Epub 2018 Oct 9.
1110 The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells.Oncogene. 1999 Jan 28;18(4):905-15. doi: 10.1038/sj.onc.1202348.
1111 Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.Mol Carcinog. 2017 Jul;56(7):1733-1742. doi: 10.1002/mc.22630. Epub 2017 Mar 6.
1112 High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival.Cell Physiol Biochem. 2018;51(6):2829-2842. doi: 10.1159/000496013. Epub 2018 Dec 18.
1113 Cullin 4B is a novel prognostic marker that correlates with colon cancer progression and pathogenesis.Med Oncol. 2013;30(2):534. doi: 10.1007/s12032-013-0534-7. Epub 2013 May 7.
1114 The Chemokine CXCL16 Is a New Biomarker for Lymph Node Analysis of Colon Cancer Outcome.Int J Mol Sci. 2019 Nov 18;20(22):5793. doi: 10.3390/ijms20225793.
1115 Fibroblast-derived CXCL12/SDF-1 promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer.World J Gastroenterol. 2017 Jul 28;23(28):5167-5178. doi: 10.3748/wjg.v23.i28.5167.
1116 CYB5D2 displays tumor suppression activities towards cervical cancer.Biochim Biophys Acta. 2016 Apr;1862(4):556-565. doi: 10.1016/j.bbadis.2015.12.013. Epub 2015 Dec 12.
1117 CYB5R1 links epithelial-mesenchymal transition and poor prognosis in colorectal cancer.Oncotarget. 2016 May 24;7(21):31350-60. doi: 10.18632/oncotarget.8912.
1118 IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2.Cancer Res. 2011 Mar 15;71(6):2172-82. doi: 10.1158/0008-5472.CAN-10-3295. Epub 2011 Jan 20.
1119 Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1.FEBS Lett. 2016 Feb;590(3):330-9. doi: 10.1002/1873-3468.12063. Epub 2016 Feb 2.
1120 Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1057-1062. doi: 10.1073/pnas.1712625115. Epub 2018 Jan 16.
1121 Oncogenic function of DACT1 in colon cancer through the regulation of -catenin.PLoS One. 2012;7(3):e34004. doi: 10.1371/journal.pone.0034004. Epub 2012 Mar 21.
1122 DACT2 is a functional tumor suppressor through inhibiting Wnt/-catenin pathway and associated with poor survival in colon cancer.Oncogene. 2015 May 14;34(20):2575-85. doi: 10.1038/onc.2014.201. Epub 2014 Jul 14.
1123 Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development.Cancer Lett. 2016 Jun 1;375(2):209-220. doi: 10.1016/j.canlet.2016.02.055. Epub 2016 Mar 7.
1124 Genome-wide association study of colorectal cancer identifies six new susceptibility loci.Nat Commun. 2015 Jul 7;6:7138. doi: 10.1038/ncomms8138.
1125 Construction and characterization of regulated cycle inhibiting factors induced upon Tet-On system in human colon cancer cell lines.Anticancer Drugs. 2018 Oct;29(9):854-860. doi: 10.1097/CAD.0000000000000654.
1126 DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer.Cancer Res. 2013 Jun 15;73(12):3771-82. doi: 10.1158/0008-5472.CAN-12-4069. Epub 2013 Apr 22.
1127 The phospholipase DDHD1 as a new target in colorectal cancer therapy.J Exp Clin Cancer Res. 2018 Apr 13;37(1):82. doi: 10.1186/s13046-018-0753-z.
1128 Involvement of RNA helicases p68 and p72 in colon cancer.Cancer Res. 2007 Aug 15;67(16):7572-8. doi: 10.1158/0008-5472.CAN-06-4652.
1129 DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer.Oncotarget. 2015 Jul 30;6(21):18602-12. doi: 10.18632/oncotarget.4329.
1130 Differential labeling by monoclonal antibodies Adnab-9 and anti-alpha-defensin 5 based on the distribution and adenomatous tissue content of colonic polyps.Dig Dis Sci. 2005 Apr;50(4):708-13. doi: 10.1007/s10620-005-2561-5.
1131 Expression of the human antimicrobial peptide -defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells.Sci Rep. 2018 Dec 21;8(1):18043. doi: 10.1038/s41598-018-36387-z.
1132 Apoptotic Activity of Lactobacillus plantarum DGK-17-Fermented Soybean Seed Extract in Human Colon Cancer Cells via ROS-JNK Signaling Pathway.J Food Sci. 2017 Jun;82(6):1475-1483. doi: 10.1111/1750-3841.13732. Epub 2017 May 10.
1133 The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration.Oncogene. 2017 Mar 2;36(9):1191-1199. doi: 10.1038/onc.2016.282. Epub 2016 Oct 31.
1134 DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation.Cancer Sci. 2009 Oct;100(10):1801-8. doi: 10.1111/j.1349-7006.2009.01246.x. Epub 2009 Jun 17.
1135 Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells.Cancer Lett. 2009 Apr 18;276(2):152-9. doi: 10.1016/j.canlet.2008.11.003. Epub 2008 Dec 6.
1136 Regulation of the oncogenic function of distal-less 4 by microRNA-122 in hepatocellular carcinoma.Mol Med Rep. 2015 Jul;12(1):1375-80. doi: 10.3892/mmr.2015.3554. Epub 2015 Mar 27.
1137 Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor.Int J Mol Med. 2008 Jan;21(1):19-31.
1138 Discovery, synthesis and molecular substantiation of N-(benzo[d]thiazol-2-yl)-2-hydroxyquinoline-4-carboxamides as anticancer agents.Bioorg Chem. 2019 Oct;91:103171. doi: 10.1016/j.bioorg.2019.103171. Epub 2019 Jul 30.
1139 Decreased tumorigenicity of a human colon adenocarcinoma cell line by an antisense expression vector specific for c-Src.Cell Growth Differ. 1997 Mar;8(3):269-74.
1140 Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer.J Exp Clin Cancer Res. 2015 Jun 11;34(1):60. doi: 10.1186/s13046-015-0176-z.
1141 Genetic polymorphisms of dihydropyrimidinase in a Japanese patient with capecitabine-induced toxicity.PLoS One. 2015 Apr 27;10(4):e0124818. doi: 10.1371/journal.pone.0124818. eCollection 2015.
1142 Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer.Phytomedicine. 2019 Aug;61:152813. doi: 10.1016/j.phymed.2018.12.036. Epub 2018 Dec 31.
1143 Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling.Oncogene. 2014 Sep 4;33(36):4531-6. doi: 10.1038/onc.2013.442. Epub 2013 Oct 28.
1144 DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells.Redox Biol. 2018 Jul;17:224-235. doi: 10.1016/j.redox.2018.04.020. Epub 2018 Apr 23.
1145 Differential expression of DUSP2 in left- and right-sided colon cancer is associated with poor prognosis in colorectal cancer.Oncol Lett. 2018 Apr;15(4):4207-4214. doi: 10.3892/ol.2018.7881. Epub 2018 Jan 26.
1146 Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.Nat Commun. 2015 Mar 16;6:6380. doi: 10.1038/ncomms7380.
1147 E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells.J Cell Physiol. 2009 Nov;221(2):350-8. doi: 10.1002/jcp.21859.
1148 Proteomic Analysis of Liquid Biopsy from Tumor-Draining Vein Indicates that High Expression of Exosomal ECM1 Is Associated with Relapse in Stage I-III Colon Cancer.Transl Oncol. 2018 Jun;11(3):715-721. doi: 10.1016/j.tranon.2018.03.010. Epub 2018 Apr 13.
1149 Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer.J Biomed Sci. 2009;16(1):33. doi: 10.1186/1423-0127-16-33. Epub 2008 Dec 25.
1150 Expression of EEF1A1 Is Associated with Prognosis of Patients with Colon Adenocarcinoma.J Clin Med. 2019 Nov 7;8(11):1903. doi: 10.3390/jcm8111903.
1151 Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer.Br J Cancer. 2004 Apr 19;90(8):1620-6. doi: 10.1038/sj.bjc.6601723.
1152 RNA interference-mediated silencing of eukaryotic translation initiation factor 3, subunit B (EIF3B) gene expression inhibits proliferation of colon cancer cells.World J Surg Oncol. 2012 Jun 26;10:119. doi: 10.1186/1477-7819-10-119.
1153 Effect of siRNA-mediated knockdown of eIF3c gene on survival of colon cancer cells.J Zhejiang Univ Sci B. 2013 Jun;14(6):451-9. doi: 10.1631/jzus.B1200230.
1154 hmiR-34c-3p upregulation inhibits the proliferation of colon cancer cells by targeting EIF3D.Anticancer Drugs. 2018 Nov;29(10):975-982. doi: 10.1097/CAD.0000000000000674.
1155 Overexpression of eIF3e is correlated with colon tumor development and poor prognosis.Int J Clin Exp Pathol. 2014 Sep 15;7(10):6462-74. eCollection 2014.
1156 EIF3i promotes colon oncogenesis by regulating COX-2 protein synthesis and -catenin activation.Oncogene. 2014 Aug 7;33(32):4156-63. doi: 10.1038/onc.2013.397. Epub 2013 Sep 23.
1157 eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer.Oncogene. 2011 Jan 27;30(4):398-409. doi: 10.1038/onc.2010.422. Epub 2010 Sep 13.
1158 A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1.Genome Res. 2016 Apr;26(4):541-53. doi: 10.1101/gr.193169.115. Epub 2016 Feb 9.
1159 Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.Carcinogenesis. 2016 Jan;37(1):87-95. doi: 10.1093/carcin/bgv161. Epub 2015 Nov 19.
1160 Functional evidence for Eme1 as a marker of cisplatin resistance.Int J Cancer. 2009 Jun 15;124(12):2997-3001. doi: 10.1002/ijc.24268.
1161 Abrogation of EMILIN1-1 integrin interaction promotes experimental colitis and colon carcinogenesis.Matrix Biol. 2019 Oct;83:97-115. doi: 10.1016/j.matbio.2019.08.006. Epub 2019 Aug 31.
1162 Alkaline sphingomyelinase: an old enzyme with novel implications.Biochim Biophys Acta. 2006 Mar;1761(3):281-91. doi: 10.1016/j.bbalip.2006.03.007. Epub 2006 Mar 30.
1163 The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis.Oncogene. 2013 Sep 26;32(39):4602-13. doi: 10.1038/onc.2012.485. Epub 2012 Oct 29.
1164 Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.Cancer Lett. 2016 Oct 28;381(2):341-8. doi: 10.1016/j.canlet.2016.08.008. Epub 2016 Aug 15.
1165 Unexpected Growth-Promoting Effect of Oxaliplatin in Excision Repair Cross-Complementation Group 1 Transfected Human Colon Cancer Cells.Pharmacology. 2018;102(3-4):161-168. doi: 10.1159/000491587. Epub 2018 Jul 26.
1166 Elevated Expression of ERCC6 Confers Resistance to 5-Fluorouracil and Is Associated with Poor Patient Survival in Colorectal Cancer.DNA Cell Biol. 2017 Sep;36(9):781-786. doi: 10.1089/dna.2017.3768. Epub 2017 Jun 30.
1167 ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion.Biochem Biophys Res Commun. 2006 Jun 23;345(1):216-21. doi: 10.1016/j.bbrc.2006.04.094. Epub 2006 Apr 27.
1168 Common genetic variation in ETV6 is associated with colorectal cancer susceptibility.Nat Commun. 2016 May 5;7:11478. doi: 10.1038/ncomms11478.
1169 DNA Methylation Analysis Using Droplet Digital PCR.Methods Mol Biol. 2018;1768:363-383. doi: 10.1007/978-1-4939-7778-9_21.
1170 Exo70 is an independent prognostic factor in colon cancer.Sci Rep. 2017 Jul 11;7(1):5039. doi: 10.1038/s41598-017-05308-x.
1171 FABP7 promotes cell proliferation and survival in colon cancer through MEK/ERK signaling pathway.Biomed Pharmacother. 2018 Dec;108:119-129. doi: 10.1016/j.biopha.2018.08.038. Epub 2018 Sep 13.
1172 Mutation of FADD gene is rare in human colon and stomach cancers.APMIS. 2004 Sep;112(9):595-7. doi: 10.1111/j.1600-0463.2004.apm1120906.x.
1173 A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression.Cancer Lett. 2013 Jan 28;328(2):278-84. doi: 10.1016/j.canlet.2012.09.026. Epub 2012 Oct 8.
1174 Promoter hypermethylation mediated downregulation of FBP1 in human hepatocellular carcinoma and colon cancer. PLoS One. 2011;6(10):e25564. doi: 10.1371/journal.pone.0025564. Epub 2011 Oct 19.
1175 F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway.Biomed Pharmacother. 2018 Nov;107:1712-1719. doi: 10.1016/j.biopha.2018.08.119. Epub 2018 Sep 8.
