Details of Disease

General Information of Disease (ID: DIS5PYL0)

• Disease Name: Colorectal carcinoma
• Synonyms: colorectal (colon or rectal) cancer; cancer of large intestine; cancer of large bowel; large intestine cancer; cancer of the large bowel; colorectal cancer; large bowel cancer; cancer of the large intestine; large intestine carcinoma; carcinoma of the large intestine; carcinoma of colorectum; large bowel carcinoma; colorectum carcinoma; carcinoma of large intestine; carcinoma of large bowel; colorectal carcinoma; carcinoma of the large bowel; CRC
• Definition: A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas.
• Disease Hierarchy:
  DISFC6MM: Digestive system carcinoma
  DISNH7P9: Colorectal cancer
  DISH9F1N: Carcinoma
  DIS5PYL0: Colorectal carcinoma
• Disease Identifiers:
  MONDO ID: MONDO_0024331
  MESH ID: D015179
  UMLS CUI: C0009402
  OMIM ID: 114500
  MedGen ID: 3170

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 6 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Bevacizumab	DMSD1UN	Approved	Monoclonal antibody	[1]
Doxycycline	DM7ICNU	Approved	Small molecular drug	[2]
Folic Acid	DMEMBJC	Approved	Small molecular drug	[3]
Levoleucovorin	DMH5LME	Approved	Small molecular drug	[4]
Metformin	DM89QE1	Approved	Small molecular drug	[5]
Oxaliplatin	DMQNWRD	Approved	Small molecular drug	[6]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1207 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ABCC2	TTFLHJV	Limited	Altered Expression	[7]
ACO2	TTMTF2P	Limited	Biomarker	[8]
ADGRL1	TTM5OJN	Limited	Biomarker	[9]
ADK	TTL732K	Limited	Altered Expression	[10]
ADM	TTV14YH	Limited	Altered Expression	[11]
ADRA1B	TTBRKXS	Limited	Posttranslational Modification	[12]
ADRB3	TTMXGCW	Limited	Genetic Variation	[13]
AFP	TTCFEA1	Limited	Biomarker	[14]
AMACR	TTLN1AP	Limited	Biomarker	[15]
ANPEP	TTPHMWB	Limited	Altered Expression	[16]
ATR	TT8ZYBQ	Limited	Genetic Variation	[17]
AURKC	TTLYXIT	Limited	Altered Expression	[18]
BAK1	TTFM7V0	Limited	Biomarker	[19]
BCL2L1	TTRE6AX	Limited	Biomarker	[20]
BMP7	TTKOBRA	Limited	Biomarker	[21]
BRCA2	TTUARD6	Limited	Biomarker	[17]
BRD7	TT07ZS1	Limited	Biomarker	[22]
BTK	TTGM6VW	Limited	Biomarker	[23]
CASP5	TTWR48J	Limited	Genetic Variation	[24]
CASP7	TTM7Y45	Limited	Biomarker	[25]
CBR1	TTVG0SN	Limited	Biomarker	[26]
CCL3	TT8I4WB	Limited	Biomarker	[27]
CCR7	TT2GIDQ	Limited	Altered Expression	[28]
CD27	TTDO1MV	Limited	Biomarker	[29]
CD33	TTJVYO3	Limited	Biomarker	[30]
CD59	TTBGTEJ	Limited	Biomarker	[31]
CD70	TTNCIE0	Limited	Altered Expression	[29]
CDA	TTQ12RK	Limited	Biomarker	[32]
CDC37	TT5SOEU	Limited	Biomarker	[33]
CDK6	TTO0FDJ	Limited	Altered Expression	[34]
CDK7	TTQYF7G	Limited	Altered Expression	[35]
CDKL1	TTBTI6P	Limited	Altered Expression	[36]
CEACAM6	TTIGH2W	Limited	Biomarker	[37]
CEBPB	TTUI35N	Limited	Altered Expression	[38]
CMA1	TT8VUE0	Limited	Biomarker	[39]
CRY1	TT5MLZR	Limited	Altered Expression	[40]
CRYAB	TT7RUHB	Limited	Genetic Variation	[41]
CSNK1E	TTA8PLI	Limited	Biomarker	[42]
CSNK2A1	TTER6YH	Limited	Genetic Variation	[43]
CTAG1A	TTE5ITK	Limited	Altered Expression	[44]
CTSK	TTDZN01	Limited	Biomarker	[45]
CXCL13	TT0NIZ1	Limited	Genetic Variation	[46]
CXCR4	TTBID49	Limited	Biomarker	[47]
CYP2C19	TTZ58XG	Limited	Altered Expression	[48]
CYP3A5	TTHS0OK	Limited	Altered Expression	[49]
DDR2	TTU98HG	Limited	Altered Expression	[50]
DKK2	TTST5KX	Limited	Altered Expression	[51]
DRD2	TTEX248	Limited	Genetic Variation	[52]
DUSP10	TTF3RJ0	Limited	Altered Expression	[53]
EBI3	TTJF68X	Limited	Biomarker	[54]
EBP	TT4VQZX	Limited	Biomarker	[55]
EGFL6	TTXJGAR	Limited	Biomarker	[56]
ELAVL1	TTPC9D0	Limited	Altered Expression	[57]
ENAH	TTY36UA	Limited	Genetic Variation	[58]
ENTPD1	TTYM8DJ	Limited	Biomarker	[59]
EPHA4	TTG84D3	Limited	Altered Expression	[60]
EPHB2	TTKPV6O	Limited	Biomarker	[61]
ESRRA	TTPNQAC	Limited	Altered Expression	[62]
FABP4	TTHWMFZ	Limited	Altered Expression	[63]
FAM83D	TTFIW7J	Limited	Biomarker	[64]
FANCA	TTV5HJS	Limited	Biomarker	[8]
FAT1	TTGUJYV	Limited	Biomarker	[65]
FCGR2B	TT5RWKQ	Limited	Biomarker	[66]
FGFBP1	TTV1YFT	Limited	Altered Expression	[67]
FN3K	TTP6W8J	Limited	Altered Expression	[68]
FUS	TTKGYZ9	Limited	Biomarker	[69]
GAPDH	TTUGSWA	Limited	Biomarker	[70]
GEM	TTAZF9M	Limited	Biomarker	[71]
GHR	TTHJWYD	Limited	Altered Expression	[72]
GIP	TT40HS5	Limited	Biomarker	[73]
GLI1	TTJOMH6	Limited	Biomarker	[74]
GPBAR1	TTSDVTR	Limited	Biomarker	[75]
GRIN2B	TTN9D8E	Limited	Biomarker	[76]
GRM2	TTXJ47W	Limited	Biomarker	[77]
GRPR	TTC1MVT	Limited	Biomarker	[78]
GSTO1	TTWO3SH	Limited	Biomarker	[79]
HDAC3	TT4YWTO	Limited	Biomarker	[80]
HK2	TTK02H8	Limited	Biomarker	[81]
HNF1A	TT01M3K	Limited	Altered Expression	[82]
HSD17B1	TTIWB6L	Limited	Biomarker	[83]
HSPA9	TTMTPG3	Limited	Altered Expression	[84]
ICA1	TTMX06B	Limited	Genetic Variation	[85]
ID1	TTBXVDE	Limited	Altered Expression	[86]
IGFBP5	TTDWEA8	Limited	Altered Expression	[87]
IL11	TTGUYTR	Limited	Biomarker	[88]
IL1RL1	TT4GZA4	Limited	Biomarker	[89]
IL24	TT1EPXZ	Limited	Biomarker	[90]
IL2RB	TT9721Y	Limited	Genetic Variation	[91]
INPP1	TTW0PHM	Limited	Genetic Variation	[92]
ITGAV	TTT1R2L	Limited	Biomarker	[93]
KCNK9	TTL4FMB	Limited	Biomarker	[94]
KIF20B	TTQECT2	Limited	Biomarker	[95]
KISS1R	TT3KBZY	Limited	Biomarker	[96]
KLK3	TTS78AZ	Limited	Genetic Variation	[97]
KLK4	TT4319X	Limited	Altered Expression	[98]
KLK5	TTULSEW	Limited	Altered Expression	[99]
LCK	TT860QF	Limited	Altered Expression	[100]
LGALS1	TTO3NYT	Limited	Biomarker	[101]
LPA	TTU9LGY	Limited	Biomarker	[102]
LPAR2	TTB7Y8I	Limited	Biomarker	[103]
LRP5	TT7VMG4	Limited	Altered Expression	[104]
LRRC32	TT0FAYT	Limited	Biomarker	[105]
LYN	TT1RWNJ	Limited	Altered Expression	[106]
MAGEC2	TTKGUEB	Limited	Biomarker	[107]
MAP3K20	TTTUZ3O	Limited	Biomarker	[108]
MAP3K8	TTGECUM	Limited	Altered Expression	[109]
MAPKAPK2	TTMUG9D	Limited	Biomarker	[110]
MDK	TTV8UE7	Limited	Altered Expression	[111]
MDM4	TT9OUDQ	Limited	Altered Expression	[112]
METAP2	TTZL0OI	Limited	Biomarker	[30]
MKI67	TTB4UNG	Limited	Altered Expression	[113]
MMP16	TTNP4CU	Limited	Altered Expression	[114]
MMP21	TTYRF5E	Limited	Biomarker	[115]
MSI1	TTSM4BA	Limited	Biomarker	[116]
MTTP	TTUS1RD	Limited	Genetic Variation	[117]
MUC17	TTVO0JU	Limited	Altered Expression	[118]
MUC5AC	TTEL90S	Limited	Biomarker	[119]
MYBPC3	TT9WOBN	Limited	Biomarker	[120]
MYLK2	TTHLGB2	Limited	Genetic Variation	[121]
NCAM1	TTVXPHT	Limited	Biomarker	[122]
NFKBIA	TTSHAEB	Limited	Genetic Variation	[123]
NOTCH3	TTVX7IA	Limited	Biomarker	[124]
NPY4R	TTW4N16	Limited	Biomarker	[125]
NR4A1	TTMXE2Q	Limited	Altered Expression	[126]
NR4A2	TT9HKN3	Limited	Altered Expression	[127]
NRP1	TTIPJCB	Limited	Genetic Variation	[128]
NT5E	TTK0O6Y	Limited	Biomarker	[129]
OPA1	TTTU49Q	Limited	Genetic Variation	[130]
ORAI1	TTE76YK	Limited	Biomarker	[131]
P2RY13	TT1FE3L	Limited	Genetic Variation	[132]
PAK4	TT7Y3BZ	Limited	Biomarker	[133]
PBK	TTMY6BZ	Limited	Altered Expression	[134]
PDCD1	TTNBFWK	Limited	Biomarker	[135]
PDE4A	TTZ97H5	Limited	Biomarker	[136]
PDE4B	TTVIAT9	Limited	Biomarker	[137]
PDE4D	TTSKMI8	Limited	Biomarker	[136]
PDE5A	TTJ0IQB	Limited	Biomarker	[138]
PDX1	TT8SGZK	Limited	Biomarker	[139]
PF4	TTSG7Q5	Limited	Biomarker	[140]
PLAUR	TTNOSTX	Limited	Biomarker	[141]
PLK4	TTGPNZQ	Limited	Biomarker	[142]
PLOD1	TTEKJP3	Limited	Biomarker	[143]
POLB	TTA0XPV	Limited	Biomarker	[144]
PRKCZ	TTBSN0L	Limited	Altered Expression	[145]
PRMT5	TTR1D7X	Limited	Biomarker	[146]
PSEN2	TTWN3F4	Limited	Biomarker	[147]
PTGES	TTYLQ8V	Limited	Biomarker	[148]
PTGES2	TTWU04I	Limited	Biomarker	[149]
PTGIS	TTLXKZR	Limited	Posttranslational Modification	[150]
PTPN13	TT405FP	Limited	Genetic Variation	[151]
PTPRC	TTUS45N	Limited	Biomarker	[152]
RACK1	TTJ10AL	Limited	Altered Expression	[153]
RARA	TTW38KT	Limited	Altered Expression	[154]
RBP4	TT0C8BY	Limited	Biomarker	[155]
RECK	TTRZBW7	Limited	Biomarker	[156]
RGS16	TTFRES8	Limited	Biomarker	[157]
RGS2	TTKB7T3	Limited	Altered Expression	[158]
RICTOR	TT143WL	Limited	Altered Expression	[159]
RIPK1	TTVJHX8	Limited	Biomarker	[160]
RNASEL	TT7V0K4	Limited	Genetic Variation	[161]
ROBO4	TT3S9TY	Limited	Altered Expression	[162]
ROR1	TTDEJAU	Limited	Biomarker	[163]
RORC	TTGV6LY	Limited	Biomarker	[164]
RPH3A	TT9L4J8	Limited	Genetic Variation	[165]
RPS6KB1	TTG0U4H	Limited	Altered Expression	[166]
SDHD	TTVH9W8	Limited	Altered Expression	[167]
SELP	TTE5VG0	Limited	Biomarker	[168]
SIGMAR1	TT5TPI6	Limited	Biomarker	[131]
SLC10A2	TTPI1M5	Limited	Genetic Variation	[169]
SLC14A1	TTWVJU1	Limited	Genetic Variation	[170]
SLC16A1	TTN1J82	Limited	Biomarker	[39]
SLC6A14	TTB6H2S	Limited	Biomarker	[171]
SLCO4A1	TTV1YIE	Limited	Biomarker	[172]
SREBF2	TTRQ4AP	Limited	Genetic Variation	[173]
SSRP1	TTETDKQ	Limited	Altered Expression	[174]
ST14	TTPRO7W	Limited	Genetic Variation	[175]
STAT1	TTN7R6K	Limited	Biomarker	[176]
SUV39H1	TTUWQTK	Limited	Altered Expression	[177]
TAOK1	TTQY9DH	Limited	Altered Expression	[178]
TEK	TT9VGXW	Limited	Biomarker	[179]
TENT4A	TT0XZ4Q	Limited	Biomarker	[180]
TERF1	TT1Y6J2	Limited	Biomarker	[181]
TFPI	TT068JH	Limited	Biomarker	[182]
TFRC	TT8MG4S	Limited	Altered Expression	[183]
TGFB2	TTI0KH6	Limited	Biomarker	[184]
TLR3	TTD24Y0	Limited	Biomarker	[185]
TLR7	TTRJ1K4	Limited	Biomarker	[186]
TLR8	TT8CWFK	Limited	Altered Expression	[187]
TMEM97	TT9NXW4	Limited	Biomarker	[188]
TNFRSF11B	TT2CJ75	Limited	Biomarker	[189]
TNKS	TTVUSO7	Limited	Biomarker	[190]
TNNI3	TTNLDK6	Limited	Biomarker	[191]
TRPM8	TTXDKTO	Limited	Altered Expression	[192]
TUSC2	TTJ8O14	Limited	Genetic Variation	[193]
UCHL1	TTX9IFP	Limited	Biomarker	[194]
ZNF217	TTY3BRA	Limited	Genetic Variation	[195]
APOBEC3G	TTP96KH	Disputed	Biomarker	[196]
EIF4EBP2	TTNBTCW	Disputed	Biomarker	[197]
GSTA2	TTNLFBE	Disputed	Biomarker	[198]
HSD17B4	TTL1WGS	Disputed	Biomarker	[199]
MASP2	TTR01E9	Disputed	Genetic Variation	[200]
RHOB	TT6LPFO	Disputed	Altered Expression	[201]
ADAMTS4	TTYG6BU	moderate	Altered Expression	[202]
ADRA1A	TTNGILX	moderate	Biomarker	[103]
ADRA2B	TTWM4TY	moderate	Biomarker	[103]
AIMP2	TTXWHGF	moderate	Biomarker	[203]
APOC3	TTXOZQ1	moderate	Biomarker	[204]
AXL	TTZPY6J	moderate	Altered Expression	[205]
BCL11A	TTR61MW	moderate	Biomarker	[206]
BIRC2	TTQ5LRD	moderate	Biomarker	[207]
BRS3	TTKYEPM	moderate	Biomarker	[103]
BUB1	TT78309	moderate	Biomarker	[208]
CACNA1F	TTJ0SO4	moderate	Biomarker	[209]
CCL11	TTCF05Y	moderate	Altered Expression	[210]
CCL22	TTBTWI1	moderate	Altered Expression	[211]
CD274	TT8ZLTI	moderate	Biomarker	[212]
CD276	TT6CQUM	moderate	Altered Expression	[213]
CDC25C	TTESBNC	moderate	Biomarker	[214]
CDH3	TTARMD9	moderate	Genetic Variation	[215]
CLDN4	TTMTS9H	moderate	Altered Expression	[216]
CLU	TTRL76H	moderate	Biomarker	[217]
COL1A2	TTUABC1	moderate	Biomarker	[218]
COL6A3	TT5WCAH	moderate	Biomarker	[219]
CR1	TTEA8OW	moderate	Altered Expression	[220]
CRHR2	TTIY658	moderate	Biomarker	[221]
CRK	TTFEUYR	moderate	Biomarker	[203]
CTSC	TT4H0V2	moderate	Biomarker	[222]
CXCL9	TTWE5PB	moderate	Altered Expression	[223]
CXCR1	TTMWT8Z	moderate	Altered Expression	[224]
CXCR6	TT2BVUA	moderate	Biomarker	[103]
E2F1	TTASI04	moderate	Altered Expression	[225]
EHMT2	TTS6RZT	moderate	Altered Expression	[226]
EIF2AK3	TT79U1M	moderate	Biomarker	[227]
EIF2AK4	TT9U4EP	moderate	Biomarker	[228]
EPHB1	TT8MDAC	moderate	Genetic Variation	[229]
FCGR2A	TTXT21W	moderate	Biomarker	[66]
FCGRT	TTKLPHO	moderate	Altered Expression	[230]
FGF21	TTQ916P	moderate	Biomarker	[231]
FGFR2	TTGJVQM	moderate	Altered Expression	[232]
FLT1	TT1VAUK	moderate	Biomarker	[233]
FLT3	TTGJCWZ	moderate	Biomarker	[234]
FOLR2	TTT54CI	moderate	Biomarker	[235]
FOSL2	TT689IR	moderate	Biomarker	[236]
GFRA3	TT63XRS	moderate	Biomarker	[237]
GHSR	TTWDC17	moderate	Posttranslational Modification	[238]
GLP1R	TTVIMDE	moderate	Biomarker	[239]
GUSB	TTHS7CM	moderate	Biomarker	[240]
HMGB1	TTWQYB7	moderate	Biomarker	[241]
HSP90B1	TTFPKXQ	moderate	Biomarker	[242]
HSPB3	TTLH8WG	moderate	Altered Expression	[243]
HTRA1	TT8POQR	moderate	Biomarker	[244]
IKBKB	TTJ3E9X	moderate	Altered Expression	[245]
IL32	TTD4G7L	moderate	Altered Expression	[246]
IL9	TT0JTFD	moderate	Genetic Variation	[247]
IRF3	TTYR7OH	moderate	Biomarker	[248]
ITGAE	TTH0Z37	moderate	Biomarker	[249]
ITGAL	TT48WR6	moderate	Genetic Variation	[250]
ITK	TT3C80U	moderate	Altered Expression	[251]
JAG2	TTOJY1B	moderate	Altered Expression	[252]
KCNMA1	TTE87WJ	moderate	Altered Expression	[253]
KDM4C	TTV8CRH	moderate	Altered Expression	[254]
KIR2DS1	TTVWAGF	moderate	Genetic Variation	[255]
KLRC1	TTC4IMS	moderate	Biomarker	[256]
KSR1	TTHL1TV	moderate	Biomarker	[257]
LIMK1	TTWL9TY	moderate	Altered Expression	[258]
LIMK2	TTASMD8	moderate	Altered Expression	[258]
LPAR1	TTQ6S1K	moderate	Biomarker	[259]
LRP1	TTF2V7I	moderate	Genetic Variation	[215]
MAP3K11	TTETX6Q	moderate	Altered Expression	[260]
MAP3K21	TTSW9YL	moderate	Biomarker	[261]
MAP4K4	TT6NI13	moderate	Altered Expression	[262]
MAPK14	TTQBR95	moderate	Biomarker	[203]
MME	TT5TKPM	moderate	Biomarker	[119]
MMP2	TTLM12X	moderate	Biomarker	[263]
MMP8	TTGA1IV	moderate	Biomarker	[264]
MVD	TTE5J6X	moderate	Biomarker	[265]
NCL	TTK1V5Q	moderate	Biomarker	[266]
NCOA4	TT8OY02	moderate	Genetic Variation	[267]
NLRC5	TTWZC78	moderate	Genetic Variation	[268]
NPR3	TTWVLS6	moderate	Biomarker	[269]
NR0B1	TTTK36V	moderate	Biomarker	[270]
NR5A2	TTAU3SY	moderate	Biomarker	[271]
NUAK1	TT65FL0	moderate	Biomarker	[272]
OPRD1	TT27RFC	moderate	Biomarker	[273]
PAWR	TT3I4WV	moderate	Biomarker	[274]
PGC	TT7K6AD	moderate	Genetic Variation	[275]
PIN1	TTJNTSI	moderate	Altered Expression	[276]
PKMYT1	TTB4PAZ	moderate	Biomarker	[277]
PLXDC1	TTPSK7A	moderate	Biomarker	[278]
PPARA	TTJ584C	moderate	Altered Expression	[279]
PRMT1	TTVOJAI	moderate	Biomarker	[280]
PTGS1	TT8NGED	moderate	Altered Expression	[281]
PTK2B	TTTEFBV	moderate	Biomarker	[282]
PTN	TTA9EJK	moderate	Altered Expression	[283]
REG4	TTVZEHU	moderate	Biomarker	[284]
RGS6	TTJ96M8	moderate	Biomarker	[285]
RNF6	TT4S09X	moderate	Altered Expression	[286]
RORA	TT1TYN7	moderate	Genetic Variation	[287]
RRM1	TTWP0NS	moderate	Altered Expression	[288]
SAA1	TTY0DN9	moderate	Altered Expression	[289]
SEPTIN6	TTAGE7U	moderate	Biomarker	[290]
SETD7	TTJ0FSU	moderate	Altered Expression	[291]
SLC22A3	TTG2UMS	moderate	Altered Expression	[251]
SLC2A4	TTP6MT5	moderate	Biomarker	[292]
SLC7A5	TTPH2JB	moderate	Biomarker	[293]
SLCO2A1	TTKVTQO	moderate	Genetic Variation	[294]
SPHK2	TTCN0M9	moderate	Biomarker	[295]
SSTR2	TTZ6T9E	moderate	Biomarker	[296]
SSTR4	TTAE1BR	moderate	Biomarker	[103]
STK33	TTP34DQ	moderate	Altered Expression	[297]
TDP1	TT64IHJ	moderate	Altered Expression	[298]
THPO	TTCG5PE	moderate	Biomarker	[299]
TIGIT	TTWNL74	moderate	Altered Expression	[300]
TRPM6	TTV76RD	moderate	Altered Expression	[301]
TSPO	TTPTXIN	moderate	Biomarker	[302]
UCP1	TTI12YJ	moderate	Biomarker	[303]
VSIR	TT51SK8	moderate	Altered Expression	[304]
ABCA1	TTJW1GN	Strong	Biomarker	[305]
ABCA4	TTLB52K	Strong	Biomarker	[306]
ABCB4	TTJUXV6	Strong	Biomarker	[307]
ABCC1	TTOI92F	Strong	Altered Expression	[112]
ABCC4	TTUEAFL	Strong	Genetic Variation	[308]
ACAA2	TTM3F49	Strong	Altered Expression	[309]
ACACB	TTY84UG	Strong	Biomarker	[310]
ACKR3	TTRQJTC	Strong	Biomarker	[311]
ACLY	TT0Z6Y2	Strong	Genetic Variation	[312]
ACR	TTAHE2N	Strong	Biomarker	[313]
ACVR1	TTJNBQA	Strong	Biomarker	[314]
ACVR2A	TTX2DRI	Strong	Genetic Variation	[315]
ACVRL1	TTGYPTC	Strong	Altered Expression	[316]
ADAM10	TTVXEGU	Strong	Altered Expression	[317]
ADAM17	TT6AZXG	Strong	Biomarker	[318]
ADAM8	TTQWYMD	Strong	Biomarker	[319]
ADAMTS1	TTS2TEI	Strong	Genetic Variation	[320]
ADAMTS5	TTXSU2Y	Strong	Biomarker	[321]
ADCY1	TTV1ZSQ	Strong	Genetic Variation	[322]
ADORA1	TTK25J1	Strong	Biomarker	[323]
ADRB2	TTG8ZWP	Strong	Biomarker	[324]
AGR2	TT9K86S	Strong	Biomarker	[325]
AGRP	TT4DE1O	Strong	Biomarker	[326]
AHCY	TTE2KUJ	Strong	Altered Expression	[327]
AKR1B1	TTFBNVI	Strong	Biomarker	[328]
AKT3	TTO6SGY	Strong	Altered Expression	[329]
ALCAM	TT2AFT6	Strong	Altered Expression	[330]
ALK	TTPMQSO	Strong	Biomarker	[331]
ALKBH5	TTOHB1M	Strong	Biomarker	[332]
ALOX12	TT12ABZ	Strong	Genetic Variation	[333]
ALOX5	TTSJ6Q4	Strong	Biomarker	[334]
ANG	TTURHFP	Strong	Biomarker	[335]
ANGPT2	TTKLQTJ	Strong	Biomarker	[336]
ANGPTL4	TTWALY5	Strong	Altered Expression	[337]
ANXA10	TT0NL6U	Strong	Biomarker	[338]
ANXA2	TT4YANI	Strong	Biomarker	[339]
ANXA5	TT2Z83I	Strong	Biomarker	[340]
AOC3	TT7HC21	Strong	Biomarker	[341]
APC2	TTSMK36	Strong	Biomarker	[342]
APLN	TT87D3J	Strong	Biomarker	[343]
APLNR	TTJ8E43	Strong	Altered Expression	[343]
APOA1	TT5S8DR	Strong	Altered Expression	[344]
APOA4	TTNC3WS	Strong	Biomarker	[345]
APOB	TTN1IE2	Strong	Altered Expression	[346]
APOL1	TTDB8PW	Strong	Biomarker	[347]
AQP1	TTSF1KH	Strong	Posttranslational Modification	[348]
AQP9	TTQEI32	Strong	Biomarker	[349]
ARG1	TT7ZQEV	Strong	Altered Expression	[350]
ARRB1	TTMVD4A	Strong	Biomarker	[351]
ARSA	TTYQANR	Strong	Biomarker	[352]
ARSB	TTESQTG	Strong	Biomarker	[353]
ASAP3	TTB4ZEN	Strong	Altered Expression	[354]
ASIC2	TTVMWLP	Strong	Altered Expression	[355]
ASPA	TT6TLZP	Strong	Genetic Variation	[356]
ASRGL1	TT4WT91	Strong	Biomarker	[357]
ATAD2	TT9A0HI	Strong	Biomarker	[358]
ATF3	TTCE793	Strong	Altered Expression	[359]
ATF4	TTQCKWT	Strong	Biomarker	[360]
ATG7	TTLVB9Z	Strong	Biomarker	[361]
ATP6V1A	TTL2PXZ	Strong	Biomarker	[362]
ATP7B	TTOPO51	Strong	Biomarker	[363]
ATXN2	TTPQJ7P	Strong	Genetic Variation	[364]
AURKB	TT9RTBL	Strong	Biomarker	[365]
AVPR2	TTK8R02	Strong	Altered Expression	[366]
AZGP1	TTUPYLV	Strong	Biomarker	[367]
B2M	TTY7FKA	Strong	Genetic Variation	[368]
BACH1	TT2ME4S	Strong	Biomarker	[369]
BBC3	TT7JUKC	Strong	Biomarker	[370]
BCAT1	TTES57P	Strong	Biomarker	[371]
BCL2L2	TTQ79W8	Strong	Biomarker	[372]
BDKRB1	TTG5QIA	Strong	Altered Expression	[373]
BECN1	TT5M7LN	Strong	Biomarker	[374]
BIRC5	TTTPU1G	Strong	Altered Expression	[375]
BMI1	TTIPNSR	Strong	Altered Expression	[120]
BMP1	TT0L58T	Strong	Genetic Variation	[376]
BMP6	TT07RIB	Strong	Posttranslational Modification	[377]
BMPR2	TTGKF90	Strong	Genetic Variation	[378]
BRD4	TTSRAOU	Strong	Biomarker	[379]
BRIP1	TTZV7LJ	Strong	Genetic Variation	[380]
BRSK1	TTV6WMQ	Strong	Biomarker	[381]
BSG	TT5UJWD	Strong	Biomarker	[382]
BST2	TT90BJT	Strong	Altered Expression	[383]
BTLA	TTER58P	Strong	Genetic Variation	[384]
CA2	TTANPDJ	Strong	Biomarker	[385]
CA4	TTZHA0O	Strong	Posttranslational Modification	[386]
CA6	TTCFSPE	Strong	Genetic Variation	[387]
CA7	TTJC376	Strong	Altered Expression	[388]
CA9	TT2LVK8	Strong	Biomarker	[389]
CACNA1G	TT729IR	Strong	Posttranslational Modification	[390]
CACNA2D2	TTU8P3M	Strong	Posttranslational Modification	[391]
CAD	TT2YT1K	Strong	Biomarker	[392]
CALCR	TTLWS2O	Strong	Biomarker	[393]
CAPN1	TT1WBIJ	Strong	Altered Expression	[394]
CARM1	TTIZQFJ	Strong	Biomarker	[395]
CASP2	TT12VNG	Strong	Biomarker	[396]
CASP4	TT6KIOT	Strong	Genetic Variation	[397]
CASP6	TTKW4ML	Strong	Biomarker	[398]
CBS	TTVZJ7G	Strong	Posttranslational Modification	[399]
CBX7	TTBN3HC	Strong	Altered Expression	[400]
CCK	TT90CMU	Strong	Biomarker	[401]
CCKBR	TTVFO0U	Strong	Altered Expression	[402]
CCL20	TT2XAZY	Strong	Altered Expression	[403]
CCL21	TTLZK1U	Strong	Biomarker	[404]
CCN1	TTPK79J	Strong	Altered Expression	[405]
CCN2	TTIL516	Strong	Altered Expression	[406]
CCNA2	TTAMQ62	Strong	Biomarker	[407]
CCNB1	TT9P6OW	Strong	Altered Expression	[408]
CCNE1	TTCEJ4F	Strong	Biomarker	[409]
CCR1	TTC24WT	Strong	Biomarker	[410]
CCR2	TTFZYTO	Strong	Altered Expression	[411]
CCR6	TTFDB30	Strong	Biomarker	[412]
CCR9	TTIPS8B	Strong	Biomarker	[413]
CD160	TTOFEAS	Strong	Biomarker	[414]
CD163	TTTZ9DE	Strong	Altered Expression	[415]
CD2	TTJDUNO	Strong	Posttranslational Modification	[416]
CD200	TT0BE68	Strong	Biomarker	[417]
CD209	TTBXIM9	Strong	Genetic Variation	[418]
CD24	TTCTYNP	Strong	Altered Expression	[419]
CD248	TTYJWT7	Strong	Altered Expression	[420]
CD320	TT0KV32	Strong	Genetic Variation	[421]
CD36	TTPJMCU	Strong	Biomarker	[422]
CD46	TTMS7DF	Strong	Biomarker	[423]
CD55	TT5Z9WY	Strong	Altered Expression	[424]
CD58	TT5KSBY	Strong	Biomarker	[425]
CD86	TT53XHB	Strong	Genetic Variation	[426]
CD9	TTZEIBV	Strong	Altered Expression	[112]
CD96	TT83C4X	Strong	Biomarker	[427]
CDC25A	TTLZS4Q	Strong	Altered Expression	[428]
CDC25B	TTR0SWN	Strong	Altered Expression	[429]
CDC7	TTSMTDI	Strong	Biomarker	[430]
CDH5	TTXLCFO	Strong	Biomarker	[431]
CDK1	TTH6V3D	Strong	Altered Expression	[432]
CDK2	TT7HF4W	Strong	Altered Expression	[433]
CDK4	TT0PG8F	Strong	Altered Expression	[282]
CDK5	TTL4Q97	Strong	Biomarker	[434]
CDK8	TTBJR4L	Strong	Altered Expression	[435]
CDK9	TT1LVF2	Strong	Biomarker	[436]
CDKN1A	TT9GUW0	Strong	Biomarker	[437]
CEACAM1	TTA9CK4	Strong	Biomarker	[438]
CENPE	TTZD5QR	Strong	Genetic Variation	[439]
CES1	TTMF541	Strong	Altered Expression	[440]
CETP	TTFQAYR	Strong	Biomarker	[441]
CFD	TT8D13I	Strong	Biomarker	[442]
CFTR	TTRLZHP	Strong	Biomarker	[443]
CGA	TTFC29G	Strong	Genetic Variation	[444]
CHEK1	TTTU902	Strong	Genetic Variation	[17]
CHIT1	TTDYX6T	Strong	Genetic Variation	[445]
CHKA	TT10AWB	Strong	Biomarker	[446]
CHRM3	TTQ13Z5	Strong	Biomarker	[447]
CHRNA7	TTLA931	Strong	Altered Expression	[448]
CLCA1	TT3AF4R	Strong	Biomarker	[449]
CLIC1	TT8KZG6	Strong	Altered Expression	[443]
CLN3	TTORF9W	Strong	Biomarker	[450]
COL18A1	TT63DI9	Strong	Biomarker	[451]
COL7A1	TTBCOKN	Strong	Biomarker	[431]
COPS5	TTSTNJR	Strong	Altered Expression	[452]
CPE	TTXPWO6	Strong	Altered Expression	[453]
CPM	TTVOH2M	Strong	Biomarker	[454]
CRAT	TTC8M31	Strong	Altered Expression	[455]
CREB1	TTH4AN3	Strong	Biomarker	[456]
CRY2	TTAO58M	Strong	Biomarker	[40]
CSE1L	TTTRULD	Strong	Altered Expression	[457]
CSF1	TT0IQER	Strong	Biomarker	[458]
CSF2	TTNYZG2	Strong	Biomarker	[223]
CSK	TTX6F0Q	Strong	Biomarker	[459]
CSNK1D	TTH30UI	Strong	Biomarker	[460]
CTCFL	TTY0RZT	Strong	Biomarker	[461]
CTSA	TT5NILS	Strong	Biomarker	[462]
CTSB	TTF2LRI	Strong	Altered Expression	[463]
CTSD	TTPT2QI	Strong	Biomarker	[464]
CTSL	TT36ETB	Strong	Biomarker	[465]
CUBN	TT9YLCR	Strong	Genetic Variation	[466]
CUL3	TTPCU0Q	Strong	Altered Expression	[467]
CXCL1	TTLK1RW	Strong	Altered Expression	[468]
CXCL11	TTWG0RE	Strong	Altered Expression	[469]
CXCL8	TTCTE1G	Strong	Altered Expression	[468]
CXCR2	TT30C9G	Strong	Biomarker	[468]
CXCR3	TT1UCIJ	Strong	Biomarker	[140]
CXCR5	TTIW59R	Strong	Altered Expression	[470]
CYP17A1	TTRA5BZ	Strong	Genetic Variation	[471]
CYP24A1	TT82UI1	Strong	Genetic Variation	[472]
CYP2A6	TTAQ6ZW	Strong	Biomarker	[473]
CYP2B6	TTMH124	Strong	Posttranslational Modification	[474]
CYP3A4	TTWP7HQ	Strong	Genetic Variation	[475]
CYP46A1	TT4EB85	Strong	Altered Expression	[476]
CYP51A1	TT67TDP	Strong	Altered Expression	[476]
CYTH2	TTOM97J	Strong	Biomarker	[477]
DCLK1	TTOHTCY	Strong	Biomarker	[478]
DDX5	TTZKPVC	Strong	Biomarker	[479]
DDX58	TTVB0O3	Strong	Biomarker	[248]
DEK	TT1NMGV	Strong	Biomarker	[480]
DHFR	TTYZVDJ	Strong	Biomarker	[481]
DHODH	TTLVP78	Strong	Biomarker	[482]
DIABLO	TTN74LE	Strong	Biomarker	[483]
DICER1	TTTEOPU	Strong	Genetic Variation	[484]
DLL1	TT9CFQD	Strong	Altered Expression	[485]
DLL4	TTV23LH	Strong	Biomarker	[486]
DNASE1	TTYWGOJ	Strong	Biomarker	[487]
DNM2	TTVRA5G	Strong	Biomarker	[488]
DNMT3A	TTJUALD	Strong	Biomarker	[325]
DNPEP	TTGMFY7	Strong	Altered Expression	[489]
DOT1L	TTSZ8T1	Strong	Biomarker	[490]
DPEP1	TTYUENF	Strong	Biomarker	[491]
DPP4	TTDIGC1	Strong	Biomarker	[492]
DPYSL2	TTZCW3T	Strong	Altered Expression	[493]
DUSP1	TTG8HIM	Strong	Altered Expression	[494]
DUSP5	TTZN92A	Strong	Biomarker	[495]
DUSP8	TTK0TF2	Strong	Biomarker	[496]
DUSP9	TT1GV6C	Strong	Biomarker	[497]
DYRK1A	TTSBVFO	Strong	Altered Expression	[498]
DYRK2	TT84OS6	Strong	Biomarker	[499]
E2F3	TTWIJYH	Strong	Altered Expression	[500]
ECE1	TTQ9RYT	Strong	Altered Expression	[501]
EDNRB	TT3ZTGU	Strong	Biomarker	[502]
EED	TTFNJ4R	Strong	Genetic Variation	[503]
EEF2K	TT1QFLA	Strong	Altered Expression	[504]
EGFL7	TT7WD0H	Strong	Biomarker	[505]
EGLN1	TT9ISBX	Strong	Biomarker	[506]
EGLN2	TTMHFRY	Strong	Genetic Variation	[507]
EGR1	TTE8LGD	Strong	Biomarker	[508]
EIF4E	TTZGCP6	Strong	Biomarker	[405]
EIF4EBP1	TTKGEBL	Strong	Posttranslational Modification	[509]
EIF5A	TTIVCNR	Strong	Altered Expression	[510]
EIF5A2	TTH53G9	Strong	Altered Expression	[511]
EML4	TT92GY4	Strong	Genetic Variation	[512]
ENG	TTB30LE	Strong	Biomarker	[513]
ENPEP	TT9PBIL	Strong	Biomarker	[514]
EP300	TTGH73N	Strong	Altered Expression	[515]
EPAS1	TTWPA54	Strong	Biomarker	[516]
EPCAM	TTZ8WH4	Strong	Biomarker	[517]
EPHA1	TTLFZVU	Strong	Altered Expression	[518]
EPHA6	TTFAHWI	Strong	Genetic Variation	[519]
EPHA7	TTAHTVG	Strong	Biomarker	[520]
EPHA8	TTHZ2LW	Strong	Biomarker	[521]
EPHB3	TT5LM7U	Strong	Biomarker	[522]
EPHB4	TTI4ZX2	Strong	Altered Expression	[523]
EPHB6	TTZEMUY	Strong	Biomarker	[524]
ERAP1	TT60XFL	Strong	Genetic Variation	[525]
ERBB4	TTWALCO	Strong	Altered Expression	[526]
ERN1	TTKIAT3	Strong	Biomarker	[527]
ESR2	TTOM3J0	Strong	Biomarker	[528]
ESRRB	TTKF0XS	Strong	Biomarker	[529]
EYA2	TTUY9C6	Strong	Altered Expression	[530]
EZR	TTE47YC	Strong	Biomarker	[531]
F11R	TT3C8EG	Strong	Genetic Variation	[250]
F13A1	TTXI2RA	Strong	Biomarker	[532]
F2RL1	TTQR74A	Strong	Altered Expression	[533]
F2RL3	TTD0652	Strong	Biomarker	[274]
F3	TT38MDJ	Strong	Biomarker	[534]
F5	TT1O264	Strong	Genetic Variation	[535]
F7	TTF0EGX	Strong	Biomarker	[536]
F9	TTFEZ5Q	Strong	Biomarker	[537]
FABP1	TTIV96N	Strong	Altered Expression	[538]
FABP2	TTS4YLO	Strong	Genetic Variation	[539]
FABP5	TTNT2S6	Strong	Altered Expression	[540]
FADS2	TTT2VDU	Strong	Genetic Variation	[364]
FAP	TTGPQ0F	Strong	Biomarker	[541]
FASN	TT7AOUD	Strong	Biomarker	[542]
FCGR3A	TTIFOC0	Strong	Biomarker	[66]
FDXR	TT3W4IX	Strong	Biomarker	[543]
FES	TTLBY21	Strong	Altered Expression	[521]
FFAR1	TTB8FUC	Strong	Altered Expression	[544]
FFAR4	TT08JVB	Strong	Altered Expression	[545]
FGF10	TTNPEFX	Strong	Altered Expression	[546]
FGF18	TT6ICRA	Strong	Genetic Variation	[91]
FGF19	TTGCH11	Strong	Biomarker	[547]
FGF2	TTGKIED	Strong	Altered Expression	[548]
FGF4	TTCEKVZ	Strong	Biomarker	[549]
FGF7	TTFY134	Strong	Biomarker	[550]
FGF8	TTIUF3J	Strong	Biomarker	[551]
FGFR3	TTST7KB	Strong	Altered Expression	[552]
FGFR4	TT1KX2S	Strong	Biomarker	[553]
FGL2	TTYBS89	Strong	Altered Expression	[554]
FGR	TTPOGS1	Strong	Biomarker	[555]
FHIT	TTMS54D	Strong	Genetic Variation	[556]
FKBP5	TT0J5KQ	Strong	Genetic Variation	[215]
FN1	TTPJ921	Strong	Altered Expression	[557]
FOLR1	TTVC37M	Strong	Altered Expression	[558]
FOS	TTOM5AU	Strong	Biomarker	[559]
FOSL1	TTY8LZG	Strong	Biomarker	[560]
FOXC1	TTNT3YA	Strong	Biomarker	[203]
FOXC2	TTLBAP1	Strong	Altered Expression	[561]
FOXJ2	TTV1FDA	Strong	Biomarker	[562]
FOXM1	TTD3KOX	Strong	Altered Expression	[563]
FOXO1	TTLRVIA	Strong	Altered Expression	[564]
FOXP3	TT1X3QF	Strong	Biomarker	[565]
FOXQ1	TTEJZOL	Strong	Biomarker	[566]
FPR1	TT5Y4EM	Strong	Genetic Variation	[567]
FPR2	TTOJ1NF	Strong	Altered Expression	[568]
FTH1	TT975ZT	Strong	Biomarker	[120]
FUT3	TTUPAD7	Strong	Biomarker	[569]
FUT4	TTNV1KZ	Strong	Altered Expression	[570]
FZD10	TTP1S2F	Strong	Biomarker	[571]
FZD7	TTUQMO5	Strong	Biomarker	[572]
GAS6	TT69QD2	Strong	Biomarker	[573]
GATA3	TT45KOB	Strong	Biomarker	[574]
GATA4	TT1VDN2	Strong	Biomarker	[575]
GCLM	TTNFESW	Strong	Biomarker	[576]
GGT1	TTZVT7O	Strong	Genetic Variation	[577]
GH1	TTT3YKH	Strong	Biomarker	[578]
GHRHR	TTG4R8V	Strong	Posttranslational Modification	[579]
GJC1	TTEP7OC	Strong	Posttranslational Modification	[580]
GOT1	TTU507L	Strong	Biomarker	[581]
GPA33	TT96HUR	Strong	Biomarker	[582]
GPC3	TTJTSX4	Strong	Altered Expression	[583]
GPER1	TTDSB34	Strong	Biomarker	[584]
GPNMB	TT7315J	Strong	Biomarker	[585]
GPR31	TT71ZLK	Strong	Altered Expression	[586]
GPR55	TTNET8J	Strong	Altered Expression	[103]
GPRC5D	TTHRAPJ	Strong	Genetic Variation	[587]
GPRC6A	TTI1PRE	Strong	Genetic Variation	[588]
GRB2	TTEYRJ9	Strong	Altered Expression	[589]
GRHL2	TTUGH4C	Strong	Biomarker	[590]
GRIN2A	TTKJEMQ	Strong	Altered Expression	[76]
GRN	TT0LWE3	Strong	Biomarker	[591]
GSK3B	TTRSMW9	Strong	Altered Expression	[374]
GSR	TTEP6RV	Strong	Altered Expression	[592]
GSTA1	TT4P8DE	Strong	Genetic Variation	[593]
GUCY2C	TTLDPRG	Strong	Biomarker	[594]
GZMB	TTKEPHX	Strong	Biomarker	[595]
HAX1	TT21BYA	Strong	Altered Expression	[596]
HDAC1	TT6R7JZ	Strong	Altered Expression	[597]
HDAC2	TTSHTOI	Strong	Biomarker	[598]
HDAC6	TT5ZKDI	Strong	Biomarker	[560]
HDAC7	TTMUEK1	Strong	Biomarker	[599]
HDAC9	TT8M4E1	Strong	Altered Expression	[600]
HDC	TTV9GOF	Strong	Biomarker	[601]
HDGF	TTKGV26	Strong	Altered Expression	[602]
HGF	TT4V2JM	Strong	Biomarker	[603]
HIPK2	TTOB49C	Strong	Genetic Variation	[604]
HKDC1	TTVUI8G	Strong	Biomarker	[605]
HLA-A	TTHONFT	Strong	Biomarker	[606]
HLA-B	TTGS10J	Strong	Genetic Variation	[607]
HLA-G	TTLKFB3	Strong	Biomarker	[608]
HMGA1	TTBA219	Strong	Altered Expression	[609]
HMGA2	TTSTVM0	Strong	Altered Expression	[610]
HMGB2	TTA78JQ	Strong	Biomarker	[611]
HMGCR	TTPADOQ	Strong	Biomarker	[612]
HMGCS2	TTS0EZJ	Strong	Altered Expression	[613]
HNF4A	TT2F3CD	Strong	Biomarker	[464]
HNMT	TT2B6EV	Strong	Genetic Variation	[614]
HNRNPA1	TTPJ9XK	Strong	Biomarker	[615]
HOXA5	TTXSVQP	Strong	Altered Expression	[616]
HPSE	TTR7GJO	Strong	Biomarker	[617]
HRH1	TTTIBOJ	Strong	Biomarker	[618]
HRH2	TTQHJ1K	Strong	Altered Expression	[618]
HRH4	TTXJ178	Strong	Altered Expression	[619]
HSD11B1	TTN7BL9	Strong	Altered Expression	[620]
HSD11B2	TT9H85R	Strong	Biomarker	[621]
HSD17B13	TTDJYZR	Strong	Altered Expression	[622]
HSF1	TTN6STZ	Strong	Altered Expression	[623]
HSP90AB1	TTH5YN2	Strong	Altered Expression	[624]
HTATIP2	TTC6IX5	Strong	Altered Expression	[625]
HTR1D	TT6MSOK	Strong	Altered Expression	[626]
ICOSLG	TTB9Z8R	Strong	Altered Expression	[627]
IDO1	TTZJYKH	Strong	Biomarker	[628]
IDUA	TT0IUKX	Strong	Genetic Variation	[629]
IFNA2	TTSIUJ9	Strong	Biomarker	[630]
IFNAR1	TTSYFMA	Strong	Altered Expression	[631]
IFNGR2	TT13TL0	Strong	Genetic Variation	[268]
IGF2	TTE8WGO	Strong	Biomarker	[632]
IGF2R	TTPNE41	Strong	Biomarker	[633]
IGFBP1	TTCJTWF	Strong	Biomarker	[634]
IGFBP2	TTU4QSN	Strong	Altered Expression	[635]
IGFBP6	TTLAYV8	Strong	Biomarker	[636]
IGFBP7	TTUQ01B	Strong	Biomarker	[637]
IKZF3	TTCZVFZ	Strong	Biomarker	[638]
IL12A	TTRTK6Y	Strong	Genetic Variation	[639]
IL13	TT0GVCH	Strong	Altered Expression	[640]
IL13RA2	TTMPZ7V	Strong	Biomarker	[641]
IL15	TTJFA35	Strong	Biomarker	[642]
IL16	TTW4R0B	Strong	Genetic Variation	[643]
IL2	TTF89GD	Strong	Biomarker	[644]
IL21	TT9QEJ6	Strong	Altered Expression	[645]
IL22	TTLDX4N	Strong	Biomarker	[247]
IL23A	TTC1GLB	Strong	Biomarker	[646]
IL31RA	TT9HPX0	Strong	Biomarker	[647]
IL33	TT5MD4P	Strong	Biomarker	[648]
IL37	TTQTX98	Strong	Altered Expression	[649]
IL7	TT8FRMO	Strong	Biomarker	[650]
IL7R	TTAWI51	Strong	Genetic Variation	[651]
ILK	TT7ALZG	Strong	Altered Expression	[652]
IMP3	TTEJA2R	Strong	Altered Expression	[653]
IMPDH2	TTTB4UP	Strong	Altered Expression	[654]
INHBA	TTVB30D	Strong	Biomarker	[655]
INSR	TTCBFJO	Strong	Genetic Variation	[656]
IRAK3	TTBPJOK	Strong	Altered Expression	[657]
IRAK4	TTILUKB	Strong	Biomarker	[658]
IRS1	TTAJSQ0	Strong	Posttranslational Modification	[659]
IRS2	TTF95B8	Strong	Genetic Variation	[660]
ITGA1	TTPERWV	Strong	Genetic Variation	[661]
ITGA4	TTJMF9P	Strong	Biomarker	[662]
ITGA5	TTHIZP9	Strong	Altered Expression	[663]
ITGA6	TT165T3	Strong	Altered Expression	[354]
ITGB6	TTKQSXZ	Strong	Biomarker	[664]
ITGB8	TTIF29E	Strong	Biomarker	[665]
ITPR3	TTH1769	Strong	Biomarker	[666]
JAK1	TT6DM01	Strong	Biomarker	[667]
JAK2	TTRMX3V	Strong	Altered Expression	[668]
JMJD1C	TTBISK4	Strong	Biomarker	[669]
JUN	TTS7IR5	Strong	Altered Expression	[670]
KAT2B	TTVK7SB	Strong	Altered Expression	[671]
KCNA3	TTY3UE6	Strong	Altered Expression	[672]
KCNA5	TTW0CMT	Strong	Biomarker	[673]
KCNH1	TT9XKUC	Strong	Genetic Variation	[607]
KCNN4	TT7M9I6	Strong	Biomarker	[674]
KCNQ1	TT846HF	Strong	Biomarker	[675]
KDM1A	TTNR0UQ	Strong	Biomarker	[676]
KDM3A	TTKXS4A	Strong	Altered Expression	[677]
KDM5B	TTCLI75	Strong	Biomarker	[678]
KDM6B	TTDIJUQ	Strong	Biomarker	[679]
KEAP1	TT3Z6Y9	Strong	Altered Expression	[369]
KHDRBS1	TTAT6C7	Strong	Biomarker	[680]
KIF11	TTBGTCW	Strong	Biomarker	[681]
KIF26B	TTQWICZ	Strong	Biomarker	[682]
KIR2DL2	TTU0P73	Strong	Genetic Variation	[683]
KIR2DS2	TTV3CFI	Strong	Genetic Variation	[683]
KIR3DL2	TTQH3N0	Strong	Genetic Variation	[684]
KISS1	TTU2O6T	Strong	Altered Expression	[96]
KLF4	TTTI53X	Strong	Biomarker	[685]
KLK6	TTLPF4X	Strong	Altered Expression	[686]
KLK7	TTE6GTB	Strong	Altered Expression	[687]
KLK8	TTH5MRS	Strong	Altered Expression	[688]
KLRK1	TTLRN4A	Strong	Biomarker	[689]
KMT5A	TTGC95K	Strong	Biomarker	[690]
KNG1	TTDJ4MY	Strong	Biomarker	[691]
KPNB1	TTHOJ5F	Strong	Biomarker	[692]
KRT17	TTKV0EC	Strong	Altered Expression	[693]
L1CAM	TTC9D3K	Strong	Altered Expression	[694]
LAG3	TTNVXAW	Strong	Posttranslational Modification	[300]
LAMP1	TTC214J	Strong	Biomarker	[695]
LARP1	TTSN1YP	Strong	Biomarker	[696]
LASP1	TTZJA87	Strong	Biomarker	[697]
LATS2	TTML7FG	Strong	Altered Expression	[698]
LCN2	TTKTLAI	Strong	Biomarker	[699]
LCT	TTA0OSE	Strong	Genetic Variation	[700]
LDHA	TTW76JE	Strong	Biomarker	[701]
LDLR	TTH0DUS	Strong	Biomarker	[120]
LEP	TTBJEZ5	Strong	Genetic Variation	[702]
LEPR	TT0HD6V	Strong	Biomarker	[703]
LGALS3	TTFPQV7	Strong	Altered Expression	[704]
LGMN	TTPTWV5	Strong	Altered Expression	[705]
LGR4	TTY6C71	Strong	Biomarker	[706]
LGR5	TTTSGRH	Strong	Biomarker	[707]
LIFR	TTID542	Strong	Biomarker	[708]
LILRB1	TTC0QRJ	Strong	Biomarker	[709]
LILRB2	TTHC6XU	Strong	Biomarker	[710]
LILRB4	TTREOKA	Strong	Altered Expression	[711]
LIN28A	TTO50LN	Strong	Biomarker	[712]
LIPE	TTLUQ8E	Strong	Biomarker	[713]
LMO2	TTFX379	Strong	Altered Expression	[714]
LONP1	TTM1VPZ	Strong	Biomarker	[715]
LOX	TTQHNAM	Strong	Biomarker	[716]
LOXL2	TTFSUHX	Strong	Biomarker	[717]
LPAR3	TTE2YJR	Strong	Genetic Variation	[588]
LRP2	TTPH1AJ	Strong	Genetic Variation	[466]
LRP6	TTSXOWE	Strong	Altered Expression	[718]
LTA4H	TTXZEAJ	Strong	Altered Expression	[719]
LTB4R	TTN53ZF	Strong	Altered Expression	[719]
LTB4R2	TTVJX54	Strong	Biomarker	[720]
LY96	TT8S9AV	Strong	Biomarker	[721]
LYVE1	TTG8DNU	Strong	Biomarker	[722]
MAD1L1	TTNE9U7	Strong	Genetic Variation	[723]
MAGEA3	TTWSKHD	Strong	Biomarker	[724]
MALT1	TTCI81G	Strong	Biomarker	[725]
MAP2K2	TT8H9GB	Strong	Biomarker	[726]
MAP2K5	TTV3O87	Strong	Altered Expression	[727]
MAP2K7	TT6QY3J	Strong	Altered Expression	[728]
MAP3K7	TTJQT60	Strong	Biomarker	[729]
MAP4K1	TTSHWUP	Strong	Genetic Variation	[730]
MAPK3	TT1MG9E	Strong	Biomarker	[731]
MAPK7	TTU6FSC	Strong	Biomarker	[732]
MAPK8	TT0K6EO	Strong	Biomarker	[733]
MAPK9	TT3IVG2	Strong	Altered Expression	[734]
MAPKAP1	TTWDKCL	Strong	Altered Expression	[735]
MAPKAPK3	TTFS4VU	Strong	Biomarker	[715]
MARCKS	TTHRM39	Strong	Biomarker	[736]
MAS1	TTOISYB	Strong	Genetic Variation	[737]
MBL2	TTMQDZ5	Strong	Genetic Variation	[738]
MCL1	TTL53M6	Strong	Biomarker	[509]
MCM7	TT1RM3F	Strong	Biomarker	[739]
MELK	TTBZOTY	Strong	Biomarker	[740]
MELTF	TT8OBT3	Strong	Altered Expression	[741]
MERTK	TTO7LKR	Strong	Biomarker	[742]
MFGE8	TT1GLAJ	Strong	Altered Expression	[743]
MGLL	TTZ963I	Strong	Altered Expression	[744]
MIA	TT5HNVS	Strong	Biomarker	[745]
MKNK1	TTEZAUX	Strong	Biomarker	[746]
MMP11	TTZW4MV	Strong	Altered Expression	[747]
MMP12	TTXZ0KQ	Strong	Genetic Variation	[748]
MMP13	TTHY57M	Strong	Biomarker	[747]
MMP14	TTJ4QE7	Strong	Altered Expression	[749]
MPL	TTIHYA4	Strong	Biomarker	[750]
MPO	TTVCZPI	Strong	Altered Expression	[751]
MRGPRX1	TTIX6PK	Strong	Genetic Variation	[588]
MSLN	TT4RXME	Strong	Altered Expression	[752]
MSMB	TTYH1ZK	Strong	Biomarker	[321]
MST1R	TTBQ3OC	Strong	Altered Expression	[753]
MSTN	TTM8I2X	Strong	Biomarker	[754]
MTDH	TTH6SA5	Strong	Biomarker	[755]
MUC15	TTGQ6MI	Strong	Altered Expression	[756]
MUC16	TTC1PS3	Strong	Biomarker	[275]
MYB	TT8V13P	Strong	Altered Expression	[757]
MYC	TTNQ5ZP	Strong	Biomarker	[758]
MYCBP	TTVW4XU	Strong	Altered Expression	[759]
MYCN	TT9JBY5	Strong	Genetic Variation	[760]
MYD88	TTB6Q2O	Strong	Biomarker	[761]
NAAA	TTMN4HY	Strong	Biomarker	[762]
NACC1	TT4AQ5F	Strong	Altered Expression	[763]
NAMPT	TTD1WIG	Strong	Altered Expression	[764]
NAPRT	TTVR1FW	Strong	Altered Expression	[765]
NCK1	TTMA3VF	Strong	Altered Expression	[766]
NCOA3	TT124R0	Strong	Biomarker	[767]
NCR1	TTQNRJM	Strong	Altered Expression	[768]
NDUFA13	TTRU1NG	Strong	Altered Expression	[769]
NECTIN4	TTPO9EG	Strong	Altered Expression	[770]
NEDD4	TT1QU6G	Strong	Biomarker	[771]
NEDD8	TTNDC4K	Strong	Biomarker	[772]
NEDD9	TT1UREA	Strong	Biomarker	[773]
NEK2	TT3VZ24	Strong	Biomarker	[774]
NF2	TTZIK7P	Strong	Biomarker	[775]
NFKB1	TTUIZKC	Strong	Biomarker	[776]
NLRP1	TTQX29T	Strong	Biomarker	[777]
NOD1	TTYSRXM	Strong	Altered Expression	[778]
NOS1	TTZUFI5	Strong	Genetic Variation	[364]
NOTCH2	TT82FVD	Strong	Biomarker	[779]
NOTCH4	TTXDIK2	Strong	Genetic Variation	[294]
NPM1	TTHBS98	Strong	Altered Expression	[780]
NPTX2	TTNJ5A6	Strong	Biomarker	[781]
NR0B2	TT25A9Q	Strong	Altered Expression	[782]
NR1H2	TTXA6PH	Strong	Genetic Variation	[783]
NR1H3	TTECBXN	Strong	Altered Expression	[784]
NR1I3	TTRANFM	Strong	Biomarker	[785]
NR3C2	TT26PHO	Strong	Altered Expression	[786]
NTSR1	TTTUMEP	Strong	Altered Expression	[787]
NTSR2	TT31Q0V	Strong	Altered Expression	[787]
NUF2	TTIXBFP	Strong	Biomarker	[788]
ODC1	TTUMGNO	Strong	Altered Expression	[789]
OGDH	TTH8T6I	Strong	Genetic Variation	[790]
OLFM4	TTK1CX7	Strong	Biomarker	[791]
OLR1	TTKSND3	Strong	Biomarker	[792]
OSMR	TTAH0KM	Strong	Posttranslational Modification	[793]
OTC	TT5KIO9	Strong	Altered Expression	[794]
OXER1	TT7WBSV	Strong	Genetic Variation	[588]
P2RX7	TT473XN	Strong	Altered Expression	[795]
P2RY6	TTNVSKA	Strong	Biomarker	[796]
PABPC1	TTHC8EF	Strong	Biomarker	[797]
PADI4	TTQHAXM	Strong	Biomarker	[798]
PAK1	TTFN95D	Strong	Biomarker	[799]
PAM	TTF4ZPC	Strong	Biomarker	[450]
PARP1	TTVDSZ0	Strong	Altered Expression	[800]
PBRM1	TTH8ZRL	Strong	Biomarker	[801]
PCCA	TT1JDE3	Strong	Genetic Variation	[790]
PCCB	TT5LURU	Strong	Altered Expression	[802]
PCSK2	TT46F0P	Strong	Altered Expression	[693]
PDCD1LG2	TTW14O3	Strong	Altered Expression	[803]
PDE10A	TTJW4LU	Strong	Biomarker	[804]
PDE2A	TTJGW1Z	Strong	Altered Expression	[805]
PDE7A	TT1BC3A	Strong	Biomarker	[280]
PDGFA	TTSM78N	Strong	Biomarker	[806]
PDGFC	TTOABM9	Strong	Altered Expression	[393]
PDGFD	TTSN0GA	Strong	Biomarker	[807]
PDGFRB	TTI7421	Strong	Biomarker	[806]
PDK1	TTCZOF2	Strong	Biomarker	[808]
PDPK1	TTYMGWX	Strong	Altered Expression	[809]
PDXP	TT9UYG4	Strong	Genetic Variation	[810]
PECAM1	TT4EZB2	Strong	Altered Expression	[811]
PFKFB3	TTTHMQJ	Strong	Biomarker	[812]
PGF	TT48I1Y	Strong	Altered Expression	[813]
PGR	TTUV8G9	Strong	Biomarker	[814]
PHB	TT6U071	Strong	Altered Expression	[815]
PHF8	TT81PFE	Strong	Biomarker	[816]
PHGDH	TT8DRCK	Strong	Biomarker	[817]
PIGU	TT2LHI6	Strong	Genetic Variation	[215]
PIM3	TTCGOIN	Strong	Altered Expression	[818]
PINX1	TT4FJ3A	Strong	Biomarker	[819]
PKD2L1	TTAHD89	Strong	Biomarker	[820]
PKLR	TT31N4S	Strong	Biomarker	[821]
PKM	TT4LOT8	Strong	Biomarker	[822]
PLA2G1B	TT9V5JH	Strong	Genetic Variation	[823]
PLA2G2A	TTO8QRU	Strong	Genetic Variation	[823]
PLA2G4A	TTT1JVS	Strong	Biomarker	[824]
PLA2G4C	TTBYG4O	Strong	Genetic Variation	[825]
PLCG1	TT6T4JI	Strong	Biomarker	[826]
PLD1	TT3T17P	Strong	Biomarker	[827]
PLD2	TTRLMKF	Strong	Biomarker	[828]
PLG	TTP86E2	Strong	Altered Expression	[829]
PLK2	TT976FS	Strong	Biomarker	[830]
PLOD2	TT8MEUD	Strong	Biomarker	[831]
PMS1	TTX1ISF	Strong	Biomarker	[832]
POSTN	TT8ALTZ	Strong	Biomarker	[833]
PPARD	TT2JWF6	Strong	Altered Expression	[516]
PPARGC1B	TTKSQ3W	Strong	Altered Expression	[834]
PPAT	TTZFTY4	Strong	Genetic Variation	[790]
PPIA	TTL2ADK	Strong	Biomarker	[835]
PPIB	TT6ZFQ4	Strong	Biomarker	[836]
PPM1A	TTLA7IX	Strong	Biomarker	[837]
PPM1D	TTENJAB	Strong	Altered Expression	[838]
PPP1CA	TTFLH0E	Strong	Altered Expression	[839]
PPP2CA	TTHTKNY	Strong	Altered Expression	[840]
PPP3CA	TTA4LDE	Strong	Genetic Variation	[841]
PPY	TTIB95A	Strong	Altered Expression	[842]
PRCP	TTTJZ4M	Strong	Genetic Variation	[376]
PRKCA	TTFJ8Q1	Strong	Biomarker	[843]
PRKCB	TTYPXQF	Strong	Biomarker	[843]
PRKCE	TT57MT2	Strong	Biomarker	[844]
PRKD1	TTSLUMT	Strong	Altered Expression	[845]
PRKDC	TTK3PY9	Strong	Biomarker	[846]
PRNP	TTY5F9C	Strong	Biomarker	[847]
PROKR2	TTM67AX	Strong	Biomarker	[848]
PRSS1	TT2WR1T	Strong	Genetic Variation	[849]
PSMB8	TTEAD9J	Strong	Biomarker	[850]
PSMD10	TT2H4LN	Strong	Biomarker	[851]
PTBP1	TTWMX0U	Strong	Biomarker	[852]
PTGER2	TT1ZAVI	Strong	Genetic Variation	[853]
PTGER4	TT79WV3	Strong	Biomarker	[643]
PTK2	TTON5IT	Strong	Altered Expression	[854]
PTK7	TTXH2ZN	Strong	Altered Expression	[855]
PTP4A3	TT7YM8D	Strong	Biomarker	[856]
PTPN1	TTELIN2	Strong	Biomarker	[857]
PTPN14	TTNIR6C	Strong	Posttranslational Modification	[858]
PTPN6	TT369M5	Strong	Altered Expression	[782]
PTPRB	TT64I9Q	Strong	Biomarker	[859]
PTPRS	TTCWXFA	Strong	Biomarker	[860]
PTPRZ1	TT4SEA8	Strong	Biomarker	[861]
PYY	TTVFJLX	Strong	Biomarker	[862]
RAB22A	TTAJ746	Strong	Biomarker	[863]
RAC1	TT2M9CG	Strong	Altered Expression	[864]
RALBP1	TTVSRUA	Strong	Biomarker	[865]
RARB	TTISP28	Strong	Biomarker	[866]
RARG	TT1Q3IE	Strong	Biomarker	[867]
RBCK1	TTIKUVC	Strong	Altered Expression	[868]
RBPJ	TT72D4Z	Strong	Biomarker	[869]
RCE1	TT2AP5B	Strong	Altered Expression	[870]
REG3A	TTL4H8N	Strong	Biomarker	[871]
RENBP	TTZCG0Q	Strong	Genetic Variation	[872]
RET	TT4DXQT	Strong	Biomarker	[237]
RHO	TTH0KSX	Strong	Biomarker	[873]
RNF43	TTD91BL	Strong	Genetic Variation	[874]
RNF7	TTODWGT	Strong	Biomarker	[875]
RNMT	TTG45HY	Strong	Biomarker	[876]
RNPEP	TTD74YX	Strong	Biomarker	[877]
ROCK1	TTZN7RP	Strong	Biomarker	[878]
ROR2	TTUDPCI	Strong	Biomarker	[879]
RORB	TTGB2LZ	Strong	Altered Expression	[880]
ROS1	TTSZ6Y3	Strong	Biomarker	[881]
RPE65	TTBOH16	Strong	Altered Expression	[882]
RPGR	TTHBDA9	Strong	Biomarker	[883]
RPS6KA3	TTUM2ZR	Strong	Biomarker	[884]
RPS6KA5	TTYXEPL	Strong	Genetic Variation	[885]
RPS6KA6	TT3KYWB	Strong	Biomarker	[886]
RPS6KB2	TTMVQXO	Strong	Biomarker	[887]
RPSA	TTLUW5B	Strong	Biomarker	[888]
RRM2	TT1S4LJ	Strong	Biomarker	[324]
RSPO1	TTI9HL4	Strong	Biomarker	[889]
RSPO3	TT7HJTF	Strong	Biomarker	[890]
RTN4	TT7GXMU	Strong	Biomarker	[891]
RTN4R	TTVRZUO	Strong	Altered Expression	[892]
RUNX2	TTD6SZ8	Strong	Altered Expression	[893]
RXRA	TT6PEUO	Strong	Altered Expression	[894]
S100A4	TTPR5SX	Strong	Biomarker	[895]
S100A6	TT716MY	Strong	Biomarker	[896]
S100A9	TT0TMQG	Strong	Biomarker	[897]
S1PR1	TT9JZCK	Strong	Altered Expression	[898]
SATB1	TTLFRIC	Strong	Biomarker	[899]
SCD	TT6RIOV	Strong	Altered Expression	[900]
SCN10A	TT90XZ8	Strong	Biomarker	[901]
SCN1A	TTANOZH	Strong	Altered Expression	[763]
SCUBE2	TTWREQP	Strong	Biomarker	[902]
SDC1	TTYDSVG	Strong	Biomarker	[903]
SDC2	TT5H2F0	Strong	Altered Expression	[904]
SELE	TT1PL7M	Strong	Biomarker	[905]
SERPINA1	TTA7UJC	Strong	Altered Expression	[906]
SERPINB3	TT6QLPX	Strong	Biomarker	[907]
SERPINB5	TT1KW50	Strong	Altered Expression	[908]
SERPINE1	TTTO43N	Strong	Altered Expression	[626]
SERPINH1	TTPSWQG	Strong	Biomarker	[909]
SETD2	TTPC3H4	Strong	Biomarker	[910]
SFRP4	TTX8I1Y	Strong	Genetic Variation	[911]
SGK1	TTTV8EJ	Strong	Biomarker	[912]
SGO1	TTBPKGD	Strong	Genetic Variation	[913]
SH2B3	TT36N7Z	Strong	Altered Expression	[914]
SHCBP1	TTZ9WGL	Strong	Biomarker	[450]
SHH	TTIENCJ	Strong	Biomarker	[915]
SIK1	TT1H6LC	Strong	Biomarker	[916]
SIRT1	TTUF2HO	Strong	Biomarker	[917]
SIRT2	TTLKF5M	Strong	Biomarker	[918]
SIRT3	TTVZLIJ	Strong	Altered Expression	[919]
SIRT5	TTH0IOD	Strong	Biomarker	[920]
SKP2	TT5B2EO	Strong	Biomarker	[921]
SLC11A2	TT2IS7P	Strong	Biomarker	[922]
SLC12A3	TTP362L	Strong	Altered Expression	[923]
SLC12A5	TTH6UZY	Strong	Biomarker	[924]
SLC16A3	TTG6VD5	Strong	Altered Expression	[925]
SLC19A2	TT2A1DZ	Strong	Biomarker	[926]
SLC1A1	TTG2A6F	Strong	Altered Expression	[927]
SLC1A2	TT2F078	Strong	Biomarker	[928]
SLC1A3	TT8WRDA	Strong	Altered Expression	[927]
SLC1A5	TTF7WRM	Strong	Biomarker	[929]
SLC22A16	TTITAVR	Strong	Genetic Variation	[930]
SLC22A2	TT0XOJN	Strong	Biomarker	[931]
SLC23A2	TTOP832	Strong	Altered Expression	[932]
SLC25A1	TTTD730	Strong	Biomarker	[933]
SLC27A4	TT20AYF	Strong	Biomarker	[934]
SLC28A2	TTVP9IQ	Strong	Biomarker	[935]
SLC29A1	TTLXAKE	Strong	Biomarker	[936]
SLC38A7	TTEARWC	Strong	Biomarker	[293]
SLC3A2	TT5CZSM	Strong	Biomarker	[293]
SLC46A1	TTY8Z2E	Strong	Biomarker	[280]
SLC5A2	TTF8JAT	Strong	Biomarker	[937]
SLC5A5	TTW7HI9	Strong	Biomarker	[938]
SLC6A12	TTQBMPI	Strong	Biomarker	[939]
SLC6A2	TTAWNKZ	Strong	Genetic Variation	[229]
SLC6A4	TT3ROYC	Strong	Genetic Variation	[940]
SLC7A1	TT4S150	Strong	Altered Expression	[455]
SLC8A1	TTCF82X	Strong	Altered Expression	[941]
SLCO1B1	TTFGXEB	Strong	Genetic Variation	[942]
SLCO1B3	TTU86P0	Strong	Altered Expression	[943]
SLCO3A1	TT5CE6L	Strong	Altered Expression	[944]
SLIT2	TTDWK85	Strong	Altered Expression	[945]
SMAD1	TT9GR53	Strong	Biomarker	[946]
SMAD6	TTON5JB	Strong	Genetic Variation	[215]
SMAD9	TTX8EBV	Strong	Genetic Variation	[215]
SMARCA4	TTVQEZS	Strong	Altered Expression	[947]
SMC2	TTS8D17	Strong	Altered Expression	[948]
SMYD3	TTKLJYX	Strong	Biomarker	[949]
SNCA	TT08OSU	Strong	Biomarker	[950]
SNCG	TT5TQNZ	Strong	Altered Expression	[951]
SOD2	TT9O4C5	Strong	Altered Expression	[952]
SORT1	TTRX9AV	Strong	Biomarker	[953]
SOX5	TTXHSZK	Strong	Biomarker	[954]
SP1	TTZEP6S	Strong	Altered Expression	[955]
SPARC	TTBQFM7	Strong	Biomarker	[956]
SPDEF	TT2ZUPY	Strong	Altered Expression	[957]
SPHK1	TTOHFIY	Strong	Altered Expression	[958]
SPN	TTOZAX0	Strong	Altered Expression	[959]
SPOCK1	TTF23RE	Strong	Altered Expression	[960]
SPRY1	TT0PSN6	Strong	Altered Expression	[961]
SPTBN1	TTS9BDA	Strong	Biomarker	[962]
SQLE	TTE14XG	Strong	Biomarker	[963]
SQSTM1	TTOT2RY	Strong	Biomarker	[680]
SREBF1	TTER0UB	Strong	Biomarker	[964]
SRGN	TTCHB06	Strong	Biomarker	[965]
SRPK1	TTU3WV6	Strong	Biomarker	[966]
SST	TTWF7UG	Strong	Biomarker	[967]
ST8SIA4	TTDP8YM	Strong	Genetic Variation	[968]
STAT6	TTWOE1T	Strong	Altered Expression	[969]
STC1	TTDLUER	Strong	Altered Expression	[970]
STC2	TT4EFTR	Strong	Biomarker	[971]
STEAP1	TT9E64S	Strong	Biomarker	[972]
STEAP2	TTOXF5J	Strong	Altered Expression	[973]
STK17A	TTEYF03	Strong	Biomarker	[974]
STK4	TTCPLVN	Strong	Biomarker	[715]
STOML2	TTOI329	Strong	Biomarker	[975]
STRAP	TT165DP	Strong	Altered Expression	[976]
STS	TTHM0R1	Strong	Altered Expression	[977]
STYK1	TTRMCYJ	Strong	Altered Expression	[978]
SULF2	TTLQTHB	Strong	Biomarker	[979]
SYK	TT2HUPM	Strong	Biomarker	[980]
TACSTD2	TTP2HE5	Strong	Altered Expression	[981]
TAP1	TT7JZI8	Strong	Altered Expression	[982]
TBL1X	TTAL6S1	Strong	Genetic Variation	[983]
TBL1XR1	TTYXT16	Strong	Altered Expression	[984]
TBX21	TTNF9PH	Strong	Altered Expression	[985]
TCF3	TTULOD8	Strong	Altered Expression	[986]
TCL1A	TTUKRDV	Strong	Altered Expression	[987]
TDG	TTEXRQD	Strong	Genetic Variation	[988]
TDGF1	TTN7HMG	Strong	Altered Expression	[220]
TDP2	TTYF26D	Strong	Genetic Variation	[989]
TERF2	TT5XSLT	Strong	Biomarker	[979]
TFAP2A	TTDY4BS	Strong	Biomarker	[990]
TFF1	TTNOJIZ	Strong	Altered Expression	[991]
TGFB3	TTWOMY8	Strong	Biomarker	[992]
TGFBR2	TTZE3P7	Strong	Biomarker	[993]
TGM2	TT2F4OL	Strong	Altered Expression	[994]
THBS1	TTKI0H1	Strong	Biomarker	[204]
TIAM1	TTNU6I5	Strong	Altered Expression	[995]
TIE1	TTT4236	Strong	Altered Expression	[996]
TIRAP	TTKU0LS	Strong	Biomarker	[997]
TKTL1	TTNQ1J3	Strong	Biomarker	[998]
TLR1	TTW14D0	Strong	Genetic Variation	[999]
TLR2	TTY7ZHS	Strong	Altered Expression	[1000]
TLR4	TTISGCA	Strong	Altered Expression	[747]
TLR5	TTCXP8J	Strong	Biomarker	[997]
TLR9	TTSHG0T	Strong	Altered Expression	[1001]
TMSB4X	TTMVAIU	Strong	Biomarker	[1002]
TNFAIP3	TT5W0IO	Strong	Altered Expression	[1003]
TNFRSF10A	TT5WLRX	Strong	Genetic Variation	[1004]
TNFRSF10B	TTW20TU	Strong	Biomarker	[1005]
TNFRSF14	TTWGTC1	Strong	Altered Expression	[1006]
TNFRSF4	TTL31H0	Strong	Altered Expression	[1007]
TNFRSF9	TTPW9LJ	Strong	Altered Expression	[1008]
TNFSF10	TTA5MS9	Strong	Altered Expression	[699]
TNFSF13	TTOI1RM	Strong	Altered Expression	[1009]
TNFSF14	TTKVENM	Strong	Biomarker	[1010]
TNFSF15	TTEST6I	Strong	Biomarker	[1011]
TNFSF4	TTBW580	Strong	Biomarker	[1012]
TNIK	TTPB1W3	Strong	Biomarker	[1013]
TNK2	TTIET93	Strong	Biomarker	[1014]
TNS4	TT1K65C	Strong	Biomarker	[1015]
TOP1	TTGTQHC	Strong	Biomarker	[1016]
TOP2A	TTCGY2K	Strong	Altered Expression	[1017]
TOP2B	TT4NVEM	Strong	Altered Expression	[1018]
TP53BP1	TTX4UE9	Strong	Altered Expression	[1019]
TPBG	TT70MLA	Strong	Biomarker	[1020]
TPH1	TTZSJHV	Strong	Biomarker	[1021]
TPP1	TTOVYPT	Strong	Genetic Variation	[1022]
TPT1	TT3PTB6	Strong	Altered Expression	[1023]
TPX2	TT0PHL4	Strong	Biomarker	[1024]
TRAF6	TTCDR6M	Strong	Biomarker	[374]
TREM1	TTHZQP0	Strong	Biomarker	[1025]
TREM2	TTQRMSJ	Strong	Biomarker	[1026]
TRIM24	TT9Q7AE	Strong	Altered Expression	[1027]
TRIM27	TTTO3QN	Strong	Biomarker	[1028]
TRIM28	TTQ2BKV	Strong	Biomarker	[215]
TRIM37	TTAMCSL	Strong	Altered Expression	[1029]
TRIM59	TT613U4	Strong	Altered Expression	[1030]
TRIP10	TTKHTGE	Strong	Altered Expression	[1031]
TRPC5	TT32NQ1	Strong	Altered Expression	[1032]
TRPC6	TTRBT3W	Strong	Genetic Variation	[215]
TRPM4	TTJ2HKA	Strong	Biomarker	[1033]
TRPM7	TTFPVZO	Strong	Biomarker	[1034]
TRPV6	TTBK14N	Strong	Altered Expression	[455]
TTK	TTP7EGM	Strong	Altered Expression	[1035]
TXN	TTZJ5U9	Strong	Biomarker	[1036]
TXNIP	TTTLDZK	Strong	Altered Expression	[1037]
TXNRD1	TTR7UJ3	Strong	Biomarker	[1038]
TYMP	TTO0IB8	Strong	Altered Expression	[1039]
TYRO3	TTIEMFN	Strong	Altered Expression	[1040]
TYRP1	TTFRV98	Strong	Genetic Variation	[1041]
UCHL5	TTSX29Z	Strong	Altered Expression	[1042]
UCP2	TTSC2YM	Strong	Biomarker	[1043]
UGT1A1	TT34ZAF	Strong	Genetic Variation	[1044]
UMPS	TTAFJUD	Strong	Altered Expression	[1045]
USP1	TTG9MT5	Strong	Posttranslational Modification	[194]
USP13	TTVJIO2	Strong	Biomarker	[1046]
USP14	TTVSYP9	Strong	Genetic Variation	[356]
USP2	TTUEQ1W	Strong	Biomarker	[1047]
USP44	TTJLTNM	Strong	Altered Expression	[1048]
USP5	TTGYTMA	Strong	Altered Expression	[1049]
USP7	TTXU3EQ	Strong	Altered Expression	[1050]
UTRN	TTNO1VA	Strong	Posttranslational Modification	[1051]
UTS2R	TTW5UDX	Strong	Genetic Variation	[1052]
VANGL1	TT18WJB	Strong	Biomarker	[1053]
VCAM1	TTHCEF6	Strong	Biomarker	[1054]
VDAC1	TTAMKGB	Strong	Altered Expression	[1055]
VEGFB	TTPJQHE	Strong	Biomarker	[1056]
VEGFC	TT0QUFV	Strong	Biomarker	[1056]
VEGFD	TTOM5H4	Strong	Altered Expression	[1057]
VIP	TTGTWLF	Strong	Altered Expression	[1058]
VIPR1	TTCL30I	Strong	Biomarker	[1059]
VTCN1	TTCK85E	Strong	Altered Expression	[1060]
WDR5	TT7OFWB	Strong	Biomarker	[1061]
WNK1	TTJ9UMX	Strong	Biomarker	[755]
WRN	TT2H5WQ	Strong	Altered Expression	[1062]
WWP1	TTBWMKT	Strong	Biomarker	[1063]
XIAP	TTK3WBU	Strong	Altered Expression	[1064]
XPA	TTGT87E	Strong	Genetic Variation	[1065]
XRCC5	TTCB9KW	Strong	Biomarker	[1066]
ZEB2	TTT2WK4	Strong	Biomarker	[1067]
ABCB11	TTUXCAF	Definitive	Biomarker	[1068]
ABCC8	TTP835K	Definitive	Biomarker	[1068]
ABCG1	TTMWDGU	Definitive	Biomarker	[1068]
ACAT1	TTK3C21	Definitive	Biomarker	[1069]
ADH7	TT3LE7P	Definitive	Genetic Variation	[1070]
CCR3	TTD3XFU	Definitive	Biomarker	[1071]
CHUK	TT1F8OQ	Definitive	Altered Expression	[1072]
CTSS	TTUMQVO	Definitive	Biomarker	[1073]
DTL	TT8396I	Definitive	Altered Expression	[1074]
ENPP1	TTZTIWS	Definitive	Genetic Variation	[1075]
ETS2	TT9AH0M	Definitive	Biomarker	[1076]
FECH	TTQ6VF4	Definitive	Altered Expression	[1077]
FKBP10	TT4P8O2	Definitive	Altered Expression	[1078]
GABRA1	TT1MPAY	Definitive	Posttranslational Modification	[1079]
GAD2	TT7UY6K	Definitive	Biomarker	[1080]
GADD45B	TTMDW9L	Definitive	Biomarker	[1081]
GALR1	TTX3HNZ	Definitive	Biomarker	[1082]
GJD2	TTOZAFI	Definitive	Biomarker	[580]
GJD3	TT7C18W	Definitive	Posttranslational Modification	[580]
KDM2A	TT8XTY2	Definitive	Biomarker	[1083]
KLK1	TT5T3P6	Definitive	Altered Expression	[1084]
LANCL1	TTZW8NS	Definitive	Biomarker	[1085]
MMP15	TTNSTO3	Definitive	Biomarker	[1086]
PPOX	TTNFMS9	Definitive	Biomarker	[1083]
SLC6A8	TTYUHB5	Definitive	Genetic Variation	[1087]
TACR1	TTZPO1L	Definitive	Genetic Variation	[1088]
TACR2	TTYO0A3	Definitive	Genetic Variation	[1088]
TNFRSF17	TTZ3P4W	Definitive	Genetic Variation	[1089]
TXNRD3	TTDYFVB	Definitive	Biomarker	[1090]
ZAP70	TTUMHT8	Definitive	Altered Expression	[1091]

This Disease Is Related to 48 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
ABCC10	DTPS120	Limited	Biomarker	[1092]
SLC16A7	DTLT3UG	Limited	Biomarker	[1093]
SLC25A24	DTVAEDK	Limited	Biomarker	[1094]
SLC31A1	DTP8L4F	Limited	Genetic Variation	[1095]
SLC52A1	DT7NOKR	Limited	Biomarker	[1096]
SLC5A8	DTE3TAW	Limited	Biomarker	[1097]
SLC14A2	DT8QC7K	Disputed	Altered Expression	[1098]
SLC22A4	DT2EG60	moderate	Genetic Variation	[1099]
SLC22A5	DT3HUVD	moderate	Genetic Variation	[1100]
SLC25A22	DTJCWP8	moderate	Biomarker	[1101]
ABCB5	DTKVEXO	Strong	Biomarker	[205]
ABCB6	DTF9Y2V	Strong	Biomarker	[1102]
ABCC5	DTYVM24	Strong	Altered Expression	[120]
ANXA11	DTGQ2CF	Strong	Biomarker	[1103]
SLC17A9	DT9BI8W	Strong	Biomarker	[1104]
SLC18A1	DTM953D	Strong	Genetic Variation	[1105]
SLC25A13	DTDSYAQ	Strong	Biomarker	[1106]
SLC25A20	DTQOUM4	Strong	Biomarker	[385]
SLC25A21	DT2UQYR	Strong	Altered Expression	[1107]
SLC25A26	DT8HR5O	Strong	Genetic Variation	[215]
SLC25A3	DTCRIWV	Strong	Genetic Variation	[1108]
SLC26A3	DTN1FMD	Strong	Biomarker	[1109]
SLC29A2	DTW78DQ	Strong	Biomarker	[936]
SLC2A3	DT9SQ3L	Strong	Genetic Variation	[1110]
SLC30A9	DT2I79L	Strong	Altered Expression	[1111]
SLC35A2	DT0567K	Strong	Biomarker	[1112]
SLC36A4	DTBS49U	Strong	Biomarker	[1113]
SLC37A1	DTH9SQJ	Strong	Biomarker	[1114]
SLC39A14	DTZ6IJW	Strong	Biomarker	[1115]
SLC39A7	DTDQSAM	Strong	Altered Expression	[1116]
SLC39A8	DTLPQGT	Strong	Altered Expression	[1117]
SLC4A1	DTB0Q3P	Strong	Altered Expression	[1118]
SLC4A4	DTWDEIL	Strong	Biomarker	[1119]
SLC6A18	DTGQ7FH	Strong	Genetic Variation	[215]
SLC6A6	DTHWCVA	Strong	Biomarker	[1120]
SLC7A2	DTWY9RT	Strong	Genetic Variation	[1121]
SLC9A9	DT8LP62	Strong	Altered Expression	[1122]
ABCA10	DTVU0E3	Definitive	Biomarker	[1068]
ABCA12	DT7LDG0	Definitive	Biomarker	[1068]
ABCA3	DT2T6VQ	Definitive	Biomarker	[1068]
ABCA5	DT195NK	Definitive	Biomarker	[1068]
ABCA6	DTLMZUF	Definitive	Biomarker	[1068]
ABCA8	DT9NXMV	Definitive	Biomarker	[1068]
ABCA9	DTE3V8W	Definitive	Biomarker	[1068]
ABCC6	DT582KR	Definitive	Biomarker	[1068]
ABCD2	DT4MBHD	Definitive	Biomarker	[1068]
ABCD3	DTGLZO4	Definitive	Biomarker	[1068]
ABCD4	DTI8AFW	Definitive	Biomarker	[1068]

This Disease Is Related to 80 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
ACP3	DEDW5H6	Limited	Biomarker	[129]
AKR7A2	DE4G629	Limited	Genetic Variation	[1123]
ASNS	DEXISVQ	Limited	Biomarker	[357]
FMO3	DEP76YL	Limited	Genetic Variation	[1124]
GALK1	DE3OP9S	Limited	Biomarker	[1125]
HINT1	DEWJATF	Limited	Biomarker	[1126]
HSD17B7	DEDMWFX	Limited	Altered Expression	[622]
MANBA	DEMH6UB	Limited	Genetic Variation	[1127]
ME1	DE97WM8	Limited	Altered Expression	[1128]
MGST1	DEAPJSO	Limited	Genetic Variation	[1129]
PTGDS	DER3H9C	Limited	Biomarker	[1130]
SAT1	DEMWO83	Limited	Biomarker	[1131]
SI	DE5EO4Y	Limited	Altered Expression	[1132]
SULT1E1	DESTKG6	Limited	Biomarker	[1133]
SULT2A1	DE0P6LK	Limited	Genetic Variation	[1134]
UGT1A10	DEL5N6Y	Limited	Genetic Variation	[1135]
UGT2B7	DEB3CV1	Limited	Genetic Variation	[1136]
GSTO2	DEHMPZR	Disputed	Genetic Variation	[1137]
NT5C	DE4E31Z	Disputed	Biomarker	[1138]
ACP5	DESITDW	moderate	Biomarker	[1139]
CHDH	DEAHED0	moderate	Biomarker	[1140]
CRMP1	DE0EUXB	moderate	Posttranslational Modification	[1051]
PCYT1A	DEQYXD4	moderate	Altered Expression	[1141]
PSAT1	DEBS17P	moderate	Biomarker	[1131]
ACSS2	DEE76VW	Strong	Genetic Variation	[1142]
ADHFE1	DE8RJ3F	Strong	Posttranslational Modification	[1143]
AKR1A1	DED2FW3	Strong	Biomarker	[1144]
AKR1B10	DEP6GT1	Strong	Altered Expression	[1145]
ALDH1B1	DEXI4UQ	Strong	Genetic Variation	[1146]
APRT	DE2MV1R	Strong	Altered Expression	[777]
BAAT	DERA3OF	Strong	Biomarker	[1147]
CES2	DETHCPD	Strong	Altered Expression	[1148]
CHAC2	DEB4JZV	Strong	Altered Expression	[1149]
CMPK1	DEMPH4I	Strong	Biomarker	[1150]
CPA4	DEXKD7J	Strong	Biomarker	[1151]
CYP2S1	DE6NMGO	Strong	Biomarker	[1152]
CYP4F3	DEFCMPI	Strong	Genetic Variation	[1153]
CYP7A1	DEDZRQ1	Strong	Genetic Variation	[1154]
CYP7B1	DE36TMY	Strong	Altered Expression	[476]
EGLN3	DEMQTKH	Strong	Biomarker	[1155]
FAAH	DEUM1EX	Strong	Biomarker	[1156]
FADS1	DE05S8C	Strong	Genetic Variation	[1157]
FMO5	DEBMX7C	Strong	Altered Expression	[1158]
GALM	DE63NYG	Strong	Biomarker	[1159]
GCLC	DESYL1F	Strong	Biomarker	[576]
GGCT	DEKW6PB	Strong	Biomarker	[1160]
GLS	DE3E0VT	Strong	Altered Expression	[1161]
GMDS	DE8K7F3	Strong	Genetic Variation	[1162]
GSTA4	DEH7XYP	Strong	Biomarker	[1163]
HIF1AN	DEY1CBW	Strong	Altered Expression	[1164]
HK1	DEDMAGE	Strong	Biomarker	[1165]
HPGD	DEHKSC6	Strong	Altered Expression	[26]
MARS1	DE0K52I	Strong	Biomarker	[1166]
MAT1A	DEQ6NC9	Strong	Biomarker	[467]
MAT2B	DEKF1OH	Strong	Biomarker	[1167]
MTRR	DE6NIY9	Strong	Genetic Variation	[1168]
NAT10	DEZV4AP	Strong	Altered Expression	[1169]
PARK7	DEPOVCH	Strong	Biomarker	[1170]
PCK1	DEPLH5Z	Strong	Biomarker	[482]
PER1	DE9HF0I	Strong	Altered Expression	[1171]
PON3	DETXQZ1	Strong	Biomarker	[1172]
PRODH	DEVJIHS	Strong	Biomarker	[1173]
SMOX	DEOH5V3	Strong	Altered Expression	[1174]
THOP1	DE95LJC	Strong	Biomarker	[1175]
UCK2	DETN1O0	Strong	Biomarker	[1176]
UGT1A4	DELOY3P	Strong	Genetic Variation	[1135]
UGT1A7	DEZO4N3	Strong	Genetic Variation	[1135]
UGT1A8	DE2GB8N	Strong	Genetic Variation	[1135]
UGT1A9	DE85D2P	Strong	Genetic Variation	[1177]
UGT2B15	DENZ6B1	Strong	Genetic Variation	[1178]
UGT2B17	DEAZDL8	Strong	Genetic Variation	[1179]
UGT2B28	DEB7I4M	Strong	Biomarker	[1179]
UPP1	DEFZWAX	Strong	Altered Expression	[1180]
UPRT	DE20ETR	Strong	Biomarker	[1181]
AKR1C1	DE7P2FB	Definitive	Posttranslational Modification	[1182]
CHPF2	DEBH7ND	Definitive	Altered Expression	[1183]
CYP3A7	DERD86B	Definitive	Genetic Variation	[1075]
PGM1	DEA3VM1	Definitive	Biomarker	[1083]
PMM2	DEBRX3L	Definitive	Biomarker	[1083]
SULT2B1	DEZBN53	Definitive	Biomarker	[1184]

This Disease Is Related to 2313 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ACTR2	OT3C8U5T	Limited	Biomarker	[1185]
ADAM23	OTVWT6JZ	Limited	Posttranslational Modification	[1186]
ADAM28	OT3GBVHL	Limited	Altered Expression	[1187]
ADRM1	OTOU4EY6	Limited	Altered Expression	[1188]
AFAP1	OTR473H8	Limited	Biomarker	[1189]
AGO2	OT4JY32Q	Limited	Biomarker	[1190]
AIP	OTDJ3OSV	Limited	Genetic Variation	[1191]
AKAP9	OT7Z2YRP	Limited	Altered Expression	[1192]
ALOX15B	OTWQQ08W	Limited	Biomarker	[1193]
ALX3	OTXZ25PZ	Limited	Biomarker	[1194]
ANAPC1	OT2YY35L	Limited	Biomarker	[1094]
ANGPTL1	OTXIN6V5	Limited	Altered Expression	[1195]
ANKRD1	OTHJ7JV9	Limited	Posttranslational Modification	[1196]
ANXA3	OTDD8OI7	Limited	Biomarker	[1197]
APOBEC1	OTY8QX2R	Limited	Biomarker	[1198]
ARC	OTN2QQPG	Limited	Biomarker	[1199]
ARHGAP15	OT9CKHDC	Limited	Altered Expression	[1200]
ARHGAP8	OT19H5Q9	Limited	Genetic Variation	[1201]
ARHGEF7	OT9BPJCL	Limited	Biomarker	[1202]
ARID1A	OTRWDV3P	Limited	Genetic Variation	[1203]
ARL6IP5	OTYZ6BEQ	Limited	Biomarker	[1204]
ARL6IP6	OT2OU9R2	Limited	Altered Expression	[1205]
ARR3	OTRZ00CH	Limited	Biomarker	[785]
ASAP2	OTGEXULW	Limited	Genetic Variation	[193]
ASPN	OTYJM80N	Limited	Biomarker	[1206]
ATAD1	OTJ02XFL	Limited	Genetic Variation	[1207]
ATOH1	OTBZYG2R	Limited	Biomarker	[1208]
ATP11A	OT7M9ZDK	Limited	Biomarker	[1209]
ATP6AP2	OT0IABVV	Limited	Biomarker	[1210]
ATP6V0A1	OT1IK0KA	Limited	Altered Expression	[1211]
ATP6V0C	OTKPL09B	Limited	Biomarker	[1212]
AZIN2	OT8OB7CG	Limited	Biomarker	[1213]
B4GALT1	OTBCXEK7	Limited	Genetic Variation	[1214]
BAG1	OTRQNIA4	Limited	Biomarker	[1215]
BCAP31	OTKSACR4	Limited	Altered Expression	[1216]
BCL2L11	OTNQQWFJ	Limited	Biomarker	[1217]
BEX2	OT4G5SIC	Limited	Biomarker	[733]
BTG3	OT9ANHVT	Limited	Altered Expression	[1218]
BVES	OT4GT1WC	Limited	Altered Expression	[1219]
BZW2	OTBT0A1B	Limited	Altered Expression	[1220]
C12orf75	OTFVI3EY	Limited	Altered Expression	[1221]
C2orf68	OTNNFK6R	Limited	Biomarker	[1222]
CADPS	OTAJF6QN	Limited	Biomarker	[1223]
CAMTA1	OTAN1S5B	Limited	Biomarker	[1224]
CARD8	OTXXZYWU	Limited	Biomarker	[1225]
CAST	OTBXZZGF	Limited	Altered Expression	[1226]
CAV2	OT1FGRQX	Limited	Posttranslational Modification	[1227]
CBFA2T2	OTNOIB23	Limited	Biomarker	[1202]
CBFB	OTIAC6W4	Limited	Biomarker	[1228]
CBY1	OTAKMUS2	Limited	Biomarker	[1229]
CCDC34	OTZ3AGSQ	Limited	Biomarker	[1230]
CCL7	OTDIS99H	Limited	Biomarker	[411]
CCND2	OTDULQF9	Limited	Genetic Variation	[364]
CCT3	OTL6EOS1	Limited	Biomarker	[1231]
CCT5	OTPZ38BT	Limited	Biomarker	[1231]
CCT6A	OTCYWL5F	Limited	Altered Expression	[1232]
CCT7	OTQNM3CY	Limited	Biomarker	[1231]
CD164	OTZ7FIU8	Limited	Altered Expression	[1233]
CD177	OTS79FNF	Limited	Biomarker	[1234]
CD247	OT45FGUX	Limited	Biomarker	[1235]
CDC73	OT6JASZ1	Limited	Biomarker	[1236]
CDH15	OTJ1TO02	Limited	Biomarker	[1237]
CDH17	OT9EV2XK	Limited	Biomarker	[1238]
CDK2AP2	OTR99SJ8	Limited	Posttranslational Modification	[1239]
CEACAM4	OT0C7YUD	Limited	Altered Expression	[1240]
CELF2	OTLJJ4VT	Limited	Biomarker	[1241]
CEP55	OTGSG2PA	Limited	Altered Expression	[1242]
CIAPIN1	OTWS90F9	Limited	Altered Expression	[1243]
CKB	OTUCKOTT	Limited	Biomarker	[1244]
CLC	OTYMYR85	Limited	Genetic Variation	[1245]
CLDN12	OTO55YZI	Limited	Altered Expression	[1246]
CMAS	OTFQJG3C	Limited	Altered Expression	[1247]
CNGB1	OTA5DE38	Limited	Biomarker	[105]
CNOT7	OTJBKCPI	Limited	Biomarker	[1248]
COL5A2	OT5VOSQE	Limited	Altered Expression	[1249]
CRIP2	OTVVJSYX	Limited	Biomarker	[1250]
CRYGC	OTYSTQWI	Limited	Biomarker	[1251]
CSRP1	OTUS7RM2	Limited	Biomarker	[1252]
CST7	OTQWZUVQ	Limited	Biomarker	[1253]
CTAG1B	OTIQGW6U	Limited	Altered Expression	[44]
CTAG2	OT8HISP4	Limited	Altered Expression	[1254]
CTHRC1	OTV88X2G	Limited	Biomarker	[1255]
CTNNBIP1	OTX9SBJG	Limited	Altered Expression	[1256]
CUL2	OTPF83PG	Limited	Genetic Variation	[1257]
CUL4A	OTTBV70J	Limited	Biomarker	[1258]
CXADR	OT9ZP02A	Limited	Biomarker	[785]
CXCL3	OTSL94KH	Limited	Altered Expression	[1259]
CXCL6	OTFTCQ4O	Limited	Altered Expression	[1260]
DAPK1	OTNCNUCO	Limited	Altered Expression	[1261]
DBNL	OTT2OQOV	Limited	Biomarker	[1253]
DDX27	OT64NCZ6	Limited	Altered Expression	[1262]
DDX56	OTGURA53	Limited	Altered Expression	[1263]
DDX6	OTKWXVDY	Limited	Biomarker	[1264]
DECR1	OTCDIR6X	Limited	Altered Expression	[1265]
DESI1	OTFNIW98	Limited	Biomarker	[1266]
DLC1	OTP8LMCR	Limited	Altered Expression	[1267]
DNAAF4	OTVDYBJE	Limited	Biomarker	[1268]
DNAJC3	OT7ROIJF	Limited	Biomarker	[1204]
DSC3	OTYG47F8	Limited	Biomarker	[1269]
DUSP2	OTH54FMR	Limited	Altered Expression	[1270]
DVL2	OTMNYNCM	Limited	Genetic Variation	[1271]
E2F4	OTB3JFH4	Limited	Genetic Variation	[1272]
ECT2	OTQDUCT6	Limited	Biomarker	[1273]
EEF2	OTZ7SZ39	Limited	Genetic Variation	[1274]
EFNA1	OTU2NUA2	Limited	Genetic Variation	[1275]
EFNB1	OT7JJW8P	Limited	Biomarker	[1276]
EGR2	OTAVQ78J	Limited	Genetic Variation	[1277]
EIF3G	OT5L1SRY	Limited	Biomarker	[1278]
EIF4A3	OTYYFE7K	Limited	Biomarker	[1279]
ELK4	OTVSSEOE	Limited	Altered Expression	[516]
ENC1	OTJEUB6U	Limited	Biomarker	[1280]
EP400	OTVQ75NX	Limited	Altered Expression	[1281]
ESRP1	OTNCS4SL	Limited	Biomarker	[1282]
FADD	OTV7GFHH	Limited	Biomarker	[1283]
FAH	OTGZA1YR	Limited	Biomarker	[8]
FANCD2	OTVEB5LF	Limited	Altered Expression	[1284]
FAT4	OT7QONNV	Limited	Biomarker	[1285]
FBXO8	OTZNGJGW	Limited	Biomarker	[1286]
FCGR2C	OTNLMNYB	Limited	Biomarker	[66]
FCGR3B	OTSLSPZG	Limited	Biomarker	[66]
FEN1	OT6QGG7O	Limited	Genetic Variation	[1287]
FGF13	OTHNNVSG	Limited	Biomarker	[1288]
FGF3	OT9PK2SI	Limited	Genetic Variation	[1289]
FILIP1L	OTPY8IMS	Limited	Biomarker	[1290]
FOXA2	OTJOCVOY	Limited	Altered Expression	[82]
FUT6	OTBZUQ7F	Limited	Altered Expression	[905]
FUT7	OTJF6BSN	Limited	Biomarker	[1291]
FZD1	OTZATHVS	Limited	Altered Expression	[1219]
FZD5	OTXFFY56	Limited	Altered Expression	[1219]
GADL1	OTJM4A0R	Limited	Biomarker	[1292]
GAGE7	OTF8BTR9	Limited	Posttranslational Modification	[1293]
GATA5	OTO81B63	Limited	Biomarker	[1294]
GCNT1	OTF6OC66	Limited	Altered Expression	[1295]
GCNT7	OTB0M0TT	Limited	Altered Expression	[1295]
GFI1	OT9HB9H8	Limited	Altered Expression	[1296]
GGA2	OT43HO27	Limited	Altered Expression	[1297]
GML	OTHKIB62	Limited	Altered Expression	[1298]
GNAS	OTMH8BKJ	Limited	Genetic Variation	[294]
GOLGA2	OT5S9KYM	Limited	Altered Expression	[1299]
GPX2	OTXI2NTI	Limited	Biomarker	[1300]
GRHL1	OTZ4MNEW	Limited	Altered Expression	[1301]
GSTT2	OTANW3TJ	Limited	Genetic Variation	[1302]
GUCA2A	OTUSF75G	Limited	Biomarker	[1303]
GYPA	OTABU4YV	Limited	Genetic Variation	[1304]
H3-3B	OT9XHQ3C	Limited	Biomarker	[1245]
HACE1	OTEZULKD	Limited	Biomarker	[1305]
HFM1	OTHV3EFE	Limited	Altered Expression	[1306]
HGD	OTTKLQOO	Limited	Biomarker	[1307]
HGS	OTCYYCAC	Limited	Biomarker	[1308]
HIC1	OTI9TWY4	Limited	Biomarker	[1309]
HNRNPD	OT5UO1FA	Limited	Altered Expression	[1299]
HOMER2	OT4JGKJF	Limited	Biomarker	[1194]
HOXA4	OTNVTQDT	Limited	Biomarker	[1310]
HOXB7	OTC7WYU8	Limited	Biomarker	[1311]
HOXD10	OT0NOWU2	Limited	Biomarker	[1310]
HOXD3	OTBUZ35T	Limited	Biomarker	[1312]
HPX	OT14T7Q1	Limited	Biomarker	[1313]
HRK	OTR4GWJ0	Limited	Posttranslational Modification	[1314]
HS3ST2	OTWFA0GJ	Limited	Biomarker	[1315]
HTN3	OTEUXA81	Limited	Genetic Variation	[1134]
HYOU1	OTBGBSOV	Limited	Altered Expression	[1316]
ID4	OTPMJ39I	Limited	Posttranslational Modification	[1317]
IFITM1	OTECO1G8	Limited	Biomarker	[1318]
IGF2BP1	OT9G360P	Limited	Biomarker	[1319]
IGF2BP2	OT4ZSEEE	Limited	Biomarker	[1320]
IKZF1	OTCW1FKL	Limited	Biomarker	[371]
IL17RA	OTVVI8ER	Limited	Biomarker	[1321]
IL17RC	OTEFOBSS	Limited	Genetic Variation	[1321]
IL2RG	OTRZ3OMY	Limited	Biomarker	[30]
ILF3	OTKMZ5K5	Limited	Altered Expression	[1322]
IMMT	OTBDSLE7	Limited	Biomarker	[327]
INCENP	OT9HFRYK	Limited	Altered Expression	[1323]
INPP4B	OTLROA7G	Limited	Biomarker	[1324]
INTS2	OT2N5TCK	Limited	Genetic Variation	[1289]
IPO7	OTDFMQ00	Limited	Altered Expression	[1325]
IQGAP3	OT4RZV2M	Limited	Altered Expression	[1326]
ITGB4	OT28UK84	Limited	Posttranslational Modification	[1327]
ITGBL1	OTJDHE17	Limited	Biomarker	[1328]
IVD	OT8JFXUQ	Limited	Biomarker	[1329]
KAT5	OTL7257A	Limited	Altered Expression	[1330]
KDM4B	OT5P1UPY	Limited	Biomarker	[1331]
KHSRP	OTDHZARB	Limited	Altered Expression	[1332]
KIR3DL1	OTPOSXFX	Limited	Biomarker	[71]
KLF12	OTVH4KD4	Limited	Biomarker	[1333]
KLF17	OT5NWVP7	Limited	Altered Expression	[1334]
KRT5	OTVGI9HT	Limited	Biomarker	[1335]
LAMB1	OT6J9LJR	Limited	Biomarker	[1336]
LAMTOR2	OTHEDISB	Limited	Posttranslational Modification	[1239]
LDHB	OT9B1CT3	Limited	Biomarker	[1337]
LIN28B	OTVWP0FN	Limited	Biomarker	[659]
LLGL1	OTAIQSXZ	Limited	Altered Expression	[1338]
LOXL4	OT6XY2JL	Limited	Biomarker	[1339]
LTBP2	OTS88GSD	Limited	Altered Expression	[1340]
LY6G6D	OTG75QOC	Limited	Altered Expression	[667]
LYPD5	OTGP7UKA	Limited	Biomarker	[1341]
MAP2K4	OTZPZX11	Limited	Genetic Variation	[1342]
MARCKSL1	OT13J2FM	Limited	Altered Expression	[1343]
MBNL1	OTOV7J85	Limited	Biomarker	[1344]
MCAT	OTH07FIW	Limited	Biomarker	[39]
MCTS1	OT7SAOJP	Limited	Biomarker	[39]
MEIS2	OTG4ADLM	Limited	Biomarker	[1345]
MFSD13A	OTP306N2	Limited	Biomarker	[1346]
MGP	OTZWU3FU	Limited	Altered Expression	[893]
MICB	OTS2DVDW	Limited	Genetic Variation	[1347]
MID1	OTWN1PGU	Limited	Biomarker	[106]
MINDY4	OTBZ2SZB	Limited	Altered Expression	[348]
MLXIPL	OTR9MLLW	Limited	Biomarker	[1348]
MMP23B	OT2OR6TS	Limited	Biomarker	[115]
MOB4	OTOQRMAS	Limited	Altered Expression	[1349]
MPEG1	OT7DAO0F	Limited	Altered Expression	[1035]
MRPS30	OTDXIAGG	Limited	Genetic Variation	[193]
MSX2	OT1WDKE1	Limited	Biomarker	[1350]
MTA3	OTIA6C79	Limited	Biomarker	[1351]
MTMR3	OTBIT23O	Limited	Genetic Variation	[1352]
MTO1	OT7HCZ1D	Limited	Biomarker	[1353]
MTPAP	OT6HQ02S	Limited	Genetic Variation	[193]
MUC12	OTYDC13T	Limited	Altered Expression	[1354]
MUC13	OTWKS9MF	Limited	Biomarker	[1355]
MVP	OTJGHJRB	Limited	Biomarker	[1356]
MXD1	OTS5CTHX	Limited	Biomarker	[1357]
MXI1	OTUQ9E0D	Limited	Genetic Variation	[1358]
MYEOV	OTDC7UHL	Limited	Altered Expression	[1359]
MYH11	OTVNVWY3	Limited	Genetic Variation	[1360]
MYO18B	OTGYY4NK	Limited	Biomarker	[1361]
MYO3A	OTPM8PHS	Limited	Genetic Variation	[43]
MYOD1	OTV2S79X	Limited	Posttranslational Modification	[1362]
NAA10	OTYB9R6I	Limited	Altered Expression	[1363]
NAA40	OTFLRVQO	Limited	Altered Expression	[146]
NAP1L1	OTI7WBZV	Limited	Altered Expression	[1364]
NDE1	OT2N8Q17	Limited	Biomarker	[1365]
NECTIN1	OTTE5ZR6	Limited	Altered Expression	[1366]
NEUROD1	OTZQ7QJ2	Limited	Biomarker	[1367]
NEUROG1	OTMJZP9G	Limited	Posttranslational Modification	[1368]
NHEJ1	OTYOO05J	Limited	Biomarker	[1369]
NKD1	OTY3MO97	Limited	Biomarker	[1370]
NKX2-3	OTF4IL5J	Limited	Biomarker	[1371]
NLRP2	OTJA81JU	Limited	Genetic Variation	[1372]
NME4	OT2JTT42	Limited	Altered Expression	[1373]
NOL3	OT1K0L0D	Limited	Altered Expression	[1374]
NOLC1	OTKDZU0D	Limited	Biomarker	[1375]
NPRL2	OTOB10MO	Limited	Biomarker	[1376]
NPTX1	OTKVHCV0	Limited	Biomarker	[1194]
NR2F6	OTNVO2B6	Limited	Altered Expression	[1377]
NRL	OT65MFKQ	Limited	Biomarker	[1356]
NUDT6	OTCS3NYZ	Limited	Biomarker	[1378]
NUPR1	OT4FU8C0	Limited	Biomarker	[1279]
OGT	OT1Z1ZXE	Limited	Biomarker	[479]
ONECUT2	OTHUE5YY	Limited	Genetic Variation	[1379]
ORM2	OTRJGZP8	Limited	Biomarker	[1380]
OTX1	OTRGSGH9	Limited	Biomarker	[1381]
P4HB	OTTYNYPF	Limited	Biomarker	[864]
PAF1	OTDDGUBQ	Limited	Biomarker	[1382]
PAGE4	OT2VLWT0	Limited	Altered Expression	[1383]
PAPOLA	OTPHD65D	Limited	Genetic Variation	[193]
PARD3B	OTGZ43YI	Limited	Altered Expression	[1384]
PCDH10	OT2GIT0E	Limited	Biomarker	[1385]
PCNT	OTW4Z65J	Limited	Biomarker	[105]
PDAP1	OTJSWMOD	Limited	Genetic Variation	[193]
PDHX	OTG7O271	Limited	Biomarker	[139]