1176 Identification of BCP-20 (FBXO39) as a cancer/testis antigen from colon cancer patients by SEREX.Biochem Biophys Res Commun. 2011 May 6;408(2):195-201. doi: 10.1016/j.bbrc.2011.02.077. Epub 2011 Feb 19.
1177 Gene expression analysis in colorectal cancer using practical DNA array filter.Dis Colon Rectum. 2001 Feb;44(2):295-9. doi: 10.1007/BF02234309.
1178 RACK1 downregulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells.Cancer Biol Ther. 2009 Dec;8(23):2297-305. doi: 10.4161/cbt.8.23.10262. Epub 2009 Dec 7.
1179 FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of -catenin transcriptional activity.Oncogene. 2017 Mar 30;36(13):1779-1792. doi: 10.1038/onc.2016.339. Epub 2016 Sep 19.
1180 Molecular cloning and characterization of human FGF-20 on chromosome 8p21.3-p22.Biochem Biophys Res Commun. 2000 Aug 2;274(2):337-43. doi: 10.1006/bbrc.2000.3142.
1181 Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation.Nucleic Acids Res. 2014 Mar;42(5):2932-44. doi: 10.1093/nar/gkt1286. Epub 2013 Dec 10.
1182 ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer.Tumour Biol. 2017 Mar;39(3):1010428317695024. doi: 10.1177/1010428317695024.
1183 Clinical significance and comparison of flotillin 1 expression in left and right colon cancer.Oncol Lett. 2019 Aug;18(2):997-1004. doi: 10.3892/ol.2019.10401. Epub 2019 May 27.
1184 Enhancement of anti-tumor effect of plasmid DNA-carrying MUC1 by the adjuvanticity of FLT3L in mouse model.Immunopharmacol Immunotoxicol. 2018 Aug;40(4):353-357. doi: 10.1080/08923973.2018.1498099. Epub 2018 Aug 15.
1185 Silibinin inhibits the invasion of IL-6-stimulated colon cancer cells via selective JNK/AP-1/MMP-2 modulation in vitro.J Agric Food Chem. 2012 Dec 26;60(51):12451-7. doi: 10.1021/jf300964f. Epub 2012 Dec 13.
1186 2-Amino-4-(1-piperidine) pyridine exhibits inhibitory effect on colon cancer through suppression of FOXA2 expression.3 Biotech. 2019 Nov;9(11):384. doi: 10.1007/s13205-019-1915-1. Epub 2019 Oct 4.
1187 Forkhead Box Protein J1 (FOXJ1) is Overexpressed in Colorectal Cancer and Promotes Nuclear Translocation of -Catenin in SW620 Cells.Med Sci Monit. 2017 Feb 17;23:856-866. doi: 10.12659/msm.902906.
1188 Knockdown of FOXK1 alone or in combination with apoptosis-inducing 5-FU inhibits cell growth in colorectal cancer.Oncol Rep. 2016 Oct;36(4):2151-9. doi: 10.3892/or.2016.5041. Epub 2016 Aug 25.
1189 Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells.Oncotarget. 2017 Feb 7;8(6):9783-9793. doi: 10.18632/oncotarget.14189.
1190 Follistatin-like protein 1 sustains colon cancer cell growth and survival.Oncotarget. 2018 Jul 27;9(58):31278-31290. doi: 10.18632/oncotarget.25811. eCollection 2018 Jul 27.
1191 The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.Int J Biochem Cell Biol. 2011 Jan;43(1):130-9. doi: 10.1016/j.biocel.2010.10.004. Epub 2010 Oct 19.
1192 Post-translational glycoprotein modifications regulate colon cancer stem cells and colon adenoma progression in Apc(min/+) mice through altered Wnt receptor signaling.J Biol Chem. 2014 Nov 7;289(45):31534-49. doi: 10.1074/jbc.M114.602680. Epub 2014 Oct 1.
1193 Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manag Res. 2009 Apr 3;1:25-37.
1194 LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer.Br J Cancer. 2013 Aug 20;109(4):994-1003. doi: 10.1038/bjc.2013.364. Epub 2013 Jul 30.
1195 Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway.Cancers (Basel). 2019 Apr 10;11(4):505. doi: 10.3390/cancers11040505.
1196 Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?.BMC Cancer. 2010 May 5;10:180. doi: 10.1186/1471-2407-10-180.
1197 Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12921-5. doi: 10.1073/pnas.0901454106. Epub 2009 Jul 17.
1198 MiR-4262 promotes cell apoptosis and inhibits proliferation of colon cancer cells: involvement of GALNT4.Am J Transl Res. 2018 Dec 15;10(12):3969-3977. eCollection 2018.
1199 De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.J Biol Chem. 2018 Jan 26;293(4):1298-1314. doi: 10.1074/jbc.M117.812826. Epub 2017 Nov 29.
1200 The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients.Oncotarget. 2017 Jan 17;8(3):4747-4759. doi: 10.18632/oncotarget.13580.
1201 Associations between vitamin D-binding protein isotypes, circulating 25(OH)D levels, and vitamin D metabolite uptake in colon cancer cells.Cancer Prev Res (Phila). 2014 Apr;7(4):426-34. doi: 10.1158/1940-6207.CAPR-13-0269. Epub 2014 Jan 28.
1202 Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer.FEBS Lett. 2017 Jul;591(13):1902-1917. doi: 10.1002/1873-3468.12685. Epub 2017 Jun 10.
1203 Clinical relevance of the differential expression of the glycosyltransferase gene GCNT3 in colon cancer.Eur J Cancer. 2015 Jan;51(1):1-8. doi: 10.1016/j.ejca.2014.10.021. Epub 2014 Nov 11.
1204 Neoexpression of N-cadherin in E-cadherin positive colon cancers.Int J Cancer. 2004 Sep 20;111(5):711-9. doi: 10.1002/ijc.20317.
1205 Augmenter of liver regeneration gene expression in human colon cancer cell lines and clinical tissue samples.J BUON. 2015 Jan-Feb;20(1):84-91.
1206 PSF3 marks malignant colon cancer and has a role in cancer cell proliferation.Biochem Biophys Res Commun. 2010 Feb 5;392(2):150-4. doi: 10.1016/j.bbrc.2009.12.174. Epub 2010 Jan 6.
1207 Epigenetic silencing of glutaminase 2 in human liver and colon cancers.BMC Cancer. 2013 Dec 14;13:601. doi: 10.1186/1471-2407-13-601.
1208 Absence of GNAI2 codon 179 oncogene mutations in inflammatory bowel disease.Inflamm Bowel Dis. 2000 May;6(2):103-6. doi: 10.1097/00054725-200005000-00006.
1209 GOLPH3 expression promotes the resistance of HT29 cells to 5fluorouracil by activating multiple signaling pathways.Mol Med Rep. 2018 Jan;17(1):542-548. doi: 10.3892/mmr.2017.7877. Epub 2017 Oct 25.
1210 Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.Lab Invest. 1993 Jun;68(6):663-75.
1211 Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.Int J Cancer. 2017 Jun 15;140(12):2728-2733. doi: 10.1002/ijc.30687. Epub 2017 Mar 28.
1212 The clinical significance of circulating GPC1 positive exosomes and its regulative miRNAs in colon cancer patients.Oncotarget. 2017 Aug 24;8(60):101189-101202. doi: 10.18632/oncotarget.20516. eCollection 2017 Nov 24.
1213 Phospholipase D activation mediates growth and migration of colon cancer cells interacting with cancer-associated fibroblasts.Cell Mol Biol (Noisy-le-grand). 2018 Nov 30;64(14):84-88.
1214 Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.Nat Genet. 2012 May 27;44(7):770-6. doi: 10.1038/ng.2293.
1215 Anti-sense RNA of 32-kDa laminin-binding protein inhibits attachment and invasion of a human colon carcinoma cell line.J Surg Res. 1992 Apr;52(4):340-6. doi: 10.1016/0022-4804(92)90113-e.
1216 Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.Oncogene. 2008 Jun 5;27(25):3624-34. doi: 10.1038/sj.onc.1211021. Epub 2008 Jan 28.
1217 In vitro-fermented raw and roasted walnuts induce expression of CAT and GSTT2 genes, growth inhibition, and apoptosis in LT97 colon adenoma cells.Nutr Res. 2017 Nov;47:72-80. doi: 10.1016/j.nutres.2017.09.004. Epub 2017 Sep 18.
1218 Can colorectal cancer be prevented or treated by oral hormone replacement therapy?.Curr Mol Pharmacol. 2009 Nov;2(3):285-92. doi: 10.2174/1874467210902030285.
1219 Integrative epigenome analysis identifies a Polycomb-targeted differentiation program as a tumor-suppressor event epigenetically inactivated in colorectal cancer.Cell Death Dis. 2014 Jul 17;5(7):e1324. doi: 10.1038/cddis.2014.283.
1220 FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes.Anticancer Agents Med Chem. 2013 May;13(4):584-94. doi: 10.2174/1871520611313040008.
1221 Tim-3 suppresses the killing effect of V9V2T cells on colon cancer cells by reducing perforin and granzyme B expression.Exp Cell Res. 2020 Jan 1;386(1):111719. doi: 10.1016/j.yexcr.2019.111719. Epub 2019 Nov 11.
1222 A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function.Mol Cell Biol. 2012 May;32(9):1654-70. doi: 10.1128/MCB.06033-11. Epub 2012 Feb 27.
1223 Fucosylation Deficiency in Mice Leads to Colitis andAdenocarcinoma.Gastroenterology. 2017 Jan;152(1):193-205.e10. doi: 10.1053/j.gastro.2016.09.004. Epub 2016 Sep 14.
1224 Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.Int J Mol Med. 2016 Sep;38(3):776-84. doi: 10.3892/ijmm.2016.2689. Epub 2016 Jul 22.
1225 Chromosome 5 allele loss at the glucocorticoid receptor locus in human colorectal carcinomas.Biochem Biophys Res Commun. 1988 Jan 29;150(2):591-8. doi: 10.1016/0006-291x(88)90434-2.
1226 Methylation of the Tumor Suppressor Genes HIC1 and RassF1A Clusters Independently From the Methylation of Polycomb Target Genes in Colon Cancer.Ann Surg Oncol. 2017 Feb;24(2):578-585. doi: 10.1245/s10434-015-5024-z. Epub 2015 Dec 15.
1227 Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival.J Clin Invest. 2002 Aug;110(3):351-60. doi: 10.1172/JCI15529.
1228 Comparative study of gene expression by cDNA microarray in human colorectal cancer tissues and normal mucosa.Int J Oncol. 2006 Jul;29(1):83-94.
1229 Loss of HLTF function promotes intestinal carcinogenesis.Mol Cancer. 2012 Mar 27;11:18. doi: 10.1186/1476-4598-11-18.
1230 Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction.Jpn J Cancer Res. 1999 Sep;90(9):987-92. doi: 10.1111/j.1349-7006.1999.tb00846.x.
1231 The Prognostic Value of m6A RNA Methylation Regulators in Colon Adenocarcinoma.Med Sci Monit. 2019 Dec 11;25:9435-9445. doi: 10.12659/MSM.920381.
1232 Oncogenic heterogeneous nuclear ribonucleoprotein D-like promotes the growth of human colon cancer SW620 cells via its regulation of cell-cycle.Acta Biochim Biophys Sin (Shanghai). 2018 Sep 1;50(9):880-887. doi: 10.1093/abbs/gmy085.
1233 Interferon regulatory factor 1 and a variant of heterogeneous nuclear ribonucleoprotein L coordinately silence the gene for adhesion protein CEACAM1.J Biol Chem. 2018 Jun 15;293(24):9277-9291. doi: 10.1074/jbc.RA117.001507. Epub 2018 May 2.
1234 HNRNPLL, a newly identified colorectal cancer metastasis suppressor, modulates alternative splicing of CD44 during epithelial-mesenchymal transition.Gut. 2018 Jun;67(6):1103-1111. doi: 10.1136/gutjnl-2016-312927. Epub 2017 Mar 30.
1235 hnRNPM induces translation switch under hypoxia to promote colon cancer development.EBioMedicine. 2019 Mar;41:299-309. doi: 10.1016/j.ebiom.2019.02.059. Epub 2019 Mar 7.
1236 HOXA3 promotes tumor growth of human colon cancer through activating EGFR/Ras/Raf/MEK/ERK signaling pathway.J Cell Biochem. 2018 Mar;119(3):2864-2874. doi: 10.1002/jcb.26461. Epub 2017 Dec 12.
1237 Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.J Cell Physiol. 2018 Feb;233(2):727-735. doi: 10.1002/jcp.25981. Epub 2017 Jul 11.
1238 The Significant Pathways and Genes Underlying the Colon Cancer Treatment by the Traditional Chinese Medicine PHY906.Evid Based Complement Alternat Med. 2017;2017:8753815. doi: 10.1155/2017/8753815. Epub 2017 May 15.
1239 Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.Nat Genet. 2013 Feb;45(2):191-6. doi: 10.1038/ng.2505. Epub 2012 Dec 23.