PDIK1L	OTISF4KG	Limited	Biomarker	[1386]
PDLIM5	OTLQVV22	Limited	Genetic Variation	[1387]
PDSS1	OTXGVHAB	Limited	Altered Expression	[1388]
PEA15	OTKCKTSX	Limited	Biomarker	[1389]
PEAK1	OTVVM637	Limited	Altered Expression	[589]
PGAM1	OTZ5DB06	Limited	Altered Expression	[1390]
PGM5	OTEAS7OC	Limited	Altered Expression	[1391]
PGP	OT6QQ7OR	Limited	Genetic Variation	[1124]
PIK3C3	OTLUM9L7	Limited	Altered Expression	[1392]
PITX2	OTWMXAOY	Limited	Posttranslational Modification	[1393]
PLA2G10	OTRZ2L5A	Limited	Altered Expression	[1394]
PLA2G15	OT6VJTPA	Limited	Biomarker	[1395]
PLS3	OTYBM4PK	Limited	Genetic Variation	[1396]
PNO1	OT010GIS	Limited	Biomarker	[1397]
PNPLA2	OTR3ERMR	Limited	Biomarker	[1398]
POFUT1	OTOBJZIT	Limited	Biomarker	[1399]
POLK	OTKZ38JH	Limited	Biomarker	[1066]
POLL	OTZ24QGM	Limited	Biomarker	[180]
POLQ	OTBHK0E6	Limited	Biomarker	[1066]
POLR1D	OTOCZQNA	Limited	Altered Expression	[1400]
POLR2F	OTF9T8I2	Limited	Altered Expression	[1211]
PPP1R11	OTSHYPPW	Limited	Biomarker	[1401]
PPP1R3A	OTJL9VYP	Limited	Genetic Variation	[1402]
PPP1R8	OTH5KB2P	Limited	Altered Expression	[1363]
PPP2R1B	OTFIHQGD	Limited	Biomarker	[1403]
PPP2R2B	OTSFVC82	Limited	Posttranslational Modification	[1404]
PRDM2	OT8L7CGX	Limited	Biomarker	[1405]
PRSS2	OTOMVUWL	Limited	Altered Expression	[1406]
PRSS50	OTC5JAVO	Limited	Altered Expression	[1407]
PTMA	OT2W4T1M	Limited	Biomarker	[1408]
RAB27B	OTPF9D0K	Limited	Biomarker	[1409]
RANBP9	OTM8COM5	Limited	Altered Expression	[1410]
RASAL1	OTAHUNN7	Limited	Altered Expression	[1411]
RASD2	OTETA815	Limited	Biomarker	[420]
RASSF5	OT6Q41I2	Limited	Biomarker	[1412]
RBBP8	OTRHJ3GI	Limited	Altered Expression	[1413]
RCN2	OTIU8JWD	Limited	Biomarker	[1414]
REST	OTLL92LQ	Limited	Altered Expression	[69]
RFC3	OT1MS7AO	Limited	Altered Expression	[1415]
RFC4	OTWALD2R	Limited	Biomarker	[1416]
RFX5	OT73KJ5P	Limited	Biomarker	[1417]
RGCC	OTYJMLWM	Limited	Altered Expression	[1418]
RHPN2	OTTYWMF6	Limited	Genetic Variation	[364]
RIN1	OTPBROUD	Limited	Biomarker	[1419]
RMC1	OT7K8MTJ	Limited	Biomarker	[1420]
RMI1	OT1ZVTFL	Limited	Biomarker	[1421]
RNF40	OTC8SDA3	Limited	Biomarker	[1422]
RNF41	OTN1DQOY	Limited	Altered Expression	[1423]
RPH3AL	OT9VFJEL	Limited	Biomarker	[1424]
RPL11	OT3VZ6OE	Limited	Genetic Variation	[1425]
RPL18	OTJCH62J	Limited	Altered Expression	[1426]
RPL19	OT33LM66	Limited	Altered Expression	[1427]
RPL22	OTVCN8K0	Limited	Genetic Variation	[1428]
RPL7A	OT6E6UKF	Limited	Altered Expression	[1429]
RPP14	OT4OYFSK	Limited	Posttranslational Modification	[1239]
RPS20	OTI8052R	Limited	Genetic Variation	[874]
RPS27	OTFXKY7P	Limited	Altered Expression	[1035]
RPS27A	OTIIGGZ2	Limited	Altered Expression	[1430]
RTCA	OTSJRVTD	Limited	Genetic Variation	[1379]
RTL8C	OTJA37NU	Limited	Genetic Variation	[1431]
RTN1	OTCX1SMK	Limited	Biomarker	[1432]
S100A10	OTI71243	Limited	Biomarker	[1433]
SARDH	OTQ49Q27	Limited	Biomarker	[1434]
SCRN1	OTELM5C2	Limited	Altered Expression	[1435]
SEC14L2	OTJST64D	Limited	Biomarker	[1436]
SECISBP2	OTBXUURJ	Limited	Biomarker	[1437]
SELENOP	OT02B8IR	Limited	Genetic Variation	[1437]
SEMA6A	OTDQ7QAW	Limited	Biomarker	[1438]
SEMG1	OT6Z4BPQ	Limited	Biomarker	[1439]
SEPTIN4	OTD16B30	Limited	Altered Expression	[1440]
SERPINA4	OTBK0GG7	Limited	Genetic Variation	[105]
SERPINB2	OT72QLZB	Limited	Biomarker	[1441]
SF3B6	OTPRKS6S	Limited	Posttranslational Modification	[1239]
SGCE	OT9F17JB	Limited	Biomarker	[1442]
SGMS1	OTZQE7PW	Limited	Altered Expression	[1349]
SHMT1	OTIINA3J	Limited	Biomarker	[421]
SHMT2	OT5NCAZN	Limited	Altered Expression	[1443]
SLC16A4	OT1YXBKC	Limited	Altered Expression	[925]
SLC35G1	OTKZUA8O	Limited	Biomarker	[1266]
SMAGP	OT57BZII	Limited	Altered Expression	[1444]
SMURF2	OT3TRVL7	Limited	Altered Expression	[1445]
SNCB	OTELSEK6	Limited	Altered Expression	[1446]
SND1	OTT734JN	Limited	Altered Expression	[1447]
SOCS6	OT2O5ZBK	Limited	Biomarker	[1448]
SOS1	OTTCWXC3	Limited	Biomarker	[1449]
SPANXA1	OTMK3QIS	Limited	Biomarker	[1383]
SPECC1	OTPEML48	Limited	Biomarker	[1432]
SPG7	OT8OY9ST	Limited	Biomarker	[785]
SPINK4	OTHTCW94	Limited	Altered Expression	[1450]
SPINT1	OT1CLR5L	Limited	Biomarker	[1451]
SPINT2	OTQV7BKQ	Limited	Altered Expression	[1452]
SPTAN1	OT6VY3A3	Limited	Biomarker	[1453]
ST3GAL4	OTNENJZQ	Limited	Altered Expression	[1454]
ST3GAL6	OTB17Q43	Limited	Biomarker	[1455]
STK17B	OT4NYNO8	Limited	Biomarker	[1456]
STN1	OT8UWRA3	Limited	Biomarker	[1457]
STXBP1	OTRYA8C3	Limited	Biomarker	[30]
SUSD6	OTZS4SKF	Limited	Altered Expression	[1458]
SUV39H2	OTU0F4LL	Limited	Altered Expression	[1459]
TAF1B	OTMZB09B	Limited	Biomarker	[1460]
TAS2R14	OTWA9CYC	Limited	Genetic Variation	[1461]
TCF21	OT393IMA	Limited	Biomarker	[1462]
TCF7L1	OTTUTF0O	Limited	Altered Expression	[1463]
TENM3	OTWY13GR	Limited	Biomarker	[1464]
TFAP4	OT1KQIUX	Limited	Biomarker	[1465]
TFDP1	OT6RZ7VT	Limited	Biomarker	[1466]
TFIP11	OT7NVSWU	Limited	Biomarker	[1467]
TGFBI	OTR443C5	Limited	Biomarker	[1468]
THUMPD1	OTKU8KWH	Limited	Genetic Variation	[173]
TIGAR	OTR7NMRJ	Limited	Biomarker	[1469]
TIMM8A	OTDX9687	Limited	Biomarker	[1470]
TMEM54	OTPQEFR0	Limited	Altered Expression	[1471]
TNFSF9	OTV9L89D	Limited	Altered Expression	[1472]
TNRC6A	OT493IOM	Limited	Biomarker	[1473]
TP63	OT0WOOKQ	Limited	Altered Expression	[882]
TPI1	OT14KP4B	Limited	Genetic Variation	[1474]
TPM1	OTD73X6R	Limited	Genetic Variation	[1475]
TRAT1	OTMPUNPD	Limited	Biomarker	[1476]
TRIM23	OTVIGJ4T	Limited	Altered Expression	[1363]
TRIM25	OT35SG1R	Limited	Biomarker	[396]
TRIM47	OTM9DGUD	Limited	Altered Expression	[1476]
TRMT9B	OTU3UPEE	Limited	Altered Expression	[1477]
TSPAN8	OT1F68WQ	Limited	Biomarker	[1478]
BEND4	OT7Z1422	Disputed	Posttranslational Modification	[1194]
BOLL	OT5FAEJJ	Disputed	Biomarker	[1479]
CABYR	OTKYMT99	Disputed	Biomarker	[1479]
CALB2	OTSNMCG9	Disputed	Altered Expression	[1480]
CDH7	OTQEXCKU	Disputed	Biomarker	[1481]
CDV3	OTUA175T	Disputed	Genetic Variation	[1482]
CETN1	OTGQ8JOZ	Disputed	Biomarker	[1480]
EIF4E3	OTTWVS2R	Disputed	Genetic Variation	[197]
EIF4EBP3	OTYY2WS5	Disputed	Biomarker	[197]
EIF4H	OTGZI072	Disputed	Altered Expression	[1483]
FLNC	OT3F8J6Y	Disputed	Biomarker	[1484]
GALNT15	OTVK9EHD	Disputed	Genetic Variation	[1485]
HOPX	OTBSR6C9	Disputed	Posttranslational Modification	[1486]
HOXD1	OTN4V9ZF	Disputed	Biomarker	[1479]
IFITM3	OT2QP8D3	Disputed	Altered Expression	[1487]
IL17B	OTS86H50	Disputed	Genetic Variation	[1488]
IL17RB	OT0KDNSF	Disputed	Biomarker	[1489]
JPH3	OTHTJO2I	Disputed	Biomarker	[1479]
KCNK12	OTFP82TK	Disputed	Posttranslational Modification	[1490]
KIF18A	OTSMBJ24	Disputed	Biomarker	[1491]
LDLRAP1	OT6QTX7R	Disputed	Biomarker	[1492]
MMUT	OTBBBV70	Disputed	Genetic Variation	[1493]
MRAS	OTNCVCQW	Disputed	Genetic Variation	[1482]
NOP56	OTT67SRZ	Disputed	Biomarker	[1494]
PRR15	OTJHSY8G	Disputed	Altered Expression	[1495]
RIPK3	OTL1D484	Disputed	Biomarker	[1496]
RNF111	OTO3QT6Q	Disputed	Biomarker	[1497]
RPS2	OTSMTZVB	Disputed	Biomarker	[1494]
RPS4X	OTIH80EK	Disputed	Altered Expression	[1498]
TAT	OT2CJ91O	Disputed	Biomarker	[1499]
TIPIN	OT9PZHXV	Disputed	Altered Expression	[1500]
ACSL1	OTB06ESI	moderate	Biomarker	[305]
ADAMTS12	OTG7HEA2	moderate	Posttranslational Modification	[1501]
ADAMTS3	OT2U6VF5	moderate	Biomarker	[202]
AGR3	OTONJPDP	moderate	Altered Expression	[1502]
AHSA1	OTC7AFHT	moderate	Biomarker	[203]
ANXA6	OT9KIQ0Y	moderate	Biomarker	[155]
ANXA7	OTLMD0TK	moderate	Biomarker	[1503]
ARHGAP25	OTYW7ED8	moderate	Altered Expression	[1504]
ARHGAP35	OTJ8POG0	moderate	Biomarker	[285]
ASS1	OT4ZMG0Q	moderate	Biomarker	[794]
ATG14	OTPZDKI0	moderate	Biomarker	[1505]
ATP5PF	OTDAE8FP	moderate	Biomarker	[1506]
BAG3	OTVXYUDQ	moderate	Biomarker	[1507]
BATF3	OTI61WXQ	moderate	Altered Expression	[1508]
BCCIP	OTFFKG79	moderate	Biomarker	[1509]
BUD23	OTJS7VU3	moderate	Biomarker	[1510]
CAPNS1	OT95EBBD	moderate	Biomarker	[1511]
CARD9	OTJ81AWD	moderate	Biomarker	[1512]
CBX8	OT4U5V1T	moderate	Biomarker	[427]
CCDC6	OTXRQDYG	moderate	Biomarker	[1513]
CCN3	OTOW5YL4	moderate	Biomarker	[1514]
CCT2	OTW1VV4E	moderate	Altered Expression	[74]
CD2AP	OTC76KQM	moderate	Biomarker	[1515]
CD63	OT2UGZA9	moderate	Biomarker	[487]
CD8A	OTDWQJXK	moderate	Biomarker	[1516]
CDC45	OT6NNLOD	moderate	Biomarker	[225]
CDC6	OTX93FE7	moderate	Biomarker	[1517]
CDCA3	OTUI8QK3	moderate	Biomarker	[1518]
CDCA5	OTZLCQ5U	moderate	Altered Expression	[1519]
CDKN3	OTBE3H07	moderate	Altered Expression	[1520]
CFAP45	OT8I8ZHH	moderate	Biomarker	[61]
CHST7	OT9HCUST	moderate	Posttranslational Modification	[1521]
CLCA4	OTCRR1M9	moderate	Biomarker	[1522]
CLDN3	OT71MN9S	moderate	Altered Expression	[1523]
COL12A1	OTHLTV53	moderate	Biomarker	[1524]
COPB2	OT82JIGC	moderate	Altered Expression	[1525]
COPS2	OTDSCPVV	moderate	Altered Expression	[1526]
CORO1A	OTVAZOHC	moderate	Biomarker	[1527]
CORO7	OTG7MEAJ	moderate	Biomarker	[1462]
CPEB3	OTP1GQCH	moderate	Altered Expression	[1528]
CPSF4	OT53UK5L	moderate	Biomarker	[1529]
CSMD1	OTIVDSC4	moderate	Genetic Variation	[1530]
CYTL1	OTLYUPUY	moderate	Biomarker	[1531]
DCAF15	OTWBXZ0E	moderate	Biomarker	[1489]
DCLRE1A	OT68PVSD	moderate	Biomarker	[1066]
DCLRE1C	OTW3KB1I	moderate	Biomarker	[1532]
DCP1A	OT3NCON3	moderate	Biomarker	[1533]
DDB2	OTO8HVVB	moderate	Altered Expression	[1534]
DERL2	OTI3TUUZ	moderate	Genetic Variation	[1535]
DLGAP5	OTWCN39U	moderate	Altered Expression	[1536]
DNAJA1	OT38BZQQ	moderate	Altered Expression	[225]
DND1	OTHLC8TA	moderate	Altered Expression	[1537]
DNER	OT2GH2E5	moderate	Biomarker	[1538]
DOCK2	OTZTS3PA	moderate	Biomarker	[1539]
E2F7	OTWW358N	moderate	Altered Expression	[1540]
EIF3J	OTJ4TAWK	moderate	Biomarker	[1541]
ERRFI1	OT7VZ2IZ	moderate	Altered Expression	[1332]
EXOSC8	OT75ACNG	moderate	Biomarker	[1542]
FBLN1	OT5MHHOP	moderate	Biomarker	[1543]
FEZF1	OTRX4NOT	moderate	Altered Expression	[1544]
FITM1	OTBKC6PT	moderate	Biomarker	[1545]
FMNL3	OTRP8R4W	moderate	Altered Expression	[1546]
FOXF1	OT2CJZ5K	moderate	Biomarker	[1547]
GAB1	OTQKE6V4	moderate	Biomarker	[1548]
GALNT14	OT9BSDDQ	moderate	Genetic Variation	[1549]
GBP2	OTVU4G07	moderate	Altered Expression	[1550]
GFRA1	OT3WBVYB	moderate	Biomarker	[237]
GFRA2	OT34CXNN	moderate	Biomarker	[237]
GNA12	OT3IRZH3	moderate	Altered Expression	[1551]
GPR42	OTEB0ROY	moderate	Biomarker	[103]
GPRC5A	OTPOCWR7	moderate	Altered Expression	[1552]
GRAP2	OTS5NIZ3	moderate	Biomarker	[203]
GTF2IRD1	OTEG9KU1	moderate	Biomarker	[993]
H4C1	OTB71W46	moderate	Altered Expression	[1553]
HAND2	OTCXYW4Y	moderate	Biomarker	[1554]
HHIP	OT77RQYS	moderate	Genetic Variation	[215]
HMGB3	OTCJ2EZY	moderate	Altered Expression	[1555]
HNRNPK	OTNPRM8U	moderate	Altered Expression	[1556]
HNRNPLL	OTA6Q5E0	moderate	Biomarker	[1557]
HOXA6	OTHJP8M2	moderate	Biomarker	[1558]
HYAL1	OT2SJN0X	moderate	Biomarker	[1559]
HYAL2	OTTVINXW	moderate	Biomarker	[1559]
IFIT2	OTI4EOAR	moderate	Altered Expression	[1560]
IFT20	OTKJS2BZ	moderate	Biomarker	[1561]
IL17C	OTKXIVNQ	moderate	Biomarker	[1562]
IL1F10	OTJAASGC	moderate	Biomarker	[1563]
IREB2	OT747D24	moderate	Altered Expression	[1564]
ITGA3	OTBCH21D	moderate	Biomarker	[1565]
ITGA7	OTTBTAYW	moderate	Altered Expression	[1566]
ITLN1	OT7ZLJVV	moderate	Genetic Variation	[1099]
KIDINS220	OTLBH2MA	moderate	Genetic Variation	[1567]
KIF14	OTXHT4JM	moderate	Altered Expression	[1568]
KIF4A	OT3UWL7D	moderate	Biomarker	[1569]
KLF15	OTGMQMVR	moderate	Biomarker	[1570]
LMOD1	OTZ2MEMG	moderate	Biomarker	[1571]
LYPD4	OTYNO8BS	moderate	Biomarker	[1572]
LYPD8	OT5B9NNM	moderate	Altered Expression	[1573]
MAD2L2	OT24ZO59	moderate	Biomarker	[1574]
MAP9	OTZD5099	moderate	Genetic Variation	[1575]
MARCHF1	OTI2EYO6	moderate	Biomarker	[1576]
MEP1A	OTY2Z48T	moderate	Biomarker	[1577]
METTL14	OT6TPQMH	moderate	Biomarker	[1578]
MIB1	OT5C404P	moderate	Biomarker	[1579]
MOAP1	OTVF3LUG	moderate	Altered Expression	[1580]
MPPED2	OT7XLMJ6	moderate	Biomarker	[1581]
MPZ	OTAR2YXH	moderate	Biomarker	[270]
MUC5B	OTPW6K5C	moderate	Genetic Variation	[1582]
NBN	OT73B5MD	moderate	Genetic Variation	[1372]
NDRG3	OTJTJCHD	moderate	Biomarker	[1583]
NEU1	OTH9BY8Y	moderate	Genetic Variation	[1582]
NFIL3	OTQH9HM3	moderate	Biomarker	[1584]
NMI	OTYVG3NM	moderate	Altered Expression	[176]
NPC1	OTRIPICX	moderate	Biomarker	[777]
NRIP1	OTIZOJQV	moderate	Genetic Variation	[1585]
NUCKS1	OTL4VJC5	moderate	Altered Expression	[1586]
OGDHL	OT1AZK6R	moderate	Biomarker	[1587]
OPN1MW	OTPJ7LX4	moderate	Biomarker	[1588]
PDCD4	OTZ6NXUX	moderate	Biomarker	[1554]
PDCD5	OT6T2DDL	moderate	Biomarker	[1589]
PGK1	OT6V1ICH	moderate	Biomarker	[1590]
PIAS3	OT3TWH9R	moderate	Altered Expression	[1591]
PIGF	OTJKE6VW	moderate	Biomarker	[1592]
PIK3R2	OTZSUQK5	moderate	Biomarker	[1202]
PIWIL4	OTDA9MY0	moderate	Biomarker	[1593]
PLXNA1	OTN0BING	moderate	Biomarker	[1514]
PMP22	OTXWYWCZ	moderate	Biomarker	[270]
PNPLA8	OT9V1T5W	moderate	Altered Expression	[1594]
POLD3	OTEQEFQ2	moderate	Genetic Variation	[364]
POLDIP2	OT8SZSJ6	moderate	Biomarker	[203]
POLH	OTN07WXU	moderate	Biomarker	[1066]
PPP1R12C	OT9Q86JO	moderate	Biomarker	[1202]
PPP1R13B	OTC88VQO	moderate	Biomarker	[1202]
PPP4C	OT4B0TNV	moderate	Altered Expression	[1595]
PROK1	OT8S7RUG	moderate	Altered Expression	[848]
PROK2	OT70IFEZ	moderate	Altered Expression	[1596]
PSMD14	OTJWHMZ5	moderate	Biomarker	[314]
PSMD4	OTH1VZTM	moderate	Biomarker	[1597]
PSPC1	OTYS6WQ8	moderate	Biomarker	[1598]
PTPN9	OTNAR1I2	moderate	Altered Expression	[1599]
PTS	OTTYWQXR	moderate	Altered Expression	[1600]
RAB11A	OTC4FW0J	moderate	Biomarker	[1601]
RAB3D	OTGKRR3C	moderate	Biomarker	[1602]
RAP1A	OT5RH6TI	moderate	Altered Expression	[1603]
RAP1GAP	OTC31ONQ	moderate	Altered Expression	[1604]
RASGRP1	OTX9WN2E	moderate	Genetic Variation	[1605]
RBBP6	OTTVG4HU	moderate	Biomarker	[1606]
RCC2	OTUJVTLS	moderate	Biomarker	[1607]
RCOR1	OTREADPC	moderate	Genetic Variation	[1608]
RHBDF1	OTCQ7UDS	moderate	Altered Expression	[1609]
RNF19A	OTKWCV80	moderate	Biomarker	[203]
RPIA	OT805SMH	moderate	Biomarker	[1610]
RPL10	OTBHOZGC	moderate	Biomarker	[1514]
RPRD1B	OTB41D5K	moderate	Genetic Variation	[1611]
RPS15A	OT0BUA12	moderate	Biomarker	[1612]
SAA2	OTYAVJWG	moderate	Altered Expression	[289]
SCGN	OTGD7SKH	moderate	Altered Expression	[1613]
SEPTIN2	OT3G33TM	moderate	Biomarker	[290]
SHC1	OT1J5IRN	moderate	Genetic Variation	[1108]
SIM2	OT0QWHK4	moderate	Altered Expression	[1614]
SIX4	OTG2HFH0	moderate	Biomarker	[1615]
SLAIN2	OTSM5QIO	moderate	Biomarker	[1616]
SMOC2	OTK1EQ49	moderate	Genetic Variation	[1617]
SMUG1	OT2YIOCQ	moderate	Biomarker	[233]
SNX9	OTLNQ0ZM	moderate	Altered Expression	[1618]
SORCS1	OTP8PAKU	moderate	Biomarker	[1619]
SOX13	OTCIF6KC	moderate	Biomarker	[203]
SPATA2	OTOA45GL	moderate	Biomarker	[950]
SRCIN1	OTQZNQQ5	moderate	Altered Expression	[1620]
STYX	OT8W6Y1J	moderate	Biomarker	[1621]
TEAD4	OTJS0T2B	moderate	Biomarker	[1622]
TESC	OTI8C76M	moderate	Altered Expression	[923]
TET2	OTKKT03T	moderate	Genetic Variation	[215]
TGFBRAP1	OT80QNR5	moderate	Altered Expression	[1623]
THSD7A	OT7249HH	moderate	Altered Expression	[1624]
TLR10	OTQ1KVJO	moderate	Genetic Variation	[999]
TMEM106B	OTUWA6NW	moderate	Altered Expression	[1625]
TMEM158	OT0KUBBI	moderate	Biomarker	[1626]
TMEM45A	OT54KJG6	moderate	Altered Expression	[1627]
TNFAIP8L1	OTVVKOTV	moderate	Biomarker	[1628]
TNNT1	OT8PBOAR	moderate	Altered Expression	[1629]
TOX	OTE8BL5Z	moderate	Biomarker	[1630]
TP53BP2	OTOWJ2Y4	moderate	Altered Expression	[1631]
TP53INP1	OT2363Z9	moderate	Altered Expression	[1593]
TP53INP2	OT0GTBXO	moderate	Biomarker	[273]
TRAF1	OTTLM5RU	moderate	Posttranslational Modification	[1632]
TRIM14	OTLQKUG0	moderate	Altered Expression	[1633]
TRIM31	OT7VW6RP	moderate	Biomarker	[1634]
TTF1	OT4K90WD	moderate	Genetic Variation	[1635]
A1CF	OTJBKFA1	Strong	Genetic Variation	[356]
AANAT	OTUBJ7SX	Strong	Biomarker	[1636]
AASDH	OTUIAJ48	Strong	Genetic Variation	[1637]
ABCB10	OT1C44F9	Strong	Genetic Variation	[1353]
ABCF1	OT6Q079J	Strong	Biomarker	[1638]
ABI1	OT5H4M62	Strong	Biomarker	[1639]
ABI2	OT8GIIS5	Strong	Biomarker	[1640]
ACAA1	OTVKRET0	Strong	Genetic Variation	[997]
ACACA	OT5CQPZY	Strong	Genetic Variation	[1641]
ACAD8	OT3JI5GB	Strong	Biomarker	[1642]
ACADM	OTA4P0FC	Strong	Altered Expression	[309]
ACCS	OTHIHI9D	Strong	Genetic Variation	[1142]
ACIN1	OTK81F92	Strong	Biomarker	[775]
ACKR4	OTZPWT2N	Strong	Altered Expression	[1643]
ACOX1	OTM0A0DY	Strong	Biomarker	[1644]
ACOXL	OTW680HT	Strong	Genetic Variation	[1645]
ACRBP	OT0MK3L1	Strong	Altered Expression	[1646]
ACSL4	OTI71MUJ	Strong	Altered Expression	[1647]
ACSL5	OT3L9XO3	Strong	Altered Expression	[1648]
ACSS1	OT6C1WQD	Strong	Altered Expression	[1649]
ACTB	OT1MCP2F	Strong	Biomarker	[1650]
ACTBL2	OTD6B81U	Strong	Biomarker	[1651]
ACTL8	OTUDD0QT	Strong	Altered Expression	[1652]
ACTN4	OTCNZAJ5	Strong	Biomarker	[1653]
ACTR1B	OTGBCKLO	Strong	Genetic Variation	[1287]
ACTRT1	OTHFKSIZ	Strong	Biomarker	[1640]
ACTRT3	OT2U08K8	Strong	Genetic Variation	[1287]
ACY1	OT9WU7X3	Strong	Biomarker	[1654]
ADAM19	OTH88TXU	Strong	Biomarker	[1655]
ADAMTS14	OTFJ1PDB	Strong	Biomarker	[1656]
ADAMTS15	OTYB6JS3	Strong	Biomarker	[1657]
ADAMTS16	OTTKUH99	Strong	Altered Expression	[1658]
ADAMTS18	OTRMFI04	Strong	Biomarker	[1659]
ADAMTS8	OT2KFY1S	Strong	Altered Expression	[1660]
ADAMTS9	OTV3Q0DS	Strong	Biomarker	[1661]
ADAMTSL3	OTMC2WFG	Strong	Genetic Variation	[1662]
ADAR	OTQNOHR8	Strong	Altered Expression	[1663]
ADARB1	OTGKSZEV	Strong	Biomarker	[1664]
ADCY3	OTGOQM6B	Strong	Biomarker	[588]
ADD1	OTTF68DC	Strong	Biomarker	[1665]
ADD2	OTRCPCD2	Strong	Biomarker	[1666]
ADGRA2	OTBT4W36	Strong	Biomarker	[278]
ADGRA3	OTPJEV0S	Strong	Altered Expression	[1667]
ADGRB1	OTJSEXRC	Strong	Biomarker	[1380]
ADGRE2	OTUYJVYG	Strong	Altered Expression	[1668]
ADGRE5	OTTSB84Q	Strong	Altered Expression	[1668]
ADGRF5	OTWU7AOO	Strong	Altered Expression	[557]
ADGRG1	OTQBB8NT	Strong	Biomarker	[1669]
ADIPOR2	OT2HDTL8	Strong	Genetic Variation	[1670]
ADNP	OTEGICWR	Strong	Biomarker	[1671]
AEBP1	OTBI1RZ6	Strong	Altered Expression	[1672]
AFAP1L1	OTWNTNDB	Strong	Biomarker	[1673]
AFAP1L2	OTJBI0VN	Strong	Altered Expression	[1674]
AGAP3	OT8C6PKL	Strong	Altered Expression	[1675]
AHI1	OT8K2YWY	Strong	Biomarker	[1676]
AIFM1	OTKPWB7Q	Strong	Biomarker	[1677]
AIMP1	OTTA5C3U	Strong	Biomarker	[1678]
AJUBA	OTNW7YPK	Strong	Altered Expression	[1679]
AK6	OT84OHHP	Strong	Biomarker	[1680]
AKAP10	OTPNFTOU	Strong	Altered Expression	[1681]
AKAP12	OTCVRDDX	Strong	Altered Expression	[80]
AKAP4	OTL4Z99V	Strong	Biomarker	[1682]
AKIRIN2	OTQ6WSKW	Strong	Biomarker	[1683]
ALDH1A3	OT1C9NKQ	Strong	Biomarker	[1684]
ALDOB	OT7FR69A	Strong	Biomarker	[1685]
ALPK1	OTBW6SGD	Strong	Biomarker	[1686]
ALPK2	OTWZZDQ9	Strong	Genetic Variation	[1687]
ALX4	OTNS9A29	Strong	Biomarker	[1688]
AMBP	OTLU8GU8	Strong	Biomarker	[345]
AMELX	OTIN26MM	Strong	Biomarker	[1689]
AMER1	OT8EFJPM	Strong	Genetic Variation	[1690]
AMFR	OTQRX7LC	Strong	Altered Expression	[1691]
AMOTL2	OTRCTKV9	Strong	Altered Expression	[1692]
AMT	OTQYEWZQ	Strong	Biomarker	[1693]
ANAPC10	OTM03SME	Strong	Altered Expression	[1694]
ANAPC11	OTK2SJXR	Strong	Altered Expression	[1695]
ANGPTL2	OTB6JG41	Strong	Biomarker	[1696]
ANKLE1	OTQ7WN9J	Strong	Genetic Variation	[1697]
ANKRD12	OTK16BL9	Strong	Altered Expression	[1698]
ANKRD36B	OT3MW415	Strong	Biomarker	[1699]
ANO9	OTQ2UM3M	Strong	Altered Expression	[1700]
ANOS1	OTZJT4KN	Strong	Biomarker	[1701]
ANP32A	OTRHPFO2	Strong	Altered Expression	[1702]
ANP32B	OT3SQMLU	Strong	Altered Expression	[1009]
ANTXR1	OT5W1GPC	Strong	Biomarker	[1703]
ANXA13	OTM33P73	Strong	Biomarker	[1704]
ANXA4	OTUCRYXL	Strong	Biomarker	[1705]
ANXA9	OTKNYMU2	Strong	Biomarker	[1706]
AP2A1	OTEFZB21	Strong	Biomarker	[990]
AP3B1	OTYTIH5Q	Strong	Biomarker	[1707]
APAF1	OTJWIVY0	Strong	Biomarker	[1708]
APBA1	OTUH9JPD	Strong	Posttranslational Modification	[390]
APBA2	OTXD8ID1	Strong	Posttranslational Modification	[390]
APIP	OT8ZABOU	Strong	Genetic Variation	[928]
APMAP	OT1P2GJA	Strong	Biomarker	[1709]
APOC1	OTA58CED	Strong	Biomarker	[1710]
APOD	OTT77XW8	Strong	Biomarker	[1711]
APOM	OTI3FQQC	Strong	Biomarker	[1712]
APPL1	OT8VR95S	Strong	Altered Expression	[1713]
APPL2	OT9S4C4K	Strong	Altered Expression	[1714]
AQP5	OT77GBY8	Strong	Biomarker	[1715]
AQP6	OTXS6UYY	Strong	Biomarker	[1716]
AQP8	OT99JKME	Strong	Altered Expression	[1717]
ARF6	OTVV7KJO	Strong	Genetic Variation	[1718]
ARFGAP1	OTM3KHIE	Strong	Biomarker	[1718]
ARHGAP24	OTCQCEZS	Strong	Biomarker	[1719]
ARHGAP30	OTESZLFG	Strong	Altered Expression	[1720]
ARHGDIA	OTEXWJDO	Strong	Biomarker	[181]
ARHGDIB	OT9PD6CS	Strong	Altered Expression	[1721]
ARHGEF12	OTM2D3LT	Strong	Biomarker	[1722]
ARHGEF25	OT7162TD	Strong	Altered Expression	[1723]
ARID1B	OTILK3Q7	Strong	Genetic Variation	[1203]
ARID3A	OTZZ4SFP	Strong	Altered Expression	[1724]
ARID4A	OT1XKBZ0	Strong	Biomarker	[1725]
ARID4B	OTYLPILE	Strong	Biomarker	[1726]
ARIH1	OTO3XDR2	Strong	Altered Expression	[1727]
ARL11	OTF6UDDB	Strong	Genetic Variation	[1728]
ARL4C	OTQ3QNNU	Strong	Altered Expression	[1729]
ARL5A	OTF7AQK9	Strong	Biomarker	[1730]
ARL6IP1	OT536XAV	Strong	Biomarker	[1640]
ARNT	OTMSIEZY	Strong	Altered Expression	[1731]
ARPC4	OT0ZE01B	Strong	Biomarker	[1732]
ART1	OT7FBG5W	Strong	Biomarker	[1733]
ARTN	OTWIWGL6	Strong	Biomarker	[326]
ASAH1	OT1DNGXL	Strong	Biomarker	[1734]
ASAP1	OT4DLRYY	Strong	Altered Expression	[1735]
ASB3	OTI3TK38	Strong	Genetic Variation	[1736]
ASB4	OTI4AFZL	Strong	Biomarker	[1737]
ASCC1	OTH4VAP9	Strong	Biomarker	[1738]
ASCL2	OT3D62WB	Strong	Biomarker	[1739]
ASF1A	OT4S44GP	Strong	Altered Expression	[1740]
ASL	OTI2NGQR	Strong	Biomarker	[1741]
ASPM	OTKXQMNA	Strong	Genetic Variation	[356]
ASPRV1	OT8WVIBW	Strong	Biomarker	[1742]
ATF1	OT251CI0	Strong	Genetic Variation	[215]
ATF2	OTNIZPEA	Strong	Altered Expression	[1743]
ATF6	OTAFHAVI	Strong	Altered Expression	[1744]
ATF7	OTM8T3OD	Strong	Biomarker	[1745]
ATG12	OTJRO09Y	Strong	Biomarker	[1746]
ATG16L1	OTEOYC5D	Strong	Genetic Variation	[1747]
ATG4B	OTQ4RNRM	Strong	Biomarker	[1748]
ATG5	OT4T5SMS	Strong	Biomarker	[1749]
ATN1	OTNZFLKY	Strong	Biomarker	[1750]
ATOH8	OT7SY3BN	Strong	Altered Expression	[1751]
ATP2B4	OTMWFDAC	Strong	Biomarker	[1752]
ATP5F1A	OT3FZDLX	Strong	Biomarker	[1753]
ATP5F1B	OTLFZUQK	Strong	Biomarker	[1752]
ATP8B1	OTALGS63	Strong	Biomarker	[1754]
ATRX	OT77RSQW	Strong	Biomarker	[1755]
ATXN7	OTL3YF1H	Strong	Altered Expression	[1756]
AXIN1	OTRGZGZ5	Strong	Genetic Variation	[1271]
AZIN1	OTX5W77I	Strong	Biomarker	[1213]
B3GALT4	OTLKSMQE	Strong	Biomarker	[1757]
B3GAT1	OTXFP98E	Strong	Biomarker	[414]
B3GNT6	OTAX8BNJ	Strong	Altered Expression	[1758]
B4GALNT3	OT6BFB22	Strong	Altered Expression	[1759]
B4GALT2	OTYIQT2F	Strong	Biomarker	[1760]
B4GALT3	OTHX77K8	Strong	Biomarker	[1761]
B4GALT5	OTHMZY12	Strong	Biomarker	[1762]
B4GALT6	OTBM8F2U	Strong	Biomarker	[1762]
B9D2	OT5SS4P8	Strong	Genetic Variation	[1157]
BAALC	OTUZSRVF	Strong	Genetic Variation	[1763]
BABAM1	OTCFPER6	Strong	Genetic Variation	[607]
BAD	OT63ERYM	Strong	Altered Expression	[1764]
BAG4	OTUPX3M2	Strong	Biomarker	[1765]
BAMBI	OTCEJ8W5	Strong	Genetic Variation	[1766]
BANF1	OTP7Z38L	Strong	Genetic Variation	[1767]
BANP	OT1JMTBD	Strong	Biomarker	[1768]
BARX2	OT0R3QD3	Strong	Altered Expression	[1769]
BATF	OT9VSD2D	Strong	Biomarker	[1770]
BATF2	OT4XBZC9	Strong	Biomarker	[1771]
BCAM	OTHZOPSD	Strong	Biomarker	[1772]
BCAR1	OTKT2C2N	Strong	Biomarker	[858]
BCL2L10	OTYXQJ3I	Strong	Altered Expression	[1773]
BCL3	OT1M5B95	Strong	Altered Expression	[1774]
BCL6B	OT1T5KM6	Strong	Biomarker	[1775]
BCL9	OTRBIPR4	Strong	Biomarker	[1776]
BCL9L	OTTWI90E	Strong	Genetic Variation	[1777]
BCR	OTCN76C1	Strong	Biomarker	[1778]
BEND5	OT6J6LY3	Strong	Posttranslational Modification	[1779]
BEST4	OT6S406I	Strong	Biomarker	[362]
BICC1	OTYRKIJ1	Strong	Genetic Variation	[471]
BICRA	OTDTPGW0	Strong	Biomarker	[1780]
BID	OTOSHSHU	Strong	Altered Expression	[1781]
BIK	OTTH1T3D	Strong	Altered Expression	[1782]
BIN1	OTK8O0X8	Strong	Biomarker	[1783]
BIRC6	OTCQJAB0	Strong	Biomarker	[1784]
BLM	OTEJOAJX	Strong	Altered Expression	[1785]
BMF	OT90NSLI	Strong	Altered Expression	[375]
BMP3	OTCTI0UW	Strong	Biomarker	[273]
BMP5	OTC0Y6E0	Strong	Genetic Variation	[215]
BMPR1A	OTQOA4ZH	Strong	Genetic Variation	[1786]
BMPR1B	OTGFN0OD	Strong	Biomarker	[1787]
BMS1	OTEGQ8ZO	Strong	Biomarker	[1788]
BNIP3	OT4SO7J4	Strong	Biomarker	[1789]
BOC	OTXBCY9W	Strong	Genetic Variation	[215]
BOK	OTDQPDIX	Strong	Biomarker	[19]
BOP1	OTMZMQDO	Strong	Biomarker	[1790]
BORCS5	OTAT6H8Q	Strong	Altered Expression	[1791]
BPIFA1	OTQFD2J5	Strong	Biomarker	[1792]
BPTF	OTD1RZAD	Strong	Altered Expression	[1793]
BRCA1	OT5BN6VH	Strong	Biomarker	[1794]
BRD8	OTIKS3PC	Strong	Biomarker	[1795]
BRF1	OTQC6DMG	Strong	Genetic Variation	[1796]
BRINP1	OTEUVSCP	Strong	Biomarker	[1797]
BRMS1	OTV5A6LL	Strong	Biomarker	[1798]
BTBD7	OTNUV6MQ	Strong	Biomarker	[1799]
BTBD9	OTWQ6GA3	Strong	Genetic Variation	[1800]
BTC	OTW4B2O0	Strong	Genetic Variation	[1801]
BTF3	OT5ZZFJL	Strong	Biomarker	[1802]
BTG4	OTT3TKPI	Strong	Posttranslational Modification	[1194]
BTN3A1	OTGZADIX	Strong	Biomarker	[1803]
BTRC	OT2EZDGR	Strong	Biomarker	[1804]
BUB1B	OT8KME51	Strong	Biomarker	[1805]
BZW1	OT4GUFIG	Strong	Biomarker	[1676]
C14orf28	OTMAF0NU	Strong	Biomarker	[1806]
C1GALT1	OT2ZSZ6P	Strong	Biomarker	[1807]
C1GALT1C1	OTRTZUF5	Strong	Altered Expression	[1808]
C1orf21	OTMD7O88	Strong	Genetic Variation	[43]
C1R	OTA0ZNIU	Strong	Biomarker	[1809]
CA8	OT9Y8GA8	Strong	Altered Expression	[1810]
CAB39	OT2CL9ST	Strong	Biomarker	[1811]
CABLES1	OTMN4XSX	Strong	Posttranslational Modification	[1812]
CABLES2	OTGD9A2A	Strong	Genetic Variation	[364]
CACUL1	OT6P1ZVP	Strong	Altered Expression	[1471]
CACYBP	OTJMZD2T	Strong	Biomarker	[1813]
CALCOCO1	OT1PAIN0	Strong	Altered Expression	[1814]
CALM2	OTNYA92F	Strong	Altered Expression	[1815]
CAMK2B	OTS9YK3E	Strong	Altered Expression	[670]
CAMKMT	OTLJBRUW	Strong	Altered Expression	[1815]
CAP1	OTYM8A2N	Strong	Biomarker	[1816]
CAPG	OTJ86KI6	Strong	Biomarker	[1817]
CAPN10	OTS9LJW4	Strong	Genetic Variation	[1818]
CAPS	OTC9GZ2M	Strong	Biomarker	[1223]
CARD10	OT2RPM4I	Strong	Biomarker	[1819]
CARF	OTWE0T6Q	Strong	Biomarker	[1820]
CASK	OT8EF7ZF	Strong	Biomarker	[1821]
CASP14	OTKY93H9	Strong	Genetic Variation	[1822]
CASZ1	OTWJ2OR8	Strong	Altered Expression	[1823]
CAVIN1	OTFO915U	Strong	Biomarker	[1824]
CAVIN3	OTOLBK79	Strong	Posttranslational Modification	[416]
CBLL2	OTB4AD3V	Strong	Biomarker	[374]
CBLN2	OT29SSBE	Strong	Genetic Variation	[1800]
CBX3	OTOP9RLD	Strong	Biomarker	[1825]
CBX4	OT4XVRRF	Strong	Biomarker	[1826]
CBY2	OTYUPDIB	Strong	Biomarker	[1827]
CCAR2	OTLUDG5T	Strong	Biomarker	[1797]
CCBE1	OTO4UIDB	Strong	Altered Expression	[1828]
CCDC43	OTK7OMHK	Strong	Altered Expression	[1829]
CCDC66	OTE8VSSO	Strong	Altered Expression	[1830]
CCDC88A	OT3SSYYC	Strong	Biomarker	[1831]
CCL1	OT23NON8	Strong	Biomarker	[1832]
CCL15	OTOGZ85M	Strong	Biomarker	[1476]
CCL19	OTQ2UJMH	Strong	Biomarker	[1833]
CCL24	OT9LGHV0	Strong	Biomarker	[1834]
CCL4	OT6B8P25	Strong	Biomarker	[27]
CCL4L2	OTDBSXOU	Strong	Biomarker	[1835]
CCNA1	OTX4HD45	Strong	Posttranslational Modification	[1836]
CCNC	OTMVK4K4	Strong	Biomarker	[435]
CCNG2	OTII38K2	Strong	Biomarker	[1837]
CCS	OTXHT3QO	Strong	Biomarker	[1838]
CD109	OTDADBM4	Strong	Biomarker	[1484]
CD226	OT4UG0KB	Strong	Biomarker	[1481]
CD68	OTOYEY3J	Strong	Altered Expression	[415]
CD82	OTH8MC64	Strong	Altered Expression	[1839]
CD93	OT6HZT6H	Strong	Genetic Variation	[1840]
CDC14A	OTL10OY6	Strong	Genetic Variation	[1352]
CDC27	OTDT45XJ	Strong	Biomarker	[1841]
CDC42SE2	OT8SG9I1	Strong	Genetic Variation	[1842]
CDC5L	OTTPFUU5	Strong	Altered Expression	[1843]
CDCA2	OTX8UF9J	Strong	Altered Expression	[1844]
CDCP1	OTD7RRWK	Strong	Biomarker	[1845]
CDH10	OTK3D5WP	Strong	Genetic Variation	[1846]
CDH12	OTF2HCGA	Strong	Biomarker	[1847]
CDH13	OTD2CYM5	Strong	Posttranslational Modification	[1848]
CDH24	OTNS0BWU	Strong	Genetic Variation	[1849]
CDH4	OT8LH3HN	Strong	Posttranslational Modification	[1850]
CDHR2	OTTHEUPO	Strong	Altered Expression	[1851]
CDHR5	OTTBWQMN	Strong	Biomarker	[1851]
CDK10	OTKP7TTR	Strong	Biomarker	[1852]
CDK14	OT385ZH1	Strong	Altered Expression	[1853]
CDK2AP1	OTNFOHDJ	Strong	Altered Expression	[1694]
CDKL4	OT0N2OWL	Strong	Genetic Variation	[730]
CDKN2B	OTAG24N1	Strong	Biomarker	[1854]
CDKN2D	OT2TTZPZ	Strong	Altered Expression	[1855]
CDO1	OTLG1P77	Strong	Biomarker	[1856]
CDS1	OT2F591M	Strong	Genetic Variation	[445]
CDX1	OTOHTMJE	Strong	Biomarker	[1857]
CEACAM8	OTLL9WWO	Strong	Biomarker	[1858]
CEBPD	OTNBIPMY	Strong	Biomarker	[1859]
CELF3	OTTP45WK	Strong	Biomarker	[1860]
CELSR3	OT8P6QNJ	Strong	Biomarker	[1031]
CEMIP	OTK80FYN	Strong	Biomarker	[1861]
CENPA	OT0NEJ4X	Strong	Altered Expression	[1862]
CENPF	OT7AG0SW	Strong	Biomarker	[280]
CENPH	OTPOO9LK	Strong	Altered Expression	[1863]
CENPI	OTWRIMZ3	Strong	Altered Expression	[1864]
CEP72	OTVYNPNL	Strong	Biomarker	[1865]
CEP78	OTTAI5S2	Strong	Altered Expression	[1866]
CERS4	OTV5ENAX	Strong	Biomarker	[1867]
CERS6	OTOP4GV1	Strong	Biomarker	[1867]
CFAP44	OT1273MD	Strong	Genetic Variation	[1800]
CFL1	OTT6D5MH	Strong	Biomarker	[1868]
CHD1	OT9R9G0H	Strong	Genetic Variation	[215]
CHD1L	OT7CZK7C	Strong	Altered Expression	[1869]
CHD4	OTBDEHDP	Strong	Biomarker	[1870]
CHD8	OTS7A6AF	Strong	Genetic Variation	[1871]
CHD9	OTWNFDKJ	Strong	Biomarker	[1872]
CHFR	OTRAD2TT	Strong	Posttranslational Modification	[1873]
CHGA	OTXYX5JH	Strong	Biomarker	[1874]
CHL1	OT6E6E8P	Strong	Biomarker	[1875]
CHPT1	OT4FJ0K3	Strong	Biomarker	[1876]
CHRDL2	OTJU2I5H	Strong	Genetic Variation	[215]
CHSY1	OTB1XSSF	Strong	Altered Expression	[1877]
CHSY3	OT8ERGMH	Strong	Genetic Variation	[1842]
CHTOP	OTMMNZ65	Strong	Biomarker	[1878]
CIB1	OT4BVCRU	Strong	Altered Expression	[1879]
CIB2	OT9ZJX1I	Strong	Altered Expression	[1880]
CIC	OTFXCHNZ	Strong	Biomarker	[1881]
CIP2A	OTVS2GXA	Strong	Altered Expression	[1882]
CISD3	OT0MM1MW	Strong	Biomarker	[1239]
CISH	OT8T5NYL	Strong	Biomarker	[1448]
CITED1	OTUJQ3VL	Strong	Altered Expression	[1883]
CITED4	OTR6NHI2	Strong	Biomarker	[1884]
CIZ1	OT3UKHPI	Strong	Biomarker	[1885]
CKAP2	OTCLTC0J	Strong	Biomarker	[1886]
CKAP4	OTDUC9ME	Strong	Altered Expression	[882]
CKLF	OTHLPHA0	Strong	Biomarker	[1887]
CKMT1A	OTCINHH5	Strong	Altered Expression	[1888]
CKS1B	OTNUPLUJ	Strong	Altered Expression	[1889]
CKS2	OTPTMHIV	Strong	Biomarker	[1790]
CLCA2	OTF191LZ	Strong	Biomarker	[1890]
CLDN1	OT27KV99	Strong	Genetic Variation	[1354]
CLDN11	OTNN6UTL	Strong	Biomarker	[296]
CLDN23	OTN5RV40	Strong	Altered Expression	[1891]
CLDN7	OTNE0XHQ	Strong	Altered Expression	[1892]
CLDN8	OT7IIWXG	Strong	Altered Expression	[1893]
CLEC3A	OTTOAEGT	Strong	Genetic Variation	[989]
CLEC3B	OTFD29NF	Strong	Altered Expression	[1650]
CLOCK	OTNEOJY7	Strong	Biomarker	[1894]
CMTM4	OTA3Z072	Strong	Biomarker	[1895]
CNBP	OTTGM9NK	Strong	Biomarker	[1896]
CNN3	OTJTAXAP	Strong	Biomarker	[1897]
CNOT3	OT4D5Z9L	Strong	Biomarker	[1898]
CNPY2	OTGY8ESX	Strong	Biomarker	[1899]
CNRIP1	OTXPWJ56	Strong	Biomarker	[1900]
COG8	OTDEA7YO	Strong	Altered Expression	[1901]
COL10A1	OTC4G2YC	Strong	Altered Expression	[1902]
COL11A1	OTB0DRMS	Strong	Altered Expression	[1249]
COL11A2	OT3BQUBH	Strong	Altered Expression	[800]
COL27A1	OTQ5VDRH	Strong	Genetic Variation	[1582]
COL3A1	OTT1EMLM	Strong	Biomarker	[1903]
COL4A2	OTJK1LKN	Strong	Genetic Variation	[215]
COLCA1	OT8BP6UD	Strong	Genetic Variation	[364]
COMMD10	OT1ANQLQ	Strong	Altered Expression	[1904]
COPE	OTBKHBT7	Strong	Biomarker	[1905]
COX1	OTG3O9BN	Strong	Altered Expression	[1906]
COX5A	OTP0961M	Strong	Altered Expression	[1907]
COX8A	OTU0NR39	Strong	Altered Expression	[1907]
CPEB2	OTKES4YR	Strong	Biomarker	[1908]
CPEB4	OTW1SCZW	Strong	Biomarker	[1909]
CPNE3	OTCR3WG2	Strong	Altered Expression	[1910]
CPOX	OTIAY121	Strong	Altered Expression	[1907]
CPSF3	OTS3KSNG	Strong	Biomarker	[184]
CPT1A	OTI862QH	Strong	Biomarker	[1911]
CPT2	OTIN6G20	Strong	Altered Expression	[309]
CRACD	OTII2U6L	Strong	Biomarker	[1912]
CREB5	OTJDUJPI	Strong	Biomarker	[1913]
CRIP1	OT0EICG3	Strong	Biomarker	[1250]
CRISP2	OT8HLTV5	Strong	Altered Expression	[1914]
CRISPLD2	OTVSFHTL	Strong	Biomarker	[1915]
CRLS1	OT7XNL0K	Strong	Biomarker	[884]
CRTAP	OT53H5U6	Strong	Genetic Variation	[1916]
CRTC3	OTVIGVUW	Strong	Genetic Variation	[1287]
CRX	OTH435SV	Strong	Biomarker	[883]
CSMD2	OT541Z3W	Strong	Altered Expression	[1917]
CSMD3	OTAT75SW	Strong	Biomarker	[1917]
CSN2	OT22C0PD	Strong	Biomarker	[1526]
CST1	OTE4I83Q	Strong	Biomarker	[1918]
CST4	OTXXM8EH	Strong	Biomarker	[1919]
CSTB	OT3U0JF8	Strong	Altered Expression	[1920]
CT47A11	OTQHGP0S	Strong	Altered Expression	[1921]
CT55	OTQC0H27	Strong	Biomarker	[1922]
CTBP1	OTVYH2DH	Strong	Biomarker	[1923]
CTCF	OT8ZB70U	Strong	Biomarker	[1924]
CTNNA1	OTFC725Z	Strong	Biomarker	[1925]
CTNNA3	OT9Z0P1E	Strong	Genetic Variation	[1926]
CTNND1	OTUMPSHR	Strong	Biomarker	[1927]
CTNND2	OTYKE30Y	Strong	Altered Expression	[1928]
CTSZ	OTSCX2LL	Strong	Biomarker	[1929]
CTTN	OTJRG4ES	Strong	Biomarker	[1930]
CUEDC2	OTWMOLAJ	Strong	Biomarker	[1931]
CUL4B	OT2QX4DO	Strong	Biomarker	[1932]
CUX1	OTU1LCNJ	Strong	Genetic Variation	[1916]
CXCL14	OTM189TA	Strong	Altered Expression	[1933]
CXXC1	OTO10D1N	Strong	Altered Expression	[1934]
CYB5R1	OTMDHMLA	Strong	Biomarker	[1935]
CYRIB	OTLRN4L1	Strong	Altered Expression	[1936]
CYTIP	OTRJ3ZC5	Strong	Genetic Variation	[1916]
DAB1	OTPL9MA3	Strong	Biomarker	[1937]
DAB2	OTRMQTMZ	Strong	Genetic Variation	[1938]
DAB2IP	OTF456VC	Strong	Biomarker	[1939]
DACH1	OTMKNAGG	Strong	Biomarker	[1940]
DACT1	OT19Z704	Strong	Biomarker	[215]
DACT2	OTNLCC0K	Strong	Altered Expression	[1941]
DACT3	OTSNQ55G	Strong	Biomarker	[1942]
DAND5	OTWNWQDJ	Strong	Altered Expression	[1943]
DAP	OT5YLL7E	Strong	Biomarker	[1944]
DAPK2	OTWODUQG	Strong	Posttranslational Modification	[1051]
DAXX	OTX6O7PL	Strong	Altered Expression	[1945]
DCBLD1	OTA702JK	Strong	Genetic Variation	[1946]
DCHS2	OTGZJ6KS	Strong	Genetic Variation	[1849]
DCLRE1B	OT2LFW7A	Strong	Altered Expression	[1947]
DCTN4	OTM7C943	Strong	Biomarker	[680]
DCUN1D1	OT8UJLZU	Strong	Altered Expression	[1948]
DDHD1	OTWTHOWK	Strong	Altered Expression	[1949]
DDIT3	OTI8YKKE	Strong	Altered Expression	[1950]
DDX1	OT3U8FD0	Strong	Genetic Variation	[1951]
DDX11	OT1WR3MD	Strong	Biomarker	[1952]
DDX17	OTXRMMBP	Strong	Altered Expression	[1953]
DDX3X	OTDO4TRX	Strong	Altered Expression	[1954]
DDX46	OTB2X9TO	Strong	Altered Expression	[1955]
DDX53	OTHK3EGZ	Strong	Biomarker	[411]
DEAF1	OTCLX3ZW	Strong	Altered Expression	[1956]
DEFA6	OTDJADMQ	Strong	Biomarker	[1957]
DEFB1	OT5SV0E4	Strong	Biomarker	[1958]
DEGS1	OT4WXPKW	Strong	Altered Expression	[1959]
DEGS2	OTXC27FL	Strong	Biomarker	[1959]
DENND5B	OTNDJJUR	Strong	Genetic Variation	[294]
DENR	OTXP9HOY	Strong	Posttranslational Modification	[1051]
DEPP1	OTB36PHJ	Strong	Genetic Variation	[512]
DES	OTI09KBW	Strong	Biomarker	[1960]
DGKB	OTTT9SZJ	Strong	Posttranslational Modification	[1961]
DGKE	OTWS86AS	Strong	Posttranslational Modification	[1961]
DGKG	OTBL32T3	Strong	Altered Expression	[1961]
DGUOK	OT78HUZB	Strong	Posttranslational Modification	[1961]
DHDDS	OTVLYBUS	Strong	Biomarker	[1876]
DHRS11	OTU3J0ZL	Strong	Altered Expression	[622]
DHRS2	OTFHWIY8	Strong	Altered Expression	[1962]
DHX32	OTDYB66V	Strong	Biomarker	[1963]
DHX58	OT19BYB1	Strong	Biomarker	[801]
DHX9	OT5AAOQI	Strong	Biomarker	[1964]
DIO2	OTGPNSLH	Strong	Altered Expression	[1965]
DIP2B	OTP6KH82	Strong	Genetic Variation	[525]
DIS3	OT7UPHJS	Strong	Altered Expression	[1966]
DIS3L2	OTWABM04	Strong	Biomarker	[1967]
DKK4	OTWCCVF6	Strong	Genetic Variation	[1968]
DLD	OT378CU9	Strong	Biomarker	[1969]
DLEC1	OTMKKBUW	Strong	Biomarker	[1970]
DMKN	OTRIGZMK	Strong	Biomarker	[1971]
DMTN	OTDTKPBW	Strong	Altered Expression	[1972]
DNAJB6	OTMHIIAN	Strong	Altered Expression	[1973]
DNAJB8	OT2CDBH6	Strong	Biomarker	[1881]
DOCK3	OTF3YS2W	Strong	Genetic Variation	[1800]
DOK1	OTGVRLW6	Strong	Biomarker	[1974]
DOK3	OT842U3C	Strong	Genetic Variation	[1975]
DPH1	OT0QU3JY	Strong	Altered Expression	[1976]
DPPA2	OT8Y55RY	Strong	Altered Expression	[1977]
DPPA4	OTAEOACS	Strong	Altered Expression	[1978]
DPYSL5	OT6F9T6F	Strong	Biomarker	[1675]
DRG1	OTIFYMI3	Strong	Genetic Variation	[1800]
DROSHA	OTCE68KZ	Strong	Altered Expression	[1979]
DSC2	OTODVH8K	Strong	Altered Expression	[1269]
DSCC1	OTPUVLZT	Strong	Altered Expression	[1980]
DUSP22	OTEZ3U85	Strong	Altered Expression	[1981]
DUSP4	OT6WAO12	Strong	Altered Expression	[1982]
DVL1	OTD67RF1	Strong	Altered Expression	[1983]
DYNC1H1	OTD1KRKO	Strong	Biomarker	[1984]
DYNLL1	OTR69LHT	Strong	Biomarker	[1970]
DYNLRB1	OTWVKOFB	Strong	Biomarker	[1985]
E2F5	OT1XWING	Strong	Biomarker	[1986]
E2F8	OTQKZGFP	Strong	Biomarker	[1987]
EBF1	OTZ61YYH	Strong	Altered Expression	[1049]
ECRG4	OTHZYUXX	Strong	Biomarker	[1988]
ECT2L	OTOSDMGV	Strong	Genetic Variation	[989]
EDN3	OTN7Q9BE	Strong	Altered Expression	[1989]
EEF1A1	OT00THXS	Strong	Biomarker	[1990]
EEF1G	OTW7DH2F	Strong	Biomarker	[1991]
EFCAB2	OTXEFI4O	Strong	Genetic Variation	[294]
EFEMP1	OTZVUOOB	Strong	Biomarker	[1992]
EFHD1	OTL5INE4	Strong	Biomarker	[1993]
EFNB2	OT0DCUOM	Strong	Altered Expression	[1994]
EGFL8	OTECTJ7K	Strong	Biomarker	[1995]
EI24	OTD4NOYS	Strong	Altered Expression	[1996]
EIF1	OTB4GZ0V	Strong	Biomarker	[1997]
EIF2S1	OTM0GDTP	Strong	Biomarker	[1998]
EIF2S2	OTXF0B09	Strong	Biomarker	[1998]
EIF2S3	OTARRES9	Strong	Biomarker	[1998]
EIF3A	OTFABY9G	Strong	Biomarker	[1997]
EIF3D	OTDOMP80	Strong	Genetic Variation	[1999]
EIF3E	OTI0WG98	Strong	Biomarker	[889]
EIF3H	OT61RBF5	Strong	Biomarker	[2000]
EIF4A1	OTMTBX6N	Strong	Biomarker	[2001]
EIF4A2	OT08H03R	Strong	Biomarker	[2002]
EIF4ENIF1	OTZWDB2X	Strong	Genetic Variation	[1800]
EIF4G1	OT2CF1E6	Strong	Biomarker	[746]
EIF5	OT79PQUN	Strong	Biomarker	[1997]
EIF5AL1	OTLA4ONW	Strong	Biomarker	[1860]
EIF6	OTEXMUED	Strong	Biomarker	[2003]
ELAVL2	OT6EJ8MQ	Strong	Biomarker	[209]
ELMO3	OTQHO9VM	Strong	Biomarker	[2004]
ELOVL5	OT375W1Z	Strong	Genetic Variation	[2005]
EMSY	OTBQ3KQE	Strong	Altered Expression	[1811]
EMX2	OT0V8OYK	Strong	Biomarker	[2006]
ENKUR	OTXXBBQT	Strong	Altered Expression	[2007]
ENO1	OTB1KWJS	Strong	Altered Expression	[2008]
ENOSF1	OT65D3ZK	Strong	Genetic Variation	[2009]
ENTPD5	OTFH05B9	Strong	Altered Expression	[2010]
EOMES	OTB9VQFA	Strong	Altered Expression	[375]
EPDR1	OT5JW5RB	Strong	Altered Expression	[2011]
EPG5	OT3P5HQD	Strong	Genetic Variation	[2012]
ERCC3	OTVAW3P1	Strong	Biomarker	[2013]
ERCC4	OTFIOPG1	Strong	Genetic Variation	[783]
ERCC6	OT2QZKSF	Strong	Altered Expression	[2014]
ERCC6L	OTE9V7D9	Strong	Altered Expression	[2015]
ERN2	OTUS6GKR	Strong	Altered Expression	[2016]
ERO1A	OTVKOQWM	Strong	Biomarker	[2017]
ERP29	OTNKANMH	Strong	Biomarker	[2018]
ESCO2	OTJEMAQU	Strong	Altered Expression	[2019]
ESM1	OT331Y8V	Strong	Biomarker	[2020]
ESRP2	OTVTKJ4I	Strong	Biomarker	[2021]
ETHE1	OTP9A2BQ	Strong	Biomarker	[2022]
ETV5	OTE2OBM4	Strong	Biomarker	[2023]
ETV6	OTCZMG61	Strong	Genetic Variation	[2024]
EVL	OTZ8ZDNY	Strong	Altered Expression	[2025]
EWSR1	OT7SRHV3	Strong	Altered Expression	[670]
EXOSC4	OTG4TICP	Strong	Altered Expression	[2026]
EXOSC5	OTADUQ7H	Strong	Altered Expression	[2027]
EYA1	OTHU807A	Strong	Biomarker	[2028]
EYA4	OTINGR3Z	Strong	Biomarker	[2029]
FABP6	OTIRQWLW	Strong	Altered Expression	[2030]
FAM171B	OT4DJHCM	Strong	Altered Expression	[2031]
FAM193A	OTT0W53G	Strong	Genetic Variation	[1800]
FAM83H	OTN0SF11	Strong	Biomarker	[2032]
FAN1	OT1LM1HZ	Strong	Genetic Variation	[2033]
FANCC	OTTIDM3P	Strong	Genetic Variation	[380]
FANCE	OTKRPBW1	Strong	Genetic Variation	[380]
FANCM	OTNJG99Z	Strong	Genetic Variation	[2033]
FARP2	OTNRQIMK	Strong	Biomarker	[2034]
FASTK	OTTHFZMP	Strong	Biomarker	[2035]
FBLIM1	OTFHXMON	Strong	Biomarker	[2036]
FBLN2	OTEHR7N7	Strong	Altered Expression	[2037]
FBLN5	OTLVNZ8U	Strong	Biomarker	[2038]
FBN2	OT3KYJQL	Strong	Biomarker	[2039]
FBP1	OTQBANEP	Strong	Biomarker	[2040]
FBXL3	OTDQ1QKV	Strong	Biomarker	[2041]
FBXO32	OTUE978R	Strong	Biomarker	[2042]
FBXO45	OTD4D2OP	Strong	Biomarker	[2043]
FERMT1	OT626PBA	Strong	Biomarker	[2044]
FERMT2	OTZNPWWX	Strong	Biomarker	[2045]
FEZF2	OTU4TXIW	Strong	Altered Expression	[1544]
FGA	OTMIHY80	Strong	Biomarker	[2046]
FGB	OT6RKLI9	Strong	Biomarker	[2047]
FGF9	OT2SKDGM	Strong	Genetic Variation	[2048]
FGL1	OTT0QHQ1	Strong	Biomarker	[1707]
FHL2	OT0OAYWT	Strong	Genetic Variation	[2049]
FHL3	OTMPRLZ5	Strong	Biomarker	[215]
FIBP	OTI7131S	Strong	Posttranslational Modification	[2050]
FJX1	OT8SVTSS	Strong	Altered Expression	[2051]
FKBP3	OT7ETKPE	Strong	Altered Expression	[2052]
FLII	OT7G9JG6	Strong	Biomarker	[2053]
FLOT1	OT0JPPJZ	Strong	Biomarker	[2054]
FLT3LG	OTU0YGC4	Strong	Biomarker	[2055]
FLYWCH1	OTWZVRX2	Strong	Biomarker	[2056]
FMN1	OT9CID5R	Strong	Genetic Variation	[215]
FMN2	OTUY7BSV	Strong	Biomarker	[2057]
FMNL2	OT9OVWCV	Strong	Biomarker	[2058]
FNDC5	OT5CSK9X	Strong	Altered Expression	[359]
FOCAD	OT83QOSI	Strong	Genetic Variation	[2059]
FOSB	OTW6C05J	Strong	Biomarker	[1675]
FOXA1	OTEBY0TD	Strong	Biomarker	[2060]
FOXD1	OT80PRHS	Strong	Altered Expression	[811]
FOXD3	OTXYV6GO	Strong	Altered Expression	[2061]
FOXD4	OTTY0FF2	Strong	Biomarker	[2062]
FOXE1	OT5IR5IT	Strong	Altered Expression	[2063]
FOXF2	OTV20NGX	Strong	Biomarker	[2064]
FOXH1	OTEXJ9SL	Strong	Biomarker	[2065]
FOXJ1	OT7LLBZ7	Strong	Biomarker	[2066]
FOXK1	OTLZGS7J	Strong	Biomarker	[1829]
FOXL1	OT89XFPN	Strong	Genetic Variation	[525]
FOXL2	OTFRQUYL	Strong	Genetic Variation	[760]
FOXO3	OTHXQG4P	Strong	Biomarker	[1038]
FOXO4	OT90X9LN	Strong	Biomarker	[2067]
FOXP2	OTVX6A59	Strong	Altered Expression	[2068]
FRY	OT74IAG2	Strong	Genetic Variation	[607]
FSD1	OT8P6PT3	Strong	Biomarker	[2069]
FSD1L	OTBQ48RF	Strong	Biomarker	[2069]
FSIP1	OTYLL6GM	Strong	Altered Expression	[2070]
FSTL1	OT6KEZUD	Strong	Biomarker	[1187]
FTL	OTYQA8A6	Strong	Altered Expression	[2071]
FUBP1	OT77SC9N	Strong	Altered Expression	[2072]
FUCA1	OTW71IK4	Strong	Altered Expression	[2073]
FUT1	OTODG57A	Strong	Biomarker	[2074]
FUT2	OTLXM6WI	Strong	Genetic Variation	[2075]
FUT5	OTOPGL9M	Strong	Biomarker	[2076]
FUT8	OTJJCVG1	Strong	Biomarker	[2077]
FUT9	OTLIJBQY	Strong	Biomarker	[2078]
FXR1	OTEMQ1SR	Strong	Biomarker	[2079]
FXYD3	OT9PPRHE	Strong	Biomarker	[2080]
FZD3	OTIWDN78	Strong	Genetic Variation	[460]
FZD4	OTGLZIE0	Strong	Biomarker	[2081]
FZD6	OTBCPII8	Strong	Altered Expression	[781]
FZD8	OTZ9IRFL	Strong	Biomarker	[2082]
GAB2	OTBFN705	Strong	Altered Expression	[2083]
GAB3	OTKX1KEC	Strong	Altered Expression	[2084]
GABBR1	OTU5A52J	Strong	Biomarker	[2085]
GADD45A	OTDRV63V	Strong	Biomarker	[2086]
GALNT1	OTO3RO36	Strong	Altered Expression	[2087]
GALNT11	OTANT9E6	Strong	Genetic Variation	[2088]
GALNT3	OT7M67WT	Strong	Biomarker	[2089]
GALNT4	OT6WKC13	Strong	Altered Expression	[2090]
GALNT5	OTCV61V1	Strong	Biomarker	[2091]
GALNT6	OTOQQVH1	Strong	Altered Expression	[2092]
GALNT7	OTUJSCAO	Strong	Biomarker	[941]
GAS1	OTKJXG52	Strong	Biomarker	[2093]
GAS2	OT50JKXQ	Strong	Altered Expression	[2094]
GAS7	OT0M5TNY	Strong	Altered Expression	[2095]
GAS8	OT8KT2AK	Strong	Biomarker	[2096]
GATA6	OTO2BC0F	Strong	Altered Expression	[2097]
GCA	OTAJ7ZHG	Strong	Genetic Variation	[2098]
GCDH	OTVQMZZN	Strong	Genetic Variation	[2099]
GCNT2	OTRUIMC4	Strong	Genetic Variation	[2100]
GCNT3	OTQ9ALTR	Strong	Biomarker	[2101]
GDPD5	OTUM65JL	Strong	Altered Expression	[2102]
GEN1	OT1XFQXF	Strong	Biomarker	[2103]
GID8	OT0HJ277	Strong	Altered Expression	[2104]
GINS3	OT8NVXTD	Strong	Posttranslational Modification	[2105]
GIPC1	OTXLVCPJ	Strong	Posttranslational Modification	[2106]
GIT1	OTHO92S5	Strong	Altered Expression	[455]
GLI3	OTKDOE94	Strong	Altered Expression	[2107]
GLRX3	OTUPAU1N	Strong	Biomarker	[2108]
GLS2	OT08MSHL	Strong	Genetic Variation	[2109]
GLTP	OTM78ZFI	Strong	Biomarker	[616]
GLUD1	OTXKOCUH	Strong	Biomarker	[2110]
GMFG	OTMPNSE7	Strong	Altered Expression	[2111]
GNA13	OTVDL515	Strong	Altered Expression	[2112]
GNAT1	OTK2SNJA	Strong	Biomarker	[2113]
GNB4	OTC1GPHA	Strong	Genetic Variation	[2114]
GNG12	OTOGF42G	Strong	Genetic Variation	[1800]
GOLM1	OTOZSV6O	Strong	Altered Expression	[2115]
GOLPH3	OTDLGYM3	Strong	Biomarker	[2116]
GOPC	OTRBGH71	Strong	Biomarker	[2036]
GORASP1	OTQS91S7	Strong	Biomarker	[755]
GOSR1	OTX8TMVU	Strong	Altered Expression	[2117]
GOT2	OT6XBWN0	Strong	Genetic Variation	[539]
GP2	OTB6TMGY	Strong	Biomarker	[2118]
GPAA1	OTWVRR35	Strong	Altered Expression	[2119]
GPATCH1	OTQRDBY6	Strong	Genetic Variation	[2120]
GPC1	OTQKRSSV	Strong	Altered Expression	[2121]
GPC4	OTUJ14DW	Strong	Biomarker	[2122]
GPC6	OTNJBESF	Strong	Biomarker	[2123]
GPR143	OTWUA2AV	Strong	Genetic Variation	[2124]
GPR151	OT7EACU6	Strong	Genetic Variation	[588]
GPR4	OTIBF32I	Strong	Altered Expression	[2125]
GPR68	OT1NXSMN	Strong	Biomarker	[2126]
GPRC5C	OT45AJT3	Strong	Genetic Variation	[587]
GPT2	OTS5VF7N	Strong	Biomarker	[2127]
GPX3	OT6PK94R	Strong	Posttranslational Modification	[2128]
GPX4	OTRAFFX2	Strong	Biomarker	[2129]
GRB14	OTFET2YM	Strong	Altered Expression	[2130]
GRK6	OT4LZTP9	Strong	Altered Expression	[2131]
GRP	OT8JDFNI	Strong	Biomarker	[78]
GSDMC	OTVM43E3	Strong	Biomarker	[2132]
GSDME	OT1ZWY32	Strong	Biomarker	[2133]
GSE1	OT3J7CJB	Strong	Genetic Variation	[2134]
GSPT1	OT18H1B0	Strong	Biomarker	[2135]
GSTM2	OTG4WT05	Strong	Genetic Variation	[2136]
GSTM3	OTLA2WJT	Strong	Biomarker	[1479]
GTF2B	OTAH5NSO	Strong	Biomarker	[715]
GTF2H1	OTCRXC6B	Strong	Biomarker	[680]
GTF2H5	OTRL219S	Strong	Biomarker	[2137]
GTPBP4	OT6ZHAWC	Strong	Biomarker	[2138]
GUCA2B	OTZERX04	Strong	Biomarker	[2139]
GUCY1A2	OTR6DVAA	Strong	Biomarker	[1484]
H2AJ	OTVA4XTW	Strong	Altered Expression	[2140]
H2AX	OT18UX57	Strong	Altered Expression	[1019]
H2AZ1	OT3KJJNQ	Strong	Altered Expression	[2141]
H3C1	OTGBGOZW	Strong	Genetic Variation	[760]
HADHB	OT4Y1I62	Strong	Altered Expression	[2142]
HAPLN1	OTXWR9TJ	Strong	Biomarker	[1484]
HAS2	OTTD3PAL	Strong	Biomarker	[2143]
HAVCR1	OT184CRZ	Strong	Biomarker	[2144]
HAVCR2	OTOL603T	Strong	Altered Expression	[2145]
HBP1	OTDPGGDV	Strong	Biomarker	[2146]
HEATR6	OTD3MYS0	Strong	Biomarker	[2147]
HELLS	OTVVV668	Strong	Biomarker	[1375]
HEPACAM	OT1MJ51D	Strong	Biomarker	[2148]
HERC2	OTNQYKOB	Strong	Genetic Variation	[1800]
HES1	OT8P19W2	Strong	Altered Expression	[2149]
HES6	OTWO5SCF	Strong	Altered Expression	[2150]
HEY1	OTJQL0I3	Strong	Biomarker	[2151]
HEYL	OTN7BH79	Strong	Altered Expression	[2152]
HFE	OTDD93KB	Strong	Genetic Variation	[2153]
HHLA2	OTYBTVQS	Strong	Biomarker	[2154]
HIBCH	OTU2VHWR	Strong	Biomarker	[2155]
HILPDA	OTEID3ZM	Strong	Biomarker	[2156]
HINT2	OTW9GS0U	Strong	Biomarker	[2157]
HIPK1	OTSEA8RS	Strong	Biomarker	[2158]
HIPK3	OT4WYQM2	Strong	Biomarker	[1333]
HK3	OTZKONGB	Strong	Biomarker	[1165]
HLA-C	OTV38BUJ	Strong	Genetic Variation	[684]
HLA-DOA	OTZE5Q7R	Strong	Genetic Variation	[2159]
HLA-DRB4	OTNXIHQU	Strong	Genetic Variation	[2160]
HLA-F	OT76CM19	Strong	Altered Expression	[2161]
HM13	OTGEO1LP	Strong	Biomarker	[1319]
HMMR	OT4M0JTZ	Strong	Biomarker	[2162]
HNF1B	OTSYIC3T	Strong	Altered Expression	[2163]
HNRNPC	OT47AK4C	Strong	Biomarker	[2164]
HNRNPDL	OTB3BFCV	Strong	Biomarker	[2164]
HNRNPL	OT0DJX74	Strong	Biomarker	[2165]
HNRNPM	OTFU3OEZ	Strong	Biomarker	[2166]
HNRNPUL2	OTJ6JTGT	Strong	Biomarker	[2167]
HOXA10	OTB6GQ09	Strong	Altered Expression	[2168]
HOXA2	OT6G6ZIK	Strong	Biomarker	[1558]
HOXA9	OTKNK5H0	Strong	Altered Expression	[1310]
HOXB6	OT3TFQ0U	Strong	Biomarker	[2169]
HOXB8	OTKHOD17	Strong	Biomarker	[2170]
HOXB9	OTMVHQOU	Strong	Biomarker	[2171]
HOXD13	OTWSC8TF	Strong	Biomarker	[2172]
HOXD8	OTJ5H7AT	Strong	Biomarker	[2173]
HPCA	OTERUPP6	Strong	Altered Expression	[2174]
HPS1	OTKS5I7T	Strong	Biomarker	[1707]
HRG	OTPLUFOG	Strong	Biomarker	[2175]
HSF4	OT1UX9SK	Strong	Biomarker	[2176]
HSPA12A	OTFOCDD6	Strong	Genetic Variation	[2177]
HSPA1A	OTKGIE76	Strong	Altered Expression	[2178]
HSPA1L	OTC2V1K6	Strong	Altered Expression	[1691]
HSPA2	OTSDET7B	Strong	Altered Expression	[2178]
HSPA4	OT5HR0AR	Strong	Biomarker	[2179]
HSPB2	OTS01646	Strong	Altered Expression	[2180]
HSPB6	OTFPLGZI	Strong	Altered Expression	[2181]
HSPH1	OTVRR73T	Strong	Biomarker	[2182]
HTRA3	OTXJ0H4X	Strong	Altered Expression	[2183]
HUWE1	OTFH6BJS	Strong	Biomarker	[2184]
IARS1	OT9WXH5N	Strong	Biomarker	[2185]
IBSP	OT29944Y	Strong	Biomarker	[2186]
IER3	OTZJI5FZ	Strong	Altered Expression	[2187]
IFNA1	OTPMKY0L	Strong	Biomarker	[2188]
IFNGR1	OTCTQBWW	Strong	Genetic Variation	[268]
IGDCC3	OTGR1KA4	Strong	Posttranslational Modification	[2189]
IGF2BP3	OTB97VIK	Strong	Biomarker	[1753]
IGFBP4	OT2HZRBD	Strong	Biomarker	[2190]
IHH	OT1DWGXC	Strong	Biomarker	[2191]
IKBKE	OT5VYOSM	Strong	Biomarker	[2192]
IL10RA	OTOX3D1D	Strong	Biomarker	[2193]
IL34	OTZ15VVK	Strong	Altered Expression	[2194]
IL6ST	OT1N9C70	Strong	Altered Expression	[2195]
IMMP1L	OTA6LOLR	Strong	Biomarker	[1319]
IMPACT	OTQ923OB	Strong	Genetic Variation	[2196]
ING1	OTEZBRKW	Strong	Genetic Variation	[2197]
ING2	OT6H0EWF	Strong	Biomarker	[2198]
ING4	OT0VVG4V	Strong	Altered Expression	[2199]
INHBB	OT2QLD11	Strong	Biomarker	[2200]
INPPL1	OTCDAVBQ	Strong	Biomarker	[2201]
INSIG2	OTX4VY51	Strong	Biomarker	[2202]
INSRR	OT3F75WA	Strong	Biomarker	[2203]
INTS1	OT7TY1M1	Strong	Biomarker	[2204]
IPO5	OTAK40ED	Strong	Biomarker	[2205]
IQCJ-SCHIP1	OTUJCNVL	Strong	Altered Expression	[2206]
IQGAP1	OTZRWTGA	Strong	Biomarker	[2207]
IQGAP2	OTX2UA7P	Strong	Altered Expression	[2208]
IRAK2	OT6Y1QZN	Strong	Genetic Variation	[2209]
IRF2	OTAZRUW3	Strong	Altered Expression	[2210]
IRF5	OT8SIIAP	Strong	Genetic Variation	[2211]
IRF6	OTKJ44EV	Strong	Altered Expression	[2212]
IRF7	OTC1A2PQ	Strong	Genetic Variation	[2211]
IRS4	OTTOL40K	Strong	Altered Expression	[2185]
IRX5	OT05J514	Strong	Altered Expression	[2213]
ISOC1	OTAO7Z87	Strong	Biomarker	[2214]
ISX	OTULQRWA	Strong	Genetic Variation	[2215]
ISYNA1	OT49ONSE	Strong	Biomarker	[934]
ITGA2B	OT4Y17PY	Strong	Biomarker	[2216]
ITGAX	OTOGIMHE	Strong	Biomarker	[2217]
ITPRID2	OTO3JDX5	Strong	Biomarker	[2218]
IVNS1ABP	OTYHL4I7	Strong	Biomarker	[2219]
JAG1	OT3LGT6K	Strong	Biomarker	[2220]
JAM3	OTX0F9QL	Strong	Biomarker	[2221]
JMJD8	OT4LA861	Strong	Biomarker	[2222]
JPH1	OTCAILYU	Strong	Altered Expression	[2223]
JRK	OTO8E77P	Strong	Altered Expression	[2224]
JUNB	OTG2JXV5	Strong	Biomarker	[1675]
JUND	OTNKACJD	Strong	Biomarker	[1675]
KAT7	OTUN98IC	Strong	Altered Expression	[2225]
KAT8	OT5LPQTR	Strong	Altered Expression	[2226]
KBTBD11	OTBOY3WH	Strong	Genetic Variation	[2227]
KCNIP4	OTB1BS0X	Strong	Genetic Variation	[1800]
KDM3B	OTZU5J5S	Strong	Biomarker	[2228]
KDM4D	OTN6KAE6	Strong	Biomarker	[2229]
KDM6A	OTZM3MJJ	Strong	Biomarker	[2230]
KIF20A	OTXOQHE0	Strong	Biomarker	[2231]
KIF22	OTY6X6BL	Strong	Biomarker	[1716]
KIF23	OTY850JC	Strong	Genetic Variation	[439]
KIF2A	OT2WQ6QD	Strong	Altered Expression	[2232]
KIF2C	OTJ8G3NP	Strong	Genetic Variation	[2233]
KIF3B	OT0HJREB	Strong	Altered Expression	[2234]
KL	OTD4VWU6	Strong	Biomarker	[2235]
KLF14	OT8BXLBS	Strong	Biomarker	[2236]
KLF2	OTIP1UFX	Strong	Biomarker	[215]
KLF3	OTIIAC18	Strong	Biomarker	[2236]
KLF5	OT1ABI9N	Strong	Altered Expression	[847]
KLF8	OTUC5CDB	Strong	Biomarker	[2237]
KLF9	OTBFEJRQ	Strong	Biomarker	[362]
KLK10	OTD573EL	Strong	Biomarker	[2238]
KLK12	OTNYK59J	Strong	Biomarker	[2239]
KLK15	OT7BVG17	Strong	Biomarker	[2240]
KMT2C	OTC59BCO	Strong	Genetic Variation	[2088]
KNL1	OT4Q3LHV	Strong	Biomarker	[2241]
KPNA2	OTU7FOE6	Strong	Altered Expression	[2242]
KPNA3	OTLI3TM2	Strong	Altered Expression	[2243]
KRIT1	OT58AP1I	Strong	Altered Expression	[1815]
KRT18	OTVLQFIP	Strong	Biomarker	[2244]
KRT23	OTQW6UAG	Strong	Altered Expression	[2245]
KRT6B	OTBXJYHY	Strong	Altered Expression	[693]
KRT7	OTLT3JFN	Strong	Biomarker	[2246]
KRT71	OTI91X9Z	Strong	Altered Expression	[2247]
KRT8	OTTM4X11	Strong	Biomarker	[2248]
KRT80	OTAU54U3	Strong	Biomarker	[2249]
L1TD1	OTB2W20Y	Strong	Genetic Variation	[294]
L3MBTL1	OT8M52QY	Strong	Biomarker	[2250]
LACTB	OTRWGNBF	Strong	Altered Expression	[2251]
LACTB2	OTU4IFBU	Strong	Altered Expression	[2252]
LAMA1	OTQZMP86	Strong	Biomarker	[2253]
LAMA3	OTFME7HT	Strong	Genetic Variation	[2254]
LAMB4	OT0NOOB2	Strong	Altered Expression	[2254]
LAMC1	OTIG527N	Strong	Genetic Variation	[364]
LAT	OTZC1XZ1	Strong	Biomarker	[293]
LAT2	OTWJDKIH	Strong	Biomarker	[2255]
LBR	OT1HG3HG	Strong	Biomarker	[2256]
LCP1	OTK61F2A	Strong	Genetic Variation	[2257]
LDB1	OT20EAPR	Strong	Biomarker	[2258]
LECT2	OTSFZ9JD	Strong	Biomarker	[2259]
LEF1	OTWS5I5H	Strong	Altered Expression	[2260]
LGALS12	OTNTQULB	Strong	Altered Expression	[2261]
LGALS4	OTKQCG0H	Strong	Biomarker	[2262]
LGALS9	OT7MF91K	Strong	Biomarker	[2263]
LGR6	OTPZ1PWR	Strong	Biomarker	[2264]
LIG3	OT48SKET	Strong	Biomarker	[2265]
LIG4	OT40DNXU	Strong	Biomarker	[2266]
LIMA1	OTONPC9R	Strong	Genetic Variation	[2267]
LMLN	OTQF0JPY	Strong	Biomarker	[321]
LMO1	OTB59SKB	Strong	Altered Expression	[2268]
LNPK	OTOBNX6G	Strong	Biomarker	[2269]
LNX1	OTZWFMAZ	Strong	Biomarker	[2270]
LNX2	OT3I0A91	Strong	Altered Expression	[2271]
LPCAT2	OT6NTBAA	Strong	Biomarker	[2272]
LPCAT4	OTCFJKLB	Strong	Altered Expression	[2273]
LPP	OT6TU8SE	Strong	Biomarker	[2274]
LRCH1	OT0RCL85	Strong	Altered Expression	[1966]
LRG1	OTLD0KWA	Strong	Biomarker	[155]
LRIT1	OTNEQPMZ	Strong	Biomarker	[450]
LRPPRC	OTXSK5LP	Strong	Altered Expression	[2195]
LRRC3B	OT9VDGPR	Strong	Biomarker	[2275]
LSAMP	OTYXVQX2	Strong	Genetic Variation	[989]
LTBP4	OTC8WL2V	Strong	Genetic Variation	[1766]
LUC7L3	OTKDED8A	Strong	Biomarker	[2276]
LUM	OTSRC874	Strong	Altered Expression	[2277]
LY6G6F	OT5W9Q4B	Strong	Altered Expression	[667]
LYRM2	OTET3S6H	Strong	Altered Expression	[2278]
LZTS1	OTXXL864	Strong	Biomarker	[1693]
MACC1	OTV3DLX0	Strong	Altered Expression	[2279]
MACF1	OTVIHD77	Strong	Genetic Variation	[2280]
MACROD1	OTWFEVRW	Strong	Biomarker	[2281]
MACROD2	OTNQCHC6	Strong	Biomarker	[2282]
MACROH2A2	OTAKSVYV	Strong	Altered Expression	[2283]
MAD2L1	OTXNGZCG	Strong	Genetic Variation	[723]
MAEL	OTZ2VU30	Strong	Altered Expression	[2284]
MAF	OT1GR3IZ	Strong	Biomarker	[215]
MAF1	OTKB0N8Q	Strong	Biomarker	[2285]
MAFG	OTBQFUZH	Strong	Genetic Variation	[2286]
MAGED2	OTMEWNSE	Strong	Biomarker	[1699]
MAGI2	OTXDDKZS	Strong	Biomarker	[1640]
MAK16	OTD546E5	Strong	Biomarker	[852]
MAL2	OTVPEI80	Strong	Biomarker	[2287]
MAMSTR	OT4J6Z7G	Strong	Genetic Variation	[1287]
MAP1LC3B	OTUYHB84	Strong	Biomarker	[2288]
MAP1LC3C	OTM4ECDK	Strong	Altered Expression	[2289]
MAP1S	OT5WUD4C	Strong	Biomarker	[2290]
MAP2K3	OTI2OREX	Strong	Biomarker	[2291]
MAP6	OTPUI00F	Strong	Biomarker	[2292]
MAPK13	OT0W9GE7	Strong	Biomarker	[2291]
MAPK8IP2	OTDUHLN0	Strong	Biomarker	[2293]
MARK1	OTP7KL47	Strong	Biomarker	[2294]
MASTL	OTQ7YKK5	Strong	Altered Expression	[2295]
MATN1	OTBRTCTQ	Strong	Altered Expression	[2296]
MAU2	OTALDF8Q	Strong	Genetic Variation	[2297]
MAX	OTKZ0YKM	Strong	Biomarker	[2298]
MCM2	OTGGORIQ	Strong	Biomarker	[739]
MCM4	OT19PNNG	Strong	Genetic Variation	[1530]
MCM9	OTALGFW8	Strong	Genetic Variation	[2299]
MCPH1	OTYT3TT5	Strong	Genetic Variation	[2300]
MCRS1	OT8K2X8P	Strong	Biomarker	[2301]
MDFI	OTIA6YUG	Strong	Biomarker	[2302]
MECOM	OTP983W8	Strong	Genetic Variation	[2303]
MECR	OTJQ5XKQ	Strong	Biomarker	[2304]
MED1	OTOO24C4	Strong	Altered Expression	[834]
MED13	OTP5LEJE	Strong	Genetic Variation	[2305]
MED19	OTT9RT5N	Strong	Biomarker	[2306]
MED28	OTEDM1L5	Strong	Biomarker	[2307]
MEF2A	OTV2SF6E	Strong	Altered Expression	[2308]
MEF2D	OT7CEIG0	Strong	Biomarker	[2309]
MEGF6	OTEUYTP1	Strong	Biomarker	[2310]
MEGF8	OT5G38CH	Strong	Biomarker	[2311]
MEIS1	OTH9DKAD	Strong	Altered Expression	[2312]
METTL16	OT99VP8Y	Strong	Altered Expression	[2313]
METTL3	OTSXP1M3	Strong	Biomarker	[2314]
MEX3C	OT8AJG1I	Strong	Biomarker	[2315]
MFAP1	OTZN4FT3	Strong	Altered Expression	[777]
MFAP3	OTFAU0YL	Strong	Biomarker	[2316]
MFAP3L	OTNMHSAH	Strong	Biomarker	[2316]
MFAP5	OT46VXSG	Strong	Biomarker	[2118]
MFHAS1	OTS922CJ	Strong	Biomarker	[2317]
MFSD14B	OTAYTUQM	Strong	Genetic Variation	[2318]
MFSD4B	OTHHKWRT	Strong	Genetic Variation	[380]
MIA3	OTBVIZQD	Strong	Biomarker	[2319]
MICAL2	OT04OQQJ	Strong	Altered Expression	[2320]
MIEF1	OTFSP3FS	Strong	Biomarker	[698]
MIEN1	OTCQ8DAD	Strong	Altered Expression	[2321]
MIER3	OTL5BGOB	Strong	Biomarker	[2322]
MIIP	OT79EXZ7	Strong	Biomarker	[2323]
MIP	OTEBLU3E	Strong	Biomarker	[2324]
MLLT10	OTURMDV7	Strong	Biomarker	[918]
MLLT11	OTG5RVHC	Strong	Biomarker	[2325]
MLN	OTBZ5SE5	Strong	Biomarker	[842]
MMP19	OTLSTT2B	Strong	Altered Expression	[2326]
MN1	OTVQR4R9	Strong	Altered Expression	[2327]
MNAT1	OTXLOYCB	Strong	Biomarker	[2328]
MNX1	OTXP9FH1	Strong	Biomarker	[2329]
MOB1A	OTSPBZ4Z	Strong	Altered Expression	[2330]
MORC2	OT52A8BJ	Strong	Biomarker	[2331]
MPG	OTAHW80B	Strong	Altered Expression	[2332]
MPHOSPH8	OTYI2WNS	Strong	Biomarker	[2333]
MPRIP	OT5FV5NS	Strong	Biomarker	[1496]
MRE11	OTGU8TZM	Strong	Biomarker	[2334]
MRGBP	OTXBPDMS	Strong	Biomarker	[2335]
MRGPRX3	OTRKCCDS	Strong	Genetic Variation	[588]
MRGPRX4	OTOBHZVA	Strong	Genetic Variation	[588]
MRPL28	OT4LUTZU	Strong	Biomarker	[1854]
MRPL41	OTG5URO4	Strong	Altered Expression	[2336]
MRPL43	OTM12XS9	Strong	Genetic Variation	[2337]
MRPL58	OTPTWLZY	Strong	Biomarker	[2338]
MSX1	OT5U41ZP	Strong	Altered Expression	[2339]
MT1G	OTAV1OCR	Strong	Altered Expression	[2340]
MTG1	OTC9U1LI	Strong	Altered Expression	[2341]
MTHFD1	OTMKHVWC	Strong	Genetic Variation	[2342]
MTHFD1L	OTV01EFP	Strong	Biomarker	[2343]
MTHFD2	OT1LQSGX	Strong	Biomarker	[2344]
MTMR11	OTHL2O08	Strong	Biomarker	[2276]
MTMR7	OT47NVYM	Strong	Biomarker	[2345]
MTSS1	OT5DTDO2	Strong	Altered Expression	[2346]
MTUS1	OTBPALMU	Strong	Genetic Variation	[2347]
MTX1	OTLSDNZO	Strong	Genetic Variation	[607]
MUC3A	OTI4XUDY	Strong	Altered Expression	[118]
MUC4	OTLT11V1	Strong	Biomarker	[2348]
MUC6	OTPVL723	Strong	Biomarker	[2349]
MUC7	OTSTMP0X	Strong	Genetic Variation	[756]
MUL1	OT2JC9YR	Strong	Biomarker	[374]
MYCL	OT1MFQ5U	Strong	Genetic Variation	[2350]
MYH6	OT3YNCH1	Strong	Altered Expression	[2351]
MYH7B	OTCB2IJB	Strong	Genetic Variation	[1582]
MYH9	OT94Z706	Strong	Biomarker	[2352]
MYNN	OT61R1HP	Strong	Genetic Variation	[2353]
MYO10	OTHB78ZQ	Strong	Biomarker	[2354]
MYO16	OTMS3D8W	Strong	Genetic Variation	[1800]
MYO5A	OTMWLP3E	Strong	Biomarker	[2355]
MYO5B	OTCKL3W3	Strong	Biomarker	[2355]
MYO6	OTJQYRC7	Strong	Biomarker	[2356]
MYRF	OTKF6AEB	Strong	Genetic Variation	[294]
MYSM1	OTO73N00	Strong	Altered Expression	[2357]
MZF1	OTMVZCPW	Strong	Genetic Variation	[215]
NAP1L2	OT8QI4GF	Strong	Biomarker	[2358]
NARS1	OTFS4J1W	Strong	Biomarker	[1753]
NAV2	OTGAOL01	Strong	Altered Expression	[2359]
NAXE	OTRZPISQ	Strong	Biomarker	[2360]
NBEAL2	OTMCAXWR	Strong	Biomarker	[2361]
NCF4	OTX007YL	Strong	Genetic Variation	[2362]
NCKIPSD	OT24UORN	Strong	Biomarker	[1676]
NCOA1	OTLIUJQD	Strong	Altered Expression	[834]
NCOA2	OTMQFPBB	Strong	Biomarker	[2252]
NCOA5	OTOGWTWB	Strong	Biomarker	[2363]
NCOR1	OT04XNOU	Strong	Altered Expression	[834]
ND1	OTCLGIXV	Strong	Biomarker	[2219]
ND2	OTG9OHOX	Strong	Genetic Variation	[2364]
NDC80	OTS7D306	Strong	Biomarker	[495]
NDN	OTYBYJ82	Strong	Biomarker	[2365]
NDRG1	OTVO66BO	Strong	Biomarker	[2331]
NDRG2	OT5L6KD7	Strong	Altered Expression	[2366]
NDRG4	OTJBOTD8	Strong	Biomarker	[273]
NDST4	OTEKG7JJ	Strong	Biomarker	[2367]
NDUFA4	OTDVH3QG	Strong	Altered Expression	[2368]
NDUFA4L2	OTK0PG7R	Strong	Altered Expression	[2369]
NEK10	OTN0JAYL	Strong	Genetic Variation	[607]
NEK11	OTMYENTC	Strong	Biomarker	[2370]
NEK4	OTOB8366	Strong	Altered Expression	[2371]
NELFCD	OTOLTZPU	Strong	Altered Expression	[2372]
NELL2	OTS4MJZ7	Strong	Altered Expression	[2373]
NEURL1	OT2C4P70	Strong	Biomarker	[1479]
NF1	OTC29NHH	Strong	Genetic Variation	[2374]
NFATC1	OT4TMERS	Strong	Altered Expression	[2375]
NFATC2	OTK5T6HZ	Strong	Biomarker	[2376]
NFATC3	OTYOORME	Strong	Biomarker	[1395]
NFE2L3	OT1MGXT0	Strong	Altered Expression	[2377]
NFIB	OTX94PD0	Strong	Biomarker	[2378]
NFYB	OTXSE7KW	Strong	Altered Expression	[2379]
NHS	OTKE8QAT	Strong	Genetic Variation	[2380]
NINJ2	OTUG1AOV	Strong	Biomarker	[2381]
NIT1	OT1KHPKJ	Strong	Biomarker	[2382]
NKD2	OTCYT3I6	Strong	Biomarker	[2383]
NLK	OT2LETFS	Strong	Biomarker	[2384]
NLRC3	OTWLLFFN	Strong	Biomarker	[2385]
NLRC4	OTAIA3NA	Strong	Biomarker	[2386]
NME2	OTCYGLHV	Strong	Biomarker	[1150]
NME6	OTJNKOFA	Strong	Genetic Variation	[2387]
NMU	OTW9X7BQ	Strong	Biomarker	[2388]
NOB1	OTW0YNSL	Strong	Altered Expression	[2389]
NOC3L	OTYOR3PV	Strong	Genetic Variation	[2390]
NOMO1	OTIALEI1	Strong	Biomarker	[2391]
NONO	OTN36Q6U	Strong	Biomarker	[2392]
NOTUM	OT03MYQ2	Strong	Altered Expression	[2393]
NOX1	OTZPJQCC	Strong	Biomarker	[864]
NPAS2	OTMRT2TS	Strong	Biomarker	[2394]
NR2C2	OTDZWVOJ	Strong	Biomarker	[729]
NR2F2	OTJFS67N	Strong	Altered Expression	[1896]
NRBP1	OTRWEJ65	Strong	Biomarker	[2395]
NRCAM	OT80HHQ2	Strong	Biomarker	[1484]
NRDC	OTWBBCXO	Strong	Altered Expression	[2396]
NRIP2	OTLKYGW4	Strong	Biomarker	[2397]
NSD2	OTQ6SW4R	Strong	Biomarker	[2220]
NSD3	OT3677ZG	Strong	Altered Expression	[2398]
NSG1	OTRIMA50	Strong	Altered Expression	[2399]
NTHL1	OTPQXPT1	Strong	Genetic Variation	[2400]
NTN4	OTDRRMP3	Strong	Biomarker	[2401]
NTNG1	OTF48IID	Strong	Biomarker	[2402]
NTS	OTPGDNQS	Strong	Biomarker	[862]
NUBP1	OTE8RAKZ	Strong	Biomarker	[2403]
NUBPL	OTQMCSXT	Strong	Altered Expression	[2404]
NUCB2	OTHO6JWN	Strong	Altered Expression	[2405]
NUDCD1	OT8DS3CX	Strong	Biomarker	[2406]
NUDT5	OTHYCBA6	Strong	Biomarker	[2407]
NUMB	OTMB586Q	Strong	Biomarker	[2270]
NUP153	OTCAS0AR	Strong	Altered Expression	[2408]
NUP62	OTMN63DH	Strong	Biomarker	[680]
NUP88	OT647WOR	Strong	Altered Expression	[2409]
NUP98	OTNT12G2	Strong	Biomarker	[1664]
NUSAP1	OT85HIJ5	Strong	Biomarker	[2410]
NWD1	OT4JMFPH	Strong	Biomarker	[2411]
NXF2	OTJS5KTH	Strong	Biomarker	[2412]
NXN	OT35N40G	Strong	Genetic Variation	[215]
NXPE4	OTWDLYH5	Strong	Biomarker	[2413]
NXT1	OT0VO6AY	Strong	Biomarker	[1854]
OAS2	OT64CCTM	Strong	Biomarker	[2414]
OBP2A	OTBIJ5TI	Strong	Biomarker	[2415]
OBSCN	OTT14OVX	Strong	Genetic Variation	[2416]
OCA2	OTDWIGBF	Strong	Biomarker	[2417]
OCLN	OTSUTVWL	Strong	Biomarker	[2418]
ODAM	OTT666SJ	Strong	Biomarker	[2419]
OGN	OTKP5S4L	Strong	Altered Expression	[2420]
OLFM1	OTOYPEWW	Strong	Biomarker	[2421]
ONECUT1	OTK1QUQT	Strong	Biomarker	[2422]
OPN1LW	OTFNUZ7O	Strong	Biomarker	[405]
OR1J2	OTIQTQHU	Strong	Genetic Variation	[1800]
OR7C1	OTQKD84O	Strong	Altered Expression	[2423]
OTOP2	OTDXHLKN	Strong	Posttranslational Modification	[2424]
OTUB1	OT8WWM9O	Strong	Biomarker	[2425]
OVOL2	OTFM1GKF	Strong	Altered Expression	[2426]
P2RX5	OTLBR20R	Strong	Biomarker	[271]
PA2G4	OT7IG7HT	Strong	Biomarker	[2427]
PACC1	OTKBS8CC	Strong	Biomarker	[2428]
PACS2	OTPU9HUA	Strong	Biomarker	[2429]
PADI2	OTT40K94	Strong	Biomarker	[2430]
PAEP	OTQA0NV4	Strong	Biomarker	[2431]
PAG1	OTFOJUIQ	Strong	Biomarker	[405]
PAICS	OTMZN747	Strong	Biomarker	[2432]
PALD1	OTLGUM8H	Strong	Altered Expression	[2433]
PALLD	OTZ2MUJZ	Strong	Altered Expression	[2433]
PARD3	OTH5BPLO	Strong	Biomarker	[2434]
PARM1	OTDNK7EX	Strong	Biomarker	[2413]
PARP6	OTWSXW4O	Strong	Altered Expression	[2435]
PARVB	OT9OGVWX	Strong	Altered Expression	[2436]
PASD1	OTZZWR7L	Strong	Biomarker	[606]
PBX3	OT8WMVM4	Strong	Posttranslational Modification	[2437]
PCBP1	OTHN0TD7	Strong	Biomarker	[2438]
PCBP4	OTDLL4NB	Strong	Biomarker	[405]
PCDH17	OTRK0M05	Strong	Biomarker	[2439]
PCDH18	OTTLQWRN	Strong	Altered Expression	[2440]
PCDHB3	OTEDVXZY	Strong	Biomarker	[2441]
PCDHGA7	OTDW7R39	Strong	Altered Expression	[2442]
PCLAF	OTMVIOUU	Strong	Biomarker	[2443]
PCNX1	OTFP8XHC	Strong	Genetic Variation	[2280]
PDC	OT1UUVYY	Strong	Biomarker	[2444]
PDCD10	OTCHJTSF	Strong	Biomarker	[2445]
PDCD6IP	OTS8T6A7	Strong	Biomarker	[1640]
PDGFRL	OTJPRECT	Strong	Biomarker	[2446]
PDIA3	OTHPQ0Q3	Strong	Altered Expression	[2447]
PDK4	OTCMHMBZ	Strong	Biomarker	[2448]
PDLIM2	OTEURRPD	Strong	Altered Expression	[2449]
PDLIM7	OTAZVODU	Strong	Altered Expression	[2450]
PDPN	OTBUV19I	Strong	Altered Expression	[2451]
PDS5B	OT3U3X8Z	Strong	Genetic Variation	[913]
PENK	OT8P3HMP	Strong	Biomarker	[2452]
PER2	OTU2B1DJ	Strong	Altered Expression	[2453]
PES1	OTMZK7XE	Strong	Biomarker	[2454]
PFDN1	OT9837QM	Strong	Altered Expression	[2455]
PFDN4	OT5NRHER	Strong	Altered Expression	[2456]
PFN1	OTHTGA1H	Strong	Biomarker	[2457]
PFN2	OT5SSSA7	Strong	Biomarker	[2458]
PGAM5	OT6Q5M0C	Strong	Biomarker	[2459]
PHB2	OTCAX3AW	Strong	Altered Expression	[2460]
PHF2	OTJCIQR2	Strong	Biomarker	[2461]
PHF6	OT8DXI40	Strong	Altered Expression	[2462]
PHGR1	OTY3GTEP	Strong	Altered Expression	[2463]
PHKB	OTKXZZIU	Strong	Altered Expression	[2464]
PHLDB2	OTDKMB2G	Strong	Biomarker	[2465]
PI3	OT47MTC3	Strong	Altered Expression	[2466]
PIGK	OTAFSYLD	Strong	Altered Expression	[2467]
PIGN	OTHHTJKX	Strong	Biomarker	[2315]
PIK3R1	OT5BZ1J9	Strong	Biomarker	[1202]
PIK3R3	OTXGJ8N1	Strong	Biomarker	[2468]
PINK1	OT50NR57	Strong	Altered Expression	[2469]
PIPOX	OTWTCOTN	Strong	Biomarker	[2470]
PITPNM1	OTIUYAG5	Strong	Biomarker	[2471]
PITX1	OTA0UN4C	Strong	Biomarker	[2472]
PIWIL1	OT7CRGZ3	Strong	Biomarker	[2473]
PIWIL2	OT1PXQIF	Strong	Altered Expression	[2474]
PKD1	OT5ALRZ5	Strong	Biomarker	[693]
PKD1L2	OTVDFDED	Strong	Genetic Variation	[2475]
PKD2	OTIXBU8H	Strong	Altered Expression	[693]
PKHD1	OTAH8SMF	Strong	Genetic Variation	[2476]
PLA2G3	OT3K7TMY	Strong	Biomarker	[2477]
PLA2G6	OT5FL0WU	Strong	Genetic Variation	[823]
PLAAT3	OTVXXJ5K	Strong	Genetic Variation	[2478]
PLAAT4	OTI66SAJ	Strong	Biomarker	[248]
PLAGL1	OTZAO900	Strong	Altered Expression	[2479]
PLAGL2	OT6AP4V2	Strong	Biomarker	[251]
PLB1	OTZ6TTYV	Strong	Altered Expression	[2480]
PLCD1	OT6WFVXZ	Strong	Biomarker	[2481]
PLCH1	OT6Z1L2E	Strong	Genetic Variation	[2482]
PLCL1	OTJL2C79	Strong	Genetic Variation	[2483]
PLEKHG6	OTZWA27A	Strong	Genetic Variation	[215]
PLK3	OT19CT2Z	Strong	Altered Expression	[2484]
PMAIP1	OTXEE550	Strong	Biomarker	[2485]
PMEPA1	OTY8Z9UF	Strong	Biomarker	[2486]
PNKD	OT6G9UXN	Strong	Genetic Variation	[364]
PODXL	OTPNQXF3	Strong	Biomarker	[2219]
POGLUT1	OTDX7GZD	Strong	Altered Expression	[2487]
POLE	OTFM3MMU	Strong	Genetic Variation	[2488]
POLR2A	OTHJQ1DZ	Strong	Altered Expression	[2489]
POLR2B	OTS3F0H2	Strong	Biomarker	[1875]
POT1	OTNBXJCQ	Strong	Altered Expression	[2490]
POTEA	OTE690XR	Strong	Genetic Variation	[1582]
POTED	OTAUSTUK	Strong	Altered Expression	[2491]
POTEE	OTSQ6J24	Strong	Biomarker	[2491]
POTEF	OTV3WXYE	Strong	Altered Expression	[70]
POU2F2	OTPV0J0C	Strong	Biomarker	[931]
POU5F1B	OT0FKQ51	Strong	Genetic Variation	[364]
PPA1	OTHZK1QB	Strong	Altered Expression	[2492]
PPARGC1A	OTHCDQ22	Strong	Genetic Variation	[2493]
PPBP	OT1FHGQS	Strong	Biomarker	[926]
PPIG	OTZ8BTTM	Strong	Genetic Variation	[2494]
PPL	OTTM4WDO	Strong	Biomarker	[2495]
PPM1H	OTKSVU7S	Strong	Biomarker	[2496]
PPP1R12A	OT4AVU95	Strong	Biomarker	[2497]
PPP1R12B	OTONIS87	Strong	Biomarker	[589]
PPP1R14A	OTQODWZB	Strong	Biomarker	[2037]
PPP1R1A	OTGTAGCV	Strong	Biomarker	[2498]
PPP1R1B	OTSIJMQ9	Strong	Altered Expression	[2499]
PPP1R21	OTWN6N7T	Strong	Genetic Variation	[294]
PPP1R3C	OTEU05TX	Strong	Posttranslational Modification	[1993]
PPP1R9B	OTDCTHTT	Strong	Altered Expression	[2500]
PPP2R2A	OT9297OG	Strong	Biomarker	[2501]
PPP2R5E	OT8GPFT5	Strong	Biomarker	[2502]
PRDM14	OTWZKY4L	Strong	Altered Expression	[2503]
PRDX1	OTZ3BEC4	Strong	Altered Expression	[2504]
PRDX2	OTLWCY9T	Strong	Genetic Variation	[2505]
PRDX6	OTS8KC8A	Strong	Biomarker	[2506]
PREX1	OTUTPVA9	Strong	Genetic Variation	[294]
PRKAA1	OT7TNF0L	Strong	Biomarker	[2507]
PRKAA2	OTU1KZPV	Strong	Biomarker	[2508]
PRKAB1	OT1OG4QZ	Strong	Biomarker	[2508]
PRKACB	OT6RMDCE	Strong	Altered Expression	[670]
PRKN	OTJBN41W	Strong	Biomarker	[374]
PRLHR	OT1THGOP	Strong	Genetic Variation	[2177]
PRPF31	OTSJ0Z1Y	Strong	Genetic Variation	[2509]
PRPF4	OTK0XRQN	Strong	Altered Expression	[2510]
PRPS1	OTN3A6CN	Strong	Altered Expression	[2511]
PRR5	OTYHSGJL	Strong	Genetic Variation	[2512]
PRRT2	OTCJUBDO	Strong	Biomarker	[843]
PRRX1	OTTZK5G8	Strong	Biomarker	[2513]
PRSS55	OTXXWI5Y	Strong	Altered Expression	[1914]
PSMA7	OTPHI6ST	Strong	Biomarker	[2514]
PSMA8	OTR8R6Y6	Strong	Genetic Variation	[1582]
PSMC2	OTJ4V337	Strong	Altered Expression	[2515]
PSME3	OTSTC4YY	Strong	Altered Expression	[2516]
PSPH	OTV1PVAX	Strong	Biomarker	[2517]
PTBP2	OTF4S7NE	Strong	Biomarker	[2518]
PTBP3	OTVVYKIF	Strong	Altered Expression	[2519]
PTPA	OTRGFOI7	Strong	Biomarker	[2520]
PTPN12	OT5WA666	Strong	Genetic Variation	[1108]
PTPN3	OTSLZBVY	Strong	Altered Expression	[2521]
PTPN4	OT6SXU5Y	Strong	Biomarker	[2522]
PTPRA	OTZA82J1	Strong	Biomarker	[888]
PTPRD	OTZPJ3GX	Strong	Biomarker	[1484]
PTPRG	OT9N2WOF	Strong	Posttranslational Modification	[2523]
PTPRH	OTDUHQGF	Strong	Altered Expression	[2524]
PTPRK	OTAP5AT3	Strong	Biomarker	[2525]
PTPRO	OTFLKWOY	Strong	Biomarker	[2526]
PTPRR	OT790UA2	Strong	Biomarker	[2527]
PTPRT	OTV5TXNN	Strong	Biomarker	[2528]
PTPRU	OTHDO0QG	Strong	Genetic Variation	[1108]
PTTG1	OTIMYS4W	Strong	Biomarker	[2529]
PTX3	OTPXHRKU	Strong	Biomarker	[2530]
PUDP	OTEPEJLX	Strong	Biomarker	[2531]
PUF60	OTG90DYF	Strong	Altered Expression	[2013]
PVR	OT3N91T7	Strong	Altered Expression	[2532]
PXN	OTVMMUOF	Strong	Altered Expression	[2533]
PYCARD	OT67RON3	Strong	Posttranslational Modification	[2534]
PYCR1	OTQHB52T	Strong	Altered Expression	[2535]
QKI	OTTAUGLB	Strong	Altered Expression	[2536]
QTRT1	OTC33MCV	Strong	Genetic Variation	[356]
RAB11FIP2	OTTX9RWE	Strong	Biomarker	[2537]
RAB11FIP4	OTIGHER7	Strong	Biomarker	[2538]
RAB11FIP5	OTNA33DE	Strong	Genetic Variation	[1582]
RAB14	OTF1J0TB	Strong	Biomarker	[559]
RAB1A	OTKPHRD0	Strong	Altered Expression	[2539]
RAB1B	OTAFCUAS	Strong	Biomarker	[2540]
RAB21	OTH3WGLG	Strong	Biomarker	[2541]
RAB23	OTBAKFBR	Strong	Biomarker	[2542]
RAB25	OTW0W6NP	Strong	Altered Expression	[2355]
RAB27A	OT9SQRWY	Strong	Altered Expression	[2543]
RAB3GAP1	OT4DQ8F2	Strong	Posttranslational Modification	[858]
RAB40B	OTCA9ZF5	Strong	Biomarker	[2544]
RAB5A	OTFR2KM4	Strong	Biomarker	[2545]
RAB8A	OTPB54Y3	Strong	Altered Expression	[2546]
RABGEF1	OTWC3Z3R	Strong	Altered Expression	[2547]
RACGAP1	OTQE8IEH	Strong	Altered Expression	[2548]
RAD18	OTQ9PLNT	Strong	Altered Expression	[2549]
RAD21	OTQS84ZF	Strong	Biomarker	[623]
RAD50	OTYMU9G1	Strong	Biomarker	[2550]
RAD51B	OTCJVRMY	Strong	Genetic Variation	[607]
RAD51C	OTUD6SY5	Strong	Altered Expression	[1756]