1240 HSP110 promotes colorectal cancer growth through STAT3 activation.Oncogene. 2017 Apr 20;36(16):2328-2336. doi: 10.1038/onc.2016.403. Epub 2016 Nov 7.
1241 Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy.Genomics. 2015 Dec;106(6):348-54. doi: 10.1016/j.ygeno.2015.10.002. Epub 2015 Oct 21.
1242 KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis.Clin Cancer Res. 2011 Jun 1;17(11):3558-68. doi: 10.1158/1078-0432.CCR-10-2729. Epub 2011 Apr 29.
1243 Increased IFRD1 Expression in Human Colon Cancers Predicts Reduced Patient Survival.Dig Dis Sci. 2017 Dec;62(12):3460-3467. doi: 10.1007/s10620-017-4819-0. Epub 2017 Nov 1.
1244 Long noncoding RNA HOTAIR silencing inhibits invasion and proliferation of human colon cancer LoVo cells via regulating IGF2BP2.J Cell Biochem. 2019 Feb;120(2):1221-1231. doi: 10.1002/jcb.27079. Epub 2018 Oct 18.
1245 Insulin-like growth factor binding protein-4 gene therapy increases apoptosis by altering Bcl-2 and Bax proteins and decreases angiogenesis in colorectal cancer.Int J Oncol. 2007 Apr;30(4):883-8.
1246 Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through 51 Integrin.J Cell Biochem. 2015 Oct;116(10):2385-96. doi: 10.1002/jcb.25189.
1247 Screening of Differentiation-Specific Molecular Biomarkers for Colon Cancer.Cell Physiol Biochem. 2018;46(6):2543-2550. doi: 10.1159/000489660. Epub 2018 May 5.
1248 Delivery of a Modified mRNA Encoding IL-22 Binding Protein (IL-22BP) for Colon Cancer Gene Therapy.J Biomed Nanotechnol. 2018 Jul 1;14(7):1239-1251. doi: 10.1166/jbn.2018.2577.
1249 NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.Dig Dis Sci. 2014 Jun;59(6):1169-79. doi: 10.1007/s10620-014-3168-5. Epub 2014 May 6.
1250 Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue.Oncotarget. 2017 Dec 15;9(3):3432-3445. doi: 10.18632/oncotarget.23289. eCollection 2018 Jan 9.
1251 Cytotoxic, Anti-Proliferative and Apoptosis Activity of l-Amino Acid Oxidase from Malaysian Cryptelytrops purpureomaculatus (CP-LAAO) Venom on Human Colon Cancer Cells.Molecules. 2018 Jun 8;23(6):1388. doi: 10.3390/molecules23061388.
1252 Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer.Scand J Immunol. 2013 Apr;77(4):255-60. doi: 10.1111/sji.12032.
1253 Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor.Cytogenet Cell Genet. 1998;83(3-4):232-5. doi: 10.1159/000015188.
1254 ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.Int J Cancer. 2009 Sep 15;125(6):1306-15. doi: 10.1002/ijc.24437.
1255 ING4 is negatively correlated with microvessel density in colon cancer.Tumour Biol. 2012 Dec;33(6):2357-64. doi: 10.1007/s13277-012-0498-9. Epub 2012 Sep 28.
1256 Therapeutic advantage of genetically engineered Salmonella typhimurium carrying short hairpin RNA against inhibin alpha subunit in cancer treatment.Ann Oncol. 2018 Sep 1;29(9):2010-2017. doi: 10.1093/annonc/mdy240.
1257 INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.Oncotarget. 2017 Dec 6;8(70):115041-115053. doi: 10.18632/oncotarget.22984. eCollection 2017 Dec 29.
1258 Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.Biochem Pharmacol. 2009 Sep 15;78(6):561-72. doi: 10.1016/j.bcp.2009.05.001. Epub 2009 May 9.
1259 Insulin-induced gene 2 expression correlates with colorectal cancer metastasis and disease outcome.IUBMB Life. 2016 Jan;68(1):65-71. doi: 10.1002/iub.1461. Epub 2015 Dec 10.
1260 PINCH-2 presents functional copy number variation and suppresses migration of colon cancer cells by paracrine activity.Int J Cancer. 2015 May 15;136(10):2273-83. doi: 10.1002/ijc.29273. Epub 2014 Oct 30.
1261 Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion.Int J Cancer. 2010 Jun 1;126(11):2563-74. doi: 10.1002/ijc.24987.
1262 IRAK2 counterbalances oncogenic Smurf1 in colon cancer cells by dictating ER stress.Cell Signal. 2018 Aug;48:69-80. doi: 10.1016/j.cellsig.2018.05.001. Epub 2018 May 9.
1263 Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression.J Biol Chem. 2003 Nov 21;278(47):46278-87. doi: 10.1074/jbc.M304721200. Epub 2003 Sep 12.
1264 Insulin receptor substrate-4 is overexpressed in colorectal cancer and promotes retinoblastoma-cyclin-dependent kinase activation.J Gastroenterol. 2018 Aug;53(8):932-944. doi: 10.1007/s00535-018-1432-8. Epub 2018 Jan 20.
1265 The iroquois homeobox gene 5 is regulated by 1,25-dihydroxyvitamin D3 in human prostate cancer and regulates apoptosis and the cell cycle in LNCaP prostate cancer cells.Clin Cancer Res. 2008 Jun 1;14(11):3562-70. doi: 10.1158/1078-0432.CCR-07-4649.
1266 Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer.Oncotarget. 2018 Jan 9;9(8):7902-7917. doi: 10.18632/oncotarget.24083. eCollection 2018 Jan 30.
1267 Chemokine (C-C Motif) Ligand 5 is Involved in Tumor-Associated Dendritic Cell-Mediated Colon Cancer Progression Through Non-Coding RNA MALAT-1.J Cell Physiol. 2015 Aug;230(8):1883-94. doi: 10.1002/jcp.24918.
1268 Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype.Epigenetics. 2014 Sep;9(9):1290-301. doi: 10.4161/epi.32089. Epub 2014 Aug 4.
1269 Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line.J Hum Genet. 2007;52(12):978-984. doi: 10.1007/s10038-007-0204-8. Epub 2007 Oct 13.
1270 Jade family PHD finger 3 (JADE3) increases cancer stem cell-like properties and tumorigenicity in colon cancer.Cancer Lett. 2018 Aug 1;428:1-11. doi: 10.1016/j.canlet.2018.04.012. Epub 2018 Apr 13.
1271 Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells.Cell Commun Signal. 2017 Jun 21;15(1):24. doi: 10.1186/s12964-017-0178-x.
1272 JARID2 inhibits leukemia cell proliferation by regulating CCND1 expression.Int J Hematol. 2015 Jul;102(1):76-85. doi: 10.1007/s12185-015-1797-x. Epub 2015 May 5.
1273 Lysyl-tRNA synthetase-expressing colon spheroids induce M2 macrophage polarization to promote metastasis.J Clin Invest. 2018 Nov 1;128(11):5034-5055. doi: 10.1172/JCI99806. Epub 2018 Oct 8.
1274 Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells.Carcinogenesis. 2005 Nov;26(11):1988-98. doi: 10.1093/carcin/bgi159. Epub 2005 Jun 23.
1275 Interaction of 14-3-3 with KCMF1 suppresses the proliferation and colony formation of human colon cancer stem cells.World J Gastroenterol. 2013 Jun 28;19(24):3770-80. doi: 10.3748/wjg.v19.i24.3770.
1276 Role of JMJD2B in colon cancer cell survival under glucose-deprived conditions and the underlying mechanisms. Oncogene. 2018 Jan 18;37(3):389-402.
1277 Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome.Mol Cancer Ther. 2017 Feb;16(2):397-407. doi: 10.1158/1535-7163.MCT-16-0588. Epub 2016 Dec 15.
1278 Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets.Cancer Res. 2002 Jul 15;62(14):4041-7.
1279 Kruppel-like factor 2 mediated anti-proliferative and anti-metastasis effects of simvastatin in p53 mutant colon cancer.Biochem Biophys Res Commun. 2019 Apr 16;511(4):772-779. doi: 10.1016/j.bbrc.2019.02.127. Epub 2019 Mar 2.
1280 The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition.Theranostics. 2019 Apr 13;9(10):2754-2767. doi: 10.7150/thno.33395. eCollection 2019.
1281 Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay.Tumour Biol. 2019 Jul;41(7):1010428319860728. doi: 10.1177/1010428319860728.
1282 Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer.J Exp Clin Cancer Res. 2015 Dec 1;34:145. doi: 10.1186/s13046-015-0261-3.
1283 Clinical value of a diagnostic score for colon cancer based on serum CEA, CA19-9, cytokeratin-1 and mucin-1.Br J Biomed Sci. 2018 Jul;75(3):122-127. doi: 10.1080/09674845.2018.1456309. Epub 2018 May 8.
1284 Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model.Int Immunopharmacol. 2017 Jan;42:122-129. doi: 10.1016/j.intimp.2016.11.017. Epub 2016 Nov 29.
1285 REG Controls Hippo Signaling and Reciprocal NF-B-YAP Regulation to Promote Colon Cancer.Clin Cancer Res. 2018 Apr 15;24(8):2015-2025. doi: 10.1158/1078-0432.CCR-17-2986. Epub 2018 Feb 6.
1286 LAYN Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric and Colon Cancers.Front Immunol. 2019 Jan 29;10:6. doi: 10.3389/fimmu.2019.00006. eCollection 2019.
1287 Phytohemagglutinin-L (PHA-L) lectin surface binding of N-linked beta 1-6 carbohydrate and its relationship to activated mutant ras in human pancreatic cancer cell lines.Cancer Lett. 1996 Oct 22;107(2):285-91. doi: 10.1016/0304-3835(96)04386-8.
1288 The tumor-associated antigen 90K/Mac-2-binding protein secreted by human colon carcinoma cells enhances extracellular levels of promatrilysin and is a novel substrate of matrix metalloproteinases-2, -7 (matrilysin) and -9: Implications of proteolytic cleavage.Biochim Biophys Acta. 2010 Mar;1800(3):336-43. doi: 10.1016/j.bbagen.2009.07.030. Epub 2009 Aug 7.
1289 Human galectin-8 isoforms and cancer.Glycoconj J. 2002;19(7-9):557-63. doi: 10.1023/B:GLYC.0000014086.38343.98.
1290 Galectin-9 Expression Predicts Favorable Clinical Outcome in Solid Tumors: A Systematic Review and Meta-Analysis.Front Physiol. 2018 Apr 26;9:452. doi: 10.3389/fphys.2018.00452. eCollection 2018.
1291 Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.Hum Mol Genet. 2014 Sep 1;23(17):4729-37. doi: 10.1093/hmg/ddu177. Epub 2014 Apr 15.
1292 DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target.Cancer Res. 2010 Mar 1;70(5):1766-72. doi: 10.1158/0008-5472.CAN-09-3263. Epub 2010 Feb 9.
1293 LIN28B promotes the progression of colon cancer by increasing B-cell lymphoma 2 expression.Biomed Pharmacother. 2018 Jul;103:355-361. doi: 10.1016/j.biopha.2018.04.002. Epub 2018 Apr 24.
1294 Downregulation of hepatic lipase is associated with decreased CD133 expression and clone formation in HepG2 cells.Int J Mol Med. 2018 Oct;42(4):2137-2144. doi: 10.3892/ijmm.2018.3756. Epub 2018 Jul 4.
1295 Loss of Hugl-1 expression associates with lymph node metastasis in endometrial cancer.Oncol Res. 2007;16(9):431-5. doi: 10.3727/000000007783980855.
1296 Overexpression of lamin B1 induces mitotic catastrophe in colon cancer LoVo cells and is associated with worse clinical outcomes.Int J Oncol. 2018 Jan;52(1):89-102. doi: 10.3892/ijo.2017.4182. Epub 2017 Nov 1.
1297 High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.PLoS One. 2017 Sep 28;12(9):e0185607. doi: 10.1371/journal.pone.0185607. eCollection 2017.
1298 A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.Int J Oncol. 2006 Aug;29(2):341-7.
1299 A Unique Nonsaccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.Mol Cancer Ther. 2019 Jan;18(1):51-61. doi: 10.1158/1535-7163.MCT-18-0104. Epub 2018 Oct 18.
1300 Down-regulation of LRP1B in colon cancer promoted the growth and migration of cancer cells.Exp Cell Res. 2017 Aug 1;357(1):1-8. doi: 10.1016/j.yexcr.2017.04.010. Epub 2017 Apr 11.
1301 Prognostic value of LISCH7 mRNA in plasma and tumor of colon cancer patients.Clin Cancer Res. 2007 Nov 1;13(21):6351-8. doi: 10.1158/1078-0432.CCR-07-0882.
1302 Anti-Cancerous Potential of Polysaccharide Fractions Extracted from Peony Seed Dreg on Various Human Cancer Cell Lines Via Cell Cycle Arrest and Apoptosis.Front Pharmacol. 2017 Mar 3;8:102. doi: 10.3389/fphar.2017.00102. eCollection 2017.
1303 Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer.Oncol Rep. 2011 Aug;26(2):343-8. doi: 10.3892/or.2011.1312. Epub 2011 May 20.
1304 Genome-wide association study of colorectal cancer in Hispanics.Carcinogenesis. 2016 Jun;37(6):547-556. doi: 10.1093/carcin/bgw046. Epub 2016 Apr 18.
1305 MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer.Oncotarget. 2018 Jun 29;9(50):29445-29452. doi: 10.18632/oncotarget.25655. eCollection 2018 Jun 29.
1306 Differential regulation and predictive potential of MacroH2A1 isoforms in colon cancer.Am J Pathol. 2012 Jun;180(6):2516-26. doi: 10.1016/j.ajpath.2012.02.027. Epub 2012 Apr 27.
1307 Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer.Int J Cancer. 2007 Jan 1;120(1):207-11. doi: 10.1002/ijc.22155.
1308 MAEL expression links epithelial-mesenchymal transition and stem cell properties in colorectal cancer.Int J Cancer. 2016 Dec 1;139(11):2502-11. doi: 10.1002/ijc.30388. Epub 2016 Aug 29.
1309 RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer.Gastroenterology. 2010 Jan;138(1):231-40.e1-5. doi: 10.1053/j.gastro.2009.08.001. Epub 2009 Aug 15.
1310 Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.Oncotarget. 2017 May 2;8(33):54604-54615. doi: 10.18632/oncotarget.17554. eCollection 2017 Aug 15.
1311 Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress.Cell Death Dis. 2017 Jul 27;8(7):e2957. doi: 10.1038/cddis.2017.347.
1312 Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene.Int J Oncol. 2002 Nov;21(5):1021-6.
1313 MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/-catenin signaling.Mol Cancer. 2018 Aug 1;17(1):111. doi: 10.1186/s12943-018-0848-3.
1314 c-Myc inactivation by mutant Max alters growth and morphology of NCI-H-630 colon cancer cells.J Cell Physiol. 1996 Oct;169(1):200-8. doi: 10.1002/(SICI)1097-4652(199610)169:1<200::AID-JCP20>3.0.CO;2-F.
1315 The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.Oncotarget. 2016 May 10;7(19):28624-36. doi: 10.18632/oncotarget.8721.
1316 Frameshift mutations in the MBD4/MED1 gene in primary gastric cancer with high-frequency microsatellite instability.Cancer Lett. 2002 Jul 8;181(1):115-20. doi: 10.1016/s0304-3835(02)00043-5.
1317 Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells.Mol Cell Biol. 2018 May 15;38(11):e00573-17. doi: 10.1128/MCB.00573-17. Print 2018 Jun 1.
1318 G protein-coupled receptor kinase 5 mediates Tazarotene-induced gene 1-induced growth suppression of human colon cancer cells.BMC Cancer. 2011 May 17;11:175. doi: 10.1186/1471-2407-11-175.
1319 MAP1D, a novel methionine aminopeptidase family member is overexpressed in colon cancer.Oncogene. 2006 Jun 8;25(24):3471-8. doi: 10.1038/sj.onc.1209383. Epub 2006 Mar 27.
1320 Frameshift Mutations in Repeat Sequences of ANK3, HACD4, TCP10L, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 Genes in Colon Cancers.Pathol Oncol Res. 2018 Jul;24(3):617-622. doi: 10.1007/s12253-017-0287-2. Epub 2017 Aug 12.
1321 Loss of microfibril-associated protein 5 (MFAP5) expression in colon cancer stroma.Virchows Arch. 2020 Mar;476(3):383-390. doi: 10.1007/s00428-019-02649-y. Epub 2019 Aug 18.
1322 miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition.Onco Targets Ther. 2017 Dec 22;11:67-74. doi: 10.2147/OTT.S113359. eCollection 2018.
1323 Expression profiling and interferon-beta regulation of liver metastases in colorectal cancer cells.Clin Exp Metastasis. 2002;19(6):541-50. doi: 10.1023/a:1020325327461.
1324 Lycopene, sulforaphane, quercetin, and curcumin applied together show improved antiproliferative potential in colon cancer cells in vitro.J Food Biochem. 2019 Apr;43(4):e12802. doi: 10.1111/jfbc.12802. Epub 2019 Feb 11.
1325 Association of Mixed Lineage Kinase Domain-Like Protein Expression With Prognosis in Patients With Colon Cancer.Technol Cancer Res Treat. 2017 Aug;16(4):428-434. doi: 10.1177/1533034616655909. Epub 2016 Jul 18.
1326 MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties.J Biol Chem. 2007 Jul 27;282(30):21998-2010. doi: 10.1074/jbc.M701737200. Epub 2007 May 18.
1327 Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro.Med Sci Monit. 2018 Oct 28;24:7710-7718. doi: 10.12659/MSM.911002.
1328 MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1.Cancer Sci. 2019 Jan;110(1):135-146. doi: 10.1111/cas.13863. Epub 2018 Dec 21.
1329 N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells.Cells. 2019 Aug 4;8(8):828. doi: 10.3390/cells8080828.
1330 A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.Mol Biol Cell. 2008 Apr;19(4):1693-705. doi: 10.1091/mbc.e07-09-0975. Epub 2008 Feb 6.
1331 The oncogenic effects of p53-inducible gene 3 (PIG3) in colon cancer cells.Korean J Physiol Pharmacol. 2017 Mar;21(2):267-273. doi: 10.4196/kjpp.2017.21.2.267. Epub 2017 Feb 21.
1332 Myocardin-related transcription factor A (MRTF-A) mediates doxorubicin-induced PERP transcription in colon cancer cells.Biochem Biophys Res Commun. 2018 Sep 10;503(3):1732-1739. doi: 10.1016/j.bbrc.2018.07.106. Epub 2018 Aug 2.
1333 Decreased expression of MS4A12 inhibits differentiation and predicts early stage survival in colon cancer.Neoplasma. 2017;64(1):65-73. doi: 10.4149/neo_2017_108.
1334 Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p.Br J Cancer. 2018 Sep;119(6):744-755. doi: 10.1038/s41416-018-0254-z. Epub 2018 Sep 17.
1335 ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK.Oncol Lett. 2019 Jun;17(6):5251-5260. doi: 10.3892/ol.2019.10192. Epub 2019 Mar 27.
1336 MiR-590-3p promotes proliferation and metastasis of colorectal cancer via Hippo pathway.Oncotarget. 2017 Jul 22;8(35):58061-58071. doi: 10.18632/oncotarget.19487. eCollection 2017 Aug 29.
1337 Higher farnesyl diphosphate synthase activity in human colorectal cancer inhibition of cellular apoptosis.Oncology. 2004;67(5-6):351-8. doi: 10.1159/000082918.
1338 One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.PLoS One. 2017 Oct 2;12(10):e0185792. doi: 10.1371/journal.pone.0185792. eCollection 2017.
1339 Functions and regulation of MUC13 mucin in colon cancer cells.J Gastroenterol. 2014 Oct;49(10):1378-91. doi: 10.1007/s00535-013-0885-z. Epub 2013 Oct 7.
1340 Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.J Transl Med. 2018 Sep 20;16(1):259. doi: 10.1186/s12967-018-1632-2.
1341 Mus81 knockdown sensitizes colon cancer cells to chemotherapeutic drugs by activating CHK1 pathway.Clin Res Hepatol Gastroenterol. 2017 Oct;41(5):592-601. doi: 10.1016/j.clinre.2017.01.011. Epub 2017 Mar 11.
1342 MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression.Nat Commun. 2017 Feb 17;8:14448. doi: 10.1038/ncomms14448.
1343 Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca(2+) signalling.Cell Mol Life Sci. 2017 May;74(10):1907-1921. doi: 10.1007/s00018-016-2441-5. Epub 2016 Dec 24.
1344 Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.Nat Genet. 2010 Nov;42(11):973-7. doi: 10.1038/ng.670. Epub 2010 Oct 24.
1345 Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis.Oncogenesis. 2019 Mar 8;8(3):21. doi: 10.1038/s41389-019-0130-6.
1346 Diverse roles of arrest defective 1 in cancer development.Arch Pharm Res. 2019 Dec;42(12):1040-1051. doi: 10.1007/s12272-019-01195-0. Epub 2019 Dec 7.
1347 Downregulation of microRNA-1 and microRNA-145 contributes synergistically to the development of colon cancer.Int J Mol Med. 2015 Dec;36(6):1630-8. doi: 10.3892/ijmm.2015.2364. Epub 2015 Oct 9.
1348 NCAPH plays important roles in human colon cancer.Cell Death Dis. 2017 Mar 16;8(3):e2680. doi: 10.1038/cddis.2017.88.
1349 NDC80 promotes proliferation and metastasis of colon cancer cells.Genet Mol Res. 2016 May 6;15(2). doi: 10.4238/gmr.15028312.
1350 Tumor suppressor candidate gene, NDRG2 is frequently inactivated in human glioblastoma multiforme.Mol Med Rep. 2014 Aug;10(2):891-6. doi: 10.3892/mmr.2014.2237. Epub 2014 May 14.
1351 Characterization of human colon cancer antigens recognized by autologous antibodies.Int J Cancer. 1998 May 29;76(5):652-8. doi: 10.1002/(sici)1097-0215(19980529)76:5<652::aid-ijc7>3.0.co;2-p.
1352 Netrin-4 Mediates Corneal Hemangiogenesis but Not Lymphangiogenesis in the Mouse-Model of Suture-Induced Neovascularization.Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1387-1396. doi: 10.1167/iovs.16-19249.
1353 Nuclear factor of activated T-cell activity is associated with metastatic capacity in colon cancer.Cancer Res. 2014 Dec 1;74(23):6947-57. doi: 10.1158/0008-5472.CAN-14-1592. Epub 2014 Oct 15.
1354 Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.Cancer Res. 2012 Sep 1;72(17):4340-50. doi: 10.1158/0008-5472.CAN-11-4155. Epub 2012 Jun 27.
1355 ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line.Cell Death Dis. 2017 Dec 14;8(12):3218. doi: 10.1038/s41419-017-0006-7.
1356 FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding.EBioMedicine. 2019 Jul;45:25-38. doi: 10.1016/j.ebiom.2019.06.022. Epub 2019 Jun 28.
1357 Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer.Mol Cancer. 2007 Feb 28;6:17. doi: 10.1186/1476-4598-6-17.
1358 Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and PARP pathways.Int J Mol Med. 2015 May;35(5):1317-22. doi: 10.3892/ijmm.2015.2125. Epub 2015 Mar 4.
1359 The multifaceted nature of NLRP12.J Leukoc Biol. 2014 Dec;96(6):991-1000. doi: 10.1189/jlb.3RU0514-265RR. Epub 2014 Sep 23.
1360 Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.PLoS One. 2018 Jun 21;13(6):e0199350. doi: 10.1371/journal.pone.0199350. eCollection 2018.
1361 NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury.Mucosal Immunol. 2017 Mar;10(2):434-445. doi: 10.1038/mi.2016.55. Epub 2016 Jun 29.
1362 Impact of Phytolacca americana extracts on gene expression of colon cancer cells.Phytother Res. 2014 Feb;28(2):219-23. doi: 10.1002/ptr.4979. Epub 2013 Apr 4.
1363 Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.J Pathol. 2005 Apr;205(5):623-32. doi: 10.1002/path.1724.
1364 Lentivirus-mediated knockdown of NOB1 suppresses the proliferation of colon cancer cells.Z Gastroenterol. 2014 May;52(5):429-35. doi: 10.1055/s-0033-1356338. Epub 2014 May 13.
1365 Therapeutic effect of the treatment for colorectal cancer with adenoviral vectors mediated estrogen receptor gene therapy combined with thermotherapy.J Cancer Res Clin Oncol. 2014 Apr;140(4):623-32. doi: 10.1007/s00432-014-1611-9. Epub 2014 Feb 15.
1366 NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.Cell Rep. 2019 Jul 30;28(5):1282-1295.e8. doi: 10.1016/j.celrep.2019.06.085.
1367 Clinical Significance of NADPH Oxidase 5 in Human Colon Cancer.Anticancer Res. 2019 Aug;39(8):4405-4410. doi: 10.21873/anticanres.13611.
1368 NADPH Oxidase 1 Activity and ROS Generation Are Regulated by Grb2/Cbl-Mediated Proteasomal Degradation of NoxO1 in Colon Cancer Cells.Cancer Res. 2016 Feb 15;76(4):855-65. doi: 10.1158/0008-5472.CAN-15-1512. Epub 2016 Jan 18.
1369 High efficiency reconstitution of a human-mouse chimeric Fab of CAb-1 antibody specific to human colon cancer.Scand J Immunol. 2008 Jul;68(1):12-21. doi: 10.1111/j.1365-3083.2008.02087.x. Epub 2008 May 13.