RAD52	OT0OTDHI	Strong	Genetic Variation	[2551]
RAD54B	OTMWB2P2	Strong	Biomarker	[2552]
RAI2	OTR8LX4J	Strong	Posttranslational Modification	[2553]
RALY	OT78NNWY	Strong	Genetic Variation	[607]
RAMP3	OTX6XLLM	Strong	Biomarker	[2554]
RAN	OT2TER5M	Strong	Genetic Variation	[2555]
RANBP2	OTFG5CVF	Strong	Biomarker	[2556]
RAP2B	OTD2NDQP	Strong	Altered Expression	[2557]
RASAL2	OTGMMX6W	Strong	Biomarker	[2558]
RASD1	OT2BAJHK	Strong	Altered Expression	[1603]
RASGRF1	OTNWJ7EN	Strong	Biomarker	[1449]
RASGRF2	OT67DAGF	Strong	Biomarker	[2559]
RASSF10	OTGB7EBG	Strong	Biomarker	[2560]
RASSF2	OT2JHDO4	Strong	Posttranslational Modification	[2561]
RASSF6	OT25GVWY	Strong	Biomarker	[2562]
RASSF8	OTXKGIB3	Strong	Altered Expression	[2563]
RB1CC1	OTZK8PFX	Strong	Biomarker	[1749]
RBFOX1	OTFPKEL7	Strong	Biomarker	[2564]
RBL2	OTBQSOE6	Strong	Posttranslational Modification	[858]
RBM3	OTAJ7R31	Strong	Biomarker	[2565]
RBM47	OT6W67VM	Strong	Altered Expression	[2566]
RBMS3	OTFSC9MR	Strong	Biomarker	[852]
REG1A	OTMHUH1D	Strong	Genetic Variation	[1108]
REG1B	OTSC2133	Strong	Altered Expression	[2567]
RELN	OTLKMW1O	Strong	Biomarker	[2568]
RETREG1	OTYOSLZX	Strong	Biomarker	[2569]
RETREG3	OTEUQ2MI	Strong	Genetic Variation	[989]
REV3L	OT0OP8EJ	Strong	Genetic Variation	[380]
RFPL4A	OTROUM09	Strong	Biomarker	[2570]
RGMB	OT2DROYU	Strong	Biomarker	[2571]
RGN	OTD04KB1	Strong	Altered Expression	[2572]
RGPD2	OTMUZ0HX	Strong	Biomarker	[2556]
RGS1	OTGXJYMG	Strong	Biomarker	[1990]
RGS17	OT5RVUDS	Strong	Altered Expression	[2573]
RHBDD1	OTL5J132	Strong	Biomarker	[2574]
RHBDD2	OTX54ILM	Strong	Altered Expression	[2575]
RHEB	OTFLTSEC	Strong	Altered Expression	[2576]
RHOC	OTOLE1FT	Strong	Biomarker	[2577]
RHOH	OT1J9SEB	Strong	Biomarker	[2578]
RHOQ	OTUBTU57	Strong	Altered Expression	[2579]
RING1	OTCWTAX0	Strong	Biomarker	[2580]
RINT1	OTMO19ZD	Strong	Altered Expression	[2581]
RIOX1	OTN41QXP	Strong	Altered Expression	[2582]
RIOX2	OT2YFPI2	Strong	Biomarker	[2583]
RIPOR3	OTHZ4RKK	Strong	Genetic Variation	[215]
RNASE1	OTKZ7CO9	Strong	Biomarker	[2584]
RNASE3	OTVE2XD1	Strong	Altered Expression	[1979]
RNASEH2C	OTJL9ZRN	Strong	Biomarker	[2585]
RNF146	OTE4CO7E	Strong	Biomarker	[2586]
RNF152	OTF8I14F	Strong	Biomarker	[2587]
RNF182	OT08FLHZ	Strong	Biomarker	[431]
RNF183	OTWPNZF9	Strong	Biomarker	[2588]
RNF20	OT9NK6ZT	Strong	Biomarker	[2589]
RNF216	OTR1XEZ3	Strong	Biomarker	[2590]
RNF26	OTPXA60S	Strong	Altered Expression	[2591]
RNF4	OTCMXQRE	Strong	Genetic Variation	[1800]
RNGTT	OT59E0KX	Strong	Genetic Variation	[989]
ROBO2	OTFJ9FQW	Strong	Altered Expression	[2592]
ROBO3	OTPVG40S	Strong	Biomarker	[248]
ROMO1	OTIEYVBW	Strong	Biomarker	[2593]
ROPN1L	OTRWZJ68	Strong	Genetic Variation	[356]
RPA1	OT76POLP	Strong	Biomarker	[2594]
RPA3	OT8JAQGL	Strong	Altered Expression	[2595]
RPL17	OTTYMPS6	Strong	Biomarker	[950]
RPL22L1	OTNWGF5C	Strong	Biomarker	[1428]
RPL23	OTXI1YLM	Strong	Altered Expression	[2596]
RPL27A	OTQQHPL0	Strong	Biomarker	[1998]
RPL29	OTUFIBJL	Strong	Biomarker	[2597]
RPL9	OTKE01O8	Strong	Biomarker	[2598]
RPLP0	OT3XKD6Y	Strong	Biomarker	[835]
RPN2	OTJ1SKOA	Strong	Altered Expression	[2599]
RPS18	OTFO45UM	Strong	Altered Expression	[864]
RPS24	OTSNKIL5	Strong	Genetic Variation	[2600]
RPS27L	OTZWHU0N	Strong	Altered Expression	[2601]
RPS6	OTT4D1LN	Strong	Biomarker	[2602]
RPS7	OTIK25WI	Strong	Biomarker	[2603]
RPTOR	OT4TQZ9F	Strong	Altered Expression	[2604]
RRAS	OTBBF28C	Strong	Biomarker	[1985]
RRBP1	OT4ZTPTM	Strong	Altered Expression	[2605]
RRM2B	OTE8GBUR	Strong	Altered Expression	[2606]
RRS1	OTTNCZN6	Strong	Altered Expression	[2607]
RSPO2	OT3HHXU0	Strong	Altered Expression	[889]
RTEL1	OTI3PJCT	Strong	Genetic Variation	[215]
RTKN2	OTV2AXQM	Strong	Genetic Variation	[2608]
RTN4RL2	OTSY5NQ9	Strong	Altered Expression	[2609]
RUFY3	OTMA4YA4	Strong	Altered Expression	[2610]
RUNX1T1	OT30DED5	Strong	Biomarker	[2611]
RYR3	OT4EHIP4	Strong	Genetic Variation	[2612]
S100A11	OTI57KDN	Strong	Altered Expression	[2613]
S100A16	OT3ERKQI	Strong	Altered Expression	[2614]
SALL1	OTYYZGLH	Strong	Posttranslational Modification	[1632]
SALL4	OTC08PR5	Strong	Altered Expression	[2615]
SAMHD1	OTBCIBC7	Strong	Biomarker	[2585]
SAPCD2	OTXS0EXM	Strong	Biomarker	[2616]
SAR1B	OT0JZOMY	Strong	Biomarker	[2617]
SASS6	OT1V8H40	Strong	Altered Expression	[2618]
SAT2	OT28QL7H	Strong	Genetic Variation	[2619]
SATB2	OT2W80XC	Strong	Altered Expression	[2620]
SBF1	OTW6I9RV	Strong	Biomarker	[2155]
SBF2	OTBB8NO8	Strong	Genetic Variation	[1287]
SBSPON	OTBHAW5K	Strong	Biomarker	[2621]
SCAF8	OTSCFMK3	Strong	Genetic Variation	[989]
SCG5	OTXSJMT1	Strong	Genetic Variation	[2622]
SCGB2A1	OT9L87U9	Strong	Altered Expression	[2623]
SCIN	OT6U09OL	Strong	Biomarker	[2624]
SCN7A	OTK05PXY	Strong	Altered Expression	[1109]
SCO2	OTJQQDRS	Strong	Altered Expression	[1039]
SCTR	OTC80IMR	Strong	Posttranslational Modification	[390]
SCYL3	OTRBBDHH	Strong	Genetic Variation	[2625]
SDF4	OTQ7WFYW	Strong	Biomarker	[1480]
SDHB	OTRE1M1T	Strong	Biomarker	[2626]
SDHC	OTC8G2MX	Strong	Genetic Variation	[2627]
SEC11A	OT06L834	Strong	Altered Expression	[2628]
SEC23A	OTBRNIJ3	Strong	Altered Expression	[2629]
SEC24C	OTMTJBQ1	Strong	Altered Expression	[2630]
SELENBP1	OT3NZNTR	Strong	Altered Expression	[2631]
SELENOS	OTUEWIU9	Strong	Genetic Variation	[2632]
SEMA3C	OTEGUY7F	Strong	Genetic Variation	[2088]
SEMA3D	OTD5TJV1	Strong	Altered Expression	[2633]
SEMA3E	OTD4S36H	Strong	Biomarker	[2634]
SEMA3F	OTQFMS8S	Strong	Biomarker	[2635]
SEMA4G	OT7BCPU7	Strong	Genetic Variation	[2337]
SEPHS1	OTZ19I59	Strong	Altered Expression	[1388]
SEPTIN7	OTJI08YX	Strong	Biomarker	[1433]
SERPINB9	OTJ811IF	Strong	Altered Expression	[2636]
SERPINE2	OTYF5340	Strong	Biomarker	[2637]
SERPINI1	OTUJHIJW	Strong	Biomarker	[2638]
SESN2	OT889IXY	Strong	Biomarker	[2639]
SET	OTGYYQJO	Strong	Altered Expression	[2640]
SETBP1	OTKGCOSR	Strong	Altered Expression	[2520]
SETDB1	OTWVUA1B	Strong	Altered Expression	[2641]
SETDB2	OTBVVP9Q	Strong	Genetic Variation	[614]
SFPQ	OTLCIAPJ	Strong	Biomarker	[2642]
SFRP1	OT0U9G41	Strong	Genetic Variation	[2643]
SFRP5	OTLCVVSH	Strong	Altered Expression	[2644]
SFT2D3	OT0IEAAR	Strong	Altered Expression	[2645]
SGMS2	OT3NHO99	Strong	Biomarker	[2646]
SH2B1	OTJZO2CI	Strong	Altered Expression	[2647]
SH3PXD2A	OTYRQJIH	Strong	Biomarker	[1527]
SH3TC1	OT0HYZIU	Strong	Biomarker	[1484]
SHBG	OTPWU5IW	Strong	Altered Expression	[2648]
SHISA3	OTE8TPCP	Strong	Genetic Variation	[2649]
SHOC2	OTUNQ2CT	Strong	Biomarker	[2650]
SHROOM2	OTZ2FJ7Q	Strong	Genetic Variation	[1287]
SIAH1	OT29A838	Strong	Biomarker	[2043]
SIGLEC6	OTO4F5C9	Strong	Altered Expression	[2651]
SIGLEC9	OTZC7SIM	Strong	Altered Expression	[2652]
SIPA1	OTXY5RXC	Strong	Altered Expression	[2653]
SIRT4	OT5S0J23	Strong	Biomarker	[2654]
SIRT7	OT5M4OT4	Strong	Biomarker	[2655]
SIX1	OT70YYWM	Strong	Altered Expression	[2656]
SIX2	OTYOVGSC	Strong	Biomarker	[2657]
SKI	OT4KJ8F6	Strong	Biomarker	[2658]
SLC12A9	OTR7VRAK	Strong	Biomarker	[437]
SLC22A18	OT9C3KR4	Strong	Altered Expression	[2659]
SLC2A4RG	OTW3LX8D	Strong	Biomarker	[2034]
SLC66A1	OTUM63MK	Strong	Altered Expression	[2660]
SLFN11	OTJWFPMY	Strong	Altered Expression	[2661]
SLIT1	OT35RBNT	Strong	Biomarker	[2662]
SLIT3	OTU8MKEU	Strong	Posttranslational Modification	[2663]
SMAP1	OTQN3BVL	Strong	Genetic Variation	[1718]
SMARCA1	OT0Y6PTU	Strong	Altered Expression	[2243]
SMC1A	OT9ZMRK9	Strong	Altered Expression	[2664]
SMC4	OTEJE6AG	Strong	Altered Expression	[2665]
SMR3B	OTL5HNM8	Strong	Biomarker	[856]
SMS	OT8JYKNH	Strong	Altered Expression	[1388]
SMURF1	OT5UIZR8	Strong	Biomarker	[2666]
SNAI1	OTDPYAMC	Strong	Altered Expression	[2667]
SNAI2	OT7Y8EJ2	Strong	Biomarker	[2668]
SNAI3	OTG9DI66	Strong	Biomarker	[2062]
SNAP47	OT1DE2QT	Strong	Biomarker	[341]
SNRPA1	OTWJZFAP	Strong	Altered Expression	[2669]
SNX1	OTXQSJ1J	Strong	Altered Expression	[2670]
SNX10	OT05B7BT	Strong	Biomarker	[1746]
SNX3	OTXL5W8F	Strong	Biomarker	[2671]
SOAT1	OTB4Y5RJ	Strong	Biomarker	[2672]
SOCS2	OTBPNKJQ	Strong	Biomarker	[2673]
SOCS7	OT503VJG	Strong	Biomarker	[1448]
SOX10	OTF25ULQ	Strong	Altered Expression	[2674]
SOX12	OT93P8C9	Strong	Biomarker	[357]
SOX15	OTTB37I1	Strong	Biomarker	[2675]
SOX17	OT9H4WWE	Strong	Biomarker	[2676]
SOX18	OTPUMHWA	Strong	Altered Expression	[2677]
SOX4	OTSS40SS	Strong	Biomarker	[2678]
SOX7	OTOZOFAG	Strong	Biomarker	[2679]
SOX8	OTEJXYZM	Strong	Altered Expression	[2680]
SOX9	OTVDJFGN	Strong	Biomarker	[1468]
SPART	OTIVOS2I	Strong	Biomarker	[2681]
SPDYA	OTYKC1AJ	Strong	Altered Expression	[2682]
SPEN	OT37A2MD	Strong	Biomarker	[1239]
SPIDR	OTO1OII0	Strong	Biomarker	[1859]
SPIN3	OT5PTQSH	Strong	Genetic Variation	[2683]
SPINK1	OTSUVAL2	Strong	Genetic Variation	[849]
SPNS2	OTPODAPU	Strong	Altered Expression	[2684]
SPON2	OTE7JLNM	Strong	Biomarker	[2685]
SPOP	OTP0107S	Strong	Biomarker	[1322]
SPP2	OTX254AR	Strong	Altered Expression	[2686]
SPRY2	OTH0CRCZ	Strong	Altered Expression	[961]
SPRY4	OT2VK9N0	Strong	Altered Expression	[2687]
SPSB2	OT7ZVT8R	Strong	Genetic Variation	[471]
SPTA1	OT1YMP65	Strong	Biomarker	[2688]
SPZ1	OTQH8HJ5	Strong	Altered Expression	[1914]
SRI	OT4R3EAC	Strong	Biomarker	[2689]
SRL	OT7IEBWZ	Strong	Biomarker	[2690]
SRPX2	OT6A63TX	Strong	Altered Expression	[2691]
SRRM2	OTSIMMC9	Strong	Biomarker	[852]
SRSF1	OTF61HOV	Strong	Biomarker	[2692]
SRSF10	OTY6IJ11	Strong	Altered Expression	[2693]
SRSF3	OTOFT707	Strong	Biomarker	[262]
SRSF6	OTGLOSYE	Strong	Altered Expression	[324]
SRY	OT516T6D	Strong	Altered Expression	[2674]
SSBP1	OTH2PZWH	Strong	Biomarker	[2694]
SSH1	OT4BE2M4	Strong	Altered Expression	[2695]
SSH2	OT8NCK82	Strong	Biomarker	[2696]
SSH3	OT83V0ZK	Strong	Biomarker	[2697]
SSX2	OT2Z6RLL	Strong	Biomarker	[2698]
ST13	OTNML6UP	Strong	Altered Expression	[2699]
ST6GAL1	OT7US3NO	Strong	Altered Expression	[2700]
ST6GALNAC1	OT3JQD99	Strong	Biomarker	[2701]
ST6GALNAC2	OT9PBQVT	Strong	Biomarker	[2702]
ST8SIA1	OTGND2YZ	Strong	Altered Expression	[2703]
STAG1	OT564IX4	Strong	Biomarker	[2704]
STAG2	OTR6X1Q7	Strong	Altered Expression	[2705]
STARD13	OTB4U1HY	Strong	Biomarker	[2706]
STAT2	OTO9G2RZ	Strong	Biomarker	[2707]
STAT4	OTAK3VFR	Strong	Biomarker	[2708]
STAT5A	OTBSJGN3	Strong	Biomarker	[667]
STAT5B	OTZVPEBT	Strong	Biomarker	[667]
STATH	OTQHBHM9	Strong	Genetic Variation	[2709]
STAU1	OTTR5311	Strong	Biomarker	[2710]
STEAP4	OTFTLAEZ	Strong	Biomarker	[2711]
STIM1	OT8CLQ1W	Strong	Altered Expression	[2712]
STING1	OTDAP4G0	Strong	Biomarker	[2585]
STIP1	OT7TXLOX	Strong	Biomarker	[2713]
STK11	OT1YZSP3	Strong	Biomarker	[2714]
STK24	OTGUHOIL	Strong	Biomarker	[2715]
STK25	OT4YPNTF	Strong	Biomarker	[2716]
STK31	OT3ZLRH0	Strong	Altered Expression	[2717]
STK35	OTLEMU48	Strong	Biomarker	[2718]
STOM	OTC8R6EH	Strong	Altered Expression	[975]
STRN	OTLOZL5I	Strong	Biomarker	[235]
STUB1	OTSUYI9A	Strong	Biomarker	[2719]
STX1A	OTSBUZB4	Strong	Biomarker	[2720]
STX2	OTO2IDDR	Strong	Biomarker	[2721]
SUB1	OTK71JYU	Strong	Biomarker	[1854]
SULF1	OTJCNCO0	Strong	Altered Expression	[2722]
SUMF2	OT37I8JL	Strong	Biomarker	[2723]
SUPT4H1	OTB3UCTB	Strong	Altered Expression	[2724]
SUZ12	OT655XF8	Strong	Altered Expression	[2725]
SYMPK	OTYAUDXV	Strong	Genetic Variation	[2120]
SYNE1	OTSBSLUH	Strong	Genetic Variation	[2726]
SYNJ2	OTLRHXP1	Strong	Genetic Variation	[2727]
SYP	OTFJKMO4	Strong	Altered Expression	[2728]
SYT1	OTVTPOI6	Strong	Biomarker	[755]
SYT7	OTBWAOWY	Strong	Altered Expression	[2729]
SYTL2	OTUIOWKL	Strong	Biomarker	[975]
TAB3	OT1ECMDL	Strong	Biomarker	[2730]
TAC1	OTM842YW	Strong	Biomarker	[967]
TAF1	OTDYS5G4	Strong	Genetic Variation	[2731]
TAF1C	OTNV4CDH	Strong	Genetic Variation	[2732]
TAF1L	OT9Z7EVA	Strong	Genetic Variation	[2731]
TANC1	OTF6TZ8E	Strong	Genetic Variation	[215]
TANK	OTZSGFIK	Strong	Biomarker	[2733]
TAP2	OTWSYFI7	Strong	Biomarker	[2734]
TAPBP	OTL81AVZ	Strong	Biomarker	[2735]
TAS2R16	OT67HLNS	Strong	Genetic Variation	[2736]
TBPL1	OT4I143E	Strong	Biomarker	[979]
TBX1	OTQLBPRA	Strong	Biomarker	[2737]
TBX2	OTTOT7A9	Strong	Biomarker	[2738]
TBX3	OTM64N7K	Strong	Genetic Variation	[2739]
TBX4	OTW58FG4	Strong	Altered Expression	[1388]
TBX5	OT70PISV	Strong	Biomarker	[2740]
TCEAL1	OTAPG2L5	Strong	Altered Expression	[2399]
TCERG1L	OTSBSCLF	Strong	Biomarker	[2039]
TCF12	OTZVONNU	Strong	Biomarker	[2741]
TCF4	OTB9ASTK	Strong	Altered Expression	[2742]
TCF7	OT1ID822	Strong	Genetic Variation	[2743]
TCHP	OTVDMHSY	Strong	Biomarker	[2744]
TCIM	OTARUXQF	Strong	Biomarker	[926]
TCN2	OT41D0L3	Strong	Genetic Variation	[2745]
TCP1	OT1MGUX9	Strong	Biomarker	[1232]
TCTN1	OTG5KEV8	Strong	Altered Expression	[2746]
TEAD1	OTK6971C	Strong	Biomarker	[2747]
TENM1	OTSKSU4V	Strong	Biomarker	[1464]
TENM2	OTPLUYEF	Strong	Biomarker	[1464]
TENM4	OT91K3FC	Strong	Altered Expression	[2748]
TET1	OTZDHT1D	Strong	Altered Expression	[2749]
TFAM	OTXXV5V7	Strong	Altered Expression	[2750]
TFAP2C	OTUDIW05	Strong	Altered Expression	[2751]
TFAP2E	OTA4B1SG	Strong	Biomarker	[2752]
TFCP2	OTA246TE	Strong	Biomarker	[2753]
TFEB	OTJUJJQY	Strong	Genetic Variation	[1287]
TFF2	OTRXB19X	Strong	Biomarker	[933]
TFPI2	OTZCRWOR	Strong	Altered Expression	[2749]
TGFB1I1	OTIK337D	Strong	Biomarker	[2754]
THEM6	OT51SVLH	Strong	Altered Expression	[2755]
THOC1	OTVABJ4Z	Strong	Altered Expression	[2756]
TIA1	OTGPN3P8	Strong	Biomarker	[2757]
TIMD4	OTGGC20G	Strong	Altered Expression	[2758]
TIMM44	OTXP7MXN	Strong	Altered Expression	[2759]
TIMP3	OTDGQAD1	Strong	Genetic Variation	[2760]
TINAGL1	OTZZO56M	Strong	Altered Expression	[350]
TJP2	OTQUY6BV	Strong	Biomarker	[2761]
TLE1	OT50MRZ1	Strong	Biomarker	[2762]
TLE4	OT4QEH6T	Strong	Biomarker	[2763]
TLE5	OTEH0BFG	Strong	Biomarker	[2762]
TM4SF1	OTY0ECQN	Strong	Altered Expression	[2764]
TM4SF4	OTRI8EHN	Strong	Biomarker	[2765]
TM4SF5	OTPAV531	Strong	Altered Expression	[2766]
TM9SF2	OTA0C202	Strong	Biomarker	[2767]
TMBIM1	OTE47B57	Strong	Altered Expression	[2768]
TMED6	OTLYX1ZZ	Strong	Altered Expression	[1901]
TMEFF2	OT1WZ2QO	Strong	Biomarker	[2769]
TMEM176A	OTOZDWXX	Strong	Posttranslational Modification	[2770]
TMEM208	OTMGH9OA	Strong	Altered Expression	[2660]
TMEM25	OTIMMWZ6	Strong	Posttranslational Modification	[2771]
TMEM258	OTXSDU14	Strong	Genetic Variation	[294]
TMEM9	OTXC0JXR	Strong	Biomarker	[2772]
TMPRSS13	OTMAOAP3	Strong	Biomarker	[321]
TMPRSS4	OTCCGY2K	Strong	Biomarker	[2773]
TMTC1	OTZ7NW96	Strong	Genetic Variation	[989]
TNFAIP8	OT1G9297	Strong	Biomarker	[2774]
TNFRSF19	OTTVT4MB	Strong	Biomarker	[2775]
TNFRSF6B	OTKAN9G7	Strong	Biomarker	[992]
TNS1	OTZ8S1PL	Strong	Altered Expression	[2776]
TNS3	OTPG2D8Z	Strong	Genetic Variation	[1287]
TOMM20	OT76TPR2	Strong	Biomarker	[2777]
TOMM34	OTH6MITE	Strong	Biomarker	[2778]
TOPBP1	OT6UPZPD	Strong	Genetic Variation	[2779]
TOX2	OT7RZRVK	Strong	Genetic Variation	[215]
TP53I3	OTSCM68G	Strong	Altered Expression	[2336]
TP53RK	OTARRZAB	Strong	Biomarker	[372]
TP73	OT0LUO47	Strong	Genetic Variation	[2780]
TPD52	OTPKSK43	Strong	Genetic Variation	[2287]
TPM2	OTA1L0P8	Strong	Altered Expression	[2781]
TPM3	OT5RU5G6	Strong	Biomarker	[2782]
TPPP3	OTU8VUIG	Strong	Biomarker	[2783]
TPST1	OTDPQKEA	Strong	Genetic Variation	[2784]
TRAF5	OTSBTLO0	Strong	Biomarker	[2785]
TRAM1	OT3I0H8E	Strong	Biomarker	[2786]
TRAP1	OTNG0L8J	Strong	Altered Expression	[1623]
TRAPPC4	OT3THRCA	Strong	Biomarker	[2787]
TRAPPC9	OTF0CVMC	Strong	Biomarker	[2788]
TRDMT1	OTAYQ8ZF	Strong	Biomarker	[421]
TREX2	OT5QAGJ4	Strong	Genetic Variation	[2789]
TRIB1	OTPEO17G	Strong	Altered Expression	[2790]
TRIB2	OTHSX3MX	Strong	Altered Expression	[2791]
TRIB3	OTG5OS7X	Strong	Altered Expression	[2792]
TRIM13	OTQIUACB	Strong	Altered Expression	[2793]
TRIM2	OT0V1YVC	Strong	Altered Expression	[2794]
TRIM29	OT2DNESG	Strong	Altered Expression	[2795]
TRIM3	OT704FQ0	Strong	Biomarker	[1029]
TRIM44	OT0B1T2B	Strong	Altered Expression	[2796]
TRIM52	OTKTKCT1	Strong	Biomarker	[2797]
TRIM58	OT7OIIRH	Strong	Biomarker	[2798]
TRIM65	OTSQTK3A	Strong	Altered Expression	[285]
TRIM66	OT0VJCP6	Strong	Biomarker	[2799]
TRIM67	OTXRZN27	Strong	Biomarker	[2800]
TRIM68	OTHMDMOG	Strong	Biomarker	[2801]
TRIM72	OTFAFXPC	Strong	Biomarker	[2802]
TRIM8	OTS6JFR0	Strong	Biomarker	[2803]
TRIO	OT71X1AK	Strong	Biomarker	[1937]
TRIOBP	OTGB5WHC	Strong	Biomarker	[2804]
TRIP13	OTFM3TI9	Strong	Biomarker	[2805]
TRIP6	OTIPA4ZR	Strong	Biomarker	[709]
TRMT10C	OT1L8Q48	Strong	Altered Expression	[2070]
TROAP	OTC8CE0R	Strong	Altered Expression	[2806]
TSC1	OTFF4YZ7	Strong	Biomarker	[830]
TSC22D1	OTN4GFWD	Strong	Altered Expression	[2807]
TSC22D2	OTFXF349	Strong	Altered Expression	[2808]
TSHZ1	OTYQ9ECW	Strong	Genetic Variation	[989]
TSKU	OT1XMRIM	Strong	Altered Expression	[2809]
TSPAN1	OTZQPIYK	Strong	Altered Expression	[2810]
TSPAN12	OTF9I3CX	Strong	Biomarker	[2811]
TSPYL5	OT7QEI2X	Strong	Biomarker	[2812]
TTC22	OTFNNLI1	Strong	Genetic Variation	[215]
TTC28	OTFOOYC3	Strong	Biomarker	[2813]
TTLL3	OT7JWXHA	Strong	Altered Expression	[2814]
ABCA13	OTTHTUQN	Definitive	Biomarker	[1068]
ABCE1	OTH19LOA	Definitive	Biomarker	[1068]
ADAM15	OTZ7VLTP	Definitive	Altered Expression	[2815]
ANGPTL6	OTOQ5W67	Definitive	Biomarker	[2816]
ARMCX1	OTOGL58Z	Definitive	Altered Expression	[2817]
ARMH1	OTTJC0D6	Definitive	Biomarker	[1085]
ATG10	OTVRPC5X	Definitive	Biomarker	[2818]
ATP2A3	OTFYDEES	Definitive	Altered Expression	[2819]
ATP5F1C	OTV5GZK5	Definitive	Genetic Variation	[2820]
CADM1	OTRWG9QS	Definitive	Biomarker	[2821]
CALCOCO2	OTRGX0OV	Definitive	Biomarker	[1083]
CALD1	OTNJKJ6Q	Definitive	Altered Expression	[2822]
CBX5	OT8VYY84	Definitive	Biomarker	[1083]
CD81	OTQFXNAZ	Definitive	Biomarker	[2823]
CDH22	OTQEUWQN	Definitive	Biomarker	[1083]
CDK5RAP3	OTC0Q2QS	Definitive	Genetic Variation	[2824]
CLPTM1L	OTDJWQXI	Definitive	Genetic Variation	[2825]
CMPK2	OTOG90R0	Definitive	Biomarker	[1150]
CMTM2	OTSJISGF	Definitive	Biomarker	[1988]
CNPPD1	OT8G88R2	Definitive	Biomarker	[1083]
COPS6	OTG9AAG0	Definitive	Altered Expression	[2826]
CTPS2	OT2X9YO1	Definitive	Altered Expression	[2827]
CYBRD1	OTUTVBES	Definitive	Genetic Variation	[2828]
DESI2	OTHUOKOC	Definitive	Altered Expression	[2829]
DIDO1	OT9PB547	Definitive	Biomarker	[2830]
DONSON	OTN5HE0W	Definitive	Biomarker	[1083]
DPAGT1	OTYEJAGZ	Definitive	Biomarker	[1083]
DSC1	OTNII6GZ	Definitive	Biomarker	[2831]
EBNA1BP2	OTBRVMZH	Definitive	Biomarker	[1085]
ECM1	OT1K65VW	Definitive	Biomarker	[2832]
ELF3	OTUTLEQO	Definitive	Altered Expression	[2833]
ELK1	OTH9MXD6	Definitive	Biomarker	[2834]
EPS8	OTZ6ES6V	Definitive	Altered Expression	[2835]
ETV1	OT6PMJIK	Definitive	Biomarker	[2836]
FGF12	OTBM9QIO	Definitive	Biomarker	[1080]
FXYD1	OTNKT6GP	Definitive	Biomarker	[2837]
GLYR1	OTY0VAVL	Definitive	Genetic Variation	[2838]
GNB5	OT3ZSAXH	Definitive	Biomarker	[1083]
GPR162	OTK4LT3K	Definitive	Biomarker	[2839]
GRID1	OTJ3WIKC	Definitive	Biomarker	[1484]
HLA-DRA	OT7KZMP2	Definitive	Altered Expression	[2840]
HLTF	OTRX2OSF	Definitive	Genetic Variation	[2841]
HOXD9	OTZ4GVR1	Definitive	Biomarker	[2842]
ICAM5	OTDGGAFH	Definitive	Biomarker	[1484]
INA	OT1D33T4	Definitive	Biomarker	[2843]
IPP	OTCGBS3H	Definitive	Biomarker	[1083]
LAMA2	OTFROQWE	Definitive	Posttranslational Modification	[1079]
LGALS3BP	OT9AGQKH	Definitive	Biomarker	[2844]
LRRC28	OTFTT6VN	Definitive	Altered Expression	[2845]
LRRFIP1	OTN7XAUD	Definitive	Biomarker	[2846]
MED12	OTQZ4D2X	Definitive	Biomarker	[2847]
MEF2C	OTZGF1Y5	Definitive	Biomarker	[2837]
MPP3	OTNOL0HA	Definitive	Posttranslational Modification	[2848]
MSN	OTZJ4J6G	Definitive	Altered Expression	[2849]
MT1X	OT9AKFVS	Definitive	Biomarker	[2850]
MYCBP2	OTHODA1F	Definitive	Biomarker	[2851]
MYO1A	OTS80FOD	Definitive	Biomarker	[2852]
NAV3	OT97M1TR	Definitive	Genetic Variation	[2853]
NME3	OT0CA0GF	Definitive	Biomarker	[2854]
NSUN2	OTZCNM33	Definitive	Biomarker	[2855]
NUP210	OT3BLQ9M	Definitive	Genetic Variation	[2134]
OGA	OT7ZBWT1	Definitive	Altered Expression	[2856]
PABPC4	OTICKKBQ	Definitive	Biomarker	[2857]
PAIP2	OTFNVLSK	Definitive	Biomarker	[1083]
PAQR3	OTTKJ9Y4	Definitive	Altered Expression	[2858]
PAX8	OTRPD9MI	Definitive	Biomarker	[2842]
PEBP4	OTKDCVC6	Definitive	Altered Expression	[2859]
PHACTR3	OTUN0OAY	Definitive	Posttranslational Modification	[2860]
PHETA1	OT4IMC0X	Definitive	Biomarker	[1083]
PLSCR1	OTGY9B5T	Definitive	Altered Expression	[2861]
PPM1E	OTXRH3YA	Definitive	Biomarker	[1484]
PSD	OTUZIXUZ	Definitive	Genetic Variation	[2862]
PSMD7	OT7PZZ4K	Definitive	Biomarker	[1085]
RABEPK	OTCZSREH	Definitive	Biomarker	[1085]
RAD51D	OTKOU5XN	Definitive	Genetic Variation	[2863]
RAP1B	OTHEIIMM	Definitive	Biomarker	[2864]
RASL11A	OTDO6CMY	Definitive	Biomarker	[2836]
RBM39	OTCMPTF9	Definitive	Biomarker	[2830]
RIF1	OTPE49OE	Definitive	Genetic Variation	[2779]
SAP130	OT01SO0E	Definitive	Altered Expression	[2865]
SART1	OTHMOGO1	Definitive	Biomarker	[2866]
SCARA5	OTOVA96E	Definitive	Biomarker	[2867]
SELENOF	OT2JFB3S	Definitive	Biomarker	[1090]
SELENOH	OTZ0QU22	Definitive	Biomarker	[1090]
SFXN1	OTL66767	Definitive	Biomarker	[1083]
SH3GL3	OTX6BOCN	Definitive	Biomarker	[1988]
SLC22A15	OT60WAAI	Definitive	Biomarker	[1484]
SLURP1	OT89YD2E	Definitive	Genetic Variation	[2868]
SMARCB1	OT2LP7LJ	Definitive	Biomarker	[2869]
SPAG9	OT45AHMB	Definitive	Biomarker	[2870]
SPIC	OTUOMSRP	Definitive	Biomarker	[2871]
STARD8	OTY9IAKW	Definitive	Biomarker	[1484]
STEAP3	OTS9GZK5	Definitive	Altered Expression	[2872]
STIM2	OTYNXAW0	Definitive	Altered Expression	[2873]
THSD1	OTKPGFHS	Definitive	Biomarker	[2874]

References

• [1] Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study. Lancet Oncol. 2015 May;16(5):499-508.
• [2] Doxycycline FDA Label
• [3] Folic acid FDA Label
• [4] Levoleucovorin FDA Label
• [5] Metformin FDA Label
• [6] Oxaliplatin FDA Label
• [7] High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.PLoS One. 2015 Mar 20;10(3):e0119255. doi: 10.1371/journal.pone.0119255. eCollection 2015.
• [8] Reduced capacity for DNA repair synthesis in patients with or genetically predisposed to colorectal cancer.J Natl Cancer Inst. 1983 May;70(5):867-75.
• [9] Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer.Anticancer Res. 2009 Mar;29(3):851-7.
• [10] Adenosine kinase gene expression in human colorectal cancer.Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):750-4. doi: 10.1080/15257770802145629.
• [11] Adrenomedullin is a therapeutic target in colorectal cancer.Int J Cancer. 2014 May 1;134(9):2041-50. doi: 10.1002/ijc.28542. Epub 2013 Nov 7.
• [12] Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers.Br J Cancer. 2007 Jan 29;96(2):383-90. doi: 10.1038/sj.bjc.6603555.
• [13] Association of polymorphisms in the beta-2 and beta-3 adrenoceptor genes with risk of colorectal cancer in Japanese.Int J Clin Oncol. 2001 Jun;6(3):117-22. doi: 10.1007/pl00012092.
• [14] Clinicopathological features and prognosis of AFP-producing colorectal cancer: a single-center analysis of 20 cases.Cancer Manag Res. 2019 May 16;11:4557-4567. doi: 10.2147/CMAR.S196919. eCollection 2019.
• [15] Novel RNA variants in colorectal cancers.Oncotarget. 2015 Nov 3;6(34):36587-602. doi: 10.18632/oncotarget.5500.
• [16] Correlation analysis of IL-4, IL-10 and APN levels with postoperative infection of colorectal cancer.Oncol Lett. 2019 Feb;17(2):1603-1608. doi: 10.3892/ol.2018.9798. Epub 2018 Dec 6.
• [17] Exploiting DNA repair defects in colorectal cancer.Mol Oncol. 2019 Apr;13(4):681-700. doi: 10.1002/1878-0261.12467. Epub 2019 Mar 2.
• [18] Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells.J Pathol. 2011 Oct;225(2):243-54. doi: 10.1002/path.2934. Epub 2011 Jun 27.
• [19] The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.Cell Death Dis. 2018 Jan 26;9(2):125. doi: 10.1038/s41419-017-0140-2.
• [20] Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer.Mol Cancer. 2015 Jul 2;14:126. doi: 10.1186/s12943-015-0397-y.
• [21] Pleiotropic Effects of PPARD Accelerate Colorectal Tumorigenesis, Progression, and Invasion.Cancer Res. 2019 Mar 1;79(5):954-969. doi: 10.1158/0008-5472.CAN-18-1790. Epub 2019 Jan 24.
• [22] Expression of tumor related genes NGX6, NAG-7, BRD7 in gastric and colorectal cancer.World J Gastroenterol. 2003 Aug;9(8):1729-33. doi: 10.3748/wjg.v9.i8.1729.
• [23] BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.J Pathol. 2020 Feb;250(2):134-147. doi: 10.1002/path.5347. Epub 2019 Dec 2.
• [24] BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability.Int J Colorectal Dis. 2004 Nov;19(6):538-44. doi: 10.1007/s00384-004-0597-1. Epub 2004 Apr 14.
• [25] miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.Transl Oncol. 2019 Feb;12(2):282-291. doi: 10.1016/j.tranon.2018.10.013. Epub 2018 Nov 16.
• [26] miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer.Sci Rep. 2019 Apr 1;9(1):5405. doi: 10.1038/s41598-019-41862-2.
• [27] Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression via CCR5.Cell Death Dis. 2019 Mar 19;10(4):264. doi: 10.1038/s41419-019-1508-2.
• [28] CCR7 high expression leads to cetuximab resistance by cross-talking with EGFR pathway in PI3K/AKT signals in colorectal cancer.Am J Cancer Res. 2019 Nov 1;9(11):2531-2543. eCollection 2019.
• [29] CD70 expression in tumor-associated fibroblasts predicts worse survival in colorectal cancer patients.Virchows Arch. 2019 Oct;475(4):425-434. doi: 10.1007/s00428-019-02565-1. Epub 2019 Apr 13.
• [30] Non-invasive detection of c-myc p64, c-myc p67 and c-erbb-2 in colorectal cancer.Scand J Gastroenterol. 2005 Nov;40(11):1343-50. doi: 10.1080/00365520510023549.
• [31] Membrane-bound complement regulatory proteins inhibit complement activation by an immunotherapeutic mAb in a syngeneic rat colorectal cancer model.Mol Immunol. 2003 Sep;40(1):13-23. doi: 10.1016/s0161-5890(03)00048-8.
• [32] The microbiome of pancreatic cancer: from molecular diagnostics to new therapeutic approaches to overcome chemoresistance caused by metabolic inactivation of gemcitabine.Expert Rev Mol Diagn. 2018 Dec;18(12):1005-1009. doi: 10.1080/14737159.2018.1544495. Epub 2018 Nov 9.
• [33] Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer.Sci Adv. 2019 Sep 18;5(9):eaax2277. doi: 10.1126/sciadv.aax2277. eCollection 2019 Sep.
• [34] Downregulation of lncRNA NR2F2 Antisense RNA 1 Induces G1 Arrest of Colorectal Cancer Cells by Downregulating Cyclin-Dependent Kinase 6.Dig Dis Sci. 2020 Feb;65(2):464-469. doi: 10.1007/s10620-019-05782-5. Epub 2019 Aug 20.
• [35] Antitumor effects of a covalent cyclin-dependent kinase 7 inhibitor in colorectal cancer.Anticancer Drugs. 2019 Jun;30(5):466-474. doi: 10.1097/CAD.0000000000000749.
• [36] WITHDRAWN: LncRNA DSCAM-AS1 Promotes Proliferation, Migration and Invasion of Colorectal Cancer Cells via Modulating miR-144-5p/CDKL1.Life Sci. 2019 Nov 12:117050. doi: 10.1016/j.lfs.2019.117050. Online ahead of print.
• [37] Recombinant Salmonella-based CEACAM6 and 4-1BBL vaccine enhances T-cell immunity and inhibits the development of colorectal cancer in rats: In vivo effects of vaccine containing 4-1BBL and CEACAM6.Oncol Rep. 2015 Jun;33(6):2837-44. doi: 10.3892/or.2015.3901. Epub 2015 Apr 7.
• [38] C/EBP Promotion of MMP3-Dependent Tumor Cell Invasion and Association with Metastasis in Colorectal Cancer.Genet Test Mol Biomarkers. 2018 Jan;22(1):5-10. doi: 10.1089/gtmb.2017.0113. Epub 2017 Nov 27.
• [39] MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling.Cell Death Dis. 2019 Aug 13;10(8):615. doi: 10.1038/s41419-019-1844-2.
• [40] The expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates differently dependent on tumor location.Neoplasma. 2018 Nov 15;65(6):986-992. doi: 10.4149/neo_2018_180122N47. Epub 2018 Jun 18.
• [41] Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population.Sci Rep. 2018 Aug 6;8(1):11731. doi: 10.1038/s41598-018-29589-y.
• [42] Expression of circadian clock genes in human colorectal adenoma and carcinoma.Oncol Lett. 2017 Nov;14(5):5319-5325. doi: 10.3892/ol.2017.6876. Epub 2017 Sep 4.
• [43] Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility.Carcinogenesis. 2010 Sep;31(9):1612-9. doi: 10.1093/carcin/bgq146. Epub 2010 Jul 7.
• [44] Expression and immunogenicity of NY-ESO-1 in colorectal cancer.Exp Ther Med. 2017 Jun;13(6):3581-3585. doi: 10.3892/etm.2017.4405. Epub 2017 Apr 28.
• [45] Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer.Cell Death Differ. 2019 Nov;26(11):2447-2463. doi: 10.1038/s41418-019-0312-y. Epub 2019 Mar 8.
• [46] The prognostic value of CXC subfamily ligands in stage I-III patients with colorectal cancer.PLoS One. 2019 Apr 11;14(4):e0214611. doi: 10.1371/journal.pone.0214611. eCollection 2019.
• [47] CXCR4/TGF-1 mediated self-differentiation of human mesenchymal stem cells to carcinoma-associated fibroblasts and promoted colorectal carcinoma development.Cancer Biol Ther. 2020;21(3):248-257. doi: 10.1080/15384047.2019.1685156. Epub 2019 Dec 10.
• [48] Prediction of Early Recurrence After Curative Resection of Colorectal Liver Metastasis and Subsequent S-1 Chemotherapy.Anticancer Res. 2016 May;36(5):2175-9.
• [49] Tumor response to irinotecan is associated with CYP3A5 expression in colorectal cancer.Oncol Lett. 2019 Apr;17(4):3890-3898. doi: 10.3892/ol.2019.10043. Epub 2019 Feb 14.
• [50] Genetic Analysis Using a Gene Panel in 87 Caucasian Patients With Colorectal Cancer: Own Results and Review of Literature.Anticancer Res. 2019 Feb;39(2):847-852. doi: 10.21873/anticanres.13184.
• [51] Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer.Theranostics. 2019 Jan 30;9(4):1001-1014. doi: 10.7150/thno.30056. eCollection 2019.
• [52] Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial.Int J Cancer. 2009 May 1;124(9):2148-51. doi: 10.1002/ijc.24079.
• [53] DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression.Cancers (Basel). 2019 Nov 9;11(11):1767. doi: 10.3390/cancers11111767.
• [54] Corrigendum to "Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway".Mediators Inflamm. 2017;2017:2917134. doi: 10.1155/2017/2917134. Epub 2017 Jul 27.
• [55] Increased expression of the transcription factors CCAAT-enhancer binding protein-beta (C/EBBeta) and C/EBzeta (CHOP) correlate with invasiveness of human colorectal cancer.Int J Cancer. 2000 May 1;86(3):337-43. doi: 10.1002/(sici)1097-0215(20000501)86:3<337::aid-ijc6>3.0.co;2-3.
• [56] EGFL6 promotes cell proliferation in colorectal cancer via regulation of the WNT/-catenin pathway.Mol Carcinog. 2019 Jun;58(6):967-979. doi: 10.1002/mc.22985. Epub 2019 Mar 3.
• [57] MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR).Cancer Lett. 2018 May 1;421:145-151. doi: 10.1016/j.canlet.2018.02.026. Epub 2018 Feb 20.
• [58] Association of Genetic Variants with Colorectal Cancer in the Extended MENA Region: A Systematic Review.Curr Mol Med. 2020;20(4):286-298. doi: 10.2174/1566524019666191014170136.
• [59] Immunological differences between colorectal cancer and normal mucosa uncover a prognostically relevant immune cell profile.Oncoimmunology. 2018 Nov 5;8(2):e1537693. doi: 10.1080/2162402X.2018.1537693. eCollection 2019.
• [60] Overexpression of EphA4 gene and reduced expression of EphB2 gene correlates with liver metastasis in colorectal cancer.Int J Oncol. 2008 Sep;33(3):573-7.
• [61] VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.Int J Cancer. 2020 Jan 15;146(2):496-509. doi: 10.1002/ijc.32429. Epub 2019 Jun 19.
• [62] ERR Regulates OTUB1 Expression to Promote Colorectal Cancer Cell Migration.J Cancer. 2019 Oct 6;10(23):5812-5819. doi: 10.7150/jca.30720. eCollection 2019.
• [63] microRNA-211 promotes invasion and migration of colorectal cancer cells by targeting FABP4 via PPAR.J Cell Physiol. 2019 Sep;234(9):15429-15437. doi: 10.1002/jcp.28190. Epub 2019 Feb 26.
• [64] FAM83D knockdown regulates proliferation, migration and invasion of colorectal cancer through inhibiting FBXW7/Notch-1 signalling pathway. Biomed Pharmacother. 2017 Jun;90:548-554.
• [65] Vaccination With a FAT1-Derived B Cell Epitope Combined With Tumor-Specific B and T Cell Epitopes Elicits Additive Protection in Cancer Mouse Models.Front Oncol. 2018 Oct 26;8:481. doi: 10.3389/fonc.2018.00481. eCollection 2018.
• [66] In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.Int J Cancer. 2020 Jan 1;146(1):236-247. doi: 10.1002/ijc.32663. Epub 2019 Oct 12.
• [67] Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon.Cancer Res. 2006 Jan 15;66(2):1191-8. doi: 10.1158/0008-5472.CAN-05-2926.
• [68] Gene expression of fructosamine 3 kinase in patients with colorectal cancer.Oncology. 2007;73(1-2):72-5. doi: 10.1159/000120631. Epub 2008 Mar 12.
• [69] Long Non-coding RNA ITIH4-AS1 Accelerates the Proliferation and Metastasis of Colorectal Cancer by Activating JAK/STAT3 Signaling.Mol Ther Nucleic Acids. 2019 Dec 6;18:183-193. doi: 10.1016/j.omtn.2019.08.009. Epub 2019 Aug 16.
• [70] Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues.BMC Med Genet. 2019 Aug 13;20(1):138. doi: 10.1186/s12881-019-0867-y.
• [71] KIR genes and HLA class I ligands in a Caucasian Brazilian population with colorectal cancer.Hum Immunol. 2017 Mar;78(3):263-268. doi: 10.1016/j.humimm.2017.01.003. Epub 2017 Jan 11.
• [72] Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair.Mol Med Rep. 2014 Jul;10(1):486-90. doi: 10.3892/mmr.2014.2185. Epub 2014 Apr 24.
• [73] Glucose-dependent insulinotropic polypeptide stimulates the proliferation of colorectal cancer cells.Regul Pept. 2010 Aug 9;163(1-3):74-80. doi: 10.1016/j.regpep.2010.04.005. Epub 2010 Apr 28.
• [74] Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer.Oncogene. 2020 Jan;39(1):136-150. doi: 10.1038/s41388-019-0972-6. Epub 2019 Aug 28.
• [75] Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis.Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):111-128. doi: 10.1038/nrgastro.2017.119. Epub 2017 Oct 11.
• [76] The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.Oncogene. 2008 Mar 27;27(14):2045-54. doi: 10.1038/sj.onc.1210842. Epub 2007 Oct 8.
• [77] Isolation of a novel gene showing reduced expression in metastatic colorectal carcinoma cell lines and carcinomas.Jpn J Cancer Res. 1997 Aug;88(8):725-31. doi: 10.1111/j.1349-7006.1997.tb00443.x.
• [78] BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer.Oncology. 2010;79(5-6):430-9. doi: 10.1159/000326564. Epub 2011 Apr 8.
• [79] Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. Nat Commun. 2016 Oct 5;7:13084.
• [80] Upregulation of AKAP12 with HDAC3 depletion suppresses the progression and migration of colorectal cancer.Int J Oncol. 2018 Apr;52(4):1305-1316. doi: 10.3892/ijo.2018.4284. Epub 2018 Feb 23.
• [81] B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2.Cell Death Dis. 2019 Apr 5;10(4):308. doi: 10.1038/s41419-019-1549-6.
• [82] Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer.Cell Res. 2020 Jan;30(1):34-49. doi: 10.1038/s41422-019-0259-z. Epub 2019 Dec 6.
• [83] Oestrogen and colorectal cancer: mechanisms and controversies.Int J Colorectal Dis. 2013 Jun;28(6):737-49. doi: 10.1007/s00384-012-1628-y. Epub 2013 Jan 15.
• [84] Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition.IUBMB Life. 2020 Apr;72(4):771-781. doi: 10.1002/iub.2176. Epub 2019 Oct 24.
• [85] Molecular phenotype of inflammatory bowel disease-associated neoplasms with microsatellite instability.Gastroenterology. 2005 Jul;129(1):74-85. doi: 10.1053/j.gastro.2005.04.011.
• [86] Inhibitor of DNA binding 1 (Id1) mediates stemness of colorectal cancer cells through the Id1-c-Myc-PLAC8 axis via the Wnt/-catenin and Shh signaling pathways.Cancer Manag Res. 2019 Jul 23;11:6855-6869. doi: 10.2147/CMAR.S207167. eCollection 2019.
• [87] Identifying the key genes and microRNAs in colorectal cancer liver metastasis by bioinformatics analysis and invitro experiments.Oncol Rep. 2019 Jan;41(1):279-291. doi: 10.3892/or.2018.6840. Epub 2018 Nov 1.
• [88] Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy.J Exp Clin Cancer Res. 2019 Feb 8;38(1):63. doi: 10.1186/s13046-019-1072-8.
• [89] Role of the IL-33/ST2L axis in colorectal cancer progression.Cell Immunol. 2019 Sep;343:103740. doi: 10.1016/j.cellimm.2017.12.014. Epub 2018 Jan 9.
• [90] BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt.Br J Cancer. 2014 Jul 8;111(1):101-11. doi: 10.1038/bjc.2014.227. Epub 2014 Jun 3.
• [91] Epigenome-wide association study of adiposity and future risk of obesity-related diseases.Int J Obes (Lond). 2018 Dec;42(12):2022-2035. doi: 10.1038/s41366-018-0064-7. Epub 2018 May 1.
• [92] Transcription of the inositol polyphosphate 1-phosphatase gene (INPP1) is upregulated in human colorectal cancer.Mol Carcinog. 2000 Apr;27(4):322-9. doi: 10.1002/(sici)1098-2744(200004)27:4<322::aid-mc10>3.0.co;2-c.
• [93] CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells.Oncogene. 2017 Mar;36(10):1351-1363. doi: 10.1038/onc.2016.299. Epub 2016 Sep 5.
• [94] Altered expression of KCNK9 in colorectal cancers.APMIS. 2004 Sep;112(9):588-94. doi: 10.1111/j.1600-0463.2004.apm1120905.x.
• [95] Pseudopod-associated protein KIF20B promotes Gli1-induced epithelial-mesenchymal transition modulated by pseudopodial actin dynamic in human colorectal cancer.Mol Carcinog. 2018 Jul;57(7):911-925. doi: 10.1002/mc.22812. Epub 2018 Apr 10.
• [96] Low KISS1 expression predicts poor prognosis for patients with colorectal cancer: A meta-analysis.Clin Exp Pharmacol Physiol. 2019 Jul;46(7):625-634. doi: 10.1111/1440-1681.13093. Epub 2019 Apr 25.
• [97] Health-Related Lifestyles and Cancer-Preventive Behaviors of Medical and Nursing Students and Family Medicine Residents in Relation to the European Code Against Cancer.J Cancer Educ. 2021 Jun;36(3):576-583. doi: 10.1007/s13187-019-01667-3.
• [98] Clinical significance of human kallikrein gene 6 messenger RNA expression in colorectal cancer.Clin Cancer Res. 2005 Apr 15;11(8):2889-93. doi: 10.1158/1078-0432.CCR-04-2281.
• [99] Uncovering the clinical impact of kallikrein-related peptidase 5 (KLK5) mRNA expression in the colorectal adenoma-carcinoma sequence.Clin Chem Lab Med. 2019 Jul 26;57(8):1251-1260. doi: 10.1515/cclm-2018-1010.
• [100] Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens.Eur J Cancer. 1996 Jul;32A(8):1401-7. doi: 10.1016/0959-8049(96)00090-1.
• [101] TLR4-mediated galectin-1 production triggers epithelial-mesenchymal transition in colon cancer cells through ADAM10- and ADAM17-associated lactate production.Mol Cell Biochem. 2017 Jan;425(1-2):191-202. doi: 10.1007/s11010-016-2873-0. Epub 2016 Nov 12.
• [102] Autotaxin determines colitis severity in mice and is secreted by B cells in the colon.FASEB J. 2019 Mar;33(3):3623-3635. doi: 10.1096/fj.201801415RR. Epub 2018 Nov 27.
• [103] G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.Int J Cancer. 2018 Jan 1;142(1):121-132. doi: 10.1002/ijc.31030. Epub 2017 Sep 21.
• [104] Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray.Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):415-20. doi: 10.1158/1078-0432.CCR-06-0753.
• [105] Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.J Mol Med (Berl). 2007 Mar;85(3):293-304. doi: 10.1007/s00109-006-0126-5. Epub 2006 Dec 2.
• [106] A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer.J Pathol. 2010 Mar;220(4):475-89. doi: 10.1002/path.2668.
• [107] Infrequent and low expression of cancer-testis antigens located on the X chromosome in colorectal cancer: implications for immunotherapy in South African populations.Biotechnol J. 2008 Nov;3(11):1417-23. doi: 10.1002/biot.200800144.
• [108] Long noncoding RNA MLK7AS1 promotes proliferation in human colorectal cancer via downregulation of p21 expression.Mol Med Rep. 2019 Feb;19(2):1210-1221. doi: 10.3892/mmr.2018.9702. Epub 2018 Nov 28.
• [109] TPL2 expression is correlated with distant metastasis and poor prognosis in colorectal cancer.Hum Pathol. 2018 Sep;79:50-56. doi: 10.1016/j.humpath.2018.05.003. Epub 2018 May 12.
• [110] Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2.Mol Cancer Res. 2019 Dec;17(12):2469-2479. doi: 10.1158/1541-7786.MCR-19-0553. Epub 2019 Oct 1.
• [111] Midkine is up-regulated in both cancerous and inflamed bowel, reflecting lymph node metastasis in colorectal cancer and clinical activity of ulcerative colitis.Cytokine. 2017 Jan;89:68-75. doi: 10.1016/j.cyto.2016.09.020. Epub 2016 Sep 28.
• [112] A study on the correlations of MRP-1 expression with the pathogenesis and prognosis of colorectal cancer.J BUON. 2019 Jan-Feb;24(1):84-90.
• [113] KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer.Int J Oncol. 2018 Nov;53(5):1939-1952. doi: 10.3892/ijo.2018.4546. Epub 2018 Aug 29.
• [114] High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma.Sci Rep. 2017 Apr 19;7:46531. doi: 10.1038/srep46531.
• [115] Identification of high-risk stage II and stage III colorectal cancer by analysis of MMP-21 expression.J Surg Oncol. 2011 Dec;104(7):787-91. doi: 10.1002/jso.21970. Epub 2011 Jun 7.
• [116] Suppression of intestinal tumorigenesis in Apc mutant mice upon Musashi-1 deletion.J Cell Sci. 2017 Feb 15;130(4):805-813. doi: 10.1242/jcs.197574. Epub 2017 Jan 12.
• [117] aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including BCR and ABL.Mutat Res. 2007 Feb 3;615(1-2):1-11. doi: 10.1016/j.mrfmmm.2006.09.006. Epub 2007 Jan 2.
• [118] The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer.World J Surg Oncol. 2007 Mar 9;5:31. doi: 10.1186/1477-7819-5-31.
• [119] Clinicopathological features and phenotypic classification of de novo-type colorectal carcinomas differ from those of colorectal carcinomas derived from flat adenomas.Pathol Int. 2019 Jun;69(6):331-340. doi: 10.1111/pin.12803. Epub 2019 Jul 7.
• [120] Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer.Mol Cancer. 2019 Mar 19;18(1):43. doi: 10.1186/s12943-019-0981-7.
• [121] Mutational analysis of the kinase domain of MYLK2 gene in common human cancers.Pathol Res Pract. 2006;202(3):137-40. doi: 10.1016/j.prp.2005.12.003. Epub 2006 Jan 31.
• [122] Circulating CD16+CD56+ nature killer cells indicate the prognosis of colorectal cancer after initial chemotherapy.Med Oncol. 2019 Sep 6;36(10):84. doi: 10.1007/s12032-019-1307-8.
• [123] Gender-specific association of NFKBIA promoter polymorphisms with the risk of sporadic colorectal cancer.Med Oncol. 2013 Dec;30(4):693. doi: 10.1007/s12032-013-0693-6. Epub 2013 Aug 31.
• [124] Apelin13/APJ promotes proliferation of colon carcinoma by activating Notch3 signaling pathway.Oncotarget. 2017 Oct 13;8(60):101697-101706. doi: 10.18632/oncotarget.21904. eCollection 2017 Nov 24.
• [125] Genetic alterations and expression of the protein phosphatase 1 genes in human cancers.Int J Oncol. 2001 Apr;18(4):817-24. doi: 10.3892/ijo.18.4.817.
• [126] MiR-506 Suppresses Colorectal Cancer Development by Inhibiting Orphan Nuclear Receptor NR4A1 Expression.J Cancer. 2019 Jun 9;10(15):3560-3570. doi: 10.7150/jca.28272. eCollection 2019.
• [127] Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy.Eur J Cancer. 2013 Nov;49(16):3420-30. doi: 10.1016/j.ejca.2013.06.001. Epub 2013 Jun 25.
• [128] N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals.Nat Commun. 2019 Aug 16;10(1):3708. doi: 10.1038/s41467-019-11580-4.
• [129] Expression and clinical significance of serum NT5E protein in patients with colorectal cancer.Cancer Biomark. 2019;24(4):461-468. doi: 10.3233/CBM-182207.
• [130] Genetic instability on chromosome 17 in the epithelium of non-polypoid colorectal carcinomas compared to polypoid lesions.Cancer Sci. 2006 Dec;97(12):1335-42. doi: 10.1111/j.1349-7006.2006.00334.x. Epub 2006 Oct 9.
• [131] The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca(2+) homeostasis.Oncogene. 2017 Jun 22;36(25):3640-3647. doi: 10.1038/onc.2016.501. Epub 2017 Jan 23.
• [132] SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma.Arch Pathol Lab Med. 2017 Apr;141(4):564-568. doi: 10.5858/arpa.2016-0147-OA. Epub 2017 Feb 28.
• [133] PB-10, a thiazolo[4,5-d] pyrimidine derivative, targets p21-activated kinase 4 in human colorectal cancer cells.Bioorg Med Chem Lett. 2020 Jan 15;30(2):126807. doi: 10.1016/j.bmcl.2019.126807. Epub 2019 Nov 9.
• [134] Novel selective TOPK inhibitor SKLB-C05 inhibits colorectal carcinoma growth and metastasis.Cancer Lett. 2019 Mar 31;445:11-23. doi: 10.1016/j.canlet.2018.12.016. Epub 2018 Dec 24.
• [135] Combined prognostic value of CD274 (PD-L1)/PDCDI (PD-1) expression and immune cell infiltration in colorectal cancer as per mismatch repair status.Mod Pathol. 2019 Jun;32(6):866-883. doi: 10.1038/s41379-019-0219-7. Epub 2019 Feb 5.
• [136] Inhibition of phosphodiesterase 4D decreases the malignant properties of DLD-1 colorectal cancer cells by repressing the AKT/mTOR/Myc signaling pathway.Oncol Lett. 2019 Mar;17(3):3589-3598. doi: 10.3892/ol.2019.9996. Epub 2019 Jan 31.
• [137] Phosphodiesterase 4B is an effective therapeutic target in colorectal cancer.Biochem Biophys Res Commun. 2019 Jan 15;508(3):825-831. doi: 10.1016/j.bbrc.2018.12.004. Epub 2018 Dec 7.
• [138] Targeting the paracrine hormone-dependent guanylate cyclase/cGMP/phosphodiesterases signaling pathway for colorectal cancer prevention.Semin Cancer Biol. 2019 Jun;56:168-174. doi: 10.1016/j.semcancer.2018.08.011. Epub 2018 Sep 3.
• [139] Transcription factor PDX-1 in human colorectal adenocarcinoma: a potential tumor marker?.World J Gastroenterol. 2008 Oct 14;14(38):5823-6. doi: 10.3748/wjg.14.5823.
• [140] Non-platelet-derived CXCL4 differentially regulates cytotoxic and regulatory T cells through CXCR3 to suppress the immune response to colon cancer.Cancer Lett. 2019 Feb 28;443:1-12. doi: 10.1016/j.canlet.2018.11.017. Epub 2018 Nov 24.
• [141] Selective suicide gene therapy of colon cancer exploiting the urokinase plasminogen activator receptor promoter.BioDrugs. 2010 Apr 1;24(2):131-46. doi: 10.2165/11530840-000000000-00000.
• [142] High PLK4 expression promotes tumor progression and induces epithelialmesenchymal transition by regulating the Wnt/catenin signaling pathway in colorectal cancer.Int J Oncol. 2019 Feb;54(2):479-490. doi: 10.3892/ijo.2018.4659. Epub 2018 Dec 10.
• [143] Tumor-induced DNA methylation in the white blood cells of patients with colorectal cancer.Oncol Lett. 2019 Sep;18(3):3039-3048. doi: 10.3892/ol.2019.10638. Epub 2019 Jul 18.
• [144] DNA polymerase as a novel target for chemotherapeutic intervention of colorectal cancer.PLoS One. 2011 Feb 2;6(2):e16691. doi: 10.1371/journal.pone.0016691.
• [145] Nonylphenol promotes the proliferation of colorectal cancer COLO205 cells by upregulating the expression of protein kinase C .Oncol Lett. 2019 Feb;17(2):2498-2506. doi: 10.3892/ol.2018.9846. Epub 2018 Dec 18.
• [146] NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression.Cell Death Dis. 2019 Mar 11;10(3):236. doi: 10.1038/s41419-019-1487-3.
• [147] Expression pattern of breast-cancer-associated protein pS2/BCEI in colorectal tumors.Int J Cancer. 1994 Jan 2;56(1):52-5. doi: 10.1002/ijc.2910560110.
• [148] Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma.Mol Oncol. 2015 Aug;9(7):1252-8. doi: 10.1016/j.molonc.2015.01.009. Epub 2015 Mar 5.
• [149] Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients.Virchows Arch. 2009 Jun;454(6):667-76. doi: 10.1007/s00428-009-0777-z. Epub 2009 May 2.
• [150] Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy.Oncogene. 2005 Nov 10;24(49):7320-6. doi: 10.1038/sj.onc.1208883.
• [151] The PTPN13 Y2081D (T>G) (rs989902) polymorphism is associated with an increased risk of sporadic colorectal cancer.Colorectal Dis. 2017 Jul;19(7):O272-O278. doi: 10.1111/codi.13727.
• [152] Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells.Sci Rep. 2017 Sep 29;7(1):12406. doi: 10.1038/s41598-017-12795-5.
• [153] RACK1 Acts as a Potential Tumor Promoter in Colorectal Cancer.Gastroenterol Res Pract. 2019 Mar 10;2019:5625026. doi: 10.1155/2019/5625026. eCollection 2019.
• [154] Retinoic Acid Receptor Knockdown Suppresses the Tumorigenicity of Esophageal Carcinoma via Wnt/-catenin Pathway.Dig Dis Sci. 2018 Dec;63(12):3348-3358. doi: 10.1007/s10620-018-5254-6. Epub 2018 Aug 28.
• [155] Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.J Pathol. 2020 Mar;250(3):288-298. doi: 10.1002/path.5369. Epub 2020 Jan 13.
• [156] MicroRNA-375 accelerates the invasion and migration of colorectal cancer through targeting RECK.Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4738-4745. doi: 10.26355/eurrev_201906_18055.
• [157] RGS16 is a marker for prognosis in colorectal cancer.Ann Surg Oncol. 2009 Dec;16(12):3507-14. doi: 10.1245/s10434-009-0690-3. Epub 2009 Sep 4.
• [158] Analysis of RGS2 expression and prognostic significance in stage II and III colorectal cancer.Biosci Rep. 2010 Dec;30(6):383-90. doi: 10.1042/BSR20090129.
• [159] Small nucleolar RNA host gene 1 promotes development and progression of colorectal cancer through negative regulation of miR-137.Mol Carcinog. 2019 Nov;58(11):2104-2117. doi: 10.1002/mc.23101. Epub 2019 Aug 30.
• [160] RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca(2+) Uptake and Promotes Colorectal Oncogenesis.Cancer Res. 2018 Jun 1;78(11):2876-2885. doi: 10.1158/0008-5472.CAN-17-3082. Epub 2018 Mar 12.
• [161] The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1.Cancer Lett. 2007 Jul 8;252(1):55-64. doi: 10.1016/j.canlet.2006.12.006. Epub 2007 Jan 16.
• [162] Robo1/Robo4: differential expression of angiogenic markers in colorectal cancer.Oncol Rep. 2006 Jun;15(6):1437-43.
• [163] Atractylenolide II reverses the influence of lncRNA XIST/miR-30a-5p/ROR1 axis on chemo-resistance of colorectal cancer cells.J Cell Mol Med. 2019 May;23(5):3151-3165. doi: 10.1111/jcmm.14148. Epub 2019 Mar 25.
• [164] Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers.Gut. 2000 Aug;47(2):268-71. doi: 10.1136/gut.47.2.268.
• [165] Detection of autoantibodies against Rabphilin-3A-like protein as a potential biomarker in patient's sera of colorectal cancer.Clin Chim Acta. 2011 Jul 15;412(15-16):1417-22. doi: 10.1016/j.cca.2011.04.020. Epub 2011 Apr 19.
• [166] The association of aberrant expression of NLRP3 and p-S6K1 in colorectal cancer.Pathol Res Pract. 2020 Jan;216(1):152737. doi: 10.1016/j.prp.2019.152737. Epub 2019 Nov 11.
• [167] Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancer.Oncol Rep. 2003 Sep-Oct;10(5):1375-80.
• [168] TRAIL inhibits platelet-induced colorectal cancer cell invasion.J Int Med Res. 2019 Feb;47(2):962-972. doi: 10.1177/0300060518820785. Epub 2019 Jan 9.
• [169] Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: a case control study.BMC Med Genet. 2008 Jul 21;9:70. doi: 10.1186/1471-2350-9-70.
• [170] Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindreds.Cancer Res. 1991 Aug 15;51(16):4135-40.
• [171] Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans.Biochim Biophys Acta. 2005 Jun 30;1741(1-2):215-23. doi: 10.1016/j.bbadis.2005.04.002.
• [172] Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse.Appl Immunohistochem Mol Morphol. 2019 Mar;27(3):185-194. doi: 10.1097/PAI.0000000000000557.
• [173] Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.Oncogene. 2001 Feb 22;20(8):1005-9. doi: 10.1038/sj.onc.1204211.
• [174] SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.J Cell Mol Med. 2019 May;23(5):3118-3129. doi: 10.1111/jcmm.14134. Epub 2019 Feb 14.
• [175] A novel serine protease SNC19 associated with human colorectal cancer.Chin Med J (Engl). 2001 Jul;114(7):726-30.
• [176] NMI promotes cell proliferation through TGF/Smad pathway by upregulating STAT1 in colorectal cancer.J Cell Physiol. 2020 Jan;235(1):429-441. doi: 10.1002/jcp.28983. Epub 2019 Jun 23.
• [177] Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer.Int J Cancer. 2007 Nov 15;121(10):2192-7. doi: 10.1002/ijc.22953.
• [178] Malignant transformation of rat embryo fibroblasts by cotransfection with eleven human mutant p53 cDNAs and activated H-ras gene.Oncogene. 1995 Oct 5;11(7):1339-45.
• [179] 1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours.Oncotarget. 2019 Jun 4;10(38):3725-3744. doi: 10.18632/oncotarget.26966. eCollection 2019 Jun 4.
• [180] Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer.Oncogene. 2007 May 17;26(23):3387-94. doi: 10.1038/sj.onc.1210116. Epub 2006 Nov 13.
• [181] Rho GDP-dissociation inhibitor is a potential prognostic biomarker and controls telomere regulation in colorectal cancer.Cancer Sci. 2017 Jul;108(7):1293-1302. doi: 10.1111/cas.13259. Epub 2017 May 31.
• [182] 4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 re-Expression.Cancers (Basel). 2018 Aug 10;10(8):269. doi: 10.3390/cancers10080269.
• [183] Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway.Cancer Manag Res. 2019 Jul 9;11:6323-6341. doi: 10.2147/CMAR.S198911. eCollection 2019.
• [184] LncRNA CASC9 interacts with CPSF3 to regulate TGF- signaling in colorectal cancer.J Exp Clin Cancer Res. 2019 Jun 11;38(1):249. doi: 10.1186/s13046-019-1263-3.
• [185] Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer.J Natl Cancer Inst. 2019 Aug 1;111(8):828-836. doi: 10.1093/jnci/djy215.
• [186] TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages.Cancer Lett. 2020 Jan 28;469:173-185. doi: 10.1016/j.canlet.2019.10.020. Epub 2019 Oct 17.
• [187] Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression.Eur J Cancer. 2010 Oct;46(15):2849-57. doi: 10.1016/j.ejca.2010.07.017. Epub 2010 Aug 19.
• [188] Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers.Int J Oncol. 2007 Jan;30(1):91-5.
• [189] Correlation Between Baseline Osteoprotegerin Serum Levels and Prognosis of Advanced-Stage Colorectal Cancer Patients.Cell Physiol Biochem. 2018;45(2):605-613. doi: 10.1159/000487101. Epub 2018 Jan 29.
• [190] APC truncating mutations in Middle Eastern Population: Tankyrase inhibitor is an effective strategy to sensitize APC mutant CRC To 5-FU chemotherapy.Biomed Pharmacother. 2020 Jan;121:109572. doi: 10.1016/j.biopha.2019.109572. Epub 2019 Nov 5.
• [191] Modulation of matrix metalloproteinase-7 (matrilysin) secretion in coculture of human colon carcinoma cells with fibroblasts from orthotopic and ectopic organs.Oncol Res. 1997;9(3):101-9.
• [192] TRPM8: a potential target for cancer treatment.J Cancer Res Clin Oncol. 2016 Sep;142(9):1871-81. doi: 10.1007/s00432-015-2112-1. Epub 2016 Jan 23.
• [193] Death from early colorectal cancer is predicted by the presence of transcripts of the REG gene family.Br J Cancer. 2000 Jul;83(2):188-95. doi: 10.1054/bjoc.2000.1227.
• [194] CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) and P53 mutation pattern in sporadic colorectal cancer.Tumour Biol. 2016 Feb;37(2):1707-14. doi: 10.1007/s13277-015-3902-4. Epub 2015 Aug 28.
• [195] Effect of ZNF217 gene polymorphisms on colorectal cancer development in a Mexican population.Genet Mol Res. 2015 Jan 23;14(1):362-7. doi: 10.4238/2015.January.23.9.
• [196] APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.J Clin Invest. 2011 Nov;121(11):4526-36. doi: 10.1172/JCI45008. Epub 2011 Oct 10.
• [197] Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF--signaling pathway.Carcinogenesis. 2011 Mar;32(3):318-26. doi: 10.1093/carcin/bgq245. Epub 2010 Nov 18.
• [198] Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.Drug Metab Pharmacokinet. 2011;26(6):646-58. doi: 10.2133/dmpk.DMPK-11-SC-050. Epub 2011 Aug 16.
• [199] Estrogen and progesterone-related gene variants and colorectal cancer risk in women.BMC Med Genet. 2011 May 31;12:78. doi: 10.1186/1471-2350-12-78.
• [200] Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancer.Scand J Immunol. 2011 Feb;73(2):122-7. doi: 10.1111/j.1365-3083.2010.02480.x.
• [201] miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells.FEBS Lett. 2011 Oct 3;585(19):2998-3005. doi: 10.1016/j.febslet.2011.08.014. Epub 2011 Aug 26.
• [202] Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages.Cell Physiol Biochem. 2018;46(4):1693-1703. doi: 10.1159/000489245. Epub 2018 Apr 20.
• [203] p38-regulated FOXC1 stability is required for colorectal cancer metastasis.J Pathol. 2020 Feb;250(2):217-230. doi: 10.1002/path.5362. Epub 2019 Nov 28.
• [204] Identification and Validation of Stage-Associated Serum Biomarkers in Colorectal Cancer Using MS-Based Procedures.Proteomics Clin Appl. 2020 Jan;14(1):e1900052. doi: 10.1002/prca.201900052. Epub 2019 Sep 18.
• [205] ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer.J Biol Chem. 2018 Jul 13;293(28):11166-11178. doi: 10.1074/jbc.RA118.003187. Epub 2018 May 22.
• [206] Epsilon-Globin HBE1 Enhances Radiotherapy Resistance by Down-Regulating BCL11A in Colorectal Cancer Cells.Cancers (Basel). 2019 Apr 8;11(4):498. doi: 10.3390/cancers11040498.
• [207] Functional mismatch repair and inactive p53 drive sensitization of colorectal cancer cells to irinotecan via the IAP antagonist BV6.Arch Toxicol. 2019 Aug;93(8):2265-2277. doi: 10.1007/s00204-019-02513-7. Epub 2019 Jul 9.
• [208] Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis.Mol Cancer. 2018 Feb 15;17(1):23. doi: 10.1186/s12943-018-0762-8.
• [209] A network-based predictive gene expression signature for recurrence risks in stage II colorectal cancer.Cancer Med. 2020 Jan;9(1):179-193. doi: 10.1002/cam4.2642. Epub 2019 Nov 14.
• [210] Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood.Can J Gastroenterol Hepatol. 2018 Jun 11;2018:7436205. doi: 10.1155/2018/7436205. eCollection 2018.
• [211] M2 macrophages confer resistance to 5-fluorouracil in colorectal cancer through the activation of CCL22/PI3K/AKT signaling.Onco Targets Ther. 2019 Apr 18;12:3051-3063. doi: 10.2147/OTT.S198126. eCollection 2019.
• [212] Polydatin Exerts an Antitumor Effect Through Regulating the miR-382/PD-L1 Axis in Colorectal Cancer.Cancer Biother Radiopharm. 2020 Mar;35(2):83-91. doi: 10.1089/cbr.2019.2999. Epub 2019 Nov 22.
• [213] Serum miR-1301-3p, miR-335-5p, miR-28-5p, and their target B7-H3 may serve as novel biomarkers for colorectal cancer.J BUON. 2019 May-Jun;24(3):1120-1127.
• [214] Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells.Nat Commun. 2018 Aug 10;9(1):3212. doi: 10.1038/s41467-018-05694-4.
• [215] Discovery of common and rare genetic risk variants for colorectal cancer.Nat Genet. 2019 Jan;51(1):76-87. doi: 10.1038/s41588-018-0286-6. Epub 2018 Dec 3.
• [216] Anti-claudin-4 extracellular domain antibody enhances the antitumoral effects of chemotherapeutic and antibody drugs in colorectal cancer.Oncotarget. 2018 Dec 21;9(100):37367-37378. doi: 10.18632/oncotarget.26427. eCollection 2018 Dec 21.
• [217] High clusterin (CLU) mRNA expression levels in tumors of colorectal cancer patients predict a poor prognostic outcome.Clin Biochem. 2020 Jan;75:62-69. doi: 10.1016/j.clinbiochem.2019.10.008. Epub 2019 Oct 28.
• [218] LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result.Clin Colorectal Cancer. 2018 Jun;17(2):e217-e228. doi: 10.1016/j.clcc.2017.12.002. Epub 2017 Dec 12.
• [219] Role of COL6A3 in colorectal cancer.Oncol Rep. 2018 Jun;39(6):2527-2536. doi: 10.3892/or.2018.6331. Epub 2018 Mar 23.
• [220] KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development.J Cell Biochem. 2020 Apr;121(4):2901-2908. doi: 10.1002/jcb.29526. Epub 2019 Nov 6.
• [221] CRHR2/Ucn2 signaling is a novel regulator of miR-7/YY1/Fas circuitry contributing to reversal of colorectal cancer cell resistance to Fas-mediated apoptosis.Int J Cancer. 2018 Jan 15;142(2):334-346. doi: 10.1002/ijc.31064. Epub 2017 Oct 12.
• [222] Targeting of cathepsin C induces autophagic dysregulation that directs ER stress mediated cellular cytotoxicity in colorectal cancer cells.Cell Signal. 2018 Jun;46:92-102. doi: 10.1016/j.cellsig.2018.02.017. Epub 2018 Mar 1.
• [223] Distinctive profiles of tumor-infiltrating immune cells and association with intensity of infiltration in colorectal cancer.Oncol Lett. 2018 Mar;15(3):3876-3882. doi: 10.3892/ol.2018.7771. Epub 2018 Jan 10.
• [224] Overexpression of miR-215-3p sensitizes colorectal cancer to 5-fluorouracil induced apoptosis through regulating CXCR1.Eur Rev Med Pharmacol Sci. 2018 Nov;22(21):7240-7250. doi: 10.26355/eurrev_201811_16258.
• [225] KNK437 restricts the growth and metastasis of colorectal cancer via targeting DNAJA1/CDC45 axis.Oncogene. 2020 Jan;39(2):249-261. doi: 10.1038/s41388-019-0978-0. Epub 2019 Sep 2.
• [226] Clinicopathological significance of G9A expression in colorectal carcinoma.Oncol Lett. 2018 Jun;15(6):8611-8619. doi: 10.3892/ol.2018.8446. Epub 2018 Apr 10.
• [227] Application of the Ethyl Acetate Extract of Cichorium as a Potential Photosensitizer in Photodynamic Therapy Induces Apoptosis and Autophagy in Colorectal Cancer Cell Lines via the Protein Kinase R-Like Endoplasmic Reticulum Kinase Pathway.J Biomed Nanotechnol. 2019 Sep 1;15(9):1867-1880. doi: 10.1166/jbn.2019.2825.
• [228] A MYC-GCN2-eIF2 negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0. Epub 2019 Nov 4.
• [229] Smoking, alcohol and family history of cancer as risk factors for small intestinal neuroendocrine tumors: a systematic review and meta-analysis.Scand J Gastroenterol. 2017 Aug;52(8):797-802. doi: 10.1080/00365521.2017.1310290. Epub 2017 Apr 10.
• [230] "Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.J Pharmacol Exp Ther. 2018 Jul;366(1):205-219. doi: 10.1124/jpet.117.246900. Epub 2018 May 7.
• [231] Fibroblast growth factor 21 as a circulating biomarker at various stages of colorectal carcinogenesis.Br J Cancer. 2018 Nov;119(11):1374-1382. doi: 10.1038/s41416-018-0280-x. Epub 2018 Nov 14.
• [232] FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.J Immunol. 2019 May 15;202(10):3065-3075. doi: 10.4049/jimmunol.1801199. Epub 2019 Apr 12.
• [233] Evaluation of [(18)F]FDG/[(18)F]FLT/[(18)F]FMISO-based micro-positron emission tomography in detection of liver metastasis in human colorectal cancer.Nucl Med Biol. 2019 May-Jun;72-73:36-44. doi: 10.1016/j.nucmedbio.2019.07.004. Epub 2019 Jul 11.
• [234] PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A.Cancer Lett. 2018 Nov 1;436:28-37. doi: 10.1016/j.canlet.2018.08.011. Epub 2018 Aug 14.
• [235] Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer.Br J Cancer. 2018 Jul;119(2):230-240. doi: 10.1038/s41416-018-0153-3. Epub 2018 Jun 29.
• [236] MicroRNA (miR)-597-5p Inhibits Colon Cancer Cell Migration and Invasion by Targeting FOS-Like Antigen 2 (FOSL2).Front Oncol. 2019 Jun 12;9:495. doi: 10.3389/fonc.2019.00495. eCollection 2019.
• [237] Expression of trophic factors receptors during reinnervation after recurrent laryngeal nerve injury.Laryngoscope. 2019 Nov;129(11):2537-2542. doi: 10.1002/lary.27649. Epub 2019 Feb 27.
• [238] Investigation of GHSR and GHRL methylation in colorectal cancer.Epigenomics. 2018 Dec;10(12):1525-1539. doi: 10.2217/epi-2018-0030. Epub 2018 Jul 2.
• [239] Incretin-based Drugs and the Incidence of Colorectal Cancer in Patients with Type 2 Diabetes.Epidemiology. 2018 Mar;29(2):246-253. doi: 10.1097/EDE.0000000000000793.
• [240] Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation. BMC Microbiol. 2019 May 16;19(1):99.
• [241] HMGB1: an overview of its versatile roles in the pathogenesis of colorectal cancer.Cell Oncol (Dordr). 2020 Apr;43(2):177-193. doi: 10.1007/s13402-019-00477-5. Epub 2019 Nov 1.
• [242] Antibody-Based Targeting of Cell Surface GRP94 Specifically Inhibits Cetuximab-Resistant Colorectal Cancer Growth.Biomolecules. 2019 Nov 1;9(11):681. doi: 10.3390/biom9110681.
• [243] Heat shock protein beta 3 (HSPB3) is an unfavorable molecular biomarker in colorectal adenocarcinoma.Mol Carcinog. 2020 Jan;59(1):116-125. doi: 10.1002/mc.23133. Epub 2019 Nov 10.
• [244] Apigenin-mediated Alterations in Viability and Senescence of SW480 Colorectal Cancer Cells Persist in The Presence of L-thyroxine.Anticancer Agents Med Chem. 2019;19(12):1535-1542. doi: 10.2174/1871520619666190704102708.
• [245] Chitooligosaccharides Prevents the Development of Colitis-Associated Colorectal Cancer by Modulating the Intestinal Microbiota and Mycobiota.Front Microbiol. 2019 Sep 18;10:2101. doi: 10.3389/fmicb.2019.02101. eCollection 2019.
• [246] Protein Expression and Genetic Variation of IL32 and Association with Colorectal Cancer in Swedish Patients.Anticancer Res. 2018 Jan;38(1):321-328. doi: 10.21873/anticanres.12225.
• [247] T(H)9, T(H)17, and T(H)22 Cell Subsets and Their Main Cytokine Products in the Pathogenesis of Colorectal Cancer.Front Oncol. 2019 Oct 4;9:1002. doi: 10.3389/fonc.2019.01002. eCollection 2019.
• [248] -catenin regulates IRF3-mediated innate immune signalling in colorectal cancer.Cell Prolif. 2018 Oct;51(5):e12464. doi: 10.1111/cpr.12464. Epub 2018 Jul 13.
• [249] Prognostic significance of resident CD103(+)CD8(+)T cells in human colorectal cancer tissues.Acta Histochem. 2019 Jul;121(5):657-663. doi: 10.1016/j.acthis.2019.05.009. Epub 2019 May 30.
• [250] Investigation of JAM-A (rs790056) and LFA-1 (rs8058823) gene variants in Turkish colorectal cancer patients.Turk J Gastroenterol. 2019 Oct;30(10):872-876. doi: 10.5152/tjg.2019.19141.
• [251] PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via -catenin-dependent regulation of ZEB1.Br J Cancer. 2020 Feb;122(4):578-589. doi: 10.1038/s41416-019-0679-z. Epub 2019 Dec 12.
• [252] Mutual regulation of JAG2 and PRAF2 promotes migration and invasion of colorectal cancer cells uncoupled from epithelial-mesenchymal transition.Cancer Cell Int. 2019 Jun 11;19:160. doi: 10.1186/s12935-019-0871-5. eCollection 2019.
• [253] KCNMA1 Expression is Downregulated in Colorectal Cancer via Epigenetic Mechanisms.Cancers (Basel). 2019 Feb 19;11(2):245. doi: 10.3390/cancers11020245.
• [254] JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing -catenin signaling pathway.J Exp Clin Cancer Res. 2019 Oct 29;38(1):435. doi: 10.1186/s13046-019-1439-x.
• [255] Activating and inhibitory killer cell immunoglobulin like receptors (KIR) genes are involved in an increased susceptibility to colorectal adenocarcinoma and protection against invasion and metastasis.Immunobiology. 2019 Sep;224(5):681-686. doi: 10.1016/j.imbio.2019.06.002. Epub 2019 Jun 20.
• [256] The inhibitory receptor CD94/NKG2A on CD8(+) tumor-infiltrating lymphocytes in colorectal cancer: a promising new druggable immune checkpoint in the context of HLAE/2m overexpression.Mod Pathol. 2020 Mar;33(3):468-482. doi: 10.1038/s41379-019-0322-9. Epub 2019 Aug 13.
• [257] Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.Cancer Res. 2018 Sep 1;78(17):4839-4852. doi: 10.1158/0008-5472.CAN-17-3629. Epub 2018 Jul 6.
• [258] Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting -catenin nuclear translocation.Cell Death Dis. 2018 Jul 3;9(7):749. doi: 10.1038/s41419-018-0766-8.
• [259] Identification of genes with universally upregulated or downregulated expressions in colorectal cancer.J Gastroenterol Hepatol. 2019 May;34(5):880-889. doi: 10.1111/jgh.14529. Epub 2018 Dec 11.
• [260] MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells.Oncogene. 2018 Feb 22;37(8):1031-1040. doi: 10.1038/onc.2017.396. Epub 2017 Oct 30.
• [261] Clinical Evidence on the Interaction Between MLK4, KRAS and Microsatellite Instability to Determine the Prognosis of Early-Stage Colorectal Carcinoma.Cell Physiol Biochem. 2019;53(5):820-831. doi: 10.33594/000000175.
• [262] RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell.Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):259-272. doi: 10.1016/j.bbamcr.2017.11.005. Epub 2017 Nov 11.
• [263] Development of novel predictive miRNA/target gene pathways for colorectal cancer distance metastasis to the liver using a bioinformatic approach.PLoS One. 2019 Feb 26;14(2):e0211968. doi: 10.1371/journal.pone.0211968. eCollection 2019.
• [264] Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer.BMC Cancer. 2018 Jun 22;18(1):679. doi: 10.1186/s12885-018-4589-x.
• [265] Comparison of Microvessel Density Using Nestin and CD34 in Colorectal Cancer.Anticancer Res. 2018 Jul;38(7):3889-3895. doi: 10.21873/anticanres.12673.
• [266] The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68.Mol Cancer. 2018 Jul 31;17(1):110. doi: 10.1186/s12943-018-0860-7.
• [267] NCOA4-RET fusion in colorectal cancer: Therapeutic challenge using patient-derived tumor cell lines.J Cancer. 2018 Jul 30;9(17):3032-3037. doi: 10.7150/jca.26256. eCollection 2018.
• [268] Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer.PLoS One. 2018 Feb 6;13(2):e0192385. doi: 10.1371/journal.pone.0192385. eCollection 2018.
• [269] Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer.Expert Rev Clin Pharmacol. 2017 May;10(5):549-557. doi: 10.1080/17512433.2017.1292124. Epub 2017 Apr 10.
• [270] Metabolic targeting of HIF-1 potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer.Oncogene. 2020 Jan;39(2):414-427. doi: 10.1038/s41388-019-0999-8. Epub 2019 Sep 2.
• [271] Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma.Int J Mol Med. 2017 Jun;39(6):1371-1380. doi: 10.3892/ijmm.2017.2958. Epub 2017 Apr 20.
• [272] Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.Cancer Discov. 2018 May;8(5):632-647. doi: 10.1158/2159-8290.CD-17-0533. Epub 2018 Mar 2.
• [273] A systematic review and quantitative assessment of methylation biomarkers in fecal DNA and colorectal cancer and its precursor, colorectal adenoma.Mutat Res Rev Mutat Res. 2019 Jan-Mar;779:45-57. doi: 10.1016/j.mrrev.2019.01.003. Epub 2019 Jan 16.
• [274] miR-17-3P regulates the proliferation and survival of colon cancer cells by targeting Par4.Mol Med Rep. 2018 Jan;17(1):618-623. doi: 10.3892/mmr.2017.7863. Epub 2017 Oct 25.
• [275] Clinical significance of serum markers reflecting gastric function and H. pylori infection in colorectal cancer.J Cancer. 2019 May 21;10(10):2229-2236. doi: 10.7150/jca.27134. eCollection 2019.