1370 Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.Med Sci Monit. 2018 Mar 9;24:1424-1433. doi: 10.12659/msm.909186.
1371 Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis.Genes Dev. 2002 Aug 15;16(16):2058-72. doi: 10.1101/gad.227502.
1372 Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.JCI Insight. 2018 Apr 19;3(8):e91316. doi: 10.1172/jci.insight.91316. eCollection 2018 Apr 19.
1373 Investigation of RIP140 and LCoR as independent markers for poor prognosis in cervical cancer.Oncotarget. 2017 Oct 31;8(62):105356-105371. doi: 10.18632/oncotarget.22187. eCollection 2017 Dec 1.
1374 Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.Gastroenterology. 2009 Jul;137(1):176-87. doi: 10.1053/j.gastro.2009.03.005. Epub 2009 Mar 18.
1375 In vitro and in vivo treatment of colon cancer by VIP antagonists.Regul Pept. 2002 Nov 15;109(1-3):127-33. doi: 10.1016/s0167-0115(02)00195-7.
1376 Nesfatin-1/Nucleobindin-2 Is a Potent Prognostic Marker and Enhances Cell Proliferation, Migration, and Invasion in Bladder Cancer.Dis Markers. 2018 Sep 19;2018:4272064. doi: 10.1155/2018/4272064. eCollection 2018.
1377 Validation and development of MTH1 inhibitors for treatment of cancer.Ann Oncol. 2016 Dec;27(12):2275-2283. doi: 10.1093/annonc/mdw429. Epub 2016 Nov 8.
1378 High NUSAP1 expression predicts poor prognosis in colon cancer.Pathol Res Pract. 2018 Jul;214(7):968-973. doi: 10.1016/j.prp.2018.05.017. Epub 2018 May 22.
1379 miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells.J Immunol Res. 2018 Aug 2;2018:7498514. doi: 10.1155/2018/7498514. eCollection 2018.
1380 O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy.Biochim Biophys Acta. 2011 Apr;1812(4):514-9. doi: 10.1016/j.bbadis.2011.01.009. Epub 2011 Jan 19.
1381 Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells.Digestion. 2008;77(2):79-86. doi: 10.1159/000121441. Epub 2008 Mar 21.
1382 Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy.Clin Cancer Res. 2016 Jul 1;22(13):3298-309. doi: 10.1158/1078-0432.CCR-15-1709. Epub 2016 Feb 9.
1383 Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin.PLoS One. 2008;3(12):e4054. doi: 10.1371/journal.pone.0004054. Epub 2008 Dec 29.
1384 Colon cancer bears overexpression of OTUB1.Pathol Res Pract. 2014 Nov;210(11):770-3. doi: 10.1016/j.prp.2014.05.008. Epub 2014 May 22.
1385 MicroRNA 32 promotes cell proliferation, migration, and suppresses apoptosis in colon cancer cells by targeting OTU domain containing 3.J Cell Biochem. 2019 Nov;120(11):18629-18639. doi: 10.1002/jcb.28874. Epub 2019 Jul 24.
1386 Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination.Cancer Sci. 2017 Apr;108(4):713-718. doi: 10.1111/cas.13179. Epub 2017 Apr 12.
1387 PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer.Oncogene. 2016 Apr 14;35(15):1943-54. doi: 10.1038/onc.2015.259. Epub 2015 Jul 27.
1388 MicroRNA-429 inhibits the migration and invasion of colon cancer cells by targeting PAK6/cofilin signaling.Oncol Rep. 2015 Aug;34(2):707-14. doi: 10.3892/or.2015.4039. Epub 2015 Jun 8.
1389 Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells.Int J Oncol. 2010 Oct;37(4):909-26. doi: 10.3892/ijo_00000742.
1390 Increased susceptibility of vault poly(ADP-ribose) polymerase-deficient mice to carcinogen-induced tumorigenesis.Cancer Res. 2005 Oct 1;65(19):8846-52. doi: 10.1158/0008-5472.CAN-05-0770.
1391 Zinc finger protein 278, a potential oncogene in human colorectal cancer.Acta Biochim Biophys Sin (Shanghai). 2008 Apr;40(4):289-96. doi: 10.1111/j.1745-7270.2008.00405.x.
1392 PAX2 protein induces expression of cyclin D1 through activating AP-1 protein and promotes proliferation of colon cancer cells.J Biol Chem. 2012 Dec 28;287(53):44164-72. doi: 10.1074/jbc.M112.401521. Epub 2012 Nov 7.
1393 PBX3 hypermethylation in peripheral blood leukocytes predicts better prognosis in colorectal cancer: A propensity score analysis.Cancer Med. 2019 Jul;8(8):4001-4011. doi: 10.1002/cam4.2321. Epub 2019 May 29.
1394 PAF and EZH2 induce Wnt/-catenin signaling hyperactivation.Mol Cell. 2013 Oct 24;52(2):193-205. doi: 10.1016/j.molcel.2013.08.028. Epub 2013 Sep 19.
1395 The apoptosis linked gene ALG-2 is dysregulated in tumors of various origin and contributes to cancer cell viability.Mol Oncol. 2008 Apr;1(4):431-9. doi: 10.1016/j.molonc.2007.08.002. Epub 2007 Aug 19.
1396 Pharmacological Inhibition of Casein Kinase 2 Enhances the Effectiveness of PI3K Inhibition in Colon Cancer Cells.Anticancer Res. 2018 Nov;38(11):6195-6200. doi: 10.21873/anticanres.12973.
1397 PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress.Cancer Biol Ther. 2011 Mar 15;11(6):567-73. doi: 10.4161/cbt.11.6.14412. Epub 2011 Mar 15.
1398 The role of PEG3 in the occurrence and prognosis of colon cancer.Onco Targets Ther. 2019 Jul 25;12:6001-6012. doi: 10.2147/OTT.S208060. eCollection 2019.
1399 Reduced expression of PER3 is associated with incidence and development of colon cancer.Ann Surg Oncol. 2012 Sep;19(9):3081-8. doi: 10.1245/s10434-012-2279-5. Epub 2012 Feb 17.
1400 PES1 is transcriptionally regulated by BRD4 and promotes cell proliferation and glycolysis in hepatocellular carcinoma.Int J Biochem Cell Biol. 2018 Nov;104:1-8. doi: 10.1016/j.biocel.2018.08.014. Epub 2018 Aug 29.
1401 Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.Int J Oncol. 2013 Aug;43(2):586-90. doi: 10.3892/ijo.2013.1971. Epub 2013 May 31.
1402 PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas.Mol Oncol. 2015 Feb;9(2):450-62. doi: 10.1016/j.molonc.2014.09.009. Epub 2014 Oct 13.
1403 The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer.Transl Oncol. 2018 Apr;11(2):436-443. doi: 10.1016/j.tranon.2018.01.015. Epub 2018 Feb 21.
1404 MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.Expert Opin Ther Targets. 2015;19(8):1017-26. doi: 10.1517/14728222.2015.1057569. Epub 2015 Jun 24.
1405 Identification and development of long non-coding RNA-associated regulatory network in colorectal cancer.J Cell Mol Med. 2019 Aug;23(8):5200-5210. doi: 10.1111/jcmm.14395. Epub 2019 May 29.
1406 PIASy stimulates HIF1 SUMOylation and negatively regulates HIF1 activity in response to hypoxia.Oncogene. 2010 Oct 14;29(41):5568-78. doi: 10.1038/onc.2010.297. Epub 2010 Jul 26.
1407 Characterization of the human polymeric immunoglobulin receptor (PIGR) 3'UTR and differential expression of PIGR mRNA during colon tumorigenesis.J Biomed Sci. 2003 Nov-Dec;10(6 Pt 2):792-804. doi: 10.1159/000073967.
1408 17-Hydroxy Wortmannin Restores TRAIL's Response by Ameliorating Increased Beclin 1 Level and Autophagy Function in TRAIL-Resistant Colon Cancer Cells.Mol Cancer Ther. 2019 Jul;18(7):1265-1277. doi: 10.1158/1535-7163.MCT-18-1241. Epub 2019 May 15.
1409 Interaction between physical activity, PITX1 rs647161 genetic polymorphism and colorectal cancer risk in a Korean population: a case-control study.Oncotarget. 2018 Jan 10;9(7):7590-7603. doi: 10.18632/oncotarget.24136. eCollection 2018 Jan 26.
1410 Circulating PIWI-Interacting RNAs piR-5937 and piR-28876 Are Promising Diagnostic Biomarkers of Colon Cancer.Cancer Epidemiol Biomarkers Prev. 2018 Sep;27(9):1019-1028. doi: 10.1158/1055-9965.EPI-18-0318. Epub 2018 Jul 5.
1411 Piwil2 modulates the proliferation and metastasis of colon cancer via regulation of matrix metallopeptidase 9 transcriptional activity.Exp Biol Med (Maywood). 2012 Oct;237(10):1231-40. doi: 10.1258/ebm.2012.011380. Epub 2012 Oct 26.
1412 Multistage risk models and the age pattern in familial polyposis coli.Cancer Invest. 1984;2(6):443-8. doi: 10.3109/07357908409048517.
1413 The human PKP2/plakophilin-2 gene is induced by Wnt/-catenin in normal and colon cancer-associated fibroblasts.Int J Cancer. 2018 Feb 15;142(4):792-804. doi: 10.1002/ijc.31104. Epub 2017 Oct 31.
1414 Group III phospholipase A(2) promotes colitis and colorectal cancer.Sci Rep. 2017 Sep 25;7(1):12261. doi: 10.1038/s41598-017-12434-z.
1415 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.Carcinogenesis. 2018 May 3;39(5):652-660. doi: 10.1093/carcin/bgy026.
1416 PLD4 promotes M1 macrophages to perform antitumor effects in colon cancer cells.Oncol Rep. 2017 Jan;37(1):408-416. doi: 10.3892/or.2016.5216. Epub 2016 Nov 3.
1417 A common gene variant in PLS3 predicts colon cancer recurrence in women.Tumour Biol. 2013 Aug;34(4):2183-8. doi: 10.1007/s13277-013-0754-7. Epub 2013 Apr 3.
1418 A 15-gene signature for prediction of colon cancer recurrence and prognosis based on SVM.Gene. 2017 Mar 10;604:33-40. doi: 10.1016/j.gene.2016.12.016. Epub 2016 Dec 18.
1419 Enhanced Tumoral MLH1-Expression in MLH1-/PMS2-Deficient Colon Cancer Is Indicative of Sporadic Colon Cancer and Not HNPCC.Pathol Oncol Res. 2020 Jul;26(3):1435-1439. doi: 10.1007/s12253-018-00571-3. Epub 2019 Jan 6.
1420 Podocalyxin-Like Protein 1 Regulates TAZ Signaling and Stemness Properties in Colon Cancer.Int J Mol Sci. 2017 Sep 23;18(10):2047. doi: 10.3390/ijms18102047.
1421 Human CAP10-Like Protein 46kDa Gene Promotes Malignancy in Colorectal Cancer.OMICS. 2017 May;21(5):266-274. doi: 10.1089/omi.2017.0037.
1422 Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.J Hum Genet. 2019 Aug;64(8):729-740. doi: 10.1038/s10038-019-0611-7. Epub 2019 May 14.
1423 Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin.Oncotarget. 2017 Apr 4;8(14):22759-22771. doi: 10.18632/oncotarget.15191.
1424 PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways.Oncotarget. 2017 Apr 24;8(35):58611-58624. doi: 10.18632/oncotarget.17381. eCollection 2017 Aug 29.
1425 Circular RNA circ-FOXM1 facilitates cell progression as ceRNA to target PPDPF and MACC1 by sponging miR-1304-5p in non-small cell lung cancer.Biochem Biophys Res Commun. 2019 May 21;513(1):207-212. doi: 10.1016/j.bbrc.2019.03.213. Epub 2019 Apr 4.
1426 Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma.Biomed Pharmacother. 2017 Mar;87:366-374. doi: 10.1016/j.biopha.2016.12.103. Epub 2017 Jan 6.
1427 Wild-type and mutant p53 differentially modulate miR-124/iASPP feedback following pohotodynamic therapy in human colon cancer cell line.Cell Death Dis. 2017 Oct 12;8(10):e3096. doi: 10.1038/cddis.2017.477.
1428 PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas.Leuk Lymphoma. 2001 Mar;41(1-2):177-83. doi: 10.3109/10428190109057968.
1429 Amiloride modulates urokinase gene expression at both transcription and post-transcription levels in human colon cancer cells.Clin Exp Metastasis. 1995 May;13(3):196-202. doi: 10.1007/BF00132208.
1430 DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.Cancer Res. 2009 Sep 15;69(18):7412-21. doi: 10.1158/0008-5472.CAN-09-0116. Epub 2009 Sep 1.