• [276] Cytoplasmic Pin1 expression is correlated with poor prognosis in colorectal cancer.Pathol Res Pract. 2018 Nov;214(11):1848-1853. doi: 10.1016/j.prp.2018.09.018. Epub 2018 Sep 15.
• [277] Overexpression of PKMYT1 indicates the poor prognosis and enhances proliferation and tumorigenesis in non-small cell lung cancer via activation of Notch signal pathway.Eur Rev Med Pharmacol Sci. 2019 May;23(10):4210-4219. doi: 10.26355/eurrev_201905_17925.
• [278] Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients.Adv Med Sci. 2019 Sep;64(2):402-408. doi: 10.1016/j.advms.2019.07.001. Epub 2019 Jul 25.
• [279] Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma.PPAR Res. 2019 Jul 3;2019:7486727. doi: 10.1155/2019/7486727. eCollection 2019.
• [280] Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.PLoS One. 2018 Jan 2;13(1):e0190070. doi: 10.1371/journal.pone.0190070. eCollection 2018.
• [281] Prostaglandin E(2) Induces miR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression.Gastroenterology. 2020 Mar;158(4):971-984.e10. doi: 10.1053/j.gastro.2019.11.013. Epub 2019 Nov 14.
• [282] Expression of factors and key components associated with the PI3K signaling pathway in colon cancer.Oncol Lett. 2018 Apr;15(4):5465-5472. doi: 10.3892/ol.2018.8044. Epub 2018 Feb 13.
• [283] Luteolin suppresses colorectal cancer cell metastasis via regulation of the miR?84/pleiotrophin axis.Oncol Rep. 2019 Jul;42(1):131-141. doi: 10.3892/or.2019.7136. Epub 2019 Apr 24.
• [284] A mutant KRAS-induced factor REG4 promotes cancer stem cell properties via Wnt/-catenin signaling.Int J Cancer. 2020 May 15;146(10):2877-2890. doi: 10.1002/ijc.32728. Epub 2019 Nov 23.
• [285] Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.Oncogene. 2019 Sep;38(37):6429-6444. doi: 10.1038/s41388-019-0891-6. Epub 2019 Jul 22.
• [286] RNF6 Promotes Colorectal Cancer by Activating the Wnt/-Catenin Pathway via Ubiquitination of TLE3.Cancer Res. 2018 Apr 15;78(8):1958-1971. doi: 10.1158/0008-5472.CAN-17-2683. Epub 2018 Jan 26.
• [287] Circadian clock pathway genes associated with colorectal cancer risk and prognosis.Arch Toxicol. 2018 Aug;92(8):2681-2689. doi: 10.1007/s00204-018-2251-7. Epub 2018 Jul 2.
• [288] Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy.J Biol Chem. 2017 Jun 2;292(22):9136-9149. doi: 10.1074/jbc.M117.783365. Epub 2017 Apr 14.
• [289] Hepatocytes direct the formation of a pro-metastatic niche in the liver.Nature. 2019 Mar;567(7747):249-252. doi: 10.1038/s41586-019-1004-y. Epub 2019 Mar 6.
• [290] Expression of septin 2 and association with clinicopathological parameters in colorectal cancer.Oncol Lett. 2019 Sep;18(3):2376-2383. doi: 10.3892/ol.2019.10528. Epub 2019 Jun 26.
• [291] Histone-lysine N-methyltransferase SETD7 is a potential serum biomarker for colorectal cancer patients.EBioMedicine. 2018 Nov;37:134-143. doi: 10.1016/j.ebiom.2018.10.036. Epub 2018 Oct 22.
• [292] Expressions of IGF-1, ERK, GLUT4, IRS-1 in metabolic syndrome complicated with colorectal cancer and their associations with the clinical characteristics of CRC.Cancer Biomark. 2018;21(4):883-891. doi: 10.3233/CBM-170942.
• [293] Role of Amino Acid Transporter Expression as a Prognostic Marker in Patients With Surgically Resected Colorectal Cancer.Anticancer Res. 2019 May;39(5):2535-2543. doi: 10.21873/anticanres.13375.
• [294] Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.Gastroenterology. 2019 Apr;156(5):1455-1466. doi: 10.1053/j.gastro.2018.11.066. Epub 2018 Dec 6.
• [295] MiR-363-3p suppresses tumor growth and metastasis of colorectal cancer via targeting SphK2.Biomed Pharmacother. 2018 Sep;105:922-931. doi: 10.1016/j.biopha.2018.06.052. Epub 2018 Jun 19.
• [296] Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer.Front Pharmacol. 2019 Jun 6;10:588. doi: 10.3389/fphar.2019.00588. eCollection 2019.
• [297] Role of serine/threonine kinase 33 methylation in colorectal cancer and its clinical significance.Oncol Lett. 2018 Feb;15(2):2153-2160. doi: 10.3892/ol.2017.7614. Epub 2017 Dec 14.
• [298] Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.Nucleic Acids Res. 2017 Feb 17;45(3):1159-1176. doi: 10.1093/nar/gkw1026.
• [299] Pre-diagnostic plasma concentrations of Fibrinogen, sGPIIb/IIIa, sP-selectin, sThrombomodulin, Thrombopoietin in relation to cancer risk: Findings from a large prospective study.Int J Cancer. 2018 Dec 1;143(11):2659-2667. doi: 10.1002/ijc.31623. Epub 2018 Oct 9.
• [300] DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients.Oncoimmunology. 2018 Nov 10;8(2):e1542918. doi: 10.1080/2162402X.2018.1542918. eCollection 2019.
• [301] Identification of key tumorigenesisrelated genes and their microRNAs in colon cancer.Oncol Rep. 2018 Dec;40(6):3551-3560. doi: 10.3892/or.2018.6726. Epub 2018 Sep 21.
• [302] [(18)F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer.ACS Med Chem Lett. 2018 Feb 21;9(3):177-181. doi: 10.1021/acsmedchemlett.7b00367. eCollection 2018 Mar 8.
• [303] The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.Int J Cancer. 2019 Aug 15;145(4):1138-1147. doi: 10.1002/ijc.32198. Epub 2019 Mar 2.
• [304] Expression of the inhibitory B7 family molecule VISTA in human colorectal carcinoma tumors.Cancer Immunol Immunother. 2018 Nov;67(11):1685-1694. doi: 10.1007/s00262-018-2227-8. Epub 2018 Aug 20.
• [305] The transcriptional and mutational landscapes of lipid metabolism-related genes in colon cancer.Oncotarget. 2017 Dec 21;9(5):5919-5930. doi: 10.18632/oncotarget.23592. eCollection 2018 Jan 19.
• [306] ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin-1-dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone.Mol Oncol. 2018 Oct;12(10):1735-1752. doi: 10.1002/1878-0261.12367. Epub 2018 Sep 17.
• [307] Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer.Biosci Rep. 2018 Feb 21;38(1):BSR20171428. doi: 10.1042/BSR20171428. Print 2018 Feb 28.
• [308] A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients.Sci Rep. 2017 Aug 1;7(1):7059. doi: 10.1038/s41598-017-07491-3.
• [309] Integrated transcriptomic analysis of distance-related field cancerization in rectal cancer patients.Oncotarget. 2017 May 15;8(37):61107-61117. doi: 10.18632/oncotarget.17864. eCollection 2017 Sep 22.
• [310] Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer.Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806905. doi: 10.1177/1533033818806905.
• [311] CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis.Oncogene. 2019 Feb;38(9):1560-1575. doi: 10.1038/s41388-018-0519-2. Epub 2018 Oct 18.
• [312] Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer.World J Surg Oncol. 2015 Feb 12;13:42. doi: 10.1186/s12957-015-0440-x.
• [313] ACR Appropriateness Criteria() PretreatmentStaging of Colorectal Cancer.J Am Coll Radiol. 2017 May;14(5S):S234-S244. doi: 10.1016/j.jacr.2017.02.012.
• [314] The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway.EBioMedicine. 2019 Nov;49:55-71. doi: 10.1016/j.ebiom.2019.10.039. Epub 2019 Nov 1.
• [315] Does the expression of the ACVR2A gene affect the development of colorectal cancer?.Genet Mol Biol. 2019 Jan-Mar;42(1):32-39. doi: 10.1590/1678-4685-GMB-2017-0332. Epub 2019 Mar 11.
• [316] Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study.Clin Colorectal Cancer. 2018 Sep;17(3):e471-e488. doi: 10.1016/j.clcc.2018.03.006. Epub 2018 Mar 14.
• [317] Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary Results.Dis Markers. 2019 Sep 2;2019:5035234. doi: 10.1155/2019/5035234. eCollection 2019.
• [318] ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer.Tumour Biol. 2017 Mar;39(3):1010428317695024. doi: 10.1177/1010428317695024.
• [319] Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer.BMC Cancer. 2014 Aug 7;14:568. doi: 10.1186/1471-2407-14-568.
• [320] Single nucleotide polymorphisms within MicroRNAs, MicroRNA targets, and MicroRNA biogenesis genes and their impact on colorectal cancer survival.Genes Chromosomes Cancer. 2017 Apr;56(4):285-295. doi: 10.1002/gcc.22434. Epub 2017 Jan 25.
• [321] Epigenetic silencing of ADAMTS5 is associated with increased invasiveness and poor survival in patients with colorectal cancer.J Cancer Res Clin Oncol. 2018 Feb;144(2):215-227. doi: 10.1007/s00432-017-2545-9. Epub 2017 Nov 15.
• [322] A perspective profile of ADCY1 in cAMP signaling with drug-resistance in lung cancer.J Cancer. 2019 Nov 1;10(27):6848-6857. doi: 10.7150/jca.36614. eCollection 2019.
• [323] Metformin suppresses CRC growth by inducing apoptosis via ADORA1.Front Biosci (Landmark Ed). 2017 Jan 1;22(2):248-257. doi: 10.2741/4484.
• [324] SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer.Gut. 2019 Jan;68(1):118-129. doi: 10.1136/gutjnl-2017-314983. Epub 2017 Nov 7.
• [325] AGR2 is controlled by DNMT3a-centered signaling module and mediates tumor resistance to 5-Aza in colorectal cancer.Exp Cell Res. 2019 Dec 1;385(1):111644. doi: 10.1016/j.yexcr.2019.111644. Epub 2019 Oct 12.
• [326] Multicenter fresh frozen tissue sampling in colorectal cancer: does the quality meet the standards for state of the art biomarker research?.Cell Tissue Bank. 2017 Sep;18(3):425-431. doi: 10.1007/s10561-017-9613-x. Epub 2017 Mar 3.
• [327] Association network analysis identifies enzymatic components of gut microbiota that significantly differ between colorectal cancer patients and healthy controls.PeerJ. 2019 Jul 29;7:e7315. doi: 10.7717/peerj.7315. eCollection 2019.
• [328] Aldose Reductase Inhibitor, Fidarestat Prevents High-fat Diet-induced Intestinal Polyps in Apc(Min/+) Mice.Curr Cancer Drug Targets. 2018;18(9):905-911. doi: 10.2174/1568009617666170808105633.
• [329] MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.Cancer Cell Int. 2018 Sep 3;18:124. doi: 10.1186/s12935-018-0628-6. eCollection 2018.
• [330] Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.J Cell Physiol. 2018 Feb;233(2):727-735. doi: 10.1002/jcp.25981. Epub 2017 Jul 11.
• [331] Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy.Theranostics. 2019 Jul 9;9(17):4878-4892. doi: 10.7150/thno.36254. eCollection 2019.
• [332] Expression patterns and prognostic value of m(6)A-related genes in colorectal cancer.Am J Transl Res. 2019 Jul 15;11(7):3972-3991. eCollection 2019.
• [333] Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the Colon Cancer Family Registry.Carcinogenesis. 2014 Sep;35(9):2121-6. doi: 10.1093/carcin/bgu119. Epub 2014 Jun 7.
• [334] Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway.Biochem Biophys Res Commun. 2019 Sep 10;517(1):1-7. doi: 10.1016/j.bbrc.2018.01.061. Epub 2018 Jan 13.
• [335] Angiogenin promotes colorectal cancer metastasis via tiRNA production.Int J Cancer. 2019 Sep 1;145(5):1395-1407. doi: 10.1002/ijc.32245. Epub 2019 Mar 28.
• [336] Efficacy of a Bispecific Antibody Co-Targeting VEGFA and Ang-2 in Combination with Chemotherapy in a Chemoresistant Colorectal Carcinoma Xenograft Model.Molecules. 2019 Aug 7;24(16):2865. doi: 10.3390/molecules24162865.
• [337] High Expression of Angiopoietin-like Protein 4 in Advanced Colorectal Cancer and its Association with Regulatory T Cells and M2 Macrophages.Pathol Oncol Res. 2020 Apr;26(2):1269-1278. doi: 10.1007/s12253-019-00695-0. Epub 2019 Jul 1.
• [338] Annexin A10 is a marker for the serrated pathway of colorectal carcinoma.Virchows Arch. 2015 Jan;466(1):5-12. doi: 10.1007/s00428-014-1683-6. Epub 2014 Nov 14.
• [339] Annexin A2 Enhances the Progression of Colorectal Cancer and Hepatocarcinoma via Cytoskeleton Structural Rearrangements.Microsc Microanal. 2019 Aug;25(4):950-960. doi: 10.1017/S1431927619000679. Epub 2019 Jun 7.
• [340] Physalis peruviana-Derived 4-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo.Molecules. 2019 Mar 22;24(6):1146. doi: 10.3390/molecules24061146.
• [341] Evaluation of serum and tissue levels of VAP-1 in colorectal cancer.BMC Cancer. 2016 Feb 24;16:154. doi: 10.1186/s12885-016-2183-7.
• [342] Hsa_circ_0009361 acts as the sponge of miR-582 to suppress colorectal cancer progression by regulating APC2 expression.Clin Sci (Lond). 2019 May 30;133(10):1197-1213. doi: 10.1042/CS20190286. Print 2019 May 31.
• [343] Evaluation of Apelin and Apelin Receptor Level in the Primary Tumor and Serum of Colorectal Cancer Patients.J Clin Med. 2019 Sep 20;8(10):1513. doi: 10.3390/jcm8101513.
• [344] Serum Apolipoprotein A-I Combined With C-Reactive Protein Serves As A Novel Prognostic Stratification System For Colorectal Cancer.Cancer Manag Res. 2019 Oct 30;11:9265-9276. doi: 10.2147/CMAR.S215599. eCollection 2019.
• [345] Potential early clinical stage colorectal cancer diagnosis using a proteomics blood test panel.Clin Proteomics. 2019 Aug 28;16:34. doi: 10.1186/s12014-019-9255-z. eCollection 2019.
• [346] Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer.Sci Rep. 2017 Jul 14;7(1):5374. doi: 10.1038/s41598-017-05415-9.
• [347] Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells.Oncotarget. 2017 Aug 10;8(68):112426-112441. doi: 10.18632/oncotarget.20113. eCollection 2017 Dec 22.
• [348] Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation.Epigenetics. 2019 Feb;14(2):158-170. doi: 10.1080/15592294.2019.1580112. Epub 2019 Feb 20.
• [349] AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer.Cell Death Dis. 2017 Jun 22;8(6):e2894. doi: 10.1038/cddis.2017.282.
• [350] Overexpression of Arginase-1 is an indicator of poor prognosis in patients with colorectal cancer.Pathol Res Pract. 2019 Jun;215(6):152383. doi: 10.1016/j.prp.2019.03.012. Epub 2019 Mar 5.
• [351] MicroRNA-296 inhibits colorectal cancer cell growth and enhances apoptosis by targeting ARRB1-mediated AKT activation.Oncol Rep. 2019 Jan;41(1):619-629. doi: 10.3892/or.2018.6806. Epub 2018 Oct 18.
• [352] Effect of Long-Term Mesalamine Therapy on Cancer-Associated Gene Expression in Colonic Mucosa of Patients with Ulcerative Colitis.Dig Dis Sci. 2019 Mar;64(3):740-750. doi: 10.1007/s10620-018-5378-8. Epub 2018 Nov 26.
• [353] Interaction of arylsulfatases A and B with maspin: A possible explanation for dysregulation of tumor cell metabolism and invasive potential of colorectal cancer.World J Clin Cases. 2019 Dec 6;7(23):3990-4003. doi: 10.12998/wjcc.v7.i23.3990.
• [354] MicroRNA-143-3p inhibits colorectal cancer metastases by targeting ITGA6 and ASAP3.Cancer Sci. 2019 Feb;110(2):805-816. doi: 10.1111/cas.13910. Epub 2019 Jan 4.
• [355] Inhibitory ASIC2-mediated calcineurin/NFAT against colorectal cancer by triterpenoids extracted from Rhus chinensis Mill.J Ethnopharmacol. 2019 May 10;235:255-267. doi: 10.1016/j.jep.2019.02.029. Epub 2019 Feb 14.
• [356] KRAS mutations in non-small-cell lung cancer and colorectal cancer: implications for EGFR-targeted therapies.Lung Cancer. 2014 Feb;83(2):163-7. doi: 10.1016/j.lungcan.2013.11.010. Epub 2013 Nov 21.
• [357] SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis.Cell Death Dis. 2019 Mar 11;10(3):239. doi: 10.1038/s41419-019-1481-9.
• [358] ATAD2 silencing decreases VEGFA secretion through targeting has-miR-520a to inhibit angiogenesis in colorectal cancer.Biochem Cell Biol. 2018 Dec;96(6):761-768. doi: 10.1139/bcb-2018-0081. Epub 2018 Jun 29.
• [359] Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity.Front Physiol. 2018 Sep 10;9:1125. doi: 10.3389/fphys.2018.01125. eCollection 2018.
• [360] Glucose deprivation induces chemoresistance in colorectal cancer cells by increasing ATF4 expression.World J Gastroenterol. 2016 Jul 21;22(27):6235-45. doi: 10.3748/wjg.v22.i27.6235.
• [361] miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7.Med Mol Morphol. 2017 Jun;50(2):76-85. doi: 10.1007/s00795-016-0150-7. Epub 2016 Dec 15.
• [362] Prognosis Prediction of Colorectal Cancer Using Gene Expression Profiles.Front Oncol. 2019 Apr 9;9:252. doi: 10.3389/fonc.2019.00252. eCollection 2019.
• [363] Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy.Int J Cancer. 2009 Jun 15;124(12):2905-10. doi: 10.1002/ijc.24273.
• [364] Novel Common Genetic Susceptibility Loci for Colorectal Cancer.J Natl Cancer Inst. 2019 Feb 1;111(2):146-157. doi: 10.1093/jnci/djy099.
• [365] Effect of sodium salt of Butrin, a novel compound isolated from Butea monosperma flowers on suppressing the expression of SIRT1 and Aurora B kinase-mediated apoptosis in colorectal cancer cells.Biomed Pharmacother. 2017 Jun;90:402-413. doi: 10.1016/j.biopha.2017.03.086. Epub 2017 Apr 5.
• [366] Preclinical Efficacy of [V4 Q5 ]dDAVP, a Second Generation Vasopressin Analog, on Metastatic Spread and Tumor-Associated Angiogenesis in Colorectal Cancer.Cancer Res Treat. 2019 Apr;51(2):438-450. doi: 10.4143/crt.2018.040. Epub 2018 Jun 1.
• [367] Predictive biomarkers of colorectal cancer.Comput Biol Chem. 2019 Dec;83:107106. doi: 10.1016/j.compbiolchem.2019.107106. Epub 2019 Sep 3.
• [368] Immune checkpoint blockade resistance-related B2M hotspot mutations in microsatellite-unstable colorectal carcinoma.Pathol Res Pract. 2019 Jan;215(1):209-214. doi: 10.1016/j.prp.2018.11.014. Epub 2018 Nov 24.
• [369] Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis.Cancer Biomark. 2020;27(2):163-171. doi: 10.3233/CBM-190828.
• [370] Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3/NF-B signaling pathway.Cancer Gene Ther. 2020 May;27(5):368-377. doi: 10.1038/s41417-019-0098-6. Epub 2019 Jun 11.
• [371] Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival.J Cancer Res Clin Oncol. 2018 Sep;144(9):1741-1750. doi: 10.1007/s00432-018-2701-x. Epub 2018 Jul 10.
• [372] Novel Epigenetic CREB-miR-630 Signaling Axis Regulates Radiosensitivity in Colorectal Cancer.PLoS One. 2015 Aug 11;10(8):e0133870. doi: 10.1371/journal.pone.0133870. eCollection 2015.
• [373] The kallikrein-Kinin system modulates the progression of colorectal liver metastases in a mouse model.BMC Cancer. 2018 Apr 4;18(1):382. doi: 10.1186/s12885-018-4260-6.
• [374] TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/-catenin degradation and is targeted for GSK3B/GSK3-mediated phosphorylation and degradation.Autophagy. 2019 Sep;15(9):1506-1522. doi: 10.1080/15548627.2019.1586250. Epub 2019 Mar 4.
• [375] Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.Cancer Lett. 2016 Oct 28;381(2):341-8. doi: 10.1016/j.canlet.2016.08.008. Epub 2016 Aug 15.
• [376] SCORE: Shared care of Colorectal cancer survivors: protocol for a randomised controlled trial.Trials. 2017 Oct 30;18(1):506. doi: 10.1186/s13063-017-2245-4.
• [377] Expression of BMP6 is associated with its methylation status in colorectal cancer tissue but lacks prognostic significance.Asian Pac J Cancer Prev. 2014;15(17):7091-5. doi: 10.7314/apjcp.2014.15.17.7091.
• [378] Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation.Br J Cancer. 2015 Aug 11;113(4):686-92. doi: 10.1038/bjc.2015.281. Epub 2015 Aug 6.
• [379] Dual PI3K-BRD4 Inhibitor SF1126 Inhibits Colorectal Cancer Cell Growth in Vitro and in Vivo.Cell Physiol Biochem. 2019;52(4):758-768. doi: 10.33594/000000053.
• [380] The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.Eur J Hum Genet. 2016 Oct;24(10):1501-5. doi: 10.1038/ejhg.2016.44. Epub 2016 May 11.
• [381] Putative Tumor Suppressor Genes EGR1 and BRSK1 Are Mutated in Gastric and Colorectal Cancers.Oncology. 2016;91(5):289-294. doi: 10.1159/000450616. Epub 2016 Sep 28.
• [382] The inhibitory role of miR?85?p in colorectal cancer proliferation and invasion via targeting of CD147.Oncol Rep. 2018 May;39(5):2201-2208. doi: 10.3892/or.2018.6309. Epub 2018 Mar 12.
• [383] Overexpression of Transmembrane Protein BST2 is Associated with Poor Survival of Patients with Esophageal, Gastric, or Colorectal Cancer.Ann Surg Oncol. 2017 Feb;24(2):594-602. doi: 10.1245/s10434-016-5100-z. Epub 2016 Feb 1.
• [384] Association between co-inhibitory molecule gene tagging single nucleotide polymorphisms and the risk of colorectal cancer in Chinese.J Cancer Res Clin Oncol. 2015 Sep;141(9):1533-44. doi: 10.1007/s00432-015-1915-4. Epub 2015 Jan 22.
• [385] Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease.Gastroenterology. 2016 Aug;151(2):278-287.e6. doi: 10.1053/j.gastro.2016.04.001. Epub 2016 Apr 8.
• [386] Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP-WT1-TBL1 axis.Gut. 2016 Sep;65(9):1482-93. doi: 10.1136/gutjnl-2014-308614. Epub 2015 Jun 12.
• [387] Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal cancer in Koreans.Oncotarget. 2017 Mar 28;8(13):21253-21265. doi: 10.18632/oncotarget.15512.
• [388] Prognostic value of carbonic anhydrase VII expression in colorectal carcinoma.BMC Cancer. 2015 Apr 1;15:209. doi: 10.1186/s12885-015-1216-y.
• [389] Radiolabeling of the antibody IgG M75 for epitope of human carbonic anhydrase IX by (61)Cu and (64)Cu and its biological testing.Appl Radiat Isot. 2019 Jan;143:87-97. doi: 10.1016/j.apradiso.2018.10.021. Epub 2018 Oct 25.
• [390] Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.Tumour Biol. 2011 Aug;32(4):653-9. doi: 10.1007/s13277-011-0165-6. Epub 2011 Apr 6.
• [391] Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer.Oncotarget. 2017 Apr 18;8(16):26755-26770. doi: 10.18632/oncotarget.15815.
• [392] Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer.Br J Cancer. 2015 Dec 22;113(12):1730-4. doi: 10.1038/bjc.2015.401. Epub 2015 Dec 3.
• [393] Is there a correlation between peripheral blood expression of angiogenic transcriptional factors/receptors and colorectal cancer?.J BUON. 2015 Sep-Oct;20(5):1193-200.
• [394] Overexpression of calpain? predicts poor outcome in patients with colorectal cancer and promotes tumor cell progression associated with downregulation of FLNA.Oncol Rep. 2019 Jun;41(6):3424-3434. doi: 10.3892/or.2019.7121. Epub 2019 Apr 16.
• [395] Coactivator-associated arginine methyltransferase 1 promotes cell growth and is targeted by microRNA-195-5p in human colorectal cancer.Tumour Biol. 2017 Mar;39(3):1010428317694305. doi: 10.1177/1010428317694305.
• [396] Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis.Cells. 2019 Dec 12;8(12):1622. doi: 10.3390/cells8121622.
• [397] Mutational analysis of caspase 1, 4, and 5 genes in common human cancers.Hum Pathol. 2008 Jun;39(6):895-900. doi: 10.1016/j.humpath.2007.10.015. Epub 2008 Apr 21.
• [398] Unbiased proteomic and transcript analyses reveal that stathmin-1 silencing inhibits colorectal cancer metastasis and sensitizes to 5-fluorouracil treatment.Mol Cancer Res. 2014 Dec;12(12):1717-28. doi: 10.1158/1541-7786.MCR-14-0088-T. Epub 2014 Jul 25.
• [399] DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas.Oncotarget. 2017 May 18;8(31):51387-51401. doi: 10.18632/oncotarget.17988. eCollection 2017 Aug 1.
• [400] The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.Eur J Cancer. 2010 Aug;46(12):2304-13. doi: 10.1016/j.ejca.2010.05.011. Epub 2010 Jun 9.
• [401] Overexpression of lncRNA TUSC7 reduces cell migration and invasion in colorectal cancer.Oncol Rep. 2019 Jun;41(6):3386-3392. doi: 10.3892/or.2019.7106. Epub 2019 Apr 9.
• [402] MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer.Int J Cancer. 2012 Sep 1;131(5):1042-51. doi: 10.1002/ijc.26485. Epub 2011 Nov 28.
• [403] lncRNAu50535 promotes the progression of lung cancer by activating CCL20/ERK signaling.Oncol Rep. 2019 Nov;42(5):1946-1956. doi: 10.3892/or.2019.7302. Epub 2019 Sep 5.
• [404] Overexpressed CXCR4 and CCR7 on the surface of NK92 cell have improved migration and anti-tumor activity in human colon tumor model.Anticancer Drugs. 2020 Apr;31(4):333-344. doi: 10.1097/CAD.0000000000000868.
• [405] Aberrant activation of CYR61 enhancers in colorectal cancer development.J Exp Clin Cancer Res. 2019 May 22;38(1):213. doi: 10.1186/s13046-019-1217-9.
• [406] MiR-218 regulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF.Cancer Cell Int. 2018 Jun 8;18:83. doi: 10.1186/s12935-018-0575-2. eCollection 2018.
• [407] CCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer.Cancer Manag Res. 2018 Oct 31;10:5113-5124. doi: 10.2147/CMAR.S176833. eCollection 2018.
• [408] In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells.J Inorg Biochem. 2017 Dec;177:27-38. doi: 10.1016/j.jinorgbio.2017.08.024. Epub 2017 Sep 6.
• [409] Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis.Mol Cancer Res. 2015 Aug;13(8):1185-96. doi: 10.1158/1541-7786.MCR-15-0014. Epub 2015 May 1.
• [410] Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis.Clin Cancer Res. 2017 Feb 1;23(3):833-844. doi: 10.1158/1078-0432.CCR-16-0520. Epub 2016 Aug 4.
• [411] Effect of Chemokine (C-C Motif) Ligand 7 (CCL7) and Its Receptor (CCR2) Expression on Colorectal Cancer Behaviors.Int J Mol Sci. 2019 Feb 5;20(3):686. doi: 10.3390/ijms20030686.
• [412] CCR6 promotes tumor angiogenesis via the AKT/NF-B/VEGF pathway in colorectal cancer.Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):387-397. doi: 10.1016/j.bbadis.2017.10.033. Epub 2017 Oct 31.
• [413] Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.Nat Biotechnol. 2015 Jun;33(6):656-60. doi: 10.1038/nbt.3239. Epub 2015 May 25.
• [414] The NK1 receptor antagonist NKP608 inhibits proliferation of human colorectal cancer cells via Wnt signaling pathway.Biol Res. 2018 May 30;51(1):14. doi: 10.1186/s40659-018-0163-x.
• [415] Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis.Mol Cancer. 2019 Mar 30;18(1):64. doi: 10.1186/s12943-019-0976-4.
• [416] Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer.J Natl Cancer Inst. 2014 Jan;106(1):djt322. doi: 10.1093/jnci/djt322. Epub 2013 Nov 22.
• [417] Identification of CD200+ colorectal cancer stem cells and their gene expression profile.Oncol Rep. 2016 Oct;36(4):2252-60. doi: 10.3892/or.2016.5039. Epub 2016 Aug 24.
• [418] Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome.Int J Cancer. 2013 Nov 15;133(10):2325-33. doi: 10.1002/ijc.28251. Epub 2013 May 29.
• [419] CD44 epithelial isoform inversely associates with invasive characteristics of colorectal cancer.Biomark Med. 2019 Apr;13(6):419-426. doi: 10.2217/bmm-2018-0337. Epub 2019 Apr 3.
• [420] Prognostic values of tumor endothelial markers in patients with colorectal cancer.World J Gastroenterol. 2005 Mar 7;11(9):1283-6. doi: 10.3748/wjg.v11.i9.1283.
• [421] Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population.Am J Clin Nutr. 2015 Jun;101(6):1295-304. doi: 10.3945/ajcn.115.107219. Epub 2015 May 6.
• [422] LncRNA TINCR/microRNA-107/CD36 regulates cell proliferation and apoptosis in colorectal cancer via PPAR signaling pathway based on bioinformatics analysis.Biol Chem. 2019 Apr 24;400(5):663-675. doi: 10.1515/hsz-2018-0236.
• [423] Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers.Oncotarget. 2016 Jun 21;7(25):38210-38223. doi: 10.18632/oncotarget.9427.
• [424] A novel therapeutic antiCD55 monoclonal antibody inhibits the proliferation and metastasis of colorectal cancer cells.Oncol Rep. 2019 Dec;42(6):2686-2693. doi: 10.3892/or.2019.7337. Epub 2019 Sep 26.
• [425] CD58, anovel surface marker, promotes self-renewal of tumor-initiating cells in colorectal cancer.Oncogene. 2015 Mar 19;34(12):1520-31. doi: 10.1038/onc.2014.95. Epub 2014 Apr 14.
• [426] Polymorphisms affecting micro-RNA regulation and associated with the risk of dietary-related cancers: a review from the literature and new evidence for a functional role of rs17281995 (CD86) and rs1051690 (INSR), previously associated with colorectal cancer.Mutat Res. 2011 Dec 1;717(1-2):109-15. doi: 10.1016/j.mrfmmm.2010.10.002. Epub 2010 Oct 30.
• [427] CBX8 and CD96 Are Important Prognostic Biomarkers of Colorectal Cancer.Med Sci Monit. 2018 Nov 1;24:7820-7827. doi: 10.12659/MSM.908656.
• [428] A functional role for Smad7 in sustaining colon cancer cell growth and survival.Cell Death Dis. 2014 Feb 20;5(2):e1073. doi: 10.1038/cddis.2014.49.
• [429] Circular RNA hsa_circRNA_102958 promotes tumorigenesis of colorectal cancer via miR-585/CDC25B axis.Cancer Manag Res. 2019 Jul 23;11:6887-6893. doi: 10.2147/CMAR.S212180. eCollection 2019.
• [430] Expression of huCdc7 in colorectal cancer.World J Gastroenterol. 2013 May 28;19(20):3130-3. doi: 10.3748/wjg.v19.i20.3130.
• [431] Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.PLoS Med. 2008 May 27;5(5):e114. doi: 10.1371/journal.pmed.0050114.
• [432] 6,7-Dihydroxy-2-(4'-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway.Drug Des Devel Ther. 2019 May 9;13:1609-1621. doi: 10.2147/DDDT.S193914. eCollection 2019.
• [433] Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.Oncotarget. 2017 Dec 28;9(4):5216-5232. doi: 10.18632/oncotarget.23749. eCollection 2018 Jan 12.
• [434] Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients.Cancers (Basel). 2019 Oct 11;11(10):1540. doi: 10.3390/cancers11101540.
• [435] A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery.J Comput Aided Mol Des. 2018 Jun;32(6):671-685. doi: 10.1007/s10822-018-0120-3. Epub 2018 May 8.
• [436] Targeting CDK9 for treatment of colorectal cancer.Mol Oncol. 2019 Oct;13(10):2178-2193. doi: 10.1002/1878-0261.12559. Epub 2019 Aug 21.
• [437] Sorting nexin 10 acts as a tumor suppressor in tumorigenesis and progression of colorectal cancer through regulating chaperone mediated autophagy degradation of p21(Cip1/WAF1).Cancer Lett. 2018 Apr 10;419:116-127. doi: 10.1016/j.canlet.2018.01.045.
• [438] Clinical value of combined detection of serum APE1-Aabs and CEACAM-1 in the diagnosis of colorectal cancer.Eur Rev Med Pharmacol Sci. 2018 Mar;22(5):1286-1289. doi: 10.26355/eurrev_201803_14469.
• [439] Identification of novel variants in colorectal cancer families by high-throughput exome sequencing.Cancer Epidemiol Biomarkers Prev. 2013 Jul;22(7):1239-51. doi: 10.1158/1055-9965.EPI-12-1226. Epub 2013 May 1.
• [440] Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs.Cancer Lett. 2016 Aug 1;378(1):51-8. doi: 10.1016/j.canlet.2016.04.041. Epub 2016 May 2.
• [441] Changes in lecithin: cholesterol acyltransferase, cholesteryl ester transfer protein and paraoxonase-1 activities in patients with colorectal cancer.Clin Biochem. 2019 Jan;63:32-38. doi: 10.1016/j.clinbiochem.2018.11.010. Epub 2018 Nov 28.
• [442] Alu-based cell-free DNA: a potential complementary biomarker for diagnosis of colorectal cancer.Clin Biochem. 2013 Jan;46(1-2):64-9. doi: 10.1016/j.clinbiochem.2012.08.026. Epub 2012 Sep 10.
• [443] Role of ion channels in gastrointestinal cancer.World J Gastroenterol. 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732.
• [444] Somatic mutations in cancer: Stochastic versus predictable.Mutat Res Genet Toxicol Environ Mutagen. 2017 Feb;814:37-46. doi: 10.1016/j.mrgentox.2016.12.006. Epub 2017 Jan 7.
• [445] Polymorphisms in the CHIT1 gene: Associations with colorectal cancer.Oncotarget. 2016 Jun 28;7(26):39572-39581. doi: 10.18632/oncotarget.9138.
• [446] Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma.Oncotarget. 2016 Oct 11;7(41):66660-66678. doi: 10.18632/oncotarget.11433.
• [447] Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-B, and Up-regulating Expression of MicroRNA-21.Gastroenterology. 2017 Mar;152(4):851-866.e24. doi: 10.1053/j.gastro.2016.11.018. Epub 2016 Nov 19.
• [448] CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling.Oncol Rep. 2016 Feb;35(2):999-1005. doi: 10.3892/or.2015.4462. Epub 2015 Nov 27.
• [449] Identification of a five-gene signature with prognostic value in colorectal cancer.J Cell Physiol. 2019 Apr;234(4):3829-3836. doi: 10.1002/jcp.27154. Epub 2018 Aug 21.
• [450] The Feasibility of 18-mm-Diameter Colonic Stents for Obstructive Colorectal Cancers.Oncology. 2017;93 Suppl 1:43-48. doi: 10.1159/000481229. Epub 2017 Dec 20.
• [451] PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial-mesenchymal transition.Br J Pharmacol. 2018 Aug;175(15):3111-3130. doi: 10.1111/bph.14352. Epub 2018 Jun 15.
• [452] Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway.Cell Death Differ. 2020 Jun;27(6):1765-1781. doi: 10.1038/s41418-019-0460-0. Epub 2019 Dec 4.
• [453] Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer.BMC Cancer. 2013 Sep 5;13:412. doi: 10.1186/1471-2407-13-412.
• [454] MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway. Oncotarget. 2017 Apr 4;8(14):22674-22684.
• [455] Overexpression of arginine transporter CAT-1 is associated with accumulation of L-arginine and cell growth in human colorectal cancer tissue.PLoS One. 2013 Sep 6;8(9):e73866. doi: 10.1371/journal.pone.0073866. eCollection 2013.
• [456] Homo Sapiens Circular RNA 0079993 (hsa_circ_0079993) of the POLR2J4 Gene Acts as an Oncogene in Colorectal Cancer Through the microRNA-203a-3p.1 and CREB1 Axis.Med Sci Monit. 2019 Sep 13;25:6872-6883. doi: 10.12659/MSM.916064.
• [457] LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer.Aging (Albany NY). 2018 Aug 22;10(8):2062-2078. doi: 10.18632/aging.101530.
• [458] GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.Clin Cancer Res. 2014 Jun 15;20(12):3094-106. doi: 10.1158/1078-0432.CCR-13-2774. Epub 2014 Apr 15.
• [459] Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation.FEBS Lett. 2005 Jul 4;579(17):3497-502. doi: 10.1016/j.febslet.2005.05.030.
• [460] Germline Genetic Variants in the Wnt/-Catenin Pathway as Predictors of Colorectal Cancer Risk.Cancer Epidemiol Biomarkers Prev. 2016 Mar;25(3):540-6. doi: 10.1158/1055-9965.EPI-15-0834. Epub 2016 Jan 25.
• [461] Investigation of fusion gene expression in HCT116 cells.Oncol Lett. 2017 Dec;14(6):6962-6968. doi: 10.3892/ol.2017.7055. Epub 2017 Sep 25.
• [462] miR-106b-5p inhibits the invasion and metastasis of colorectal cancer by targeting CTSA.Onco Targets Ther. 2018 Jul 4;11:3835-3845. doi: 10.2147/OTT.S172887. eCollection 2018.
• [463] Near-Infrared Fluorescent Activated Polymeric Probe for Imaging Intraluminal Colorectal Cancer Tumors.Biomacromolecules. 2019 Sep 9;20(9):3547-3556. doi: 10.1021/acs.biomac.9b00806. Epub 2019 Aug 21.
• [464] Increased expression of cathepsin D is required for L1-mediated colon cancer progression.Oncotarget. 2019 Aug 27;10(50):5217-5228. doi: 10.18632/oncotarget.27155. eCollection 2019 Aug 27.
• [465] Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.BMC Cancer. 2008 Jul 10;8:194. doi: 10.1186/1471-2407-8-194.
• [466] Vitamin D-Related Genes, Blood Vitamin D Levels and Colorectal Cancer Risk in Western European Populations.Nutrients. 2019 Aug 20;11(8):1954. doi: 10.3390/nu11081954.
• [467] Cullin 3 targets methionine adenosyltransferase II for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation.FEBS J. 2016 Jul;283(13):2390-402. doi: 10.1111/febs.13759. Epub 2016 Jun 6.
• [468] Loss of SMAD4 Promotes Colorectal Cancer Progression by Recruiting Tumor-Associated Neutrophils via the CXCL1/8-CXCR2 Axis.Clin Cancer Res. 2019 May 1;25(9):2887-2899. doi: 10.1158/1078-0432.CCR-18-3684. Epub 2019 Jan 31.
• [469] MicroRNA-144 mediates chronic inflammation and tumorigenesis in colorectal cancer progression via regulating C-X-C motif chemokine ligand 11.Exp Ther Med. 2018 Sep;16(3):1935-1943. doi: 10.3892/etm.2018.6389. Epub 2018 Jul 2.
• [470] Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile.Eur J Med Res. 2017 Oct 11;22(1):40. doi: 10.1186/s40001-017-0283-8.
• [471] Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.Gastroenterology. 2016 Jun;150(7):1633-1645. doi: 10.1053/j.gastro.2016.02.076. Epub 2016 Mar 8.
• [472] miR-30a promoter variation contributes to the increased risk of colorectal cancer in an Iranian population.J Cell Biochem. 2019 May;120(5):7734-7740. doi: 10.1002/jcb.28047. Epub 2018 Nov 1.
• [473] Overexpression of CYP2A6 in human colorectal tumors.Cancer Sci. 2007 Oct;98(10):1582-5. doi: 10.1111/j.1349-7006.2007.00572.x. Epub 2007 Aug 7.
• [474] Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells.Pharmacogenomics J. 2018 Jan;18(1):23-28. doi: 10.1038/tpj.2016.91. Epub 2017 Jan 3.
• [475] Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes.Endocr Relat Cancer. 2011 Jun 8;18(3):371-84. doi: 10.1530/ERC-11-0057. Print 2011 Jun.
• [476] Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.Oncotarget. 2016 Jul 19;7(29):46509-46527. doi: 10.18632/oncotarget.10224.
• [477] Cytohesins/ARNO: the function in colorectal cancer cells.PLoS One. 2014 Mar 11;9(3):e90997. doi: 10.1371/journal.pone.0090997. eCollection 2014.
• [478] Inhibition of LEF1-Mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness.Clin Cancer Res. 2019 Feb 15;25(4):1415-1429. doi: 10.1158/1078-0432.CCR-18-1232. Epub 2018 Nov 16.
• [479] O-GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5.J Cell Mol Med. 2019 Feb;23(2):1354-1362. doi: 10.1111/jcmm.14038. Epub 2018 Nov 28.
• [480] Epithelialmesenchymal transition in colorectal carcinoma cells is mediated by DEK/IMP3.Mol Med Rep. 2018 Jan;17(1):1065-1070. doi: 10.3892/mmr.2017.7943. Epub 2017 Nov 3.
• [481] Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.Int J Mol Med. 2016 Feb;37(2):319-28. doi: 10.3892/ijmm.2015.2427. Epub 2015 Dec 10.
• [482] PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis.Elife. 2019 Dec 16;8:e52135. doi: 10.7554/eLife.52135.
• [483] Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice.J Exp Med. 2017 Jun 5;214(6):1655-1662. doi: 10.1084/jem.20160442. Epub 2017 May 5.
• [484] Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A?G Polymorphism Relative to Colorectal Cancer Risk.Sci Rep. 2019 Mar 4;9(1):3406. doi: 10.1038/s41598-019-39747-5.
• [485] Metformin depresses overactivated Notch1/Hes1 signaling in colorectal cancer patients with type 2 diabetes mellitus.Anticancer Drugs. 2017 Jun;28(5):531-539. doi: 10.1097/CAD.0000000000000483.
• [486] Delta-like 4/Notch signaling promotes Apc (Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms.BMC Cancer. 2017 Jan 13;17(1):50. doi: 10.1186/s12885-016-3036-0.
• [487] DNase I enzyme-aided fluorescence signal amplification based on graphene oxide-DNA aptamer interactions for colorectal cancer exosome detection.Talanta. 2018 Jul 1;184:219-226. doi: 10.1016/j.talanta.2018.02.083. Epub 2018 Mar 29.
• [488] Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer.Cancer Cell Int. 2017 Aug 7;17:75. doi: 10.1186/s12935-017-0444-4. eCollection 2017.
• [489] Clinical impact of aspartyl aminopeptidase expression and activity in colorectal cancer.Transl Res. 2013 Nov;162(5):297-308. doi: 10.1016/j.trsl.2013.07.010. Epub 2013 Aug 13.
• [490] The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.Clin Epigenetics. 2019 Jan 7;11(1):4. doi: 10.1186/s13148-018-0601-1.
• [491] Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer.Br J Cancer. 2013 Aug 6;109(3):694-703. doi: 10.1038/bjc.2013.363. Epub 2013 Jul 9.
• [492] Dipeptidyl peptidase 4 inhibitors as novel agents in improving survival in diabetic patients with colorectal cancer and lung cancer: A Surveillance Epidemiology and Endpoint Research Medicare study.Cancer Med. 2019 Jul;8(8):3918-3927. doi: 10.1002/cam4.2278. Epub 2019 May 23.
• [493] Collapsin response mediator protein 2 is involved in regulating breast cancer progression.Breast Cancer. 2014 Nov;21(6):715-23. doi: 10.1007/s12282-013-0447-5. Epub 2013 Feb 5.
• [494] Revealing potential molecular targets bridging colitis and colorectal cancer based on multidimensional integration strategy.Oncotarget. 2015 Nov 10;6(35):37600-12. doi: 10.18632/oncotarget.6067.
• [495] Nuclear division cycle 80 promotes malignant progression and predicts clinical outcome in colorectal cancer.Cancer Med. 2018 Feb;7(2):420-432. doi: 10.1002/cam4.1284. Epub 2018 Jan 17.
• [496] Antisense Oligonucleotides against miR-21 Inhibit the Growth and Metastasis of Colorectal Carcinoma via the DUSP8 Pathway.Mol Ther Nucleic Acids. 2018 Dec 7;13:244-255. doi: 10.1016/j.omtn.2018.09.004. Epub 2018 Sep 13.
• [497] Development of a DUSP9 methylation screening assay.Pathol Oncol Res. 2015 Jan;21(1):123-30. doi: 10.1007/s12253-014-9797-3. Epub 2014 May 18.
• [498] LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells.Eur J Cell Biol. 2018 Jun;97(5):369-378. doi: 10.1016/j.ejcb.2018.04.005. Epub 2018 Apr 14.
• [499] Decrease of miR-622 expression suppresses migration and invasion by targeting regulation of DYRK2 in colorectal cancer cells.Onco Targets Ther. 2017 Feb 22;10:1091-1100. doi: 10.2147/OTT.S125724. eCollection 2017.
• [500] miR-503 inhibits cell proliferation and induces apoptosis in colorectal cancer cells by targeting E2F3.Int J Clin Exp Pathol. 2015 Oct 1;8(10):12853-60. eCollection 2015.
• [501] Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-.J Pineal Res. 2014 May;56(4):415-26. doi: 10.1111/jpi.12131. Epub 2014 Apr 15.
• [502] Aberrant methylated EDNRB can act as a potential diagnostic biomarker in sporadic colorectal cancer while KISS1 is controversial.Bioengineered. 2017 Sep 3;8(5):555-564. doi: 10.1080/21655979.2017.1283458. Epub 2017 Jan 31.
• [503] EED gene polymorphism in patients with colorectal cancer.Int J Biol Markers. 2013 Sep 27;28(3):274-9. doi: 10.5301/JBM.5000024.
• [504] Eukaryotic elongation factor-2 kinase expression is an independent prognostic factor in colorectal cancer.BMC Cancer. 2019 Jul 2;19(1):649. doi: 10.1186/s12885-019-5873-0.
• [505] Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab.Sci Rep. 2017 May 24;7(1):2388. doi: 10.1038/s41598-017-02538-x.
• [506] The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1 Levels and Colorectal Cancer Cell Survival under Hypoxia.Cell Rep. 2017 Feb 14;18(7):1699-1712. doi: 10.1016/j.celrep.2017.01.051.
• [507] An insertion/deletion polymorphism within the promoter of EGLN2 is associated with susceptibility to colorectal cancer.Int J Biol Markers. 2017 Jul 24;32(3):e274-e277. doi: 10.5301/jbm.5000253.
• [508] The extracellular matrix protein mindin attenuates colon cancer progression by blocking angiogenesis via Egr-1-mediated regulation.Oncogene. 2018 Feb 1;37(5):601-615. doi: 10.1038/onc.2017.359. Epub 2017 Oct 9.
• [509] Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition.Mol Cancer Res. 2019 Jan;17(1):42-53. doi: 10.1158/1541-7786.MCR-18-0650. Epub 2018 Sep 10.
• [510] CHIP/Stub1 interacts with eIF5A and mediates its degradation.Cell Signal. 2014 May;26(5):1098-104. doi: 10.1016/j.cellsig.2014.01.030. Epub 2014 Feb 6.
• [511] MiRNA-203 suppresses cell proliferation, migration and invasion in colorectal cancer via targeting of EIF5A2.Sci Rep. 2016 Jul 4;6:28301. doi: 10.1038/srep28301.
• [512] ALK and ROS1 overexpression is very rare in colorectal adenocarcinoma.Appl Immunohistochem Mol Morphol. 2015 Feb;23(2):134-8. doi: 10.1097/PAI.0000000000000025.
• [513] Endoglin Targeting in Colorectal Tumor Microenvironment.Clin Cancer Res. 2018 Dec 15;24(24):6110-6111. doi: 10.1158/1078-0432.CCR-18-2023. Epub 2018 Aug 3.
• [514] Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer.Oncotarget. 2017 Mar 28;8(13):21266-21280. doi: 10.18632/oncotarget.15072.
• [515] Expression of the EP300, TP53 and BAX genes in colorectal cancer: Correlations with clinicopathological parameters and survival.Oncol Rep. 2017 Jul;38(1):201-210. doi: 10.3892/or.2017.5687. Epub 2017 Jun 1.
• [516] MicroRNA-related transcription factor regulatory networks in human colorectal cancer.Medicine (Baltimore). 2019 Apr;98(15):e15158. doi: 10.1097/MD.0000000000015158.
• [517] Preclinical Evaluation of Chimeric Antigen Receptor-Modified T Cells Specific to Epithelial Cell Adhesion Molecule for Treating Colorectal Cancer.Hum Gene Ther. 2019 Apr;30(4):402-412. doi: 10.1089/hum.2018.229. Epub 2019 Mar 13.
• [518] Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma.Mol Oncol. 2019 Nov;13(11):2441-2459. doi: 10.1002/1878-0261.12576. Epub 2019 Oct 23.
• [519] Novel recurrently mutated genes in African American colon cancers.Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1149-54. doi: 10.1073/pnas.1417064112. Epub 2015 Jan 12.
• [520] The Diagnostic Significance of PDGF, EphA7, CCR5, and CCL5 Levels in Colorectal Cancer.Biomolecules. 2019 Sep 9;9(9):464. doi: 10.3390/biom9090464.
• [521] Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer.Genes Chromosomes Cancer. 2009 Mar;48(3):272-84. doi: 10.1002/gcc.20638.
• [522] Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer.Theranostics. 2019 Apr 12;9(8):2235-2251. doi: 10.7150/thno.30678. eCollection 2019.
• [523] Homoharringtonine suppresses LoVo cell growth by inhibiting EphB4 and the PI3K/AKT and MAPK/EKR1/2 signaling pathways. Food Chem Toxicol. 2020 Feb;136:110960. doi: 10.1016/j.fct.2019.110960. Epub 2019 Nov 11.
• [524] Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.Sci Rep. 2017 Mar 6;7:43702. doi: 10.1038/srep43702.
• [525] A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.Sci Rep. 2015 May 20;5:10442. doi: 10.1038/srep10442.
• [526] HER4 isoform CYT2 and its ligand NRG1III are expressed at high levels in human colorectal cancer.Oncol Lett. 2018 May;15(5):6629-6635. doi: 10.3892/ol.2018.8124. Epub 2018 Feb 27.
• [527] The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2 and IRE1/XBP-1 in colorectal cancer.Cell Death Dis. 2019 Jun 26;10(7):504. doi: 10.1038/s41419-019-1687-x.
• [528] Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.Epigenetics. 2019 May;14(5):477-493. doi: 10.1080/15592294.2019.1595998. Epub 2019 Mar 30.
• [529] Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin.Carcinogenesis. 2014 Nov;35(11):2474-84. doi: 10.1093/carcin/bgu157. Epub 2014 Jul 26.
• [530] Eyes absent homologue 2 predicts a favorable prognosis in colorectal cancer.Onco Targets Ther. 2018 Aug 8;11:4661-4671. doi: 10.2147/OTT.S164149. eCollection 2018.
• [531] Silencing of lncRNA EZR-AS1 inhibits proliferation, invasion, and migration of colorectal cancer cells through blocking transforming growth factor signaling.Biosci Rep. 2019 Nov 29;39(11):BSR20191199. doi: 10.1042/BSR20191199.
• [532] Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer.Clin Proteomics. 2018 Apr 9;15:15. doi: 10.1186/s12014-018-9191-3. eCollection 2018.
• [533] PAR2 deficiency enhances myeloid cell-mediated immunosuppression and promotes colitis-associated tumorigenesis.Cancer Lett. 2020 Jan 28;469:437-446. doi: 10.1016/j.canlet.2019.11.015. Epub 2019 Nov 14.
• [534] Tissue factor in ulcerative colitis, with and without concomitant primary sclerosing cholangitis.Ups J Med Sci. 2019 Nov;124(4):238-245. doi: 10.1080/03009734.2019.1689209. Epub 2019 Nov 27.
• [535] Clotting factor gene polymorphisms and colorectal cancer risk.J Clin Oncol. 2011 May 1;29(13):1722-7. doi: 10.1200/JCO.2010.31.8873. Epub 2011 Mar 21.
• [536] Crosstalk between TF/FVIIa and EGFR signaling in colorectal cancer cells.Cancer Biol Ther. 2019;20(4):454-460. doi: 10.1080/15384047.2018.1529123. Epub 2018 Nov 21.
• [537] miR?47 and miR?914 promote cancer progression equivalently by downregulating nuclear factor IX in colorectal cancer.Mol Med Rep. 2017 Dec;16(6):8189-8199. doi: 10.3892/mmr.2017.7675. Epub 2017 Sep 29.
• [538] Fatty acid-binding protein 1 is preferentially lost in microsatellite instable colorectal carcinomas and is immune modulated via the interferon pathway.Mod Pathol. 2017 Jan;30(1):123-133. doi: 10.1038/modpathol.2016.170. Epub 2016 Sep 30.
• [539] Gene Polymorphisms of ADIPOQ +45T>G, UCP2 -866G>A, and FABP2 Ala54Thr on the Risk of Colorectal Cancer: A Matched Case-Control Study.PLoS One. 2013 Jun 27;8(6):e67275. doi: 10.1371/journal.pone.0067275. Print 2013.
• [540] Pterostilbene Inhibits Adipocyte Conditioned-Medium-Induced Colorectal Cancer Cell Migration through Targeting FABP5-Related Signaling Pathway.J Agric Food Chem. 2019 Sep 18;67(37):10321-10329. doi: 10.1021/acs.jafc.9b03997. Epub 2019 Sep 3.
• [541] Familial aggregation of early-onset cancers.Int J Cancer. 2020 Apr 1;146(7):1791-1799. doi: 10.1002/ijc.32512. Epub 2019 Jun 27.
• [542] De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer.Mol Cancer Res. 2019 Jan;17(1):140-152. doi: 10.1158/1541-7786.MCR-18-0199. Epub 2018 Aug 28.
• [543] Adenoma detection rate metrics in colorectal cancer surveillance colonoscopy.Surg Endosc. 2018 Jul;32(7):3108-3113. doi: 10.1007/s00464-018-6025-3. Epub 2018 Jan 16.
• [544] Expression of long-chain fatty acid receptor GPR40 is associated with cancer progression in colorectal cancer: A retrospective study.Oncol Lett. 2018 Jun;15(6):8641-8646. doi: 10.3892/ol.2018.8383. Epub 2018 Mar 29.
• [545] Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma.Oncogene. 2013 Dec 5;32(49):5541-50. doi: 10.1038/onc.2013.264. Epub 2013 Jul 15.
• [546] Fibroblast growth factor-10 and epithelial-mesenchymal transition in colorectal cancer.EXCLI J. 2019 Jul 17;18:530-539. doi: 10.17179/excli2018-1784. eCollection 2019.
• [547] FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3/- catenin signaling cascade via FGFR4 activation.Oncotarget. 2016 Mar 22;7(12):13575-86. doi: 10.18632/oncotarget.6185.
• [548] Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer.PLoS One. 2017 Jul 27;12(7):e0180616. doi: 10.1371/journal.pone.0180616. eCollection 2017.
• [549] Neutralizing FGF4 protein in conditioned medium of IL-21-silenced HCT116 cells restores the migratory activity of the colorectal cancer cells.Cytotechnology. 2018 Oct;70(5):1363-1374. doi: 10.1007/s10616-018-0228-2. Epub 2018 May 25.
• [550] Molecular Modeling-(B)ased Delivery System Enhances Everolimus-Induced Apoptosis in Caco-2 Cells.ACS Omega. 2019 May 22;4(5):8767-8777. doi: 10.1021/acsomega.9b00109. eCollection 2019 May 31.
• [551] FGF8 promotes colorectal cancer growth and metastasis by activating YAP1.Oncotarget. 2015 Jan 20;6(2):935-52. doi: 10.18632/oncotarget.2822.
• [552] FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis.Oncotarget. 2018 Aug 14;9(63):32204-32218. doi: 10.18632/oncotarget.25941. eCollection 2018 Aug 14.
• [553] Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer.Oncotarget. 2019 Sep 3;10(51):5385-5386. doi: 10.18632/oncotarget.27186. eCollection 2019 Sep 3.
• [554] MAPK-mediated upregulation of fibrinogen-like protein 2 promotes proliferation, migration, and invasion of colorectal cancer cells.Cell Biol Int. 2019 Dec;43(12):1483-1491. doi: 10.1002/cbin.11198. Epub 2019 Jul 18.
• [555] Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer.Cell Signal. 2019 Apr;56:15-22. doi: 10.1016/j.cellsig.2019.01.007. Epub 2019 Jan 23.
• [556] Do FHIT gene alterations play a role in human solid tumors?.Asia Pac J Clin Oncol. 2018 Oct;14(5):e214-e223. doi: 10.1111/ajco.12868. Epub 2018 Mar 8.
• [557] Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer.Gastroenterol Res Pract. 2019 Apr 9;2019:3784172. doi: 10.1155/2019/3784172. eCollection 2019.
• [558] DNA methylation and expression of the folate transporter genes in colorectal cancer.Tumour Biol. 2015 Jul;36(7):5581-90. doi: 10.1007/s13277-015-3228-2. Epub 2015 Feb 21.
• [559] LncRNA-SNHG15 enhances cell proliferation in colorectal cancer by inhibiting miR-338-3p.Cancer Med. 2019 May;8(5):2404-2413. doi: 10.1002/cam4.2105. Epub 2019 Apr 3.
• [560] The inflammatory cytokine IL-6 induces FRA1 deacetylation promoting colorectal cancer stem-like properties.Oncogene. 2019 Jun;38(25):4932-4947. doi: 10.1038/s41388-019-0763-0. Epub 2019 Feb 25.
• [561] FOXC2 promotes colorectal cancer metastasis by directly targeting MET.Oncogene. 2015 Aug 13;34(33):4379-90. doi: 10.1038/onc.2014.368. Epub 2014 Nov 10.
• [562] Exploration of the mechanism of colorectal cancer metastasis using microarray analysis.Oncol Lett. 2017 Dec;14(6):6671-6677. doi: 10.3892/ol.2017.7044. Epub 2017 Sep 25.
• [563] FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression.Sci Rep. 2019 Feb 6;9(1):1505. doi: 10.1038/s41598-018-38017-0.
• [564] Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation.Integr Cancer Ther. 2019 Jan-Dec;18:1534735419846377. doi: 10.1177/1534735419846377.
• [565] Prognostic Impact of Tumor-Infiltrating Lymphocytes in Primary and Metastatic Colorectal Cancer: A Systematic Review and Meta-analysis.Dis Colon Rectum. 2019 Apr;62(4):498-508. doi: 10.1097/DCR.0000000000001332.
• [566] FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma.Am J Transl Res. 2017 May 15;9(5):2207-2218. eCollection 2017.
• [567] The Expression of Formyl Peptide Receptor 1 is Correlated with Tumor Invasion of Human Colorectal Cancer.Sci Rep. 2017 Jul 19;7(1):5918. doi: 10.1038/s41598-017-06368-9.
• [568] FPR2 enhances colorectal cancer progression by promoting EMT process.Neoplasma. 2019 Sep;66(5):785-791. doi: 10.4149/neo_2018_181123N890. Epub 2019 Jun 18.
• [569] Fucosylated TGF- receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells.Br J Cancer. 2014 Jan 7;110(1):156-63. doi: 10.1038/bjc.2013.699. Epub 2013 Nov 19.
• [570] Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer.Cell Death Dis. 2017 Jun 22;8(6):e2892. doi: 10.1038/cddis.2017.281.
• [571] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.Cancer Sci. 2009 Mar;100(3):405-12. doi: 10.1111/j.1349-7006.2008.01052.x. Epub 2008 Dec 24.
• [572] Structural and dynamic characterization of human Wnt2-Fzd7 complex using computational approaches.J Mol Model. 2018 Sep 6;24(10):274. doi: 10.1007/s00894-018-3788-3.
• [573] TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.Oncotarget. 2016 Aug 30;7(35):56355-56370. doi: 10.18632/oncotarget.10889.
• [574] Primary adenocarcinoma of the bladder lacks mismatch repair deficiency and demonstrates PD-L1 expression in tumor-infiltrating immune cells, with implications in both diagnosis and therapeutics.Hum Pathol. 2019 Dec;94:58-63. doi: 10.1016/j.humpath.2019.10.005. Epub 2019 Oct 27.
• [575] GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.Clin Cancer Res. 2009 Jun 15;15(12):3990-7. doi: 10.1158/1078-0432.CCR-09-0055. Epub 2009 Jun 9.
• [576] Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma.Int J Cancer. 2002 Jan 1;97(1):21-7. doi: 10.1002/ijc.1574.
• [577] KRAS insertions in colorectal cancer: what do we know about unusual KRAS mutations?.Exp Mol Pathol. 2014 Apr;96(2):257-60. doi: 10.1016/j.yexmp.2014.02.014. Epub 2014 Mar 2.
• [578] Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review).Oncol Rep. 2019 Dec;42(6):2228-2244. doi: 10.3892/or.2019.7351. Epub 2019 Oct 3.
• [579] Filtrating colorectal cancer associated genes by integrated analyses of global DNA methylation and hydroxymethylation in cancer and normal tissue.Sci Rep. 2016 Aug 22;6:31826. doi: 10.1038/srep31826.
• [580] DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer.Epigenetics. 2011 May;6(5):602-9. doi: 10.4161/epi.6.5.15237. Epub 2011 May 1.
• [581] Inhibition of GOT1 sensitizes colorectal cancer cells to 5-fluorouracil.Cancer Chemother Pharmacol. 2017 Apr;79(4):835-840. doi: 10.1007/s00280-017-3282-0. Epub 2017 Mar 17.
• [582] Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers.Mol Cancer Ther. 2018 Oct;17(10):2164-2175. doi: 10.1158/1535-7163.MCT-18-0026. Epub 2018 Aug 6.
• [583] Relation of glypican-3 and E-cadherin expressions to clinicopathological features and prognosis of mucinous and non-mucinous colorectal adenocarcinoma.Tumour Biol. 2015 Jun;36(6):4671-9. doi: 10.1007/s13277-015-3115-x. Epub 2015 Jan 27.
• [584] GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions.Oncotarget. 2017 Sep 6;8(48):84258-84275. doi: 10.18632/oncotarget.20653. eCollection 2017 Oct 13.
• [585] GPNMB methylation: a new marker of potentially carcinogenic colon lesions.BMC Cancer. 2018 Nov 6;18(1):1068. doi: 10.1186/s12885-018-4903-7.
• [586] Overexpression of G protein-coupled receptor 31 as a poor prognosticator in human colorectal cancer.World J Gastroenterol. 2018 Nov 7;24(41):4679-4690. doi: 10.3748/wjg.v24.i41.4679.
• [587] Immunohistochemical Expression of CD133 and LGR5 in Ulcerative Colitis-associated Colorectal Cancer and Dysplasia.In Vivo. 2019 Jul-Aug;33(4):1279-1284. doi: 10.21873/invivo.11600.
• [588] Evolution and heterogeneity of non-hereditary colorectal cancer revealed by single-cell exome sequencing.Oncogene. 2017 May 18;36(20):2857-2867. doi: 10.1038/onc.2016.438. Epub 2016 Dec 12.
• [589] The PEAK1-PPP1R12B axis inhibits tumor growth and metastasis by regulating Grb2/PI3K/Akt signalling in colorectal cancer.Cancer Lett. 2019 Feb 1;442:383-395. doi: 10.1016/j.canlet.2018.11.014. Epub 2018 Nov 22.
• [590] Knockdown of GRHL2 inhibited proliferation and induced apoptosis of colorectal cancer by suppressing the PI3K/Akt pathway.Gene. 2019 Jun 5;700:96-104. doi: 10.1016/j.gene.2019.03.051. Epub 2019 Mar 24.
• [591] Prognostic Value of Progranulin in Patients with Colorectal Cancer Treated with Curative Resection.Pathol Oncol Res. 2020 Jan;26(1):397-404. doi: 10.1007/s12253-018-0520-7. Epub 2018 Oct 30.
• [592] Antioxidant Barrier, Redox Status, and Oxidative Damage to Biomolecules in Patients with Colorectal Cancer. Can Malondialdehyde and Catalase Be Markers of Colorectal Cancer Advancement?.Biomolecules. 2019 Oct 22;9(10):637. doi: 10.3390/biom9100637.
• [593] Deletion and Single Nucleotide Polymorphisms in Common Glutathione-S Transferases Contribute to Colorectal Cancer Development.Pathol Oncol Res. 2019 Oct;25(4):1579-1587. doi: 10.1007/s12253-019-00589-1. Epub 2019 Jan 29.
• [594] Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia.Hum Pathol. 2019 May;87:103-114. doi: 10.1016/j.humpath.2018.11.032. Epub 2019 Feb 2.
• [595] The Impact of Immune Interaction on the Metastatic Infiltration of Colorectal Carcinoma to Lymph Nodes.Anticancer Res. 2018 Jul;38(7):4159-4167. doi: 10.21873/anticanres.12709.
• [596] Expression of HAX-1 in colorectal cancer and its role in cancer cell growth.Mol Med Rep. 2015 Sep;12(3):4071-4078. doi: 10.3892/mmr.2015.3905. Epub 2015 Jun 11.
• [597] MiR-761 inhibits colorectal cancer cell proliferation and invasion through targeting HDAC1.Pharmazie. 2019 Feb 1;74(2):111-114. doi: 10.1691/ph.2019.8756.
• [598] The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.Nat Commun. 2019 Feb 8;10(1):663. doi: 10.1038/s41467-018-08225-3.
• [599] MiR-489 suppresses tumor growth and invasion by targeting HDAC7 in colorectal cancer.Clin Transl Oncol. 2018 Jun;20(6):703-712. doi: 10.1007/s12094-017-1770-7. Epub 2017 Oct 25.
• [600] Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation.Curr Cancer Drug Targets. 2018;18(1):97-106. doi: 10.2174/1568009617666170206104032.
• [601] Gut Microbe-Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Luminal Histamine Production.Am J Pathol. 2017 Oct;187(10):2323-2336. doi: 10.1016/j.ajpath.2017.06.011. Epub 2017 Sep 13.
• [602] MicroRNA-511 Inhibits Cellular Proliferation and Invasion in Colorectal Cancer by Directly Targeting Hepatoma-Derived Growth Factor.Oncol Res. 2018 Oct 17;26(9):1355-1363. doi: 10.3727/096504018X15154094331876. Epub 2018 Jan 10.
• [603] Role of HGF/c-Met in the treatment of colorectal cancer with liver metastasis.J Biochem Mol Toxicol. 2019 Jun;33(6):e22316. doi: 10.1002/jbt.22316. Epub 2019 Mar 21.
• [604] HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation.Oncotarget. 2017 Mar 7;8(10):16744-16754. doi: 10.18632/oncotarget.14421.
• [605] The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.EBioMedicine. 2018 Jul;33:105-121. doi: 10.1016/j.ebiom.2018.07.002. Epub 2018 Jul 10.
• [606] Validation of immunogenic PASD1 peptides against HLA-A*24:02 colorectal cancer.Immunotherapy. 2019 Oct;11(14):1205-1219. doi: 10.2217/imt-2019-0073. Epub 2019 Sep 3.
• [607] Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.Cancer Res. 2016 Sep 1;76(17):5103-14. doi: 10.1158/0008-5472.CAN-15-2980. Epub 2016 Apr 20.
• [608] HLA-G as a new tumor biomarker: detection of soluble isoforms of HLA-G in the serum and saliva of patients with colorectal cancer.Clin Transl Oncol. 2020 Jul;22(7):1166-1171. doi: 10.1007/s12094-019-02244-2. Epub 2019 Nov 20.
• [609] PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways.Cancer Lett. 2019 May 28;450:1-13. doi: 10.1016/j.canlet.2019.02.022. Epub 2019 Feb 15.
• [610] miR-330 suppresses EMT and induces apoptosis by downregulating HMGA2 in human colorectal cancer.J Cell Physiol. 2020 Feb;235(2):920-931. doi: 10.1002/jcp.29007. Epub 2019 Jun 26.
• [611] Long noncoding RNA CRCMSL suppresses tumor invasive and metastasis in colorectal carcinoma through nucleocytoplasmic shuttling of HMGB2.Oncogene. 2019 Apr;38(16):3019-3032. doi: 10.1038/s41388-018-0614-4. Epub 2018 Dec 21.
• [612] Statin use and the risk of colorectal cancer in a population-based electronic health records study.Sci Rep. 2019 Sep 19;9(1):13560. doi: 10.1038/s41598-019-49877-5.
• [613] Potential Role of HMGCS2 in Tumor Angiogenesis in Colorectal Cancer and Its Potential Use as a Diagnostic Marker.Can J Gastroenterol Hepatol. 2019 Jul 1;2019:8348967. doi: 10.1155/2019/8348967. eCollection 2019.
• [614] Frameshift mutation of a histone methylation-related gene SETD1B and its regional heterogeneity in gastric and colorectal cancers with high microsatellite instability.Hum Pathol. 2014 Aug;45(8):1674-81. doi: 10.1016/j.humpath.2014.04.013. Epub 2014 Apr 24.
• [615] Heterogeneous nuclear ribonucleoprotein A1 promotes the expression of autophagy-related protein 6 in human colorectal cancer.Biochem Biophys Res Commun. 2019 May 21;513(1):255-260. doi: 10.1016/j.bbrc.2019.03.179. Epub 2019 Apr 3.
• [616] MicroRNA 196B Regulates HOXA5, HOXB6 and GLTP Expression Levels in Colorectal Cancer Cells.Pathol Oncol Res. 2019 Jul;25(3):953-959. doi: 10.1007/s12253-018-0399-3. Epub 2018 Mar 12.
• [617] Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.Front Oncol. 2019 Apr 2;9:216. doi: 10.3389/fonc.2019.00216. eCollection 2019.
• [618] Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis.Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G205-G216. doi: 10.1152/ajpgi.00212.2018. Epub 2018 Nov 21.
• [619] Deletion and down-regulation of HRH4 gene in gastric carcinomas: a potential correlation with tumor progression. PLoS One. 2012;7(2):e31207. doi: 10.1371/journal.pone.0031207. Epub 2012 Feb 20.
• [620] A variant (rs932335) in the HSD11B1 gene is associated with colorectal cancer in a Chinese population.Eur J Cancer Prev. 2013 Nov;22(6):523-8. doi: 10.1097/CEJ.0b013e3283656346.
• [621] Epithelial-specific deletion of 11-HSD2 hinders Apcmin/+ mouse tumorigenesis.Mol Cancer Res. 2013 Sep;11(9):1040-50. doi: 10.1158/1541-7786.MCR-13-0084-T. Epub 2013 Jun 5.
• [622] Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER.J Clin Endocrinol Metab. 2017 Dec 1;102(12):4435-4447. doi: 10.1210/jc.2016-3716.
• [623] Genomic and regulatory characteristics of significant transcription factors in colorectal cancer metastasis.Sci Rep. 2018 Dec 13;8(1):17836. doi: 10.1038/s41598-018-36168-8.
• [624] USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.Cell Death Dis. 2019 Dec 4;10(12):911. doi: 10.1038/s41419-019-2141-9.
• [625] Design and validation of an orally administrated active L. fermentum-L. acidophilus probiotic formulation using colorectal cancer Apc (Min/+) mouse model.Appl Microbiol Biotechnol. 2017 Mar;101(5):1999-2019. doi: 10.1007/s00253-016-7885-x. Epub 2016 Nov 11.
• [626] HTR1D, TIMP1, SERPINE1, MMP3 and CNR2 affect the survival of patients with colon adenocarcinoma.Oncol Lett. 2019 Sep;18(3):2448-2454. doi: 10.3892/ol.2019.10545. Epub 2019 Jun 28.
• [627] Expression of B7-H2 on CD8(+) T cells in colorectal cancer microenvironment and its clinical significance.Int Immunopharmacol. 2018 Mar;56:128-134. doi: 10.1016/j.intimp.2018.01.018. Epub 2018 Feb 2.
• [628] Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth.Cancer Gene Ther. 2020 Apr;27(3-4):235-245. doi: 10.1038/s41417-019-0089-7. Epub 2019 Mar 1.
• [629] Comprehensive analysis of human IgG Fc N-glycopeptides and construction of a screening model for colorectal cancer.J Proteomics. 2020 Feb 20;213:103616. doi: 10.1016/j.jprot.2019.103616. Epub 2019 Dec 14.
• [630] Anti-VEGFR2-interferon-2 regulates the tumor microenvironment and exhibits potent antitumor efficacy against colorectal cancer.Oncoimmunology. 2017 Feb 17;6(3):e1290038. doi: 10.1080/2162402X.2017.1290038. eCollection 2017.
• [631] Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes.J Immunother Cancer. 2019 Jun 22;7(1):157. doi: 10.1186/s40425-019-0635-8.
• [632] Sensitive glycoprofiling of insulin-like growth factor receptors isolated from colon tissue of patients with colorectal carcinoma using lectin-based protein microarray.Int J Biol Macromol. 2020 Feb 1;144:932-937. doi: 10.1016/j.ijbiomac.2019.09.170. Epub 2019 Oct 25.
• [633] Genomic copy number of a carcinogenic single nucleotide polymorphism at 8q24 in non-risk allele colorectal cancer associated with insulin growth factor 2 receptor expression.J Gastroenterol Hepatol. 2012 Apr;27 Suppl 3:95-9. doi: 10.1111/j.1440-1746.2012.07081.x.
• [634] Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer.PLoS One. 2016 May 6;11(5):e0155160. doi: 10.1371/journal.pone.0155160. eCollection 2016.
• [635] Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer.Oncol Lett. 2019 Dec;18(6):6284-6292. doi: 10.3892/ol.2019.10925. Epub 2019 Sep 26.
• [636] Association of IGFBP-6 Expression with Metabolic Syndrome and Adiponectin and IGF-IR Receptor Levels in Colorectal Cancer.Asian Pac J Cancer Prev. 2016;17(8):3963-9.
• [637] IGFBP-rP1 suppresses epithelial-mesenchymal transition and metastasis in colorectal cancer.Cell Death Dis. 2015 Mar 19;6(3):e1695. doi: 10.1038/cddis.2015.59.
• [638] Weekly High-dose 5-Fluorouracil as 24-hour Infusion Combined with Sodium Folinic Acid (AIO regimen) Plus Irinotecan in Second-line and Sequential Therapy of Metastatic Colorectal Cancer (CRC).Anticancer Res. 2017 Jul;37(7):3771-3779. doi: 10.21873/anticanres.11752.
• [639] Interaction analysis of IL-12A and IL-12B polymorphisms with the risk of colorectal cancer.Tumour Biol. 2015 Dec;36(12):9295-301. doi: 10.1007/s13277-015-3685-7. Epub 2015 Jun 24.
• [640] Interleukin-13 and its signaling pathway is associated with obesity-related colorectal tumorigenesis.Cancer Sci. 2019 Jul;110(7):2156-2165. doi: 10.1111/cas.14066. Epub 2019 Jun 18.
• [641] An IL13R2 peptide exhibits therapeutic activity against metastatic colorectal cancer.Br J Cancer. 2018 Oct;119(8):940-949. doi: 10.1038/s41416-018-0259-7. Epub 2018 Oct 15.
• [642] Histamine and Histaminergic Receptors in Colorectal Cancer: From Basic Science to Evidence-based Medicine.Anticancer Agents Med Chem. 2018;18(1):15-20. doi: 10.2174/1871520616666160321115349.
• [643] Association of polymorphisms in microRNA-binding sites and colorectal cancer in an Iranian population.Cancer Genet. 2012 Oct;205(10):501-7. doi: 10.1016/j.cancergen.2012.05.013. Epub 2012 Aug 29.
• [644] In Vitro Evaluation of CMV Specific CD8+T Cells Function in CMV+ Colorectal Cancer Patients Compared to Healthy Controls.Iran J Allergy Asthma Immunol. 2019 Aug 17;18(4):379-392. doi: 10.18502/ijaai.v18i4.1416.
• [645] Follicular helper T cells promote the effector functions of CD8(+) T cells via the provision of IL-21, which is downregulated due to PD-1/PD-L1-mediated suppression in colorectal cancer.Exp Cell Res. 2018 Nov 1;372(1):35-42. doi: 10.1016/j.yexcr.2018.09.006. Epub 2018 Sep 8.
• [646] Levels of peripheral Th17 cells and serum Th17-related cytokines in patients with colorectal cancer: a meta-analysis.Cell Mol Biol (Noisy-le-grand). 2018 May 15;64(6):94-102.
• [647] Therapeutic effects of the euglenoid ichthyotoxin, euglenophycin, in colon cancer.Oncotarget. 2017 Nov 1;8(61):104347-104358. doi: 10.18632/oncotarget.22238. eCollection 2017 Nov 28.
• [648] IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation.Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2646-2651. doi: 10.1073/pnas.1815016116. Epub 2019 Jan 29.
• [649] Prognostic significance of nomograms integrating IL-37 expression, neutrophil level, and MMR status in patients with colorectal cancer.Cancer Med. 2018 Aug;7(8):3682-3694. doi: 10.1002/cam4.1663. Epub 2018 Jul 13.
• [650] Elevated systemic interleukin-7 in patients with colorectal cancer and individuals at high risk of cancer: association with lymph node involvement and tumor location in the right colon.Cancer Immunol Immunother. 2017 Feb;66(2):171-179. doi: 10.1007/s00262-016-1933-3. Epub 2016 Nov 19.
• [651] Somatic mutation of IL7R exon 6 in acute leukemias and solid cancers.Hum Pathol. 2013 Apr;44(4):551-5. doi: 10.1016/j.humpath.2012.06.017. Epub 2012 Oct 12.
• [652] ILK Expression in Colorectal Cancer Is Associated with EMT, Cancer Stem Cell Markers and Chemoresistance.Cancer Genomics Proteomics. 2018 Mar-Apr;15(2):127-141. doi: 10.21873/cgp.20071.
• [653] IMP3 expression in biopsy specimens as a diagnostic biomarker for colorectal cancer.Hum Pathol. 2017 Jun;64:137-144. doi: 10.1016/j.humpath.2017.03.013. Epub 2017 Apr 13.
• [654] IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways.J Exp Clin Cancer Res. 2018 Dec 5;37(1):304. doi: 10.1186/s13046-018-0980-3.
• [655] A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.PLoS One. 2014 Feb 6;9(2):e87761. doi: 10.1371/journal.pone.0087761. eCollection 2014.
• [656] Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression.Cancer Epidemiol Biomarkers Prev. 2020 Jan;29(1):133-140. doi: 10.1158/1055-9965.EPI-19-0325. Epub 2019 Oct 30.
• [657] Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.EBioMedicine. 2017 Feb;15:36-47. doi: 10.1016/j.ebiom.2016.11.039. Epub 2016 Dec 3.
• [658] IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.JCI Insight. 2019 Oct 3;4(19):e130867. doi: 10.1172/jci.insight.130867.
• [659] LIN28B/IRS1 axis is targeted by miR-30a-5p and promotes tumor growth in colorectal cancer.J Cell Biochem. 2020 Aug;121(8-9):3720-3729. doi: 10.1002/jcb.29529. Epub 2019 Nov 12.
• [660] IRS-2 rs1805097 polymorphism is associated with the decreased risk of colorectal cancer.Oncotarget. 2017 Apr 11;8(15):25107-25114. doi: 10.18632/oncotarget.15342.
• [661] Involvement of the Integrin 11 in the Progression of Colorectal Cancer.Cancers (Basel). 2017 Jul 26;9(8):96. doi: 10.3390/cancers9080096.
• [662] High-Yield Methylation Markers for Stool-Based Detection of Colorectal Cancer.Dig Dis Sci. 2020 Jun;65(6):1710-1719. doi: 10.1007/s10620-019-05908-9. Epub 2019 Nov 12.
• [663] O-GlcNAcylation of ITGA5 facilitates the occurrence and development of colorectal cancer.Exp Cell Res. 2019 Sep 15;382(2):111464. doi: 10.1016/j.yexcr.2019.06.009. Epub 2019 Jun 13.
• [664] (6) -integrin serves as a novel serum tumor marker for colorectal carcinoma.Int J Cancer. 2019 Aug 1;145(3):678-685. doi: 10.1002/ijc.32137. Epub 2019 Jan 29.
• [665] miR19b-3p promotes the growth and metastasis of colorectal cancer via directly targeting ITGB8.Am J Cancer Res. 2017 Oct 1;7(10):1996-2008. eCollection 2017.
• [666] Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription.Cancer Res. 2019 May 1;79(9):2195-2207. doi: 10.1158/0008-5472.CAN-18-2133. Epub 2019 Mar 15.
• [667] JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer.J Exp Clin Cancer Res. 2019 Jan 22;38(1):28. doi: 10.1186/s13046-018-1019-5.
• [668] JAK2 regulates mismatch repair protein-mediated epigenetic alterations in response to oxidative damage.Environ Mol Mutagen. 2019 May;60(4):308-319. doi: 10.1002/em.22269. Epub 2019 Jan 7.
• [669] Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.Am J Cancer Res. 2018 May 1;8(5):852-865. eCollection 2018.
• [670] Alteration of microRNA-4474/4717 expression and CREB-binding protein in human colorectal cancer tissues infected with Fusobacterium nucleatum.PLoS One. 2019 Apr 5;14(4):e0215088. doi: 10.1371/journal.pone.0215088. eCollection 2019.
• [671] Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil.Neoplasia. 2019 Jun;21(6):557-570. doi: 10.1016/j.neo.2019.03.011. Epub 2019 Apr 28.
• [672] Long noncoding RNA kcna3 inhibits the progression of colorectal carcinoma through down-regulating YAP1 expression.Biomed Pharmacother. 2018 Nov;107:382-389. doi: 10.1016/j.biopha.2018.07.118. Epub 2018 Aug 9.
• [673] Genes CEP55, FOXD3, FOXF2, GNAO1, GRIA4, and KCNA5 as potential diagnostic biomarkers in colorectal cancer.BMC Med Genomics. 2019 Apr 15;12(1):54. doi: 10.1186/s12920-019-0501-z.
• [674] The combined activation of K(Ca)3.1 and inhibition of K(v)11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.Br J Cancer. 2018 Jan;118(2):200-212. doi: 10.1038/bjc.2017.392. Epub 2017 Nov 21.
• [675] A novel role for estrogen-induced signaling in the colorectal cancer gender bias.Ir J Med Sci. 2019 May;188(2):389-395. doi: 10.1007/s11845-018-1867-1. Epub 2018 Jul 17.
• [676] Somatic deletion of KDM1A/LSD1 gene is associated to advanced colorectal cancer stages.J Clin Pathol. 2020 Feb;73(2):107-111. doi: 10.1136/jclinpath-2019-206128. Epub 2019 Aug 30.
• [677] Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer.Nucleic Acids Res. 2019 Mar 18;47(5):2349-2364. doi: 10.1093/nar/gky1317.
• [678] Depletion of JARID1B induces cellular senescence in human colorectal cancer.Int J Oncol. 2013 Apr;42(4):1212-8. doi: 10.3892/ijo.2013.1799. Epub 2013 Jan 25.
• [679] The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer.Ann Surg Oncol. 2016 Feb;23(2):678-85. doi: 10.1245/s10434-015-4879-3. Epub 2015 Sep 28.
• [680] p62 functions as an oncogene in colorectal cancer through inhibiting apoptosis and promoting cell proliferation by interacting with the vitamin D receptor.Cell Prolif. 2019 May;52(3):e12585. doi: 10.1111/cpr.12585. Epub 2019 Feb 22.
• [681] KIF11 Is Required for Spheroid Formation by Oesophageal and Colorectal Cancer Cells.Anticancer Res. 2017 Jan;37(1):47-55. doi: 10.21873/anticanres.11287.
• [682] Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer.J Exp Clin Cancer Res. 2015 Feb 5;34(1):13. doi: 10.1186/s13046-015-0129-6.
• [683] Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage.J Transl Med. 2016 Aug 12;14(1):239. doi: 10.1186/s12967-016-1001-y.
• [684] The Relationship Between Killer Cell Immunoglobulin-Like Receptors and HLA-C Polymorphisms in Colorectal Cancer in a Saudi Population.Genet Test Mol Biomarkers. 2015 Nov;19(11):617-22. doi: 10.1089/gtmb.2015.0105. Epub 2015 Sep 18.
• [685] miR-7-5p regulates the proliferation and migration of colorectal cancer cells by negatively regulating the expression of Krppel-like factor 4.Oncol Lett. 2019 Mar;17(3):3241-3246. doi: 10.3892/ol.2019.10001. Epub 2019 Feb 1.
• [686] Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein.Oncotarget. 2019 Oct 22;10(58):6062-6078. doi: 10.18632/oncotarget.27153. eCollection 2019 Oct 22.
• [687] Clinical significance of human kallikrein7 gene expression in colorectal cancer.Ann Surg Oncol. 2010 Nov;17(11):3037-42. doi: 10.1245/s10434-010-1132-y. Epub 2010 Jun 11.
• [688] Elevated expression of KLK8 predicts poor prognosis in colorectal cancer.Biomed Pharmacother. 2017 Apr;88:595-602. doi: 10.1016/j.biopha.2017.01.112. Epub 2017 Jan 28.
• [689] Antitumor activity of NKG2D CAR-T cells against human colorectal cancer cells in vitro and in vivo.Am J Cancer Res. 2019 May 1;9(5):945-958. eCollection 2019.
• [690] Association of an miR-502-binding site polymorphism in the 3'-untranslated region of SET8 with colorectal cancer.Oncol Lett. 2019 Apr;17(4):3960-3964. doi: 10.3892/ol.2019.10026. Epub 2019 Feb 7.
• [691] Identification of Kininogen 1 as a Serum Protein Marker of Colorectal Adenoma in Patients with a Family History of Colorectal Cancer.J Cancer. 2018 Mar 8;9(3):540-547. doi: 10.7150/jca.22405. eCollection 2018.
• [692] Karyopherin 1 deletion suppresses tumor growth and metastasis in colorectal cancer (CRC) by reducing MET expression.Biomed Pharmacother. 2019 Dec;120:109127. doi: 10.1016/j.biopha.2019.109127. Epub 2019 Oct 17.
• [693] Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer.Int J Cancer. 2015 Apr 1;136(7):1515-27. doi: 10.1002/ijc.29140. Epub 2014 Sep 3.
• [694] L1CAM expression in colorectal cancer identifies a high-risk group of patients with dismal prognosis already in early-stage disease.Acta Oncol. 2020 Jan;59(1):55-59. doi: 10.1080/0284186X.2019.1667022. Epub 2019 Sep 18.
• [695] Identification and Characterization of CD107a as a Marker of Low Reactive Oxygen Species in Chemoresistant Cells in Colorectal Cancer.Ann Surg Oncol. 2017 Apr;24(4):1110-1119. doi: 10.1245/s10434-016-5671-8. Epub 2016 Nov 10.
• [696] Overexpression of LARP1 predicts poor prognosis of colorectal cancer and is expected to be a potential therapeutic target.Tumour Biol. 2016 Nov;37(11):14585-14594. doi: 10.1007/s13277-016-5332-3. Epub 2016 Sep 10.
• [697] COPS5 and LASP1 synergistically interact to downregulate 14-3-3 expression and promote colorectal cancer progression via activating PI3K/AKT pathway.Int J Cancer. 2018 May 1;142(9):1853-1864. doi: 10.1002/ijc.31206. Epub 2017 Dec 27.
• [698] Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway.Cancer Cell Int. 2019 Apr 11;19:97. doi: 10.1186/s12935-019-0812-3. eCollection 2019.
• [699] [Corrigendum] Lipocalin2 inversely regulates TRAIL sensitivity through p38 MAPKmediated DR5 regulation in colorectal cancer.Int J Oncol. 2019 May;54(5):1897. doi: 10.3892/ijo.2019.4748. Epub 2019 Mar 13.
• [700] Genotyping of the lactase-phlorizin hydrolase c/t-13910 polymorphism by means of a new rapid denaturing high-performance liquid chromatography-based assay in healthy subjects and colorectal cancer patients.J Biomol Screen. 2007 Aug;12(5):733-9. doi: 10.1177/1087057107301328. Epub 2007 May 3.
• [701] LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc.Nat Commun. 2019 Aug 2;10(1):3499. doi: 10.1038/s41467-019-11447-8.
• [702] Leptin rs2167270 G?A (G19A) polymorphism may decrease the risk of cancer: A case-control study and meta-analysis involving 19?89 subjects.J Cell Biochem. 2019 Jul;120(7):10998-11007. doi: 10.1002/jcb.28378. Epub 2019 Jan 29.
• [703] Expression of leptin and leptin receptors in colorectal cancer-an immunohistochemical study.PeerJ. 2019 Oct 2;7:e7624. doi: 10.7717/peerj.7624. eCollection 2019.
• [704] Chelate-soluble pectin fraction from papaya pulp interacts with galectin-3 and inhibits colon cancer cell proliferation.Int J Biol Macromol. 2019 Apr 1;126:170-178. doi: 10.1016/j.ijbiomac.2018.12.191. Epub 2018 Dec 22.
• [705] Nuclear legumain activity in colorectal cancer.PLoS One. 2013;8(1):e52980. doi: 10.1371/journal.pone.0052980. Epub 2013 Jan 10.
• [706] GPR48, a poor prognostic factor, promotes tumor metastasis and activates -catenin/TCF signaling in colorectal cancer.Carcinogenesis. 2013 Dec;34(12):2861-9. doi: 10.1093/carcin/bgt229. Epub 2013 Jun 26.
• [707] The evolution of surgical treatment for gastrointestinal cancers.Int J Clin Oncol. 2019 Nov;24(11):1333-1349. doi: 10.1007/s10147-019-01499-7. Epub 2019 Sep 14.
• [708] LIFR promotes tumor angiogenesis by up-regulating IL-8 levels in colorectal cancer.Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2769-2784. doi: 10.1016/j.bbadis.2018.05.004. Epub 2018 May 9.
• [709] TRIP6, as a target of miR-7, regulates the proliferation and metastasis of colorectal cancer cells.Biochem Biophys Res Commun. 2019 Jun 18;514(1):231-238. doi: 10.1016/j.bbrc.2019.04.092. Epub 2019 Apr 24.
• [710] Immunoglobulinlike transcript 4 and human leukocyte antigenG interaction promotes the progression of human colorectal cancer.Int J Oncol. 2019 Jun;54(6):1943-1954. doi: 10.3892/ijo.2019.4761. Epub 2019 Mar 22.
• [711] Expression of ILT3 predicts poor prognosis and is inversely associated with infiltration of CD45RO+ T cells in patients with colorectal cancer.Pathol Res Pract. 2018 Oct;214(10):1621-1625. doi: 10.1016/j.prp.2018.07.026. Epub 2018 Jul 27.
• [712] Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128.Oncogene. 2019 Jan;38(2):164-179. doi: 10.1038/s41388-018-0432-8. Epub 2018 Aug 3.
• [713] High-fat diet feeding and palmitic acid increase CRC growth in 2AR-dependent manner.Cell Death Dis. 2019 Sep 26;10(10):711. doi: 10.1038/s41419-019-1958-6.
• [714] LMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer.Sci Rep. 2016 Oct 25;6:36050. doi: 10.1038/srep36050.
• [715] Label-Free Nanoplasmonic Biosensing of Cancer Biomarkers for Clinical Diagnosis.Methods Mol Biol. 2019;2027:115-140. doi: 10.1007/978-1-4939-9616-2_10.
• [716] Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.Thorac Cancer. 2018 Jul;9(7):785-793. doi: 10.1111/1759-7714.12645. Epub 2018 May 15.
• [717] Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer.Oncol Rep. 2018 Aug;40(2):932-942. doi: 10.3892/or.2018.6452. Epub 2018 May 21.
• [718] Gene expression profiling demonstrates WNT/-catenin pathway genes alteration in Mexican patients with colorectal cancer and diabetes mellitus.J BUON. 2017 Sep-Oct;22(5):1107-1114.
• [719] Inhibition of LTA4H by bestatin in human and mouse colorectal cancer.EBioMedicine. 2019 Jun;44:361-374. doi: 10.1016/j.ebiom.2019.05.008. Epub 2019 May 10.
• [720] Mediatory role of BLT2 in the proliferation of KRAS mutant colorectal cancer cells.Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):329-336. doi: 10.1016/j.bbamcr.2018.12.006. Epub 2018 Dec 13.
• [721] Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma.PLoS One. 2011;6(12):e27399. doi: 10.1371/journal.pone.0027399. Epub 2011 Dec 13.
• [722] Expression analysis of lymphangiogenic factors in human colorectal cancer with quantitative RT-PCR.Cancer Invest. 2007 Sep;25(6):393-6. doi: 10.1080/07357900701508934.
• [723] MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer.Sci Rep. 2015 Jul 17;5:12202. doi: 10.1038/srep12202.
• [724] Circulating Long RNAs in Serum Extracellular Vesicles: Their Characterization and Potential Application as Biomarkers for Diagnosis of Colorectal Cancer.Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1158-66. doi: 10.1158/1055-9965.EPI-16-0006. Epub 2016 May 18.
• [725] Natural Hypoxia is Not a Limiting Factor in Evaluating the Novel Arylidene Derivative MLT-401 Against an In Vitro Colorectal Cancer Model.Cell Physiol Biochem. 2018;46(5):2082-2089. doi: 10.1159/000489448. Epub 2018 Apr 28.
• [726] Identification of key genes in colorectal cancer using random walk with restart.Mol Med Rep. 2017 Feb;15(2):867-872. doi: 10.3892/mmr.2016.6058. Epub 2016 Dec 19.
• [727] MEK5 overexpression is associated with the occurrence and development of colorectal cancer.BMC Cancer. 2016 May 9;16:302. doi: 10.1186/s12885-016-2327-9.
• [728] Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer.World J Gastroenterol. 2019 Feb 21;25(7):808-823. doi: 10.3748/wjg.v25.i7.808.
• [729] Noncanonical TGF Pathway Relieves the Blockade of IL1/TGF-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer.Clin Cancer Res. 2019 Jul 15;25(14):4466-4479. doi: 10.1158/1078-0432.CCR-18-3957. Epub 2019 Apr 12.
• [730] High-throughput RNAi screening of human kinases identifies predictors of clinical outcome in colorectal cancer patients treated with oxaliplatin.Oncotarget. 2015 Jun 30;6(18):16774-85. doi: 10.18632/oncotarget.3736.
• [731] Effect of PD98059 on chemotherapy in patients with colorectal cancer through ERK1/2 pathway.J BUON. 2019 Sep-Oct;24(5):1837-1844.
• [732] CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.Cell Death Dis. 2016 Oct 13;7(10):e2415. doi: 10.1038/cddis.2016.333.
• [733] Molecular functions of brain expressed X-linked 2 (BEX2) in malignancies.Exp Cell Res. 2019 Mar 15;376(2):221-226. doi: 10.1016/j.yexcr.2019.02.014. Epub 2019 Feb 16.
• [734] Inactivation of JNK2 as carcinogenic factor in colitis-associated and sporadic colorectal carcinogenesis.Carcinogenesis. 2017 May 1;38(5):559-569. doi: 10.1093/carcin/bgx032.
• [735] Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma.Oncogene. 2017 Nov 9;36(45):6225-6234. doi: 10.1038/onc.2017.228. Epub 2017 Jul 10.
• [736] Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.Oncogene. 2015 Feb 26;34(9):1150-9. doi: 10.1038/onc.2014.40. Epub 2014 Mar 24.
• [737] Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence.Int J Med Sci. 2019 Jun 2;16(6):813-821. doi: 10.7150/ijms.32599. eCollection 2019.
• [738] 3'-UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans.Cancer Res. 2012 Mar 15;72(6):1467-77. doi: 10.1158/0008-5472.CAN-11-3073. Epub 2012 Jan 26.
• [739] Identification of genes involved in the four stages of colorectal cancer: gene expression profiling. Mol Cell Probes. 2018 Feb;37:39-47.
• [740] Long noncoding RNA LINC02418 regulates MELK expression by acting as a ceRNA and may serve as a diagnostic marker for colorectal cancer.Cell Death Dis. 2019 Jul 29;10(8):568. doi: 10.1038/s41419-019-1804-x.
• [741] Pattern of Melanotransferrin Expression in Human Colorectal Tissues: An Immunohistochemical Study on Potential Clinical Application.Anticancer Res. 2015 Dec;35(12):6551-61.
• [742] The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.PLoS One. 2017 Jul 20;12(7):e0179979. doi: 10.1371/journal.pone.0179979. eCollection 2017.
• [743] Prognostic Correlation Between MFG-E8 Expression Level and Colorectal Cancer.Arch Med Res. 2017 Apr;48(3):270-275. doi: 10.1016/j.arcmed.2017.06.003.
• [744] Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer.Oncogene. 2013 Jan 10;32(2):234-41. doi: 10.1038/onc.2012.34. Epub 2012 Feb 20.
• [745] CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.Mol Cancer Res. 2017 Jun;15(6):696-707. doi: 10.1158/1541-7786.MCR-16-0361. Epub 2017 Feb 27.
• [746] Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling.Mol Oncol. 2018 Nov;12(11):1856-1870. doi: 10.1002/1878-0261.12384. Epub 2018 Oct 15.
• [747] Toll-Like Receptor 4 and Matrix Metalloproteases 11 and 13 as Predictors of Tumor Recurrence and Survival in Stage II Colorectal Cancer.Pathol Oncol Res. 2019 Oct;25(4):1589-1597. doi: 10.1007/s12253-019-00611-6. Epub 2019 Feb 1.
• [748] DNA methylation epigenotype and clinical features of NRAS-mutation(+) colorectal cancer.Cancer Med. 2017 May;6(5):1023-1035. doi: 10.1002/cam4.1061. Epub 2017 Apr 4.
• [749] Circular RNA hsa_circ_0053277 promotes the development of colorectal cancer by upregulating matrix metallopeptidase 14 via miR-2467-3p sequestration.J Cell Physiol. 2020 Mar;235(3):2881-2890. doi: 10.1002/jcp.29193. Epub 2019 Sep 24.
• [750] TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells.Cell Stem Cell. 2015 Jul 2;17(1):47-59. doi: 10.1016/j.stem.2015.05.016.
• [751] Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.J Hematol Oncol. 2019 Jan 25;12(1):10. doi: 10.1186/s13045-019-0699-4.
• [752] Mesothelin expression has prognostic value in stage / colorectal cancer.Virchows Arch. 2019 Mar;474(3):297-307. doi: 10.1007/s00428-018-02514-4. Epub 2019 Jan 3.
• [753] Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer.Oncotarget. 2019 Feb 12;10(13):1320-1333. doi: 10.18632/oncotarget.26663. eCollection 2019 Feb 12.
• [754] Myostatin gene inactivation prevents skeletal muscle wasting in cancer.Cancer Res. 2014 Dec 15;74(24):7344-56. doi: 10.1158/0008-5472.CAN-14-0057. Epub 2014 Oct 21.
• [755] Activation of EMT in colorectal cancer by MTDH/NF-B p65 pathway.Mol Cell Biochem. 2019 Jul;457(1-2):83-91. doi: 10.1007/s11010-019-03514-x. Epub 2019 Mar 1.
• [756] Frameshift mutations of MUC15 gene in gastric and its regional heterogeneity in gastric and colorectal cancers.Pathol Oncol Res. 2015 Jul;21(3):713-8. doi: 10.1007/s12253-014-9878-3. Epub 2015 Jan 9.
• [757] Novel Vaccine Targeting Colonic Adenoma: a Pre-clinical Model.J Gastrointest Surg. 2019 Mar;23(3):626-633. doi: 10.1007/s11605-018-4060-y. Epub 2019 Jan 8.
• [758] Digital polymerase chain reaction for detecting c-MYC copy number gain in tissue and cell-free plasma samples of colorectal cancer patients.Sci Rep. 2019 Feb 7;9(1):1611. doi: 10.1038/s41598-018-38415-4.
• [759] Non-coding RNA MFI2-AS1 promotes colorectal cancer cell proliferation, migration and invasion through miR-574-5p/MYCBP axis.Cell Prolif. 2019 Jul;52(4):e12632. doi: 10.1111/cpr.12632. Epub 2019 May 16.
• [760] Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors.Sci Rep. 2017 Apr 4;7(1):641. doi: 10.1038/s41598-017-00219-3.
• [761] MyD88 mediates colorectal cancer cell proliferation, migration and invasion via NFB/AP? signaling pathway.Int J Mol Med. 2020 Jan;45(1):131-140. doi: 10.3892/ijmm.2019.4390. Epub 2019 Oct 31.
• [762] The elevated NLR, PLR and PLT may predict the prognosis of patients with colorectal cancer: a systematic review and meta-analysis.Oncotarget. 2017 Jun 19;8(40):68837-68846. doi: 10.18632/oncotarget.18575. eCollection 2017 Sep 15.
• [763] Overexpression of NAC1 confers drug resistance via HOXA9 in colorectal carcinoma cells.Mol Med Rep. 2017 Sep;16(3):3194-3200. doi: 10.3892/mmr.2017.6986. Epub 2017 Jul 14.
• [764] Increased nicotinamide adenine dinucleotide pool promotes colon cancer progression by suppressing reactive oxygen species level.Cancer Sci. 2019 Feb;110(2):629-638. doi: 10.1111/cas.13886. Epub 2018 Dec 27.
• [765] NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer.Front Oncol. 2019 Aug 6;9:736. doi: 10.3389/fonc.2019.00736. eCollection 2019.
• [766] Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.Cell Signal. 2017 Aug;36:67-78. doi: 10.1016/j.cellsig.2017.04.020. Epub 2017 Apr 25.
• [767] Correlating Changes in the Epithelial Gland Tissue With Advancing Colorectal Cancer Histologic Grade, Using IHC Stained for AIB1 Expression Biopsy Material.Appl Immunohistochem Mol Morphol. 2019 Nov/Dec;27(10):749-757. doi: 10.1097/PAI.0000000000000691.
• [768] NKp46-expressing human gut-resident intraepithelial V1 T cell subpopulation exhibits high antitumor activity against colorectal cancer.JCI Insight. 2019 Dec 19;4(24):e125884. doi: 10.1172/jci.insight.125884.
• [769] GRIM-19 repressed hypoxia-induced invasion and EMT of colorectal cancer by repressing autophagy through inactivation of STAT3/HIF-1 signaling axis.J Cell Physiol. 2019 Aug;234(8):12800-12808. doi: 10.1002/jcp.27914. Epub 2018 Dec 7.
• [770] Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.Oncol Lett. 2019 Aug;18(2):1163-1170. doi: 10.3892/ol.2019.10417. Epub 2019 May 30.
• [771] N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21.J Exp Clin Cancer Res. 2019 Dec 12;38(1):490. doi: 10.1186/s13046-019-1476-5.
• [772] Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.J Natl Cancer Inst. 2016 Oct 22;109(2):djw209. doi: 10.1093/jnci/djw209. Print 2017 Feb.
• [773] NEDD9 promotes invasion and migration of colorectal cancer cell line HCT116 via JNK/EMT.Oncol Lett. 2019 Oct;18(4):4022-4029. doi: 10.3892/ol.2019.10756. Epub 2019 Aug 16.
• [774] FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo.BMC Cancer. 2019 Sep 13;19(1):918. doi: 10.1186/s12885-019-6028-z.
• [775] Effect of once-only flexible sigmoidoscopy screening on the outcomes of subsequent faecal occult blood test screening.J Med Screen. 2019 Mar;26(1):11-18. doi: 10.1177/0969141318785654. Epub 2018 Oct 3.
• [776] Whole Exome Sequencing of Ulcerative Colitis-associated Colorectal Cancer Based on Novel Somatic Mutations Identified in Chinese Patients.Inflamm Bowel Dis. 2019 Jul 17;25(8):1293-1301. doi: 10.1093/ibd/izz020.
• [777] NPC-26 kills human colorectal cancer cells via activating AMPK signaling.Oncotarget. 2017 Mar 14;8(11):18312-18321. doi: 10.18632/oncotarget.15436.
• [778] Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components.Oncotarget. 2015 Oct 20;6(32):33456-69. doi: 10.18632/oncotarget.5587.
• [779] miR-195-5p/NOTCH2-mediated EMT modulates IL-4 secretion in colorectal cancer to affect M2-like TAM polarization.J Hematol Oncol. 2019 Feb 26;12(1):20. doi: 10.1186/s13045-019-0708-7.
• [780] Prognostic role of nucleophosmin in colorectal carcinomas.Asian Pac J Cancer Prev. 2014;15(5):2021-6. doi: 10.7314/apjcp.2014.15.5.2021.
• [781] NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/-catenin pathway via FZD6.Cell Death Dis. 2019 Mar 4;10(3):217. doi: 10.1038/s41419-019-1467-7.
• [782] RING-Finger Protein 6 Amplification Activates JAK/STAT3 Pathway by Modifying SHP-1 Ubiquitylation and Associates with Poor Outcome in Colorectal Cancer.Clin Cancer Res. 2018 Mar 15;24(6):1473-1485. doi: 10.1158/1078-0432.CCR-17-2133. Epub 2017 Dec 29.
• [783] Association between nucleotide excision repair gene polymorphism and colorectal cancer risk.J Clin Lab Anal. 2019 Oct;33(8):e22956. doi: 10.1002/jcla.22956. Epub 2019 Sep 30.
• [784] LXR-mediated downregulation of EGFR suppress colorectal cancer cell proliferation.J Cell Biochem. 2019 Oct;120(10):17391-17404. doi: 10.1002/jcb.29003. Epub 2019 May 19.
• [785] Combination Therapy with EpCAM-CAR-NK-92 Cells and Regorafenib against Human Colorectal Cancer Models.J Immunol Res. 2018 Oct 15;2018:4263520. doi: 10.1155/2018/4263520. eCollection 2018.
• [786] The decrease of mineralcorticoid receptor drives angiogenic pathways in colorectal cancer.PLoS One. 2013;8(3):e59410. doi: 10.1371/journal.pone.0059410. Epub 2013 Mar 28.
• [787] Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells.Int J Oncol. 2017 Jun;50(6):2200-2206. doi: 10.3892/ijo.2017.3990. Epub 2017 May 9.
• [788] Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers.Int J Oncol. 2014 Jan;44(1):69-77. doi: 10.3892/ijo.2013.2177. Epub 2013 Nov 15.
• [789] Inhibition of Polyamine Biosynthesis Reverses Ca(2+) Channel Remodeling in Colon Cancer Cells.Cancers (Basel). 2019 Jan 13;11(1):83. doi: 10.3390/cancers11010083.
• [790] Frameshift mutations of OGDH, PPAT and PCCA genes in gastric and colorectal cancers.Neoplasma. 2016;63(5):681-6. doi: 10.4149/neo_2016_504.
• [791] Olfactomedin-4 in digestive diseases: A mini-review.World J Gastroenterol. 2018 May 7;24(17):1881-1887. doi: 10.3748/wjg.v24.i17.1881.
• [792] Targeting LOX-1 Inhibits Colorectal Cancer Metastasis in an Animal Model.Front Oncol. 2019 Sep 19;9:927. doi: 10.3389/fonc.2019.00927. eCollection 2019.
• [793] Diagnostic and prognostic role of cell-free DNA testing for colorectal cancer patients.Int J Cancer. 2017 Apr 15;140(8):1888-1898. doi: 10.1002/ijc.30565. Epub 2017 Jan 5.
• [794] Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.Sci Rep. 2018 Aug 14;8(1):12096. doi: 10.1038/s41598-018-30591-7.
• [795] The role of P2X7 receptor in prognosis and metastasis of colorectal cancer.Adv Med Sci. 2019 Sep;64(2):388-394. doi: 10.1016/j.advms.2019.05.002. Epub 2019 Jul 2.
• [796] The G protein-coupled P2Y?receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1539-1551. doi: 10.1016/j.bbadis.2018.02.008. Epub 2018 Feb 14.
• [797] PABPC1L depletion inhibits proliferation and migration via blockage of AKT pathway in human colorectal cancer cells.Oncol Lett. 2019 Mar;17(3):3439-3445. doi: 10.3892/ol.2019.9999. Epub 2019 Jan 31.
• [798] Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.
• [799] Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer.Nat Commun. 2018 Aug 27;9(1):3473. doi: 10.1038/s41467-018-05935-6.
• [800] Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway.Cancer Manag Res. 2018 Dec 20;11:95-105. doi: 10.2147/CMAR.S169476. eCollection 2019.
• [801] The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.J Pathol. 2018 Jan;244(1):36-48. doi: 10.1002/path.4986. Epub 2017 Nov 27.
• [802] Strong decrease in biotin content may correlate with metabolic alterations in colorectal adenocarcinoma.Int J Cancer. 1997 Sep 4;72(5):768-75. doi: 10.1002/(sici)1097-0215(19970904)72:5<768::aid-ijc11>3.0.co;2-5.
• [803] A subset of patients with MSS/MSI-low-colorectal cancer showed increased CD8(+) TILs together with up-regulated IFN-.Oncol Lett. 2019 Dec;18(6):5977-5985. doi: 10.3892/ol.2019.10953. Epub 2019 Oct 2.
• [804] Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and -catenin-dependent TCF transcriptional activity.Oncogene. 2015 Mar 19;34(12):1499-509. doi: 10.1038/onc.2014.94. Epub 2014 Apr 7.
• [805] Post-transcriptional regulation of the tumor suppressor miR-139-5p and a network of miR-139-5p-mediated mRNA interactions in colorectal cancer.FEBS J. 2014 Aug;281(16):3609-24. doi: 10.1111/febs.12880. Epub 2014 Jul 15.
• [806] Human UTP14a promotes angiogenesis through upregulating PDGFA expression in colorectal cancer.Biochem Biophys Res Commun. 2019 May 14;512(4):871-876. doi: 10.1016/j.bbrc.2019.03.142. Epub 2019 Mar 28.
• [807] Possible Role and Therapeutic Target of PDGF-D Signalling in Colorectal Cancer.Cancer Invest. 2019;37(2):99-112. doi: 10.1080/07357907.2019.1576191. Epub 2019 Mar 5.
• [808] The double inhibition of PDK1 and STAT3-Y705 prevents liver metastasis in colorectal cancer.Sci Rep. 2019 Sep 10;9(1):12973. doi: 10.1038/s41598-019-49480-8.
• [809] Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies.Oncol Lett. 2018 Jan;15(1):1236-1240. doi: 10.3892/ol.2017.7392. Epub 2017 Nov 10.
• [810] An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.PLoS Genet. 2013;9(1):e1003254. doi: 10.1371/journal.pgen.1003254. Epub 2013 Jan 31.
• [811] CXCL5 induces tumor angiogenesis via enhancing the expression of FOXD1 mediated by the AKT/NF-B pathway in colorectal cancer.Cell Death Dis. 2019 Feb 21;10(3):178. doi: 10.1038/s41419-019-1431-6.
• [812] Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer.Int J Oncol. 2016 Jan;48(1):215-24. doi: 10.3892/ijo.2015.3225. Epub 2015 Nov 2.
• [813] Using serum placenta growth factor could improve the sensitivity of colorectal cancer screening in fecal occult blood negative population: A multicenter with independent cohort validation study.Cancer Med. 2019 Jul;8(7):3583-3591. doi: 10.1002/cam4.2216. Epub 2019 May 7.
• [814] Prognostic value of estrogen receptor- and progesterone receptor in curatively resected colorectal cancer: a retrospective analysis with independent validations.BMC Cancer. 2019 Oct 7;19(1):933. doi: 10.1186/s12885-019-5918-4.
• [815] Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.Oncotarget. 2017 Jul 19;8(44):76340-76356. doi: 10.18632/oncotarget.19394. eCollection 2017 Sep 29.
• [816] Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 invitro.Mol Med Rep. 2017 Oct;16(4):4437-4444. doi: 10.3892/mmr.2017.7130. Epub 2017 Aug 1.
• [817] Matrix Metalloproteinase-2 and -9, Lactate, and Malate Dehydrogenase and Lipid Peroxides in Sera of Patients with Colorectal Carcinoma.Folia Biol (Praha). 2017;63(5-6):190-196.
• [818] Cholesterol regulates cell proliferation and apoptosis of colorectal cancer by modulating miR-33a-PIM3 pathway.Biochem Biophys Res Commun. 2019 Apr 9;511(3):685-692. doi: 10.1016/j.bbrc.2019.02.123. Epub 2019 Feb 28.
• [819] Pin2/TRF1binding proteinX1 inhibits colorectal cancer cell migration and invasion invitro and metastasis invivo via the nuclear factorB signaling pathway.Oncol Rep. 2018 Sep;40(3):1533-1544. doi: 10.3892/or.2018.6570. Epub 2018 Jul 13.
• [820] Oral Administration of Liposome-Apatinib and Locally Delivery of Docetaxel/MPEG-PCL by Fibrin Glue Synergistically Improve Therapeutic Effect in Colorectal Cancer.J Biomed Nanotechnol. 2018 Dec 1;14(12):2077-2091. doi: 10.1166/jbn.2018.2651.
• [821] PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis.J Clin Invest. 2016 Feb;126(2):681-94. doi: 10.1172/JCI83587. Epub 2016 Jan 19.
• [822] Loss of PKM2 in Lgr5(+) intestinal stem cells promotes colitis-associated colorectal cancer.Sci Rep. 2019 Apr 17;9(1):6212. doi: 10.1038/s41598-019-42707-8.
• [823] Polymorphisms in arachidonic acid metabolism-related genes and the risk and prognosis of colorectal cancer.Fam Cancer. 2013 Dec;12(4):755-65. doi: 10.1007/s10689-013-9659-2.
• [824] Targeting cytosolic phospholipase A2 in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.Oncotarget. 2014 Dec 15;5(23):12304-16. doi: 10.18632/oncotarget.2639.
• [825] Prognostic significance of PLA2G4C gene polymorphism in patients with stage II colorectal cancer.Acta Oncol. 2016;55(4):474-9. doi: 10.3109/0284186X.2015.1073350. Epub 2015 Sep 12.
• [826] Phospholipase C1 links inflammation and tumorigenesis in colitis-associated cancer.Oncotarget. 2017 Dec 19;9(5):5752-5763. doi: 10.18632/oncotarget.23430. eCollection 2018 Jan 19.
• [827] Phospholipase D1 Inhibition Linked to Upregulation of ICAT Blocks Colorectal Cancer Growth Hyperactivated by Wnt/-Catenin and PI3K/Akt Signaling.Clin Cancer Res. 2017 Dec 1;23(23):7340-7350. doi: 10.1158/1078-0432.CCR-17-0749. Epub 2017 Sep 22.
• [828] Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells.Exp Mol Med. 2014 Dec 5;46(12):e124. doi: 10.1038/emm.2014.74.
• [829] Role of bile acids in colon carcinogenesis.World J Clin Cases. 2018 Nov 6;6(13):577-588. doi: 10.12998/wjcc.v6.i13.577.
• [830] Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling.Neoplasia. 2018 Mar;20(3):244-255. doi: 10.1016/j.neo.2018.01.004. Epub 2018 Feb 12.
• [831] PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2.Biochem Cell Biol. 2020 Jun;98(3):386-395. doi: 10.1139/bcb-2019-0256. Epub 2019 Nov 19.
• [832] Mismatch repair protein expression in patients with stage II and III sporadic colorectal cancer.Oncol Lett. 2018 May;15(5):8053-8061. doi: 10.3892/ol.2018.8337. Epub 2018 Mar 23.
• [833] Periostin attenuates tumor growth by inducing apoptosis in colitis-related colorectal cancer.Oncotarget. 2018 Apr 13;9(28):20008-20017. doi: 10.18632/oncotarget.25026. eCollection 2018 Apr 13.
• [834] Expression and role of nuclear receptor coregulators in colorectal cancer.World J Gastroenterol. 2017 Jul 7;23(25):4480-4490. doi: 10.3748/wjg.v23.i25.4480.
• [835] Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies.Inflamm Bowel Dis. 2014 Jul;20(7):1147-56. doi: 10.1097/MIB.0000000000000067.
• [836] Cyclophilin B induces chemoresistance by degrading wild-type p53 via interaction with MDM2 in colorectal cancer.J Pathol. 2018 Sep;246(1):115-126. doi: 10.1002/path.5107. Epub 2018 Aug 6.
• [837] Significance of positive and inhibitory regulators in the TGF- signaling pathway in colorectal cancers.Hum Pathol. 2017 Aug;66:34-39. doi: 10.1016/j.humpath.2017.05.021. Epub 2017 Jun 7.
• [838] Wip1 cooperates with KPNA2 to modulate the cell proliferation and migration of colorectal cancer via a p53-dependent manner.J Cell Biochem. 2019 Sep;120(9):15709-15718. doi: 10.1002/jcb.28840. Epub 2019 May 24.
• [839] USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.EBioMedicine. 2019 Oct;48:236-247. doi: 10.1016/j.ebiom.2019.08.061. Epub 2019 Sep 11.
• [840] Association between PPP2CA expression and colorectal cancer prognosis tumor marker prognostic study.Int J Surg. 2018 Nov;59:80-89. doi: 10.1016/j.ijsu.2018.09.020. Epub 2018 Oct 5.
• [841] Characterization of novel low passage primary and metastatic colorectal cancer cell lines.Oncotarget. 2016 Mar 22;7(12):14499-509. doi: 10.18632/oncotarget.7391.
• [842] Enterohormonal disturbances in colorectal cancer patients.Neoplasma. 2017;64(3):421-429. doi: 10.4149/neo_2017_313.
• [843] Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells.Biomed Pharmacother. 2020 Jan;121:109665. doi: 10.1016/j.biopha.2019.109665. Epub 2019 Nov 22.
• [844] Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids. Int J Cancer. 1995 Mar 29;61(1):35-9. doi: 10.1002/ijc.2910610107.
• [845] Protein kinase d as a potential chemotherapeutic target for colorectal cancer. Mol Cancer Ther. 2014 May;13(5):1130-41. doi: 10.1158/1535-7163.MCT-13-0880. Epub 2014 Mar 14.
• [846] Polymorphisms of XRCC3 and XRCC7 and Colorectal Cancer Risk in Khorasan Razavi Province, Iran.Asian Pac J Cancer Prev. 2019 Jul 1;20(7):2153-2158. doi: 10.31557/APJCP.2019.20.7.2153.
• [847] EGFR and Prion protein promote signaling via FOXO3a-KLF5 resulting in clinical resistance to platinum agents in colorectal cancer.Mol Oncol. 2019 Apr;13(4):725-737. doi: 10.1002/1878-0261.12411. Epub 2019 Feb 8.
• [848] Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) and its receptor PROKR2 are associated to human colorectal cancer progression and peritoneal carcinomatosis.Cancer Biomark. 2018 Feb 6;21(2):345-354. doi: 10.3233/CBM-170499.
• [849] MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.Mol Oncol. 2018 Feb;12(2):224-238. doi: 10.1002/1878-0261.12160. Epub 2017 Dec 27.
• [850] Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice.Oncotarget. 2017 Feb 7;8(31):50873-50888. doi: 10.18632/oncotarget.15141. eCollection 2017 Aug 1.
• [851] Gankyrin Contributes to Tumorigenesis and Chemoresistance in Sporadic Colorectal Cancer.Digestion. 2019;100(3):192-200. doi: 10.1159/000494969. Epub 2018 Dec 4.
• [852] The RNA-Binding Protein HuR Confers Oxaliplatin Resistance of Colorectal Cancer By Upregulating CDC6.Mol Cancer Ther. 2019 Jul;18(7):1243-1254. doi: 10.1158/1535-7163.MCT-18-0945. Epub 2019 May 7.
• [853] PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31. doi: 10.1158/1055-9965.EPI-09-1154. Epub 2010 Mar 3.
• [854] Interaction between laminin-52 and integrin 1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins.Oncogene. 2020 Feb;39(7):1527-1542. doi: 10.1038/s41388-019-1082-1. Epub 2019 Nov 1.
• [855] miR?05?p/PTK7 axis is involved in the proliferation, migration and invasion of colorectal cancer cells.Mol Med Rep. 2018 May;17(5):6253-6260. doi: 10.3892/mmr.2018.8650. Epub 2018 Feb 28.
• [856] Interaction with tumorassociated macrophages promotes PRL?induced invasion of colorectal cancer cells via MAPK pathwayinduced EMT and NFB signalinginduced angiogenesis.Oncol Rep. 2019 May;41(5):2790-2802. doi: 10.3892/or.2019.7049. Epub 2019 Mar 7.
• [857] Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.Sci Rep. 2016 Oct 18;6:35308. doi: 10.1038/srep35308.
• [858] Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14.Oncogene. 2013 Apr 18;32(16):2087-95. doi: 10.1038/onc.2012.220. Epub 2012 Jun 18.
• [859] PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition.Cell Death Dis. 2019 Apr 30;10(5):352. doi: 10.1038/s41419-019-1554-9.
• [860] PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC.Oncotarget. 2019 Nov 26;10(63):6768-6780. doi: 10.18632/oncotarget.27335. eCollection 2019 Nov 26.
• [861] High PTPRQ Expression and Its Relationship to Expression of PTPRZ1 and the Presence of KRAS Mutations in Colorectal Cancer Tissues.Anticancer Res. 2016 Feb;36(2):677-81.
• [862] Changes in plasma levels of cholecystokinin, neurotensin, VIP and PYY in gastric and colorectal cancer - Preliminary results.Peptides. 2019 Dec;122:170148. doi: 10.1016/j.peptides.2019.170148. Epub 2019 Sep 18.
• [863] LncRNA-UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p.Sci Rep. 2016 Apr 5;6:23892. doi: 10.1038/srep23892.
• [864] Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas.Cell Death Dis. 2019 Feb 13;10(2):143. doi: 10.1038/s41419-019-1402-y.
• [865] TNF Signaling through RIP1 Kinase Enhances SN38-Induced Death in Colon Adenocarcinoma.Mol Cancer Res. 2017 Apr;15(4):395-404. doi: 10.1158/1541-7786.MCR-16-0329. Epub 2017 Jan 13.
• [866] Epigenetic signatures of familial cancer are characteristic of tumor type and family category.Cancer Res. 2008 Jun 15;68(12):4597-605. doi: 10.1158/0008-5472.CAN-07-6645.
• [867] Oncogenic retinoic acid receptor knockdown reverses multi-drug resistance of human colorectal cancer via Wnt/-catenin pathway.Cell Cycle. 2017 Apr 3;16(7):685-692. doi: 10.1080/15384101.2017.1295180. Epub 2017 Mar 8.
• [868] RBCK1 contributes to chemoresistance and stemness in colorectal cancer (CRC).Biomed Pharmacother. 2019 Oct;118:109250. doi: 10.1016/j.biopha.2019.109250. Epub 2019 Aug 13.
• [869] Overcoming stemness and chemoresistance in colorectal cancer through miR-195-5p-modulated inhibition of notch signaling.Int J Biol Macromol. 2018 Oct 1;117:445-453. doi: 10.1016/j.ijbiomac.2018.05.151. Epub 2018 May 28.
• [870] Reduced RCE1 expression predicts poor prognosis of colorectal carcinoma.BMC Cancer. 2017 Jun 14;17(1):414. doi: 10.1186/s12885-017-3393-3.
• [871] Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk.Oncotarget. 2016 Jan 26;7(4):3921-33. doi: 10.18632/oncotarget.6473.
• [872] Energy restriction at young age, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk in the Netherlands Cohort Study.Int J Cancer. 2017 Jan 15;140(2):272-284. doi: 10.1002/ijc.30439. Epub 2016 Oct 18.
• [873] The Critical Role of Dysregulated RhoB Signaling Pathway in Radioresistance of Colorectal Cancer.Int J Radiat Oncol Biol Phys. 2019 Aug 1;104(5):1153-1164. doi: 10.1016/j.ijrobp.2019.04.021. Epub 2019 Apr 27.
• [874] Update on genetic predisposition to colorectal cancer and polyposis.Mol Aspects Med. 2019 Oct;69:10-26. doi: 10.1016/j.mam.2019.03.001. Epub 2019 Mar 18.
• [875] Identification of RING-box 2 as a potential target for combating colorectal cancer growth and metastasis.Am J Cancer Res. 2017 Jun 1;7(6):1238-1251. eCollection 2017.
• [876] RNA-seq reveals determinants for irinotecan sensitivity/resistance in colorectal cancer cell lines.Int J Clin Exp Pathol. 2014 Apr 15;7(5):2729-36. eCollection 2014.
• [877] Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer.Int J Med Sci. 2015 Jun 2;12(6):458-67. doi: 10.7150/ijms.11808. eCollection 2015.
• [878] MiR-199a-5p Inhibits the Growth and Metastasis of Colorectal Cancer Cells by Targeting ROCK1.Technol Cancer Res Treat. 2018 Jan 1;17:1533034618775509. doi: 10.1177/1533034618775509.
• [879] ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.Gynecol Oncol. 2018 Mar;148(3):576-584. doi: 10.1016/j.ygyno.2018.01.025. Epub 2018 Feb 1.
• [880] Retinoic Acid Receptor-Related Orphan Receptors: Critical Roles in Tumorigenesis.Front Immunol. 2018 May 31;9:1187. doi: 10.3389/fimmu.2018.01187. eCollection 2018.
• [881] The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress.Cell Death Dis. 2019 Aug 8;10(8):600. doi: 10.1038/s41419-019-1824-6.
• [882] Primate-specific miR-944 activates p53-dependent tumor suppression in human colorectal cancers.Cancer Lett. 2019 Jan;440-441:168-179. doi: 10.1016/j.canlet.2018.10.029. Epub 2018 Oct 27.
• [883] High Adherence to Surveillance Guidelines in Inflammatory Bowel Disease Patients Results in Low Colorectal Cancer and Dysplasia Rates, While Rates of Dysplasia are Low Before the Suggested Onset of Surveillance.J Crohns Colitis. 2019 Sep 27;13(10):1343-1350. doi: 10.1093/ecco-jcc/jjz066.
• [884] Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors.PLoS One. 2015 Nov 10;10(11):e0142487. doi: 10.1371/journal.pone.0142487. eCollection 2015.
• [885] Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers.Hum Pathol. 2015 May;46(5):753-60. doi: 10.1016/j.humpath.2015.01.017. Epub 2015 Feb 12.
• [886] Effect of RSK4 on biological characteristics of colorectal cancer.World J Surg Oncol. 2018 Dec 22;16(1):240. doi: 10.1186/s12957-018-1474-7.
• [887] Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer.Oncol Lett. 2017 Dec;14(6):7323-7331. doi: 10.3892/ol.2017.7085. Epub 2017 Sep 27.
• [888] Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.BMC Cancer. 2018 May 29;18(1):602. doi: 10.1186/s12885-018-4531-2.
• [889] EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.Histopathology. 2019 Aug;75(2):266-273. doi: 10.1111/his.13867. Epub 2019 Jun 20.
• [890] RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.Gut. 2017 Jun;66(6):1095-1105. doi: 10.1136/gutjnl-2016-311606. Epub 2016 Aug 10.
• [891] Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.Chem Commun (Camb). 2017 Jun 29;53(53):7234-7237. doi: 10.1039/c7cc01480e.
• [892] Antitumor activity of iNGR-GRIM-19 in colorectal cancer.Jpn J Clin Oncol. 2017 Sep 1;47(9):795-808. doi: 10.1093/jjco/hyx090.
• [893] Evaluation of MGP gene expression in colorectal cancer.Gene. 2020 Jan 10;723:144120. doi: 10.1016/j.gene.2019.144120. Epub 2019 Oct 4.
• [894] Suppression of retinoid X receptor alpha and aberrant -catenin expression significantly associates with progression of colorectal carcinoma.Eur J Cancer. 2011 Sep;47(13):2060-7. doi: 10.1016/j.ejca.2011.04.010. Epub 2011 May 9.
• [895] An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal Cancer.Cancers (Basel). 2019 Oct 2;11(10):1482. doi: 10.3390/cancers11101482.
• [896] S100A6 stimulates proliferation and migration of colorectal carcinoma cells through activation of the MAPK pathways.Int J Oncol. 2014 Mar;44(3):781-90. doi: 10.3892/ijo.2013.2231. Epub 2013 Dec 30.
• [897] Granulocytic Myeloid-Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9.Adv Sci (Weinh). 2019 Jul 22;6(18):1901278. doi: 10.1002/advs.201901278. eCollection 2019 Sep 18.
• [898] The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1-STAT3 signaling pathway.Cell Death Dis. 2019 Sep 18;10(10):693. doi: 10.1038/s41419-019-1922-5.
• [899] SATB1 Expression of Colorectal Adenomatous Polyps is Higher than that of Colorectal Carcinomas.Appl Immunohistochem Mol Morphol. 2020 Aug;28(7):532-537. doi: 10.1097/PAI.0000000000000791.
• [900] Trichothecin inhibits invasion and metastasis of colon carcinoma associating with SCD-1-mediated metabolite alteration.Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb;1865(2):158540. doi: 10.1016/j.bbalip.2019.158540. Epub 2019 Oct 31.
• [901] Nasoethmoidal Intestinal-Type Adenocarcinoma Treated with Cetuximab: Role of Liquid Biopsy and BEAMing in Predicting Response to Anti-Epidermal Growth Factor Receptor Therapy.Oncologist. 2019 Mar;24(3):293-300. doi: 10.1634/theoncologist.2018-0387. Epub 2019 Jan 2.
• [902] Decreased expression of SCUBE2 is associated with progression and prognosis in colorectal cancer. Oncol Rep. 2015 Apr;33(4):1956-64.
• [903] Syndecan-1 suppresses cell growth and migration via blocking JAK1/STAT3 and Ras/Raf/MEK/ERK pathways in human colorectal carcinoma cells.BMC Cancer. 2019 Nov 29;19(1):1160. doi: 10.1186/s12885-019-6381-y.
• [904] Syndecan-2 in colorectal cancer plays oncogenic role via epithelial-mesenchymal transition and MAPK pathway.Biomed Pharmacother. 2020 Jan;121:109630. doi: 10.1016/j.biopha.2019.109630. Epub 2019 Nov 7.
• [905] HOTAIR/miR-326/FUT6 axis facilitates colorectal cancer progression through regulating fucosylation of CD44 via PI3K/AKT/mTOR pathway.Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):750-760. doi: 10.1016/j.bbamcr.2019.02.004. Epub 2019 Feb 8.
• [906] Evaluation of Alpha 1-Antitrypsin for the Early Diagnosis of Colorectal Cancer.Pathol Oncol Res. 2020 Apr;26(2):1165-1173. doi: 10.1007/s12253-019-00679-0. Epub 2019 Jun 10.
• [907] SerpinB3 upregulates the Cyclooxygenase-2 / -Catenin positive loop in colorectal cancer.Oncotarget. 2017 Feb 28;8(9):15732-15743. doi: 10.18632/oncotarget.14997.
• [908] Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015.
• [909] Proteomics analysis of differential protein expression identifies heat shock protein 47 as a predictive marker for lymph node metastasis in patients with colorectal cancer.Int J Cancer. 2017 Mar 15;140(6):1425-1435. doi: 10.1002/ijc.30557.
• [910] Secretome profiling of heterotypic spheroids suggests a role of fibroblasts in HIF-1 pathway modulation and colorectal cancer photodynamic resistance.Cell Oncol (Dordr). 2019 Apr;42(2):173-196. doi: 10.1007/s13402-018-00418-8. Epub 2019 Feb 12.
• [911] Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.Carcinogenesis. 2010 Aug;31(8):1381-6. doi: 10.1093/carcin/bgq082. Epub 2010 Apr 19.
• [912] Serum- and Glucocorticoid-induced Kinase Sgk1 Directly Promotes the Differentiation of Colorectal Cancer Cells and Restrains Metastasis.Clin Cancer Res. 2019 Jan 15;25(2):629-640. doi: 10.1158/1078-0432.CCR-18-1033. Epub 2018 Oct 15.
• [913] Frameshift mutations of chromosome cohesion-related genes SGOL1 and PDS5B in gastric and colorectal cancers with high microsatellite instability.Hum Pathol. 2013 Oct;44(10):2234-40. doi: 10.1016/j.humpath.2013.04.017. Epub 2013 Jul 12.
• [914] LNK protein: Low expression in human colorectal carcinoma and relationship with tumor invasion.Biomed Pharmacother. 2020 Jan;121:109467. doi: 10.1016/j.biopha.2019.109467. Epub 2019 Nov 6.
• [915] Sonic Hedgehog Protein is Frequently Up-Regulated in Pancreatic Cancer Compared to Colorectal Cancer. Pathol Oncol Res. 2018 Dec 11.
• [916] Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions.Cancer Res. 2019 Mar 15;79(6):1047-1053. doi: 10.1158/0008-5472.CAN-18-3126. Epub 2019 Jan 14.
• [917] Evodiamine inhibits migration and invasion by Sirt1-mediated post-translational modulations in colorectal cancer.Anticancer Drugs. 2019 Jul;30(6):611-617. doi: 10.1097/CAD.0000000000000760.
• [918] Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model. J Med Chem. 2019 Apr 25; 62(8):4131-4141.
• [919] Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis.Exp Mol Med. 2018 Apr 13;50(4):1-11. doi: 10.1038/s12276-017-0002-0.
• [920] SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer.Mol Oncol. 2019 Feb;13(2):358-375. doi: 10.1002/1878-0261.12408. Epub 2018 Dec 3.
• [921] Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth.EBioMedicine. 2020 Jan;51:102570. doi: 10.1016/j.ebiom.2019.11.031. Epub 2019 Dec 2.
• [922] Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.Cell Metab. 2016 Sep 13;24(3):447-461. doi: 10.1016/j.cmet.2016.07.015. Epub 2016 Aug 18.
• [923] Analysis of the clinical significance of DCLK1(+) colorectal cancer using novel monoclonal antibodies against DCLK1.Onco Targets Ther. 2018 Aug 21;11:5047-5057. doi: 10.2147/OTT.S169928. eCollection 2018.
• [924] Overexpression of SLC12A5 is associated with tumor progression and poor survival in ovarian carcinoma.Int J Gynecol Cancer. 2019 Oct;29(8):1280-1284. doi: 10.1136/ijgc-2019-000229.
• [925] The prognostic significance of the expression of monocarboxylate transporter 4 in patients with right- or left-sided colorectal cancer.Asia Pac J Clin Oncol. 2019 Apr;15(2):e49-e55. doi: 10.1111/ajco.13077. Epub 2018 Sep 30.
• [926] The density of Tbet+ tumor-infiltrating T lymphocytes reflects an effective and druggable preexisting adaptive antitumor immune response in colorectal cancer, irrespective of the microsatellite status.Oncoimmunology. 2019 Jan 19;8(4):e1562834. doi: 10.1080/2162402X.2018.1562834. eCollection 2019.
• [927] The glutamate transport inhibitor DL-Threo--Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.BMC Cancer. 2015 May 16;15:411. doi: 10.1186/s12885-015-1405-8.
• [928] CD44-SLC1A2 fusion transcripts in primary colorectal cancer.Pathol Oncol Res. 2015 Jul;21(3):759-64. doi: 10.1007/s12253-014-9887-2. Epub 2015 Jan 10.
• [929] Inhibition of SLC1A5 sensitizes colorectal cancer to cetuximab.Int J Cancer. 2018 Jun 15;142(12):2578-2588. doi: 10.1002/ijc.31274. Epub 2018 Feb 9.
• [930] Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses.Biomark Res. 2018 Jun 13;6:17. doi: 10.1186/s40364-018-0133-z. eCollection 2018.
• [931] Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters. Cancer Res. 2010 Jul 15;70(14):5931-41.
• [932] Hormetic dose response to (L)-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression.Sci Rep. 2018 Jul 27;8(1):11372. doi: 10.1038/s41598-018-29386-7.
• [933] Therapeutic potential of adenovirus-mediated TFF2-CTP-Flag peptide for treatment of colorectal cancer.Cancer Gene Ther. 2019 Feb;26(1-2):48-57. doi: 10.1038/s41417-018-0036-z. Epub 2018 Jul 25.
• [934] A signature for induced pluripotent stem cell-associated genes in colorectal cancer.Med Oncol. 2013 Mar;30(1):426. doi: 10.1007/s12032-012-0426-2. Epub 2013 Jan 11.
• [935] Inhibition of histone deacetylase 7 reverses concentrative nucleoside transporter 2 repression in colorectal cancer by up-regulating histone acetylation state. Br J Pharmacol. 2018 Nov;175(22):4209-4217.
• [936] Differential expression of hENT1 and hENT2 in colon cancer cell lines.Genet Mol Res. 2017 Feb 16;16(1). doi: 10.4238/gmr16019549.
• [937] Suppressive effects of the sodiumglucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice.Oncol Rep. 2019 Dec;42(6):2797-2805. doi: 10.3892/or.2019.7357. Epub 2019 Oct 7.
• [938] EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases.Oncotarget. 2017 Sep 16;8(54):92195-92208. doi: 10.18632/oncotarget.21028. eCollection 2017 Nov 3.
• [939] Lactate calcium salt affects the viability of colorectal cancer cells via betaine homeostasis.Life Sci. 2016 Feb 15;147:71-6. doi: 10.1016/j.lfs.2016.01.030. Epub 2016 Jan 20.
• [940] Susceptibility and severity of cancer-related fatigue in colorectal cancer patients is associated with SLC6A4 gene single nucleotide polymorphism rs25531 A>G genotype.Eur J Oncol Nurs. 2018 Apr;33:97-101. doi: 10.1016/j.ejon.2018.02.003. Epub 2018 Mar 1.
• [941] Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression.J Hematol Oncol. 2018 Jul 3;11(1):89. doi: 10.1186/s13045-018-0632-2.
• [942] Influence of the functional polymorphisms in the organic anion transporting polypeptide 1B1 in the susceptibility to colorectal cancer.Genet Test Mol Biomarkers. 2013 Mar;17(3):214-8. doi: 10.1089/gtmb.2012.0334. Epub 2012 Dec 6.
• [943] The Emerging Role of the SLCO1B3 Protein in Cancer Resistance.Protein Pept Lett. 2020;27(1):17-29. doi: 10.2174/0929866526666190926154248.
• [944] Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer.Biomed Pharmacother. 2015 Aug;74:233-42. doi: 10.1016/j.biopha.2015.08.026. Epub 2015 Aug 28.
• [945] Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-/Smads Pathway.Cells. 2019 Jun 25;8(6):635. doi: 10.3390/cells8060635.
• [946] Smad1 promotes colorectal cancer cell migration through Ajuba transactivation.Oncotarget. 2017 Nov 30;8(66):110415-110425. doi: 10.18632/oncotarget.22780. eCollection 2017 Dec 15.
• [947] M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer.Cancer Res. 2019 Jan 1;79(1):146-158. doi: 10.1158/0008-5472.CAN-18-0014. Epub 2018 Nov 6.
• [948] Mutational and expressional analysis of SMC2 gene in gastric and colorectal cancers with microsatellite instability.APMIS. 2014 Jun;122(6):499-504. doi: 10.1111/apm.12193. Epub 2014 Feb 1.
• [949] SMYD3 promoter hypomethylation is associated with the risk of colorectal cancer.Future Oncol. 2018 Aug;14(18):1825-1834. doi: 10.2217/fon-2017-0682. Epub 2018 Jul 4.
• [950] Integrating Immunotherapy Into Colorectal Cancer Care.Oncology (Williston Park). 2018 Oct 15;32(10):494-8.
• [951] Cellular prion protein and -synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch.PeerJ. 2018 Mar 6;6:e4506. doi: 10.7717/peerj.4506. eCollection 2018.
• [952] Radiation-induced SOD2 overexpression sensitizes colorectal cancer to radiation while protecting normal tissue.Oncotarget. 2017 Jan 31;8(5):7791-7800. doi: 10.18632/oncotarget.13954.
• [953] Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation.Int J Mol Sci. 2016 Nov 8;17(11):1860. doi: 10.3390/ijms17111860.
• [954] Long noncoding RNA lnc-sox5 modulates CRC tumorigenesis by unbalancing tumor microenvironment.Cell Cycle. 2017 Jul 3;16(13):1295-1301. doi: 10.1080/15384101.2017.1317416. Epub 2017 Jun 20.
• [955] MicroRNA-382 inhibits cell growth and migration in colorectal cancer by targeting SP1.Biol Res. 2018 Nov 24;51(1):51. doi: 10.1186/s40659-018-0200-9.
• [956] Differential expression of extracellular matrixrelated genes DCN, EPHA4, FN1, SPARC, SPON2 and SPP1 in colorectal carcinogenesis.Oncol Rep. 2019 Oct;42(4):1539-1548. doi: 10.3892/or.2019.7274. Epub 2019 Aug 9.
• [957] SPDEF Induces Quiescence of Colorectal Cancer Cells byChanging the Transcriptional Targets of -catenin.Gastroenterology. 2017 Jul;153(1):205-218.e8. doi: 10.1053/j.gastro.2017.03.048. Epub 2017 Apr 5.
• [958] Increased Sphingosine Kinase 1 Expression Predicts Distant Metastasis and Poor Outcome in Patients With Colorectal Cancer.Anticancer Res. 2019 Feb;39(2):663-670. doi: 10.21873/anticanres.13161.
• [959] Spinophilin loss correlates with poor patient prognosis in advanced stages of colon carcinoma.Clin Cancer Res. 2013 Jul 15;19(14):3925-35. doi: 10.1158/1078-0432.CCR-13-0057. Epub 2013 May 31.
• [960] SPOCK1 is up-regulated and promotes tumor growth via the PI3K/AKT signaling pathway in colorectal cancer.Biochem Biophys Res Commun. 2017 Jan 22;482(4):870-876. doi: 10.1016/j.bbrc.2016.11.126. Epub 2016 Nov 23.
• [961] Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial-mesenchymal transition.Oncogene. 2016 Jun 16;35(24):3151-62. doi: 10.1038/onc.2015.365. Epub 2015 Oct 5.
• [962] Anaplastic Lymphoma Kinase Rearrangement in Digestive Tract Cancer: Implication for Targeted Therapy in Chinese Population.PLoS One. 2015 Dec 17;10(12):e0144731. doi: 10.1371/journal.pone.0144731. eCollection 2015.
• [963] Squalene Epoxidase Correlates E-Cadherin Expression and Overall Survival in Colorectal Cancer Patients: The Impact on Prognosis and Correlation to Clinicopathologic Features.J Clin Med. 2019 May 8;8(5):632. doi: 10.3390/jcm8050632.
• [964] Targeting SREBP1 chemosensitizes colorectal cancer cells to gemcitabine by caspase-7 upregulation.Bioengineered. 2019 Dec;10(1):459-468. doi: 10.1080/21655979.2019.1676485.
• [965] SRGN Promotes Colorectal Cancer Metastasis as a Critical Downstream Target of HIF-1.Cell Physiol Biochem. 2018;48(6):2429-2440. doi: 10.1159/000492657. Epub 2018 Aug 17.
• [966] SRPK1 is a poor prognostic indicator and a novel potential therapeutic target for human colorectal cancer.Onco Targets Ther. 2018 Sep 3;11:5359-5370. doi: 10.2147/OTT.S172541. eCollection 2018.
• [967] Roles of Methylated DNA Biomarkers in Patients with Colorectal Cancer.Dis Markers. 2019 Mar 3;2019:2673543. doi: 10.1155/2019/2673543. eCollection 2019.
• [968] CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis.Tumour Biol. 2013 Apr;34(2):1215-24. doi: 10.1007/s13277-013-0664-8. Epub 2013 Jan 25.
• [969] Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis.Mucosal Immunol. 2019 Nov;12(6):1304-1315. doi: 10.1038/s41385-019-0204-y. Epub 2019 Sep 18.
• [970] STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.Cancer Res. 2013 Feb 15;73(4):1287-97. doi: 10.1158/0008-5472.CAN-12-1875. Epub 2012 Dec 14.
• [971] Upregulation of STC2 in colorectal cancer and its clinicopathological significance.Onco Targets Ther. 2019 Feb 15;12:1249-1258. doi: 10.2147/OTT.S191609. eCollection 2019.
• [972] Six-transmembrane epithelial antigen of the prostate 1 protects against increased oxidative stress via a nuclear erythroid 2-related factor pathway in colorectal cancer.Cancer Gene Ther. 2019 Sep;26(9-10):313-322. doi: 10.1038/s41417-018-0056-8. Epub 2018 Nov 7.
• [973] Identification of a developmental gene expression signature, including HOX genes, for the normal human colonic crypt stem cell niche: overexpression of the signature parallels stem cell overpopulation during colon tumorigenesis.Stem Cells Dev. 2014 Jan 15;23(2):167-79. doi: 10.1089/scd.2013.0039. Epub 2013 Nov 5.
• [974] Serine Threonine Kinase 17A Maintains the Epithelial State in Colorectal Cancer Cells.Mol Cancer Res. 2019 Apr;17(4):882-894. doi: 10.1158/1541-7786.MCR-18-0990. Epub 2019 Jan 17.
• [975] Enhanced SLP-2 promotes invasion and metastasis by regulating Wnt/-catenin signal pathway in colorectal cancer and predicts poor prognosis.Pathol Res Pract. 2019 Jan;215(1):57-67. doi: 10.1016/j.prp.2018.10.018. Epub 2018 Oct 24.
• [976] Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/-Catenin Signaling.Mol Cancer Res. 2019 Feb;17(2):521-531. doi: 10.1158/1541-7786.MCR-18-0054. Epub 2018 Sep 26.
• [977] Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy.Front Pharmacol. 2017 Mar 7;8:103. doi: 10.3389/fphar.2017.00103. eCollection 2017.
• [978] Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer.BMC Cancer. 2015 Apr 10;15:246. doi: 10.1186/s12885-015-1285-y.
• [979] TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.Nucleic Acids Res. 2019 Apr 23;47(7):3365-3382. doi: 10.1093/nar/gkz041.
• [980] Inflammatory genes are novel prognostic biomarkers for colorectal cancer.Int J Mol Med. 2018 Jul;42(1):368-380. doi: 10.3892/ijmm.2018.3631. Epub 2018 Apr 18.
• [981] Expression profile of the GA733 gene family in colorectal cancer: correlation with clinicopathological parameters.Genet Mol Res. 2015 Nov 23;14(4):14772-81. doi: 10.4238/2015.November.18.42.
• [982] TAP1 down-regulation elicits immune escape and poor prognosis in colorectal cancer.Oncoimmunology. 2017 Aug 7;6(11):e1356143. doi: 10.1080/2162402X.2017.1356143. eCollection 2017.
• [983] EBI-907, a novel BRAF(V600E) inhibitor, has potent oral anti-tumor activity and a broad kinase selectivity profile.Cancer Biol Ther. 2016;17(2):199-207. doi: 10.1080/15384047.2016.1139231. Epub 2016 Jan 25.
• [984] Prognostic significance of TBL1XR1 in predicting liver metastasis for early stage colorectal cancer.Surg Oncol. 2017 Mar;26(1):13-20. doi: 10.1016/j.suronc.2016.12.003. Epub 2016 Dec 8.
• [985] The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints.Cancer Discov. 2015 Jan;5(1):43-51. doi: 10.1158/2159-8290.CD-14-0863. Epub 2014 Oct 30.
• [986] A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.Cell Cycle. 2015;14(3):323-32. doi: 10.4161/15384101.2014.980643.
• [987] T-cell leukemia/lymphoma-1A predicts the clinical outcome for patients with stage II/III colorectal cancer.Biomed Pharmacother. 2017 Apr;88:924-930. doi: 10.1016/j.biopha.2017.01.128. Epub 2017 Feb 6.
• [988] TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study.J Oncol. 2019 May 23;2019:7091815. doi: 10.1155/2019/7091815. eCollection 2019.
• [989] Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369.
• [990] Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/-catenin signalling pathway via suppression of activator protein 2.Gut. 2016 Sep;65(9):1494-504. doi: 10.1136/gutjnl-2014-308392. Epub 2015 May 20.
• [991] TFF3 and TFF1 expression levels are elevated in colorectal cancer and promote the malignant behavior of colon cancer by activating the EMT process.Int J Oncol. 2019 Oct;55(4):789-804. doi: 10.3892/ijo.2019.4854. Epub 2019 Aug 5.
• [992] DcR3 induces epithelial-mesenchymal transition through activation of the TGF-3/SMAD signaling pathway in CRC.Oncotarget. 2016 Nov 22;7(47):77306-77318. doi: 10.18632/oncotarget.12639.
• [993] GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor-suppressor gene TGFR2 in colorectal cancer.Cancer Sci. 2020 Feb;111(2):343-355. doi: 10.1111/cas.14248. Epub 2019 Dec 27.
• [994] TGM2 interference regulates the angiogenesis and apoptosis of colorectal cancer via Wnt/-catenin pathway.Cell Cycle. 2019 May;18(10):1122-1134. doi: 10.1080/15384101.2019.1609831. Epub 2019 May 8.
• [995] TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer.Cell Death Dis. 2019 Mar 19;10(4):267. doi: 10.1038/s41419-019-1493-5.
• [996] Elevated expression of Tie1 is accompanied by acquisition of cancer stemness properties in colorectal cancer.Cancer Med. 2017 Jun;6(6):1378-1388. doi: 10.1002/cam4.1072. Epub 2017 May 2.
• [997] Functional TLR5 genetic variants affect human colorectal cancer survival.Cancer Res. 2013 Dec 15;73(24):7232-42. doi: 10.1158/0008-5472.CAN-13-1746. Epub 2013 Oct 23.
• [998] Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.Cancer Biomark. 2020;27(1):129-137. doi: 10.3233/CBM-190414.
• [999] Meat and fiber intake and interaction with pattern recognition receptors (TLR1, TLR2, TLR4, and TLR10) in relation to colorectal cancer in a Danish prospective, case-cohort study.Am J Clin Nutr. 2018 Mar 1;107(3):465-479. doi: 10.1093/ajcn/nqx011.
• [1000] Serum TLR2 and TLR4 levels in colorectal cancer and their association with systemic inflammatory markers, tumor characteristics, and disease outcome.APMIS. 2019 Aug;127(8):561-569. doi: 10.1111/apm.12971.
• [1001] TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression.Onco Targets Ther. 2018 Sep 18;11:5963-5971. doi: 10.2147/OTT.S174274. eCollection 2018.
• [1002] MALDI-imaging reveals thymosin beta-4 as an independent prognostic marker for colorectal cancer.Oncotarget. 2015 Dec 22;6(41):43869-80. doi: 10.18632/oncotarget.6103.
• [1003] Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy.Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2871-2880. doi: 10.1016/j.bbadis.2018.05.020. Epub 2018 May 25.
• [1004] DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1/NF1 switch axis on genomic locus.Int J Cancer. 2018 Jul 15;143(2):289-297. doi: 10.1002/ijc.31318. Epub 2018 Mar 1.
• [1005] BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5.Cancer Res. 2019 Mar 15;79(6):1191-1203. doi: 10.1158/0008-5472.CAN-18-3223. Epub 2019 Jan 23.
• [1006] Significance of Herpesvirus Entry Mediator Expression in Human Colorectal Liver Metastasis.Ann Surg Oncol. 2019 Nov;26(12):3982-3989. doi: 10.1245/s10434-019-07625-z. Epub 2019 Jul 16.
• [1007] OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer.Oncotarget. 2015 Nov 10;6(35):37588-99. doi: 10.18632/oncotarget.5940.
• [1008] Targeting CD137 enhances the efficacy of cetuximab.J Clin Invest. 2014 Jun;124(6):2668-82. doi: 10.1172/JCI73014. Epub 2014 May 16.
• [1009] Amelioration of colorectal cancer using negative lipidoid nanoparticles to encapsulate siRNA against APRIL by enema delivery mode.Pathol Oncol Res. 2014 Oct;20(4):953-64. doi: 10.1007/s12253-014-9779-5. Epub 2014 Apr 26.
• [1010] Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases.J Transl Med. 2013 Mar 20;11:70. doi: 10.1186/1479-5876-11-70.
• [1011] Tumor Necrosis Factor Ligand-Related Molecule 1A Regulates the Occurrence of Colitis-Associated Colorectal Cancer.Dig Dis Sci. 2018 Sep;63(9):2341-2350. doi: 10.1007/s10620-018-5126-0. Epub 2018 May 24.
• [1012] Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.Int J Oncol. 2015 Dec;47(6):2264-75. doi: 10.3892/ijo.2015.3192. Epub 2015 Oct 7.
• [1013] TNIK inhibition abrogates colorectal cancer stemness.Nat Commun. 2016 Aug 26;7:12586. doi: 10.1038/ncomms12586.
• [1014] TNK2 as a key drug target for the treatment of metastatic colorectal cancer.Int J Biol Macromol. 2018 Nov;119:48-52. doi: 10.1016/j.ijbiomac.2018.07.124. Epub 2018 Jul 20.
• [1015] Whole Transcriptome Analysis Identifies TNS4 as a Key Effector of Cetuximab and a Regulator of the Oncogenic Activity of KRAS Mutant Colorectal Cancer Cell Lines.Cells. 2019 Aug 12;8(8):878. doi: 10.3390/cells8080878.
• [1016] Herbal Medicines for Irinotecan-Induced Diarrhea.Front Pharmacol. 2019 Mar 29;10:182. doi: 10.3389/fphar.2019.00182. eCollection 2019.
• [1017] ZNF148 modulates TOP2A expression and cell proliferation via ceRNA regulatory mechanism in colorectal cancer.Medicine (Baltimore). 2017 Jan;96(1):e5845. doi: 10.1097/MD.0000000000005845.
• [1018] Inhibition of Girdin enhances chemosensitivity of colorectal cancer cells to oxaliplatin.World J Gastroenterol. 2014 Jul 7;20(25):8229-36. doi: 10.3748/wjg.v20.i25.8229.
• [1019] Maintenance BEZ235 Treatment Prolongs the Therapeutic Effect of the Combination of BEZ235 and Radiotherapy for Colorectal Cancer.Cancers (Basel). 2019 Aug 19;11(8):1204. doi: 10.3390/cancers11081204.
• [1020] Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.J Biol Chem. 2019 Dec 27;294(52):20246-20258. doi: 10.1074/jbc.RA119.009437. Epub 2019 Oct 16.
• [1021] The profile of melatonin receptors gene expression and genes associated with their activity in colorectal cancer: a preliminary report.J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):823-8.
• [1022] A Rare Variant P507L in TPP1 Interrupts TPP1-TIN2 Interaction, Influences Telomere Length, and Confers Colorectal Cancer Risk in Chinese Population.Cancer Epidemiol Biomarkers Prev. 2018 Sep;27(9):1029-1035. doi: 10.1158/1055-9965.EPI-18-0099. Epub 2018 Jun 11.
• [1023] Long noncoding RNA lncBRM promotes proliferation and invasion of colorectal cancer by sponging miR-204-3p and upregulating TPT1.Biochem Biophys Res Commun. 2019 Jan 22;508(4):1259-1263. doi: 10.1016/j.bbrc.2018.12.053. Epub 2018 Dec 15.
• [1024] The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.Ann Oncol. 2015 May;26(5):935-942. doi: 10.1093/annonc/mdv034. Epub 2015 Jan 28.
• [1025] TREM-1 promotes intestinal tumorigenesis.Sci Rep. 2017 Nov 1;7(1):14870. doi: 10.1038/s41598-017-14516-4.
• [1026] TREM2 Acts as a Tumor Suppressor in Colorectal Carcinoma through Wnt1/-catenin and Erk Signaling.Cancers (Basel). 2019 Sep 6;11(9):1315. doi: 10.3390/cancers11091315.
• [1027] Prognostic relevance of tripartite motif containing 24 expression in colorectal cancer.Pathol Res Pract. 2017 Oct;213(10):1271-1275. doi: 10.1016/j.prp.2017.08.008. Epub 2017 Aug 25.
• [1028] TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer.Int J Oncol. 2018 Aug;53(2):620-632. doi: 10.3892/ijo.2018.4408. Epub 2018 May 16.
• [1029] TRIM37 promotes epithelialmesenchymal transition in colorectal cancer.Mol Med Rep. 2017 Mar;15(3):1057-1062. doi: 10.3892/mmr.2017.6125. Epub 2017 Jan 16.
• [1030] Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.Oncol Rep. 2017 Oct;38(4):2480-2488. doi: 10.3892/or.2017.5896. Epub 2017 Aug 10.
• [1031] AKAP-9 promotes colorectal cancer development by regulating Cdc42 interacting protein 4.Biochim Biophys Acta. 2016 Jun;1862(6):1172-81. doi: 10.1016/j.bbadis.2016.03.012. Epub 2016 Apr 12.
• [1032] Glycolysis is essential for chemoresistance induced by transient receptor potential channel C5 in colorectal cancer.BMC Cancer. 2018 Feb 20;18(1):207. doi: 10.1186/s12885-018-4123-1.
• [1033] TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells.Mol Oncol. 2019 Nov;13(11):2393-2405. doi: 10.1002/1878-0261.12566. Epub 2019 Sep 12.
• [1034] TRPM7 deficiency suppresses cell proliferation, migration, and invasion in human colorectal cancer via regulation of epithelial-mesenchymal transition.Cancer Biomark. 2019;26(4):451-460. doi: 10.3233/CBM-190666.
• [1035] Mps1 is associated with the BRAF(V600E) mutation and predicts poor outcome in patients with colorectal cancer.Oncol Lett. 2019 Mar;17(3):2809-2817. doi: 10.3892/ol.2019.9924. Epub 2019 Jan 14.
• [1036] Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems.Cancer Lett. 2019 May 28;450:42-52. doi: 10.1016/j.canlet.2019.02.034. Epub 2019 Feb 18.
• [1037] Decreased expression of thioredoxin interacting protein mRNA in inflamed colonic mucosa in patients with ulcerative colitis.Oncol Rep. 2007 Sep;18(3):531-5.
• [1038] FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway.Cancer Lett. 2020 Feb 1;470:29-42. doi: 10.1016/j.canlet.2019.11.042. Epub 2019 Dec 4.
• [1039] Determination of thymidine phosphorylase expression level facilitates recurrence risk stratification in stage II/III colorectal cancer following adjuvant chemotherapy with oral fluoropyrimidines.Oncol Lett. 2019 Jun;17(6):5267-5274. doi: 10.3892/ol.2019.10181. Epub 2019 Mar 21.
• [1040] MicroRNA-7 inhibits colorectal cancer cell proliferation, migration and invasion via TYRO3 and phosphoinositide 3-kinase/protein B kinase/mammalian target of rapamycin pathway suppression.Int J Mol Med. 2018 Nov;42(5):2503-2514. doi: 10.3892/ijmm.2018.3864. Epub 2018 Sep 7.
• [1041] The Pivotal Role of TRP Channels in Homeostasis and Diseases throughout the Gastrointestinal Tract.Int J Mol Sci. 2019 Oct 24;20(21):5277. doi: 10.3390/ijms20215277.
• [1042] UCHL5 expression associates with improved survival in lymph-node-positive rectal cancer.Tumour Biol. 2017 Jul;39(7):1010428317716078. doi: 10.1177/1010428317716078.
• [1043] UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses.Cell Rep. 2019 Aug 27;28(9):2306-2316.e5. doi: 10.1016/j.celrep.2019.07.097.
• [1044] Dose adjustment of irinotecan based on UGT1A1 polymorphisms in patients with colorectal cancer.Cancer Chemother Pharmacol. 2019 Jan;83(1):123-129. doi: 10.1007/s00280-018-3711-8. Epub 2018 Oct 30.
• [1045] Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.Pharmacogenomics J. 2013 Apr;13(2):148-58. doi: 10.1038/tpj.2011.65. Epub 2012 Jan 17.
• [1046] MicroRNA?35b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers.Oncol Rep. 2015 Mar;33(3):1342-8. doi: 10.3892/or.2014.3694. Epub 2014 Dec 23.
• [1047] Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.J Biol Chem. 2016 Nov 18;291(47):24628-24640. doi: 10.1074/jbc.M116.738567. Epub 2016 Sep 28.
• [1048] Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia.Epigenetics. 2014 Aug;9(8):1092-100. doi: 10.4161/epi.29222. Epub 2014 May 16.
• [1049] Ubiquitin specific peptidase 5 regulates colorectal cancer cell growth by stabilizing Tu translation elongation factor.Theranostics. 2019 May 31;9(14):4208-4220. doi: 10.7150/thno.33803. eCollection 2019.
• [1050] USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth. Biochem Pharmacol. 2017 May 1;131:29-39.
• [1051] HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer.Cell Death Dis. 2018 Sep 26;9(10):1004. doi: 10.1038/s41419-018-1019-6.
• [1052] Association of the HLA-G 3'UTR polymorphisms with colorectal cancer in Italy: a first insight.Int J Immunogenet. 2016 Feb;43(1):32-9. doi: 10.1111/iji.12243. Epub 2015 Dec 21.
• [1053] ErbB4/KITENIN-Mediated Signaling is Activated in Cetuximab-Resistant Colorectal Cancer Cells.J Nanosci Nanotechnol. 2019 Feb 1;19(2):1166-1171. doi: 10.1166/jnn.2019.15899.
• [1054] The effect of ALA-PDT under normoxia and cobalt chloride (CoCl(2))-induced hypoxia on adhesion molecules (ICAM-1, VCAM-1) secretion by colorectal cancer cells.Photodiagnosis Photodyn Ther. 2017 Sep;19:103-115. doi: 10.1016/j.pdpdt.2017.05.005. Epub 2017 May 8.
• [1055] MiR-490-3p Functions As a Tumor Suppressor by Inhibiting Oncogene VDAC1 Expression in Colorectal Cancer.J Cancer. 2018 Mar 14;9(7):1218-1230. doi: 10.7150/jca.23662. eCollection 2018.
• [1056] Association Between Hypoxia-Inducible Factor-2 (HIF-2) Expression and Colorectal Cancer and Its Prognostic Role: a Systematic Analysis.Cell Physiol Biochem. 2018;48(2):516-527. doi: 10.1159/000491806. Epub 2018 Jul 18.
• [1057] MTA1 Is Up-regulated in Colorectal Cancer and Is Inversely Correlated with Lymphatic Metastasis.Cancer Genomics Proteomics. 2015 Nov-Dec;12(6):339-45.
• [1058] Vasoactive intestinal peptide increases apoptosis of hepatocellular carcinoma by inhibiting the cAMP/Bcl-xL pathway.Cancer Sci. 2019 Jan;110(1):235-244. doi: 10.1111/cas.13861. Epub 2018 Dec 4.
• [1059] Screening of a specific peptide binding to VPAC1 receptor from a phage display peptide library.PLoS One. 2013;8(1):e54264. doi: 10.1371/journal.pone.0054264. Epub 2013 Jan 24.
• [1060] B7-H4 facilitates proliferation and metastasis of colorectal carcinoma cell through PI3K/Akt/mTOR signaling pathway.Clin Exp Med. 2020 Feb;20(1):79-86. doi: 10.1007/s10238-019-00590-7. Epub 2019 Oct 29.
• [1061] PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.Cell Death Dis. 2017 Mar 16;8(3):e2686. doi: 10.1038/cddis.2017.111.
• [1062] WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy.Clin Cancer Res. 2016 Sep 15;22(18):4612-22. doi: 10.1158/1078-0432.CCR-15-2703. Epub 2016 Apr 27.
• [1063] High expression of WWP1 predicts poor prognosis and associates with tumor progression in human colorectal cancer.Am J Cancer Res. 2018 Feb 1;8(2):256-265. eCollection 2018.
• [1064] Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.Sci Adv. 2019 Sep 4;5(9):eaaw9162. doi: 10.1126/sciadv.aaw9162. eCollection 2019 Sep.
• [1065] Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.Mol Genet Genomic Med. 2018 Apr 17;6(4):533-40. doi: 10.1002/mgg3.402. Online ahead of print.
• [1066] The role of double-strand break repair, translesion synthesis, and interstrand crosslinks in colorectal cancer progression-clinicopathological data and survival.J Surg Oncol. 2020 Apr;121(5):906-916. doi: 10.1002/jso.25737. Epub 2019 Oct 25.
• [1067] An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.Oncogenesis. 2019 Feb 19;8(3):13. doi: 10.1038/s41389-019-0125-3.
• [1068] The role of ABC transporters in progression and clinical outcome of colorectal cancer.Mutagenesis. 2012 Mar;27(2):187-96. doi: 10.1093/mutage/ger075.
• [1069] Insulin promotes progression of colon cancer by upregulation of ACAT1.Lipids Health Dis. 2018 May 24;17(1):122. doi: 10.1186/s12944-018-0773-x.
• [1070] Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.Eur J Clin Nutr. 2012 Dec;66(12):1303-8. doi: 10.1038/ejcn.2012.173. Epub 2012 Nov 14.
• [1071] CC chemokine ligand 7 expression in liver metastasis of colorectal cancer.Oncol Rep. 2012 Aug;28(2):689-94. doi: 10.3892/or.2012.1815. Epub 2012 May 14.
• [1072] A truncated form of IKK is responsible for specific nuclear IKK activity in colorectal cancer.Cell Rep. 2012 Oct 25;2(4):840-54. doi: 10.1016/j.celrep.2012.08.028. Epub 2012 Oct 4.
• [1073] Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas.Biochimie. 2012 Feb;94(2):487-93. doi: 10.1016/j.biochi.2011.08.017. Epub 2011 Aug 31.
• [1074] MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL.Carcinogenesis. 2012 Apr;33(4):732-9. doi: 10.1093/carcin/bgs020. Epub 2012 Jan 27.
• [1075] Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.BMC Med Genet. 2012 Oct 5;13:94. doi: 10.1186/1471-2350-13-94.
• [1076] Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases.Br J Cancer. 2011 Mar 15;104(6):1007-12. doi: 10.1038/bjc.2011.33. Epub 2011 Feb 22.
• [1077] In vivo tumor imaging using a novel RNAi-based detection mechanism.Nanomedicine. 2012 May;8(4):393-8. doi: 10.1016/j.nano.2012.02.004. Epub 2012 Feb 17.
• [1078] Expression of FK506 binding protein 65 (FKBP65) is decreased in epithelial ovarian cancer cells compared to benign tumor cells and to ovarian epithelium.Tumour Biol. 2011 Aug;32(4):671-6. doi: 10.1007/s13277-011-0167-4. Epub 2011 Mar 12.
• [1079] Identification of GABRA1 and LAMA2 as new DNA methylation markers in colorectal cancer.Int J Oncol. 2012 Mar;40(3):889-98. doi: 10.3892/ijo.2011.1245. Epub 2011 Oct 25.
• [1080] Identification of novel DNA methylation markers in colorectal cancer using MIRA-based microarrays.Oncol Rep. 2012 Jul;28(1):99-104. doi: 10.3892/or.2012.1779. Epub 2012 Apr 23.
• [1081] Abnormal expression of GADD45B in human colorectal carcinoma.J Transl Med. 2012 Oct 30;10:215. doi: 10.1186/1479-5876-10-215.
• [1082] Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer.Clin Cancer Res. 2012 Oct 1;18(19):5412-26. doi: 10.1158/1078-0432.CCR-12-1780. Epub 2012 Aug 2.
• [1083] Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment.Clin Cancer Res. 2015 Aug 15;21(16):3695-704. doi: 10.1158/1078-0432.CCR-14-2457. Epub 2015 May 5.
• [1084] Lymph node tissue kallikrein-related peptidase 6 mRNA: a progression marker for colorectal cancer.Br J Cancer. 2012 Jun 26;107(1):150-7. doi: 10.1038/bjc.2012.220. Epub 2012 Jun 14.
• [1085] Role of anthocyanin-enriched purple-fleshed sweet potato p40 in colorectal cancer prevention.Mol Nutr Food Res. 2013 Nov;57(11):1908-17. doi: 10.1002/mnfr.201300040. Epub 2013 Jun 19.
• [1086] Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages.Int J Oncol. 2012 Jul;41(1):260-6. doi: 10.3892/ijo.2012.1441. Epub 2012 Apr 19.
• [1087] Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas.PLoS One. 2012;7(1):e30020. doi: 10.1371/journal.pone.0030020. Epub 2012 Jan 19.
• [1088] Association of genetic variants in tachykinins pathway genes with colorectal cancer risk.Int J Colorectal Dis. 2012 Nov;27(11):1429-36. doi: 10.1007/s00384-012-1478-7. Epub 2012 Jun 26.
• [1089] The haplotypes of TNFRSF17 polymorphisms are associated with colon cancer in a Korean population.Int J Colorectal Dis. 2012 Jun;27(6):701-7. doi: 10.1007/s00384-011-1364-8. Epub 2011 Nov 24.
• [1090] Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.PLoS One. 2012;7(5):e37312. doi: 10.1371/journal.pone.0037312. Epub 2012 May 17.
• [1091] CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer.Oncol Rep. 2011 May;25(5):1297-306. doi: 10.3892/or.2011.1193. Epub 2011 Feb 22.
• [1092] Propofol promotes apoptosis of colorectal cancer cells via alleviating the suppression of lncRNA HOXA11-AS on miRNA let-7i.Biochem Cell Biol. 2020 Apr;98(2):90-98. doi: 10.1139/bcb-2018-0235. Epub 2019 Apr 23.
• [1093] The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer.Int J Cancer. 2019 May 1;144(9):2320-2329. doi: 10.1002/ijc.32045. Epub 2019 Jan 11.
• [1094] Selection and characterization of novel DNA aptamer against colorectal carcinoma Caco-2 cells.Biotechnol Appl Biochem. 2019 May;66(3):412-418. doi: 10.1002/bab.1737. Epub 2019 Feb 21.
• [1095] Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?.Pharmacogenomics J. 2019 Oct;19(5):465-472. doi: 10.1038/s41397-019-0078-0. Epub 2019 Feb 4.
• [1096] PAR2 Inhibition Enhanced the Sensitivity of Colorectal Cancer Cells to 5-FU and Reduced EMT Signaling.Oncol Res. 2019 Jul 12;27(7):779-788. doi: 10.3727/096504018X15442985680348. Epub 2019 Mar 6.
• [1097] The Flavonoid Metabolite 2,4,6-Trihydroxybenzoic Acid Is a CDK Inhibitor and an Anti-Proliferative Agent: A Potential Role in Cancer Prevention.Cancers (Basel). 2019 Mar 26;11(3):427. doi: 10.3390/cancers11030427.
• [1098] miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells.Int J Cancer. 2011 Mar 15;128(6):1269-79. doi: 10.1002/ijc.25452.
• [1099] Associations between single-nucleotide polymorphisms and inflammatory bowel disease-associated colorectal cancers in inflammatory bowel disease patients: a meta-analysis.Clin Transl Oncol. 2017 Aug;19(8):1018-1027. doi: 10.1007/s12094-017-1634-1. Epub 2017 Feb 27.
• [1100] Integrative expression quantitative trait locus-based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression.Eur J Cancer. 2018 Apr;93:1-9. doi: 10.1016/j.ejca.2018.01.065. Epub 2018 Feb 9.
• [1101] LC-MS-based metabolomics revealed SLC25A22 as an essential regulator of aspartate-derived amino acids and polyamines in KRAS-mutant colorectal cancer. Oncotarget. 2017 Sep 20;8(60):101333-101344.
• [1102] ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma.Curr Med Chem. 2019;26(7):1224-1250. doi: 10.2174/0929867325666180105103637.
• [1103] Downregulation of Annexin A11 (ANXA11) Inhibits Cell Proliferation, Invasion, and Migration via the AKT/GSK-3 Pathway in Gastric Cancer.Med Sci Monit. 2018 Jan 7;24:149-160. doi: 10.12659/msm.905372.
• [1104] High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.Hum Pathol. 2019 Feb;84:62-70. doi: 10.1016/j.humpath.2018.09.002. Epub 2018 Sep 18.
• [1105] Deletions at SLC18A1 increased the risk of CRC and lower SLC18A1 expression associated with poor CRC outcome.Carcinogenesis. 2017 Oct 26;38(11):1057-1062. doi: 10.1093/carcin/bgx088.
• [1106] Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.Sci Rep. 2016 Dec 7;6:38415. doi: 10.1038/srep38415.
• [1107] Ornithine decarboxylase gene is overexpressed in colorectal carcinoma.World J Gastroenterol. 2005 Apr 21;11(15):2244-8. doi: 10.3748/wjg.v11.i15.2244.
• [1108] A missense variant in PTPN12 associated with the risk of colorectal cancer by modifying Ras/MEK/ERK signaling.Cancer Epidemiol. 2019 Apr;59:109-114. doi: 10.1016/j.canep.2019.01.013. Epub 2019 Feb 4.
• [1109] Quantitative analysis of gene expression in fixed colorectal carcinoma samples as a method for biomarker validation.Mol Med Rep. 2016 Jun;13(6):5084-92. doi: 10.3892/mmr.2016.5200. Epub 2016 Apr 27.
• [1110] Upregulation of SLC2A3 gene and prognosis in colorectal carcinoma: analysis of TCGA data.BMC Cancer. 2019 Apr 3;19(1):302. doi: 10.1186/s12885-019-5475-x.
• [1111] Transcriptome analysis reveals an altered expression profile of zinc transporters in colorectal cancer.J Cell Biochem. 2018 Dec;119(12):9707-9719. doi: 10.1002/jcb.27285. Epub 2018 Aug 20.
• [1112] Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.Drug Metab Rev. 2015 May;47(2):199-221. doi: 10.3109/03602532.2014.996649. Epub 2015 Feb 17.
• [1113] PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer.Oncogene. 2016 Jun 9;35(23):3004-15. doi: 10.1038/onc.2015.363. Epub 2015 Oct 5.
• [1114] Upregulated solute carrier family 37 member 1 in colorectal cancer is associated with poor patient outcome and metastasis.Oncol Lett. 2018 Feb;15(2):2065-2072. doi: 10.3892/ol.2017.7559. Epub 2017 Dec 8.
• [1115] The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer.Int J Cancer. 2012 Sep 15;131(6):1479-85. doi: 10.1002/ijc.27399. Epub 2012 Jan 11.
• [1116] Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.Acta Biochim Biophys Sin (Shanghai). 2017 Oct 1;49(10):926-934. doi: 10.1093/abbs/gmx094.
• [1117] Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.PLoS One. 2013;8(3):e58733. doi: 10.1371/journal.pone.0058733. Epub 2013 Mar 14.
• [1118] Ectopic expression of band 3 anion transport protein in colorectal cancer revealed in an autoimmune hemolytic anemia patient.Hum Pathol. 2019 Jan;83:193-198. doi: 10.1016/j.humpath.2018.07.020. Epub 2018 Jul 29.
• [1119] Four targeted genes for predicting the prognosis of colorectal cancer: A bioinformatics analysis case.Oncol Lett. 2019 Nov;18(5):5043-5054. doi: 10.3892/ol.2019.10866. Epub 2019 Sep 13.
• [1120] Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.Sci Rep. 2014 Apr 30;4:4852. doi: 10.1038/srep04852.
• [1121] Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps.J Nutr Biochem. 2017 Sep;47:35-40. doi: 10.1016/j.jnutbio.2017.04.016. Epub 2017 May 5.
• [1122] Up-regulation of SLC9A9 Promotes Cancer Progression and Is Involved in Poor Prognosis in Colorectal Cancer.Anticancer Res. 2017 May;37(5):2255-2263. doi: 10.21873/anticanres.11562.
• [1123] Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells.Oncogene. 2003 Jul 24;22(30):4765-73. doi: 10.1038/sj.onc.1206684.
• [1124] Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans.Cancer Sci. 2006 Aug;97(8):774-9. doi: 10.1111/j.1349-7006.2006.00241.x. Epub 2006 Jun 23.
• [1125] Activity of thymidylate synthetase, thymidine kinase and galactokinase in primary and xenografted human colorectal cancers in relation to their chromosomal patterns.Int J Cancer. 1991 Mar 12;47(5):670-4. doi: 10.1002/ijc.2910470507.
• [1126] HIT family genes: FHIT but not PKCI-1/HINT produces altered transcripts in colorectal cancer.Br J Cancer. 1999 Nov;81(5):874-80. doi: 10.1038/sj.bjc.6690779.
• [1127] MANBA polymorphism was related to increased risk of colorectal cancer in Swedish but not in Chinese populations.Acta Oncol. 2008;47(3):372-8. doi: 10.1080/02841860701644052. Epub 2007 Sep 26.
• [1128] Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis.Mol Cell. 2020 Jan 2;77(1):138-149.e5. doi: 10.1016/j.molcel.2019.10.015. Epub 2019 Nov 14.
• [1129] Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population.Int J Colorectal Dis. 2007 Oct;22(10):1185-94. doi: 10.1007/s00384-007-0308-9. Epub 2007 May 5.
• [1130] Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression.Acta Oncol. 2007;46(8):1107-12. doi: 10.1080/02841860701403061.
• [1131] miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer.Cancer Manag Res. 2018 Nov 29;10:6537-6547. doi: 10.2147/CMAR.S185789. eCollection 2018.
• [1132] Sucrase-isomaltase is an independent prognostic marker for colorectal carcinoma.Dis Colon Rectum. 1995 Dec;38(12):1257-64. doi: 10.1007/BF02049149.
• [1133] A novel approach to detect differentially expressed genes from count-based digital databases by normalizing with housekeeping genes.Genomics. 2009 Sep;94(3):211-6. doi: 10.1016/j.ygeno.2009.05.003. Epub 2009 May 13.
• [1134] Amplification of the hst-1 gene in human esophageal carcinomas.Jpn J Cancer Res. 1988 May;79(5):584-8. doi: 10.1111/j.1349-7006.1988.tb00026.x.
• [1135] UDP-glucuronosyltransferase 1A1*6 and *28 polymorphisms as indicators of initial dose level of irinotecan to reduce risk of neutropenia in patients receiving FOLFIRI for colorectal cancer.Int J Clin Oncol. 2016 Aug;21(4):696-703. doi: 10.1007/s10147-015-0937-x. Epub 2015 Dec 28.
• [1136] Associations between UGT2B7 polymorphisms and cancer susceptibility: A meta-analysis.Gene. 2019 Jul 20;706:115-123. doi: 10.1016/j.gene.2019.05.025. Epub 2019 May 10.
• [1137] Association between N142D genetic polymorphism of GSTO2 and susceptibility to colorectal cancer.Mol Biol Rep. 2011 Oct;38(7):4309-13. doi: 10.1007/s11033-010-0555-7. Epub 2010 Nov 27.
• [1138] Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.Clin Cancer Res. 2005 Apr 1;11(7):2612-9. doi: 10.1158/1078-0432.CCR-04-1258.
• [1139] Overexpressed ACP5 has prognostic value in colorectal cancer and promotes cell proliferation and tumorigenesis via FAK/PI3K/AKT signaling pathway.Am J Cancer Res. 2019 Jan 1;9(1):22-35. eCollection 2019.
• [1140] Associations of calcium and dairy product intakes with all-cause, all-cancer, colorectal cancer and CHD mortality among older women in the Iowa Women's Health Study.Br J Nutr. 2019 May;121(10):1188-1200. doi: 10.1017/S000711451900045X. Epub 2019 Mar 5.
• [1141] The long noncoding RNA CTA-941F9.9 is frequently downregulated and may serve as a biomarker for carcinogenesis in colorectal cancer.J Clin Lab Anal. 2019 Nov;33(9):e22986. doi: 10.1002/jcla.22986. Epub 2019 Jul 25.
• [1142] Associations of Pre- and Postdiagnosis Diet Quality With Risk of Mortality Among Men and Women With Colorectal Cancer.J Clin Oncol. 2018 Oct 19;36(34):JCO1800714. doi: 10.1200/JCO.18.00714. Online ahead of print.
• [1143] Hypermethylation Of ADHFE1 Promotes The Proliferation Of Colorectal Cancer Cell Via Modulating Cell Cycle Progression.Onco Targets Ther. 2019 Oct 4;12:8105-8115. doi: 10.2147/OTT.S223423. eCollection 2019.
• [1144] Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.PLoS One. 2013 Nov 25;8(11):e80158. doi: 10.1371/journal.pone.0080158. eCollection 2013.
• [1145] Treatment of cancer cells with chemotherapeutic drugs results in profound changes in expression of genes encoding aldehyde-metabolizing enzymes.J Cancer. 2019 Jul 10;10(18):4256-4263. doi: 10.7150/jca.32608. eCollection 2019.
• [1146] Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.Br J Cancer. 2017 Nov 7;117(10):1537-1543. doi: 10.1038/bjc.2017.304. Epub 2017 Sep 7.
• [1147] MSI-L/EMAST is a predictive biomarker for metastasis in colorectal cancer patients.J Cell Physiol. 2019 Aug;234(8):13128-13136. doi: 10.1002/jcp.27983. Epub 2018 Dec 13.
• [1148] The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer.Dis Markers. 2018 Jan 31;2018:5280736. doi: 10.1155/2018/5280736. eCollection 2018.
• [1149] CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response.Cell Death Dis. 2017 Aug 24;8(8):e3009. doi: 10.1038/cddis.2017.405.
• [1150] Nucleoside diphosphate kinase 2 confers acquired 5-fluorouracil resistance in colorectal cancer cells.Artif Cells Nanomed Biotechnol. 2018;46(sup1):896-905. doi: 10.1080/21691401.2018.1439835. Epub 2018 Feb 23.
• [1151] Carboxypeptidase A4 promotes cell growth via activating STAT3 and ERK signaling pathways and predicts a poor prognosis in colorectal cancer.Int J Biol Macromol. 2019 Oct 1;138:125-134. doi: 10.1016/j.ijbiomac.2019.07.028. Epub 2019 Jul 4.
• [1152] CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of -catenin signaling.Exp Cell Res. 2015 Feb 15;331(2):377-86. doi: 10.1016/j.yexcr.2014.12.008. Epub 2014 Dec 31.
• [1153] Meta-analysis of cytochrome P-450 2C9 polymorphism and colorectal cancer risk.PLoS One. 2012;7(11):e49134. doi: 10.1371/journal.pone.0049134. Epub 2012 Nov 7.
• [1154] Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis.Cancer Prev Res (Phila). 2012 Feb;5(2):197-204. doi: 10.1158/1940-6207.CAPR-11-0320. Epub 2011 Nov 4.
• [1155] Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.BMC Cancer. 2013 Nov 6;13:526. doi: 10.1186/1471-2407-13-526.
• [1156] Power of screening tests for colorectal cancer enhanced by high levels of M2-PK in addition to FOBT.Intern Emerg Med. 2017 Apr;12(3):333-339. doi: 10.1007/s11739-017-1610-3. Epub 2017 Feb 2.
• [1157] Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.Nat Genet. 2014 Jun;46(6):533-42. doi: 10.1038/ng.2985. Epub 2014 May 18.
• [1158] Overexpression of flavin-containing monooxygenase 5 predicts poor prognosis in patients with colorectal cancer.Oncol Lett. 2018 Mar;15(3):3923-3927. doi: 10.3892/ol.2018.7724. Epub 2018 Jan 4.
• [1159] Elevated Venous Thromboembolism Risk Following Colectomy for IBD Is Equal to Those for Colorectal Cancer for Ninety Days After Surgery.Dis Colon Rectum. 2018 Mar;61(3):375-381. doi: 10.1097/DCR.0000000000001036.
• [1160] Role of -glutamyl cyclotransferase as a therapeutic target for colorectal cancer based on the lentivirus-mediated system.Anticancer Drugs. 2016 Nov;27(10):1011-20. doi: 10.1097/CAD.0000000000000407.
• [1161] Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization.Cell Death Dis. 2019 Jan 17;10(2):40. doi: 10.1038/s41419-018-1291-5.
• [1162] Fucosylation Deficiency in Mice Leads to Colitis andAdenocarcinoma.Gastroenterology. 2017 Jan;152(1):193-205.e10. doi: 10.1053/j.gastro.2016.09.004. Epub 2016 Sep 14.
• [1163] Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer.Oncogene. 2016 Nov 3;35(44):5795-5806. doi: 10.1038/onc.2016.113. Epub 2016 Apr 11.
• [1164] Investigation of FIH-1 and SOCS3 expression in KRAS mutant and wild-type patients with colorectal cancer.Tumour Biol. 2016 Jul;37(7):8841-8. doi: 10.1007/s13277-015-4723-1. Epub 2016 Jan 9.
• [1165] Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells.BMC Genet. 2016 Dec 22;17(Suppl 3):156. doi: 10.1186/s12863-016-0459-1.
• [1166] Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair.Cell Rep. 2018 Oct 9;25(2):398-412.e6. doi: 10.1016/j.celrep.2018.09.022.
• [1167] S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis.Oncotarget. 2017 Aug 12;8(45):78851-78869. doi: 10.18632/oncotarget.20234. eCollection 2017 Oct 3.
• [1168] Low folate status, and MTHFR 677C?T and MTR 2756A?G polymorphisms associated with colorectal cancer risk in Thais: a case-control study.Nutr Res. 2019 Dec;72:80-91. doi: 10.1016/j.nutres.2019.10.008. Epub 2019 Oct 25.
• [1169] miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression.Cancer Manag Res. 2019 Jun 6;11:5317-5332. doi: 10.2147/CMAR.S197733. eCollection 2019.
• [1170] DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1 expression through the PI3K-AKT pathway.Cancer Manag Res. 2018 Oct 16;10:4615-4629. doi: 10.2147/CMAR.S172008. eCollection 2018.
• [1171] Period 1 and estrogen receptor-beta are downregulated in Chinese colon cancers.Int J Clin Exp Pathol. 2015 Jul 1;8(7):8178-88. eCollection 2015.
• [1172] Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer.Front Pharmacol. 2017 Feb 13;8:47. doi: 10.3389/fphar.2017.00047. eCollection 2017.
• [1173] Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.Oncogene. 2008 Dec 4;27(53):6729-37. doi: 10.1038/onc.2008.322. Epub 2008 Sep 15.
• [1174] The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBP rather than Enterotoxigenic Bacteroides fragilis Infection.Oxid Med Cell Longev. 2016;2016:2353560. doi: 10.1155/2016/2353560. Epub 2016 Jun 28.
• [1175] Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.Mol Oncol. 2015 Jun;9(6):1207-17. doi: 10.1016/j.molonc.2015.02.009. Epub 2015 Mar 4.
• [1176] Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.PLoS One. 2017 Jan 19;12(1):e0170233. doi: 10.1371/journal.pone.0170233. eCollection 2017.
• [1177] UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan. Clin Cancer Res. 2005 Feb 1;11(3):1226-36.
• [1178] Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.Genes Chromosomes Cancer. 2014 Jul;53(7):568-78. doi: 10.1002/gcc.22167. Epub 2014 Mar 28.
• [1179] The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk.Cancer. 2013 Jul 1;119(13):2477-85. doi: 10.1002/cncr.28009. Epub 2013 Apr 10.
• [1180] Vitamin D Regulation of the Uridine Phosphorylase 1 Gene and Uridine-Induced DNA Damage in Colon in African Americans and European Americans.Gastroenterology. 2018 Oct;155(4):1192-1204.e9. doi: 10.1053/j.gastro.2018.06.049. Epub 2018 Jun 30.
• [1181] Chemo-radio-gene therapy for colorectal cancer cells using Escherichia coli uracil phosphoribosyltransferase gene.Anticancer Res. 2003 Mar-Apr;23(2B):1343-8.
• [1182] Methylation of the KEAP1 gene promoter region in human colorectal cancer.BMC Cancer. 2012 Feb 13;12:66. doi: 10.1186/1471-2407-12-66.
• [1183] Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer.Mol Med Rep. 2011 Mar-Apr;4(2):363-8. doi: 10.3892/mmr.2011.431. Epub 2011 Jan 25.
• [1184] Association study of genetic variants in estrogen metabolic pathway genes and colorectal cancer risk and survival.Arch Toxicol. 2018 Jun;92(6):1991-1999. doi: 10.1007/s00204-018-2195-y. Epub 2018 May 16.
• [1185] Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma.Cancer Sci. 2007 Jul;98(7):992-9. doi: 10.1111/j.1349-7006.2007.00488.x. Epub 2007 Apr 23.
• [1186] Promoter hypermethylation of the ADAM23 gene in colorectal cancer cell lines and cancer tissues.Int J Cancer. 2009 Mar 15;124(6):1258-62. doi: 10.1002/ijc.24023.
• [1187] MiR-198 affects the proliferation and apoptosis of colorectal cancer through regulation of ADAM28/JAK-STAT signaling pathway.Eur Rev Med Pharmacol Sci. 2019 Feb;23(4):1487-1493. doi: 10.26355/eurrev_201902_17106.
• [1188] Knockdown of the novel proteasome subunit Adrm1 located on the 20q13 amplicon inhibits colorectal cancer cell migration, survival and tumorigenicity.Oncol Rep. 2009 Feb;21(2):531-7.
• [1189] Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.Exp Mol Pathol. 2008 Dec;85(3):201-6. doi: 10.1016/j.yexmp.2008.09.006. Epub 2008 Oct 11.
• [1190] Detection of circulating microRNAs with Ago2 complexes to monitor the tumor dynamics of colorectal cancer patients during chemotherapy.Int J Cancer. 2019 May 1;144(9):2169-2180. doi: 10.1002/ijc.31960. Epub 2019 Jan 7.
• [1191] Mutation analysis of aryl hydrocarbon receptor interacting protein (AIP) gene in colorectal, breast, and prostate cancers.Br J Cancer. 2007 Jan 29;96(2):352-6. doi: 10.1038/sj.bjc.6603573.
• [1192] Long non-coding RNA MALAT1 increases AKAP-9 expression by promoting SRPK1-catalyzed SRSF1 phosphorylation in colorectal cancer cells.Oncotarget. 2016 Mar 8;7(10):11733-43. doi: 10.18632/oncotarget.7367.
• [1193] Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis.Cancer Prev Res (Phila). 2010 Jul;3(7):829-38. doi: 10.1158/1940-6207.CAPR-09-0110. Epub 2010 Jun 22.
• [1194] Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.Endocr Relat Cancer. 2011 Jul 4;18(4):465-78. doi: 10.1530/ERC-11-0083. Print 2011 Aug.
• [1195] Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.Cytotechnology. 2019 Feb;71(1):35-44. doi: 10.1007/s10616-018-0259-8. Epub 2019 Jan 4.
• [1196] MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues.Int J Oncol. 2010 Apr;36(4):765-75. doi: 10.3892/ijo_00000552.
• [1197] Annexin A3 depletion overcomes resistance to oxaliplatin in colorectal cancer via the MAPK signaling pathway.J Cell Biochem. 2019 Sep;120(9):14585-14593. doi: 10.1002/jcb.28720. Epub 2019 Apr 18.
• [1198] Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice.Cancer Res. 2007 Sep 15;67(18):8565-73. doi: 10.1158/0008-5472.CAN-07-1593.
• [1199] Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB.Int J Cancer. 2008 Mar 15;122(6):1426-9. doi: 10.1002/ijc.23239.
• [1200] Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.Cell Death Dis. 2018 Jun 4;9(6):673. doi: 10.1038/s41419-018-0707-6.
• [1201] ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers.Gene. 2004 Jul 7;336(1):59-71. doi: 10.1016/j.gene.2004.01.025.
• [1202] DC-SIGN-LEF1/TCF1-miR-185 feedback loop promotes colorectal cancer invasion and metastasis.Cell Death Differ. 2020 Jan;27(1):379-395. doi: 10.1038/s41418-019-0361-2. Epub 2019 Jun 19.
• [1203] Targeting ARID1A-mutant colorectal cancer: depletion of ARID1B increases radiosensitivity and modulates DNA damage response.Sci Rep. 2019 Dec 3;9(1):18207. doi: 10.1038/s41598-019-54757-z.
• [1204] Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.Gut. 2004 Apr;53(4):573-80. doi: 10.1136/gut.2003.030841.
• [1205] TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles.Mol Oncol. 2008 Oct;2(3):233-40. doi: 10.1016/j.molonc.2008.06.003. Epub 2008 Jun 18.
• [1206] Cytoplasmic Asporin promotes cell migration by regulating TGF-/Smad2/3 pathway and indicates a poor prognosis in colorectal cancer.Cell Death Dis. 2019 Feb 6;10(2):109. doi: 10.1038/s41419-019-1376-9.
• [1207] Meta-analysis of association studies of CYP1A1 genetic polymorphisms with digestive tract cancer susceptibility in Chinese.Asian Pac J Cancer Prev. 2014;15(11):4689-95. doi: 10.7314/apjcp.2014.15.11.4689.
• [1208] SCF/c-KIT Signaling Increased Mucin2 Production by Maintaining Atoh1 Expression in Mucinous Colorectal Adenocarcinoma.Int J Mol Sci. 2018 May 22;19(5):1541. doi: 10.3390/ijms19051541.
• [1209] ATP11A is a novel predictive marker for metachronous metastasis of colorectal cancer.Oncol Rep. 2010 Feb;23(2):505-10.
• [1210] (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations.Br J Cancer. 2019 Jan;120(2):229-237. doi: 10.1038/s41416-018-0350-0. Epub 2018 Dec 17.
• [1211] POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?.Anticancer Res. 2008 Mar-Apr;28(2B):1221-7.
• [1212] ATP6L promotes metastasis of colorectal cancer by inducing epithelial-mesenchymal transition.Cancer Sci. 2020 Feb;111(2):477-488. doi: 10.1111/cas.14283. Epub 2020 Jan 6.
• [1213] Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer.PLoS One. 2019 Feb 15;14(2):e0211564. doi: 10.1371/journal.pone.0211564. eCollection 2019.
• [1214] Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors.Genes Chromosomes Cancer. 2012 Dec;51(12):1133-43. doi: 10.1002/gcc.21998. Epub 2012 Aug 25.
• [1215] Silencing Bag-1 gene via magnetic gold nanoparticle-delivered siRNA plasmid for colorectal cancer therapy in vivo and in vitro.Tumour Biol. 2016 Aug;37(8):10365-74. doi: 10.1007/s13277-016-4926-0. Epub 2016 Feb 4.
• [1216] MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer.Cell Death Dis. 2019 Feb 15;10(3):152. doi: 10.1038/s41419-019-1403-x.
• [1217] Genipin Enhances the Therapeutic Effects of Oxaliplatin by Upregulating BIM in Colorectal Cancer.Mol Cancer Ther. 2019 Apr;18(4):751-761. doi: 10.1158/1535-7163.MCT-18-0196. Epub 2019 Feb 20.
• [1218] Cucurbitacin B inhibits cell proliferation and induces cell apoptosis in colorectal cancer by modulating methylation status of BTG3.Neoplasma. 2019 Jul 23;66(4):593-602. doi: 10.4149/neo_2018_180929N729. Epub 2019 Apr 24.
• [1219] Blood vessel epicardial substance reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis.Carcinogenesis. 2019 Sep 18;40(9):1086-1098. doi: 10.1093/carcin/bgz007.
• [1220] BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway.J Cell Physiol. 2020 May;235(5):4834-4842. doi: 10.1002/jcp.29361. Epub 2019 Oct 23.
• [1221] Expression analysis of circulating plasma long noncoding RNAs in colorectal cancer: The relevance of lncRNAs ATB and CCAT1 as potential clinical hallmarks.J Cell Physiol. 2019 Dec;234(12):22028-22033. doi: 10.1002/jcp.28765. Epub 2019 May 15.
• [1222] Interaction between C2ORF68 and HuR in human colorectal cancer.Oncol Rep. 2019 Mar;41(3):1918-1928. doi: 10.3892/or.2019.6973. Epub 2019 Jan 21.
• [1223] CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation.Oncogene. 2019 Jun;38(23):4574-4589. doi: 10.1038/s41388-019-0740-7. Epub 2019 Feb 11.
• [1224] Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization.Gastroenterology. 2006 Dec;131(6):1913-24. doi: 10.1053/j.gastro.2006.10.021. Epub 2006 Oct 15.
• [1225] Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer.BMC Gastroenterol. 2009 Oct 20;9:79. doi: 10.1186/1471-230X-9-79.
• [1226] Overexpression of m-calpain in human colorectal adenocarcinomas.Cancer Epidemiol Biomarkers Prev. 2004 Oct;13(10):1604-9.
• [1227] Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers.Neoplasia. 2005 Aug;7(8):771-8. doi: 10.1593/neo.05235.
• [1228] Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer.Br J Cancer. 2009 Feb 10;100(3):511-23. doi: 10.1038/sj.bjc.6604884. Epub 2009 Jan 20.
• [1229] Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?.BMC Cancer. 2004 Jul 9;4:31. doi: 10.1186/1471-2407-4-31.
• [1230] Overexpression of CCDC34 in colorectal cancer and its involvement in tumor growth, apoptosis and invasion.Mol Med Rep. 2018 Jan;17(1):465-473. doi: 10.3892/mmr.2017.7860. Epub 2017 Oct 24.
• [1231] Discovery and scoring of protein interaction subnetworks discriminative of late stage human colon cancer.Mol Cell Proteomics. 2009 Apr;8(4):827-45. doi: 10.1074/mcp.M800428-MCP200. Epub 2008 Dec 19.
• [1232] Inhibition of cytosolic chaperonin CCT-1 expression depletes proliferation of colorectal carcinoma in vitro.J Surg Oncol. 2010 Oct 1;102(5):419-23. doi: 10.1002/jso.21625.
• [1233] The ratio of splicing variants of MGC-24/CD164, a sialomucin, correlates with the metastatic potential of colorectal carcinomas.J Biochem. 2000 Jun;127(6):1103-7. doi: 10.1093/oxfordjournals.jbchem.a022704.
• [1234] Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.Br J Cancer. 2019 Jan;120(1):69-78. doi: 10.1038/s41416-018-0198-3. Epub 2018 Oct 31.
• [1235] Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer.J Immunother Cancer. 2017 Mar 21;5:22. doi: 10.1186/s40425-017-0222-9. eCollection 2017.
• [1236] The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.Oncotarget. 2017 Apr 4;8(14):23603-23612. doi: 10.18632/oncotarget.15377.
• [1237] Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.Clin Cancer Res. 2008 Oct 15;14(20):6487-95. doi: 10.1158/1078-0432.CCR-08-1086.
• [1238] Silencing of cadherin-17 enhances apoptosis and inhibits autophagy in colorectal cancer cells.Biomed Pharmacother. 2018 Dec;108:331-337. doi: 10.1016/j.biopha.2018.09.020. Epub 2018 Sep 15.
• [1239] 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.BMC Cancer. 2007 May 2;7:72. doi: 10.1186/1471-2407-7-72.
• [1240] Cis-acting elements required for expression of the nonspecific cross-reacting antigen gene in colorectal carcinoma.Gastroenterology. 1997 Mar;112(3):776-82. doi: 10.1053/gast.1997.v112.pm9041239.
• [1241] Pleotropic role of RNA binding protein CELF2 in autophagy induction.Mol Carcinog. 2019 Aug;58(8):1400-1409. doi: 10.1002/mc.23023. Epub 2019 Apr 24.
• [1242] Elevated expression of C10orf3 (chromosome 10 open reading frame 3) is involved in the growth of human colon tumor.Oncogene. 2006 Jan 19;25(3):480-6. doi: 10.1038/sj.onc.1209051.
• [1243] Expression of CIAPIN1 in human colorectal cancer and its correlation with prognosis.BMC Cancer. 2010 Sep 3;10:477. doi: 10.1186/1471-2407-10-477.
• [1244] Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer.Cancer Res. 2006 Jan 15;66(2):763-9. doi: 10.1158/0008-5472.CAN-05-3771.
• [1245] CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer.Genes Immun. 2011 Dec;12(8):653-62. doi: 10.1038/gene.2011.43. Epub 2011 Jun 30.
• [1246] Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12.Int J Colorectal Dis. 2007 Jun;22(6):651-9. doi: 10.1007/s00384-006-0197-3. Epub 2006 Oct 18.
• [1247] Disruption of sialic acid metabolism drives tumor growth by augmenting CD8(+) T cell apoptosis.Int J Cancer. 2019 May 1;144(9):2290-2302. doi: 10.1002/ijc.32084. Epub 2019 Jan 3.
• [1248] Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer.Int J Cancer. 2003 Sep 10;106(4):505-509. doi: 10.1002/ijc.11264.
• [1249] Colorectal carcinogenesis is associated with stromal expression of COL11A1 and COL5A2.Carcinogenesis. 2001 Jun;22(6):875-8. doi: 10.1093/carcin/22.6.875.
• [1250] Cysteine-rich intestinal protein 1 suppresses apoptosis and chemosensitivity to 5-fluorouracil in colorectal cancer through ubiquitin-mediated Fas degradation.J Exp Clin Cancer Res. 2019 Mar 8;38(1):120. doi: 10.1186/s13046-019-1117-z.
• [1251] In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein.DNA Cell Biol. 2011 Sep;30(9):715-26. doi: 10.1089/dna.2011.1240. Epub 2011 May 25.
• [1252] Screening of tumor suppressor genes on 1q31.1-32.1 in Chinese patients with sporadic colorectal cancer.Chin Med J (Engl). 2008 Dec 20;121(24):2479-86.
• [1253] Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.Oncol Rep. 2008 Jul;20(1):3-11.
• [1254] Expression profile of cancer-testis genes in 121 human colorectal cancer tissue and adjacent normal tissue.Clin Cancer Res. 2005 Mar 1;11(5):1809-14. doi: 10.1158/1078-0432.CCR-04-1365.
• [1255] MicroRNA-155 acts as a tumor suppressor in colorectal cancer by targeting CTHRC1 in vitro.Oncol Lett. 2018 Apr;15(4):5561-5568. doi: 10.3892/ol.2018.8069. Epub 2018 Feb 16.
• [1256] Mutation and expression of the beta-catenin-interacting protein ICAT in human colorectal tumors.Jpn J Clin Oncol. 2002 Sep;32(9):358-62. doi: 10.1093/jjco/hyf068.
• [1257] Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers.APMIS. 2009 Dec;117(12):880-5. doi: 10.1111/j.1600-0463.2009.02550.x.
• [1258] A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apoptosis by Regulating KLF2 and CUL4A Expression in Colorectal Cancer.Mol Ther Nucleic Acids. 2018 Sep 7;12:684-697. doi: 10.1016/j.omtn.2018.06.012. Epub 2018 Jul 6.
• [1259] Oncogenic KRAS Drives Immune Suppression in Colorectal Cancer.Cancer Cell. 2019 Apr 15;35(4):535-537. doi: 10.1016/j.ccell.2019.03.008.
• [1260] ELR+ CXC chemokine expression in benign and malignant colorectal conditions.BMC Cancer. 2008 Jun 25;8:178. doi: 10.1186/1471-2407-8-178.
• [1261] Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.J Mol Med (Berl). 2019 Jan;97(1):89-102. doi: 10.1007/s00109-018-1716-8. Epub 2018 Nov 20.
• [1262] DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells.Onco Targets Ther. 2018 Dec 28;12:233-241. doi: 10.2147/OTT.S190814. eCollection 2019.
• [1263] Oncogenic splicing abnormalities induced by DEAD-Box Helicase 56 amplification in colorectal cancer.Cancer Sci. 2019 Oct;110(10):3132-3144. doi: 10.1111/cas.14163. Epub 2019 Aug 29.
• [1264] Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells.Mol Carcinog. 2018 May;57(5):579-589. doi: 10.1002/mc.22781. Epub 2018 Jan 30.
• [1265] Expression of NOX Family Genes and Their Clinical Significance in Colorectal Cancer.Dig Dis Sci. 2018 Sep;63(9):2332-2340. doi: 10.1007/s10620-018-5121-5. Epub 2018 May 21.
• [1266] Impact of genetic counseling and testing on colorectal cancer screening behavior.Genet Test. 2002 Winter;6(4):303-6. doi: 10.1089/10906570260471831.
• [1267] Overexpression of miR-301a-3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer-1 and runt-related transcription factor 3.J Cell Biochem. 2019 Apr;120(4):6078-6089. doi: 10.1002/jcb.27894. Epub 2018 Oct 25.
• [1268] Molecular characterization of the DYX1C1 gene and its application as a cancer biomarker.J Cancer Res Clin Oncol. 2009 Feb;135(2):265-70. doi: 10.1007/s00432-008-0445-8. Epub 2008 Jul 10.
• [1269] Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer.Exp Cell Res. 2019 May 15;378(2):124-130. doi: 10.1016/j.yexcr.2019.03.015. Epub 2019 Mar 8.
• [1270] Differential expression of DUSP2 in left- and right-sided colon cancer is associated with poor prognosis in colorectal cancer.Oncol Lett. 2018 Apr;15(4):4207-4214. doi: 10.3892/ol.2018.7881. Epub 2018 Jan 26.
• [1271] Genetic Polymorphisms in APC, DVL2, and AXIN1 Are Associated with Susceptibility, Advanced TNM Stage or Tumor Location in Colorectal Cancer.Tohoku J Exp Med. 2019 Nov;249(3):173-183. doi: 10.1620/tjem.249.173.
• [1272] Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4.Int J Oncol. 2013 Dec;43(6):2015-22. doi: 10.3892/ijo.2013.2131. Epub 2013 Oct 8.
• [1273] Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood: ECT2 in Diagnosis of Colorectal Cancer.Int J Mol Sci. 2017 Mar 31;18(4):743. doi: 10.3390/ijms18040743.
• [1274] Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle.Int J Oncol. 2009 May;34(5):1181-9.
• [1275] rs12904 polymorphism in the 3'-untranslated region of ephrin A1 ligand and the risk of sporadic colorectal cancer in the Iranian population.J Cancer Res Ther. 2019 Jan-Mar;15(1):15-19. doi: 10.4103/jcrt.JCRT_766_17.
• [1276] Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.Cell. 2002 Oct 18;111(2):251-63. doi: 10.1016/s0092-8674(02)01015-2.
• [1277] EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.Leukemia. 2017 Jul;31(7):1547-1554. doi: 10.1038/leu.2016.359. Epub 2016 Nov 28.
• [1278] Eukaryotic translation initiation factor 3 subunit G promotes human colorectal cancer.Am J Transl Res. 2019 Feb 15;11(2):612-623. eCollection 2019.
• [1279] LncRNA FAL1 promotes carcinogenesis by regulation of miR-637/NUPR1 pathway in colorectal cancer.Int J Biochem Cell Biol. 2019 Jan;106:46-56. doi: 10.1016/j.biocel.2018.09.015. Epub 2018 Sep 26.
• [1280] Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas.Cancer Res. 2001 Nov 1;61(21):7722-6.
• [1281] The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways.Oncogene. 2009 Mar 26;28(12):1506-17. doi: 10.1038/onc.2008.499. Epub 2009 Jan 26.
• [1282] The RNA-binding protein ESRP1 promotes human colorectal cancer progression.Oncotarget. 2017 Feb 7;8(6):10007-10024. doi: 10.18632/oncotarget.14318.
• [1283] Adenovirus-mediated overexpression FADD induces a significant antitumor effect on human colorectal cancer cells both in vitro and in vivo.Cell Mol Biol (Noisy-le-grand). 2018 May 15;64(6):31-35.
• [1284] FANCD2 mRNA overexpression is a bona fide indicator of lymph node metastasis in human colorectal cancer.Ann Surg Oncol. 2010 Sep;17(9):2341-8. doi: 10.1245/s10434-010-1002-7. Epub 2010 Mar 26.
• [1285] FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis.J Exp Clin Cancer Res. 2019 Mar 4;38(1):112. doi: 10.1186/s13046-019-1043-0.
• [1286] FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression.Cell Death Dis. 2019 Apr 25;10(5):351. doi: 10.1038/s41419-019-1588-z.
• [1287] Association analyses identify 31 new risk loci for colorectal cancer susceptibility.Nat Commun. 2019 May 14;10(1):2154. doi: 10.1038/s41467-019-09775-w.
• [1288] MiR-10b suppresses the growth and metastasis of colorectal cancer cell by targeting FGF13.Eur Rev Med Pharmacol Sci. 2019 Jan;23(2):576-587. doi: 10.26355/eurrev_201901_16870.
• [1289] High incidence of coamplification of hst-1 and int-2 genes in human esophageal carcinomas.Cancer Res. 1989 Oct 15;49(20):5505-8.
• [1290] Filamin A interacting protein 1-like expression inhibits progression in colorectal cancer.Oncotarget. 2016 Nov 1;7(44):72229-72241. doi: 10.18632/oncotarget.12664.
• [1291] Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.Oncol Rep. 2010 Jun;23(6):1609-17. doi: 10.3892/or_00000802.
• [1292] The antibody-drug conjugate target landscape across a broad range of tumour types.Ann Oncol. 2017 Dec 1;28(12):3083-3091. doi: 10.1093/annonc/mdx541.
• [1293] Identification of methylation-silenced genes in colorectal cancer cell lines: genomic screening using oligonucleotide arrays.Scand J Gastroenterol. 2007 Dec;42(12):1486-94. doi: 10.1080/00365520701491173.
• [1294] Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas.World J Gastroenterol. 2015 Mar 7;21(9):2629-37. doi: 10.3748/wjg.v21.i9.2629.
• [1295] Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression.Cancer Res. 1997 Dec 1;57(23):5201-6.
• [1296] Growth Factor-Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer.Mol Cancer Res. 2019 Mar;17(3):697-708. doi: 10.1158/1541-7786.MCR-18-0666. Epub 2019 Jan 3.
• [1297] GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.Sci Rep. 2018 Jan 22;8(1):1368. doi: 10.1038/s41598-018-19542-4.
• [1298] The potential clinical value of GML and the p53 gene as a predictor of chemosensitivity for colorectal cancer.Int J Clin Oncol. 2001 Apr;6(2):90-6. doi: 10.1007/pl00012089.
• [1299] Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.Pathol Oncol Res. 2020 Apr;26(2):967-976. doi: 10.1007/s12253-019-00651-y. Epub 2019 Mar 29.
• [1300] GPX2 suppression of H(2)O(2) stress regulates cervical cancer metastasis and apoptosis via activation of the -catenin-WNT pathway.Onco Targets Ther. 2019 Aug 19;12:6639-6651. doi: 10.2147/OTT.S208781. eCollection 2019.
• [1301] Expression of 32-kDa laminin-binding protein mRNA in colon cancer tissues.J Surg Res. 1996 Feb 15;61(1):120-6. doi: 10.1006/jsre.1996.0091.