1431 MiR-223-3p promotes the proliferation, invasion and migration of colon cancer cells by negative regulating PRDM1.Am J Transl Res. 2019 Jul 15;11(7):4516-4523. eCollection 2019.
1432 Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma.Br J Cancer. 2001 Mar 23;84(6):743-7. doi: 10.1054/bjoc.2000.1667.
1433 Induction of radioprotective peroxiredoxin-I by ionizing irradiation.J Neurosci Res. 2002 Dec 15;70(6):794-8. doi: 10.1002/jnr.10435.
1434 Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancer.BMB Rep. 2015 Oct;48(10):539-40. doi: 10.5483/bmbrep.2015.48.10.179.
1435 A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells.Sci Rep. 2018 Feb 28;8(1):3770. doi: 10.1038/s41598-018-22090-6.
1436 AMPK2 knockout enhances tumour inflammation through exacerbated liver injury and energy deprivation-associated AMPK1 activation.J Cell Mol Med. 2019 Mar;23(3):1687-1697. doi: 10.1111/jcmm.13978. Epub 2019 Jan 12.
1437 Impact of protamine I on colon cancer proliferation, invasion, migration, diagnosis and prognosis.Biol Chem. 2018 Feb 23;399(3):265-275. doi: 10.1515/hsz-2017-0222.
1438 Protein arginine methyltransferase 8 gene enhances the colon cancer stem cell (CSC) function by upregulating the pluripotency transcription factor.J Cancer. 2018 Apr 6;9(8):1394-1402. doi: 10.7150/jca.23835. eCollection 2018.
1439 PROX1 promotes metabolic adaptation and fuels outgrowth of Wnt(high) metastatic colon cancer cells.Cell Rep. 2014 Sep 25;8(6):1957-1973. doi: 10.1016/j.celrep.2014.08.041. Epub 2014 Sep 18.
1440 Downregulation of LncRNA-RP11-317J10.2 promotes cell proliferation and invasion and predicts poor prognosis in colorectal cancer.Scand J Gastroenterol. 2018 Jan;53(1):38-45. doi: 10.1080/00365521.2017.1392597. Epub 2017 Oct 26.
1441 PRR14 overexpression promotes cell growth, epithelial to mesenchymal transition and metastasis of colon cancer via the AKT pathway.PLoS One. 2019 Oct 9;14(10):e0218839. doi: 10.1371/journal.pone.0218839. eCollection 2019.
1442 The identification of specific methylation patterns across different cancers.PLoS One. 2015 Mar 16;10(3):e0120361. doi: 10.1371/journal.pone.0120361. eCollection 2015.
1443 Inhibition of PRRX2 suppressed colon cancer liver metastasis via inactivation of Wnt/-catenin signaling pathway.Pathol Res Pract. 2019 Oct;215(10):152593. doi: 10.1016/j.prp.2019.152593. Epub 2019 Aug 11.
1444 Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer.BMC Cancer. 2006 Oct 20;6:250. doi: 10.1186/1471-2407-6-250.
1445 Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.J Immunol. 2002 Jul 15;169(2):1102-9. doi: 10.4049/jimmunol.169.2.1102.
1446 Downregulated miR-585-3p promotes cell growth and proliferation in colon cancer by upregulating PSME3.Onco Targets Ther. 2019 Aug 14;12:6525-6534. doi: 10.2147/OTT.S203175. eCollection 2019.
1447 Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH.Nat Cell Biol. 2014 Jul;16(7):685-94. doi: 10.1038/ncb2977. Epub 2014 Jun 1.
1448 PTPN12 Affects Nasopharyngeal Carcinoma Cell Proliferation and Migration Through Regulating EGFR.Cancer Biother Radiopharm. 2018 Mar;33(2):60-64. doi: 10.1089/cbr.2017.2254.
1449 Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer.Eur J Hum Genet. 2011 Mar;19(3):307-12. doi: 10.1038/ejhg.2010.187. Epub 2010 Dec 8.
1450 Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence.Sci Rep. 2015 Apr 24;5:9633. doi: 10.1038/srep09633.
1451 Tumour suppressor function of protein tyrosine phosphatase receptor-T.Biosci Rep. 2011 Oct;31(5):303-7. doi: 10.1042/BSR20100134.
1452 PTTG1 attenuates drug-induced cellular senescence.PLoS One. 2011;6(8):e23754. doi: 10.1371/journal.pone.0023754. Epub 2011 Aug 17.
1453 CD155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells.J Cell Mol Med. 2018 Jan;22(1):131-140. doi: 10.1111/jcmm.13301. Epub 2017 Aug 16.
1454 Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer.Biol Chem. 2018 Oct 25;399(11):1285-1295. doi: 10.1515/hsz-2018-0002.
1455 Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes.Proc Natl Acad Sci U S A. 2007 May 8;104(19):8023-8. doi: 10.1073/pnas.0700720104. Epub 2007 Apr 26.
1456 Hypoxia-induced Rab11-family interacting protein4expression promotes migration and invasion of colon cancer and correlates with poor prognosis.Mol Med Rep. 2018 Mar;17(3):3797-3806. doi: 10.3892/mmr.2017.8283. Epub 2017 Dec 15.
1457 Epidermal growth factor-mediated Rab25 pathway regulates integrin 1 trafficking in colon cancer.Cancer Cell Int. 2018 Mar 5;18:32. doi: 10.1186/s12935-018-0526-y. eCollection 2018.
1458 A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome.BMC Cancer. 2019 Jun 21;19(1):613. doi: 10.1186/s12885-019-5845-4.
1459 Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.Nat Commun. 2019 Dec 13;10(1):5349. doi: 10.1038/s41467-019-13082-9.
1460 Isolation of a novel member of small G protein superfamily and its expression in colon cancer.World J Gastroenterol. 2003 Aug;9(8):1719-24. doi: 10.3748/wjg.v9.i8.1719.
1461 Impaired nonhomologous end-joining in mismatch repair-deficient colon carcinomas.Lab Invest. 2005 Sep;85(9):1130-8. doi: 10.1038/labinvest.3700315.
1462 3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.PLoS One. 2015 Jul 6;10(7):e0131125. doi: 10.1371/journal.pone.0131125. eCollection 2015.
1463 Frequent somatic demethylation of RAPGEF1/C3G intronic sequences in gastrointestinal and gynecological cancer.Int J Oncol. 2011 Jun;38(6):1575-7. doi: 10.3892/ijo.2011.972. Epub 2011 Mar 11.
1464 Association between chronic kidney disease and cancer mortality: A report from the ALLHAT.Clin Nephrol. 2017 Jan;87 (2017)(1):11-20. doi: 10.5414/CN108949.
1465 RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXR/SREBP1c pathway.Biol Res. 2019 Dec 17;52(1):60. doi: 10.1186/s40659-019-0268-x.
1466 RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-B pathway.Cancer Biol Ther. 2019;20(4):435-443. doi: 10.1080/15384047.2018.1529117. Epub 2018 Oct 25.
1467 Expression analysis and association of RBBP6 with apoptosis in colon cancers.J Mol Histol. 2016 Apr;47(2):169-82. doi: 10.1007/s10735-016-9663-6. Epub 2016 Feb 23.
1468 CtIP, a candidate tumor susceptibility gene is a team player with luminaries.Biochim Biophys Acta. 2006 Jan;1765(1):67-73. doi: 10.1016/j.bbcan.2005.09.002. Epub 2005 Oct 6.
1469 Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements.BMC Syst Biol. 2008 Aug 10;2:72. doi: 10.1186/1752-0509-2-72.
1470 RBP7 is a clinically prognostic biomarker and linked to tumor invasion and EMT in colon cancer.J Cancer. 2019 Aug 27;10(20):4883-4891. doi: 10.7150/jca.35180. eCollection 2019.
1471 RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells.Biosci Rep. 2011 Oct;31(5):363-9. doi: 10.1042/BSR20100108.
1472 Anastomotic recurrence of colon cancer: Genetic analysis challenges the widely held theories of cancerous cells' intraluminal implantation and metachronous carcinogenesis.J Surg Oncol. 2016 Aug;114(2):228-36. doi: 10.1002/jso.24282. Epub 2016 May 9.
1473 Synthesis and Anticancer Activity Evaluation of Hydrolyzed Derivatives of Panaxnotoginseng Saponins.Molecules. 2018 Nov 19;23(11):3021. doi: 10.3390/molecules23113021.
1474 MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L.Oncotarget. 2017 Dec 26;9(4):5155-5168. doi: 10.18632/oncotarget.23703. eCollection 2018 Jan 12.
1475 Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.J Nutr Biochem. 2009 Aug;20(8):649-55. doi: 10.1016/j.jnutbio.2008.07.001. Epub 2008 Oct 16.
1476 Pectin Oligosaccharides Ameliorate Colon Cancer by Regulating Oxidative Stress- and Inflammation-Activated Signaling Pathways.Front Immunol. 2018 Jun 27;9:1504. doi: 10.3389/fimmu.2018.01504. eCollection 2018.
1477 Response gene to complement 32 expression in macrophages augments paracrine stimulation-mediated colon cancer progression.Cell Death Dis. 2019 Oct 10;10(10):776. doi: 10.1038/s41419-019-2006-2.
1478 Senescence marker protein 30 protects intestinal epithelial cells against inflammation-induced cell death by enhancing Nrf2 activity.Biochim Biophys Acta Mol Basis Dis. 2018 Dec;1864(12):3668-3678. doi: 10.1016/j.bbadis.2018.09.031. Epub 2018 Sep 26.
1479 Subcellular localization of the Galphai3 protein and G alpha interacting protein, two proteins involved in the control of macroautophagy in human colon cancer HT-29 cells.Biochem J. 1999 Jan 15;337 ( Pt 2)(Pt 2):289-95.
1480 Epidermal growth factor receptor-related protein: a potential therapeutic agent for colorectal cancer.Gastroenterology. 2003 May;124(5):1337-47. doi: 10.1016/s0016-5085(03)00264-6.
1481 The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer.Int J Oncol. 2013 Feb;42(2):676-82. doi: 10.3892/ijo.2012.1746. Epub 2012 Dec 20.
1482 RIN1-Ras-ERK pathway plays an important role in carcinogenesis in colon cancer cell line LoVo.Oncol Res. 2011;19(12):527-34. doi: 10.3727/096504012x13340632812514.
1483 Characterisation of tumour-associated antigens in colon cancer.Cancer Immunol Immunother. 2002 Nov;51(10):574-82. doi: 10.1007/s00262-002-0322-2. Epub 2002 Sep 19.
1484 Increased expression of a Myc target gene Mina53 in human colon cancer.Am J Pathol. 2004 Jan;164(1):205-16. doi: 10.1016/S0002-9440(10)63111-2.
1485 RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression.Theranostics. 2019 Jun 2;9(12):3659-3673. doi: 10.7150/thno.32126. eCollection 2019.
1486 Macrophage inhibitory cytokine-1 (MIC-1) and subsequent urokinase-type plasminogen activator mediate cell death responses by ribotoxic anisomycin in HCT-116 colon cancer cells.Biochem Pharmacol. 2009 Nov 1;78(9):1205-13. doi: 10.1016/j.bcp.2009.06.012. Epub 2009 Jun 18.
1487 Ring Finger Protein 14 is a new regulator of TCF/-catenin-mediated transcription and colon cancer cell survival.EMBO Rep. 2013 Apr;14(4):347-55. doi: 10.1038/embor.2013.19. Epub 2013 Mar 1.
1488 Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation.Front Oncol. 2019 Apr 3;9:224. doi: 10.3389/fonc.2019.00224. eCollection 2019.
1489 Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating -catenin via a novel C-terminal domain.PLoS Biol. 2018 Jan 16;16(1):e2003714. doi: 10.1371/journal.pbio.2003714. eCollection 2018 Jan.
1490 Repression of HIP/RPL29 expression induces differentiation in colon cancer cells.J Cell Physiol. 2006 May;207(2):287-92. doi: 10.1002/jcp.20589.
1491 Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles.Oncotarget. 2016 Nov 29;7(48):79670-79687. doi: 10.18632/oncotarget.13216.
1492 Calcitriol Supplementation Causes Decreases in Tumorigenic Proteins and Different Proteomic and Metabolomic Signatures in Right versus Left-Sided Colon Cancer.Metabolites. 2018 Jan 11;8(1):5. doi: 10.3390/metabo8010005.
1493 Rplp1 bypasses replicative senescence and contributes to transformation.Exp Cell Res. 2009 May 1;315(8):1372-83. doi: 10.1016/j.yexcr.2009.02.007. Epub 2009 Feb 20.
1494 MicroRNA-383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression.Mol Carcinog. 2018 Oct;57(10):1408-1420. doi: 10.1002/mc.22866. Epub 2018 Jul 3.
1495 Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes.Sci Rep. 2016 Nov 28;6:37982. doi: 10.1038/srep37982.