• [1302] GSTT2 promoter polymorphisms and colorectal cancer risk.BMC Cancer. 2007 Jan 25;7:16. doi: 10.1186/1471-2407-7-16.
• [1303] Guanylate Cyclase C: A Current Hot Target, from Physiology to Pathology.Curr Med Chem. 2018;25(16):1879-1908. doi: 10.2174/0929867325666171205150310.
• [1304] Sixty years of follow-up of Hiroshima and Nagasaki survivors: current progress in molecular epidemiology studies.Mutat Res. 2008 Jul-Aug;659(1-2):109-17. doi: 10.1016/j.mrrev.2008.02.001. Epub 2008 Feb 12.
• [1305] Loss of HACE1 promotes colorectal cancer cell migration via upregulation of YAP1.J Cell Physiol. 2019 Jun;234(6):9663-9672. doi: 10.1002/jcp.27653. Epub 2018 Oct 26.
• [1306] Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.Oncogene. 2002 Sep 12;21(41):6387-94. doi: 10.1038/sj.onc.1205751.
• [1307] Utility of DNA Flow Cytometric Analysis of Paraffin-embedded Tissue in the Risk Stratification and Management of 'Indefinite for dysplasia' in Patients With Inflammatory Bowel Disease.J Crohns Colitis. 2019 Mar 30;13(4):472-481. doi: 10.1093/ecco-jcc/jjy193.
• [1308] A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer.Sci Rep. 2016 Jun 17;6:28083. doi: 10.1038/srep28083.
• [1309] Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors.Tumour Biol. 2011 Oct;32(5):845-52. doi: 10.1007/s13277-011-0156-7. Epub 2011 Jan 28.
• [1310] Gene expression signatures for HOXA4, HOXA9, and HOXD10 reveal alterations in transcriptional regulatory networks in colon cancer.J Cell Physiol. 2019 Aug;234(8):13042-13056. doi: 10.1002/jcp.27975. Epub 2018 Dec 14.
• [1311] circIFT80 Functions as a ceRNA of miR-1236-3p to Promote Colorectal Cancer Progression.Mol Ther Nucleic Acids. 2019 Dec 6;18:375-387. doi: 10.1016/j.omtn.2019.08.024. Epub 2019 Sep 3.
• [1312] Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced integrin 3 transcriptional activating and MAPK/AKT signalling.Mol Cancer. 2019 Mar 1;18(1):31. doi: 10.1186/s12943-019-0955-9.
• [1313] MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells.Int J Oncol. 2007 Apr;30(4):985-92. doi: 10.3892/ijo.30.4.985.
• [1314] Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.Clin Cancer Res. 2003 Dec 15;9(17):6410-8.
• [1315] Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer.Anticancer Res. 2010 Dec;30(12):4811-8.
• [1316] Significant overexpression of Hsp110 gene during colorectal cancer progression.Oncol Rep. 2009 May;21(5):1235-41. doi: 10.3892/or_00000346.
• [1317] Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.Clin Cancer Res. 2004 Nov 15;10(22):7475-83. doi: 10.1158/1078-0432.CCR-04-0689.
• [1318] Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer.Oncotarget. 2016 Dec 27;7(52):86039-86050. doi: 10.18632/oncotarget.13325.
• [1319] IMP1 3' UTR shortening enhances metastatic burden in colorectal cancer.Carcinogenesis. 2019 Jun 10;40(4):569-579. doi: 10.1093/carcin/bgy153.
• [1320] LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer.Mol Cancer. 2019 Dec 2;18(1):174. doi: 10.1186/s12943-019-1105-0.
• [1321] IL-17R deletion predicts high-grade colorectal cancer and poor clinical outcomes.Int J Cancer. 2019 Jul 15;145(2):548-558. doi: 10.1002/ijc.32122. Epub 2019 Jan 28.
• [1322] ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.Cell Res. 2020 Feb;30(2):163-178. doi: 10.1038/s41422-019-0257-1. Epub 2019 Nov 26.
• [1323] Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells.Chromosoma. 2001 May;110(2):65-74. doi: 10.1007/s004120100130.
• [1324] INPP4B exerts a dual function in the stemness of colorectal cancer stem-like cells through regulating Sox2 and Nanog expression.Carcinogenesis. 2020 Mar 13;41(1):78-90. doi: 10.1093/carcin/bgz110.
• [1325] Elevated levels of RanBP7 mRNA in colorectal carcinoma are associated with increased proliferation and are similar to the transcription pattern of the proto-oncogene c-myc.Biochem Biophys Res Commun. 2000 May 10;271(2):537-43. doi: 10.1006/bbrc.2000.2666.
• [1326] High expression of IQGAP3 indicates poor prognosis in colorectal cancer patients.Int J Biol Markers. 2019 Dec;34(4):348-355. doi: 10.1177/1724600819876951. Epub 2019 Sep 23.
• [1327] Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITG4-PDCD4) as predictor of ... Epigenetics. 2014 Jan;9(1):129-41.
• [1328] Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, isa promising recurrence prediction biomarker in colorectal cancer.Mol Cancer. 2019 Feb 4;18(1):19. doi: 10.1186/s12943-019-0945-y.
• [1329] KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice.BMC Cancer. 2010 Dec 1;10:660. doi: 10.1186/1471-2407-10-660.
• [1330] TIP60 represses activation of endogenous retroviral elements.Nucleic Acids Res. 2018 Oct 12;46(18):9456-9470. doi: 10.1093/nar/gky659.
• [1331] KDM4B promotes DNA damage response via STAT3 signaling and is a target of CREB in colorectal cancer cells.Mol Cell Biochem. 2018 Dec;449(1-2):81-90. doi: 10.1007/s11010-018-3345-5. Epub 2018 Apr 9.
• [1332] Inhibition of KHSRP sensitizes colorectal cancer to 5-fluoruracil through miR-501-5p-mediated ERRFI1 mRNA degradation.J Cell Physiol. 2020 Feb;235(2):1576-1587. doi: 10.1002/jcp.29076. Epub 2019 Jul 16.
• [1333] MiR-382 functions as tumor suppressor and chemosensitizer in colorectal cancer.Biosci Rep. 2019 Aug 9;39(8):BSR20180441. doi: 10.1042/BSR20180441. Print 2019 Aug 30.
• [1334] Clinical significance and biological role of KLF17 as a tumour suppressor in colorectal cancer.Oncol Rep. 2019 Nov;42(5):2117-2129. doi: 10.3892/or.2019.7324. Epub 2019 Sep 18.
• [1335] Immunohistochemical expression of p16, p53, and p63 in colorectal adenomas and adenocarcinomas.Dis Colon Rectum. 2006 May;49(5):588-94. doi: 10.1007/s10350-006-0515-4.
• [1336] Next Generation Proteomics for Clinical Biomarker Detection Using SWATH-MS.Methods Mol Biol. 2019;1977:3-15. doi: 10.1007/978-1-4939-9232-4_1.
• [1337] The KLF14 Transcription Factor Regulates Glycolysis by Downregulating LDHB in Colorectal Cancer.Int J Biol Sci. 2019 Jan 1;15(3):628-635. doi: 10.7150/ijbs.30652. eCollection 2019.
• [1338] Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.Oncogene. 2005 Apr 28;24(19):3100-9. doi: 10.1038/sj.onc.1208520.
• [1339] Differential expression of the LOX family genes in human colorectal adenocarcinomas.Oncol Rep. 2009 Oct;22(4):799-804. doi: 10.3892/or_00000502.
• [1340] High Expression of LTBP2 Contributes to Poor Prognosis in Colorectal Cancer Patients and Correlates with the Mesenchymal Colorectal Cancer Subtype.Dis Markers. 2019 Mar 10;2019:5231269. doi: 10.1155/2019/5231269. eCollection 2019.
• [1341] microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis.J Transl Med. 2014 May 1;12:109. doi: 10.1186/1479-5876-12-109.
• [1342] Evaluation of the association between the -1304T>G polymorphism in the promoter of the MKK4 gene and the risk of colorectal cancer: a PRISMA-compliant meta-analysis.Ann Transl Med. 2019 Apr;7(7):144. doi: 10.21037/atm.2019.03.08.
• [1343] Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer.Eur J Cancer. 1999 Jun;35(6):935-8. doi: 10.1016/s0959-8049(99)00035-0.
• [1344] Muscleblindlike 1 destabilizes Snail mRNA and suppresses the metastasis of colorectal cancer cells via the Snail/Ecadherin axis.Int J Oncol. 2019 Mar;54(3):955-965. doi: 10.3892/ijo.2019.4691. Epub 2019 Jan 18.
• [1345] Hypermethylated and downregulated MEIS2 are involved in stemness properties and oxaliplatin-based chemotherapy resistance of colorectal cancer.J Cell Physiol. 2019 Aug;234(10):18180-18191. doi: 10.1002/jcp.28451. Epub 2019 Mar 11.
• [1346] Significant antitumor effect of an antibody against TMEM180, a new colorectal cancer-specific molecule.Cancer Sci. 2019 Feb;110(2):761-770. doi: 10.1111/cas.13907. Epub 2019 Jan 4.
• [1347] Association of MICA-TM and MICB C1_2_A microsatellite polymorphisms with tumor progression in patients with colorectal cancer.J Clin Immunol. 2009 Jul;29(4):545-54. doi: 10.1007/s10875-009-9288-6. Epub 2009 Apr 8.
• [1348] The ubiquitination ligase SMURF2 reduces aerobic glycolysis and colorectal cancer cell proliferation by promoting ChREBP ubiquitination and degradation.J Biol Chem. 2019 Oct 4;294(40):14745-14756. doi: 10.1074/jbc.RA119.007508. Epub 2019 Aug 13.
• [1349] Mob-1, a Ras target gene, is overexpressed in colorectal cancer.Oncogene. 1997 Apr 3;14(13):1607-10. doi: 10.1038/sj.onc.1200957.
• [1350] Prognostic Relevance and Function of MSX2 in Colorectal Cancer.J Diabetes Res. 2017;2017:3827037. doi: 10.1155/2017/3827037. Epub 2017 Feb 12.
• [1351] Metastasis-associated protein 3 in colorectal cancer determines tumor recurrence and prognosis.Oncotarget. 2017 Jun 6;8(23):37164-37171. doi: 10.18632/oncotarget.16332.
• [1352] Mutational analysis of mononucleotide repeats in dual specificity tyrosine phosphatase genes in gastric and colon carcinomas with microsatellite instability.APMIS. 2010 May;118(5):389-93. doi: 10.1111/j.1600-0463.2010.02612.x.
• [1353] The biogenesis and biological functions of circular RNAs and their molecular diagnostic values in cancers.J Clin Lab Anal. 2020 Jan;34(1):e23049. doi: 10.1002/jcla.23049. Epub 2019 Sep 25.
• [1354] Effects of supplemental calcium and vitamin D on tight-junction proteins and mucin-12 expression in the normal rectal mucosa of colorectal adenoma patients.Mol Carcinog. 2019 Jul;58(7):1279-1290. doi: 10.1002/mc.23010. Epub 2019 Apr 2.
• [1355] MUC13 promotes the development of colitis-associated colorectal tumors via -catenin activity.Oncogene. 2019 Nov;38(48):7294-7310. doi: 10.1038/s41388-019-0951-y. Epub 2019 Aug 19.
• [1356] Combined Diagnostic Efficacy of Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Mean Platelet Volume (MPV) as Biomarkers of Systemic Inflammation in the Diagnosis of Colorectal Cancer.Dis Markers. 2019 Jan 17;2019:6036979. doi: 10.1155/2019/6036979. eCollection 2019.
• [1357] Induction of chromosomal instability in colonic cells by the human polyomavirus JC virus.Cancer Res. 2003 Nov 1;63(21):7256-62.
• [1358] Mad2 and p27 expression profiles in colorectal cancer and its clinical significance.World J Gastroenterol. 2004 Nov 1;10(21):3218-20. doi: 10.3748/wjg.v10.i21.3218.
• [1359] MYEOV (myeloma overexpressed gene) drives colon cancer cell migration and is regulated by PGE2.J Exp Clin Cancer Res. 2010 Jun 22;29(1):81. doi: 10.1186/1756-9966-29-81.
• [1360] Somatic Mutations and Intratumoral Heterogeneity of MYH11 Gene in Gastric and Colorectal Cancers.Appl Immunohistochem Mol Morphol. 2018 Sep;26(8):562-566. doi: 10.1097/PAI.0000000000000484.
• [1361] Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer.Genes Chromosomes Cancer. 2005 Jun;43(2):162-71. doi: 10.1002/gcc.20180.
• [1362] Hypermethylation of the MYOD1 gene is a novel prognostic factor in patients with colorectal cancer.Int J Mol Med. 2004 Mar;13(3):413-7.
• [1363] Generation of novel monoclonal antibodies and their application for detecting ARD1 expression in colorectal cancer.Cancer Lett. 2008 Jun 8;264(1):83-92. doi: 10.1016/j.canlet.2008.01.028. Epub 2008 Mar 5.
• [1364] The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia.Ann Surg Oncol. 2006 Feb;13(2):253-62. doi: 10.1245/ASO.2006.12.011. Epub 2006 Jan 20.
• [1365] High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.Am J Gastroenterol. 2009 Jul;104(7):1790-801. doi: 10.1038/ajg.2009.230. Epub 2009 Jun 2.
• [1366] Nectin-1 Expression in Colorectal Cancer: Is There a Group of Patients with High Risk for Early Disease Recurrence?.Oncology. 2019;96(6):318-325. doi: 10.1159/000499569. Epub 2019 Mar 27.
• [1367] Neurogenic differentiation factor 1 promotes colorectal cancer cell proliferation and tumorigenesis by suppressing the p53/p21 axis.Cancer Sci. 2020 Jan;111(1):175-185. doi: 10.1111/cas.14233. Epub 2019 Dec 10.
• [1368] Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.Int J Cancer. 2013 May 1;132(9):2209-16. doi: 10.1002/ijc.27888. Epub 2012 Oct 29.
• [1369] Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer.Onco Targets Ther. 2019 Mar 20;12:2095-2104. doi: 10.2147/OTT.S192923. eCollection 2019.
• [1370] Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling.PLoS One. 2009 Nov 24;4(11):e7982. doi: 10.1371/journal.pone.0007982.
• [1371] Genes regulated by Nkx2-3 in sporadic and inflammatory bowel disease-associated colorectal cancer cell lines.Dig Dis Sci. 2010 Nov;55(11):3171-80. doi: 10.1007/s10620-010-1138-0. Epub 2010 Feb 18.
• [1372] rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.Sci Rep. 2016 Nov 15;6:36874. doi: 10.1038/srep36874.
• [1373] Overexpression of nm23-H4 RNA in colorectal and renal tumours.Anticancer Res. 2001 Jul-Aug;21(4A):2821-5.
• [1374] DNA content and cell kinetics in colorectal carcinoma: flow cytometric analysis of primary tumor and liver metastases.Tumori. 1995 May-Jun;81(3 Suppl):12-5.
• [1375] Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.PLoS One. 2014 Jun 3;9(6):e96767. doi: 10.1371/journal.pone.0096767. eCollection 2014.
• [1376] Nitrogen Permease Regulator-Like-2 Exhibited Anti-Tumor Effects And Enhanced The Sensitivity Of Colorectal Cancer Cells To Oxaliplatin And 5-Fluorouracil.Onco Targets Ther. 2019 Oct 18;12:8637-8644. doi: 10.2147/OTT.S219562. eCollection 2019.
• [1377] The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells.Cancer Lett. 2011 Oct 28;309(2):137-44. doi: 10.1016/j.canlet.2011.05.025. Epub 2011 Jun 22.
• [1378] A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level.J Nutr Biochem. 2010 Feb;21(2):98-106. doi: 10.1016/j.jnutbio.2008.11.002. Epub 2009 Jan 20.
• [1379] Next-generation sequencing analysis of multiplex families with atypical psychosis.Transl Psychiatry. 2018 Oct 15;8(1):221. doi: 10.1038/s41398-018-0272-x.
• [1380] Expression of angiostatic factors in colorectal cancer.Int J Oncol. 1999 Dec;15(6):1221-5. doi: 10.3892/ijo.15.6.1221.
• [1381] The lncRNA FEZF1-AS1 Promotes the Progression of Colorectal Cancer Through Regulating OTX1 and Targeting miR-30a-5p.Oncol Res. 2020 Feb 7;28(1):51-63. doi: 10.3727/096504019X15619783964700. Epub 2019 Jul 3.
• [1382] Biological evaluations of newly-designed Pt(II) and Pd(II) complexes using spectroscopic and molecular docking approaches.J Biomol Struct Dyn. 2019 Aug;37(13):3422-3433. doi: 10.1080/07391102.2018.1516164. Epub 2018 Nov 1.
• [1383] Cancer/testis antigens and clinical risk factors for liver metastasis of colorectal cancer: a predictive panel.Dis Colon Rectum. 2010 Jan;53(1):31-8. doi: 10.1007/DCR.0b013e3181bdca3a.
• [1384] High expression of partitioning defective 3-like protein is associated with malignancy in colorectal cancer.Tumour Biol. 2017 Apr;39(4):1010428317698393. doi: 10.1177/1010428317698393.
• [1385] Epigenetic silencing of protocadherin 10 in colorectal cancer.Oncol Lett. 2017 Apr;13(4):2449-2453. doi: 10.3892/ol.2017.5733. Epub 2017 Feb 13.
• [1386] Decreased CK1 expression predicts prolonged survival in colorectal cancer patients.Tumour Biol. 2016 Jul;37(7):8731-9. doi: 10.1007/s13277-015-4745-8. Epub 2016 Jan 7.
• [1387] A Novel Prognostic DNA Methylation Panel for Colorectal Cancer.Int J Mol Sci. 2019 Sep 20;20(19):4672. doi: 10.3390/ijms20194672.
• [1388] Glucuronorhamnoxylan from Capsosiphon fulvescens inhibits the growth of HT-29 human colon cancer cells in vitro and in vivo via induction of apoptotic cell death.Int J Biol Macromol. 2019 Mar 1;124:1060-1068. doi: 10.1016/j.ijbiomac.2018.12.001. Epub 2018 Dec 3.
• [1389] PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway.Oncol Rep. 2019 Jan;41(1):43-56. doi: 10.3892/or.2018.6825. Epub 2018 Oct 25.
• [1390] Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells.Mol Cell Proteomics. 2011 Oct;10(10):M110.005397. doi: 10.1074/mcp.M110.005397. Epub 2011 May 27.
• [1391] Comprehensive analysis of the long noncoding RNA expression profile and construction of the lncRNA-mRNA co-expression network in colorectal cancer.Cancer Biol Ther. 2020;21(2):157-169. doi: 10.1080/15384047.2019.1673098. Epub 2019 Oct 16.
• [1392] MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway.EBioMedicine. 2019 May;43:270-281. doi: 10.1016/j.ebiom.2019.04.010. Epub 2019 Apr 12.
• [1393] Significance of PITX2 Promoter Methylation in Colorectal Carcinoma Prognosis.Clin Colorectal Cancer. 2018 Jun;17(2):e385-e393. doi: 10.1016/j.clcc.2018.02.008. Epub 2018 Feb 23.
• [1394] Expression of cytosolic and group X secretory phospholipase A(2) genes in human colorectal adenocarcinomas.Cancer Lett. 2002 Aug 28;182(2):175-82. doi: 10.1016/s0304-3835(02)00081-2.
• [1395] NFATC3-PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines.Cancer Res Treat. 2019 Jan;51(1):391-401. doi: 10.4143/crt.2018.103. Epub 2018 Jun 14.
• [1396] Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue.PLoS One. 2015 Apr 22;10(4):e0123902. doi: 10.1371/journal.pone.0123902. eCollection 2015.
• [1397] EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway.Cancer Res. 2019 May 1;79(9):2257-2270. doi: 10.1158/0008-5472.CAN-18-3238. Epub 2019 Mar 12.
• [1398] Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo.Oncotarget. 2018 Apr 10;9(27):19192-19202. doi: 10.18632/oncotarget.24953. eCollection 2018 Apr 10.
• [1399] Weighted gene coexpression analysis indicates that PLAGL2 and POFUT1 are related to the differential features of proximal and distal colorectal cancer.Oncol Rep. 2019 Dec;42(6):2473-2485. doi: 10.3892/or.2019.7368. Epub 2019 Oct 14.
• [1400] Expression and Clinical Significance of POLR1D in Colorectal Cancer.Oncology. 2020;98(3):138-145. doi: 10.1159/000504174. Epub 2019 Nov 13.
• [1401] Tubeimoside-I sensitizes colorectal cancer cells to chemotherapy by inducing ROS-mediated impaired autophagolysosomes accumulation.J Exp Clin Cancer Res. 2019 Aug 14;38(1):353. doi: 10.1186/s13046-019-1355-0.
• [1402] PPP1R3 gene (protein phosphatase 1) alterations in colorectal cancer and its relationship to metastasis.Oncol Rep. 2005 Jun;13(6):1223-7.
• [1403] MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer.Cell Death Dis. 2015 Aug 6;6(8):e1845. doi: 10.1038/cddis.2015.200.
• [1404] B55-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.Cancer Cell. 2010 Nov 16;18(5):459-71. doi: 10.1016/j.ccr.2010.10.021.
• [1405] Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer.Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3086-96. doi: 10.1158/1055-9965.EPI-09-0289. Epub 2009 Oct 20.
• [1406] Human trypsinogen in colorectal cancer.Int J Cancer. 2001 Jul 1;93(1):67-73. doi: 10.1002/ijc.1304.
• [1407] Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.Oncol Lett. 2018 Jun;15(6):8796-8804. doi: 10.3892/ol.2018.8387. Epub 2018 Mar 29.
• [1408] Effectiveness of gene expression profiling for response prediction of rectal cancer to preoperative radiotherapy.J Gastroenterol. 2007 Sep;42(9):730-6. doi: 10.1007/s00535-007-2089-x. Epub 2007 Sep 25.
• [1409] RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer.Int J Cancer. 2019 Oct 15;145(8):2209-2224. doi: 10.1002/ijc.32338. Epub 2019 Apr 30.
• [1410] RANBP9 suppresses tumor proliferation in colorectal cancer.Oncol Lett. 2019 May;17(5):4409-4416. doi: 10.3892/ol.2019.10134. Epub 2019 Mar 8.
• [1411] Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression.Gastroenterology. 2009 Jan;136(1):206-16. doi: 10.1053/j.gastro.2008.09.063. Epub 2008 Oct 2.
• [1412] IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway.Cancer Manag Res. 2018 Dec 31;11:369-378. doi: 10.2147/CMAR.S186236. eCollection 2019.
• [1413] The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor.Cancer Genomics Proteomics. 2010 Mar-Apr;7(2):75-80.
• [1414] Downregulation of microRNA?83?p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin?/Wnt/catenin signaling pathway.Mol Med Rep. 2019 May;19(5):4475-4483. doi: 10.3892/mmr.2019.10059. Epub 2019 Mar 19.
• [1415] Mutational and expressional analysis of RFC3, a clamp loader in DNA replication, in gastric and colorectal cancers.Hum Pathol. 2010 Oct;41(10):1431-7. doi: 10.1016/j.humpath.2010.03.006. Epub 2010 Jun 22.
• [1416] Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair.Clin Cancer Res. 2019 Jul 15;25(14):4567-4579. doi: 10.1158/1078-0432.CCR-18-3735. Epub 2019 Apr 12.
• [1417] Lack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes.Int J Cancer. 2010 Aug 15;127(4):889-98. doi: 10.1002/ijc.25106.
• [1418] MicroRNA-193a and taxol combination: A new strategy for treatment of colorectal cancer.J Cell Biochem. 2020 Feb;121(2):1388-1399. doi: 10.1002/jcb.29374. Epub 2019 Sep 12.
• [1419] Analysis of RIN1 gene expression in colorectal cancer.Oncol Rep. 2007 May;17(5):1171-5.
• [1420] Circulating MIC-1/GDF15 is a complementary screening biomarker with CEA and correlates with liver metastasis and poor survival in colorectal cancer.Oncotarget. 2017 Apr 11;8(15):24892-24901. doi: 10.18632/oncotarget.15279.
• [1421] Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM.Carcinogenesis. 2010 Mar;31(3):442-5. doi: 10.1093/carcin/bgp293. Epub 2009 Nov 27.
• [1422] Loss of RNF40 Decreases NF-B Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice.J Crohns Colitis. 2019 Mar 26;13(3):362-373. doi: 10.1093/ecco-jcc/jjy165.
• [1423] KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation.Mol Carcinog. 2017 Mar;56(3):1068-1081. doi: 10.1002/mc.22572. Epub 2016 Oct 26.
• [1424] Development of a multiplexed tumor-associated autoantibody-based blood test for the detection of colorectal cancer.Clin Chim Acta. 2017 Dec;475:157-163. doi: 10.1016/j.cca.2017.10.022. Epub 2017 Oct 23.
• [1425] Role of ribosomal protein mutations in tumor development (Review).Int J Oncol. 2016 Apr;48(4):1313-24. doi: 10.3892/ijo.2016.3387. Epub 2016 Feb 9.
• [1426] Nucleotide and deduced amino acid sequence of human ribosomal protein L18.Biochim Biophys Acta. 1993 Oct 19;1216(1):134-6. doi: 10.1016/0167-4781(93)90050-n.
• [1427] Faecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer.J Cell Mol Med. 2008 Oct;12(5B):1936-43. doi: 10.1111/j.1582-4934.2008.00253.x. Epub 2008 Feb 4.
• [1428] RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.PLoS One. 2019 Oct 3;14(10):e0222392. doi: 10.1371/journal.pone.0222392. eCollection 2019.
• [1429] Ribosomal protein L7a gene is up-regulated but not fused to the tyrosine kinase receptor as chimeric trk oncogene in human colorectal carcinoma.Int J Oncol. 2000 Apr;16(4):757-62. doi: 10.3892/ijo.16.4.757.
• [1430] Ubiquitin-ribosomal protein S27a gene overexpressed in human colorectal carcinoma is an early growth response gene.Cancer Res. 1993 Apr 15;53(8):1916-20.
• [1431] Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.World J Gastroenterol. 2004 Dec 1;10(23):3441-54. doi: 10.3748/wjg.v10.i23.3441.
• [1432] Meat, starch and non-starch polysaccharides, are epidemiological and experimental findings consistent with acquired genetic alterations in sporadic colorectal cancer?.Cancer Lett. 1997 Mar 19;114(1-2):25-34. doi: 10.1016/s0304-3835(97)04618-1.
• [1433] iTRAQ-based proteomic analysis of DMH-induced colorectal cancer in mice reveals the expressions of -catenin, decorin, septin-7, and S100A10 expression in 53 cases of human hereditary polyposis colorectal cancer.Clin Transl Oncol. 2019 Feb;21(2):220-231. doi: 10.1007/s12094-018-1912-6. Epub 2018 Jun 28.
• [1434] Alteration of the tumor suppressor SARDH in sporadic colorectal cancer: A functional and transcriptome profiling-based study.Mol Carcinog. 2019 Jun;58(6):957-966. doi: 10.1002/mc.22984. Epub 2019 Mar 5.
• [1435] SCRN1 is a novel marker for prognosis in colorectal cancer.J Surg Oncol. 2010 Feb 1;101(2):156-9. doi: 10.1002/jso.21459.
• [1436] Pancreatitis-associated protein is related closely to neoplastic proliferative activity in patients with colorectal carcinoma.Anat Rec (Hoboken). 2009 Feb;292(2):249-53. doi: 10.1002/ar.20806.
• [1437] Genetic variants in selenoprotein genes increase risk of colorectal cancer.Carcinogenesis. 2010 Jun;31(6):1074-9. doi: 10.1093/carcin/bgq076. Epub 2010 Apr 8.
• [1438] ROR1-AS1 promotes tumorigenesis of colorectal cancer via targeting Wnt/-catenin.Eur Rev Med Pharmacol Sci. 2019 Aug;23(3 Suppl):217-223. doi: 10.26355/eurrev_201908_18650.
• [1439] Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers.Cancer Res. 2005 Jun 1;65(11):4607-13. doi: 10.1158/0008-5472.CAN-05-0165.
• [1440] Characterization of tissue- and cell-type-specific expression of a novel human septin family gene, Bradeion.Biochem Biophys Res Commun. 2001 Aug 24;286(3):547-53. doi: 10.1006/bbrc.2001.5413.
• [1441] Chromosomal localization of the human urokinase plasminogen activator receptor and plasminogen activator inhibitor type-2 genes: implications in colorectal cancer.J Gastroenterol Hepatol. 1994 Jul-Aug;9(4):340-3. doi: 10.1111/j.1440-1746.1994.tb01252.x.
• [1442] MMP-7 and SGCE as distinctive molecular factors in sporadic colorectal cancers from the mutator phenotype pathway.Int J Oncol. 2010 May;36(5):1209-15. doi: 10.3892/ijo_00000604.
• [1443] High expression of SHMT2 is correlated with tumor progression and predicts poor prognosis in gastrointestinal tumors.Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9379-9392. doi: 10.26355/eurrev_201911_19431.
• [1444] Overexpression of the small transmembrane and glycosylated protein SMAGP supports metastasis formation of a rat pancreatic adenocarcinoma line.Int J Cancer. 2005 Dec 20;117(6):913-22. doi: 10.1002/ijc.21275.
• [1445] E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer.Cancer Manag Res. 2019 Feb 22;11:1795-1803. doi: 10.2147/CMAR.S178111. eCollection 2019.
• [1446] Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease.Oncol Rep. 2010 Feb;23(2):429-36.
• [1447] Genetic variants in m6A modification genes are associated with colorectal cancer risk.Carcinogenesis. 2020 Mar 13;41(1):8-17. doi: 10.1093/carcin/bgz165.
• [1448] miR-885-5p upregulation promotes colorectal cancer cell proliferation and migration by targeting suppressor of cytokine signaling.Oncol Lett. 2018 Jul;16(1):65-72. doi: 10.3892/ol.2018.8645. Epub 2018 May 7.
• [1449] Identification of potential genes/proteins regulated by Tiam1 in colorectal cancer by microarray analysis and proteome analysis.Cell Biol Int. 2008 Oct;32(10):1215-22. doi: 10.1016/j.cellbi.2008.07.004. Epub 2008 Jul 16.
• [1450] Association and diagnostic value of serum SPINK4 in colorectal cancer.PeerJ. 2019 Apr 4;7:e6679. doi: 10.7717/peerj.6679. eCollection 2019.
• [1451] Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.J Exp Clin Cancer Res. 2019 Sep 13;38(1):405. doi: 10.1186/s13046-019-1389-3.
• [1452] Conserved expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin in human colorectal carcinomas.Cancer Lett. 2000 Feb 1;148(2):127-34. doi: 10.1016/s0304-3835(99)00322-5.
• [1453] Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer.PLoS One. 2019 Mar 11;14(3):e0213411. doi: 10.1371/journal.pone.0213411. eCollection 2019.
• [1454] Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.Lab Invest. 1998 Jul;78(7):797-811.
• [1455] LncRNA ST3Gal6-AS1/ST3Gal6 axis mediates colorectal cancer progression by regulating -2,3 sialylation via PI3K/Akt signaling.Int J Cancer. 2019 Jul 15;145(2):450-460. doi: 10.1002/ijc.32103. Epub 2019 Jan 20.
• [1456] Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.Br J Cancer. 2009 Aug 4;101(3):483-91. doi: 10.1038/sj.bjc.6605144.
• [1457] Detection of Tn, sialosyl-Tn and T antigens in hereditary nonpolyposis colorectal cancer.Virchows Arch. 1996 Dec;429(6):345-52. doi: 10.1007/BF00198438.
• [1458] A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment.J Transl Med. 2011 May 28;9:82. doi: 10.1186/1479-5876-9-82.
• [1459] The Oncogenic Potential of SUV39H2: A Comprehensive and Perspective View.J Cancer. 2019 Jan 1;10(3):721-729. doi: 10.7150/jca.28254. eCollection 2019.
• [1460] Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability.Oncogene. 2002 Aug 1;21(33):5081-7. doi: 10.1038/sj.onc.1205703.
• [1461] A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer.BMC Med Genet. 2010 Jun 9;11:88. doi: 10.1186/1471-2350-11-88.
• [1462] Natural Killer Cell IFN Secretion is Profoundly Suppressed Following Colorectal Cancer Surgery.Ann Surg Oncol. 2018 Nov;25(12):3747-3754. doi: 10.1245/s10434-018-6691-3. Epub 2018 Sep 5.
• [1463] TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells.Biochem Biophys Res Commun. 2017 Jun 3;487(3):716-722. doi: 10.1016/j.bbrc.2017.04.123. Epub 2017 Apr 25.
• [1464] Th17 cytokine profiling of colorectal cancer patients with or without enterovirus 71 antigen expression.Cytokine. 2018 Jul;107:35-42. doi: 10.1016/j.cyto.2017.11.012. Epub 2017 Nov 23.
• [1465] MicroRNA-302c represses epithelial-mesenchymal transition and metastasis by targeting transcription factor AP-4 in colorectal cancer.Biomed Pharmacother. 2018 Sep;105:670-676. doi: 10.1016/j.biopha.2018.06.025. Epub 2018 Jun 12.
• [1466] Long non-coding RNA DILC suppresses bladder cancer cells progression.Gene. 2019 Aug 20;710:193-201. doi: 10.1016/j.gene.2019.06.009. Epub 2019 Jun 7.
• [1467] Suppression of neurotensin receptor type 1 expression and function by histone deacetylase inhibitors in human colorectal cancers.Mol Cancer Ther. 2010 Aug;9(8):2389-98. doi: 10.1158/1535-7163.MCT-09-1080. Epub 2010 Jul 27.
• [1468] Epigenetic profiling and mRNA expression reveal candidate genes as biomarkers for colorectal cancer.J Cell Biochem. 2019 Jun;120(6):10767-10776. doi: 10.1002/jcb.28368. Epub 2019 Jan 22.
• [1469] Higher plasma concentration of TP53-induced glycolysis and apoptosis regulator is associated with a lower risk of colorectal cancer metastasis.Cancer Manag Res. 2018 Dec 24;11:263-272. doi: 10.2147/CMAR.S190272. eCollection 2019.
• [1470] miR-206 regulates 5-FU resistance by targeting Bcl-2 in colon cancer cells.Onco Targets Ther. 2018 Mar 29;11:1757-1765. doi: 10.2147/OTT.S159093. eCollection 2018.
• [1471] CAC1 knockdown reverses drug resistance through the downregulation of P-gp and MRP-1 expression in colorectal cancer.PLoS One. 2019 Sep 10;14(9):e0222035. doi: 10.1371/journal.pone.0222035. eCollection 2019.
• [1472] Autoinducer-2 of gut microbiota, a potential novel marker for human colorectal cancer, is associated with the activation of TNFSF9 signaling in macrophages.Oncoimmunology. 2019 Jun 10;8(10):e1626192. doi: 10.1080/2162402X.2019.1626192. eCollection 2019.
• [1473] Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers.J Pathol. 2010 Jun;221(2):139-46. doi: 10.1002/path.2683.
• [1474] Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas.PLoS Biol. 2019 Aug 28;17(8):e3000425. doi: 10.1371/journal.pbio.3000425. eCollection 2019 Aug.
• [1475] Presence of activating KRAS mutations correlates significantly with expression of tumour suppressor genes DCN and TPM1 in colorectal cancer.BMC Cancer. 2009 Aug 13;9:282. doi: 10.1186/1471-2407-9-282.
• [1476] TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4.J Exp Clin Cancer Res. 2019 Apr 12;38(1):159. doi: 10.1186/s13046-019-1143-x.
• [1477] Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8.Genes Chromosomes Cancer. 2004 Jul;40(3):247-60. doi: 10.1002/gcc.20039.
• [1478] TSPAN8 promotes colorectal cancer cell growth and migration in LSD1-dependent manner.Life Sci. 2020 Jan 15;241:117114. doi: 10.1016/j.lfs.2019.117114. Epub 2019 Nov 29.
• [1479] Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31.
• [1480] Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway.PLoS One. 2011;6(5):e20276. doi: 10.1371/journal.pone.0020276. Epub 2011 May 24.
• [1481] Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer.Oncology. 2005;68(2-3):246-55. doi: 10.1159/000086781. Epub 2005 Jul 7.
• [1482] A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.Br J Cancer. 2011 Sep 6;105(6):870-5. doi: 10.1038/bjc.2011.296. Epub 2011 Aug 2.
• [1483] An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer.Int J Cancer. 2011 Mar 1;128(5):1018-30. doi: 10.1002/ijc.25419.
• [1484] Genomic and epigenomic integration identifies a prognostic signature in colon cancer.Clin Cancer Res. 2011 Mar 15;17(6):1535-45. doi: 10.1158/1078-0432.CCR-10-2509. Epub 2011 Jan 28.
• [1485] Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins.BMC Cancer. 2011 Aug 5;11:339. doi: 10.1186/1471-2407-11-339.
• [1486] Methylation of the homeobox gene, HOPX, is frequently detected in poorly differentiated colorectal cancer.Anticancer Res. 2011 Sep;31(9):2889-92.
• [1487] KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis.Clin Cancer Res. 2011 Jun 1;17(11):3558-68. doi: 10.1158/1078-0432.CCR-10-2729. Epub 2011 Apr 29.
• [1488] NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.Cell Cycle. 2011 Oct 1;10(19):3284-99. doi: 10.4161/cc.10.19.17176. Epub 2011 Oct 1.
• [1489] The emerging role for Cullin 4 family of E3 ligases in tumorigenesis.Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):138-159. doi: 10.1016/j.bbcan.2018.11.007. Epub 2018 Dec 30.
• [1490] Methyl-CpG binding column-based identification of nine genes hypermethylated in colorectal cancer.Mol Carcinog. 2011 Nov;50(11):846-56. doi: 10.1002/mc.20763. Epub 2011 Mar 22.
• [1491] Kinesin 18A expression: clinical relevance to colorectal cancer progression.Int J Cancer. 2011 Dec 1;129(11):2543-52. doi: 10.1002/ijc.25916. Epub 2011 Jun 9.
• [1492] Prognostic significance of the detection of peripheral blood CEACAM5mRNA-positive cells by real-time polymerase chain reaction in operable colorectal cancer.Clin Cancer Res. 2011 Jan 1;17(1):165-73. doi: 10.1158/1078-0432.CCR-10-0565. Epub 2010 Nov 11.
• [1493] Clinical and economic aspects of KRAS mutational status as predictor for epidermal growth factor receptor inhibitor therapy in metastatic colorectal cancer patients.Oncology. 2011;81(5-6):359-64. doi: 10.1159/000334919. Epub 2012 Jan 13.
• [1494] A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.Int J Cancer. 2011 Mar 1;128(5):1069-79. doi: 10.1002/ijc.25453.
• [1495] Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors.Mol Carcinog. 2011 Jan;50(1):8-15. doi: 10.1002/mc.20692.
• [1496] RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression.Theranostics. 2019 Jun 2;9(12):3659-3673. doi: 10.7150/thno.32126. eCollection 2019.
• [1497] Enhancement of TGF- signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.Cancer Res. 2011 Oct 15;71(20):6438-49. doi: 10.1158/0008-5472.CAN-11-1645.
• [1498] Clinical validation of colorectal cancer biomarkers identified from bioinformatics analysis of public expression data.Clin Cancer Res. 2011 Feb 15;17(4):700-9. doi: 10.1158/1078-0432.CCR-10-1300. Epub 2011 Feb 8.
• [1499] Tumor-targeted delivery of TAT-Apoptin fusion gene using Escherichia coli Nissle 1917 to colorectal cancer.Med Hypotheses. 2011 Apr;76(4):533-4. doi: 10.1016/j.mehy.2010.12.010. Epub 2011 Jan 21.
• [1500] Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.Chronobiol Int. 2011 Dec;28(10):841-51. doi: 10.3109/07420528.2011.615182.
• [1501] Long non-coding RNA AK001058 regulates tumor growth and angiogenesis in colorectal cancer via methylation of ADAMTS12.Am J Transl Res. 2019 Sep 15;11(9):6117-6123. eCollection 2019.
• [1502] AGR3 promotes the stemness of colorectal cancer via modulating Wnt/-catenin signalling.Cell Signal. 2020 Jan;65:109419. doi: 10.1016/j.cellsig.2019.109419. Epub 2019 Sep 14.
• [1503] Potential role of annexin A7 in cancers.Clin Chim Acta. 2013 Aug 23;423:83-9. doi: 10.1016/j.cca.2013.04.018. Epub 2013 Apr 29.
• [1504] Weichang'an suppressed migration and invasion of HCT116 cells by inhibiting Wnt/-catenin pathway while upregulating ARHGAP25.Biotechnol Appl Biochem. 2019 Sep;66(5):787-793. doi: 10.1002/bab.1784. Epub 2019 Aug 19.
• [1505] SNHG14 stimulates cell autophagy to facilitate cisplatin resistance of colorectal cancer by regulating miR-186/ATG14 axis.Biomed Pharmacother. 2020 Jan;121:109580. doi: 10.1016/j.biopha.2019.109580. Epub 2019 Nov 5.
• [1506] Identification of candidate genes and long non-coding RNAs associated with the effect of ATP5J in colorectal cancer.Int J Oncol. 2018 Apr;52(4):1129-1138. doi: 10.3892/ijo.2018.4281. Epub 2018 Feb 22.
• [1507] Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer.BMC Cancer. 2018 Aug 6;18(1):793. doi: 10.1186/s12885-018-4657-2.
• [1508] MiR-760 suppresses human colorectal cancer growth by targeting BATF3/AP-1/cyclinD1 signaling.J Exp Clin Cancer Res. 2018 Apr 16;37(1):83. doi: 10.1186/s13046-018-0757-8.
• [1509] Celecoxib enhances the radiosensitivity of HCT116 cells in a COX-2 independent manner by up-regulating BCCIP.Am J Transl Res. 2017 Mar 15;9(3):1088-1100. eCollection 2017.
• [1510] Natural killer cells inhibit oxaliplatin-resistant colorectal cancer by repressing WBSCR22 via upregulating microRNA-146b-5p.Am J Cancer Res. 2018 May 1;8(5):824-834. eCollection 2018.
• [1511] Capn4 promotes colorectal cancer cell proliferation by increasing MAPK7 through activation of the Wnt/-Catenin pathway.Exp Cell Res. 2018 Feb 15;363(2):235-242. doi: 10.1016/j.yexcr.2018.01.013. Epub 2018 Jan 10.
• [1512] The Role of Adaptor Protein CARD9 in Colitis-Associated Cancer.Mol Ther Oncolytics. 2019 Aug 30;15:1-6. doi: 10.1016/j.omto.2019.08.007. eCollection 2019 Dec 20.
• [1513] RET fusions observed in lung and colorectal cancers are sensitive to ponatinib.Oncotarget. 2018 Jul 3;9(51):29654-29664. doi: 10.18632/oncotarget.25664. eCollection 2018 Jul 3.
• [1514] Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells.Oncotarget. 2017 Apr 18;8(16):26231-26244. doi: 10.18632/oncotarget.15439.
• [1515] Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt.Oncotarget. 2019 Jul 23;10(45):4630-4639. doi: 10.18632/oncotarget.27050. eCollection 2019 Jul 23.
• [1516] Over-expression of Nav1.6 channels is associated with lymph node metastases in colorectal cancer.World J Surg Oncol. 2019 Oct 31;17(1):175. doi: 10.1186/s12957-019-1715-4.
• [1517] Screening key genes and signaling pathways in colorectal cancer by integrated bioinformatics analysis.Mol Med Rep. 2019 Aug;20(2):1259-1269. doi: 10.3892/mmr.2019.10336. Epub 2019 Jun 4.
• [1518] CDCA3 promotes cell proliferation by activating the NF-B/cyclin D1 signaling pathway in colorectal cancer.Biochem Biophys Res Commun. 2018 Jun 2;500(2):196-203. doi: 10.1016/j.bbrc.2018.04.034. Epub 2018 Apr 14.
• [1519] Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway.Oncogenesis. 2019 Feb 26;8(3):19. doi: 10.1038/s41389-019-0123-5.
• [1520] Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21(Wif1/Cip1) in Colorectal Cancer Cells.Medchemcomm. 2018;9(1):87-99. doi: 10.1039/C7MD00393E. Epub 2017 Nov 3.
• [1521] CHST7 Gene Methylation and Sex-Specific Effects on Colorectal Cancer Risk.Dig Dis Sci. 2019 Aug;64(8):2158-2166. doi: 10.1007/s10620-019-05530-9. Epub 2019 Feb 28.
• [1522] Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.Med Sci Monit. 2019 Jun 5;25:4176-4185. doi: 10.12659/MSM.914195.
• [1523] SCF/C-Kit/JNK/AP-1 Signaling Pathway Promotes Claudin-3 Expression in Colonic Epithelium and Colorectal Carcinoma.Int J Mol Sci. 2017 Apr 6;18(4):765. doi: 10.3390/ijms18040765.
• [1524] Analysis of Colorectal Cancer-Associated Alternative Splicing Based on Transcriptome.DNA Cell Biol. 2020 Jan;39(1):16-24. doi: 10.1089/dna.2019.5111. Epub 2019 Dec 5.
• [1525] MicroRNA-4461 derived from bone marrow mesenchymal stem cell exosomes inhibits tumorigenesis by downregulating COPB2 expression in colorectal cancer.Biosci Biotechnol Biochem. 2020 Feb;84(2):338-346. doi: 10.1080/09168451.2019.1677452. Epub 2019 Oct 21.
• [1526] Prognostic Significance of CSN2, CD8, and MMR Status-Associated Nomograms in Patients with Colorectal Cancer.Transl Oncol. 2018 Oct;11(5):1202-1212. doi: 10.1016/j.tranon.2018.07.006. Epub 2018 Jul 31.
• [1527] Long Non-Coding RNA SH3PXD2A-AS1 Promotes Cell Progression Partly Through Epigenetic Silencing P57 and KLF2 in Colorectal Cancer.Cell Physiol Biochem. 2018;46(6):2197-2214. doi: 10.1159/000489589. Epub 2018 May 3.
• [1528] LncRNA SUMO1P3 promotes proliferation and inhibits apoptosis in colorectal cancer by epigenetically silencing CPEB3.Biochem Biophys Res Commun. 2019 Apr 2;511(2):239-245. doi: 10.1016/j.bbrc.2019.02.006. Epub 2019 Feb 22.
• [1529] Cleavage and polyadenylation specific factor 4 promotes colon cancer progression by transcriptionally activating hTERT.Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1533-1543. doi: 10.1016/j.bbamcr.2019.07.001. Epub 2019 Jul 10.
• [1530] Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes.Int J Cancer. 2018 Dec 1;143(11):2800-2813. doi: 10.1002/ijc.31725. Epub 2018 Oct 3.
• [1531] Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease.Cell Mol Life Sci. 2019 Sep;76(18):3515-3523. doi: 10.1007/s00018-019-03137-x. Epub 2019 May 14.
• [1532] Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents.Oncol Res. 2018 Dec 27;27(1):29-38. doi: 10.3727/096504018X15179694020751. Epub 2018 Feb 9.
• [1533] MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation.Mol Carcinog. 2018 Oct;57(10):1421-1431. doi: 10.1002/mc.22868. Epub 2018 Jul 12.
• [1534] The Differential Expression of Core Genes in Nucleotide Excision Repair Pathway Indicates Colorectal Carcinogenesis and Prognosis.Biomed Res Int. 2018 Jan 15;2018:9651320. doi: 10.1155/2018/9651320. eCollection 2018.
• [1535] MicroRNA-498 reduces the proliferation and invasion of colorectal cancer cells via targeting Bcl-2.FEBS Open Bio. 2020 Jan;10(1):168-175. doi: 10.1002/2211-5463.12767. Epub 2019 Dec 17.
• [1536] Prognostic value of DLGAP5 in colorectal cancer.Int J Colorectal Dis. 2019 Aug;34(8):1455-1465. doi: 10.1007/s00384-019-03339-6. Epub 2019 Jul 8.
• [1537] MicroRNA-24 regulates the growth and chemosensitivity of the human colorectal cancer cells by targeting RNA-binding protein DND1.J BUON. 2019 Jul-Aug;24(4):1476-1481.
• [1538] Co-inhibition of BET proteins and NF-B as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions.Cell Death Dis. 2018 Feb 22;9(3):315. doi: 10.1038/s41419-018-0354-y.
• [1539] Overexpression of dedicator of cytokinesis 2 correlates with good prognosis in colorectal cancer associated with more prominent CD8(+) lymphocytes infiltration: a colorectal cancer analysis.J Cell Biochem. 2018 Nov;119(11):8962-8970. doi: 10.1002/jcb.27151. Epub 2018 Aug 4.
• [1540] The protective role of all-transretinoic acid (ATRA) against colorectal cancer development is achieved via increasing miR-3666 expression and decreasing E2F7 expression.Biomed Pharmacother. 2018 Aug;104:94-101. doi: 10.1016/j.biopha.2018.05.015. Epub 2018 May 14.
• [1541] H3K27 acetylation-induced lncRNA EIF3J-AS1 improved proliferation and impeded apoptosis of colorectal cancer through miR-3163/YAP1 axis.J Cell Biochem. 2020 Feb;121(2):1923-1933. doi: 10.1002/jcb.29427. Epub 2019 Nov 11.
• [1542] Comprehensive characterization of the rRNA metabolism-related genes in human cancer.Oncogene. 2020 Jan;39(4):786-800. doi: 10.1038/s41388-019-1026-9. Epub 2019 Sep 23.
• [1543] Serum FBLN1 and STK31 as biomarkers of colorectal cancer and their ability to noninvasively differentiate colorectal cancer from benign polyps.Clin Chim Acta. 2018 Aug;483:151-155. doi: 10.1016/j.cca.2018.04.038. Epub 2018 Apr 30.
• [1544] Long noncoding RNA FEZF1-AS1 in human cancers.Clin Chim Acta. 2019 Oct;497:20-26. doi: 10.1016/j.cca.2019.07.004. Epub 2019 Jul 2.
• [1545] Multiple rounds of one sample versus two sample faecal immunochemical test-based colorectal cancer screening: a population-based study.Lancet Gastroenterol Hepatol. 2019 Aug;4(8):622-631. doi: 10.1016/S2468-1253(19)30176-1. Epub 2019 Jun 10.
• [1546] Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.World J Gastroenterol. 2018 Sep 14;24(34):3884-3897. doi: 10.3748/wjg.v24.i34.3884.
• [1547] FOXF1 Induces Epithelial-Mesenchymal Transition in Colorectal Cancer Metastasis by Transcriptionally Activating SNAI1.Neoplasia. 2018 Oct;20(10):996-1007. doi: 10.1016/j.neo.2018.08.004. Epub 2018 Sep 10.
• [1548] Elevated expression of Gab1 promotes breast cancer metastasis by dissociating the PAR complex.J Exp Clin Cancer Res. 2019 Jan 21;38(1):27. doi: 10.1186/s13046-019-1025-2.
• [1549] Prognostic Stratification of Advanced Gastric Signet Ring Cell Carcinoma by Clinicopathological Factors and GALNT14 Genotype.J Cancer. 2018 Sep 8;9(19):3540-3547. doi: 10.7150/jca.26293. eCollection 2018.
• [1550] Guanylate-binding protein-2 inhibits colorectal cancer cell growth and increases the sensitivity to paclitaxel of paclitaxel-resistant colorectal cancer cells by interfering Wnt signaling.J Cell Biochem. 2020 Feb;121(2):1250-1259. doi: 10.1002/jcb.29358. Epub 2019 Sep 6.
• [1551] Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway.J Transl Med. 2018 Jun 4;16(1):150. doi: 10.1186/s12967-018-1530-7.
• [1552] Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.EMBO Mol Med. 2018 Nov;10(11):e8699. doi: 10.15252/emmm.201708699.
• [1553] Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.J Hematol Oncol. 2018 Jul 17;11(1):95. doi: 10.1186/s13045-018-0638-9.
• [1554] LncRNA HAND2-AS1 inhibits 5-fluorouracil resistance by modulating miR-20a/PDCD4 axis in colorectal cancer.Cell Signal. 2020 Feb;66:109483. doi: 10.1016/j.cellsig.2019.109483. Epub 2019 Nov 21.
• [1555] Ginkgo biloba extract 761 enhances 5-fluorouracil chemosensitivity in colorectal cancer cells through regulation of high mobility group-box 3 expression.Am J Transl Res. 2018 Jun 15;10(6):1773-1783. eCollection 2018.
• [1556] Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression.Cancer Cell Int. 2018 Jan 23;18:11. doi: 10.1186/s12935-018-0506-2. eCollection 2018.
• [1557] HNRNPLL, a newly identified colorectal cancer metastasis suppressor, modulates alternative splicing of CD44 during epithelial-mesenchymal transition.Gut. 2018 Jun;67(6):1103-1111. doi: 10.1136/gutjnl-2016-312927. Epub 2017 Mar 30.
• [1558] Study of Promoter Methylation Patterns of HOXA2, HOXA5, and HOXA6 and Its Clinicopathological Characteristics in Colorectal Cancer.Front Oncol. 2019 May 21;9:394. doi: 10.3389/fonc.2019.00394. eCollection 2019.
• [1559] The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer.J Gastroenterol Hepatol. 2019 Oct;34(10):1766-1776. doi: 10.1111/jgh.14660. Epub 2019 Apr 10.
• [1560] Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/-catenin signaling in colorectal cancer cells.Oncogene. 2019 Aug;38(32):6051-6064. doi: 10.1038/s41388-019-0856-9. Epub 2019 Jul 10.
• [1561] Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi-associated microtubules.Cancer Sci. 2019 Apr;110(4):1306-1316. doi: 10.1111/cas.13970. Epub 2019 Feb 28.
• [1562] A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer.BMC Gastroenterol. 2019 Jul 24;19(1):131. doi: 10.1186/s12876-019-1047-4.
• [1563] Interleukin-38 in colorectal cancer: a potential role in precision medicine.Cancer Immunol Immunother. 2020 Jan;69(1):69-79. doi: 10.1007/s00262-019-02440-7. Epub 2019 Nov 30.
• [1564] BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis.Cancer Sci. 2017 Jun;108(6):1135-1143. doi: 10.1111/cas.13234. Epub 2017 Jun 2.
• [1565] A miR-124/ITGA3 axis contributes to colorectal cancer metastasis by regulating anoikis susceptibility.Biochem Biophys Res Commun. 2018 Jun 27;501(3):758-764. doi: 10.1016/j.bbrc.2018.05.062. Epub 2018 May 18.
• [1566] Circ-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation.Cancer Manag Res. 2019 Jul 12;11:6499-6509. doi: 10.2147/CMAR.S203137. eCollection 2019.
• [1567] Immunohistochemistry is a feasible method to screen BRAF V600E mutation in colorectal and papillary thyroid carcinoma.Exp Mol Pathol. 2018 Aug;105(1):153-159. doi: 10.1016/j.yexmp.2018.07.006. Epub 2018 Jul 19.
• [1568] The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferation.Cancer Cell Int. 2019 May 22;19:144. doi: 10.1186/s12935-019-0841-y. eCollection 2019.
• [1569] Enhanced expression of KIF4A in colorectal cancer is associated with lymph node metastasis.Oncol Lett. 2018 Feb;15(2):2188-2194. doi: 10.3892/ol.2017.7555. Epub 2017 Dec 8.
• [1570] LncRNA TTN-AS1 sponges miR-376a-3p to promote colorectal cancer progression via upregulating KLF15.Life Sci. 2020 Mar 1;244:116936. doi: 10.1016/j.lfs.2019.116936. Epub 2019 Oct 11.
• [1571] Identification of Potential Key Genes and Pathways in Early-Onset Colorectal Cancer Through Bioinformatics Analysis.Cancer Control. 2019 Jan-Dec;26(1):1073274819831260. doi: 10.1177/1073274819831260.
• [1572] Exposure to asbestos and the risk of colorectal cancer mortality: a systematic review and meta-analysis.Occup Environ Med. 2019 Nov;76(11):861-871. doi: 10.1136/oemed-2019-105735. Epub 2019 Oct 8.
• [1573] LYPD8 regulates the proliferation and migration of colorectal cancer cells through inhibiting the secretion of IL? and TNF?"Xu J. Zhang W
• [1574] MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.Mol Oncol. 2018 Mar;12(3):391-405. doi: 10.1002/1878-0261.12173. Epub 2018 Feb 13.
• [1575] MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.Clin Cancer Res. 2020 Feb 1;26(3):746-757. doi: 10.1158/1078-0432.CCR-19-1611. Epub 2019 Oct 29.
• [1576] Effectiveness of Colorectal Cancer Screening in Detecting Earlier-Stage Disease-A Nationwide Cohort Study in Denmark.Gastroenterology. 2018 Jul;155(1):99-106. doi: 10.1053/j.gastro.2018.03.062. Epub 2018 Apr 5.
• [1577] Correction to: Metalloproteases meprin- (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer.BMC Cancer. 2018 Jan 11;18(1):70. doi: 10.1186/s12885-017-3767-6.
• [1578] RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing.Mol Ther. 2020 Feb 5;28(2):599-612. doi: 10.1016/j.ymthe.2019.11.016. Epub 2019 Nov 20.
• [1579] Effects of supplemental vitamin D and calcium on markers of proliferation, differentiation, and apoptosis in the normal colorectal mucosa of colorectal adenoma patients.PLoS One. 2018 Dec 17;13(12):e0208762. doi: 10.1371/journal.pone.0208762. eCollection 2018.
• [1580] CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer.Mol Cancer. 2019 May 7;18(1):91. doi: 10.1186/s12943-019-1019-x.
• [1581] Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer.Clin Epigenetics. 2019 Mar 7;11(1):41. doi: 10.1186/s13148-019-0628-y.
• [1582] Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population.PLoS One. 2018 Mar 16;13(3):e0193547. doi: 10.1371/journal.pone.0193547. eCollection 2018.
• [1583] NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation.Onco Targets Ther. 2018 May 15;11:2843-2852. doi: 10.2147/OTT.S156814. eCollection 2018.
• [1584] E4bp4 regulates carboxylesterase 2 enzymes through repression of the nuclear receptor Rev-erb in mice.Biochem Pharmacol. 2018 Jun;152:293-301. doi: 10.1016/j.bcp.2018.04.005. Epub 2018 Apr 11.
• [1585] Intratumoral Heterogeneity of Somatic Mutations for NRIP1, DOK1, ULK1, ULK2, DLGAP3, PARD3 and PRKCI in Colon Cancers.Pathol Oncol Res. 2018 Oct;24(4):827-832. doi: 10.1007/s12253-017-0297-0. Epub 2017 Aug 26.
• [1586] Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX.Inflamm Bowel Dis. 2018 Feb 15;24(3):593-600. doi: 10.1093/ibd/izx071.
• [1587] Aberrant hypermethylation of OGDHL gene promoter in sporadic colorectal cancer.Curr Probl Cancer. 2020 Feb;44(1):100471. doi: 10.1016/j.currproblcancer.2019.03.001. Epub 2019 Mar 16.
• [1588] Potential Applications of DNA, RNA and Protein Biomarkers in Diagnosis, Therapy and Prognosis for Colorectal Cancer: A Study from Databases to AI-Assisted Verification.Cancers (Basel). 2019 Feb 1;11(2):172. doi: 10.3390/cancers11020172.
• [1589] Transfection of PDCD5 sensitizes colorectal cancer cells to cisplatin-induced apoptosis in vitro and in vivo. Eur J Pharmacol. 2010 Dec 15;649(1-3):120-6. doi: 10.1016/j.ejphar.2010.09.040. Epub 2010 Sep 24.
• [1590] RPS24c Isoform Facilitates Tumor Angiogenesis Via Promoting the Stability of MVIH in Colorectal Cancer.Curr Mol Med. 2020;20(5):388-395. doi: 10.2174/1566524019666191203123943.
• [1591] PIAS3-mediated feedback loops promote chronic colitis-associated malignant transformation.Theranostics. 2018 Apr 30;8(11):3022-3037. doi: 10.7150/thno.23046. eCollection 2018.
• [1592] The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls.Expert Opin Biol Ther. 2020 Jan;20(1):15-22. doi: 10.1080/14712598.2020.1677603. Epub 2019 Oct 16.
• [1593] Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.Mol Cancer. 2018 Jan 30;17(1):16. doi: 10.1186/s12943-018-0767-3.
• [1594] Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2.J Biol Chem. 2005 Apr 8;280(14):14028-41. doi: 10.1074/jbc.M413766200. Epub 2005 Feb 4.
• [1595] High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma.Mol Cancer. 2015 Apr 28;14:95. doi: 10.1186/s12943-015-0356-7.
• [1596] Prokineticin 2 expression as a novel prognostic biomarker for human colorectal cancer.Oncotarget. 2018 Jul 10;9(53):30079-30091. doi: 10.18632/oncotarget.25706. eCollection 2018 Jul 10.
• [1597] PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2.Oncotarget. 2018 May 29;9(41):26342-26352. doi: 10.18632/oncotarget.25254. eCollection 2018 May 29.
• [1598] Two precision medicine predictive tools for six malignant solid tumors: from gene-based research to clinical application.J Transl Med. 2019 Dec 3;17(1):405. doi: 10.1186/s12967-019-02151-8.
• [1599] PTPN9 induces cell apoptosis by mitigating the activation of Stat3 and acts as a tumor suppressor in colorectal cancer.Cancer Manag Res. 2019 Feb 8;11:1309-1319. doi: 10.2147/CMAR.S187001. eCollection 2019.
• [1600] PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia.Mol Cell. 2020 Jan 2;77(1):95-107.e5. doi: 10.1016/j.molcel.2019.09.018. Epub 2019 Oct 15.
• [1601] Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling.Cancer Res. 2019 Aug 15;79(16):4099-4112. doi: 10.1158/0008-5472.CAN-18-4075. Epub 2019 Jun 25.
• [1602] MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer.Oncotarget. 2017 Dec 12;9(3):3830-3841. doi: 10.18632/oncotarget.23237. eCollection 2018 Jan 9.
• [1603] High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway.J Exp Clin Cancer Res. 2018 Jul 31;37(1):178. doi: 10.1186/s13046-018-0827-y.
• [1604] The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.Oncol Lett. 2018 May;15(5):7661-7668. doi: 10.3892/ol.2018.8305. Epub 2018 Mar 20.
• [1605] RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.JCI Insight. 2019 Jun 25;5(15):e127552. doi: 10.1172/jci.insight.127552.
• [1606] RBBP6, a RING finger-domain E3 ubiquitin ligase, induces epithelial-mesenchymal transition and promotes metastasis of colorectal cancer.Cell Death Dis. 2019 Nov 4;10(11):833. doi: 10.1038/s41419-019-2070-7.
• [1607] RCC2 is a novel p53 target in suppressing metastasis.Oncogene. 2018 Jan 4;37(1):8-17. doi: 10.1038/onc.2017.306. Epub 2017 Sep 4.
• [1608] Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal Cancer.Mol Cancer Res. 2020 Feb;18(2):264-277. doi: 10.1158/1541-7786.MCR-19-0748. Epub 2019 Nov 8.
• [1609] RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/-catenin signalling pathway.Exp Cell Res. 2018 Jul 1;368(1):24-36. doi: 10.1016/j.yexcr.2018.04.009. Epub 2018 Apr 11.
• [1610] Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating -catenin via a novel C-terminal domain.PLoS Biol. 2018 Jan 16;16(1):e2003714. doi: 10.1371/journal.pbio.2003714. eCollection 2018 Jan.
• [1611] CREPT facilitates colorectal cancer growth through inducing Wnt/-catenin pathway by enhancing p300-mediated -catenin acetylation.Oncogene. 2018 Jun;37(26):3485-3500. doi: 10.1038/s41388-018-0161-z. Epub 2018 Mar 22.
• [1612] Downregulation of RPS15A by miR-29a-3p attenuates cell proliferation in colorectal carcinoma.Biosci Biotechnol Biochem. 2019 Nov;83(11):2057-2064. doi: 10.1080/09168451.2019.1637712. Epub 2019 Jul 13.
• [1613] Overexpression of secretagogin promotes cell apoptosis and inhibits migration and invasion of human SW480 human colorectal cancer cells.Biomed Pharmacother. 2018 May;101:342-347. doi: 10.1016/j.biopha.2018.01.147. Epub 2018 Mar 22.
• [1614] Long noncoding RNA TMEM75 promotes colorectal cancer progression by activation of SIM2.Gene. 2018 Oct 30;675:80-87. doi: 10.1016/j.gene.2018.06.096. Epub 2018 Jun 30.
• [1615] SIX4 activates Akt and promotes tumor angiogenesis.Exp Cell Res. 2019 Oct 1;383(1):111495. doi: 10.1016/j.yexcr.2019.111495. Epub 2019 Jul 10.
• [1616] MALAT1 sponges miR-106b-5p to promote the invasion and metastasis of colorectal cancer via SLAIN2 enhanced microtubules mobility.EBioMedicine. 2019 Mar;41:286-298. doi: 10.1016/j.ebiom.2018.12.049. Epub 2019 Feb 21.
• [1617] Identification, isolation and characterization of human LGR5-positive colon adenoma cells.Development. 2018 Mar 14;145(6):dev153049. doi: 10.1242/dev.153049.
• [1618] SNX9 determines the surface levels of integrin 1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9.J Cell Physiol. 2019 Aug;234(10):17280-17294. doi: 10.1002/jcp.28346. Epub 2019 Feb 19.
• [1619] Decreased expression of SorCS1 in colorectal cancer: An independent predictor of poor prognosis.Neoplasma. 2020 Jan;67(1):119-128. doi: 10.4149/neo_2019_190221N146. Epub 2019 Dec 9.
• [1620] MicroRNA-181a promotes angiogenesis in colorectal cancer by targeting SRCIN1 to promote the SRC/VEGF signaling pathway.Cell Death Dis. 2018 Apr 1;9(4):438. doi: 10.1038/s41419-018-0490-4.
• [1621] Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer.Cancer Lett. 2019 Jul 10;454:53-65. doi: 10.1016/j.canlet.2019.04.014. Epub 2019 Apr 11.
• [1622] TEAD4 promotes colorectal tumorigenesis via transcriptionally targeting YAP1.Cell Cycle. 2018;17(1):102-109. doi: 10.1080/15384101.2017.1403687. Epub 2018 Jan 4.
• [1623] Overexpression of the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1 is associated with the poor prognosis of patients with colorectal cancer.Oncol Lett. 2018 Apr;15(4):5451-5458. doi: 10.3892/ol.2018.8042. Epub 2018 Feb 13.
• [1624] Expression of THSD7A in neoplasm tissues and its relationship with proteinuria.BMC Nephrol. 2019 Aug 23;20(1):332. doi: 10.1186/s12882-019-1489-5.
• [1625] Long noncoding MAGI2-AS3 promotes colorectal cancer progression through regulating miR-3163/TMEM106B axis.J Cell Physiol. 2020 May;235(5):4824-4833. doi: 10.1002/jcp.29360. Epub 2019 Nov 10.
• [1626] Silencing of TMEM158 Inhibits Tumorigenesis and Multidrug Resistance in Colorectal Cancer.Nutr Cancer. 2020;72(4):662-671. doi: 10.1080/01635581.2019.1650192. Epub 2019 Aug 7.
• [1627] Knockdown of TMEM45A overcomes multidrug resistance and epithelial-mesenchymal transition in human colorectal cancer cells through inhibition of TGF- signalling pathway.Clin Exp Pharmacol Physiol. 2020 Mar;47(3):503-516. doi: 10.1111/1440-1681.13220. Epub 2019 Dec 29.
• [1628] TIPE1 impairs stemness maintenance in colorectal cancer through directly targeting -catenin.Carcinogenesis. 2020 Mar 13;41(1):25-35. doi: 10.1093/carcin/bgz079.
• [1629] TNNT1, negatively regulated by miR-873, promotes the progression of colorectal cancer.J Gene Med. 2020 Feb;22(2):e3152. doi: 10.1002/jgm.3152. Epub 2019 Dec 23.
• [1630] VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers.Sci Immunol. 2019 Nov 8;4(41):eaay0555. doi: 10.1126/sciimmunol.aay0555.
• [1631] The family of apoptosis-stimulating proteins of p53 is dysregulated in colorectal cancer patients.Oncol Lett. 2018 May;15(5):6409-6417. doi: 10.3892/ol.2018.8151. Epub 2018 Mar 1.
• [1632] miR-181a-2* expression is different amongst carcinomas from the colorectal serrated route.Mutagenesis. 2020 Jul 11;35(3):233-241. doi: 10.1093/mutage/gez039.
• [1633] TRIM14 promotes cell proliferation and inhibits apoptosis by suppressing PTEN in colorectal cancer.Cancer Manag Res. 2019 Jun 24;11:5725-5735. doi: 10.2147/CMAR.S210782. eCollection 2019.
• [1634] TRIM31 regulates chronic inflammation via NF-B signal pathway to promote invasion and metastasis in colorectal cancer.Am J Transl Res. 2018 Apr 15;10(4):1247-1259. eCollection 2018.
• [1635] Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones.Histopathology. 2018 Feb;72(3):423-432. doi: 10.1111/his.13398. Epub 2017 Dec 4.
• [1636] AA-NAT, MT1 and MT2 Correlates with Cancer Stem-Like Cell Markers in Colorectal Cancer: Study of the Influence of Stage and p53 Status of Tumors.Int J Mol Sci. 2017 Jun 11;18(6):1251. doi: 10.3390/ijms18061251.
• [1637] Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer.Cancer Res. 2017 Aug 1;77(15):4078-4088. doi: 10.1158/0008-5472.CAN-17-0682. Epub 2017 Jun 13.
• [1638] Elevated microRNA-23a Expression Enhances the Chemoresistance of Colorectal Cancer Cells with Microsatellite Instability to 5-Fluorouracil by Directly Targeting ABCF1.Curr Protein Pept Sci. 2015;16(4):301-9. doi: 10.2174/138920371604150429153309.
• [1639] Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.Mol Cancer. 2014 Jun 9;13:145. doi: 10.1186/1476-4598-13-145.
• [1640] Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis.Clin Transl Immunology. 2017 Oct 6;6(10):e157. doi: 10.1038/cti.2017.42. eCollection 2017 Oct.
• [1641] Association study between CYP24A1 gene polymorphisms and cancer risk.Pathol Res Pract. 2020 Jan;216(1):152735. doi: 10.1016/j.prp.2019.152735. Epub 2019 Nov 11.
• [1642] Risk of Malignant Cancers in Inflammatory Bowel Disease.J Crohns Colitis. 2019 Sep 27;13(10):1302-1310. doi: 10.1093/ecco-jcc/jjz058.
• [1643] CCX-CKR expression in colorectal cancer and patient survival.Int J Biol Markers. 2014 Mar 24;29(1):e40-8. doi: 10.5301/jbm.5000057.
• [1644] SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p.Cancer Lett. 2017 Nov 28;409:104-115. doi: 10.1016/j.canlet.2017.09.001. Epub 2017 Sep 18.
• [1645] Genome-wide diet-gene interaction analyses for risk of colorectal cancer.PLoS Genet. 2014 Apr 17;10(4):e1004228. doi: 10.1371/journal.pgen.1004228. eCollection 2014 Apr.
• [1646] Cancer testis antigen OY-TES-1 expression and serum immunogenicity in colorectal cancer: its relationship to clinicopathological parameters.Int J Clin Exp Pathol. 2013 Nov 15;6(12):2835-45. eCollection 2013.
• [1647] A more physiological approach to lipid metabolism alterations in cancer: CRC-like organoids assessment.PLoS One. 2019 Jul 24;14(7):e0219944. doi: 10.1371/journal.pone.0219944. eCollection 2019.
• [1648] Acyl-CoA Synthetase 5 Promotes the Growth and Invasion of Colorectal Cancer Cells.Can J Gastroenterol Hepatol. 2017;2017:7615736. doi: 10.1155/2017/7615736. Epub 2017 Jul 20.
• [1649] Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma.Mod Pathol. 2017 Feb;30(2):267-277. doi: 10.1038/modpathol.2016.172. Epub 2016 Oct 7.
• [1650] Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.Cancer Biol Ther. 2019;20(7):967-978. doi: 10.1080/15384047.2019.1591122. Epub 2019 Mar 20.
• [1651] Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer.J Proteomics. 2017 Jan 30;152:33-40. doi: 10.1016/j.jprot.2016.10.011. Epub 2016 Oct 27.
• [1652] Upregulated expression of ACTL8 contributes to invasion and metastasis and indicates poor prognosis in colorectal cancer.Onco Targets Ther. 2019 Mar 1;12:1749-1763. doi: 10.2147/OTT.S185858. eCollection 2019.
• [1653] -Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation.PLoS One. 2015 Apr 10;10(4):e0120616. doi: 10.1371/journal.pone.0120616. eCollection 2015.
• [1654] Study of the expression and function of ACY1 in patients with colorectal cancer.Oncol Lett. 2017 Apr;13(4):2459-2464. doi: 10.3892/ol.2017.5702. Epub 2017 Feb 8.
• [1655] Role of microRNA-30c targeting ADAM19 in colorectal cancer.PLoS One. 2015 Mar 23;10(3):e0120698. doi: 10.1371/journal.pone.0120698. eCollection 2015.
• [1656] Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.Oncotarget. 2015 Feb 20;6(5):3420-31. doi: 10.18632/oncotarget.2852.
• [1657] Protective roles of matrix metalloproteinases: from mouse models to human cancer.Cell Cycle. 2009 Nov 15;8(22):3657-62. doi: 10.4161/cc.8.22.9956. Epub 2009 Dec 1.
• [1658] Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers.BMC Cancer. 2018 Aug 6;18(1):796. doi: 10.1186/s12885-018-4701-2.
• [1659] Adamts18 deficiency promotes colon carcinogenesis by enhancing -catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer.Oncotarget. 2017 Mar 21;8(12):18979-18990. doi: 10.18632/oncotarget.14866.
• [1660] The metalloprotease ADAMTS8 displays antitumor properties through antagonizing EGFR-MEK-ERK signaling and is silenced in carcinomas by CpG methylation.Mol Cancer Res. 2014 Feb;12(2):228-38. doi: 10.1158/1541-7786.MCR-13-0195. Epub 2013 Nov 1.
• [1661] ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling.Cell Physiol Biochem. 2017;44(4):1370-1380. doi: 10.1159/000485534. Epub 2017 Nov 30.
• [1662] ADAMTSL3/punctin-2, a gene frequently mutated in colorectal tumors, is widely expressed in normal and malignant epithelial cells, vascular endothelial cells and other cell types, and its mRNA is reduced in colon cancer.Int J Cancer. 2007 Oct 15;121(8):1710-6. doi: 10.1002/ijc.22882.
• [1663] Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer.Cancer Lett. 2019 Mar 1;444:127-135. doi: 10.1016/j.canlet.2018.12.009. Epub 2018 Dec 21.
• [1664] The Secretion of miR-200s by a PKC/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.Cell Rep. 2018 Apr 24;23(4):1178-1191. doi: 10.1016/j.celrep.2018.03.118.
• [1665] A phosphorylation-related variant ADD1-rs4963 modifies the risk of colorectal cancer.PLoS One. 2015 Mar 27;10(3):e0121485. doi: 10.1371/journal.pone.0121485. eCollection 2015.
• [1666] Discovery and Validation of Hypermethylated Markers for Colorectal Cancer.Dis Markers. 2016;2016:2192853. doi: 10.1155/2016/2192853. Epub 2016 Jul 14.
• [1667] Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/-Catenin Signaling Pathway.Med Sci Monit. 2018 Sep 19;24:6608-6616. doi: 10.12659/MSM.910105.
• [1668] The Interaction of CD97/ADGRE5 With -Catenin in Adherens Junctions Is Lost During Colorectal Carcinogenesis.Front Oncol. 2018 May 25;8:182. doi: 10.3389/fonc.2018.00182. eCollection 2018.
• [1669] GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism.Mol Cancer Res. 2019 Nov;17(11):2196-2207. doi: 10.1158/1541-7786.MCR-19-0436. Epub 2019 Aug 23.
• [1670] Associations of adiponectin receptor 2 (AdipoR2) gene polymorphisms and AdipoR2 protein expression levels with the risk of colorectal cancer: A case-control study.Mol Med Rep. 2017 Oct;16(4):3983-3993. doi: 10.3892/mmr.2017.7115. Epub 2017 Jul 31.
• [1671] ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.Clin Cancer Res. 2017 Jun 1;23(11):2769-2780. doi: 10.1158/1078-0432.CCR-16-1604. Epub 2016 Nov 30.
• [1672] MicroRNA 214 inhibits adipocyte enhancer-binding protein 1 activity and increases the sensitivity of chemotherapy in colorectal cancer.Oncol Lett. 2019 Jan;17(1):55-62. doi: 10.3892/ol.2018.9623. Epub 2018 Oct 26.
• [1673] AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers.Cancer Med. 2014 Aug;3(4):759-74. doi: 10.1002/cam4.237. Epub 2014 Apr 10.
• [1674] XB130 enhances invasion and migration of human colorectal cancer cells by promoting epithelialmesenchymal transition.Mol Med Rep. 2017 Oct;16(4):5592-5598. doi: 10.3892/mmr.2017.7279. Epub 2017 Aug 18.
• [1675] CRMP5-associated GTPase (CRAG) Is a Candidate Driver Gene for Colorectal Cancer Carcinogenesis.Anticancer Res. 2019 Jan;39(1):99-106. doi: 10.21873/anticanres.13084.
• [1676] Long interspersed nucleotide acid element-1 ORF-1 protein promotes proliferation and invasion of human colorectal cancer LoVo cells through enhancing ETS-1 activity.Genet Mol Res. 2014 Apr 14;13(3):6981-94. doi: 10.4238/2014.April.14.13.
• [1677] SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF.J Exp Clin Cancer Res. 2019 Apr 24;38(1):172. doi: 10.1186/s13046-019-1169-0.
• [1678] Kisspeptin effect on endothelial monocyte activating polypeptide II (EMAP-II)-associated lymphocyte cell death and metastases in colorectal cancer patients.Mol Med. 2014 Mar 18;20(1):80-92. doi: 10.2119/molmed.2013.00151.
• [1679] NFATC2 is a novel therapeutic target for colorectal cancer stem cells.Onco Targets Ther. 2018 Oct 15;11:6911-6924. doi: 10.2147/OTT.S169129. eCollection 2018.
• [1680] Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation.Nat Commun. 2017 May 18;8:15308. doi: 10.1038/ncomms15308.
• [1681] PKA RI/A-kinase anchoring proteins 10 signaling pathway and the prognosis of colorectal cancer.J Gastroenterol Hepatol. 2015 Mar;30(3):496-503. doi: 10.1111/jgh.12689.
• [1682] A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.J Exp Clin Cancer Res. 2015 Nov 21;34:142. doi: 10.1186/s13046-015-0258-y.
• [1683] FBI-1 enhances ETS-1 signaling activity and promotes proliferation of human colorectal carcinoma cells.PLoS One. 2014 May 23;9(5):e98041. doi: 10.1371/journal.pone.0098041. eCollection 2014.
• [1684] ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells.BMC Cancer. 2018 Aug 24;18(1):848. doi: 10.1186/s12885-018-4758-y.
• [1685] Dynamic bioenergetic alterations in colorectal adenomatous polyps and adenocarcinomas.EBioMedicine. 2019 Jun;44:334-345. doi: 10.1016/j.ebiom.2019.05.031. Epub 2019 May 20.
• [1686] Down-regulated and Commonly mutated ALPK1 in Lung and Colorectal Cancers.Sci Rep. 2016 Jun 10;6:27350. doi: 10.1038/srep27350.
• [1687] An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.Anticancer Res. 2017 Jul;37(7):3855-3862. doi: 10.21873/anticanres.11765.
• [1688] Development of a multiplex MethyLight assay for the detection of multigene methylation in human colorectal cancer.Cancer Genet Cytogenet. 2010 Oct 1;202(1):1-10. doi: 10.1016/j.cancergencyto.2010.05.018.
• [1689] CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.MAbs. 2014;6(6):1571-84. doi: 10.4161/19420862.2014.975660.
• [1690] Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer.Clin Cancer Res. 2015 Oct 15;21(20):4709-18. doi: 10.1158/1078-0432.CCR-15-0159. Epub 2015 Jun 12.
• [1691] Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1/GP78 axis.Oncogene. 2017 Nov 23;36(47):6555-6567. doi: 10.1038/onc.2017.263. Epub 2017 Jul 31.
• [1692] Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy.Int J Mol Sci. 2017 Apr 22;18(4):891. doi: 10.3390/ijms18040891.
• [1693] The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway.Cancer Lett. 2015 Apr 28;360(1):68-75. doi: 10.1016/j.canlet.2015.02.004. Epub 2015 Feb 7.
• [1694] Modulation of CDK2-AP1 (p12(DOC-1)) expression in human colorectal cancer.Oncogene. 2005 May 19;24(22):3657-68. doi: 10.1038/sj.onc.1208378.
• [1695] Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer.Sci Rep. 2018 May 9;8(1):7386. doi: 10.1038/s41598-018-25631-1.
• [1696] Serum Angiopoietin-like Protein 2 Improves Preoperative Detection of Lymph Node Metastasis in Colorectal Cancer.Anticancer Res. 2015 May;35(5):2849-56.
• [1697] ANKLE1 N(6) -Methyladenosine-related variant is associated with colorectal cancer risk by maintaining the genomic stability.Int J Cancer. 2020 Jun 15;146(12):3281-3293. doi: 10.1002/ijc.32677. Epub 2019 Nov 6.
• [1698] Clinical significance of Ankyrin repeat domain 12 expression in colorectal cancer.J Exp Clin Cancer Res. 2013 May 29;32(1):35. doi: 10.1186/1756-9966-32-35.
• [1699] The Expression of Melanoma-Associated Antigen D2 Both in Surgically Resected and Serum Samples Serves as Clinically Relevant Biomarker of Gastric Cancer Progression.Ann Surg Oncol. 2016 Feb;23 Suppl 2:S214-21. doi: 10.1245/s10434-015-4457-8. Epub 2015 Mar 6.
• [1700] Identification and characterization of ANO9 in stage II and III colorectal carcinoma.Oncotarget. 2015 Oct 6;6(30):29324-34. doi: 10.18632/oncotarget.4979.
• [1701] Study on molecular mechanism of ANOS1 promoting development of colorectal cancer.PLoS One. 2017 Aug 30;12(8):e0182964. doi: 10.1371/journal.pone.0182964. eCollection 2017.
• [1702] ANP32A modulates cell growth by regulating p38 and Akt activity in colorectal cancer.Oncol Rep. 2017 Sep;38(3):1605-1612. doi: 10.3892/or.2017.5845. Epub 2017 Jul 21.
• [1703] Tumor endothelial marker 8 promotes cancer progression and metastasis.Oncotarget. 2018 Jul 10;9(53):30173-30188. doi: 10.18632/oncotarget.25734. eCollection 2018 Jul 10.
• [1704] Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer.Oncotarget. 2017 Mar 28;8(13):21663-21673. doi: 10.18632/oncotarget.15523.
• [1705] The role of annexin A4 in cancer.Front Biosci (Landmark Ed). 2016 Jun 1;21(5):949-57. doi: 10.2741/4432.
• [1706] Annexin A9 promotes invasion and metastasis of colorectal cancer and predicts poor prognosis.Int J Mol Med. 2018 Apr;41(4):2185-2192. doi: 10.3892/ijmm.2018.3432. Epub 2018 Jan 29.
• [1707] Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).Hered Cancer Clin Pract. 2017 Nov 29;15:22. doi: 10.1186/s13053-017-0082-9. eCollection 2017.
• [1708] Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex.Oncotarget. 2017 Jul 11;8(28):45213-45223. doi: 10.18632/oncotarget.16779.
• [1709] Chromosome 20p11 gains are associated with liver-specific metastasis in patients with colorectal cancer.Gut. 2013 Jan;62(1):94-101. doi: 10.1136/gutjnl-2011-301587. Epub 2012 Jan 20.
• [1710] Apolipoprotein C1 (APOC1) promotes tumor progression via MAPK signaling pathways in colorectal cancer.Cancer Manag Res. 2019 May 29;11:4917-4930. doi: 10.2147/CMAR.S192529. eCollection 2019.
• [1711] Expression and potential role of apolipoprotein D on the death-survival balance of human colorectal cancer cells under oxidative stress conditions.Int J Colorectal Dis. 2013 Jun;28(6):751-66. doi: 10.1007/s00384-012-1616-2. Epub 2013 Jan 8.
• [1712] Apolipoprotein M increases the expression of vitamin D receptor mRNA in colorectal cancer cells detected with duplex fluorescence reverse transcription-quantitative polymerase chain reaction.Mol Med Rep. 2017 Aug;16(2):1167-1172. doi: 10.3892/mmr.2017.6716. Epub 2017 Jun 7.
• [1713] Experimental verification of a predicted novel microRNA located in human PIK3CA gene with a potential oncogenic function in colorectal cancer.Tumour Biol. 2016 Oct;37(10):14089-14101. doi: 10.1007/s13277-016-5264-y. Epub 2016 Aug 10.
• [1714] Overexpressed in colorectal carcinoma gene (OCC-1) upregulation and APPL2 gene downregulation in breast cancer specimens.Mol Biol Rep. 2018 Dec;45(6):1889-1895. doi: 10.1007/s11033-018-4336-z. Epub 2018 Sep 14.
• [1715] RNA interference-mediated silencing of aquaporin (AQP)-5 hinders angiogenesis of colorectal tumor by suppressing the production of vascular endothelial growth factor.Neoplasma. 2018;65(1):55-65. doi: 10.4149/neo_2018_161019N487.
• [1716] Comparison of the demographic characteristics of pediatric and adult colorectal cancer patients: a national inpatient sample based analysis.World J Pediatr. 2019 Feb;15(1):37-41. doi: 10.1007/s12519-018-0187-x. Epub 2018 Sep 27.
• [1717] AQP8 inhibits colorectal cancer growth and metastasis by down-regulating PI3K/AKT signaling and PCDH7 expression.Am J Cancer Res. 2018 Feb 1;8(2):266-279. eCollection 2018.
• [1718] Involvement of small ArfGAP1 (SMAP1), a novel Arf6-specific GTPase-activating protein, in microsatellite instability oncogenesis.Oncogene. 2014 May 22;33(21):2758-67. doi: 10.1038/onc.2013.211. Epub 2013 Jun 10.
• [1719] ARHGAP24 regulates cell ability and apoptosis of colorectal cancer cells via the regulation of P53.Oncol Lett. 2018 Sep;16(3):3517-3524. doi: 10.3892/ol.2018.9075. Epub 2018 Jul 4.
• [1720] ArhGAP30 promotes p53 acetylation and function in colorectal cancer.Nat Commun. 2014 Aug 26;5:4735. doi: 10.1038/ncomms5735.
• [1721] Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.Int J Clin Oncol. 2012 Apr;17(2):137-42. doi: 10.1007/s10147-011-0270-y. Epub 2011 Jun 24.
• [1722] Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer.Cancer Sci. 2015 Oct;106(10):1385-93. doi: 10.1111/cas.12768.
• [1723] GEFT protein expression in digestive tract malignant tumors and its clinical significance.Oncol Lett. 2019 Nov;18(5):5577-5590. doi: 10.3892/ol.2019.10915. Epub 2019 Sep 24.
• [1724] High expression of AT-rich interactive domain 3A (ARID3A) is associated with good prognosis in colorectal carcinoma.Ann Surg Oncol. 2014 Dec;21 Suppl 4:S481-9. doi: 10.1245/s10434-013-3435-2. Epub 2013 Dec 24.
• [1725] Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.Int J Cancer. 2014 Aug 1;135(3):611-23. doi: 10.1002/ijc.28705. Epub 2014 Jan 13.
• [1726] BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer.EBioMedicine. 2017 Jun;20:50-60. doi: 10.1016/j.ebiom.2017.05.001. Epub 2017 May 4.
• [1727] Antitumor Effects of Epidrug/IFN Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells.Cancer Immunol Res. 2017 Jul;5(7):604-616. doi: 10.1158/2326-6066.CIR-17-0080. Epub 2017 Jun 14.
• [1728] ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer.Eur J Hum Genet. 2008 Aug;16(8):983-91. doi: 10.1038/ejhg.2008.43. Epub 2008 Mar 12.
• [1729] Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth.Mol Cancer Ther. 2019 Mar;18(3):602-612. doi: 10.1158/1535-7163.MCT-18-0824. Epub 2019 Jan 15.
• [1730] microRNA-202-3p inhibits cell proliferation by targeting ADP-ribosylation factor-like 5A in human colorectal carcinoma.Clin Cancer Res. 2014 Mar 1;20(5):1146-57. doi: 10.1158/1078-0432.CCR-13-1023. Epub 2013 Dec 10.
• [1731] Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin 1/FAK axis.Oncotarget. 2015 May 10;6(13):11530-46. doi: 10.18632/oncotarget.3448.
• [1732] Short interfering RNA-mediated silencing of actin-related protein 2/3 complex subunit 4 inhibits the migration of SW620 human colorectal cancer cells.Oncol Lett. 2018 Mar;15(3):2847-2854. doi: 10.3892/ol.2017.7642. Epub 2017 Dec 19.
• [1733] Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway.Int J Mol Med. 2016 Mar;37(3):734-42. doi: 10.3892/ijmm.2016.2473. Epub 2016 Jan 29.
• [1734] Acid ceramidase is a novel drug target for pediatric brain tumors.Oncotarget. 2017 Apr 11;8(15):24753-24761. doi: 10.18632/oncotarget.15800.
• [1735] ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.Oncogene. 2010 Apr 22;29(16):2393-403. doi: 10.1038/onc.2010.6. Epub 2010 Feb 15.
• [1736] The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells.Chin J Cancer. 2017 Jan 14;36(1):11. doi: 10.1186/s40880-017-0180-0.
• [1737] The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer.Cancer Immunol Res. 2018 Mar;6(3):358-369. doi: 10.1158/2326-6066.CIR-17-0518. Epub 2018 Jan 25.
• [1738] Protumor Steering of Cancer Inflammation by p50 NF-B Enhances Colorectal Cancer Progression.Cancer Immunol Res. 2018 May;6(5):578-593. doi: 10.1158/2326-6066.CIR-17-0036. Epub 2018 Mar 27.
• [1739] Comprehensive Genetic Search to Clarify the Molecular Mechanism of Drug Resistance Identifies ASCL2-LEF1/TSPAN8 Axis in Colorectal Cancer.Ann Surg Oncol. 2019 May;26(5):1401-1411. doi: 10.1245/s10434-019-07172-7. Epub 2019 Jan 31.
• [1740] Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of -Catenin Target Genes.EBioMedicine. 2017 Jul;21:104-116. doi: 10.1016/j.ebiom.2017.06.007. Epub 2017 Jun 8.
• [1741] Silencing of argininosuccinate lyase inhibits colorectal cancer formation.Oncol Rep. 2017 Jan;37(1):163-170. doi: 10.3892/or.2016.5221. Epub 2016 Nov 7.
• [1742] Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments.Mol Oncol. 2019 Nov;13(11):2460-2475. doi: 10.1002/1878-0261.12577. Epub 2019 Oct 6.
• [1743] The activating transcription factor 2: an influencer of cancer progression.Mutagenesis. 2019 Dec 19;34(5-6):375-389. doi: 10.1093/mutage/gez041.
• [1744] Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia.J Gastroenterol. 2018 May;53(5):631-641. doi: 10.1007/s00535-017-1387-1. Epub 2017 Sep 7.
• [1745] Expression of activating transcription factor 7 is correlated with prognosis of colorectal cancer.J Cancer Res Ther. 2015 Apr-Jun;11(2):319-23. doi: 10.4103/0973-1482.148688.
• [1746] SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC.Autophagy. 2020 Apr;16(4):735-749. doi: 10.1080/15548627.2019.1632122. Epub 2019 Jul 4.
• [1747] The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.Gut. 2016 Mar;65(3):456-64. doi: 10.1136/gutjnl-2014-308735. Epub 2015 Feb 2.
• [1748] Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo.Autophagy. 2019 Feb;15(2):295-311. doi: 10.1080/15548627.2018.1517073. Epub 2018 Sep 20.
• [1749] miR-20a inhibits hypoxia-induced autophagy by targeting ATG5/FIP200 in colorectal cancer.Mol Carcinog. 2019 Jul;58(7):1234-1247. doi: 10.1002/mc.23006. Epub 2019 Mar 18.
• [1750] Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model.PLoS One. 2019 Feb 14;14(2):e0211916. doi: 10.1371/journal.pone.0211916. eCollection 2019.
• [1751] High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression.Oncol Rep. 2017 May;37(5):2955-2963. doi: 10.3892/or.2017.5554. Epub 2017 Apr 5.
• [1752] Investigation of the association between ATP2B4 and ATP5B genes with colorectal cancer.Gene. 2014 May 1;540(2):178-82. doi: 10.1016/j.gene.2014.02.050. Epub 2014 Feb 26.
• [1753] Novel genes associated with colorectal cancer are revealed by high resolution cytogenetic analysis in a patient specific manner.PLoS One. 2013 Oct 30;8(10):e76251. doi: 10.1371/journal.pone.0076251. eCollection 2013.
• [1754] Integrated exon level expression analysis of driver genes explain their role in colorectal cancer.PLoS One. 2014 Oct 21;9(10):e110134. doi: 10.1371/journal.pone.0110134. eCollection 2014.
• [1755] Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.Genetics. 2013 Nov;195(3):757-67. doi: 10.1534/genetics.113.156836. Epub 2013 Sep 3.
• [1756] Rad51C-ATXN7 fusion gene expression in colorectal tumors.Mol Cancer. 2016 Jun 13;15(1):47. doi: 10.1186/s12943-016-0527-1.
• [1757] Clinical correlation of B7-H3 and B3GALT4 with the prognosis of colorectal cancer.World J Gastroenterol. 2018 Aug 21;24(31):3538-3546. doi: 10.3748/wjg.v24.i31.3538.
• [1758] Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.Oncogene. 2017 Nov 16;36(46):6391-6407. doi: 10.1038/onc.2017.241. Epub 2017 Jul 24.
• [1759] 1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells.Oncotarget. 2014 Jun 15;5(11):3673-84. doi: 10.18632/oncotarget.1981.
• [1760] Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.Sci Rep. 2016 Mar 23;6:23642. doi: 10.1038/srep23642.
• [1761] -1,4-Galactosyltransferase III suppresses 1 integrin-mediated invasive phenotypes and negatively correlates with metastasis in colorectal cancer.Carcinogenesis. 2014 Jun;35(6):1258-66. doi: 10.1093/carcin/bgu007. Epub 2014 Jan 8.
• [1762] Lactosylceramide synthase -1,4-GalT-V: A novel target for the diagnosis and therapy of human colorectal cancer.Biochem Biophys Res Commun. 2019 Jan 8;508(2):380-386. doi: 10.1016/j.bbrc.2018.11.149. Epub 2018 Nov 28.
• [1763] Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.PLoS One. 2018 Apr 26;13(4):e0196245. doi: 10.1371/journal.pone.0196245. eCollection 2018.
• [1764] Pro-apoptotic PUMA and anti-apoptotic phospho-BAD are highly expressed in colorectal carcinomas.Dig Dis Sci. 2007 Oct;52(10):2751-6. doi: 10.1007/s10620-007-9799-z. Epub 2007 Mar 28.
• [1765] SODD promotes glucose uptake of colorectal cancer cells via AKT pathway.Cell Biol Int. 2017 Oct 31. doi: 10.1002/cbin.10907. Online ahead of print.
• [1766] Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.Genes Chromosomes Cancer. 2010 Mar;49(3):270-81. doi: 10.1002/gcc.20738.
• [1767] ARID1A facilitates KRAS signaling-regulatedenhancer activity in an AP1-dependent manner in colorectal cancer cells.Clin Epigenetics. 2019 Jun 19;11(1):92. doi: 10.1186/s13148-019-0690-5.
• [1768] SMAR1 inhibits Wnt/-catenin signaling and prevents colorectal cancer progression.Oncotarget. 2018 Apr 20;9(30):21322-21336. doi: 10.18632/oncotarget.25093. eCollection 2018 Apr 20.
• [1769] Down-regulation of Barx2 predicts poor survival in colorectal cancer.Biochem Biophys Res Commun. 2016 Sep 9;478(1):67-73. doi: 10.1016/j.bbrc.2016.07.091. Epub 2016 Jul 22.
• [1770] Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer.Gut. 2016 Jul;65(7):1139-50. doi: 10.1136/gutjnl-2014-308227. Epub 2015 Apr 2.
• [1771] Calycosin suppresses TGF--induced epithelial-to-mesenchymal transition and migration by upregulating BATF2 to target PAI-1 via the Wnt and PI3K/Akt signaling pathways in colorectal cancer cells.J Exp Clin Cancer Res. 2019 Jun 7;38(1):240. doi: 10.1186/s13046-019-1243-7.
• [1772] BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.Clin Cancer Res. 2016 Oct 1;22(19):4923-4933. doi: 10.1158/1078-0432.CCR-15-2664. Epub 2016 May 3.
• [1773] Bcl-B expression in human epithelial and nonepithelial malignancies.Clin Cancer Res. 2008 May 15;14(10):3011-21. doi: 10.1158/1078-0432.CCR-07-1955.
• [1774] BCL-3 promotes a cancer stem cell phenotype by enhancing -catenin signalling in colorectal tumour cells.Dis Model Mech. 2019 Mar 4;12(3):dmm037697. doi: 10.1242/dmm.037697.
• [1775] BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway.Int J Mol Med. 2018 May;41(5):2660-2668. doi: 10.3892/ijmm.2018.3451. Epub 2018 Feb 1.
• [1776] Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.Nat Commun. 2019 Feb 13;10(1):724. doi: 10.1038/s41467-018-08164-z.
• [1777] Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans.Carcinogenesis. 2018 Dec 13;39(11):1331-1341. doi: 10.1093/carcin/bgy122.
• [1778] No evidence for PML-RARa bcr1 fusion gene in colorectal cancer.Mol Biol Rep. 2012 May;39(5):5387-91. doi: 10.1007/s11033-011-1337-6. Epub 2011 Dec 14.
• [1779] Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer.Oncotarget. 2017 Nov 1;8(69):113431-113443. doi: 10.18632/oncotarget.22266. eCollection 2017 Dec 26.
• [1780] GLTSCR1 Negatively Regulates BRD4-Dependent Transcription Elongation and Inhibits CRC Metastasis.Adv Sci (Weinh). 2019 Oct 16;6(23):1901114. doi: 10.1002/advs.201901114. eCollection 2019 Dec.
• [1781] miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer.Oncol Rep. 2017 Jan;37(1):571-578. doi: 10.3892/or.2016.5278. Epub 2016 Nov 28.
• [1782] MicroRNA 486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells.Onco Targets Ther. 2018 Dec 6;11:8791-8801. doi: 10.2147/OTT.S180354. eCollection 2018.
• [1783] Novel Colitis Immunotherapy Targets Bin1 and Improves Colon Cell Barrier Function.Dig Dis Sci. 2016 Feb;61(2):423-32. doi: 10.1007/s10620-015-3804-8. Epub 2015 Jul 21.
• [1784] Overexpression of BIRC6 Is a Predictor of Prognosis for Colorectal Cancer.PLoS One. 2015 May 1;10(5):e0125281. doi: 10.1371/journal.pone.0125281. eCollection 2015.
• [1785] Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer.J Gastroenterol. 2017 Mar;52(3):327-340. doi: 10.1007/s00535-016-1222-0. Epub 2016 May 11.
• [1786] Co-occurrence of Lynch syndrome and juvenile polyposis syndrome confirmed by multigene panel testing.Fam Cancer. 2018 Jan;17(1):87-90. doi: 10.1007/s10689-017-0012-z.
• [1787] MicroRNA-205 Mediates Proteinase-Activated Receptor 2 (PAR(2)) -Promoted Cancer Cell Migration.Cancer Invest. 2017 Oct 21;35(9):601-609. doi: 10.1080/07357907.2017.1378671. Epub 2017 Oct 9.
• [1788] Black Patients with Colorectal Cancer Have More Advanced Cancer Stage at Time of Diagnosis: A Community-Based Safety-Net Hospital Experience.J Community Health. 2017 Aug;42(4):724-729. doi: 10.1007/s10900-016-0309-0.
• [1789] Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway.Cell Biol Toxicol. 2018 Aug;34(4):263-277. doi: 10.1007/s10565-017-9417-6. Epub 2017 Oct 24.
• [1790] New Wnt/-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.Gut. 2016 Oct;65(10):1690-701. doi: 10.1136/gutjnl-2014-307900. Epub 2015 Jul 8.
• [1791] LOH12CR1 is a Novel Tumor Suppressor Inhibiting Tumor Growth Through Deregulation of G1/S Checkpoint in Human Colorectal Carcinoma.Curr Mol Med. 2018;18(1):25-35. doi: 10.2174/1566524018666180608084005.
• [1792] Increased expression of BPI fold-containing family A member 1 is associated with metastasis and poor prognosis in human colorectal carcinoma.Oncol Lett. 2017 Oct;14(4):4231-4236. doi: 10.3892/ol.2017.6662. Epub 2017 Jul 25.
• [1793] The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin.J Cancer Res Clin Oncol. 2015 Aug;141(8):1465-74. doi: 10.1007/s00432-015-1937-y. Epub 2015 Feb 26.
• [1794] Detection of Pathogenic Germline Variants Among Patients With Advanced Colorectal Cancer Undergoing Tumor Genomic Profiling for Precision Medicine.Dis Colon Rectum. 2019 Apr;62(4):429-437. doi: 10.1097/DCR.0000000000001322.
• [1795] C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer.Br J Cancer. 2010 Jan 19;102(2):325-31. doi: 10.1038/sj.bjc.6605500. Epub 2010 Jan 5.
• [1796] Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer.Gastroenterology. 2018 Jan;154(1):181-194.e20. doi: 10.1053/j.gastro.2017.09.005. Epub 2017 Sep 12.
• [1797] DBC1 regulates Wnt/-catenin-mediated expression of MACC1, a key regulator of cancer progression, in colon cancer.Cell Death Dis. 2018 Aug 6;9(8):831. doi: 10.1038/s41419-018-0899-9.
• [1798] Effect of BRMS1 on tumorigenicity and metastasis of human rectal cancer.Cell Biochem Biophys. 2014 Sep;70(1):505-9. doi: 10.1007/s12013-014-9948-x.
• [1799] Sleeping beauty genetic screen identifies miR-23b::BTBD7 gene interaction as crucial for colorectal cancer metastasis.EBioMedicine. 2019 Aug;46:79-93. doi: 10.1016/j.ebiom.2019.06.044. Epub 2019 Jul 11.
• [1800] Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.Oncotarget. 2017 Oct 9;8(58):98623-98634. doi: 10.18632/oncotarget.21697. eCollection 2017 Nov 17.
• [1801] Ligand-Independent Epidermal Growth Factor Receptor Overexpression Correlates with Poor Prognosis in Colorectal Cancer.Cancer Res Treat. 2018 Oct;50(4):1351-1361. doi: 10.4143/crt.2017.487. Epub 2018 Jan 17.
• [1802] Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved.Cell Death Dis. 2019 Jul 1;10(7):509. doi: 10.1038/s41419-019-1747-2.
• [1803] Zoledronate can induce colorectal cancer microenvironment expressing BTN3A1 to stimulate effector T cells with antitumor activity.Oncoimmunology. 2017 Jan 6;6(3):e1278099. doi: 10.1080/2162402X.2016.1278099. eCollection 2017.
• [1804] Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.Sci Rep. 2016 Jul 15;6:29869. doi: 10.1038/srep29869.
• [1805] Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.Genes Chromosomes Cancer. 2016 Nov;55(11):855-63. doi: 10.1002/gcc.22385. Epub 2016 Jul 7.
• [1806] C14orf28 downregulated by miR-519d contributes to oncogenicity and regulates apoptosis and EMT in colorectal cancer.Mol Cell Biochem. 2017 Oct;434(1-2):197-208. doi: 10.1007/s11010-017-3049-2. Epub 2017 Apr 28.
• [1807] T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition.Biomed Res Int. 2018 Jun 21;2018:9532389. doi: 10.1155/2018/9532389. eCollection 2018.
• [1808] Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.Int J Clin Exp Pathol. 2015 Mar 1;8(3):2590-602. eCollection 2015.
• [1809] Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration.Ann Surg Oncol. 2015 Dec;22(13):4335-43. doi: 10.1245/s10434-015-4505-4. Epub 2015 Mar 28.
• [1810] Carbonic anhydrase-related protein VIII promotes colon cancer cell growth.Mol Carcinog. 2007 Mar;46(3):208-14. doi: 10.1002/mc.20264.
• [1811] microRNA-451a regulates colorectal cancer proliferation in response to radiation.BMC Cancer. 2018 May 3;18(1):517. doi: 10.1186/s12885-018-4370-1.
• [1812] The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.Am J Pathol. 2007 Nov;171(5):1509-19. doi: 10.2353/ajpath.2007.070331.
• [1813] The effect of S100A6 on nuclear translocation of CacyBP/SIP in colon cancer cells.PLoS One. 2018 Mar 13;13(3):e0192208. doi: 10.1371/journal.pone.0192208. eCollection 2018.
• [1814] Long noncoding RNA LINC00052 inhibits colorectal cancer metastasis by sponging microRNA-574-5p to modulate CALCOCO1 expression.J Cell Biochem. 2019 Oct;120(10):17258-17272. doi: 10.1002/jcb.28988. Epub 2019 May 19.
• [1815] L-CAM expression in lymph node and liver metastases of colorectal carcinomas.J Pathol. 1994 Feb;172(2):177-81. doi: 10.1002/path.1711720204.
• [1816] Association among resistin, adenylate cyclase-associated protein 1 and high-density lipoprotein cholesterol in patients with colorectal cancer: a multi-marker approach, as a hallmark of innovative predictive, preventive, and personalized medicine.EPMA J. 2019 Jul 20;10(3):307-316. doi: 10.1007/s13167-019-00178-x. eCollection 2019 Sep.
• [1817] Function of the macrophage-capping protein in colorectal carcinoma.Oncol Lett. 2017 Nov;14(5):5549-5555. doi: 10.3892/ol.2017.6888. Epub 2017 Sep 6.
• [1818] Gene polymorphisms related to insulin resistance and gene-environment interaction in colorectal cancer risk.Ann Hum Biol. 2015;42(6):560-8. doi: 10.3109/03014460.2014.1002532. Epub 2015 Jul 23.
• [1819] MicroRNA-195 inhibits colorectal cancer cell proliferation, colony-formation and invasion through targeting CARMA3.Mol Med Rep. 2014 Jul;10(1):473-8. doi: 10.3892/mmr.2014.2178. Epub 2014 Apr 24.
• [1820] CARF, As An Oncogene, Promotes Colorectal Cancer Stemness By Activating ERBB Signaling Pathway.Onco Targets Ther. 2019 Nov 1;12:9041-9051. doi: 10.2147/OTT.S225733. eCollection 2019.
• [1821] The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.Nucleic Acids Res. 2013 Mar 1;41(5):3047-55. doi: 10.1093/nar/gks1476. Epub 2013 Jan 17.
• [1822] Mutational analysis of caspase-14 gene in common carcinomas.Pathology. 2007 Jun;39(3):330-3. doi: 10.1080/00313020701329815.
• [1823] Identifying factors associated with the direction and significance of microRNA tumor-normal expression differences in colorectal cancer.BMC Cancer. 2017 Oct 30;17(1):707. doi: 10.1186/s12885-017-3690-x.
• [1824] PTRF suppresses the progression of colorectal cancers.Oncotarget. 2017 Jul 25;8(30):48650-48659. doi: 10.18632/oncotarget.9424.
• [1825] Heterochromatin protein HP1 promotes colorectal cancer progression and is regulated by miR-30a.Cancer Res. 2015 Nov 1;75(21):4593-604. doi: 10.1158/0008-5472.CAN-14-3735. Epub 2015 Sep 2.
• [1826] CBX4 Suppresses Metastasis via Recruitment of HDAC3 to the Runx2 Promoter in Colorectal Carcinoma.Cancer Res. 2016 Dec 15;76(24):7277-7289. doi: 10.1158/0008-5472.CAN-16-2100. Epub 2016 Nov 18.
• [1827] shRNAinduced knockdown of the SPERT gene inhibits proliferation and promotes apoptosis of human colorectal cancer RKO cells.Oncol Rep. 2018 Aug;40(2):813-822. doi: 10.3892/or.2018.6455. Epub 2018 May 21.
• [1828] The clinical significance of CCBE1 expression in human colorectal cancer.Cancer Manag Res. 2018 Nov 30;10:6581-6590. doi: 10.2147/CMAR.S181770. eCollection 2018.
• [1829] The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells.Cell Physiol Biochem. 2018;51(6):2547-2563. doi: 10.1159/000495924. Epub 2018 Dec 11.
• [1830] Plasma circular RNA panel acts as a novel diagnostic biomarker for colorectal cancer.Clin Biochem. 2019 Dec;74:60-68. doi: 10.1016/j.clinbiochem.2019.10.012. Epub 2019 Oct 26.
• [1831] Stem cell gene Girdin: a potential early liver metastasis predictor of colorectal cancer.Mol Biol Rep. 2012 Sep;39(9):8717-22. doi: 10.1007/s11033-012-1731-8. Epub 2012 Jun 20.
• [1832] Participation of CCL1 in Snail-Positive Fibroblasts in Colorectal Cancer Contribute to 5-Fluorouracil/Paclitaxel Chemoresistance.Cancer Res Treat. 2018 Jul;50(3):894-907. doi: 10.4143/crt.2017.356. Epub 2017 Sep 18.
• [1833] CCL19 suppresses angiogenesis through promoting miR-206 and inhibiting Met/ERK/Elk-1/HIF-1/VEGF-A pathway in colorectal cancer.Cell Death Dis. 2018 Sep 24;9(10):974. doi: 10.1038/s41419-018-1010-2.
• [1834] CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis.Oncotarget. 2017 Jan 17;8(3):5135-5148. doi: 10.18632/oncotarget.14095.
• [1835] Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.Cytokine. 2018 Oct;110:435-441. doi: 10.1016/j.cyto.2018.05.015. Epub 2018 May 23.
• [1836] A network-based, integrative approach to identify genes with aberrant co-methylation in colorectal cancer.Mol Biosyst. 2014 Feb;10(2):180-90. doi: 10.1039/c3mb70270g.
• [1837] MicroRNA-1246 promotes growth and metastasis of colorectal cancer cells involving CCNG2 reduction.Mol Med Rep. 2016 Jan;13(1):273-80. doi: 10.3892/mmr.2015.4557. Epub 2015 Nov 12.
• [1838] Functioning of people with colorectal cancer during chemotherapy. Demographic and clinical determinants of quality of life of patients with colorectal cancer receiving chemotherapy. Pilot study.Eur J Cancer Care (Engl). 2017 May;26(3). doi: 10.1111/ecc.12616. Epub 2016 Dec 27.
• [1839] TAp73 inhibits cell invasion and migration by directly activating KAI1 expression in colorectal carcinoma.Cancer Lett. 2018 Feb 28;415:106-116. doi: 10.1016/j.canlet.2017.12.002. Epub 2017 Dec 6.
• [1840] CD93 gene polymorphism is associated with disseminated colorectal cancer.Int J Colorectal Dis. 2015 Jul;30(7):883-90. doi: 10.1007/s00384-015-2247-1. Epub 2015 May 26.
• [1841] CDC27 Induces Metastasis and Invasion in Colorectal Cancer via the Promotion of Epithelial-To-Mesenchymal Transition.J Cancer. 2017 Aug 21;8(13):2626-2635. doi: 10.7150/jca.19381. eCollection 2017.
• [1842] Genome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese.Oncotarget. 2015 Nov 24;6(37):40327-36. doi: 10.18632/oncotarget.5530.
• [1843] CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.Cell Physiol Biochem. 2017;41(6):2475-2488. doi: 10.1159/000475916. Epub 2017 May 4.
• [1844] CDCA2 promotes the proliferation of colorectal cancer cells by activating the AKT/CCND1 pathway in vitro and in vivo.BMC Cancer. 2019 Jun 13;19(1):576. doi: 10.1186/s12885-019-5793-z.
• [1845] CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of -catenin and E-cadherin.Oncogene. 2020 Jan;39(1):219-233. doi: 10.1038/s41388-019-0983-3. Epub 2019 Aug 30.
• [1846] Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer.Gut. 2015 Apr;64(4):636-45. doi: 10.1136/gutjnl-2013-306620. Epub 2014 Jun 20.
• [1847] Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT.Tumour Biol. 2016 Jul;37(7):9077-88. doi: 10.1007/s13277-015-4555-z. Epub 2016 Jan 14.
• [1848] Aberrant Methylation of T-cadherin Can Be a Diagnostic Biomarker for Colorectal Cancer.Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):277-284. doi: 10.21873/cgp.20038.
• [1849] Frameshift mutations of cadherin genes DCHS2, CDH10 and CDH24 genes in gastric and colorectal cancers with high microsatellite instability.Pathol Oncol Res. 2015 Jan;21(1):181-5. doi: 10.1007/s12253-014-9804-8. Epub 2014 Jun 5.
• [1850] Comparative detection of aberrantly methylated DNA in preoperative and postoperative stool from patients with colorectal cancers.Int J Biol Markers. 2015 Jan-Mar;30(1):e81-7. doi: 10.5301/jbm.5000099.
• [1851] Loss of expression of -protocadherin and protocadherin-24 in sporadic and hereditary nonpolyposis colorectal cancers.Hum Pathol. 2019 Feb;84:299-308. doi: 10.1016/j.humpath.2018.09.019. Epub 2018 Oct 5.
• [1852] Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2.Mol Cancer Ther. 2017 Oct;16(10):2292-2303. doi: 10.1158/1535-7163.MCT-16-0666. Epub 2017 Jun 29.
• [1853] High expression of PFTK1 in cancer cells predicts poor prognosis in colorectal cancer.Mol Med Rep. 2017 Jul;16(1):224-230. doi: 10.3892/mmr.2017.6560. Epub 2017 May 10.
• [1854] Long noncoding RNA BLACAT1 indicates a poor prognosis of colorectal cancer and affects cell proliferation by epigenetically silencing of p15.Cell Death Dis. 2017 Mar 9;8(3):e2665. doi: 10.1038/cddis.2017.83.
• [1855] Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients.Oncotarget. 2014 Jul 15;5(13):4671-82. doi: 10.18632/oncotarget.2069.
• [1856] Epigenetic Status of CDO1 Gene May Reflect Chemosensitivity in Colon Cancer with Postoperative Adjuvant Chemotherapy.Ann Surg Oncol. 2019 Feb;26(2):406-414. doi: 10.1245/s10434-018-6865-z. Epub 2018 Oct 11.
• [1857] A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma.Histopathology. 2017 Jul;71(1):34-41. doi: 10.1111/his.13194. Epub 2017 Apr 11.
• [1858] A Risk Signature With Inflammatory and T Immune Cells Infiltration in Colorectal Cancer Predicting Distant Metastases and Efficiency of Chemotherapy.Front Oncol. 2019 Aug 13;9:704. doi: 10.3389/fonc.2019.00704. eCollection 2019.
• [1859] Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.Cancer Lett. 2013 Aug 9;336(1):85-95. doi: 10.1016/j.canlet.2013.04.007. Epub 2013 Apr 16.
• [1860] Integrative analysis of significant RNA-binding proteins in colorectal cancer metastasis.J Cell Biochem. 2018 Dec;119(12):9730-9741. doi: 10.1002/jcb.27290. Epub 2018 Aug 21.
• [1861] Functional role of long non-coding RNA CASC19/miR-140-5p/CEMIP axis in colorectal cancer progression in vitro.World J Gastroenterol. 2019 Apr 14;25(14):1697-1714. doi: 10.3748/wjg.v25.i14.1697.
• [1862] Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy.Cancer Res. 2005 Jun 1;65(11):4683-9. doi: 10.1158/0008-5472.CAN-04-3613.
• [1863] CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer.J Cancer. 2017 Jul 15;8(12):2163-2172. doi: 10.7150/jca.19940. eCollection 2017.
• [1864] CENPI is overexpressed in colorectal cancer and regulates cell migration and invasion.Gene. 2018 Oct 20;674:80-86. doi: 10.1016/j.gene.2018.06.067. Epub 2018 Jun 21.
• [1865] The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.Oncogene. 2016 May 5;35(18):2398-406. doi: 10.1038/onc.2015.290. Epub 2015 Aug 24.
• [1866] Low expression of centrosomal protein 78 (CEP78) is associated with poor prognosis of colorectal cancer patients.Chin J Cancer. 2016 Jun 29;35(1):62. doi: 10.1186/s40880-016-0121-3.
• [1867] Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer.Oncol Rep. 2018 Dec;40(6):3489-3500. doi: 10.3892/or.2018.6712. Epub 2018 Sep 18.
• [1868] Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells.Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):418-429. doi: 10.1016/j.bbamcr.2018.10.003. Epub 2018 Oct 5.
• [1869] CHD1L promotes tumor progression and predicts survival in colorectal carcinoma.J Surg Res. 2013 Nov;185(1):84-91. doi: 10.1016/j.jss.2013.05.008. Epub 2013 May 25.
• [1870] CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.Cancer Cell. 2017 May 8;31(5):653-668.e7. doi: 10.1016/j.ccell.2017.04.005.
• [1871] Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.Gastroenterology. 2014 Feb;146(2):530-38.e5. doi: 10.1053/j.gastro.2013.10.060. Epub 2013 Nov 6.
• [1872] Decreased expression of chromodomain helicase DNA-binding protein 9 is a novel independent prognostic biomarker for colorectal cancer.Braz J Med Biol Res. 2018 Jul 23;51(9):e7588. doi: 10.1590/1414-431X20187588.
• [1873] Phase II study of nab-paclitaxel in refractory small bowel adenocarcinoma and CpG island methylator phenotype (CIMP)-high colorectal cancer.Ann Oncol. 2018 Jan 1;29(1):139-144. doi: 10.1093/annonc/mdx688.
• [1874] Neuroendocrine differentiation is predictive of poor survival in patients with stage II colorectal cancer.Oncol Lett. 2017 Apr;13(4):2230-2236. doi: 10.3892/ol.2017.5681. Epub 2017 Feb 7.
• [1875] Aberrant DNA Methylation: Implications in Racial Health Disparity.PLoS One. 2016 Apr 25;11(4):e0153125. doi: 10.1371/journal.pone.0153125. eCollection 2016.
• [1876] Protective effect of curcumin against irinotecaninduced intestinal mucosal injury via attenuation of NFB activation, oxidative stress and endoplasmic reticulum stress.Int J Oncol. 2019 Apr;54(4):1376-1386. doi: 10.3892/ijo.2019.4714. Epub 2019 Feb 11.
• [1877] CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFB and/or caspase-3/7 signaling pathway.Oncol Lett. 2018 Nov;16(5):6140-6146. doi: 10.3892/ol.2018.9385. Epub 2018 Sep 3.
• [1878] New insights into frequency and contents of fear of cancer progression/recurrence (FOP/FCR) in outpatients with colorectal carcinoma (CRC) receiving oral capecitabine: a pilot study at a comprehensive cancer center.Patient Prefer Adherence. 2017 Nov 14;11:1907-1914. doi: 10.2147/PPA.S142784. eCollection 2017.
• [1879] Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer.Int J Cancer. 2014 Dec 1;135(11):2528-36. doi: 10.1002/ijc.28672. Epub 2014 Jan 6.
• [1880] Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC).Oncotarget. 2016 Jul 5;7(27):42225-42240. doi: 10.18632/oncotarget.9944.
• [1881] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.Cancer Sci. 2014 Apr;105(4):389-95. doi: 10.1111/cas.12362. Epub 2014 Feb 24.
• [1882] FL118 inhibits viability and induces apoptosis of colorectal cancer cells via inactivating the CIP2A/PP2A axis.Life Sci. 2019 Dec 15;239:117074. doi: 10.1016/j.lfs.2019.117074. Epub 2019 Nov 18.
• [1883] Predicting lymph node metastasis in early colorectal cancer using the CITED1 expression.J Surg Res. 2013 Nov;185(1):136-42. doi: 10.1016/j.jss.2013.05.041. Epub 2013 Jun 2.
• [1884] CITED4 gene silencing in colorectal cancer cells modulates adherens/tight junction gene expression and reduces cell proliferation.J Cancer Res Clin Oncol. 2016 Jan;142(1):225-37. doi: 10.1007/s00432-015-2011-5. Epub 2015 Aug 5.
• [1885] CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells.Mol Med Rep. 2013 Dec;8(6):1630-4. doi: 10.3892/mmr.2013.1716. Epub 2013 Oct 8.
• [1886] Terminal deoxynucleotidyl transferase-initiated molecule beacons arrayed aptamer probe for sensitive detection of metastatic colorectal cancer cells.Talanta. 2019 Sep 1;202:152-158. doi: 10.1016/j.talanta.2019.04.065. Epub 2019 Apr 28.
• [1887] Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer.Oncotarget. 2016 Jun 14;7(24):36632-36644. doi: 10.18632/oncotarget.9126.
• [1888] MiR-519b-3p Inhibits the Proliferation and Invasion in Colorectal Cancer via Modulating the uMtCK/Wnt Signaling Pathway.Front Pharmacol. 2019 Jul 2;10:741. doi: 10.3389/fphar.2019.00741. eCollection 2019.
• [1889] The prognostic role of Skp2 and the tumor suppressor protein p27 in colorectal cancer.J BUON. 2017 Sep-Oct;22(5):1122-1130.
• [1890] Expression of the Ca2+-activated chloride channel genes CLCA1 and CLCA2 is downregulated in human colorectal cancer.DNA Cell Biol. 2001 Jun;20(6):331-8. doi: 10.1089/10445490152122442.
• [1891] Regulation of the expression of claudin 23 by the enhancer of zeste 2 polycomb group protein in colorectal cancer.Mol Med Rep. 2015 Jul;12(1):728-36. doi: 10.3892/mmr.2015.3378. Epub 2015 Feb 19.
• [1892] Claudin-7 gene knockout causes destruction of intestinal structure and animal death in mice.World J Gastroenterol. 2019 Feb 7;25(5):584-599. doi: 10.3748/wjg.v25.i5.584.
• [1893] CLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling.Cancer Manag Res. 2019 Apr 30;11:3741-3751. doi: 10.2147/CMAR.S189558. eCollection 2019.
• [1894] Identification and meta-analysis of copy number variation-driven circadian clock genes for colorectal cancer.Oncol Lett. 2019 Nov;18(5):4816-4824. doi: 10.3892/ol.2019.10830. Epub 2019 Sep 9.
• [1895] CMTM4 inhibits cell proliferation and migration via AKT, ERK1/2, and STAT3 pathway in colorectal cancer.Acta Biochim Biophys Sin (Shanghai). 2019 Sep 6;51(9):915-924. doi: 10.1093/abbs/gmz084.
• [1896] Expression of chicken ovalbumin upstream promoter-transcription factor II and liver X receptor as prognostic indicators for human colorectal cancer.Oncol Lett. 2017 Oct;14(4):4011-4020. doi: 10.3892/ol.2017.6659. Epub 2017 Jul 24.
• [1897] Establishment and Characterization of Paired Primary and Peritoneal Seeding Human Colorectal Cancer Cell Lines: Identification of Genes That Mediate Metastatic Potential.Transl Oncol. 2018 Oct;11(5):1232-1243. doi: 10.1016/j.tranon.2018.07.014. Epub 2018 Aug 14.
• [1898] Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.Cancer Res. 2017 Feb 1;77(3):766-779. doi: 10.1158/0008-5472.CAN-16-1346. Epub 2016 Nov 29.
• [1899] Serum CNPY2 isoform 2 represents a novel biomarker for early detection of colorectal cancer.Aging (Albany NY). 2018 Aug 2;10(8):1921-1931. doi: 10.18632/aging.101512.
• [1900] Screening of exon methylation biomarkers for colorectal cancer via LC-MS/MS strategy.J Mass Spectrom. 2017 Dec;52(12):860-866. doi: 10.1002/jms.4032.
• [1901] TMED6-COG8 is a novel molecular marker of TFE3 translocation renal cell carcinoma.Int J Clin Exp Pathol. 2015 Mar 1;8(3):2690-9. eCollection 2015.
• [1902] High expression of COL10A1 is associated with poor prognosis in colorectal cancer.Onco Targets Ther. 2018 Mar 20;11:1571-1581. doi: 10.2147/OTT.S160196. eCollection 2018.
• [1903] Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.Oncotarget. 2016 Feb 23;7(8):8823-38. doi: 10.18632/oncotarget.6815.
• [1904] FMNL2 destabilises COMMD10 to activate NF-B pathway in invasion and metastasis of colorectal cancer.Br J Cancer. 2017 Oct 10;117(8):1164-1175. doi: 10.1038/bjc.2017.260. Epub 2017 Aug 17.
• [1905] Coping With Prediagnosis Symptoms of Colorectal Cancer: A Study of 244 Individuals With Recent Diagnosis.Cancer Nurs. 2017 Mar/Apr;40(2):145-151. doi: 10.1097/NCC.0000000000000361.
• [1906] Downregulation of cyclooxygenase? stimulates mitochondrial apoptosis through the NFB signaling pathway in colorectal cancer cells.Oncol Rep. 2019 Jan;41(1):559-569. doi: 10.3892/or.2018.6785. Epub 2018 Oct 12.
• [1907] High Expression of RAR Is a Favorable Factor in Colorectal Cancer.Dis Markers. 2019 Mar 3;2019:7138754. doi: 10.1155/2019/7138754. eCollection 2019.
• [1908] Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer.Oncotarget. 2017 Apr 18;8(16):26858-26870. doi: 10.18632/oncotarget.15844.
• [1909] High expression of cytoplasmic polyadenylation element-binding protein 4 correlates with poor prognosis of patients with colorectal cancer.Virchows Arch. 2017 Jan;470(1):37-45. doi: 10.1007/s00428-016-2037-3. Epub 2016 Oct 22.
• [1910] Circulating exosomal CPNE3 as a diagnostic and prognostic biomarker for colorectal cancer.J Cell Physiol. 2019 Feb;234(2):1416-1425. doi: 10.1002/jcp.26936. Epub 2018 Aug 5.
• [1911] CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis.Oncogene. 2018 Nov;37(46):6025-6040. doi: 10.1038/s41388-018-0384-z. Epub 2018 Jul 11.
• [1912] Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via -catenin.Nat Cell Biol. 2018 Nov;20(11):1303-1314. doi: 10.1038/s41556-018-0215-z. Epub 2018 Oct 22.
• [1913] LncRNA SNHG5 affects cell proliferation, metastasis and migration of colorectal cancer through regulating miR-132-3p/CREB5.Cancer Biol Ther. 2019;20(4):524-536. doi: 10.1080/15384047.2018.1537579. Epub 2018 Nov 5.
• [1914] 15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1.Cell Signal. 2017 Nov;39:44-54. doi: 10.1016/j.cellsig.2017.07.022. Epub 2017 Jul 28.
• [1915] Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.Int J Biochem Cell Biol. 2014 Feb;47:68-75. doi: 10.1016/j.biocel.2013.11.022. Epub 2013 Dec 11.
• [1916] Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population.J Zhejiang Univ Sci B. 2013 Jan;14(1):47-57. doi: 10.1631/jzus.B1200218.
• [1917] Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.Tumour Biol. 2014 May;35(5):4419-23. doi: 10.1007/s13277-013-1581-6. Epub 2014 Jan 10.
• [1918] Let?d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway.Int J Oncol. 2018 Aug;53(2):781-790. doi: 10.3892/ijo.2018.4419. Epub 2018 May 23.
• [1919] Antibody-sandwich ELISA analysis of a novel blood biomarker of CST4 in gastrointestinal cancers.Onco Targets Ther. 2018 Mar 28;11:1743-1756. doi: 10.2147/OTT.S149204. eCollection 2018.
• [1920] Expression and epigenetic regulation of cystatin B in lung cancer and colorectal cancer.Pathol Res Pract. 2017 Dec;213(12):1568-1574. doi: 10.1016/j.prp.2017.06.007. Epub 2017 Jun 6.
• [1921] Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome.Genes Chromosomes Cancer. 2006 Apr;45(4):392-400. doi: 10.1002/gcc.20298.
• [1922] Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-B signaling.Cell Death Dis. 2019 Apr 3;10(4):304. doi: 10.1038/s41419-019-1537-x.
• [1923] Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases.J Biol Chem. 2006 Dec 8;281(49):37828-35. doi: 10.1074/jbc.M602119200. Epub 2006 Oct 6.
• [1924] Identification and validation of colorectal neoplasia-specific methylation biomarkers based on CTCF-binding sites.Oncotarget. 2017 Dec 11;8(69):114183-114194. doi: 10.18632/oncotarget.23172. eCollection 2017 Dec 26.
• [1925] Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression.Oncotarget. 2016 Aug 23;7(34):55518-55528. doi: 10.18632/oncotarget.10833.
• [1926] Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations.J Natl Cancer Inst. 2013 Dec 18;105(24):1852-61. doi: 10.1093/jnci/djt331. Epub 2013 Dec 7.
• [1927] MicroRNA-143-3p suppresses tumorigenesis by targeting catenin-1 in colorectal cancer.Onco Targets Ther. 2019 May 1;12:3255-3265. doi: 10.2147/OTT.S184118. eCollection 2019.
• [1928] Overexpression of -catenin is associated with a malignant phenotype and poor prognosis in colorectal cancer.Mol Med Rep. 2015 Sep;12(3):4259-4265. doi: 10.3892/mmr.2015.3918. Epub 2015 Jun 11.
• [1929] Characterization of cathepsin X in colorectal cancer development and progression.Pathol Res Pract. 2014 Dec;210(12):822-9. doi: 10.1016/j.prp.2014.08.014. Epub 2014 Sep 18.
• [1930] Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway.Oncotarget. 2017 Jan 3;8(1):1541-1554. doi: 10.18632/oncotarget.13652.
• [1931] Expression of CUEDC2 in colorectal cancer with different invasion and migration abilities.J Int Med Res. 2019 Feb;47(2):905-914. doi: 10.1177/0300060518813072. Epub 2019 Jan 17.
• [1932] Knockdown of CUL4B inhibits proliferation and promotes apoptosis of colorectal cancer cells through suppressing the Wnt/-catenin signaling pathway.Int J Clin Exp Pathol. 2015 Sep 1;8(9):10394-402. eCollection 2015.
• [1933] Expression and effect of CXCL14 in colorectal carcinoma.Mol Med Rep. 2014 Sep;10(3):1561-8. doi: 10.3892/mmr.2014.2343. Epub 2014 Jun 17.
• [1934] Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. Carcinogenesis. 2009 Jun;30(6):1041-8. doi: 10.1093/carcin/bgp073. Epub 2009 Mar 27.
• [1935] CYB5R1 links epithelial-mesenchymal transition and poor prognosis in colorectal cancer.Oncotarget. 2016 May 24;7(21):31350-60. doi: 10.18632/oncotarget.8912.
• [1936] ZFR promotes cell proliferation and tumor development in colorectal and liver cancers.Biochem Biophys Res Commun. 2019 Jun 11;513(4):1027-1034. doi: 10.1016/j.bbrc.2019.04.103. Epub 2019 Apr 19.
• [1937] Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO.Cancer Discov. 2015 Feb;5(2):198-211. doi: 10.1158/2159-8290.CD-14-0595. Epub 2014 Nov 28.
• [1938] DAB2IP with tumor-inhibiting activities exhibits frameshift mutations in gastrointestinal cancers.Pathol Res Pract. 2018 Dec;214(12):2075-2080. doi: 10.1016/j.prp.2018.10.005. Epub 2018 Oct 19.
• [1939] miR-182 contributes to cell proliferation, invasion and tumor growth in colorectal cancer by targeting DAB2IP.Int J Biochem Cell Biol. 2019 Jun;111:27-36. doi: 10.1016/j.biocel.2019.04.002. Epub 2019 Apr 8.
• [1940] MicroRNA-552 promotes tumor cell proliferation and migration by directly targeting DACH1 via the Wnt/-catenin signaling pathway in colorectal cancer.Oncol Lett. 2017 Sep;14(3):3795-3802. doi: 10.3892/ol.2017.6600. Epub 2017 Jul 18.
• [1941] DACT2 Epigenetic Stimulator Exerts Dual Efficacy for Colorectal Cancer Prevention and Treatment.Pharmacol Res. 2018 Mar;129:318-328. doi: 10.1016/j.phrs.2017.11.032. Epub 2017 Dec 1.
• [1942] DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019.
• [1943] Elevated serum DAND5 is associated with metastasis and predicts poor prognosis in colorectal cancer.United European Gastroenterol J. 2017 Aug;5(5):725-734. doi: 10.1177/2050640616674838. Epub 2016 Oct 12.
• [1944] Death associated protein 1 is correlated with the clinical outcome of patients with colorectal cancer and has a role in the regulation of cell death.Oncol Rep. 2014 Jan;31(1):175-82. doi: 10.3892/or.2013.2866. Epub 2013 Nov 20.
• [1945] Reduced DAXX Expression Is Associated with Reduced CD24 Expression in Colorectal Cancer.Cells. 2019 Oct 12;8(10):1242. doi: 10.3390/cells8101242.
• [1946] Genome-wide association study of colorectal cancer identifies six new susceptibility loci.Nat Commun. 2015 Jul 7;6:7138. doi: 10.1038/ncomms8138.
• [1947] Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer.Carcinogenesis. 2018 May 28;39(6):788-797. doi: 10.1093/carcin/bgy056.
• [1948] MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting Defective in Cullin Neddylation 1 Domain Containing 1 (DCUN1D1).Oncol Res. 2018 May 7;26(4):593-604. doi: 10.3727/096504017X14920318811712. Epub 2017 May 4.
• [1949] The phospholipase DDHD1 as a new target in colorectal cancer therapy.J Exp Clin Cancer Res. 2018 Apr 13;37(1):82. doi: 10.1186/s13046-018-0753-z.
• [1950] Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.Carcinogenesis. 2014 Dec;35(12):2787-97. doi: 10.1093/carcin/bgu205. Epub 2014 Sep 30.
• [1951] DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene.Cancer Sci. 2018 Aug;109(8):2479-2489. doi: 10.1111/cas.13661. Epub 2018 Jul 17.
• [1952] Long noncoding RNA DDX11-AS1 induced by YY1 accelerates colorectal cancer progression through targeting miR-873/CLDN7 axis.Eur Rev Med Pharmacol Sci. 2019 Jul;23(13):5714-5729. doi: 10.26355/eurrev_201907_18309.
• [1953] Functional consequence of the p53 codon 72 polymorphism in colorectal cancer.Oncotarget. 2017 Aug 29;8(44):76574-76586. doi: 10.18632/oncotarget.20580. eCollection 2017 Sep 29.
• [1954] Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3.Cell Death Dis. 2019 Aug 7;10(8):593. doi: 10.1038/s41419-019-1825-5.
• [1955] Lentiviral DDX46 knockdown inhibits growth and induces apoptosis in human colorectal cancer cells.Gene. 2015 Apr 15;560(2):237-44. doi: 10.1016/j.gene.2015.02.020. Epub 2015 Feb 11.
• [1956] Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas.Clin Cancer Res. 2001 Nov;7(11):3495-503.
• [1957] Defensin alpha 6 (DEFA6) is a prognostic marker in colorectal cancer.Cancer Biomark. 2019;24(4):485-495. doi: 10.3233/CBM-182221.
• [1958] Expression of the human antimicrobial peptide -defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells.Sci Rep. 2018 Dec 21;8(1):18043. doi: 10.1038/s41598-018-36387-z.
• [1959] The key genes underlying pathophysiology association between the type 2-diabetic and colorectal cancer.J Cell Physiol. 2018 Nov;233(11):8551-8557. doi: 10.1002/jcp.26440. Epub 2018 Jun 15.
• [1960] The clinical implication of cancer-associated microvasculature and fibroblast in advanced colorectal cancer patients with synchronous or metachronous metastases.PLoS One. 2014 Mar 18;9(3):e91811. doi: 10.1371/journal.pone.0091811. eCollection 2014.
• [1961] Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.Mol Carcinog. 2017 Jul;56(7):1743-1752. doi: 10.1002/mc.22631. Epub 2017 Mar 6.
• [1962] Dehydrogenase/reductase SDR family member2 silencing sensitizes an oxaliplatinresistant cell line to oxaliplatin by inhibiting excision repair crosscomplementing group 1 protein expression.Oncol Rep. 2019 Nov;42(5):1725-1734. doi: 10.3892/or.2019.7291. Epub 2019 Aug 22.
• [1963] DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting -catenin Signaling to Induce Expression of VEGFA.EBioMedicine. 2017 Apr;18:62-72. doi: 10.1016/j.ebiom.2017.03.012. Epub 2017 Mar 9.
• [1964] Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Cell Mol Life Sci. 2017 Jul;74(13):2395-2411. doi: 10.1007/s00018-017-2477-1. Epub 2017 Feb 21.
• [1965] Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc(716) mutant mice.Cancer Sci. 2019 Aug;110(8):2520-2528. doi: 10.1111/cas.14100. Epub 2019 Jul 7.
• [1966] Gene-dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression.Genes Chromosomes Cancer. 2014 Apr;53(4):339-48. doi: 10.1002/gcc.22144. Epub 2014 Jan 29.
• [1967] Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2.Onco Targets Ther. 2017 May 2;10:2367-2376. doi: 10.2147/OTT.S132708. eCollection 2017.
• [1968] Genetic variants in the WNT signaling pathway are protectively associated with colorectal cancer in a Saudi population.Saudi J Biol Sci. 2019 Feb;26(2):286-293. doi: 10.1016/j.sjbs.2018.05.018. Epub 2018 May 17.
• [1969] Oxidized unsaturated fatty acids induce apoptotic cell death in cultured cells.Mol Med Rep. 2019 Apr;19(4):2767-2773. doi: 10.3892/mmr.2019.9940. Epub 2019 Feb 5.
• [1970] IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer.Oncotarget. 2016 Jul 26;7(30):48456-48466. doi: 10.18632/oncotarget.10309.
• [1971] Dermokine as a novel biomarker for early-stage colorectal cancer.J Gastroenterol. 2010 Dec;45(12):1201-11. doi: 10.1007/s00535-010-0279-4. Epub 2010 Jul 21.
• [1972] Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation.J Exp Clin Cancer Res. 2018 Dec 4;37(1):299. doi: 10.1186/s13046-018-0958-1.
• [1973] Overexpression of DNAJB6 promotes colorectal cancer cell invasion through an IQGAP1/ERK-dependent signaling pathway.Mol Carcinog. 2015 Oct;54(10):1205-13. doi: 10.1002/mc.22194. Epub 2014 Jul 7.
• [1974] Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer.EBioMedicine. 2016 Jun;8:159-172. doi: 10.1016/j.ebiom.2016.05.003. Epub 2016 May 5.
• [1975] Impact of Genetic Variation in MicroRNA-binding Site on Susceptibility to Colorectal Cancer.Anticancer Res. 2016 Jul;36(7):3353-61.
• [1976] Diphthamide Biosynthesis 1 is a Novel Oncogene in Colorectal Cancer Cells and is Regulated by MiR-218-5p.Cell Physiol Biochem. 2017;44(2):505-514. doi: 10.1159/000485087. Epub 2017 Nov 17.
• [1977] Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer.Int J Surg. 2015 Jan;13:193-197. doi: 10.1016/j.ijsu.2014.11.036. Epub 2014 Dec 12.
• [1978] Developmental pluripotency-associated 4: a novel predictor for prognosis and a potential therapeutic target for colon cancer.J Exp Clin Cancer Res. 2015 Jun 11;34(1):60. doi: 10.1186/s13046-015-0176-z.
• [1979] miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma.Oncol Lett. 2017 Oct;14(4):4379-4383. doi: 10.3892/ol.2017.6674. Epub 2017 Jul 26.
• [1980] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.PLoS One. 2014 Jan 17;9(1):e85750. doi: 10.1371/journal.pone.0085750. eCollection 2014.
• [1981] Decreased expression of dual specificity phosphatase 22 in colorectal cancer and its potential prognostic relevance for stage IV CRC patients.Tumour Biol. 2015 Nov;36(11):8531-5. doi: 10.1007/s13277-015-3588-7. Epub 2015 Jun 2.
• [1982] Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas.Cancer Sci. 2018 Jan;109(1):250-258. doi: 10.1111/cas.13444. Epub 2017 Dec 8.
• [1983] Significant overexpression of DVL1 in Taiwanese colorectal cancer patients with liver metastasis.Int J Mol Sci. 2013 Oct 14;14(10):20492-507. doi: 10.3390/ijms141020492.
• [1984] Computational prediction and analysis of deleterious cancer associated missense mutations in DYNC1H1.Mol Cell Probes. 2017 Aug;34:21-29. doi: 10.1016/j.mcp.2017.04.004. Epub 2017 Apr 26.
• [1985] km23-1/DYNLRB1 regulation of MEK/ERK signaling and R-Ras in invasive human colorectal cancer cells.Cell Biol Int. 2020 Jan;44(1):155-165. doi: 10.1002/cbin.11215. Epub 2019 Aug 28.
• [1986] Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer.Cancer Manag Res. 2019 Jan 10;11:611-624. doi: 10.2147/CMAR.S182719. eCollection 2019.
• [1987] Upregulated miR-1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC.Cell Prolif. 2018 Dec;51(6):e12505. doi: 10.1111/cpr.12505. Epub 2018 Aug 24.
• [1988] Genome-wide analysis of aberrant DNA methylation for identification of potential biomarkers in colorectal cancer patients.Asian Pac J Cancer Prev. 2012;13(5):1917-21. doi: 10.7314/apjcp.2012.13.5.1917.
• [1989] Epigenetic silencing of endothelin-3 in colorectal cancer.Int J Immunopathol Pharmacol. 2016 Jun;29(2):333-40. doi: 10.1177/0394632015600371. Epub 2015 Dec 18.
• [1990] Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue.PLoS One. 2015 Jul 29;10(7):e0133987. doi: 10.1371/journal.pone.0133987. eCollection 2015.
• [1991] Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.Cell Death Dis. 2013 Oct 10;4(10):e851. doi: 10.1038/cddis.2013.379.
• [1992] FBLN3 inhibited the invasion and metastasis of colorectal cancer through the AKT/mTOR pathway.Neoplasma. 2019 May 23;66(3):336-342. doi: 10.4149/neo_2018_180703N441. Epub 2019 Feb 14.
• [1993] Aberrant promoter methylation of PPP1R3C and EFHD1 in plasma of colorectal cancer patients.Cancer Med. 2014 Oct;3(5):1235-45. doi: 10.1002/cam4.273. Epub 2014 May 24.
• [1994] DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.Cell Death Differ. 2016 Apr;23(4):707-22. doi: 10.1038/cdd.2015.133. Epub 2015 Oct 23.
• [1995] Down-regulation of EGFL8: a novel biomarker for advanced gastric cancer.Anticancer Res. 2011 Oct;31(10):3377-80.
• [1996] Effect of EI24 expression on the tumorigenesis of Apc(Min/+) colorectal cancer mouse model.Biochem Biophys Res Commun. 2019 Jul 5;514(4):1087-1092. doi: 10.1016/j.bbrc.2019.04.186. Epub 2019 May 13.
• [1997] Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.Oncotarget. 2017 Sep 5;8(60):101224-101243. doi: 10.18632/oncotarget.20642. eCollection 2017 Nov 24.
• [1998] The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling.Genomics Proteomics Bioinformatics. 2018 Feb;16(1):73-84. doi: 10.1016/j.gpb.2017.10.002. Epub 2018 Mar 2.
• [1999] Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells.Biosci Rep. 2014 Dec 12;34(6):e00161. doi: 10.1042/BSR20140078.
• [2000] Integrated Analysis of the Gene Expression Changes During Colorectal Cancer Progression by Bioinformatic Methods.J Comput Biol. 2019 Oct;26(10):1168-1176. doi: 10.1089/cmb.2019.0056. Epub 2019 Jun 26.
• [2001] miR-133a acts as a tumor suppressor in colorectal cancer by targeting eIF4A1. Tumour Biol. 2017 May;39(5):1010428317698389.
• [2002] Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer.J Exp Clin Cancer Res. 2019 May 14;38(1):196. doi: 10.1186/s13046-019-1178-z.
• [2003] eIF6 Promotes Colorectal Cancer Proliferation and Invasion by Regulating AKT-Related Signaling Pathways.J Biomed Nanotechnol. 2019 Jul 1;15(7):1556-1567. doi: 10.1166/jbn.2019.2792.
• [2004] Knockdown of ELMO3 Suppresses Growth, Invasion and Metastasis of Colorectal Cancer.Int J Mol Sci. 2016 Dec 16;17(12):2119. doi: 10.3390/ijms17122119.
• [2005] Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis.Carcinogenesis. 2016 Jan;37(1):87-95. doi: 10.1093/carcin/bgv161. Epub 2015 Nov 19.
• [2006] Empty Spiracles Homeobox 2 (EMX2) Inhibits the Invasion and Tumorigenesis in Colorectal Cancer Cells.Oncol Res. 2017 Apr 14;25(4):537-544. doi: 10.3727/096504016X14756640150695. Epub 2016 Oct 5.
• [2007] ENKUR Is Involved in the Regulation of Cellular Biology in Colorectal Cancer Cells via PI3K/Akt Signaling Pathway.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819841433. doi: 10.1177/1533033819841433.
• [2008] -enolase promotes tumorigenesis and metastasis via regulating AMPK/mTOR pathway in colorectal cancer.Mol Carcinog. 2017 May;56(5):1427-1437. doi: 10.1002/mc.22603. Epub 2017 Jan 12.
• [2009] A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS.Gut. 2015 Jan;64(1):111-20. doi: 10.1136/gutjnl-2013-306571. Epub 2014 Mar 19.
• [2010] The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family.Int J Oncol. 2013 Oct;43(4):1244-52. doi: 10.3892/ijo.2013.2052. Epub 2013 Aug 6.
• [2011] Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer.Cancers (Basel). 2018 Oct 22;10(10):393. doi: 10.3390/cancers10100393.
• [2012] Comparative integromics on the breast cancer-associated gene KIAA1632: clues to a cancer antigen domain.Int J Oncol. 2007 Jul;31(1):205-10.
• [2013] Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.Mol Cancer Res. 2013 Jul;11(7):689-98. doi: 10.1158/1541-7786.MCR-12-0673. Epub 2013 Apr 17.
• [2014] Elevated Expression of ERCC6 Confers Resistance to 5-Fluorouracil and Is Associated with Poor Patient Survival in Colorectal Cancer.DNA Cell Biol. 2017 Sep;36(9):781-786. doi: 10.1089/dna.2017.3768. Epub 2017 Jun 30.
• [2015] ERCC6L promotes cell growth and invasion in human colorectal cancer.Oncol Lett. 2019 Jul;18(1):237-246. doi: 10.3892/ol.2019.10297. Epub 2019 Apr 30.
• [2016] Expression of inositol-requiring enzyme 1 is downregulated in colorectal cancer.Oncol Lett. 2017 Mar;13(3):1109-1118. doi: 10.3892/ol.2017.5590. Epub 2017 Jan 11.
• [2017] Hypoxia-inducible ERO1 promotes cancer progression through modulation of integrin-1 modification and signalling in HCT116 colorectal cancer cells.Sci Rep. 2017 Aug 24;7(1):9389. doi: 10.1038/s41598-017-09976-7.
• [2018] ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer.Oncol Rep. 2019 Mar;41(3):1603-1615. doi: 10.3892/or.2018.6943. Epub 2018 Dec 19.
• [2019] ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer.Cancer Manag Res. 2018 Nov 22;10:6157-6166. doi: 10.2147/CMAR.S181265. eCollection 2018.
• [2020] Expression of endothelial cell-specific molecule-1 regulated by hypoxia inducible factor-1 in human colon carcinoma: impact of ESM-1 on prognosis and its correlation with clinicopathological features.Oncol Rep. 2012 Nov;28(5):1701-8. doi: 10.3892/or.2012.2012. Epub 2012 Sep 3.
• [2021] Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer.Oncotarget. 2016 Nov 8;7(45):73800-73816. doi: 10.18632/oncotarget.12070.
• [2022] ETHE1 overexpression promotes SIRT1 and PGC1 mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer.Oncotarget. 2019 Jun 18;10(40):4004-4017. doi: 10.18632/oncotarget.26958. eCollection 2019 Jun 18.
• [2023] ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet-derived growth factor BB.Int J Cancer. 2019 Jul 1;145(1):179-191. doi: 10.1002/ijc.32071. Epub 2019 Jan 28.
• [2024] Common genetic variation in ETV6 is associated with colorectal cancer susceptibility.Nat Commun. 2016 May 5;7:11478. doi: 10.1038/ncomms11478.
• [2025] MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles.Epigenetics. 2015;10(9):803-9. doi: 10.1080/15592294.2015.1068490. Epub 2015 Jul 17.
• [2026] EXOSC4 functions as a potential oncogene in development and progression of colorectal cancer.Mol Carcinog. 2018 Dec;57(12):1780-1791. doi: 10.1002/mc.22896. Epub 2018 Sep 21.
• [2027] EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways.Front Oncol. 2019 Jul 18;9:643. doi: 10.3389/fonc.2019.00643. eCollection 2019.
• [2028] EYA1 promotes tumor angiogenesis by activating the PI3K pathway in colorectal cancer.Exp Cell Res. 2018 Jun 1;367(1):37-46. doi: 10.1016/j.yexcr.2018.02.028. Epub 2018 Feb 27.
• [2029] EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer.Mol Carcinog. 2015 Dec;54(12):1748-57. doi: 10.1002/mc.22247. Epub 2015 Jan 25.
• [2030] High expression of FABP4 and FABP6 in patients with colorectal cancer.World J Surg Oncol. 2019 Oct 24;17(1):171. doi: 10.1186/s12957-019-1714-5.
• [2031] MiR-483-3p regulates oxaliplatin resistance by targeting FAM171B in human colorectal cancer cells.Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):725-736. doi: 10.1080/21691401.2019.1569530.
• [2032] A novel mechanism of keratin cytoskeleton organization through casein kinase I and FAM83H in colorectal cancer.J Cell Sci. 2013 Oct 15;126(Pt 20):4721-31. doi: 10.1242/jcs.129684. Epub 2013 Jul 31.
• [2033] Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.Gastroenterology. 2017 Jan;152(1):75-77.e4. doi: 10.1053/j.gastro.2016.09.041. Epub 2016 Oct 3.
• [2034] ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas.EMBO J. 2019 Jul 15;38(14):e99299. doi: 10.15252/embj.201899299. Epub 2019 Jun 18.
• [2035] The fecal hemoglobin concentration, age and sex test score: Development and external validation of a simple prediction tool for colorectal cancer detection in symptomatic patients.Int J Cancer. 2017 May 15;140(10):2201-2211. doi: 10.1002/ijc.30639. Epub 2017 Mar 6.
• [2036] The effect of age on anastomotic leakage in colorectal cancer surgery: A population-based study.J Surg Oncol. 2018 Jul;118(1):113-120. doi: 10.1002/jso.25108. Epub 2018 Jun 7.
• [2037] Identification of novel methylated targets in colorectal cancer by microarray analysis and construction of co-expression network.Oncol Lett. 2017 Sep;14(3):2643-2648. doi: 10.3892/ol.2017.6506. Epub 2017 Jun 30.
• [2038] Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1.J Cell Biochem. 2019 Oct;120(10):17838-17846. doi: 10.1002/jcb.29051. Epub 2019 May 30.
• [2039] DNA methylation biomarker candidates for early detection of colon cancer.Tumour Biol. 2012 Apr;33(2):363-72. doi: 10.1007/s13277-011-0302-2. Epub 2012 Jan 12.
• [2040] The FOXC1/FBP1 signaling axis promotes colorectal cancer proliferation by enhancing the Warburg effect.Oncogene. 2019 Jan;38(4):483-496. doi: 10.1038/s41388-018-0469-8. Epub 2018 Aug 31.
• [2041] miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer.Cell Death Dis. 2017 Jul 27;8(7):e2958. doi: 10.1038/cddis.2017.300.
• [2042] Preliminary Study of the Role F-Box Protein 32 (FBXO32) in Colorectal Neoplasms Through the Transforming Growth Factor beta (TGF-)/Smad4 Signalling Pathway.Med Sci Monit. 2018 Feb 21;24:1080-1088. doi: 10.12659/msm.908030.
• [2043] m(6)A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1.Mol Cancer. 2019 Apr 13;18(1):87. doi: 10.1186/s12943-019-1014-2.
• [2044] Focal adhesion molecule Kindlin-1 mediates activation of TGF- signaling by interacting with TGF-RI, SARA and Smad3 in colorectal cancer cells.Oncotarget. 2016 Nov 15;7(46):76224-76237. doi: 10.18632/oncotarget.12779.
• [2045] Kindlin-2 inhibited the growth and migration of colorectal cancer cells.Tumour Biol. 2015 Jun;36(6):4107-14. doi: 10.1007/s13277-015-3044-8. Epub 2015 Jan 30.
• [2046] Fisher linear discriminant analysis for classification and prediction of genomic susceptibility to stomach and colorectal cancers based on six STR loci in a northern Chinese Han population.PeerJ. 2019 May 28;7:e7004. doi: 10.7717/peerj.7004. eCollection 2019.
• [2047] Co-expression Network Analysis Identified Key Proteins in Association With Hepatic Metastatic Colorectal Cancer.Proteomics Clin Appl. 2019 Nov;13(6):e1900017. doi: 10.1002/prca.201900017. Epub 2019 Aug 23.
• [2048] Significance of FGF9 gene in resistance to anti-EGFR therapies targeting colorectal cancer: A subset of colorectal cancer patients with FGF9 upregulation may be resistant to anti-EGFR therapies.Mol Carcinog. 2017 Jan;56(1):106-117. doi: 10.1002/mc.22476. Epub 2016 Feb 24.
• [2049] Acceleration of leukocytes' epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer.Oncotarget. 2017 Apr 4;8(14):23237-23245. doi: 10.18632/oncotarget.15573.
• [2050] FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3-related pathways.Oncogenesis. 2018 Oct 2;7(9):77. doi: 10.1038/s41389-018-0088-9.
• [2051] Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma.PLoS One. 2013 Jul 29;8(7):e69660. doi: 10.1371/journal.pone.0069660. Print 2013.
• [2052] FKBP3 mediates oxaliplatin resistance in colorectal cancer cells by regulating HDAC2 expression.Oncol Rep. 2019 Oct;42(4):1404-1412. doi: 10.3892/or.2019.7259. Epub 2019 Aug 2.
• [2053] Flightless I homolog negatively regulates ChREBP activity in cancer cells.Int J Biochem Cell Biol. 2013 Nov;45(11):2688-97. doi: 10.1016/j.biocel.2013.09.004. Epub 2013 Sep 17.
• [2054] Clinical significance and comparison of flotillin 1 expression in left and right colon cancer.Oncol Lett. 2019 Aug;18(2):997-1004. doi: 10.3892/ol.2019.10401. Epub 2019 May 27.
• [2055] Fms-like tyrosine kinase 3 receptor ligand (Flt3L)-based vaccination administered with an adenoviral vector prevents tumor growth of colorectal cancer in a BALB/c mouse model.J Cancer Res Clin Oncol. 2013 Dec;139(12):2097-110. doi: 10.1007/s00432-013-1532-z. Epub 2013 Oct 10.
• [2056] FLYWCH1, a Novel Suppressor of Nuclear -Catenin, Regulates Migration and Morphology in Colorectal Cancer.Mol Cancer Res. 2018 Dec;16(12):1977-1990. doi: 10.1158/1541-7786.MCR-18-0262. Epub 2018 Aug 10.
• [2057] Involvement of methylation-associated silencing of formin 2 in colorectal carcinogenesis.World J Gastroenterol. 2018 Nov 28;24(44):5013-5024. doi: 10.3748/wjg.v24.i44.5013.
• [2058] A novel long noncoding RNA, LINC00483 promotes proliferation and metastasis via modulating of FMNL2 in CRC.Biochem Biophys Res Commun. 2019 Feb 5;509(2):441-447. doi: 10.1016/j.bbrc.2018.12.090. Epub 2018 Dec 26.
• [2059] Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development.J Pathol. 2015 Jun;236(2):155-64. doi: 10.1002/path.4520. Epub 2015 Mar 26.
• [2060] ForkheadboxA1 regulates tumor cell growth and predicts prognosis in colorectal cancer.Int J Oncol. 2019 Jun;54(6):2169-2178. doi: 10.3892/ijo.2019.4771. Epub 2019 Apr 4.
• [2061] FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53.Carcinogenesis. 2020 Sep 24;41(9):1253-1262. doi: 10.1093/carcin/bgz198.
• [2062] FOXD4 induces tumor progression in colorectal cancer by regulation of the SNAI3/CDH1 axis.Cancer Biol Ther. 2018;19(11):1065-1071. doi: 10.1080/15384047.2018.1480291. Epub 2018 Sep 25.
• [2063] Aberrant Methylation of FOXE1 Contributes to a Poor Prognosis for Patients with Colorectal Cancer.Ann Surg Oncol. 2016 Nov;23(12):3948-3955. doi: 10.1245/s10434-016-5289-x. Epub 2016 Jun 6.
• [2064] MicroRNA-130a is upregulated in colorectal cancer and promotes cell growth and motility by directly targeting forkhead box F2.Mol Med Rep. 2017 Oct;16(4):5241-5248. doi: 10.3892/mmr.2017.7257. Epub 2017 Aug 16.
• [2065] FAST1 promotes the migration and invasion of colorectal cancer cells.Biochem Biophys Res Commun. 2019 Feb 5;509(2):407-413. doi: 10.1016/j.bbrc.2018.12.122. Epub 2018 Dec 26.
• [2066] Forkhead Box Protein J1 (FOXJ1) is Overexpressed in Colorectal Cancer and Promotes Nuclear Translocation of -Catenin in SW620 Cells.Med Sci Monit. 2017 Feb 17;23:856-866. doi: 10.12659/msm.902906.
• [2067] Hsa_circRNA_103809 regulated the cell proliferation and migration in colorectal cancer via miR-532-3p / FOXO4 axis.Biochem Biophys Res Commun. 2018 Oct 28;505(2):346-352. doi: 10.1016/j.bbrc.2018.09.073. Epub 2018 Sep 22.
• [2068] MiR-9-5p suppresses cell metastasis and epithelial-mesenchymal transition through targeting FOXP2 and predicts prognosis of colorectal carcinoma.Eur Rev Med Pharmacol Sci. 2019 Aug;23(15):6467-6477. doi: 10.26355/eurrev_201908_18530.
• [2069] miR-1-3p suppresses proliferation of hepatocellular carcinoma through targeting SOX9.Onco Targets Ther. 2019 Mar 22;12:2149-2157. doi: 10.2147/OTT.S197326. eCollection 2019.
• [2070] 17-Hydroxysteroid dehydrogenase type 10 predicts survival of patients with colorectal cancer and affects mitochondrial DNA content.Cancer Lett. 2016 Apr 28;374(1):149-155. doi: 10.1016/j.canlet.2016.02.011. Epub 2016 Feb 13.
• [2071] Ferritin Light Chain (FTL) competes with long noncoding RNA Linc00467 for miR-133b binding site to regulate chemoresistance and metastasis of colorectal cancer.Carcinogenesis. 2020 Jun 17;41(4):467-477. doi: 10.1093/carcin/bgz181.
• [2072] Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE.Biochem Pharmacol. 2017 Dec 15;146:53-62. doi: 10.1016/j.bcp.2017.10.003. Epub 2017 Oct 13.
• [2073] Decreased expression of alpha-L-fucosidase gene FUCA1 in human colorectal tumors.Int J Mol Sci. 2013 Aug 19;14(8):16986-98. doi: 10.3390/ijms140816986.
• [2074] POFUT1 as a Promising Novel Biomarker of Colorectal Cancer.Cancers (Basel). 2018 Oct 30;10(11):411. doi: 10.3390/cancers10110411.
• [2075] Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.PLoS One. 2014 Jun 18;9(6):e97923. doi: 10.1371/journal.pone.0097923. eCollection 2014.
• [2076] miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.Cell Death Dis. 2017 Aug 3;8(8):e2968. doi: 10.1038/cddis.2017.352.
• [2077] Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer.PLoS One. 2018 Jul 5;13(7):e0200315. doi: 10.1371/journal.pone.0200315. eCollection 2018.
• [2078] An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer.Mol Syst Biol. 2017 Dec 1;13(12):956. doi: 10.15252/msb.20177739.
• [2079] FXR1 is elevated in colorectal cancer and acts as an oncogene.Tumour Biol. 2016 Feb;37(2):2683-90. doi: 10.1007/s13277-015-4068-9. Epub 2015 Sep 24.
• [2080] Expression of FXYD3 protein in relation to biological and clinicopathological variables in colorectal cancers.Chemotherapy. 2009;55(6):407-13. doi: 10.1159/000263227. Epub 2009 Dec 2.
• [2081] CircRNA_100290 promotes colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/-catenin signaling.Biochem Biophys Res Commun. 2018 Sep 26;504(1):184-189. doi: 10.1016/j.bbrc.2018.08.152. Epub 2018 Aug 30.
• [2082] MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8.Oncotarget. 2016 Jun 28;7(26):40644-40656. doi: 10.18632/oncotarget.9811.
• [2083] MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2.Oncol Rep. 2018 Jul;40(1):554-564. doi: 10.3892/or.2018.6449. Epub 2018 May 17.
• [2084] Gab3 is required for human colorectal cancer cell proliferation.Biochem Biophys Res Commun. 2017 Mar 18;484(4):719-725. doi: 10.1016/j.bbrc.2017.01.095. Epub 2017 Jan 20.
• [2085] A miRNAs panel promotes the proliferation and invasion ofcolorectal cancer cells by targeting GABBR1.Cancer Med. 2016 Aug;5(8):2022-31. doi: 10.1002/cam4.760. Epub 2016 May 27.
• [2086] CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.PLoS One. 2017 Jan 9;12(1):e0168989. doi: 10.1371/journal.pone.0168989. eCollection 2017.
• [2087] LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1.Cell Death Dis. 2018 Jun 18;9(7):722. doi: 10.1038/s41419-018-0759-7.
• [2088] Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes.Int J Cancer. 2016 Apr 15;138(8):1928-35. doi: 10.1002/ijc.29948. Epub 2015 Dec 28.
• [2089] Oncogenic BRAFV600E drives expression of MGL ligands in the colorectal cancer cell line HT29 through N-acetylgalactosamine-transferase 3.Biol Chem. 2018 Jun 27;399(7):649-659. doi: 10.1515/hsz-2018-0120.
• [2090] The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation.FEBS J. 2018 Aug;285(16):3041-3055. doi: 10.1111/febs.14593. Epub 2018 Jul 7.
• [2091] miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.Clin Cancer Res. 2017 Sep 1;23(17):5255-5266. doi: 10.1158/1078-0432.CCR-17-0023. Epub 2017 May 22.
• [2092] GALNT6 suppresses progression of colorectal cancer.Am J Cancer Res. 2018 Dec 1;8(12):2419-2435. eCollection 2018.
• [2093] Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma.Mol Cancer Res. 2016 Sep;14(9):830-40. doi: 10.1158/1541-7786.MCR-16-0032. Epub 2016 Jul 11.
• [2094] Upregulation of the growth arrest-specific-2 in recurrent colorectal cancers, and its susceptibility to chemotherapy in a model cell system.Biochim Biophys Acta. 2016 Jul;1862(7):1345-53. doi: 10.1016/j.bbadis.2016.04.010. Epub 2016 Apr 13.
• [2095] DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia.Epigenetics. 2014 Apr;9(4):503-12. doi: 10.4161/epi.27644. Epub 2014 Jan 17.
• [2096] LncRNA GAS8-AS inhibits colorectal cancer (CRC) cell proliferation by downregulating lncRNA AFAP1-AS1.Gene. 2019 Aug 20;710:140-144. doi: 10.1016/j.gene.2019.05.040. Epub 2019 May 24.
• [2097] miR-455 Functions as a Tumor Suppressor Through Targeting GATA6 in Colorectal Cancer.Oncol Res. 2019 Feb 21;27(3):311-316. doi: 10.3727/096504018X15220579006875. Epub 2018 Apr 3.
• [2098] Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer.Oncology. 2014;87(5):280-92. doi: 10.1159/000365593. Epub 2014 Aug 15.
• [2099] Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report.Cell Oncol (Dordr). 2014 Dec;37(6):455-61. doi: 10.1007/s13402-014-0209-1. Epub 2014 Dec 2.
• [2100] Aberrant methylation of GCNT2 is tightly related to lymph node metastasis of primary CRC.Anticancer Res. 2015 Mar;35(3):1411-21.
• [2101] The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance.Sci Rep. 2018 May 31;8(1):8485. doi: 10.1038/s41598-018-26468-4.
• [2102] GDPD5, a target of miR-195-5p, is associated with metastasis and chemoresistance in colorectal cancer.Biomed Pharmacother. 2018 May;101:945-952. doi: 10.1016/j.biopha.2018.03.028. Epub 2018 Mar 22.
• [2103] Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2--catenin axis.Oncotarget. 2016 Apr 5;7(14):17870-84. doi: 10.18632/oncotarget.7554.
• [2104] Twa1/Gid8 is a -catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis.Cell Res. 2017 Dec;27(12):1422-1440. doi: 10.1038/cr.2017.107. Epub 2017 Aug 22.
• [2105] Partner of Sld five 3: a potential prognostic biomarker for colorectal cancer.Diagn Pathol. 2014 Nov 18;9:217. doi: 10.1186/s13000-014-0217-5.
• [2106] Therapeutic implications of GIPC1 silencing in cancer.PLoS One. 2010 Dec 30;5(12):e15581. doi: 10.1371/journal.pone.0015581.
• [2107] Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes.Cancer Sci. 2013 Mar;104(3):328-36. doi: 10.1111/cas.12073. Epub 2013 Jan 10.
• [2108] Expression of thioredoxins and glutaredoxins in human hepatocellular carcinoma: correlation to cell proliferation, tumor size and metabolic syndrome.Int J Immunopathol Pharmacol. 2014 Apr-Jun;27(2):169-83. doi: 10.1177/039463201402700204.
• [2109] Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers.Oncotarget. 2018 May 1;9(33):22895-22906. doi: 10.18632/oncotarget.25112. eCollection 2018 May 1.
• [2110] Cerebellins are differentially expressed in selective subsets of neurons throughout the brain.J Comp Neurol. 2017 Oct 15;525(15):3286-3311. doi: 10.1002/cne.24278. Epub 2017 Jul 24.
• [2111] Expression of glia maturation factor is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.Oncol Rep. 2017 Feb;37(2):929-936. doi: 10.3892/or.2017.5361. Epub 2017 Jan 9.
• [2112] miRNA-30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene.Exp Ther Med. 2019 Jan;17(1):260-272. doi: 10.3892/etm.2018.6902. Epub 2018 Oct 30.
• [2113] A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-B-Snail circuit.J Exp Clin Cancer Res. 2016 Dec 3;35(1):187. doi: 10.1186/s13046-016-0467-z.
• [2114] Association of GNB4 intron-1 haplotypes with survival in patients with UICC stage III and IV colorectal carcinoma.Anticancer Res. 2009 Apr;29(4):1271-4.
• [2115] Therapeutic Targeting of Golgi Phosphoprotein 2 (GOLPH2) with Armed Antibodies: A Preclinical Study of Anti-GOLPH2 Antibody Drug Conjugates in Lung and Colorectal Cancer Models of Patient Derived Xenografts (PDX).Target Oncol. 2019 Oct;14(5):577-590. doi: 10.1007/s11523-019-00667-z.
• [2116] MiR-3150b-3p inhibits the progression of colorectal cancer cells via targeting GOLPH3.J Investig Med. 2020 Feb;68(2):425-429. doi: 10.1136/jim-2019-001124. Epub 2019 Nov 2.
• [2117] Nuclear Expression of GS28 Protein: A Novel Biomarker that Predicts Prognosis in Colorectal Cancers.Int J Med Sci. 2017 Apr 9;14(6):515-522. doi: 10.7150/ijms.19368. eCollection 2017.
• [2118] MAGP2, a Component of Extracellular Matrix, Is Upregulated in Colorectal Cancer and Negatively Modulated by miR-200b-3p.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819870777. doi: 10.1177/1533033819870777.
• [2119] Enhanced expression and significance of glycosylphosphatidylinositol anchor attachment protein 1 in colorectal cancer.Genet Mol Res. 2014 Jan 21;13(1):499-507. doi: 10.4238/2014.January.21.19.
• [2120] Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.Int J Cancer. 2017 Jun 15;140(12):2728-2733. doi: 10.1002/ijc.30687. Epub 2017 Mar 28.
• [2121] High levels of serum glypican-1 indicate poor prognosis in pancreatic ductal adenocarcinoma.Cancer Med. 2018 Nov;7(11):5525-5533. doi: 10.1002/cam4.1833. Epub 2018 Oct 24.
• [2122] CD36 inhibits -catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.Nat Commun. 2019 Sep 4;10(1):3981. doi: 10.1038/s41467-019-11662-3.
• [2123] DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/-catenin signaling pathway genes.Epigenomics. 2014 Apr;6(2):179-91. doi: 10.2217/epi.14.7.
• [2124] Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.Nat Genet. 2012 May 27;44(7):770-6. doi: 10.1038/ng.2293.
• [2125] Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway.EBioMedicine. 2019 Oct;48:264-276. doi: 10.1016/j.ebiom.2019.09.016. Epub 2019 Sep 14.
• [2126] Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets.Oncotarget. 2017 Oct 20;8(59):99913-99930. doi: 10.18632/oncotarget.21915. eCollection 2017 Nov 21.
• [2127] Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.Nat Commun. 2016 Jun 20;7:11971. doi: 10.1038/ncomms11971.
• [2128] GPX3 promoter methylation predicts platinum sensitivity in colorectal cancer.Epigenetics. 2017 Jul 3;12(7):540-550. doi: 10.1080/15592294.2016.1265711. Epub 2016 Dec 5.
• [2129] RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer.Front Pharmacol. 2018 Nov 22;9:1371. doi: 10.3389/fphar.2018.01371. eCollection 2018.
• [2130] High expression of growth factor receptor-bound protein 14 predicts poor prognosis for colorectal cancer patients.Biotechnol Lett. 2016 Jun;38(6):1043-7. doi: 10.1007/s10529-016-2077-4. Epub 2016 Mar 10.
• [2131] Overexpression of GRK6 associates with the progression and prognosis of colorectal carcinoma.Oncol Lett. 2018 Apr;15(4):5879-5886. doi: 10.3892/ol.2018.8030. Epub 2018 Feb 12.
• [2132] Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.PLoS One. 2016 Nov 11;11(11):e0166422. doi: 10.1371/journal.pone.0166422. eCollection 2016.
• [2133] Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer.Cancer Med. 2019 May;8(5):2133-2145. doi: 10.1002/cam4.2103. Epub 2019 Apr 16.
• [2134] Identification of candidate genes carrying polymorphisms associated with the risk of colorectal cancer by analyzing the colorectal mutome and microRNAome.Cancer. 2012 Oct 1;118(19):4670-80. doi: 10.1002/cncr.27435. Epub 2012 Jan 26.
• [2135] miRNA-144 suppresses proliferation and migration of colorectal cancer cells through GSPT1.Biomed Pharmacother. 2015 Aug;74:138-44. doi: 10.1016/j.biopha.2015.08.006. Epub 2015 Aug 13.
• [2136] Association of glutathione S-transferase M1 polymorphisms in the colorectal cancer risk: A meta-analysis.J Cancer Res Ther. 2018 Jan;14(1):176-183. doi: 10.4103/jcrt.JCRT_446_16.
• [2137] First-line cetuximab plus capecitabine in elderly patients with advanced colorectal cancer: clinical outcome and subgroup analysis according to KRAS status from a Spanish TTD Group Study.Oncologist. 2012;17(3):339-45. doi: 10.1634/theoncologist.2011-0406. Epub 2012 Feb 23.
• [2138] Up-regulation of GTPBP4 in colorectal carcinoma is responsible for tumor metastasis.Biochem Biophys Res Commun. 2016 Nov 4;480(1):48-54. doi: 10.1016/j.bbrc.2016.10.010. Epub 2016 Oct 5.
• [2139] Intestinal GUCY2C prevents TGF- secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.Cancer Res. 2013 Nov 15;73(22):6654-66. doi: 10.1158/0008-5472.CAN-13-0887. Epub 2013 Oct 1.
• [2140] Coexpression network analysis linked H2AFJ to chemoradiation resistance in colorectal cancer.J Cell Biochem. 2019 Jun;120(6):10351-10362. doi: 10.1002/jcb.28319. Epub 2018 Dec 19.
• [2141] Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancer.Oncotarget. 2017 Oct 20;9(12):10247-10258. doi: 10.18632/oncotarget.21908. eCollection 2018 Feb 13.
• [2142] Integrated analyses of multi-omics reveal global patterns of methylation and hydroxymethylation and screen the tumor suppressive roles of HADHB in colorectal cancer.Clin Epigenetics. 2018 Mar 2;10:30. doi: 10.1186/s13148-018-0458-3. eCollection 2018.
• [2143] Hyaluronic acid synthase 2 promotes malignant phenotypes of colorectal cancer cells through transforming growth factor beta signaling.Cancer Sci. 2019 Jul;110(7):2226-2236. doi: 10.1111/cas.14070. Epub 2019 Jun 12.
• [2144] HAVcR-1 expression in human colorectal cancer and its effects on colorectal cancer cells in vitro.Anticancer Res. 2013 Jan;33(1):207-14.
• [2145] Down-regulated expression of Tim-3 promotes invasion and metastasis of colorectal cancer cells.Neoplasma. 2017;64(1):101-107. doi: 10.4149/neo_2017_112.
• [2146] MicroRNA-155 enhances the activation of Wnt/-catenin signaling in colorectal carcinoma by suppressing HMG-box transcription factor 1.Mol Med Rep. 2016 Mar;13(3):2221-8. doi: 10.3892/mmr.2016.4788. Epub 2016 Jan 15.
• [2147] Amplified in breast cancer 1 promotes colorectal cancer progression through enhancing notch signaling.Oncogene. 2015 Jul 23;34(30):3935-3945. doi: 10.1038/onc.2014.324. Epub 2014 Sep 29.
• [2148] Overexpression of Hepatocyte Cell Adhesion Molecule (hepaCAM) Inhibits the Proliferation, Migration, and Invasion in Colorectal Cancer Cells.Oncol Res. 2017 Aug 7;25(7):1039-1046. doi: 10.3727/096504016X14813914187138. Epub 2016 Dec 15.
• [2149] Hes1 is associated with long non-coding RNAs in colorectal cancer.Ann Transl Med. 2019 Sep;7(18):459. doi: 10.21037/atm.2019.08.11.
• [2150] Overexpression of HES6 has prognostic value and promotes metastasis via the Wnt/-catenin signaling pathway in colorectal cancer.Oncol Rep. 2018 Sep;40(3):1261-1274. doi: 10.3892/or.2018.6539. Epub 2018 Jul 2.
• [2151] MiR-769 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Targeting HEY1.Med Sci Monit. 2018 Dec 19;24:9232-9239. doi: 10.12659/MSM.911663.
• [2152] The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo.BMC Cancer. 2019 Dec 3;19(1):1181. doi: 10.1186/s12885-019-6396-4.
• [2153] Rates of Actionable Genetic Findings in Individuals with Colorectal Cancer or Polyps Ascertained from a Community Medical Setting.Am J Hum Genet. 2019 Sep 5;105(3):526-533. doi: 10.1016/j.ajhg.2019.07.012. Epub 2019 Aug 15.
• [2154] Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma.Onco Targets Ther. 2018 Mar 20;11:1563-1570. doi: 10.2147/OTT.S160493. eCollection 2018.
• [2155] Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer.Cell Death Dis. 2019 Aug 13;10(8):618. doi: 10.1038/s41419-019-1832-6.
• [2156] HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.Cancer Lett. 2013 Dec 1;341(2):159-65. doi: 10.1016/j.canlet.2013.07.028. Epub 2013 Aug 2.
• [2157] HINT2 downregulation promotes colorectal carcinoma migration and metastasis.Oncotarget. 2017 Feb 21;8(8):13521-13531. doi: 10.18632/oncotarget.14587.
• [2158] HIPK1 drives p53 activation to limit colorectal cancer cell growth.Cell Cycle. 2013 Jun 15;12(12):1879-91. doi: 10.4161/cc.24927. Epub 2013 May 15.
• [2159] Association of cytotoxic T-lymphocyte antigen 4 rs231775 gene polymorphism with colorectal cancer risk.J Cancer Res Ther. 2018 Jun;14(Supplement):S526-S532. doi: 10.4103/0973-1482.191065.
• [2160] Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population.Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):108-12.
• [2161] Clinicopathological significance of human leukocyte antigen F-associated transcript 10 expression in colorectal cancer.World J Gastrointest Oncol. 2019 Jan 15;11(1):9-16. doi: 10.4251/wjgo.v11.i1.9.
• [2162] The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer.Oncotarget. 2017 Aug 3;8(41):70617-70629. doi: 10.18632/oncotarget.19904. eCollection 2017 Sep 19.
• [2163] Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel.Int Immunopharmacol. 2016 Nov;40:428-435. doi: 10.1016/j.intimp.2016.09.022. Epub 2016 Sep 30.
• [2164] LINC01354 interacting with hnRNP-D contributes to the proliferation and metastasis in colorectal cancer through activating Wnt/-catenin signaling pathway.J Exp Clin Cancer Res. 2019 Apr 15;38(1):161. doi: 10.1186/s13046-019-1150-y.
• [2165] Heterogeneous nuclear ribonucleoprotein L facilitates recruitment of 53BP1 and BRCA1 at the DNA break sites induced by oxaliplatin in colorectal cancer.Cell Death Dis. 2019 Jul 18;10(8):550. doi: 10.1038/s41419-019-1784-x.
• [2166] hnRNPM induces translation switch under hypoxia to promote colon cancer development.EBioMedicine. 2019 Mar;41:299-309. doi: 10.1016/j.ebiom.2019.02.059. Epub 2019 Mar 7.
• [2167] Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.Cell Death Dis. 2017 Jun 8;8(6):e2862. doi: 10.1038/cddis.2017.258.
• [2168] Upregulation of HOXA10 Protein Expression Predicts Poor Prognosis for Colorectal Cancer.Genet Test Mol Biomarkers. 2018 Jun;22(6):390-397. doi: 10.1089/gtmb.2017.0240. Epub 2018 Jun 5.
• [2169] Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines.Biochem Biophys Res Commun. 2000 Jun 7;272(2):513-8. doi: 10.1006/bbrc.2000.2804.
• [2170] Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1.Oncogene. 2020 Jan;39(5):1004-1017. doi: 10.1038/s41388-019-1013-1. Epub 2019 Oct 7.
• [2171] Homeobox B9 Mediates Resistance to Anti-VEGF Therapy in Colorectal Cancer Patients.Clin Cancer Res. 2017 Aug 1;23(15):4312-4322. doi: 10.1158/1078-0432.CCR-16-3153. Epub 2017 Mar 15.
• [2172] Soluble PD-1-based vaccine targeting MUC1 VNTR and survivin improves anti-tumor effect.Immunol Lett. 2018 Aug;200:33-42. doi: 10.1016/j.imlet.2018.06.004. Epub 2018 Jun 9.
• [2173] HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer.Int J Biochem Cell Biol. 2017 Jul;88:1-13. doi: 10.1016/j.biocel.2017.04.011. Epub 2017 Apr 27.
• [2174] Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma.Int J Cancer. 2013 Jan 15;132(2):297-307. doi: 10.1002/ijc.27674. Epub 2012 Jun 28.
• [2175] HRG/HER2/HER3 signaling promotes AhR-mediated Memo-1 expression and migration in colorectal cancer.Oncogene. 2017 Apr 27;36(17):2394-2404. doi: 10.1038/onc.2016.390. Epub 2016 Dec 12.
• [2176] High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer.IUBMB Life. 2017 Dec;69(12):956-961. doi: 10.1002/iub.1692. Epub 2017 Nov 13.
• [2177] Polymorphisms of PRLHR and HSPA12A and risk of gastric and colorectal cancer in the Chinese Han population.BMC Gastroenterol. 2015 Aug 25;15:107. doi: 10.1186/s12876-015-0336-9.
• [2178] Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth.BMC Cancer. 2016 Jul 29;16:561. doi: 10.1186/s12885-016-2592-7.
• [2179] Therapeutic potency of heat-shock protein-70 in the pathogenesis of colorectal cancer: current status and perspectives.Biochem Cell Biol. 2019 Apr;97(2):85-90. doi: 10.1139/bcb-2018-0177. Epub 2018 Oct 1.
• [2180] Heat shock protein 27 knockdown using nucleotidebased therapies enhances sensitivity to 5-FU chemotherapy in SW480 human colon cancer cells.Oncol Rep. 2018 Mar;39(3):1119-1124. doi: 10.3892/or.2018.6180. Epub 2018 Jan 3.
• [2181] Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.J Cell Biochem. 2015 Feb;116(2):277-86. doi: 10.1002/jcb.24966.
• [2182] Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.Cell Death Differ. 2020 Jan;27(1):117-129. doi: 10.1038/s41418-019-0343-4. Epub 2019 May 8.
• [2183] HtrA3 stromal expression is correlated with tumor budding in stage II colorectal cancer.Exp Mol Pathol. 2017 Aug;103(1):94-100. doi: 10.1016/j.yexmp.2017.07.002. Epub 2017 Jul 15.
• [2184] Meta-analysis of gene expression alterations and clinical significance of the HECT domain-containing ubiquitin ligase HUWE1 in cancer.Oncol Lett. 2019 Sep;18(3):2292-2303. doi: 10.3892/ol.2019.10579. Epub 2019 Jul 5.
• [2185] Overexpression of insulin receptor substrate-4 is correlated with clinical staging in colorectal cancer patients.J Mol Histol. 2018 Feb;49(1):39-49. doi: 10.1007/s10735-017-9745-0. Epub 2017 Nov 28.
• [2186] Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer.Biochem Biophys Res Commun. 2016 Jan 15;469(3):430-6. doi: 10.1016/j.bbrc.2015.09.109. Epub 2015 Dec 17.
• [2187] Immediate early response gene X-1, a potential prognostic biomarker in cancers.Expert Opin Ther Targets. 2013 May;17(5):593-606. doi: 10.1517/14728222.2013.768234. Epub 2013 Feb 4.
• [2188] IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer.Cancer Sci. 2019 Apr;110(4):1293-1305. doi: 10.1111/cas.13964. Epub 2019 Mar 22.
• [2189] Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers.Oncotarget. 2016 May 10;7(19):28027-39. doi: 10.18632/oncotarget.8473.
• [2190] Insulin-like growth factor binding protein-4 gene therapy increases apoptosis by altering Bcl-2 and Bax proteins and decreases angiogenesis in colorectal cancer.Int J Oncol. 2007 Apr;30(4):883-8.
• [2191] Influence of components of tumour microenvironment on the response of HCT-116 colorectal cancer to the ruthenium-based drug NAMI-A.J Inorg Biochem. 2017 Mar;168:90-97. doi: 10.1016/j.jinorgbio.2016.11.031. Epub 2016 Dec 2.
• [2192] Hyper activation of -catenin signalling induced by IKK inhibition thwarts colorectal cancer cell proliferation.Cell Prolif. 2017 Aug;50(4):e12350. doi: 10.1111/cpr.12350. Epub 2017 May 19.
• [2193] The expression of IL10RA in colorectal cancer and its correlation with the proliferation index and the clinical stage of the disease.Cytokine. 2018 Oct;110:116-125. doi: 10.1016/j.cyto.2018.04.030. Epub 2018 May 3.
• [2194] Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue.Oncotarget. 2017 Dec 15;9(3):3432-3445. doi: 10.18632/oncotarget.23289. eCollection 2018 Jan 9.
• [2195] YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648. doi: 10.1073/pnas.1620290114. Epub 2017 Jan 27.
• [2196] Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.J Clin Oncol. 2016 Jun 20;34(18):2141-7. doi: 10.1200/JCO.2015.65.1067. Epub 2016 Mar 28.
• [2197] Genetic alterations and expression of inhibitor of growth 1 in human sporadic colorectal cancer.World J Gastroenterol. 2005 Oct 21;11(39):6120-4. doi: 10.3748/wjg.v11.i39.6120.
• [2198] ING2, a tumor associated gene, enhances PAI? and HSPA1A expression with HDAC1 and mSin3A through the PHD domain and Cterminal.Mol Med Rep. 2017 Nov;16(5):7367-7374. doi: 10.3892/mmr.2017.7553. Epub 2017 Sep 20.
• [2199] Long non-coding RNA FENDRR restrains the aggressiveness of CRC via regulating miR-18a-5p/ING4 axis.J Cell Biochem. 2020 Aug;121(8-9):3973-3985. doi: 10.1002/jcb.29555. Epub 2019 Nov 13.
• [2200] Integrated analysis of genes associated with poor prognosis of patients with colorectal cancer liver metastasis.Oncotarget. 2017 Apr 11;8(15):25500-25512. doi: 10.18632/oncotarget.16064.
• [2201] Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation.Oncotarget. 2016 Nov 8;7(45):73525-73540. doi: 10.18632/oncotarget.12321.
• [2202] Insulin-induced gene 2 expression correlates with colorectal cancer metastasis and disease outcome.IUBMB Life. 2016 Jan;68(1):65-71. doi: 10.1002/iub.1461. Epub 2015 Dec 10.
• [2203] Hospitalization Rates and Predictors of Rehospitalization Among Individuals With Advanced Cancer in the Year After Diagnosis.J Clin Oncol. 2017 Nov 1;35(31):3610-3617. doi: 10.1200/JCO.2017.72.4963. Epub 2017 Aug 29.
• [2204] Increased DNA integrity in colorectal cancer.In Vivo. 2014 May-Jun;28(3):299-303.
• [2205] IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.J Exp Clin Cancer Res. 2019 Jul 9;38(1):296. doi: 10.1186/s13046-019-1290-0.
• [2206] Long non-coding RNA IQCJ-SCHIP1 antisense RNA 1 is downregulated in colorectal cancer and inhibits cell proliferation.Ann Transl Med. 2019 May;7(9):198. doi: 10.21037/atm.2019.04.21.
• [2207] miR?24 inhibits cell growth through targeting IQGAP1 in colorectal cancer.Mol Med Rep. 2018 Dec;18(6):5270-5278. doi: 10.3892/mmr.2018.9518. Epub 2018 Sep 27.
• [2208] Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.PLoS One. 2017 Oct 26;12(10):e0186977. doi: 10.1371/journal.pone.0186977. eCollection 2017.
• [2209] A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.J Biol Chem. 2014 Aug 15;289(33):23123-23131. doi: 10.1074/jbc.M113.492934. Epub 2014 Jun 19.
• [2210] Colorectal cancer exosomes induce lymphatic network remodeling in lymph nodes.Int J Cancer. 2019 Sep 15;145(6):1648-1659. doi: 10.1002/ijc.32196. Epub 2019 Feb 20.
• [2211] Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.PLoS One. 2014 Oct 28;9(10):e111061. doi: 10.1371/journal.pone.0111061. eCollection 2014.
• [2212] Trapping of Lipopolysaccharide to Promote Immunotherapy against Colorectal Cancer and Attenuate Liver Metastasis.Adv Mater. 2018 Dec;30(52):e1805007. doi: 10.1002/adma.201805007. Epub 2018 Nov 2.
• [2213] IRX5 promotes colorectal cancer metastasis by negatively regulating the core components of the RHOA pathway.Mol Carcinog. 2019 Nov;58(11):2065-2076. doi: 10.1002/mc.23098. Epub 2019 Aug 20.
• [2214] Knockdown of ISOC1 inhibits the proliferation and migration and induces the apoptosis of colon cancer cells through the AKT/GSK-3 pathway.Carcinogenesis. 2020 Aug 12;41(8):1123-1133. doi: 10.1093/carcin/bgz188.
• [2215] Novel chemosensitive single-nucleotide polymorphism markers to targeted regimens in metastatic colorectal cancer. Clin Cancer Res. 2011 Mar 1;17(5):1200-9.
• [2216] Downregulation of serum metabolite GTA-446 as a novel potential marker for early detection of colorectal cancer.Br J Cancer. 2017 Jul 11;117(2):227-232. doi: 10.1038/bjc.2017.163. Epub 2017 Jun 20.
• [2217] Altered frequency of CD8(+) CD11c(+) T cells and expression of immunosuppressive molecules in lymphoid organs of mouse model of colorectal cancer.J Cell Physiol. 2019 Jul;234(7):11986-11998. doi: 10.1002/jcp.27856. Epub 2019 Jan 8.
• [2218] KRAS-induced actin-interacting protein: a potent target for obesity, diabetes and cancer.Anticancer Res. 2011 Jul;31(7):2413-7.
• [2219] Identification of LEA, a podocalyxin-like glycoprotein, as a predictor for the progression of colorectal cancer.Cancer Med. 2018 Oct;7(10):5155-5166. doi: 10.1002/cam4.1765. Epub 2018 Sep 12.
• [2220] NSD2 circular RNA promotes metastasis of colorectal cancer by targeting miR-199b-5p-mediated DDR1 and JAG1 signalling.J Pathol. 2019 May;248(1):103-115. doi: 10.1002/path.5238. Epub 2019 Feb 20.
• [2221] JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer.Cancer Manag Res. 2019 Mar 27;11:2457-2470. doi: 10.2147/CMAR.S189937. eCollection 2019.
• [2222] MiR-873-5p suppresses cell proliferation and epithelial-mesenchymal transition via directly targeting Jumonji domain-containing protein 8 through the NF-B pathway in colorectal cancer.J Cell Commun Signal. 2019 Dec;13(4):549-560. doi: 10.1007/s12079-019-00522-w. Epub 2019 May 31.
• [2223] Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma.Sci Rep. 2019 Nov 20;9(1):17178. doi: 10.1038/s41598-019-52841-y.
• [2224] JRK is a positive regulator of -catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.Oncogene. 2016 Jun 2;35(22):2834-41. doi: 10.1038/onc.2015.347. Epub 2015 Oct 12.
• [2225] A novel long non-coding RNA-KAT7 is low expressed in colorectal cancer and acts as a tumor suppressor.Cancer Cell Int. 2019 Feb 26;19:40. doi: 10.1186/s12935-019-0760-y. eCollection 2019.
• [2226] Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma.Int J Oncol. 2014 Apr;44(4):1207-14. doi: 10.3892/ijo.2014.2266. Epub 2014 Jan 21.
• [2227] A polymorphic MYC response element in KBTBD11 influences colorectal cancer risk, especially in interaction with an MYC-regulated SNP rs6983267.Ann Oncol. 2018 Mar 1;29(3):632-639. doi: 10.1093/annonc/mdx789.
• [2228] An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer.Gut. 2013 Apr;62(4):571-81. doi: 10.1136/gutjnl-2011-301059. Epub 2012 Feb 16.
• [2229] Histone Demethylase JMJD2D Interacts With -Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.Gastroenterology. 2019 Mar;156(4):1112-1126. doi: 10.1053/j.gastro.2018.11.036. Epub 2018 Nov 23.
• [2230] A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.EBioMedicine. 2017 Jun;20:39-49. doi: 10.1016/j.ebiom.2017.04.022. Epub 2017 Apr 13.
• [2231] KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway.Aging (Albany NY). 2019 Dec 16;11(24):11905-11921. doi: 10.18632/aging.102505. Epub 2019 Dec 16.
• [2232] KIF2A overexpression and its association with clinicopathologic characteristics and unfavorable prognosis in colorectal cancer.Tumour Biol. 2015 Nov;36(11):8895-902. doi: 10.1007/s13277-015-3603-z. Epub 2015 Jun 13.
• [2233] Evidence of colorectal cancer-associated mutation in MCAK: a computational report.Cell Biochem Biophys. 2013;67(3):837-51. doi: 10.1007/s12013-013-9572-1.
• [2234] LEF-AS1 participates in occurrence of colorectal cancer through adsorbing miR-505 and promoting KIF3B expression.Eur Rev Med Pharmacol Sci. 2019 Nov;23(21):9362-9370. doi: 10.26355/eurrev_201911_19429.
• [2235] Klotho suppresses colorectal cancer through modulation of the unfolded protein response.Oncogene. 2019 Feb;38(6):794-807. doi: 10.1038/s41388-018-0489-4. Epub 2018 Sep 19.
• [2236] RNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer.Oncotarget. 2017 Mar 28;8(13):21984-21993. doi: 10.18632/oncotarget.15766.
• [2237] KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2.Oncotarget. 2015 Sep 22;6(28):25402-17. doi: 10.18632/oncotarget.4517.
• [2238] Clinical significance of kallikrein-related peptidase (KLK10) mRNA expression in colorectal cancer.Clin Biochem. 2013 Oct;46(15):1453-61. doi: 10.1016/j.clinbiochem.2013.03.002. Epub 2013 Mar 13.
• [2239] Knockdown of KLK12 inhibits viability and inducesapoptosis in human colorectal cancer HT-29 cell line.Int J Mol Med. 2019 Nov;44(5):1667-1676. doi: 10.3892/ijmm.2019.4327. Epub 2019 Aug 30.
• [2240] Does a transition to accountable care in Medicaid shift the modality of colorectal cancer testing?.BMC Health Serv Res. 2019 Jan 21;19(1):54. doi: 10.1186/s12913-018-3864-5.
• [2241] Effect of KNL1 on the proliferation and apoptosis of colorectal cancer cells.Technol Cancer Res Treat. 2019 Jan 1;18:1533033819858668. doi: 10.1177/1533033819858668.
• [2242] Inhibition of Karyopherin-2 Augments Radiation-Induced Cell Death by Perturbing BRCA1-Mediated DNA Repair.Int J Mol Sci. 2019 Jun 11;20(11):2843. doi: 10.3390/ijms20112843.
• [2243] LncRNA DLEU1 contributes to colorectal cancer progression via activation of KPNA3.Mol Cancer. 2018 Aug 11;17(1):118. doi: 10.1186/s12943-018-0873-2.
• [2244] KRT18 is correlated with the malignant status and acts as an oncogene in colorectal cancer.Biosci Rep. 2019 Aug 13;39(8):BSR20190884. doi: 10.1042/BSR20190884. Print 2019 Aug 30.
• [2245] Keratin 23 promotes telomerase reverse transcriptase expression and human colorectal cancer growth.Cell Death Dis. 2017 Jul 27;8(7):e2961. doi: 10.1038/cddis.2017.339.
• [2246] Immunohistochemical staining of cytokeratin 20 and cytokeratin 7 in colorectal carcinomas: Four different immunostaining profiles.Saudi J Gastroenterol. 2018 Mar-Apr;24(2):129-134. doi: 10.4103/sjg.SJG_465_17.
• [2247] A new chalcone derivative, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)prop-2-yn-1-one), inhibits phorbol ester-induced metastatic activity of colorectal cancer cells through upregulation of heme oxygenase-1.Eur J Pharmacol. 2018 Dec 15;841:1-9. doi: 10.1016/j.ejphar.2018.10.011. Epub 2018 Oct 12.
• [2248] Externalized Keratin 8: A Target at the Interface of Microenvironment and Intracellular Signaling in Colorectal Cancer Cells.Cancers (Basel). 2018 Nov 16;10(11):452. doi: 10.3390/cancers10110452.
• [2249] Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway.Cell Death Dis. 2018 Sep 27;9(10):1009. doi: 10.1038/s41419-018-1030-y.
• [2250] Competing endogenous RNA network crosstalk reveals novel molecular markers in colorectal cancer.J Cell Biochem. 2018 Aug;119(8):6869-6881. doi: 10.1002/jcb.26884. Epub 2018 May 8.
• [2251] LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.Oncogene. 2018 Oct;37(41):5534-5551. doi: 10.1038/s41388-018-0352-7. Epub 2018 Jun 13.
• [2252] Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer.Oncogene. 2016 Jan 14;35(2):187-95. doi: 10.1038/onc.2015.72. Epub 2015 Mar 30.
• [2253] Laminin 1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma.Biol Cell. 2018 Jun 15. doi: 10.1111/boc.201800007. Online ahead of print.
• [2254] Laminin gene LAMB4 is somatically mutated and expressionally altered in gastric and colorectal cancers.APMIS. 2015 Jan;123(1):65-71. doi: 10.1111/apm.12309. Epub 2014 Sep 25.
• [2255] Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model.Int Immunopharmacol. 2017 Jan;42:122-129. doi: 10.1016/j.intimp.2016.11.017. Epub 2016 Nov 29.
• [2256] Effects of PHA-665752 and Cetuximab Combination Treatment on In Vitro and Murine Xenograft Growth of Human Colorectal Cancer Cells with KRAS or BRAF Mutations.Curr Cancer Drug Targets. 2018;18(3):278-286. doi: 10.2174/1568009617666170330112841.
• [2257] Plastin polymorphisms predict gender- and stage-specific colon cancer recurrence after adjuvant chemotherapy.Mol Cancer Ther. 2014 Feb;13(2):528-39. doi: 10.1158/1535-7163.MCT-13-0646. Epub 2013 Oct 29.
• [2258] LDB1 overexpression is a negative prognostic factor in colorectal cancer.Oncotarget. 2016 Dec 20;7(51):84258-84270. doi: 10.18632/oncotarget.12481.
• [2259] Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis.Oncotarget. 2018 Nov 23;9(92):36430-36443. doi: 10.18632/oncotarget.26335. eCollection 2018 Nov 23.
• [2260] The intestinal stem cell regulating gene ASCL2 is required for L1-mediated colon cancer progression.Cancer Lett. 2018 Jun 28;424:9-18. doi: 10.1016/j.canlet.2018.03.022. Epub 2018 Mar 15.
• [2261] Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.IUBMB Life. 2017 Dec;69(12):962-970. doi: 10.1002/iub.1690. Epub 2017 Nov 3.
• [2262] Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma.Oncotarget. 2017 Apr 4;8(14):23787-23802. doi: 10.18632/oncotarget.15865.
• [2263] DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer.Clin Epigenetics. 2018 Aug 6;10(1):104. doi: 10.1186/s13148-018-0539-3.
• [2264] Downregulation of Lgr6 inhibits proliferation and invasion and increases apoptosis in human colorectal cancer.Int J Mol Med. 2018 Jul;42(1):625-632. doi: 10.3892/ijmm.2018.3633. Epub 2018 Apr 18.
• [2265] Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population.Oxid Med Cell Longev. 2016;2016:3125989. doi: 10.1155/2016/3125989. Epub 2015 Nov 16.
• [2266] Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.Hum Mol Genet. 2014 Apr 15;23(8):2043-54. doi: 10.1093/hmg/ddt599. Epub 2013 Nov 26.
• [2267] Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.Hum Mol Genet. 2014 Sep 1;23(17):4729-37. doi: 10.1093/hmg/ddu177. Epub 2014 Apr 15.
• [2268] LMO1 is a novel oncogene in colorectal cancer and its overexpression is a new predictive marker for anti-EGFR therapy.Tumour Biol. 2014 Aug;35(8):8161-7. doi: 10.1007/s13277-014-2066-y. Epub 2014 May 21.
• [2269] High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.PLoS One. 2017 Sep 28;12(9):e0185607. doi: 10.1371/journal.pone.0185607. eCollection 2017.
• [2270] Suppression of cancer stemness by upregulating Ligand-of-Numb protein X1 in colorectal carcinoma.PLoS One. 2017 Nov 30;12(11):e0188665. doi: 10.1371/journal.pone.0188665. eCollection 2017.
• [2271] Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/-catenin pathway in colorectal cancer.Cancer Res. 2013 Mar 15;73(6):2003-13. doi: 10.1158/0008-5472.CAN-12-3159. Epub 2013 Jan 14.
• [2272] Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance.Nat Commun. 2018 Jan 22;9(1):322. doi: 10.1038/s41467-017-02732-5.
• [2273] Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4.Cancer Sci. 2013 Oct;104(10):1295-302. doi: 10.1111/cas.12221. Epub 2013 Jul 30.
• [2274] LIM protein JUB promotes epithelial-mesenchymal transition in colorectal cancer.Cancer Sci. 2014 Jun;105(6):660-6. doi: 10.1111/cas.12404. Epub 2014 May 10.
• [2275] Epigenetic silencing of LRRC3B in colorectal cancer.Scand J Gastroenterol. 2009;44(1):79-84. doi: 10.1080/00365520802400834.
• [2276] Clinical value of an adenosine triphosphate-based chemotherapy response assay in resectable stage III colorectal cancer.Ann Surg Treat Res. 2019 Aug;97(2):93-102. doi: 10.4174/astr.2019.97.2.93. Epub 2019 Jul 29.
• [2277] Expression and roles of lumican in lung adenocarcinoma and squamous cell carcinoma.Int J Oncol. 2008 Dec;33(6):1177-85.
• [2278] LYRM2 directly regulates complex I activity to support tumor growth in colorectal cancer by oxidative phosphorylation.Cancer Lett. 2019 Jul 28;455:36-47. doi: 10.1016/j.canlet.2019.04.021. Epub 2019 Apr 17.
• [2279] Prognostic and Risk Stratification Value of Lesion MACC1 Expression in Colorectal Cancer Patients.Front Oncol. 2019 Feb 5;9:28. doi: 10.3389/fonc.2019.00028. eCollection 2019.
• [2280] Genome-wide association study of colorectal cancer in Hispanics.Carcinogenesis. 2016 Jun;37(6):547-556. doi: 10.1093/carcin/bgw046. Epub 2016 Apr 18.
• [2281] Blockade of the LRP16-PKR-NF-B signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.Elife. 2017 Aug 18;6:e27301. doi: 10.7554/eLife.27301.
• [2282] High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer.PLoS One. 2015 Sep 16;10(9):e0138141. doi: 10.1371/journal.pone.0138141. eCollection 2015.
• [2283] Deficiency of 15-LOX-1 Induces Radioresistance through Downregulation of MacroH2A2 in Colorectal Cancer.Cancers (Basel). 2019 Nov 11;11(11):1776. doi: 10.3390/cancers11111776.
• [2284] MAEL expression links epithelial-mesenchymal transition and stem cell properties in colorectal cancer.Int J Cancer. 2016 Dec 1;139(11):2502-11. doi: 10.1002/ijc.30388. Epub 2016 Aug 29.
• [2285] Involvement of MAF1homolog, negative regulator of RNA polymeraseIII in colorectal cancer progression.Int J Oncol. 2019 Mar;54(3):1001-1009. doi: 10.3892/ijo.2019.4678. Epub 2019 Jan 7.
• [2286] The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype.Mol Cell. 2014 Sep 18;55(6):904-915. doi: 10.1016/j.molcel.2014.08.010. Epub 2014 Sep 11.
• [2287] The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis.PLoS One. 2017 May 31;12(5):e0178515. doi: 10.1371/journal.pone.0178515. eCollection 2017.
• [2288] Apoptosis, necroptosis and autophagy in colorectal cancer: Associations with tumor aggressiveness and p53 status.Pathol Res Pract. 2019 Jul;215(7):152425. doi: 10.1016/j.prp.2019.04.017. Epub 2019 Apr 29.
• [2289] The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients.Med Oncol. 2018 Oct 29;35(12):159. doi: 10.1007/s12032-018-1220-6.
• [2290] Overexpression of microRNA-216a inhibits autophagy by targeting regulated MAP1S in colorectal cancer.Onco Targets Ther. 2019 Jun 12;12:4621-4629. doi: 10.2147/OTT.S196992. eCollection 2019.
• [2291] MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer.Cell Death Dis. 2019 Nov 6;10(11):842. doi: 10.1038/s41419-019-2083-2.
• [2292] A cost-effectiveness analysis of a colorectal cancer screening program in safety net clinics.Prev Med. 2019 Mar;120:119-125. doi: 10.1016/j.ypmed.2019.01.014. Epub 2019 Jan 24.
• [2293] A phase Ib study of capecitabine and ziv-aflibercept followed by a phase II single-arm expansion cohort in chemotherapy refractory metastatic colorectal cancer.BMC Cancer. 2019 Nov 1;19(1):1032. doi: 10.1186/s12885-019-6234-8.
• [2294] MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.Acta Biochim Biophys Sin (Shanghai). 2019 Jul 10;51(7):661-668. doi: 10.1093/abbs/gmz047.
• [2295] MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/-catenin signaling.Mol Cancer. 2018 Aug 1;17(1):111. doi: 10.1186/s12943-018-0848-3.
• [2296] Elevation of ST6Gal I activity in malignant and transitional tissue in human colorectal cancer.Oncology. 2005;69(5):436-44. doi: 10.1159/000089999. Epub 2005 Nov 25.
• [2297] Allele-specific imbalance mapping at human orthologs of mouse susceptibility to colon cancer (Scc) loci.Int J Cancer. 2015 Nov 15;137(10):2323-31. doi: 10.1002/ijc.29599. Epub 2015 May 29.
• [2298] Right or Left Primary Site of Colorectal Cancer: Outcomes From the Molecular Analysis of the AGITG MAX Trial.Clin Colorectal Cancer. 2019 Jun;18(2):141-148. doi: 10.1016/j.clcc.2018.12.002. Epub 2019 Jan 3.
• [2299] Mutated MCM9 is associated with predisposition to hereditary mixed polyposis and colorectal cancer in addition to primary ovarian failure.Cancer Genet. 2015 Dec;208(12):621-4. doi: 10.1016/j.cancergen.2015.10.001. Epub 2015 Oct 22.
• [2300] Polymorphisms of monocarboxylate transporter genes are associated with clinical outcomes in patients with colorectal cancer.J Cancer Res Clin Oncol. 2015 Jun;141(6):1095-102. doi: 10.1007/s00432-014-1877-y. Epub 2014 Dec 10.
• [2301] MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.Asian Pac J Cancer Prev. 2012;13(7):3233-8. doi: 10.7314/apjcp.2012.13.7.3233.
• [2302] DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.Gene. 2017 Sep 30;630:1-7. doi: 10.1016/j.gene.2017.07.082. Epub 2017 Aug 4.
• [2303] Intratumoral Heterogeneity of Frameshift Mutations in MECOM Gene is Frequent in Colorectal Cancers with High Microsatellite Instability.Pathol Oncol Res. 2017 Jan;23(1):145-149. doi: 10.1007/s12253-016-0112-3. Epub 2016 Sep 13.
• [2304] Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.Oncol Rep. 2009 Jun;21(6):1455-60. doi: 10.3892/or_00000374.
• [2305] Frameshift Mutations of HSPA4 and MED13 in Gastric and Colorectal Cancers.Pathol Oncol Res. 2016 Oct;22(4):769-72. doi: 10.1007/s12253-016-0070-9. Epub 2016 Apr 30.
• [2306] The FOXD3/miR-214/MED19 axis suppresses tumour growth and metastasis in human colorectal cancer.Br J Cancer. 2016 Nov 22;115(11):1367-1378. doi: 10.1038/bjc.2016.362. Epub 2016 Nov 3.
• [2307] All Trans-Retinoic Acid Mediates MED28/HMG Box-Containing Protein 1 (HBP1)/-Catenin Signaling in Human Colorectal Cancer Cells.J Cell Physiol. 2016 Aug;231(8):1796-803. doi: 10.1002/jcp.25285. Epub 2015 Dec 30.
• [2308] FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma.Cancer Lett. 2017 Mar 1;388:85-95. doi: 10.1016/j.canlet.2016.11.031. Epub 2016 Dec 1.
• [2309] Myocyte enhancer factor 2D promotes colorectal cancer angiogenesis downstream of hypoxia-inducible factor 1.Cancer Lett. 2017 Aug 1;400:117-126. doi: 10.1016/j.canlet.2017.04.037. Epub 2017 May 4.
• [2310] MEGF6 Promotes the Epithelial-to-Mesenchymal Transition via the TGF/SMAD Signaling Pathway in Colorectal Cancer Metastasis.Cell Physiol Biochem. 2018;46(5):1895-1906. doi: 10.1159/000489374. Epub 2018 Apr 26.
• [2311] Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts.PLoS One. 2009 Nov 16;4(11):e7774. doi: 10.1371/journal.pone.0007774.
• [2312] The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors.PLoS One. 2013 Nov 7;8(11):e79898. doi: 10.1371/journal.pone.0079898. eCollection 2013.
• [2313] Frameshift Mutations in Repeat Sequences of ANK3, HACD4, TCP10L, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 Genes in Colon Cancers.Pathol Oncol Res. 2018 Jul;24(3):617-622. doi: 10.1007/s12253-017-0287-2. Epub 2017 Aug 12.
• [2314] Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway.J Exp Clin Cancer Res. 2019 Sep 6;38(1):393. doi: 10.1186/s13046-019-1408-4.
• [2315] Replication stress links structural and numerical cancer chromosomal instability.Nature. 2013 Feb 28;494(7438):492-496. doi: 10.1038/nature11935.
• [2316] MFAP3L activation promotes colorectal cancer cell invasion and metastasis.Biochim Biophys Acta. 2014 Sep;1842(9):1423-32. doi: 10.1016/j.bbadis.2014.04.006. Epub 2014 Apr 13.
• [2317] MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway.Oncotarget. 2016 Nov 29;7(48):78726-78735. doi: 10.18632/oncotarget.12807.
• [2318] Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer.PLoS Genet. 2016 Oct 10;12(10):e1006296. doi: 10.1371/journal.pgen.1006296. eCollection 2016 Oct.
• [2319] MicroRNA-222 influences migration and invasion through MIA3 in colorectal cancer.Cancer Cell Int. 2017 Aug 29;17:78. doi: 10.1186/s12935-017-0447-1. eCollection 2017.
• [2320] MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance.Theranostics. 2018 Oct 22;8(19):5289-5306. doi: 10.7150/thno.28228. eCollection 2018.
• [2321] C35 is overexpressed in colorectal cancer and is associated tumor invasion and metastasis.Biosci Trends. 2015 Apr;9(2):117-21. doi: 10.5582/bst.2015.01057.
• [2322] MIER3 suppresses colorectal cancer progression by down-regulating Sp1, inhibiting epithelial-mesenchymal transition.Sci Rep. 2017 Sep 8;7(1):11000. doi: 10.1038/s41598-017-11374-y.
• [2323] MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.J Pathol. 2017 Jan;241(1):67-79. doi: 10.1002/path.4823. Epub 2016 Nov 24.
• [2324] Inflammatory Molecule, PSGL-1, Deficiency Activates Macrophages to Promote Colorectal Cancer Growth through NFB Signaling.Mol Cancer Res. 2017 Apr;15(4):467-477. doi: 10.1158/1541-7786.MCR-16-0309. Epub 2017 Jan 20.