1496 Germline mutation of RPS20, encoding a ribosomal protein, causes predisposition to hereditary nonpolyposis colorectal carcinoma without DNA mismatch repair deficiency. Gastroenterology. 2014 Sep;147(3):595-598.e5. doi: 10.1053/j.gastro.2014.06.009. Epub 2014 Jun 15.
1497 RPS24 knockdown inhibits colorectal cancer cell migration and proliferation in vitro.Gene. 2015 Oct 25;571(2):286-91. doi: 10.1016/j.gene.2015.06.084. Epub 2015 Jul 3.
1498 Ubiquitin fusion proteins are overexpressed in colon cancer but not in gastric cancer.Biochim Biophys Acta. 1995 Dec 12;1272(3):147-53. doi: 10.1016/0925-4439(95)00079-8.
1499 RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.Oncotarget. 2017 Sep 15;8(47):82968-82980. doi: 10.18632/oncotarget.20897. eCollection 2017 Oct 10.
1500 Knockdown of Rhotekin 2 expression suppresses proliferation and induces apoptosis in colon cancer cells.Oncol Lett. 2017 Dec;14(6):8028-8034. doi: 10.3892/ol.2017.7182. Epub 2017 Oct 13.
1501 Cancer as an evolutionary process at the cell level: an epidemiological perspective.Carcinogenesis. 2003 Jan;24(1):1-6. doi: 10.1093/carcin/24.1.1.
1502 Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a.Mol Cancer. 2003 Dec 15;2:42. doi: 10.1186/1476-4598-2-42.
1503 Functional polymorphism in the MicroRNA-367 binding site as a prognostic factor for colonic cancer.Anticancer Res. 2013 Feb;33(2):513-9.
1504 miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4.Oncol Rep. 2015 Oct;34(4):1923-32. doi: 10.3892/or.2015.4168. Epub 2015 Aug 4.
1505 Overexpression of SAMD9 suppresses tumorigenesis and progression during non small cell lung cancer.Biochem Biophys Res Commun. 2014 Nov 7;454(1):157-61. doi: 10.1016/j.bbrc.2014.10.054. Epub 2014 Oct 17.
1506 Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance.Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4723-8. doi: 10.1073/pnas.1519128113. Epub 2016 Apr 11.
1507 SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer.Oncol Rep. 2015 Aug;34(2):727-38. doi: 10.3892/or.2015.4014. Epub 2015 May 28.
1508 Mammaglobin B gene as a novel marker for lymph node micrometastasis in patients with abdominal cancers.Cancer Lett. 2000 Mar 13;150(1):79-84. doi: 10.1016/s0304-3835(99)00378-x.
1509 Secernin-1 contributes to colon cancer progression through enhancing matrix metalloproteinase-2/9 exocytosis.Dis Markers. 2015;2015:230703. doi: 10.1155/2015/230703. Epub 2015 Feb 26.
1510 miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1.Cell Mol Biol Lett. 2017 Jul 17;22:12. doi: 10.1186/s11658-017-0041-5. eCollection 2017.
1511 Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.Invest New Drugs. 2013 Jun;31(3):516-24. doi: 10.1007/s10637-012-9875-x. Epub 2012 Sep 6.
1512 Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1.Biochem Biophys Res Commun. 2011 May 27;409(1):148-53. doi: 10.1016/j.bbrc.2011.04.135. Epub 2011 May 5.
1513 Banxia Xiexin decoction, a traditional Chinese medicine, alleviates colon cancer in nude mice.Ann Transl Med. 2019 Aug;7(16):375. doi: 10.21037/atm.2019.07.26.
1514 Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction.Free Radic Biol Med. 2010 Sep 1;49(5):777-85. doi: 10.1016/j.freeradbiomed.2010.05.035. Epub 2010 Jun 9.
1515 Endogenous axon guiding chemorepulsant semaphorin-3F inhibits the growth and metastasis of colorectal carcinoma.Clin Cancer Res. 2011 May 1;17(9):2702-11. doi: 10.1158/1078-0432.CCR-10-0839. Epub 2011 Feb 24.
1516 A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon Cancer.J Cancer. 2017 Apr 9;8(7):1113-1122. doi: 10.7150/jca.17872. eCollection 2017.
1517 Detection of methylated SEPT9 in plasma is a reliable screening method for both left- and right-sided colon cancers.PLoS One. 2012;7(9):e46000. doi: 10.1371/journal.pone.0046000. Epub 2012 Sep 25.
1518 Heart Failure Stimulates Tumor Growth by Circulating Factors.Circulation. 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816.
1519 Localization of urokinase-type plasminogen activator, plasminogen activator inhibitor-1, 2 and plasminogen in colon cancer.Jpn J Cancer Res. 1995 Jan;86(1):48-56. doi: 10.1111/j.1349-7006.1995.tb02987.x.
1520 Growth-inhibitory effects of TGFL3-SEB chimeric protein on colon cancer cell line.Biomed Pharmacother. 2019 Feb;110:190-196. doi: 10.1016/j.biopha.2018.11.025. Epub 2018 Nov 22.
1521 Epigenetic drift towards histone modifications regulates CAV1 gene expression in colon cancer.Gene. 2016 Apr 25;581(1):75-84. doi: 10.1016/j.gene.2016.01.029. Epub 2016 Jan 19.
1522 PTB-associated splicing factor (PSF) is a PPAR-binding protein and growth regulator of colon cancer cells.PLoS One. 2013;8(3):e58749. doi: 10.1371/journal.pone.0058749. Epub 2013 Mar 13.
1523 INPP4B is an oncogenic regulator in human colon cancer.Oncogene. 2016 Jun 9;35(23):3049-61. doi: 10.1038/onc.2015.361. Epub 2015 Sep 28.
1524 Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer.FASEB J. 2017 Sep;31(9):3816-3830. doi: 10.1096/fj.201601225RR. Epub 2017 May 18.
1525 The 6-integrin-ERK/MAP kinase pathway contributes to chemo resistance in colon cancer.Cancer Lett. 2013 Jan 28;328(2):325-34. doi: 10.1016/j.canlet.2012.10.004. Epub 2012 Oct 13.
1526 Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells.Cells. 2019 Oct 29;8(11):1343. doi: 10.3390/cells8111343.
1527 The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway.Int J Clin Exp Pathol. 2015 Aug 1;8(8):9097-104. eCollection 2015.
1528 SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer.BMC Cancer. 2010 Oct 4;10:525. doi: 10.1186/1471-2407-10-525.
1529 Lack of somatic mutation in the coding sequence of SIAH1 in tumors hemizygous for this candidate tumor suppressor gene.Int J Cancer. 2000 Sep 15;87(6):794-7.
1530 The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid-binding lectin SIGLEC7 on the cell surface.J Biol Chem. 2019 Jul 12;294(28):10833-10845. doi: 10.1074/jbc.RA118.007083. Epub 2019 May 28.
1531 Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors.Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4760-5. doi: 10.1073/pnas.0831000100. Epub 2003 Apr 3.
1532 Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.Apoptosis. 2011 Jan;16(1):35-44. doi: 10.1007/s10495-010-0538-0.
1533 Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer.Mol Carcinog. 2016 Sep;55(9):1355-68. doi: 10.1002/mc.22379. Epub 2015 Aug 21.
1534 Gef gene therapy enhances the therapeutic efficacy of cytotoxics in colon cancer cells.Biomed Pharmacother. 2012 Oct;66(7):563-7. doi: 10.1016/j.biopha.2012.05.004. Epub 2012 Jun 19.
1535 Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells.Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G347-55. doi: 10.1152/ajpgi.00403.2010. Epub 2011 May 19.
1536 DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma.Cancer Sci. 2003 Aug;94(8):692-8. doi: 10.1111/j.1349-7006.2003.tb01504.x.
1537 Insight into the role of PIKK family members and NF-B in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.Cell Death Dis. 2018 Jan 19;9(2):44. doi: 10.1038/s41419-017-0069-5.
1538 Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression.Oncogene. 2016 Feb 4;35(5):549-57. doi: 10.1038/onc.2015.127. Epub 2015 Apr 27.
1539 Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression.Int J Oncol. 2017 Jan;50(1):252-262. doi: 10.3892/ijo.2016.3774. Epub 2016 Nov 18.
1540 SND1 affects proliferation of hepatocellular carcinoma cell line SMMC-7721 by regulating IGFBP3 expression.Anat Rec (Hoboken). 2013 Oct;296(10):1568-75. doi: 10.1002/ar.22737. Epub 2013 Jul 22.
1541 Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation.Br J Pharmacol. 2008 Sep;155(2):198-209. doi: 10.1038/bjp.2008.268. Epub 2008 Jun 30.
1542 Snf1-related kinase inhibits colon cancer cell proliferation through calcyclin-binding protein-dependent reduction of -catenin.FASEB J. 2012 Nov;26(11):4685-95. doi: 10.1096/fj.12-212282. Epub 2012 Aug 8.
1543 Sorting nexin 1 down-regulation promotes colon tumorigenesis.Clin Cancer Res. 2006 Dec 1;12(23):6952-9. doi: 10.1158/1078-0432.CCR-06-0317.
1544 WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14717-22. doi: 10.1073/pnas.95.25.14717.
1545 Alterations in the p53-SOCS2 axis contribute to tumor growth in colon cancer.Exp Mol Med. 2018 Apr 6;50(4):1-10. doi: 10.1038/s12276-017-0001-1.
1546 A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12.EMBO Mol Med. 2014 Jul;6(7):882-901. doi: 10.15252/emmm.201303799.
1547 MicroRNA-645 is an oncogenic regulator in colon cancer.Oncogenesis. 2017 May 15;6(5):e335. doi: 10.1038/oncsis.2017.37.
1548 Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins.Mol Pharmacol. 2005 Aug;68(2):317-29. doi: 10.1124/mol.105.011825. Epub 2005 May 9.
1549 Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.Mol Carcinog. 2016 Dec;55(12):2010-2023. doi: 10.1002/mc.22447. Epub 2015 Dec 14.
1550 Upregulation of spondin-2 predicts poor survival of colorectal carcinoma patients.Oncotarget. 2015 Jun 20;6(17):15095-110. doi: 10.18632/oncotarget.3822.
1551 SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150.Oncogene. 2016 Jun 9;35(23):2991-3003. doi: 10.1038/onc.2015.366. Epub 2015 Oct 12.
1552 Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1.Mol Cancer. 2014 Jan 24;13:11. doi: 10.1186/1476-4598-13-11.
1553 SRPX2 regulates colon cancer cell metabolism by miR-192/215 via PI3K-Akt.Am J Transl Res. 2018 Feb 15;10(2):483-490. eCollection 2018.
1554 Oxidative stress-inducible truncated serine/arginine-rich splicing factor 3 regulates interleukin-8 production in human colon cancer cells.Am J Physiol Cell Physiol. 2014 Feb 1;306(3):C250-62. doi: 10.1152/ajpcell.00091.2013. Epub 2013 Nov 27.
1555 The splicing factor SRSF6 is amplified and is an oncoprotein inlung and colon cancers.J Pathol. 2013 Mar;229(4):630-9. doi: 10.1002/path.4129.
1556 SSBP1 Upregulation In Colorectal Cancer Regulates Mitochondrial Mass.Cancer Manag Res. 2019 Dec 2;11:10093-10106. doi: 10.2147/CMAR.S211292. eCollection 2019.
1557 The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40.Cancer Res. 1996 Oct 15;56(20):4766-72.
1558 Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas.Br J Cancer. 2003 Jun 16;88(12):1909-13. doi: 10.1038/sj.bjc.6600942.
1559 Effect of StarD13 on colorectal cancer proliferation, motility and invasion.Oncol Rep. 2014 Jan;31(1):505-15. doi: 10.3892/or.2013.2861. Epub 2013 Nov 20.
1560 JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841. Epub 2011 Nov 28.
1561 Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23.
1562 Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. doi: 10.1073/pnas.1110428108. Epub 2011 Oct 31.
1563 Aberrant expression of sonic hedgehog pathway in colon cancer and melanosis coli.J Dig Dis. 2013 Aug;14(8):417-24. doi: 10.1111/1751-2980.12060.
1564 Butyrate mediated regulation of RNA binding proteins in the post-transcriptional regulation of inflammatory gene expression.Cell Signal. 2019 Dec;64:109410. doi: 10.1016/j.cellsig.2019.109410. Epub 2019 Sep 2.
1565 Over-expression of small ubiquitin-related modifier-1 and sumoylated p53 in colon cancer.Cell Biochem Biophys. 2013;67(3):1081-7. doi: 10.1007/s12013-013-9612-x.
1566 Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells.Exp Cell Res. 2015 Nov 1;338(2):214-21. doi: 10.1016/j.yexcr.2015.09.016. Epub 2015 Sep 25.
1567 SYNJ2 variant rs9365723 is associated with colorectal cancer risk in Chinese Han population.Int J Biol Markers. 2016 May 28;31(2):e138-43. doi: 10.5301/jbm.5000182.
1568 Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition.Oncoimmunology. 2017 Jan 3;6(2):e1274476. doi: 10.1080/2162402X.2016.1274476. eCollection 2017.
1569 Association between polymorphisms of TAS2R16 and susceptibility to colorectal cancer.BMC Gastroenterol. 2017 Sep 15;17(1):104. doi: 10.1186/s12876-017-0659-9.
1570 Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.Cancer Res. 2009 Apr 15;69(8):3597-604. doi: 10.1158/0008-5472.CAN-08-4368. Epub 2009 Apr 7.
1571 Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.Gastroenterology. 2013 Apr;144(4):799-807.e24. doi: 10.1053/j.gastro.2012.12.020. Epub 2012 Dec 22.
1572 Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.Oncogene. 2010 Dec 9;29(49):6464-74. doi: 10.1038/onc.2010.370. Epub 2010 Aug 30.
1573 Detection of DNA hypermethylation in sera of patients with Crohn's disease.Mol Med Rep. 2014 Feb;9(2):725-9. doi: 10.3892/mmr.2013.1840. Epub 2013 Dec 3.
1574 Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker -catenin: an in silico study.J Biomol Struct Dyn. 2019 Mar;37(4):877-891. doi: 10.1080/07391102.2018.1442250. Epub 2018 Mar 12.
1575 A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer.Oncogene. 2009 Nov 26;28(47):4133-46. doi: 10.1038/onc.2009.271. Epub 2009 Sep 14.
1576 Prevention of Wogonin on Colorectal Cancer Tumorigenesis by Regulating p53 Nuclear Translocation.Front Pharmacol. 2018 Nov 23;9:1356. doi: 10.3389/fphar.2018.01356. eCollection 2018.
1577 C8orf4 is a transforming growth factor B induced transcript downregulated in metastatic colon cancer.Int J Cancer. 2004 Aug 10;111(1):72-5. doi: 10.1002/ijc.20235.
1578 Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.Med Sci Monit. 2017 Jan 26;23:452-461. doi: 10.12659/msm.899595.
1579 Serological identification of Tektin5 as a cancer/testis antigen and its immunogenicity.BMC Cancer. 2012 Nov 14;12:520. doi: 10.1186/1471-2407-12-520.
1580 Association between colonic screening, subject characteristics, and stage of colorectal cancer.Am J Gastroenterol. 2005 Nov;100(11):2531-9. doi: 10.1111/j.1572-0241.2005.00319.x.
1581 TET1 suppresses colon cancer proliferation by impairing -catenin signal pathway.J Cell Biochem. 2019 Aug;120(8):12559-12565. doi: 10.1002/jcb.28522. Epub 2019 Mar 1.
1582 The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer.Cell Death Differ. 2019 Oct;26(10):1955-1969. doi: 10.1038/s41418-018-0265-6. Epub 2019 Jan 18.
1583 TFF2-CXCR4 Axis Is Associated with BRAF V600E Colon Cancer.Cancer Prev Res (Phila). 2015 Jul;8(7):614-9. doi: 10.1158/1940-6207.CAPR-14-0444. Epub 2015 Apr 21.
1584 Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III.J Biol Chem. 2001 Jan 12;276(2):1555-63. doi: 10.1074/jbc.M004553200.
1585 Human thrombospondin 2 inhibits proliferation of microvascular endothelial cells.Int J Oncol. 2002 Feb;20(2):339-42.
1586 Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.Mol Oncol. 2015 Jan;9(1):167-78. doi: 10.1016/j.molonc.2014.07.017. Epub 2014 Aug 20.
1587 Ca(2+)/calmodulin-dependent protein kinase II regulates colon cancer proliferation and migration via ERK1/2 and p38 pathways.World J Gastroenterol. 2017 Sep 7;23(33):6111-6118. doi: 10.3748/wjg.v23.i33.6111.
1588 Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer.Cancer Sci. 2017 Apr;108(4):744-752. doi: 10.1111/cas.13187. Epub 2017 Apr 12.
1589 MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer.Int J Oncol. 2016 May;48(5):2135-43. doi: 10.3892/ijo.2016.3430. Epub 2016 Mar 9.
1590 The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer.Cancer Biol Ther. 2014 Sep;15(9):1198-207. doi: 10.4161/cbt.29500. Epub 2014 Jun 11.
1591 Identification of specific modules and significant genes associated with colon cancer by weighted gene coexpression network analysis.Mol Med Rep. 2019 Jul;20(1):693-700. doi: 10.3892/mmr.2019.10295. Epub 2019 May 24.
1592 Tumor suppressor gene NGX6 induces changes in protein expression profiles in colon cancer HT-29 cells.Acta Biochim Biophys Sin (Shanghai). 2012 Jul;44(7):584-90. doi: 10.1093/abbs/gms042. Epub 2012 May 30.
1593 Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy.Oncogenesis. 2017 Sep 18;6(9):e378. doi: 10.1038/oncsis.2017.77.
1594 TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability.Cancer Biol Ther. 2014 Mar 1;15(3):297-304. doi: 10.4161/cbt.27308. Epub 2013 Dec 12.
1595 SCC-S2 is overexpressed in colon cancers and regulates cell proliferation.Tumour Biol. 2012 Dec;33(6):2099-106. doi: 10.1007/s13277-012-0469-1. Epub 2012 Aug 12.
1596 A novel inflammatory regulator TIPE2 inhibits TLR4-mediated development of colon cancer via caspase-8.Cancer Biomark. 2014;14(4):233-40. doi: 10.3233/CBM-140402.
1597 Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism.Biochem Biophys Res Commun. 2010 Jan 8;391(2):1274-9. doi: 10.1016/j.bbrc.2009.12.058. Epub 2009 Dec 17.
1598 DcR3 regulates the growth and metastatic potential of SW480 colon cancer cells.Oncol Rep. 2013 Dec;30(6):2741-8. doi: 10.3892/or.2013.2769. Epub 2013 Oct 1.
1599 The study on specific umbilical blood Dc vaccine for Beige nude mice loaded human colorectal carcinoma to induce anti-tumor immunity.Eur Rev Med Pharmacol Sci. 2017 May;21(10):2364-2371.
1600 High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer.Mol Cancer. 2018 Nov 17;17(1):159. doi: 10.1186/s12943-018-0907-9.
1601 Targeting PRPK Function Blocks Colon Cancer Metastasis.Mol Cancer Ther. 2018 May;17(5):1101-1113. doi: 10.1158/1535-7163.MCT-17-0628. Epub 2018 Feb 26.
1602 Epigenetic silencing of TPM2 contributes to colorectal cancer progression upon RhoA activation.Tumour Biol. 2016 Sep;37(9):12477-12483. doi: 10.1007/s13277-016-5103-1. Epub 2016 Jun 23.
1603 The clinical significance and biological function of tropomyosin 4 in colon cancer.Biomed Pharmacother. 2018 May;101:1-7. doi: 10.1016/j.biopha.2018.01.166. Epub 2018 Feb 22.
1604 Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway.Oncogene. 2004 Mar 11;23(10):1885-95. doi: 10.1038/sj.onc.1207312.
1605 Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway.J Biol Chem. 2012 Jul 27;287(31):25881-92. doi: 10.1074/jbc.M112.359521. Epub 2012 Jun 8.
1606 An acellular tissue matrix-based drug carriers with dual chemo-agents for colon cancer growth suppression.Biomed Pharmacother. 2019 Sep;117:109048. doi: 10.1016/j.biopha.2019.109048. Epub 2019 Jun 8.
1607 TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer.Oncotarget. 2016 Dec 27;7(52):86755-86765. doi: 10.18632/oncotarget.13550.
1608 Role of the focal adhesion protein TRIM15 in colon cancer development.Biochim Biophys Acta. 2015 Feb;1853(2):409-21. doi: 10.1016/j.bbamcr.2014.11.007. Epub 2014 Nov 15.
1609 Increased expression of TRPS1 affects tumor progression and correlates with patients' prognosis of colon cancer.Biomed Res Int. 2013;2013:454085. doi: 10.1155/2013/454085. Epub 2013 May 26.
1610 TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.Blood. 2018 Jun 21;131(25):2789-2802. doi: 10.1182/blood-2017-09-806679. Epub 2018 Apr 13.
1611 Over-expression of the testis-specific gene TSGA10 in cancers and its immunogenicity.Microbiol Immunol. 2004;48(4):339-45. doi: 10.1111/j.1348-0421.2004.tb03515.x.
1612 Discovery of a diagnostic biomarker for colon cancer through proteomic profiling of small extracellular vesicles.BMC Cancer. 2018 Nov 1;18(1):1058. doi: 10.1186/s12885-018-4952-y.
1613 Ultrasensitive NIR-SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation.Adv Healthc Mater. 2018 Feb;7(4). doi: 10.1002/adhm.201700870. Epub 2017 Dec 1.
1614 miR663aTTC22V1 axis inhibits colon cancer metastasis.Oncol Rep. 2019 Mar;41(3):1718-1728. doi: 10.3892/or.2019.6969. Epub 2019 Jan 16.
1615 ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells.Tumour Biol. 2015 Nov;36(11):9005-13. doi: 10.1007/s13277-015-3664-z. Epub 2015 Jun 18.
1616 Up-regulated expression of l-caldesmon associated with malignancy of colorectal cancer.BMC Cancer. 2012 Dec 17;12:601. doi: 10.1186/1471-2407-12-601.
1617 A functional variant of IC53 correlates with the late onset of colorectal cancer.Mol Med. 2011;17(7-8):607-18. doi: 10.2119/molmed.2010.00192. Epub 2011 Mar 2.
1618 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.J Clin Invest. 2014 Dec;124(12):5398-410. doi: 10.1172/JCI76614. Epub 2014 Oct 27.
1619 Cysteine-Rich Intestinal Protein 1 Silencing Inhibits Migration and Invasion in Human Colorectal Cancer.Cell Physiol Biochem. 2017;44(3):897-906. doi: 10.1159/000485357. Epub 2017 Nov 24.
1620 Differential roles of EPS8 in carcinogenesis: loss of protein expression in a subset of colorectal carcinoma and adenoma.World J Gastroenterol. 2012 Aug 7;18(29):3896-903. doi: 10.3748/wjg.v18.i29.3896.
1621 DNA methylation biomarker candidates for early detection of colon cancer.Tumour Biol. 2012 Apr;33(2):363-72. doi: 10.1007/s13277-011-0302-2. Epub 2012 Jan 12.
1622 FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.Oncotarget. 2017 Jan 17;8(3):5048-5056. doi: 10.18632/oncotarget.13790.
1623 Hypermethylation of the GATA gene family in esophageal cancer.Int J Cancer. 2006 Nov 1;119(9):2078-83. doi: 10.1002/ijc.22092.
1624 The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.J Biol Chem. 2013 Dec 13;288(50):35637-50. doi: 10.1074/jbc.M113.472076. Epub 2013 Oct 25.
1625 Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.PLoS One. 2013 Sep 9;8(9):e73593. doi: 10.1371/journal.pone.0073593. eCollection 2013.
1626 A core matrisome gene signature predicts cancer outcome.Br J Cancer. 2018 Feb 6;118(3):435-440. doi: 10.1038/bjc.2017.458. Epub 2018 Jan 23.
1627 Brush border myosin Ia has tumor suppressor activity in the intestine.Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. doi: 10.1073/pnas.1108411109. Epub 2012 Jan 18.
1628 The effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide.J Control Release. 2017 Jul 10;257:102-117. doi: 10.1016/j.jconrel.2016.06.038. Epub 2016 Jun 30.
1629 3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans.Cancer Res. 2012 Mar 15;72(6):1467-77. doi: 10.1158/0008-5472.CAN-11-3073. Epub 2012 Jan 26.
1630 Polymorphisms of the apoptosis-associated gene DP1L1 (deleted in polyposis 1-like 1) in colon cancer and inflammatory bowel disease.J Cancer Res Clin Oncol. 2010 Jun;136(6):795-802. doi: 10.1007/s00432-009-0719-9. Epub 2009 Nov 19.
1631 Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity.Am J Pathol. 2011 Mar;178(3):1009-20. doi: 10.1016/j.ajpath.2010.11.047.
1632 Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.Biochem Pharmacol. 2012 Apr 1;83(7):849-57. doi: 10.1016/j.bcp.2012.01.007. Epub 2012 Jan 13.
1633 Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.Mol Carcinog. 2012 Sep;51(9):746-53. doi: 10.1002/mc.20843. Epub 2011 Aug 30.
1634 Design, synthesis and evaluation of novel sulfonamides as potential anticancer agents.Comput Biol Chem. 2018 Jun;74:294-303. doi: 10.1016/j.compbiolchem.2018.04.006. Epub 2018 Apr 10.
1635 Ets1 and heat shock factor 1 regulate transcription of the Transformer 2 gene in human colon cancer cells.J Gastroenterol. 2013 Nov;48(11):1222-33. doi: 10.1007/s00535-012-0745-2. Epub 2013 Jan 30.