• [2325] AF1q Mediates Tumor Progression in Colorectal Cancer by Regulating AKT Signaling.Int J Mol Sci. 2017 May 5;18(5):987. doi: 10.3390/ijms18050987.
• [2326] High expression of MMP19 is associated with poor prognosis in patients with colorectal cancer.BMC Cancer. 2019 May 14;19(1):448. doi: 10.1186/s12885-019-5673-6.
• [2327] High expression of meningioma 1 is correlated with reduced survival rates in colorectal cancer patients.Acta Histochem. 2019 Jul;121(5):628-637. doi: 10.1016/j.acthis.2019.05.006. Epub 2019 May 24.
• [2328] MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance.J Exp Clin Cancer Res. 2018 Nov 26;37(1):284. doi: 10.1186/s13046-018-0956-3.
• [2329] MNX1 promotes cell proliferation and activates Wnt/-catenin signaling in colorectal cancer.Cell Biol Int. 2019 Apr;43(4):402-408. doi: 10.1002/cbin.11096. Epub 2019 Feb 19.
• [2330] Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer.Int J Oncol. 2007 Aug;31(2):333-8.
• [2331] MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1.Cancer Sci. 2019 Jan;110(1):135-146. doi: 10.1111/cas.13863. Epub 2018 Dec 21.
• [2332] Prognostic impact of changes in base excision repair machinery in sporadic colorectal cancer.Pathol Res Pract. 2018 Jan;214(1):64-71. doi: 10.1016/j.prp.2017.11.012. Epub 2017 Nov 15.
• [2333] Lentivirus-mediated knockdown of M-phase phosphoprotein 8 inhibits proliferation of colon cancer cells.Biotechnol Appl Biochem. 2017 Nov;64(6):911-917. doi: 10.1002/bab.1504. Epub 2017 Sep 7.
• [2334] MRN (MRE11-RAD50-NBS1) Complex in Human Cancer and Prognostic Implications in Colorectal Cancer.Int J Mol Sci. 2019 Feb 14;20(4):816. doi: 10.3390/ijms20040816.
• [2335] MRG-binding protein contributes to colorectal cancer development.Cancer Sci. 2011 Aug;102(8):1486-92. doi: 10.1111/j.1349-7006.2011.01971.x. Epub 2011 Jun 9.
• [2336] HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion.Sci Rep. 2015 Mar 24;5:9429. doi: 10.1038/srep09429.
• [2337] The miR-608 rs4919510 polymorphism may modify cancer susceptibility based on type.Tumour Biol. 2017 Jun;39(6):1010428317703819. doi: 10.1177/1010428317703819.
• [2338] Immature Colon Carcinoma Transcript-1 (ICT1) Expression Correlates with Unfavorable Prognosis and Survival in Patients with Colorectal Cancer.Ann Surg Oncol. 2016 Nov;23(12):3924-3933. doi: 10.1245/s10434-016-5305-1. Epub 2016 Jul 13.
• [2339] Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium.Sci Rep. 2019 Feb 7;9(1):1629. doi: 10.1038/s41598-018-38310-y.
• [2340] Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells.Oncol Rep. 2017 May;37(5):2633-2651. doi: 10.3892/or.2017.5547. Epub 2017 Apr 3.
• [2341] RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3.Lab Invest. 2018 Aug;98(8):989-998. doi: 10.1038/s41374-018-0071-2. Epub 2018 Jun 8.
• [2342] Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.Cancer. 2015 Oct 15;121(20):3684-91. doi: 10.1002/cncr.29465. Epub 2015 Jun 24.
• [2343] MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer.Transl Oncol. 2019 Nov;12(11):1461-1467. doi: 10.1016/j.tranon.2019.07.011. Epub 2019 Aug 14.
• [2344] Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.J Natl Cancer Inst. 2019 Jun 1;111(6):584-596. doi: 10.1093/jnci/djy160.
• [2345] Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466.
• [2346] Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis.Oncogene. 2017 Jun 1;36(22):3104-3118. doi: 10.1038/onc.2016.460. Epub 2017 Jan 9.
• [2347] MTUS1 and its targeting miRNAs in colorectal carcinoma: significant associations.Tumour Biol. 2016 May;37(5):6637-45. doi: 10.1007/s13277-015-4550-4. Epub 2015 Dec 7.
• [2348] Mucin Expression in Colorectal Cancer (CRC): Systematic Review and Meta-Analysis.J Clin Gastroenterol. 2019 Jul;53(6):434-440. doi: 10.1097/MCG.0000000000001050.
• [2349] Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma.Mod Pathol. 2015 Feb;28(2):268-78. doi: 10.1038/modpathol.2014.96. Epub 2014 Aug 1.
• [2350] Elevated Microsatellite Alterations at Selected Tetranucleotide Repeats (EMAST) and Microsatellite Instability in Patients with Colorectal Cancer and Its Clinical Features.Curr Mol Med. 2016;16(9):829-839. doi: 10.2174/1566524016666161124103020.
• [2351] Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer.Acta Biochim Biophys Sin (Shanghai). 2016 May;48(5):430-6. doi: 10.1093/abbs/gmw020. Epub 2016 Apr 3.
• [2352] MYH9 Promotes Growth and Metastasis via Activation of MAPK/AKT Signaling in Colorectal Cancer.J Cancer. 2019 Jan 29;10(4):874-884. doi: 10.7150/jca.27635. eCollection 2019.
• [2353] Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.Nat Genet. 2010 Nov;42(11):973-7. doi: 10.1038/ng.670. Epub 2010 Oct 24.
• [2354] Protease activated receptor 2 mediates tryptase-induced cell migration through MYO10 in colorectal cancer.Am J Cancer Res. 2019 Sep 1;9(9):1995-2006. eCollection 2019.
• [2355] Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence.Br J Cancer. 2017 Nov 21;117(11):1689-1701. doi: 10.1038/bjc.2017.352. Epub 2017 Oct 12.
• [2356] Long non-coding RNA SOX21-AS1 sponges miR-145 to promote the tumorigenesis of colorectal cancer by targeting MYO6.Biomed Pharmacother. 2017 Dec;96:953-959. doi: 10.1016/j.biopha.2017.11.145. Epub 2017 Dec 6.
• [2357] Correction: Expression of MYSM1 is associated with tumor progression in colorectal cancer.PLoS One. 2017 Oct 11;12(10):e0186530. doi: 10.1371/journal.pone.0186530. eCollection 2017.
• [2358] Role of extracellular LncRNA-SNHG14/miRNA-3940-5p/NAP12 mRNA in colorectal cancer.Arch Physiol Biochem. 2021 Dec;127(6):479-485. doi: 10.1080/13813455.2019.1650070. Epub 2019 Aug 9.
• [2359] Neuron navigator 2 overexpression indicates poor prognosis of colorectal cancer and promotes invasion through the SSH1L/cofilin-1 pathway.J Exp Clin Cancer Res. 2015 Oct 9;34:117. doi: 10.1186/s13046-015-0237-3.
• [2360] AIBP and APOA-I synergistically inhibit intestinal tumor growth and metastasis by promoting cholesterol efflux.J Transl Med. 2019 May 17;17(1):161. doi: 10.1186/s12967-019-1910-7.
• [2361] Validation of Prognosis Value of Cumulative Prognostic Scores Based on Serum High-Density Lipoprotein Cholesterol and Albumin Levels in Patients with Colorectal Cancer.J Cancer. 2019 Jan 1;10(1):35-42. doi: 10.7150/jca.26637. eCollection 2019.
• [2362] Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.Int J Cancer. 2014 Mar 15;134(6):1399-407. doi: 10.1002/ijc.28457. Epub 2013 Nov 14.
• [2363] NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway.Oncotarget. 2017 Nov 14;8(64):107932-107946. doi: 10.18632/oncotarget.22429. eCollection 2017 Dec 8.
• [2364] Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort.PLoS One. 2015 Sep 4;10(9):e0136796. doi: 10.1371/journal.pone.0136796. eCollection 2015.
• [2365] Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.Oncotarget. 2017 Jul 11;8(28):46191-46203. doi: 10.18632/oncotarget.17580.
• [2366] Expression of NDRG2 in Human Colorectal Cancer and its Association with Prognosis.J Cancer. 2019 Jun 9;10(15):3373-3380. doi: 10.7150/jca.31382. eCollection 2019.
• [2367] Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4.Oncotarget. 2016 Dec 20;7(51):84938-84950. doi: 10.18632/oncotarget.12915.
• [2368] LncRNA MAFG-AS1 promotes the progression of colorectal cancer by sponging miR-147b and activation of NDUFA4.Biochem Biophys Res Commun. 2018 Nov 17;506(1):251-258. doi: 10.1016/j.bbrc.2018.10.112. Epub 2018 Oct 19.
• [2369] Overexpression of NDUFA4L2 is associated with poor prognosis in patients with colorectal cancer.ANZ J Surg. 2017 Dec;87(12):E251-E255. doi: 10.1111/ans.13617. Epub 2016 May 25.
• [2370] Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents.PLoS One. 2015 Oct 26;10(10):e0140975. doi: 10.1371/journal.pone.0140975. eCollection 2015.
• [2371] Colorectal cancer stages transcriptome analysis.PLoS One. 2017 Nov 28;12(11):e0188697. doi: 10.1371/journal.pone.0188697. eCollection 2017.
• [2372] Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion.Onco Targets Ther. 2018 Dec 5;11:8741-8750. doi: 10.2147/OTT.S186266. eCollection 2018.
• [2373] Lymphangiogenic Gene Expression Is Associated With Lymph Node Recurrence and Poor Prognosis After Partial Hepatectomy for Colorectal Liver Metastasis.Ann Surg. 2017 Nov;266(5):765-771. doi: 10.1097/SLA.0000000000002430.
• [2374] KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22122-22131. doi: 10.1073/pnas.1908353116. Epub 2019 Oct 14.
• [2375] ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.BMC Cancer. 2016 Jul 20;16:508. doi: 10.1186/s12885-016-2576-7.
• [2376] A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90.Oncogene. 2020 Feb;39(6):1347-1360. doi: 10.1038/s41388-019-1055-4. Epub 2019 Oct 22.
• [2377] New addiction to the NRF2-related factor NRF3 in cancer cells: Ubiquitin-independent proteolysis through the 20S proteasome.Cancer Sci. 2020 Jan;111(1):6-14. doi: 10.1111/cas.14244. Epub 2019 Dec 14.
• [2378] miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44.Theranostics. 2019 Oct 22;9(26):8409-8425. doi: 10.7150/thno.36605. eCollection 2019.
• [2379] NFYB-induced high expression of E2F1 contributes to oxaliplatin resistance in colorectal cancer via the enhancement of CHK1 signaling.Cancer Lett. 2018 Feb 28;415:58-72. doi: 10.1016/j.canlet.2017.11.040. Epub 2017 Dec 22.
• [2380] Variation in the Use of Resection for Colorectal Cancer Liver Metastases.Ann Surg. 2019 Nov;270(5):892-898. doi: 10.1097/SLA.0000000000003534.
• [2381] Ninjurin 2 overexpression promotes human colorectal cancer cell growth in vitro and in vivo.Aging (Albany NY). 2019 Oct 9;11(19):8526-8541. doi: 10.18632/aging.102336. Epub 2019 Oct 9.
• [2382] NIT1 suppresses tumour proliferation by activating the TGF1-Smad2/3 signalling pathway in colorectal cancer.Cell Death Dis. 2018 Feb 15;9(3):263. doi: 10.1038/s41419-018-0333-3.
• [2383] Systematic Functional Interrogation of Genes in GWAS Loci Identified ATF1 as a Key Driver in Colorectal Cancer Modulated by a Promoter-Enhancer Interaction.Am J Hum Genet. 2019 Jul 3;105(1):29-47. doi: 10.1016/j.ajhg.2019.05.004. Epub 2019 Jun 13.
• [2384] Nemolike kinase expression predicts poor survival in colorectal cancer.Mol Med Rep. 2015 Feb;11(2):1181-7. doi: 10.3892/mmr.2014.2851. Epub 2014 Nov 3.
• [2385] NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.Cell Cycle. 2017 Jul 3;16(13):1243-1251. doi: 10.1080/15384101.2017.1317414. Epub 2017 Jun 9.
• [2386] NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.Hepatology. 2019 Nov;70(5):1582-1599. doi: 10.1002/hep.30693. Epub 2019 May 23.
• [2387] Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population.Sci Rep. 2016 Apr 28;6:25194. doi: 10.1038/srep25194.
• [2388] The Long Noncoding RNA, LINC01555, Promotes Invasion and Metastasis of Colorectal Cancer by Activating the Neuropeptide, Neuromedin U.Med Sci Monit. 2019 May 30;25:4014-4024. doi: 10.12659/MSM.916508.
• [2389] Low-level miR-646 in colorectal cancer inhibits cell proliferation and migration by targeting NOB1 expression.Oncol Lett. 2017 Dec;14(6):6708-6714. doi: 10.3892/ol.2017.7032. Epub 2017 Sep 22.
• [2390] Genetic association of PLCE1, C11orf92-C11orf93, and NOC3L with colorectal cancer risk in the Han population.Tumour Biol. 2014 Mar;35(3):1813-7. doi: 10.1007/s13277-013-1242-9. Epub 2013 Oct 22.
• [2391] NOMO-1 gene is deleted in early-onset colorectal cancer.Oncotarget. 2017 Apr 11;8(15):24429-24436. doi: 10.18632/oncotarget.15478.
• [2392] Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO.Oncotarget. 2016 Jul 5;7(27):42183-42194. doi: 10.18632/oncotarget.9741.
• [2393] NOTUM Is Involved in the Progression of Colorectal Cancer.Cancer Genomics Proteomics. 2018 Nov-Dec;15(6):485-497. doi: 10.21873/cgp.20107.
• [2394] Silencing NPAS2 promotes cell growth and invasion in DLD-1 cells and correlated with poor prognosis of colorectal cancer.Biochem Biophys Res Commun. 2014 Jul 25;450(2):1058-62. doi: 10.1016/j.bbrc.2014.06.104. Epub 2014 Jun 27.
• [2395] Nuclear receptor binding protein 1 correlates with better prognosis and induces caspase-dependent intrinsic apoptosis through the JNK signalling pathway in colorectal cancer.Cell Death Dis. 2018 Apr 1;9(4):436. doi: 10.1038/s41419-018-0402-7.
• [2396] Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.JCI Insight. 2018 Apr 19;3(8):e91316. doi: 10.1172/jci.insight.91316. eCollection 2018 Apr 19.
• [2397] Up-regulated NRIP2 in colorectal cancer initiating cells modulates the Wnt pathway by targeting ROR.Mol Cancer. 2017 Jan 31;16(1):20. doi: 10.1186/s12943-017-0590-2.
• [2398] Downregulation of NSD3 (WHSC1L1) inhibits cell proliferation and migration via ERK1/2 deactivation and decreasing CAPG expression in colorectal cancer cells.Onco Targets Ther. 2019 May 21;12:3933-3943. doi: 10.2147/OTT.S191732. eCollection 2019.
• [2399] Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth.Oncotarget. 2017 Apr 11;8(15):25055-25065. doi: 10.18632/oncotarget.15918.
• [2400] Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype.Cancer Cell. 2019 Feb 11;35(2):256-266.e5. doi: 10.1016/j.ccell.2018.12.011.
• [2401] Netrin-4 overexpression suppresses primary and metastatic colorectal tumor progression.Oncol Rep. 2013 Jan;29(1):73-8. doi: 10.3892/or.2012.2104. Epub 2012 Oct 23.
• [2402] Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1.Cancer Lett. 2015 Mar 1;358(1):76-84. doi: 10.1016/j.canlet.2014.12.040. Epub 2014 Dec 18.
• [2403] Expression of family with sequence similarity 172 member A and nucleotide-binding protein 1 is associated with the poor prognosis of colorectal carcinoma.Oncol Lett. 2017 Sep;14(3):3587-3593. doi: 10.3892/ol.2017.6585. Epub 2017 Jul 15.
• [2404] NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.Cancer Sci. 2017 Jun;108(6):1169-1176. doi: 10.1111/cas.13243. Epub 2017 Jun 14.
• [2405] High NUCB2 expression level is associated with metastasis and may promote tumor progression in colorectal cancer.Oncol Lett. 2018 Jun;15(6):9188-9194. doi: 10.3892/ol.2018.8523. Epub 2018 Apr 18.
• [2406] NUDCD1 promotes metastasis through inducing EMT and inhibiting apoptosis in colorectal cancer.Am J Cancer Res. 2018 May 1;8(5):810-823. eCollection 2018.
• [2407] MutT-related proteins are novel progression and prognostic markers for colorectal cancer.Oncotarget. 2017 Nov 11;8(62):105714-105726. doi: 10.18632/oncotarget.22393. eCollection 2017 Dec 1.
• [2408] NUP153 overexpression suppresses the proliferation of colorectal cancer by negatively regulating Wnt/-catenin signaling pathway and predicts good prognosis.Cancer Biomark. 2019;24(1):61-70. doi: 10.3233/CBM-181703.
• [2409] Increased serum level of Nup88 protein is associated with the development of colorectal cancer.Med Oncol. 2012 Sep;29(3):1789-95. doi: 10.1007/s12032-011-0047-1. Epub 2011 Aug 24.
• [2410] NUSAP1 gene silencing inhibits cell proliferation, migration and invasion through inhibiting DNMT1 gene expression in human colorectal cancer.Exp Cell Res. 2018 Jun 15;367(2):216-221. doi: 10.1016/j.yexcr.2018.03.039. Epub 2018 Mar 30.
• [2411] The nutritional environment determines which and how intestinal stem cells contribute to homeostasis and tumorigenesis.Carcinogenesis. 2019 Aug 22;40(8):937-946. doi: 10.1093/carcin/bgz106.
• [2412] Cancer-testis antigen expression in digestive tract carcinomas: frequent expression in esophageal squamous cell carcinoma and its precursor lesions.Cancer Immunol Res. 2014 May;2(5):480-6. doi: 10.1158/2326-6066.CIR-13-0124. Epub 2013 Nov 11.
• [2413] Neurexophilin and PC-esterase domain family member 4 (NXPE4) and prostate androgen-regulated mucin-like protein 1 (PARM1) as prognostic biomarkers for colorectal cancer.J Cell Biochem. 2019 Oct;120(10):18041-18052. doi: 10.1002/jcb.29107. Epub 2019 Jul 11.
• [2414] Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively.PLoS One. 2018 Aug 27;13(8):e0202856. doi: 10.1371/journal.pone.0202856. eCollection 2018.
• [2415] Comprehensive Exploration to Identify Predictive DNA Markers of Np63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma.Ann Surg Oncol. 2019 Dec;26(13):4814-4825. doi: 10.1245/s10434-019-07795-w. Epub 2019 Sep 16.
• [2416] Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance.FASEB J. 2012 Jul;26(7):2764-75. doi: 10.1096/fj.12-205419. Epub 2012 Mar 21.
• [2417] The PEA-15/PED protein regulates cellular survival and invasiveness in colorectal carcinomas.Cancer Lett. 2013 Jul 28;335(2):431-40. doi: 10.1016/j.canlet.2013.02.053. Epub 2013 Mar 7.
• [2418] Incomplete cellular reprogramming of colorectal cancer cells elicits an epithelial/mesenchymal hybrid phenotype.J Biomed Sci. 2018 Jul 19;25(1):57. doi: 10.1186/s12929-018-0461-1.
• [2419] Odontogenic ameloblast-associated protein (ODAM) inhibits human colorectal cancer growth by promoting PTEN elevation and inactivating PI3K/AKT signaling.Biomed Pharmacother. 2016 Dec;84:601-607. doi: 10.1016/j.biopha.2016.09.076. Epub 2016 Sep 29.
• [2420] Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway.J Exp Clin Cancer Res. 2018 Mar 2;37(1):41. doi: 10.1186/s13046-018-0718-2.
• [2421] Olfactomedin 1 negatively regulates NF-B signalling and suppresses the growth and metastasis of colorectal cancer cells.J Pathol. 2016 Nov;240(3):352-365. doi: 10.1002/path.4784.
• [2422] HNF6 promotes tumor growth in colorectal cancer and enhances liver metastasis in mouse model.J Cell Physiol. 2019 Apr;234(4):3675-3684. doi: 10.1002/jcp.27140. Epub 2018 Sep 7.
• [2423] Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy.Clin Cancer Res. 2016 Jul 1;22(13):3298-309. doi: 10.1158/1078-0432.CCR-15-1709. Epub 2016 Feb 9.
• [2424] Wild-type p53 regulates OTOP2 transcription through DNA loop alteration of the promoter in colorectal cancer.FEBS Open Bio. 2018 Dec 20;9(1):26-34. doi: 10.1002/2211-5463.12554. eCollection 2019 Jan.
• [2425] miR-542-3p inhibits colorectal cancer cell proliferation, migration and invasion by targeting OTUB1.Am J Cancer Res. 2017 Jan 1;7(1):159-172. eCollection 2017.
• [2426] OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.Gastroenterology. 2016 Mar;150(3):659-671.e16. doi: 10.1053/j.gastro.2015.11.041. Epub 2015 Nov 24.
• [2427] Somatic Mutations and Intratumoral Heterogeneity of Cancer-Related Genes NLK, YY1 and PA2G4 in Gastric and Colorectal Cancers.Pathol Oncol Res. 2020 Oct;26(4):2813-2815. doi: 10.1007/s12253-019-00785-z. Epub 2019 Dec 11.
• [2428] TMEM206 promotes the malignancy of colorectal cancer cells by interacting with AKT and extracellular signal-regulated kinase signaling pathways.J Cell Physiol. 2019 Jul;234(7):10888-10898. doi: 10.1002/jcp.27751. Epub 2018 Nov 11.
• [2429] Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer.Oncotarget. 2017 Nov 26;8(65):108303-108315. doi: 10.18632/oncotarget.22661. eCollection 2017 Dec 12.
• [2430] Integrating proteomics and transcriptomics for the identification of potential targets in early colorectal cancer.Int J Oncol. 2019 Aug;55(2):439-450. doi: 10.3892/ijo.2019.4833. Epub 2019 Jun 27.
• [2431] Development of genistein-PEGylated silica hybrid nanomaterials with enhanced antioxidant and antiproliferative properties on HT29 human colon cancer cells.Am J Transl Res. 2018 Aug 15;10(8):2306-2323. eCollection 2018.
• [2432] SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.Front Pharmacol. 2018 Feb 2;8:956. doi: 10.3389/fphar.2017.00956. eCollection 2017.
• [2433] Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen 1(VI).Oncogene. 2016 Oct 6;35(40):5224-5236. doi: 10.1038/onc.2016.57. Epub 2016 Mar 14.
• [2434] LncRNA SLCO4A1-AS1 promotes colorectal cancer cell proliferation by enhancing autophagy via miR-508-3p/PARD3 axis.Aging (Albany NY). 2019 Jul 16;11(14):4876-4889. doi: 10.18632/aging.102081.
• [2435] PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer.Oncotarget. 2016 Apr 5;7(14):18812-24. doi: 10.18632/oncotarget.7712.
• [2436] Focal Adhesion Proteins - and -Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression.Cancer Invest. 2015;33(8):387-97. doi: 10.3109/07357907.2015.1047508. Epub 2015 Jun 26.
• [2437] PBX3 hypermethylation in peripheral blood leukocytes predicts better prognosis in colorectal cancer: A propensity score analysis.Cancer Med. 2019 Jul;8(8):4001-4011. doi: 10.1002/cam4.2321. Epub 2019 May 29.
• [2438] Poly(C)-binding protein 1 mediates drug resistance in colorectal cancer.Oncotarget. 2017 Feb 21;8(8):13312-13319. doi: 10.18632/oncotarget.14516.
• [2439] PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death.Signal Transduct Target Ther. 2019 Nov 29;4:53. doi: 10.1038/s41392-019-0087-0. eCollection 2019.
• [2440] PCDH18 is frequently inactivated by promoter methylation in colorectal cancer.Sci Rep. 2017 Jun 6;7(1):2819. doi: 10.1038/s41598-017-03133-w.
• [2441] Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers.J Pathol. 2018 Jun;245(2):222-234. doi: 10.1002/path.5073. Epub 2018 Apr 20.
• [2442] Protocadherin -A7 is down-regulated in colorectal cancer and associated with the prognosis in patients with wild-type KRAS.Hum Pathol. 2019 Jan;83:14-21. doi: 10.1016/j.humpath.2018.08.007. Epub 2018 Aug 16.
• [2443] Identification of Key Genes in Colorectal Cancer Regulated by miR-34a.Med Sci Monit. 2017 Dec 3;23:5735-5743. doi: 10.12659/msm.904937.
• [2444] Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment.Oncotarget. 2016 Apr 12;7(15):19610-9. doi: 10.18632/oncotarget.7526.
• [2445] Novel exosomal miR-46146 transfer oxaliplatin chemoresistance in colorectal cancer.Clin Transl Oncol. 2020 Jul;22(7):1105-1116. doi: 10.1007/s12094-019-02237-1. Epub 2019 Nov 14.
• [2446] Expression and functional characterization of platelet-derived growth factor receptor-like gene.World J Gastroenterol. 2010 Mar 28;16(12):1465-72. doi: 10.3748/wjg.v16.i12.1465.
• [2447] Expression of protein disulfide isomerase A3 precursor in colorectal cancer.Onco Targets Ther. 2018 Jul 19;11:4159-4166. doi: 10.2147/OTT.S154452. eCollection 2018.
• [2448] MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4.Exp Cell Res. 2018 Dec 15;373(1-2):171-179. doi: 10.1016/j.yexcr.2018.10.010. Epub 2018 Oct 19.
• [2449] A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFB and STAT3 in colorectal cancer cells.Gastroenterology. 2014 Oct;147(4):847-859.e11. doi: 10.1053/j.gastro.2014.06.006. Epub 2014 Jun 12.
• [2450] Epstein-Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study.Hum Vaccin Immunother. 2017 Jul 3;13(7):1573-1578. doi: 10.1080/21645515.2017.1302046. Epub 2017 Mar 28.
• [2451] Podoplanin expression identified in stromal fibroblasts as a favorable prognostic marker in patients with colorectal carcinoma.Oncology. 2009;77(1):53-62. doi: 10.1159/000226112. Epub 2009 Jun 25.
• [2452] Improved amplification efficiency on stool samples by addition of spermidine and its use for non-invasive detection of colorectal cancer.BMC Biotechnol. 2015 May 29;15:41. doi: 10.1186/s12896-015-0148-6.
• [2453] Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression.PLoS One. 2019 Oct 28;14(10):e0224396. doi: 10.1371/journal.pone.0224396. eCollection 2019.
• [2454] PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.Biochem Biophys Res Commun. 2013 Feb 15;431(3):460-5. doi: 10.1016/j.bbrc.2012.12.145. Epub 2013 Jan 16.
• [2455] PFDN1, an indicator for colorectal cancer prognosis, enhances tumor cell proliferation and motility through cytoskeletal reorganization.Med Oncol. 2015 Dec;32(12):264. doi: 10.1007/s12032-015-0710-z. Epub 2015 Nov 9.
• [2456] Abnormal expression of PFDN4 in colorectal cancer: a novel marker for prognosis.Ann Surg Oncol. 2010 Nov;17(11):3030-6. doi: 10.1245/s10434-010-1138-5. Epub 2010 Jun 15.
• [2457] Identification of profilin 1 as the primary target for the anti-cancer activities of Furowanin A in colorectal cancer.Pharmacol Rep. 2019 Oct;71(5):940-949. doi: 10.1016/j.pharep.2019.05.007. Epub 2019 May 30.
• [2458] Loss of profilin2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer.Int J Oncol. 2018 Sep;53(3):1118-1128. doi: 10.3892/ijo.2018.4475. Epub 2018 Jul 9.
• [2459] The ratio of thioredoxin/Keap1 protein level is a predictor of distant metastasis in colorectal cancer.Biomark Med. 2017 Dec;11(12):1103-1111. doi: 10.2217/bmm-2017-0107. Epub 2017 Oct 20.
• [2460] Low expression of B-Cell-Associated protein 31 is associated with unfavorable prognosis in human colorectal cancer.Pathol Res Pract. 2018 May;214(5):661-666. doi: 10.1016/j.prp.2018.03.023. Epub 2018 Mar 31.
• [2461] Histone Demethylase Gene PHF2 Is Mutated in Gastric and Colorectal Cancers.Pathol Oncol Res. 2017 Jul;23(3):471-476. doi: 10.1007/s12253-016-0130-1. Epub 2016 Oct 15.
• [2462] The potential role of PHF6 as an oncogene: a genotranscriptomic/proteomic meta-analysis.Tumour Biol. 2016 Apr;37(4):5317-25. doi: 10.1007/s13277-015-4250-0. Epub 2015 Nov 11.
• [2463] Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics.BMC Gastroenterol. 2018 Feb 7;18(1):26. doi: 10.1186/s12876-018-0752-8.
• [2464] Phosphorylase kinase affects colorectal cancer cell growth and represents a novel prognostic biomarker.J Cancer Res Clin Oncol. 2017 Jun;143(6):971-980. doi: 10.1007/s00432-017-2362-1. Epub 2017 Mar 8.
• [2465] Oncogenic effect of PHLDB2 is associated with epithelial-mesenchymal transition and E-cadherin regulation in colorectal cancer.Cancer Cell Int. 2019 Jul 16;19:184. doi: 10.1186/s12935-019-0903-1. eCollection 2019.
• [2466] High Expression and Clinical Significance of Elafin in Colorectal Cancer.Gastroenterol Res Pract. 2019 Jun 9;2019:4946824. doi: 10.1155/2019/4946824. eCollection 2019.
• [2467] A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients.Int J Oncol. 2012 Oct;41(4):1405-10. doi: 10.3892/ijo.2012.1567. Epub 2012 Jul 23.
• [2468] PIK3R3 promotes chemotherapeutic sensitivity of colorectal cancer through PIK3R3/NF-kB/TP pathway.Cancer Biol Ther. 2018 Mar 4;19(3):222-229. doi: 10.1080/15384047.2017.1416936. Epub 2018 Jan 25.
• [2469] Melatonin Promotes Apoptosis of Colorectal Cancer Cells via Superoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression.Anticancer Res. 2018 Jul;38(7):3951-3960. doi: 10.21873/anticanres.12681.
• [2470] Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.World J Gastroenterol. 2016 Dec 21;22(47):10325-10340. doi: 10.3748/wjg.v22.i47.10325.
• [2471] Hydrogen Sulfide-Activatable Second Near-Infrared Fluorescent Nanoassemblies for Targeted Photothermal Cancer Therapy.Nano Lett. 2018 Oct 10;18(10):6411-6416. doi: 10.1021/acs.nanolett.8b02767. Epub 2018 Sep 24.
• [2472] The association between fecal enterotoxigenic B. fragilis with colorectal cancer.BMC Cancer. 2019 Sep 5;19(1):879. doi: 10.1186/s12885-019-6115-1.
• [2473] Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells.Cells. 2019 Nov 5;8(11):1390. doi: 10.3390/cells8111390.
• [2474] Correlation of HIWI and HILI Expression with Cancer Stem Cell Markers in Colorectal Cancer.Anticancer Res. 2015 Jun;35(6):3317-24.
• [2475] A copy number variation in PKD1L2 is associated with colorectal cancer predisposition in korean population.Int J Cancer. 2017 Jan 1;140(1):86-94. doi: 10.1002/ijc.30421. Epub 2016 Oct 3.
• [2476] Germline PKHD1 mutations are protective against colorectal cancer.Hum Genet. 2011 Mar;129(3):345-9. doi: 10.1007/s00439-011-0950-8. Epub 2011 Jan 28.
• [2477] Phospholipase A2 Group III and Group X Have Opposing Associations with Prognosis in Colorectal Cancer.Anticancer Res. 2015 May;35(5):2983-90.
• [2478] Relationship between polymorphisms of the lipid metabolism-related gene PLA2G16 and risk of colorectal cancer in the Chinese population.Funct Integr Genomics. 2019 Mar;19(2):227-236. doi: 10.1007/s10142-018-0642-8. Epub 2018 Oct 20.
• [2479] Altered expression of the PLAGL1 (ZAC1/LOT1) gene in colorectal cancer: Correlations to the clinicopathological parameters.Int J Oncol. 2015 Sep;47(3):951-62. doi: 10.3892/ijo.2015.3067. Epub 2015 Jun 29.
• [2480] Cytoplasmic phospholipase A2 alpha overexpression in stromal cells is correlated with angiogenesis in human colorectal cancer.Mod Pathol. 2005 Feb;18(2):212-20. doi: 10.1038/modpathol.3800284.
• [2481] Phospholipase C1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells.Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13505-10. doi: 10.1073/pnas.1405374111. Epub 2014 Sep 2.
• [2482] GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.Carcinogenesis. 2018 May 3;39(5):652-660. doi: 10.1093/carcin/bgy026.
• [2483] Association between phospholipase C epsilon gene (PLCE1) polymorphism and colorectal cancer risk in a Chinese population.J Int Med Res. 2014 Apr;42(2):270-81. doi: 10.1177/0300060513492484. Epub 2014 Feb 4.
• [2484] Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling.J Exp Clin Cancer Res. 2019 Oct 26;38(1):426. doi: 10.1186/s13046-019-1418-2.
• [2485] PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms.Oncotarget. 2015 Nov 3;6(34):36689-99. doi: 10.18632/oncotarget.5385.
• [2486] PMEPA1 induces EMT via a non-canonical TGF- signalling in colorectal cancer.J Cell Mol Med. 2019 May;23(5):3603-3615. doi: 10.1111/jcmm.14261. Epub 2019 Mar 19.
• [2487] Human CAP10-Like Protein 46kDa Gene Promotes Malignancy in Colorectal Cancer.OMICS. 2017 May;21(5):266-274. doi: 10.1089/omi.2017.0037.
• [2488] Novel candidates in early-onset familial colorectal cancer.Fam Cancer. 2020 Jan;19(1):1-10. doi: 10.1007/s10689-019-00145-5. Epub 2019 Sep 25.
• [2489] TP53 loss creates therapeutic vulnerability incolorectal cancer.Nature. 2015 Apr 30;520(7549):697-701. doi: 10.1038/nature14418. Epub 2015 Apr 22.
• [2490] Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.Biomed Pharmacother. 2014 Sep;68(7):841-6. doi: 10.1016/j.biopha.2014.08.014. Epub 2014 Aug 20.
• [2491] POTEE drives colorectal cancer development via regulating SPHK1/p65 signaling.Cell Death Dis. 2019 Nov 13;10(11):863. doi: 10.1038/s41419-019-2046-7.
• [2492] PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways.Oncotarget. 2017 Apr 24;8(35):58611-58624. doi: 10.18632/oncotarget.17381. eCollection 2017 Aug 29.
• [2493] PPARG rs3856806 C>T Polymorphism Increased the Risk of Colorectal Cancer: A Case-Control Study in Eastern Chinese Han Population.Front Oncol. 2019 Feb 19;9:63. doi: 10.3389/fonc.2019.00063. eCollection 2019.
• [2494] Genetic variations in the xenobiotic-metabolizing enzymes CYP1A1, CYP1A2, CYP2C9, CYP2C19 and susceptibility to colorectal cancer among Turkish people.Genet Test Mol Biomarkers. 2014 Apr;18(4):223-8. doi: 10.1089/gtmb.2013.0358. Epub 2014 Feb 14.
• [2495] Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma.Biomed Pharmacother. 2017 Mar;87:366-374. doi: 10.1016/j.biopha.2016.12.103. Epub 2017 Jan 6.
• [2496] Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts.Br J Cancer. 2019 May;120(10):987-995. doi: 10.1038/s41416-019-0450-5. Epub 2019 Apr 16.
• [2497] PPP1R12A Copy Number Is Associated with Clinical Outcomes of Stage III CRC Receiving Oxaliplatin-Based Chemotherapy. Mediators Inflamm. 2015;2015:417184. doi: 10.1155/2015/417184. Epub 2015 May 31.
• [2498] Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer.Mol Oncol. 2019 Dec;13(12):2646-2662. doi: 10.1002/1878-0261.12575. Epub 2019 Oct 24.
• [2499] LncRNA KCNQ1OT1 enhanced the methotrexate resistance of colorectal cancer cells by regulating miR-760/PPP1R1B via the cAMP signalling pathway.J Cell Mol Med. 2019 Jun;23(6):3808-3823. doi: 10.1111/jcmm.14071. Epub 2019 Apr 17.
• [2500] Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer.Oncotarget. 2014 Sep 30;5(18):8492-502. doi: 10.18632/oncotarget.2329.
• [2501] miR-892a regulated PPP2R2A expression and promoted cell proliferation of human colorectal cancer cells.Biomed Pharmacother. 2015 May;72:119-24. doi: 10.1016/j.biopha.2015.04.015. Epub 2015 Apr 27.
• [2502] PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential.Mol Cancer Ther. 2014 Apr;13(4):938-47. doi: 10.1158/1535-7163.MCT-13-0150. Epub 2014 Jan 21.
• [2503] PRDM14 promotes malignant phenotype and correlates with poor prognosis in colorectal cancer.Clin Transl Oncol. 2020 Jul;22(7):1126-1137. doi: 10.1007/s12094-019-02239-z. Epub 2019 Nov 18.
• [2504] Peroxiredoxin 1 promoted tumor metastasis and angiogenesis in colorectal cancer.Pathol Res Pract. 2018 May;214(5):655-660. doi: 10.1016/j.prp.2018.03.026. Epub 2018 Apr 3.
• [2505] Morphological, immunohistochemical and molecular features of inflammatory bowel disease associated colorectal carcinoma and associated mucosal lesions - Single institution experience.Pathol Res Pract. 2019 Apr;215(4):730-737. doi: 10.1016/j.prp.2019.01.010. Epub 2019 Jan 11.
• [2506] Expression of PRDX6 Correlates with Migration and Invasiveness of Colorectal Cancer Cells.Cell Physiol Biochem. 2018;51(6):2616-2630. doi: 10.1159/000495934. Epub 2018 Dec 11.
• [2507] AMPK1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.Oncogene. 2020 Jan;39(3):637-650. doi: 10.1038/s41388-019-1004-2. Epub 2019 Sep 17.
• [2508] DT-13 inhibited the proliferation of colorectal cancer via glycolytic metabolism and AMPK/mTOR signaling pathway.Phytomedicine. 2019 Feb 15;54:120-131. doi: 10.1016/j.phymed.2018.09.003. Epub 2018 Sep 14.
• [2509] Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression.Int J Biol Markers. 2020 Mar;35(1):3-9. doi: 10.1177/1724600819888512. Epub 2019 Dec 2.
• [2510] Curcumin induces apoptosis in human colorectal carcinoma (HCT-15) cells by regulating expression of Prp4 and p53.Mol Cells. 2013 Jun;35(6):526-32. doi: 10.1007/s10059-013-0038-5. Epub 2013 May 16.
• [2511] Cell-Cycle-Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis.Cancer Res. 2019 Sep 15;79(18):4650-4664. doi: 10.1158/0008-5472.CAN-18-2486. Epub 2019 Jun 28.
• [2512] PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas.Genomics. 2005 Mar;85(3):338-51. doi: 10.1016/j.ygeno.2004.11.002.
• [2513] Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer.Int J Clin Exp Pathol. 2015 Sep 1;8(9):10534-44. eCollection 2015.
• [2514] EpCAM Aptamer-Functionalized Cationic Liposome-Based Nanoparticles Loaded with miR-139-5p for Targeted Therapy in Colorectal Cancer.Mol Pharm. 2019 Nov 4;16(11):4696-4710. doi: 10.1021/acs.molpharmaceut.9b00867. Epub 2019 Oct 21.
• [2515] Silencing of Proteasome 26S Subunit ATPase 2 Regulates Colorectal Cancer Cell Proliferation, Apoptosis, and Migration.Chemotherapy. 2019;64(3):146-154. doi: 10.1159/000502224. Epub 2019 Nov 12.
• [2516] REG Controls Hippo Signaling and Reciprocal NF-B-YAP Regulation to Promote Colon Cancer.Clin Cancer Res. 2018 Apr 15;24(8):2015-2025. doi: 10.1158/1078-0432.CCR-17-2986. Epub 2018 Feb 6.
• [2517] Phosphoserine Phosphatase Is a Novel Prognostic Biomarker on Chromosome 7 in Colorectal Cancer.Anticancer Res. 2017 May;37(5):2365-2371. doi: 10.21873/anticanres.11574.
• [2518] Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer.Front Med (Lausanne). 2019 Jun 27;6:139. doi: 10.3389/fmed.2019.00139. eCollection 2019.
• [2519] PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1.J Exp Clin Cancer Res. 2019 Jul 10;38(1):301. doi: 10.1186/s13046-019-1312-y.
• [2520] Analysis of Potential Alterations Affecting SETBP1 as a Novel Contributing Mechanism to Inhibit PP2A in Colorectal Cancer Patients.World J Surg. 2018 Nov;42(11):3771-3778. doi: 10.1007/s00268-018-4684-9.
• [2521] PTPH1 immunohistochemical expression and promoter methylation in breast cancer patients from India: A retrospective study.J Cell Physiol. 2019 Feb;234(2):1071-1079. doi: 10.1002/jcp.27211. Epub 2018 Sep 6.
• [2522] Loss of PTPN4 activates STAT3 to promote the tumor growth in rectal cancer.Cancer Sci. 2019 Jul;110(7):2258-2272. doi: 10.1111/cas.14031. Epub 2019 May 23.
• [2523] Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer.Eur J Hum Genet. 2011 Mar;19(3):307-12. doi: 10.1038/ejhg.2010.187. Epub 2010 Dec 8.
• [2524] Downregulation of PTPRH (Sap-1) in colorectal tumors.Int J Oncol. 2017 Sep;51(3):841-850. doi: 10.3892/ijo.2017.4068. Epub 2017 Jul 5.
• [2525] Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.Oncogene. 2015 Sep 3;34(36):4692-701. doi: 10.1038/onc.2014.417. Epub 2014 Dec 22.
• [2526] MiR-6803-5p Promotes Cancer Cell Proliferation and Invasion via PTPRO/NF-B Axis in Colorectal Cancer.Mediators Inflamm. 2019 Nov 20;2019:8128501. doi: 10.1155/2019/8128501. eCollection 2019.
• [2527] Immunohistochemical and Western blot analysis of two protein tyrosine phosphatase receptors, R and Z1, in colorectal carcinoma, colon adenoma and normal colon tissues.Histol Histopathol. 2014 May;29(5):635-9. doi: 10.14670/HH-29.10.635. Epub 2013 Nov 18.
• [2528] Exome scale map of genetic alterations promoting metastasis in colorectal cancer.BMC Genet. 2018 Sep 19;19(1):85. doi: 10.1186/s12863-018-0673-0.
• [2529] The clinical value and biological function of PTTG1 in colorectal cancer.Biomed Pharmacother. 2017 May;89:108-115. doi: 10.1016/j.biopha.2017.01.115. Epub 2017 Feb 20.
• [2530] Increased serum pentraxin-3 level predicts poor prognosis in patients with colorectal cancer after curative surgery, a cohort study.Medicine (Baltimore). 2018 Oct;97(40):e11780. doi: 10.1097/MD.0000000000011780.
• [2531] Antisense RNA transcripts in the blood may be novel diagnostic markers for colorectal cancer.Oncol Lett. 2017 Sep;14(3):3487-3493. doi: 10.3892/ol.2017.6572. Epub 2017 Jul 15.
• [2532] Analysis of poliovirus receptor, CD155 expression in different human colorectal cancer cell lines: Implications for poliovirus virotherapy.J Cancer Res Ther. 2019 Jan-Mar;15(1):61-67. doi: 10.4103/jcrt.JCRT_13_17.
• [2533] FAK, Src and p-Paxillin expression is decreased in liver metastasis of colorectal carcinoma patients.J BUON. 2017 Sep-Oct;22(5):1097-1106.
• [2534] Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer.Cancer Biol Ther. 2007 Nov;6(11):1710-6. doi: 10.4161/cbt.6.11.4829. Epub 2007 Aug 3.
• [2535] Knockdown of PYCR1 inhibits proliferation, drug resistance and EMT in colorectal cancer cells by regulating STAT3-Mediated p38 MAPK and NF-B signalling pathway.Biochem Biophys Res Commun. 2019 Dec 3;520(2):486-491. doi: 10.1016/j.bbrc.2019.10.059. Epub 2019 Oct 10.
• [2536] Clinical Significance of Methylation and Reduced Expression of the Quaking Gene in Colorectal Cancer.Anticancer Res. 2017 Feb;37(2):489-498. doi: 10.21873/anticanres.11341.
• [2537] Overexpression of Rab11-FIP2 in colorectal cancer cells promotes tumor migration and angiogenesis through increasing secretion of PAI-1.Cancer Cell Int. 2018 Mar 9;18:35. doi: 10.1186/s12935-018-0532-0. eCollection 2018.
• [2538] Hypoxia-induced Rab11-family interacting protein4expression promotes migration and invasion of colon cancer and correlates with poor prognosis.Mol Med Rep. 2018 Mar;17(3):3797-3806. doi: 10.3892/mmr.2017.8283. Epub 2017 Dec 15.
• [2539] Circ_0000218 plays a carcinogenic role in colorectal cancer progression by regulating miR-139-3p/RAB1A axis.J Biochem. 2020 Jan 1;167(1):55-65. doi: 10.1093/jb/mvz078.
• [2540] Overexpression of Rab1B and MMP9 predicts poor survival and good response to chemotherapy in patients with colorectal cancer.Aging (Albany NY). 2017 Mar 18;9(3):914-931. doi: 10.18632/aging.101200.
• [2541] Colorectal cancer cells respond differentially to autophagy inhibition in vivo.Sci Rep. 2019 Aug 5;9(1):11316. doi: 10.1038/s41598-019-47659-7.
• [2542] Rab23 contributes to the progression of colorectal cancer via protein kinase B and extracellular signal-regulated kinase signaling pathways.Oncol Lett. 2019 Aug;18(2):1793-1799. doi: 10.3892/ol.2019.10491. Epub 2019 Jun 18.
• [2543] Upregulation of miR-582-5p inhibits cell proliferation, cell cycle progression and invasion by targeting Rab27a in human colorectal carcinoma.Cancer Gene Ther. 2015 Oct;22(10):475-80. doi: 10.1038/cgt.2015.44. Epub 2015 Sep 18.
• [2544] The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells.Oncotarget. 2018 Oct 5;9(78):34658-34669. doi: 10.18632/oncotarget.26157. eCollection 2018 Oct 5.
• [2545] Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients.Int J Clin Exp Pathol. 2015 Jun 1;8(6):6974-80. eCollection 2015.
• [2546] Neutral endopeptidase (NEP) inhibitors - thiorphan, sialorphin, and its derivatives exert anti-proliferative activity towards colorectal cancer cells in vitro. Chem Biol Interact. 2019 Jul 1;307:105-115. doi: 10.1016/j.cbi.2019.04.033. Epub 2019 May 1.
• [2547] Higher RABEX-5 mRNA predicts unfavourable survival in patients with colorectal cancer.Eur Rev Med Pharmacol Sci. 2017 May;21(10):2372-2376.
• [2548] RacGAP1 expression, increasing tumor malignant potential, as a predictive biomarker for lymph node metastasis and poor prognosis in colorectal cancer.Carcinogenesis. 2015 Mar;36(3):346-54. doi: 10.1093/carcin/bgu327. Epub 2015 Jan 7.
• [2549] Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer.Tumour Biol. 2015 Jul;36(7):5011-9. doi: 10.1007/s13277-015-3152-5. Epub 2015 Apr 27.
• [2550] Targeting RAD50 increases sensitivity to radiotherapy in colorectal cancer cells.Neoplasma. 2018;65(1):75-80. doi: 10.4149/neo_2018_170219N128.
• [2551] RAD52 gene polymorphisms are associated with risk of colorectal cancer in a Chinese Han population.Medicine (Baltimore). 2017 Dec;96(49):e8994. doi: 10.1097/MD.0000000000008994.
• [2552] Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3276-81. doi: 10.1073/pnas.0813414106. Epub 2009 Feb 13.
• [2553] Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer.Clin Epigenetics. 2018 May 23;10:69. doi: 10.1186/s13148-018-0501-4. eCollection 2018.
• [2554] Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.Cancer Med. 2013 Apr;2(2):196-207. doi: 10.1002/cam4.51. Epub 2013 Jan 29.
• [2555] 3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.PLoS One. 2015 Jul 6;10(7):e0131125. doi: 10.1371/journal.pone.0131125. eCollection 2015.
• [2556] Linking Nucleoporins, Mitosis, and Colon Cancer.Cell Chem Biol. 2016 May 19;23(5):537-539. doi: 10.1016/j.chembiol.2016.05.004.
• [2557] MicroRNA-147b Promotes Proliferation and Invasion of Human Colorectal Cancer by Targeting RAS Oncogene Family (RAP2B).Pathobiology. 2019;86(4):173-181. doi: 10.1159/000495253. Epub 2019 May 23.
• [2558] RASAL2 Plays Inconsistent Roles in Different Cancers.Front Oncol. 2019 Nov 13;9:1235. doi: 10.3389/fonc.2019.01235. eCollection 2019.
• [2559] RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-B pathway.Cancer Biol Ther. 2019;20(4):435-443. doi: 10.1080/15384047.2018.1529117. Epub 2018 Oct 25.
• [2560] Low expression of RASSF10 is associated with poor survival in patients with colorectal cancer.Hum Pathol. 2017 Apr;62:108-114. doi: 10.1016/j.humpath.2016.12.016. Epub 2016 Dec 30.
• [2561] Colorectal cancer and RASSF family--a special emphasis on RASSF1A.Int J Cancer. 2013 Jan 15;132(2):251-8. doi: 10.1002/ijc.27696. Epub 2012 Jul 14.
• [2562] MiR-496 promotes migration and epithelial-mesenchymal transition by targeting RASSF6 in colorectal cancer.J Cell Physiol. 2020 Feb;235(2):1469-1479. doi: 10.1002/jcp.29066. Epub 2019 Jul 4.
• [2563] MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8.J Pharm Pharmacol. 2018 Jul;70(7):937-951. doi: 10.1111/jphp.12913. Epub 2018 May 3.
• [2564] Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.Mol Cancer. 2013 Jan 3;12:1. doi: 10.1186/1476-4598-12-1.
• [2565] RNA binding protein RBM3 increases -catenin signaling to increase stem cell characteristics in colorectal cancer cells.Mol Carcinog. 2016 Nov;55(11):1503-1516. doi: 10.1002/mc.22404. Epub 2015 Aug 31.
• [2566] Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression.Sci Rep. 2017 Jul 5;7(1):4687. doi: 10.1038/s41598-017-04234-2.
• [2567] Regenerating gene 1B silencing inhibits colon cancer cell HCT116 proliferation and invasion.Int J Biol Markers. 2015 May 26;30(2):e217-25. doi: 10.5301/jbm.5000133.
• [2568] Reelin-Dab1 signaling system in human colorectal cancer.Mol Carcinog. 2017 Feb;56(2):712-721. doi: 10.1002/mc.22527. Epub 2016 Aug 8.
• [2569] Promoter hypermethylation inactivate tumor suppressor FAM134B and is associated with poor prognosis in colorectal cancer.Genes Chromosomes Cancer. 2018 May;57(5):240-251. doi: 10.1002/gcc.22525. Epub 2018 Jan 30.
• [2570] RFPL4A increases the G1 population and decreases sensitivity to chemotherapy in human colorectal cancer cells.J Biol Chem. 2015 Mar 6;290(10):6326-37. doi: 10.1074/jbc.M114.614859. Epub 2015 Jan 20.
• [2571] Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.Oncotarget. 2015 Aug 21;6(24):20540-54. doi: 10.18632/oncotarget.4110.
• [2572] Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells invitro.Int J Oncol. 2018 Sep;53(3):1313-1322. doi: 10.3892/ijo.2018.4458. Epub 2018 Jun 28.
• [2573] G-Protein Signaling Protein-17 (RGS17) Is Upregulated and Promotes Tumor Growth and Migration in Human Colorectal Carcinoma.Oncol Res. 2018 Jan 19;26(1):27-35. doi: 10.3727/096504017X14900515946914. Epub 2017 Mar 23.
• [2574] miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway.Int J Biochem Cell Biol. 2019 Dec;117:105641. doi: 10.1016/j.biocel.2019.105641. Epub 2019 Nov 3.
• [2575] Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression.Oncol Rep. 2018 Aug;40(2):909-915. doi: 10.3892/or.2018.6489. Epub 2018 Jun 14.
• [2576] Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway.J Cell Physiol. 2020 Jan;235(1):442-453. doi: 10.1002/jcp.28984. Epub 2019 Jul 22.
• [2577] Biological Characteristics and Clinical Significance of ITGB1 and RHOC in Patients With Recurrent Colorectal Cancer.Anticancer Res. 2019 Sep;39(9):4853-4864. doi: 10.21873/anticanres.13671.
• [2578] 5-Fluorouracil as a Tumor-Treating Field-Sensitizer in Colon Cancer Therapy.Cancers (Basel). 2019 Dec 12;11(12):1999. doi: 10.3390/cancers11121999.
• [2579] RNA editing in RHOQ promotes invasion potential in colorectal cancer.J Exp Med. 2014 Apr 7;211(4):613-21. doi: 10.1084/jem.20132209. Epub 2014 Mar 24.
• [2580] The E3 Ligase RING1 Targets p53 for Degradation and Promotes Cancer Cell Proliferation and Survival.Cancer Res. 2018 Jan 15;78(2):359-371. doi: 10.1158/0008-5472.CAN-17-1805. Epub 2017 Nov 29.
• [2581] Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk.PLoS One. 2017 Mar 6;12(3):e0172247. doi: 10.1371/journal.pone.0172247. eCollection 2017.
• [2582] Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.Ann Surg Oncol. 2017 Mar;24(3):841-849. doi: 10.1245/s10434-016-5395-9. Epub 2016 Jul 29.
• [2583] Mina53 nuclear localization is an important indicator of prognosis in patients with colorectal cancer after adjuvant chemotherapy.Oncol Rep. 2018 Jul;40(1):101-110. doi: 10.3892/or.2018.6407. Epub 2018 Apr 30.
• [2584] Verbascoside Attenuates Rac-1 and HIF-1 Signaling Cascade in Colorectal Cancer Cells.Anticancer Agents Med Chem. 2018;18(15):2149-2155. doi: 10.2174/1871520618666180611112125.
• [2585] DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression.Oncology. 2017;92(2):115-124. doi: 10.1159/000452281. Epub 2016 Dec 17.
• [2586] The E3 ubiquitin ligase RNF146 promotes colorectal cancer by activating the Wnt/-catenin pathway via ubiquitination of Axin1.Biochem Biophys Res Commun. 2018 Sep 5;503(2):991-997. doi: 10.1016/j.bbrc.2018.06.107. Epub 2018 Jun 25.
• [2587] Ring finger protein 152 inhibits colorectal cancer cell growth and is a novel prognostic biomarker.Am J Transl Res. 2018 Nov 15;10(11):3701-3712. eCollection 2018.
• [2588] Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells.Chin J Cancer. 2017 Jul 31;36(1):63. doi: 10.1186/s40880-017-0228-1.
• [2589] RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer.Cell Rep. 2016 Feb 16;14(6):1462-1476. doi: 10.1016/j.celrep.2016.01.020. Epub 2016 Feb 4.
• [2590] RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy.Oncotarget. 2016 Aug 9;7(32):51174-51183. doi: 10.18632/oncotarget.9433.
• [2591] Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper.Biochem Biophys Res Commun. 2001 Apr 13;282(4):1038-44. doi: 10.1006/bbrc.2001.4671.
• [2592] Frameshift mutations of axon guidance genes ROBO1 and ROBO2 in gastric and colorectal cancers with microsatellite instability.Pathology. 2013 Dec;45(7):645-50. doi: 10.1097/PAT.0000000000000007.
• [2593] Reactive oxygen species modulator-1 (Romo1) predicts unfavorable prognosis in colorectal cancer patients.PLoS One. 2017 May 4;12(5):e0176834. doi: 10.1371/journal.pone.0176834. eCollection 2017.
• [2594] Genetic variants in RPA1 associated with the response to oxaliplatin-based chemotherapy in colorectal cancer.J Gastroenterol. 2019 Nov;54(11):939-949. doi: 10.1007/s00535-019-01571-z. Epub 2019 Mar 28.
• [2595] Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression.Oncogene. 2019 Aug;38(32):6017-6034. doi: 10.1038/s41388-019-0857-8. Epub 2019 Jul 12.
• [2596] Growth inhibitory effect of adenovirus-mediated tissue-targeted expression of ribosomal protein L23 on human colorectal carcinoma cells.Oncol Rep. 2015 Aug;34(2):763-70. doi: 10.3892/or.2015.4026. Epub 2015 Jun 4.
• [2597] The HIP gene encoding a heparin/heparan sulfate interacting protein is mutated in metastatic human colorectal cancer.Int J Mol Med. 2003 Apr;11(4):473-7.
• [2598] Knockdown of RPL9 expression inhibits colorectal carcinoma growth via the inactivation of Id-1/NF-B signaling axis.Int J Oncol. 2016 Nov;49(5):1953-1962. doi: 10.3892/ijo.2016.3688. Epub 2016 Sep 13.
• [2599] MicroRNA-128 targeting RPN2 inhibits cell proliferation and migration through the Akt-p53-cyclin pathway in colorectal cancer cells.Oncol Lett. 2018 Dec;16(6):6940-6949. doi: 10.3892/ol.2018.9506. Epub 2018 Sep 26.
• [2600] Three functional variants were identified to affect RPS24 expression and significantly associated with risk of colorectal cancer.Arch Toxicol. 2020 Jan;94(1):295-303. doi: 10.1007/s00204-019-02600-9. Epub 2019 Oct 23.
• [2601] Ribosomal protein S27-like in colorectal cancer: a candidate for predicting prognoses.PLoS One. 2013 Jun 24;8(6):e67043. doi: 10.1371/journal.pone.0067043. Print 2013.
• [2602] Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.Neoplasia. 2014 Oct 23;16(10):845-60. doi: 10.1016/j.neo.2014.08.011. eCollection 2014 Oct.
• [2603] RPS7 inhibits colorectal cancer growth via decreasing HIF-1-mediated glycolysis.Oncotarget. 2016 Feb 2;7(5):5800-14. doi: 10.18632/oncotarget.6807.
• [2604] miR-496, miR-1185, miR-654, miR-3183 and miR-495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway.Oncol Lett. 2019 Aug;18(2):1657-1668. doi: 10.3892/ol.2019.10508. Epub 2019 Jun 21.
• [2605] RRBP1 overexpression is associated with progression and prognosis in endometrial endometrioid adenocarcinoma.Diagn Pathol. 2019 Jan 26;14(1):7. doi: 10.1186/s13000-019-0784-6.
• [2606] miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation.Oncol Lett. 2018 May;15(5):8107-8117. doi: 10.3892/ol.2018.8295. Epub 2018 Mar 19.
• [2607] RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.Oncotarget. 2017 Sep 15;8(47):82968-82980. doi: 10.18632/oncotarget.20897. eCollection 2017 Oct 10.
• [2608] Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.Int J Cancer. 2014 Aug 15;135(4):948-55. doi: 10.1002/ijc.28733. Epub 2014 Jan 29.
• [2609] Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.Mol Med Rep. 2016 Apr;13(4):3514-20. doi: 10.3892/mmr.2016.4951. Epub 2016 Mar 1.
• [2610] Rufy3 promotes metastasis through epithelial-mesenchymal transition in colorectal cancer.Cancer Lett. 2017 Apr 1;390:30-38. doi: 10.1016/j.canlet.2017.01.001. Epub 2017 Jan 13.
• [2611] Runt-related Transcription Factor 1 (RUNX1T1) Suppresses Colorectal Cancer Cells Through Regulation of Cell Proliferation and Chemotherapeutic Drug Resistance.Anticancer Res. 2016 Oct;36(10):5257-5263. doi: 10.21873/anticanres.11096.
• [2612] Functional polymorphism in the MicroRNA-367 binding site as a prognostic factor for colonic cancer.Anticancer Res. 2013 Feb;33(2):513-9.
• [2613] Different expression of calgizzarin (S100A11) in normal colonic epithelium, adenoma and colorectal carcinoma.Int J Oncol. 2006 Jan;28(1):195-200.
• [2614] S100A16 is a prognostic marker for colorectal cancer.J Surg Oncol. 2018 Feb;117(2):275-283. doi: 10.1002/jso.24822. Epub 2017 Sep 6.
• [2615] Knockdown of Sal-like 4 expression by siRNA induces apoptosis in colorectal cancer.J Cell Biochem. 2019 Jul;120(7):11531-11538. doi: 10.1002/jcb.28433. Epub 2019 Feb 16.
• [2616] Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, -catenin and EZH2.Carcinogenesis. 2014 Jun;35(6):1389-98. doi: 10.1093/carcin/bgu057. Epub 2014 Mar 6.
• [2617] Targeted Quantitative Proteomic Approach for Probing Altered Protein Expression of Small GTPases Associated with Colorectal Cancer Metastasis.Anal Chem. 2019 May 7;91(9):6233-6241. doi: 10.1021/acs.analchem.9b00938. Epub 2019 Apr 12.
• [2618] SASS6 overexpression is associated with mitotic chromosomal abnormalities and a poor prognosis in patients with colorectal cancer.Oncol Rep. 2015 Aug;34(2):727-38. doi: 10.3892/or.2015.4014. Epub 2015 May 28.
• [2619] Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer.Epigenetics. 2013 Jul;8(7):748-55. doi: 10.4161/epi.25178. Epub 2013 Jun 17.
• [2620] Colitis-associated colorectal adenocarcinomas are frequently associated with non-intestinal mucin profiles and loss of SATB2 expression.Mod Pathol. 2019 Jun;32(6):884-892. doi: 10.1038/s41379-018-0198-0. Epub 2019 Feb 1.
• [2621] Dpy-19 like 3-mediated C-mannosylation and expression levels of RPE-spondin in human tumor cell lines.Oncol Lett. 2017 Aug;14(2):2537-2544. doi: 10.3892/ol.2017.6465. Epub 2017 Jun 22.
• [2622] Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk.PLoS One. 2014 Feb 24;9(2):e89736. doi: 10.1371/journal.pone.0089736. eCollection 2014.
• [2623] SCGB2A1 is a novel prognostic marker for colorectal cancer associated with chemoresistance and radioresistance.Int J Oncol. 2014 May;44(5):1521-8. doi: 10.3892/ijo.2014.2316. Epub 2014 Feb 28.
• [2624] Aberrant Scinderin Expression Correlates With Liver Metastasis and Poor Prognosis in Colorectal Cancer.Front Pharmacol. 2019 Oct 31;10:1183. doi: 10.3389/fphar.2019.01183. eCollection 2019.
• [2625] Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient.Oncotarget. 2017 Jul 24;8(33):55353-55360. doi: 10.18632/oncotarget.19512. eCollection 2017 Aug 15.
• [2626] Reduced succinate dehydrogenase B expression is associated with growth and de-differentiation of colorectal cancer cells.Tumour Biol. 2013 Aug;34(4):2337-47. doi: 10.1007/s13277-013-0781-4. Epub 2013 May 5.
• [2627] Genetic variations in genes of metabolic enzymes predict postoperational prognosis of patients with colorectal cancer.Mol Cancer. 2015 Sep 17;14:171. doi: 10.1186/s12943-015-0442-x.
• [2628] Clinicopathological significance of SPC18 in colorectal cancer: SPC18 participates in tumor progression.Cancer Sci. 2017 Jan;108(1):143-150. doi: 10.1111/cas.13121.
• [2629] MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression.BMC Cancer. 2016 Aug 5;16:605. doi: 10.1186/s12885-016-2628-z.
• [2630] OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages.Clin Proteomics. 2017 Mar 24;14:9. doi: 10.1186/s12014-017-9143-3. eCollection 2017.
• [2631] Selenium-binding protein 1 is associated with the degree of colorectal cancer differentiation and is regulated by histone modification.Oncol Rep. 2014 Jun;31(6):2506-14. doi: 10.3892/or.2014.3141. Epub 2014 Apr 16.
• [2632] The influence of selenium and selenoprotein gene variants on colorectal cancer risk.Mutagenesis. 2012 Mar;27(2):177-86. doi: 10.1093/mutage/ger058.
• [2633] Decreased expression of semaphorin 3D is associated with genesis and development in colorectal cancer.World J Surg Oncol. 2017 Mar 20;15(1):67. doi: 10.1186/s12957-017-1128-1.
• [2634] MiR-4282 suppresses proliferation and mobility of human colorectal carcinoma cells by targeting semaphorin 3E.Panminerva Med. 2016 Sep;58(3):197-205. Epub 2016 Apr 27.
• [2635] SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis.J Pathol. 2015 Aug;236(4):467-78. doi: 10.1002/path.4541. Epub 2015 May 22.
• [2636] Expression of Serpin B9 as a Prognostic Factor of Colorectal Cancer.Anticancer Res. 2019 Nov;39(11):6063-6066. doi: 10.21873/anticanres.13813.
• [2637] Lymphovascular and perineural invasion are associated with poor prognostic features and outcomes in colorectal cancer: A retrospective cohort study.Int J Surg. 2017 Jan;37:42-49. doi: 10.1016/j.ijsu.2016.08.528. Epub 2016 Sep 4.
• [2638] SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer.Cancer Sci. 2016 May;107(5):619-28. doi: 10.1111/cas.12909. Epub 2016 Mar 28.
• [2639] The interaction of Hemin and Sestrin2 modulates oxidative stress and colon tumor growth. Toxicol Appl Pharmacol. 2019 Jul 1;374:77-85.
• [2640] SET nuclear proto-oncogene gene expression is associated with microsatellite instability in human colorectal cancer identified by co-expression analysis.Dig Liver Dis. 2020 Mar;52(3):339-346. doi: 10.1016/j.dld.2019.07.020. Epub 2019 Sep 6.
• [2641] Histone methyltransferase SETDB1 promotes colorectal cancer proliferation through the STAT1-CCND1/CDK6 axis.Carcinogenesis. 2020 Jul 10;41(5):678-688. doi: 10.1093/carcin/bgz131.
• [2642] MicroRNA-1296 Facilitates Proliferation, Migration And Invasion Of Colorectal Cancer Cells By Targeting SFPQ.J Cancer. 2018 Jun 6;9(13):2317-2326. doi: 10.7150/jca.25427. eCollection 2018.
• [2643] Hypermethylated Promoters of Secreted Frizzled-Related Protein Genes are Associated with Colorectal Cancer.Pathol Oncol Res. 2019 Apr;25(2):567-575. doi: 10.1007/s12253-018-0505-6. Epub 2018 Oct 27.
• [2644] SFRP4 was overexpressed in colorectal carcinoma.J Cancer Res Clin Oncol. 2010 Mar;136(3):395-401. doi: 10.1007/s00432-009-0669-2.
• [2645] Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations. Ann Surg Oncol. 2011 Aug;18(8):2338-47.
• [2646] Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer.FASEB J. 2017 Sep;31(9):3816-3830. doi: 10.1096/fj.201601225RR. Epub 2017 May 18.
• [2647] Hsa_circ_0136666 promotes the proliferation and invasion of colorectal cancer through miR-136/SH2B1 axis.J Cell Physiol. 2019 May;234(5):7247-7256. doi: 10.1002/jcp.27482. Epub 2018 Oct 28.
• [2648] Circulating sex hormone levels and colorectal cancer risk in Japanese postmenopausal women: The JPHC nested case-control study.Int J Cancer. 2019 Sep 1;145(5):1238-1244. doi: 10.1002/ijc.32431. Epub 2019 Jun 11.
• [2649] DNA Hypermethylation of SHISA3 in Colorectal Cancer: An Independent Predictor of Poor Prognosis.Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1481-9. doi: 10.1245/s10434-015-4593-1. Epub 2015 May 13.
• [2650] Stabilization of Sur8 via PKC/ degradation promotes transformation and migration of colorectal cancer cells.Oncotarget. 2017 Dec 14;8(70):115596-115608. doi: 10.18632/oncotarget.23313. eCollection 2017 Dec 29.
• [2651] Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells.Front Immunol. 2018 Sep 20;9:2138. doi: 10.3389/fimmu.2018.02138. eCollection 2018.
• [2652] Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.J Clin Invest. 2018 Nov 1;128(11):4912-4923. doi: 10.1172/JCI120612. Epub 2018 Sep 24.
• [2653] Expression of signal-induced proliferation-associated gene 1 (SIPA1), a RapGTPase-activating protein, is increased in colorectal cancer and has diverse effects on functions of colorectal cancer cells.Cancer Genomics Proteomics. 2012 Sep-Oct;9(5):321-7.
• [2654] Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells.Oncol Lett. 2018 Aug;16(2):1675-1681. doi: 10.3892/ol.2018.8850. Epub 2018 May 31.
• [2655] Sirtuin 7 promotes colorectal carcinoma proliferation and invasion through the inhibition of E-cadherin.Exp Ther Med. 2018 Mar;15(3):2333-2342. doi: 10.3892/etm.2017.5673. Epub 2017 Dec 22.
• [2656] MicroRNA-362 Inhibits Cell Proliferation and Invasion by Directly Targeting SIX1 in Colorectal Cancer.Yonsei Med J. 2019 May;60(5):414-422. doi: 10.3349/ymj.2019.60.5.414.
• [2657] The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer.Theranostics. 2017 Feb 27;7(5):1114-1132. doi: 10.7150/thno.18175. eCollection 2017.
• [2658] SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. Cancer Res. 2006 Feb 15;66(4):2279-86. doi: 10.1158/0008-5472.CAN-05-2057.
• [2659] Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer.Oncotarget. 2015 Sep 22;6(28):25368-80. doi: 10.18632/oncotarget.4681.
• [2660] Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin.Oncotarget. 2017 Apr 4;8(14):22759-22771. doi: 10.18632/oncotarget.15191.
• [2661] Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer.Epigenomics. 2017 Jun;9(6):849-862. doi: 10.2217/epi-2017-0019. Epub 2017 Apr 13.
• [2662] SUV39H2 promotes colorectal cancer proliferation and metastasis via tri-methylation of the SLIT1 promoter.Cancer Lett. 2018 May 28;422:56-69. doi: 10.1016/j.canlet.2018.02.023. Epub 2018 Feb 16.
• [2663] MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.Oncotarget. 2016 Aug 16;7(33):53443-53458. doi: 10.18632/oncotarget.10803.
• [2664] Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development.J Exp Clin Cancer Res. 2019 Mar 1;38(1):108. doi: 10.1186/s13046-019-1116-0.
• [2665] Structural maintenance of chromosomes 4 is a predictor of survival and a novel therapeutic target in colorectal cancer.Asian Pac J Cancer Prev. 2014;15(21):9459-65. doi: 10.7314/apjcp.2014.15.21.9459.
• [2666] MicroRNA-125a inhibits tumorigenesis by targeting Smurf1 in colorectal carcinoma.FEBS Open Bio. 2019 Jul;9(7):1305-1314. doi: 10.1002/2211-5463.12680. Epub 2019 Jun 17.
• [2667] Claudin-7 downregulation induces metastasis and invasion in colorectal cancer via the promotion of epithelial-mesenchymal transition.Biochem Biophys Res Commun. 2019 Jan 15;508(3):797-804. doi: 10.1016/j.bbrc.2018.10.049. Epub 2018 Dec 6.
• [2668] SNAIL- and SLUG-induced side population phenotype of HCT116 human colorectal cancer cells and its regulation by BET inhibitors.Biochem Biophys Res Commun. 2020 Jan 1;521(1):152-157. doi: 10.1016/j.bbrc.2019.10.094. Epub 2019 Oct 22.
• [2669] An oncogenic gene, SNRPA1, regulates PIK3R1, VEGFC, MKI67, CDK1 and other genes in colorectal cancer.Biomed Pharmacother. 2019 Sep;117:109076. doi: 10.1016/j.biopha.2019.109076. Epub 2019 Jun 14.
• [2670] Down-regulation of SNX1 predicts poor prognosis and contributes to drug resistance in colorectal cancer.Tumour Biol. 2016 May;37(5):6619-25. doi: 10.1007/s13277-015-3814-3. Epub 2015 Dec 7.
• [2671] SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial-to-mesenchymal transition via the -catenin pathway.Oncol Lett. 2019 Nov;18(5):5332-5340. doi: 10.3892/ol.2019.10860. Epub 2019 Sep 12.
• [2672] Overview of the oncogenic signaling pathways in colorectal cancer: Mechanistic insights.Semin Cancer Biol. 2019 Oct;58:65-79. doi: 10.1016/j.semcancer.2019.01.001. Epub 2019 Jan 8.
• [2673] Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer.Br J Cancer. 2014 Aug 12;111(4):726-35. doi: 10.1038/bjc.2014.377. Epub 2014 Jul 15.
• [2674] NEDD9 Inhibition by miR-25-5p Activation Is Critically Involved in Co-Treatment of Melatonin- and Pterostilbene-Induced Apoptosis in Colorectal Cancer Cells.Cancers (Basel). 2019 Oct 29;11(11):1684. doi: 10.3390/cancers11111684.
• [2675] Effects of SOX15 on the colorectal cancer cells via downregulation of the Wnt/-catenin signaling pathway.Future Oncol. 2018 Aug;14(19):1921-1932. doi: 10.2217/fon-2017-0688. Epub 2018 Jul 18.
• [2676] SOX17 antagonizes WNT/-catenin signaling pathway in hepatocellular carcinoma.Epigenetics. 2010 Nov-Dec;5(8):743-9. doi: 10.4161/epi.5.8.13104. Epub 2010 Nov 22.
• [2677] Upregulation of SOX18 in colorectal cancer cells promotes proliferation and correlates with colorectal cancer risk.Onco Targets Ther. 2018 Nov 29;11:8481-8490. doi: 10.2147/OTT.S178916. eCollection 2018.
• [2678] miR-140-5p inhibits cell proliferation and invasion in colorectal carcinoma by targeting SOX4.Oncol Lett. 2019 Feb;17(2):2215-2220. doi: 10.3892/ol.2018.9834. Epub 2018 Dec 14.
• [2679] TGF-1 mediates the effects of aspirin on colonic tumor cell proliferation and apoptosis.Oncol Lett. 2018 Apr;15(4):5903-5909. doi: 10.3892/ol.2018.8047. Epub 2018 Feb 14.
• [2680] Over-expression of SOX8 predicts poor prognosis in colorectal cancer: A retrospective study.Medicine (Baltimore). 2019 Jul;98(27):e16237. doi: 10.1097/MD.0000000000016237.
• [2681] Detection of SPG20 gene promoter-methylated DNA, as a novel epigenetic biomarker, in plasma for colorectal cancer diagnosis using the MethyLight method.Oncol Lett. 2017 May;13(5):3277-3284. doi: 10.3892/ol.2017.5815. Epub 2017 Mar 7.
• [2682] High Spy1 expression predicts poor prognosis in colorectal cancer.Cancer Manag Res. 2018 Aug 16;10:2757-2765. doi: 10.2147/CMAR.S169329. eCollection 2018.
• [2683] Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.PLoS One. 2012;7(4):e35307. doi: 10.1371/journal.pone.0035307. Epub 2012 Apr 19.
• [2684] SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.Clin Exp Pharmacol Physiol. 2019 Sep;46(9):861-871. doi: 10.1111/1440-1681.13124. Epub 2019 Jun 30.
• [2685] The MACC1-SPON2 axis: a new biomarker and therapeutic target in colorectal cancer.Oncogene. 2017 Mar;36(11):1474-1475. doi: 10.1038/onc.2016.322. Epub 2016 Sep 26.
• [2686] Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer.BMC Cancer. 2019 Dec 18;19(1):1230. doi: 10.1186/s12885-019-6441-3.
• [2687] Lower Expression of SPRY4 Predicts a Poor Prognosis and Regulates Cell Proliferation in Colorectal Cancer.Cell Physiol Biochem. 2016;40(6):1433-1442. doi: 10.1159/000453195. Epub 2016 Dec 20.
• [2688] Phosphoproteome Characterization of Human Colorectal Cancer SW620 Cell-Derived Exosomes and New Phosphosite Discovery for C-HPP.J Proteome Res. 2016 Nov 4;15(11):4060-4072. doi: 10.1021/acs.jproteome.6b00391. Epub 2016 Aug 11.
• [2689] Sorcin Enhances Metastasis and Promotes Epithelial-to-Mesenchymal Transition of Colorectal Cancer.Cell Biochem Biophys. 2015 Jun;72(2):453-9. doi: 10.1007/s12013-014-0486-3.
• [2690] ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.Eur J Med Chem. 2019 Jan 1;161:456-467. doi: 10.1016/j.ejmech.2018.10.052. Epub 2018 Oct 23.
• [2691] Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer.Med Oncol. 2015 Apr;32(4):99. doi: 10.1007/s12032-015-0548-4. Epub 2015 Mar 4.
• [2692] Bioinformatics analysis of SRSF1-controlled gene networks in colorectal cancer.Oncol Lett. 2017 Nov;14(5):5393-5399. doi: 10.3892/ol.2017.6900. Epub 2017 Sep 6.
• [2693] BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.Nat Commun. 2014 Aug 5;5:4581. doi: 10.1038/ncomms5581.
• [2694] SSBP1 Upregulation In Colorectal Cancer Regulates Mitochondrial Mass.Cancer Manag Res. 2019 Dec 2;11:10093-10106. doi: 10.2147/CMAR.S211292. eCollection 2019.
• [2695] LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.Virchows Arch. 2018 May;472(5):727-737. doi: 10.1007/s00428-018-2298-0. Epub 2018 Jan 19.
• [2696] miR-194 Inhibits the Proliferation of SW620 Colon Cancer Stem Cells Through Downregulation of SSH2 Expression.Cancer Manag Res. 2019 Dec 4;11:10229-10238. doi: 10.2147/CMAR.S221150. eCollection 2019.
• [2697] SSH3 facilitates colorectal cancer cell invasion and metastasis by affecting signaling cascades involving LIMK1/Rac1.Am J Cancer Res. 2019 May 1;9(5):1061-1073. eCollection 2019.
• [2698] Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer.Cancer Immunol Immunother. 2007 Jun;56(6):839-47. doi: 10.1007/s00262-006-0228-5. Epub 2006 Sep 8.
• [2699] ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines.J Zhejiang Univ Sci B. 2012 Nov;13(11):884-93. doi: 10.1631/jzus.B1200037.
• [2700] The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via JAK2/STAT3 cascade.J Exp Clin Cancer Res. 2019 Nov 6;38(1):455. doi: 10.1186/s13046-019-1468-5.
• [2701] ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.Oncotarget. 2017 Nov 8;8(68):112550-112564. doi: 10.18632/oncotarget.22545. eCollection 2017 Dec 22.
• [2702] miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway.Dig Dis Sci. 2017 Dec;62(12):3447-3459. doi: 10.1007/s10620-017-4755-z. Epub 2017 Oct 13.
• [2703] MicroRNA-33a and let-7e inhibit human colorectal cancer progression by targeting ST8SIA1.Int J Biochem Cell Biol. 2017 Sep;90:48-58. doi: 10.1016/j.biocel.2017.07.016. Epub 2017 Jul 24.
• [2704] Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities.Neoplasia. 2018 Mar;20(3):289-294. doi: 10.1016/j.neo.2018.01.003. Epub 2018 Feb 19.
• [2705] Mutational and expressional analyses of STAG2 gene in solid cancers.Neoplasma. 2012;59(5):524-9. doi: 10.4149/neo_2012_067.
• [2706] Evaluation of miR-720 prognostic significance in patients with colorectal cancer.Tumour Biol. 2015 Feb;36(2):719-27. doi: 10.1007/s13277-014-2697-z. Epub 2014 Oct 7.
• [2707] JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841. Epub 2011 Nov 28.
• [2708] Silencing of stat4 gene inhibits cell proliferation and invasion of colorectal cancer cells.J Biol Regul Homeost Agents. 2015 Jan-Mar;29(1):85-92.
• [2709] Polymorphism of T-cell receptor gamma short tandem repeats as a susceptibility risk factor of hepatocellular carcinoma.Anticancer Res. 2006 Sep-Oct;26(5B):3787-91.
• [2710] SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization.Nat Commun. 2016 Dec 22;7:13875. doi: 10.1038/ncomms13875.
• [2711] Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23.
• [2712] Silencing Heat Shock Protein 27 Inhibits the Progression and Metastasis of Colorectal Cancer (CRC) by Maintaining the Stability of Stromal Interaction Molecule 1 (STIM1) Proteins.Cells. 2018 Dec 10;7(12):262. doi: 10.3390/cells7120262.
• [2713] Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.Hum Pathol. 2018 Sep;79:135-143. doi: 10.1016/j.humpath.2018.05.016. Epub 2018 Jun 5.
• [2714] Sodium butyrate induces autophagy in colorectal cancer cells through LKB1/AMPK signaling.J Physiol Biochem. 2019 Feb;75(1):53-63. doi: 10.1007/s13105-018-0651-z. Epub 2018 Oct 25.
• [2715] microRNA-222 promotes colorectal cancer cell migration and invasion by targeting MST3.FEBS Open Bio. 2019 May;9(5):901-913. doi: 10.1002/2211-5463.12623. Epub 2019 Apr 2.
• [2716] STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer.J Exp Clin Cancer Res. 2018 Jul 11;37(1):144. doi: 10.1186/s13046-018-0808-1.
• [2717] Serine/threonine kinase 31 promotes PDCD5-mediated apoptosis in p53-dependent human colon cancer cells.J Cell Physiol. 2019 Mar;234(3):2649-2658. doi: 10.1002/jcp.27079. Epub 2018 Aug 24.
• [2718] Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells.Cell Physiol Biochem. 2018;45(2):808-818. doi: 10.1159/000487172. Epub 2018 Jan 31.
• [2719] CHIP/Stub1 functions as a tumor suppressor and represses NF-B-mediated signaling in colorectal cancer.Carcinogenesis. 2014 May;35(5):983-91. doi: 10.1093/carcin/bgt393. Epub 2013 Dec 3.
• [2720] A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse.PLoS Genet. 2018 Jun 18;14(6):e1007432. doi: 10.1371/journal.pgen.1007432. eCollection 2018 Jun.
• [2721] STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-B pathway.Cell Death Dis. 2018 May 31;9(6):664. doi: 10.1038/s41419-018-0675-x.
• [2722] Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.Mol Cancer Res. 2015 Mar;13(3):510-23. doi: 10.1158/1541-7786.MCR-14-0372. Epub 2014 Dec 4.
• [2723] Discovery of Aberrant Alteration of Genome in Colorectal Cancer by Exome Sequencing.Am J Med Sci. 2019 Nov;358(5):340-349. doi: 10.1016/j.amjms.2019.07.012. Epub 2019 Aug 1.
• [2724] Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases.BMC Cancer. 2016 Jul 26;16:539. doi: 10.1186/s12885-016-2596-3.
• [2725] Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer.J Cancer Res Clin Oncol. 2015 Apr;141(4):661-9. doi: 10.1007/s00432-014-1854-5. Epub 2014 Oct 19.
• [2726] Systematic search for rare variants in Finnish early-onset colorectal cancer patients.Cancer Genet. 2015 Jan-Feb;208(1-2):35-40. doi: 10.1016/j.cancergen.2014.12.004. Epub 2014 Dec 31.
• [2727] SYNJ2 variant rs9365723 is associated with colorectal cancer risk in Chinese Han population.Int J Biol Markers. 2016 May 28;31(2):e138-43. doi: 10.5301/jbm.5000182.
• [2728] Synaptophysin expression as prognostic factor for survival in colorectal carcinomas.Rom J Morphol Embryol. 2017;58(4):1409-1415.
• [2729] Synaptotagmin7 Is Overexpressed In Colorectal Cancer And Regulates Colorectal Cancer Cell Proliferation.J Cancer. 2018 Jun 12;9(13):2349-2356. doi: 10.7150/jca.25098. eCollection 2018.
• [2730] TAB3 upregulates Survivin expression to promote colorectal cancer invasion and metastasis by binding to the TAK1-TRAF6 complex.Oncotarget. 2017 Nov 18;8(63):106565-106576. doi: 10.18632/oncotarget.22497. eCollection 2017 Dec 5.
• [2731] Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.Pathol Oncol Res. 2017 Jan;23(1):125-130. doi: 10.1007/s12253-016-0107-0. Epub 2016 Aug 29.
• [2732] Frameshift mutations of TAF1C gene, a core component for transcription by RNA polymerase I, and its regional heterogeneity in gastric and colorectal cancers.Pathology. 2015 Feb;47(2):101-4. doi: 10.1097/PAT.0000000000000212.
• [2733] Angiogenin and the MMP9-TIMP2 axis are up-regulated in proangiogenic, decidual NK-like cells from patients with colorectal cancer.FASEB J. 2018 Oct;32(10):5365-5377. doi: 10.1096/fj.201701103R. Epub 2018 May 15.
• [2734] Genome-wide differential genetic profiling characterizes colorectal cancers with genetic instability and specific routes to HLA class I loss and immune escape.Cancer Immunol Immunother. 2012 Jun;61(6):803-16. doi: 10.1007/s00262-011-1147-7. Epub 2011 Nov 10.
• [2735] Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer.J Transl Med. 2015 Aug 27;13:279. doi: 10.1186/s12967-015-0647-1.
• [2736] Association between polymorphisms of TAS2R16 and susceptibility to colorectal cancer.BMC Gastroenterol. 2017 Sep 15;17(1):104. doi: 10.1186/s12876-017-0659-9.
• [2737] BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells.Int J Cancer. 2012 Jan 15;130(2):328-37. doi: 10.1002/ijc.26029. Epub 2011 May 28.
• [2738] Increased expression of TBX2 is a novel independent prognostic biomarker of a worse outcome in colorectal cancer patients after curative surgery and a potential therapeutic target.Med Oncol. 2013 Dec;30(4):688. doi: 10.1007/s12032-013-0688-3. Epub 2013 Aug 20.
• [2739] Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.Gastroenterology. 2013 Apr;144(4):799-807.e24. doi: 10.1053/j.gastro.2012.12.020. Epub 2012 Dec 22.
• [2740] Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells.Genes (Basel). 2018 Jan 8;9(1):20. doi: 10.3390/genes9010020.
• [2741] Osteopontin-integrin engagement induces HIF-1-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.Oncotarget. 2017 Dec 22;9(4):4998-5015. doi: 10.18632/oncotarget.23578. eCollection 2018 Jan 12.
• [2742] Human telomerase reverse transcriptase recruits the -catenin/TCF-4 complex to transactivate chemokine (C-C motif) ligand 2 expression in colorectal cancer.Biomed Pharmacother. 2019 Apr;112:108700. doi: 10.1016/j.biopha.2019.108700. Epub 2019 Feb 26.
• [2743] Activation of WNT/-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations.Int J Cancer. 2019 Jan 15;144(2):389-401. doi: 10.1002/ijc.31662. Epub 2018 Nov 29.
• [2744] Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation.Cells. 2019 Jul 30;8(8):794. doi: 10.3390/cells8080794.
• [2745] A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk.Br J Nutr. 2013 Mar 28;109(6):984-9. doi: 10.1017/S0007114512002796. Epub 2012 Jul 16.
• [2746] Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells.Med Sci Monit. 2017 Jan 26;23:452-461. doi: 10.12659/msm.899595.
• [2747] TEAD1 enhances proliferation via activating SP1 in colorectal cancer.Biomed Pharmacother. 2016 Oct;83:496-501. doi: 10.1016/j.biopha.2016.06.058. Epub 2016 Jul 18.
• [2748] Expression and mechanism of microRNA-181A on incidence and survival in late liver metastases of colorectal cancer.Oncol Rep. 2016 Mar;35(3):1403-8. doi: 10.3892/or.2016.4546. Epub 2016 Jan 5.
• [2749] Mono-ADP-ribosylation of H3R117 traps 5mC hydroxylase TET1 to impair demethylation of tumor suppressor gene TFPI2.Oncogene. 2019 May;38(18):3488-3503. doi: 10.1038/s41388-018-0671-8. Epub 2019 Jan 16.
• [2750] Prognostic Significance of Mitochondrial Transcription Factor A Expression in Patients with Right- or Left-sided Colorectal Cancer.Anticancer Res. 2018 Jan;38(1):569-575. doi: 10.21873/anticanres.12261.
• [2751] TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway.J Exp Clin Cancer Res. 2018 Feb 13;37(1):27. doi: 10.1186/s13046-018-0683-9.
• [2752] TFAP2E methylation status and prognosis of patients with radically resected colorectal cancer.Oncology. 2015;88(2):122-32. doi: 10.1159/000362820. Epub 2014 Oct 23.
• [2753] TFCP2/TFCP2L1/UBP1 transcription factors in cancer.Cancer Lett. 2018 Apr 28;420:72-79. doi: 10.1016/j.canlet.2018.01.078. Epub 2018 Feb 7.
• [2754] The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.Oncogene. 2018 Mar;37(9):1205-1219. doi: 10.1038/s41388-017-0033-y. Epub 2017 Dec 15.
• [2755] Discovery of colorectal cancer biomarker candidates by membrane proteomic analysis and subsequent verification using selected reaction monitoring (SRM) and tissue microarray (TMA) analysis.Mol Cell Proteomics. 2014 Jun;13(6):1471-84. doi: 10.1074/mcp.M113.037093. Epub 2014 Mar 31.
• [2756] Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):53-8. doi: 10.1016/j.bbrc.2015.10.166. Epub 2015 Nov 3.
• [2757] miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1.Mol Cancer. 2017 Mar 4;16(1):53. doi: 10.1186/s12943-017-0625-8.
• [2758] RETRACTED: Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway.Cancer Lett. 2018 Nov 1;436:119-128. doi: 10.1016/j.canlet.2018.08.012. Epub 2018 Aug 14.
• [2759] Identification of a fluorescent small-molecule enhancer for therapeutic autophagy in colorectal cancer by targeting mitochondrial protein translocase TIM44.Gut. 2018 Feb;67(2):307-319. doi: 10.1136/gutjnl-2016-311909. Epub 2016 Nov 14.
• [2760] Strong association of tissue inhibitor of metalloproteinase (TIMP)-2 and -3 promoter single nucleotide polymorphisms with risk of colorectal cancer in ethnic Kashmiri population - a case control study.Biosci Rep. 2019 May 10;39(5):BSR20190478. doi: 10.1042/BSR20190478. Print 2019 May 31.
• [2761] Alu-related transcript of TJP2 gene as a marker for colorectal cancer.Gene. 2013 Jul 25;524(2):268-74. doi: 10.1016/j.gene.2013.04.006. Epub 2013 Apr 20.
• [2762] Characterization of Aes nuclear foci in colorectal cancer cells.J Biochem. 2016 Jan;159(1):133-40. doi: 10.1093/jb/mvv077. Epub 2015 Jul 29.
• [2763] TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway.Oncotarget. 2016 Jan 19;7(3):2878-88. doi: 10.18632/oncotarget.6694.
• [2764] MiRNA-206 suppresses PGE2-induced colorectal cancer cell proliferation, migration, and invasion by targetting TM4SF1.Biosci Rep. 2018 Sep 19;38(5):BSR20180664. doi: 10.1042/BSR20180664. Print 2018 Oct 31.
• [2765] The integrated pathway of TGF/Snail with TNF/NFB may facilitate the tumor-stroma interaction in the EMT process and colorectal cancer prognosis.Sci Rep. 2017 Jul 7;7(1):4915. doi: 10.1038/s41598-017-05280-6.
• [2766] Production of an anti-TM4SF5 monoclonal antibody and its application in the detection of TM4SF5 as a possible marker of a poor prognosis in colorectal cancer.Int J Oncol. 2018 Jul;53(1):275-285. doi: 10.3892/ijo.2018.4385. Epub 2018 Apr 26.
• [2767] Transposon mutagenesis screen in mice identifies TM9SF2 as a novel colorectal cancer oncogene.Sci Rep. 2018 Oct 17;8(1):15327. doi: 10.1038/s41598-018-33527-3.
• [2768] Genetic variant of TMBIM1 is associated with the susceptibility of colorectal cancer in the Chinese population.Clin Res Hepatol Gastroenterol. 2019 Jun;43(3):324-329. doi: 10.1016/j.clinre.2018.10.013. Epub 2018 Nov 15.
• [2769] Frameshift mutation of candidate tumor suppressor genes QK1 and TMEFF2 in gastric and colorectal cancers.Cancer Biomark. 2019;24(1):1-6. doi: 10.3233/CBM-160559.
• [2770] Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.Epigenetics. 2017 Jul 3;12(7):575-583. doi: 10.1080/15592294.2017.1341027. Epub 2017 Jul 5.
• [2771] TMEM25 is a candidate biomarker methylated and down-regulated in colorectal cancer.Dis Markers. 2013;34(2):93-104. doi: 10.3233/DMA-120948.
• [2772] TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/-catenin signalling.Nat Cell Biol. 2018 Dec;20(12):1421-1433. doi: 10.1038/s41556-018-0219-8. Epub 2018 Oct 29.
• [2773] TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability.Cancer Biol Ther. 2014 Mar 1;15(3):297-304. doi: 10.4161/cbt.27308. Epub 2013 Dec 12.
• [2774] SCC-S2 Facilitates Tumor Proliferation and Invasion via Activating Wnt Signaling and Depressing Hippo Signaling in Colorectal Cancer Cells and Predicts Poor Prognosis of Patients.J Histochem Cytochem. 2019 Jan;67(1):65-75. doi: 10.1369/0022155418799957. Epub 2018 Sep 14.
• [2775] TROY is a promising prognostic biomarker in patients with colorectal cancer.Oncol Lett. 2018 Apr;15(4):5989-5994. doi: 10.3892/ol.2018.8079. Epub 2018 Feb 16.
• [2776] Elevated transgelin/TNS1 expression is a potential biomarker in human colorectal cancer.Oncotarget. 2017 Dec 15;9(1):1107-1113. doi: 10.18632/oncotarget.23275. eCollection 2018 Jan 2.
• [2777] TOMM20 as a potential therapeutic target of colorectal cancer.BMB Rep. 2019 Dec;52(12):712-717. doi: 10.5483/BMBRep.2019.52.12.249.
• [2778] Cytotoxic T lymphocyte response to peptide vaccination predicts survival in stage III colorectal cancer.Cancer Sci. 2018 May;109(5):1545-1551. doi: 10.1111/cas.13547. Epub 2018 Mar 31.
• [2779] Novel somatic frameshift mutations of genes related to cell cycle and DNA damage response in gastric and colorectal cancers with microsatellite instability.Tumori. 2010 Nov-Dec;96(6):1004-9.
• [2780] Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer.Cancer Med. 2019 Jul;8(7):3428-3436. doi: 10.1002/cam4.2215. Epub 2019 May 15.
• [2781] Epigenetic silencing of TPM2 contributes to colorectal cancer progression upon RhoA activation.Tumour Biol. 2016 Sep;37(9):12477-12483. doi: 10.1007/s13277-016-5103-1. Epub 2016 Jun 23.
• [2782] Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer.Int J Mol Sci. 2019 Dec 2;20(23):6082. doi: 10.3390/ijms20236082.
• [2783] Knockdown of Tubulin Polymerization Promoting Protein Family Member 3 inhibits cell proliferation and invasion in human colorectal cancer.J Cancer. 2017 Jul 1;8(10):1750-1758. doi: 10.7150/jca.18943. eCollection 2017.
• [2784] Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.J Cancer Res Clin Oncol. 2015 Jan;141(1):35-41. doi: 10.1007/s00432-014-1780-6. Epub 2014 Jul 31.
• [2785] MiR-141-3p inhibits cell proliferation, migration and invasion by targeting TRAF5 in colorectal cancer.Biochem Biophys Res Commun. 2019 Jun 30;514(3):699-705. doi: 10.1016/j.bbrc.2019.05.002. Epub 2019 May 9.
• [2786] Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner.BMC Cancer. 2014 May 10;14:330. doi: 10.1186/1471-2407-14-330.
• [2787] The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.Mol Carcinog. 2014 Feb;53 Suppl 1:E72-84. doi: 10.1002/mc.22031. Epub 2013 Apr 26.
• [2788] Knockdown of NIK and IKK-Binding Protein (NIBP) Reduces Colorectal Cancer Metastasis through Down-Regulation of the Canonical NF- Signaling Pathway and Suppression of MAPK Signaling Mediated through ERK and JNK.PLoS One. 2017 Jan 26;12(1):e0170595. doi: 10.1371/journal.pone.0170595. eCollection 2017.
• [2789] DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.Clin Epigenetics. 2019 May 3;11(1):67. doi: 10.1186/s13148-019-0666-5.
• [2790] TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.Oncotarget. 2017 Jul 18;8(29):47931-47942. doi: 10.18632/oncotarget.18201.
• [2791] TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling.Mol Cancer. 2018 Dec 12;17(1):172. doi: 10.1186/s12943-018-0922-x.
• [2792] TRIB3 Interacts With -Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.Gastroenterology. 2019 Feb;156(3):708-721.e15. doi: 10.1053/j.gastro.2018.10.031. Epub 2018 Oct 24.
• [2793] Theragnosis by a miR-141-3p molecular beacon: simultaneous detection and sensitization of 5-fluorouracil resistant colorectal cancer cells through the activation of the TRIM13-associated apoptotic pathway.Chem Commun (Camb). 2019 Jul 4;55(52):7466-7469. doi: 10.1039/c9cc01944h. Epub 2019 Jun 11.
• [2794] TRIM2 is a novel promoter of human colorectal cancer.Scand J Gastroenterol. 2019 Feb;54(2):210-218. doi: 10.1080/00365521.2019.1575463. Epub 2019 Mar 27.
• [2795] TRIM29 facilitates the epithelial-to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/-catenin signaling pathway.J Exp Clin Cancer Res. 2019 Feb 27;38(1):104. doi: 10.1186/s13046-019-1098-y.
• [2796] TRIM44 Promotes Colorectal Cancer Proliferation, Migration, and Invasion Through the Akt/mTOR Signaling Pathway.Onco Targets Ther. 2019 Dec 9;12:10693-10701. doi: 10.2147/OTT.S228637. eCollection 2019.
• [2797] TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling.Cancer Cell Int. 2019 Mar 14;19:57. doi: 10.1186/s12935-019-0775-4. eCollection 2019.
• [2798] Downregulation of TRIM58 expression is associated with a poor patient outcome and enhances colorectal cancer cell invasion.Oncol Rep. 2018 Sep;40(3):1251-1260. doi: 10.3892/or.2018.6525. Epub 2018 Jun 26.
• [2799] Knockdown of TRIM66 inhibits cell proliferation, migration and invasion in colorectal cancer through JAK2/STAT3 pathway.Life Sci. 2019 Oct 15;235:116799. doi: 10.1016/j.lfs.2019.116799. Epub 2019 Aug 28.
• [2800] TRIM67 Activates p53 to Suppress Colorectal Cancer Initiation and Progression.Cancer Res. 2019 Aug 15;79(16):4086-4098. doi: 10.1158/0008-5472.CAN-18-3614. Epub 2019 Jun 25.
• [2801] Lentivirus-mediated RNA interference of tripartite motif 68 inhibits the proliferation of colorectal cancer cell lines SW1116 and HCT116 in vitro.Oncol Lett. 2017 Apr;13(4):2649-2655. doi: 10.3892/ol.2017.5787. Epub 2017 Feb 28.
• [2802] TRIM72 Immunohistochemical Expression Can Predict Relapse in Colorectal Carcinoma.Pathol Oncol Res. 2020 Apr;26(2):861-865. doi: 10.1007/s12253-019-00629-w. Epub 2019 Mar 9.
• [2803] TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours.Mol Cancer. 2017 Mar 21;16(1):67. doi: 10.1186/s12943-017-0634-7.
• [2804] Inference of Environmental Factor-Microbe and Microbe-Microbe Associations from Metagenomic Data Using a Hierarchical Bayesian Statistical Model.Cell Syst. 2017 Jan 25;4(1):129-137.e5. doi: 10.1016/j.cels.2016.12.012.
• [2805] TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer.Cell Death Dis. 2018 Mar 14;9(3):402. doi: 10.1038/s41419-018-0434-z.
• [2806] MicroRNA-519d-3p inhibits cell proliferation and migration by targeting TROAP in colorectal cancer.Biomed Pharmacother. 2018 Sep;105:879-886. doi: 10.1016/j.biopha.2018.04.114. Epub 2018 Jun 18.
• [2807] Low levels of TSC22 enhance tumorigenesis by inducing cell proliferation in colorectal cancer.Biochem Biophys Res Commun. 2018 Mar 18;497(4):1062-1067. doi: 10.1016/j.bbrc.2018.02.177. Epub 2018 Feb 24.
• [2808] TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer.Int J Oncol. 2016 Sep;49(3):1046-56. doi: 10.3892/ijo.2016.3599. Epub 2016 Jul 4.
• [2809] MicroRNA-mRNA interaction network using TSK-type recurrent neural fuzzy network.Gene. 2013 Feb 25;515(2):385-90. doi: 10.1016/j.gene.2012.12.063. Epub 2012 Dec 20.
• [2810] MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma.Oncotarget. 2014 Dec 15;5(23):12083-96. doi: 10.18632/oncotarget.2499.
• [2811] Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis.Am J Transl Res. 2017 Feb 15;9(2):812-822. eCollection 2017.
• [2812] miR-19-5p Enhances Tumorigenesis in Human Colorectal Cancer Cells by Targeting TSPYL5.DNA Cell Biol. 2018 Jan;37(1):23-30. doi: 10.1089/dna.2017.3804. Epub 2017 Dec 14.
• [2813] Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer.Oncotarget. 2014 Feb 15;5(3):853-9. doi: 10.18632/oncotarget.1781.
• [2814] Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.EMBO J. 2014 Oct 1;33(19):2247-60. doi: 10.15252/embj.201488466. Epub 2014 Sep 1.
• [2815] ADAM15 to 51 integrin switch in colon carcinoma cells: a late event in cancer progression associated with tumor dedifferentiation and poor prognosis.Int J Cancer. 2012 Jan 15;130(2):278-87. doi: 10.1002/ijc.25891. Epub 2011 Nov 9.
• [2816] A complex of 6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6.EMBO Mol Med. 2012 Nov;4(11):1156-75. doi: 10.1002/emmm.201101164. Epub 2012 Oct 16.
• [2817] ALEX1 suppresses colony formation ability of human colorectal carcinoma cell lines.Cancer Sci. 2012 Jul;103(7):1267-71. doi: 10.1111/j.1349-7006.2012.02300.x. Epub 2012 May 17.
• [2818] Increased expression of ATG10 in colorectal cancer is associated with lymphovascular invasion and lymph node metastasis.PLoS One. 2012;7(12):e52705. doi: 10.1371/journal.pone.0052705. Epub 2012 Dec 20.
• [2819] Aberrant SERCA3 expression during the colorectal adenoma-adenocarcinoma sequence.Oncol Rep. 2014 Jan;31(1):232-40. doi: 10.3892/or.2013.2837. Epub 2013 Nov 7.
• [2820] cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.PLoS One. 2012;7(2):e30477. doi: 10.1371/journal.pone.0030477. Epub 2012 Feb 17.
• [2821] CADM1/TSLC1 inactivation by promoter hypermethylation is a frequent event in colorectal carcinogenesis and correlates with late stages of the disease.Int J Cancer. 2011 Jan 15;128(2):266-73. doi: 10.1002/ijc.25356. Epub 2010 Mar 25.
• [2822] Up-regulated expression of l-caldesmon associated with malignancy of colorectal cancer.BMC Cancer. 2012 Dec 17;12:601. doi: 10.1186/1471-2407-12-601.
• [2823] Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines.Oncol Rep. 2012 Nov;28(5):1551-8. doi: 10.3892/or.2012.1967. Epub 2012 Aug 10.
• [2824] A functional variant of IC53 correlates with the late onset of colorectal cancer.Mol Med. 2011;17(7-8):607-18. doi: 10.2119/molmed.2010.00192. Epub 2011 Mar 2.
• [2825] The TERT variant rs2736100 is associated with colorectal cancer risk.Br J Cancer. 2012 Sep 4;107(6):1001-8. doi: 10.1038/bjc.2012.329. Epub 2012 Aug 9.
• [2826] The prognostic value of CSN6 expression in upper tract urothelial carcinomas.Kaohsiung J Med Sci. 2019 Sep;35(9):559-565. doi: 10.1002/kjm2.12104. Epub 2019 Jul 24.
• [2827] Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.Cancer Biol Ther. 2011 Mar 15;11(6):599-608. doi: 10.4161/cbt.11.6.14670. Epub 2011 Mar 15.
• [2828] A novel test for gene-ancestry interactions in genome-wide association data.PLoS One. 2012;7(12):e48687. doi: 10.1371/journal.pone.0048687. Epub 2012 Dec 6.
• [2829] PNAS-4 expression and its relationship to p53 in colorectal cancer.Mol Biol Rep. 2012 Jan;39(1):243-9. doi: 10.1007/s11033-011-0732-3. Epub 2011 May 10.
• [2830] CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.Cell Oncol (Dordr). 2012 Aug;35(4):293-300. doi: 10.1007/s13402-012-0088-2. Epub 2012 Jun 19.
• [2831] Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.Int J Colorectal Dis. 2012 Nov;27(11):1391-9. doi: 10.1007/s00384-012-1460-4. Epub 2012 Mar 23.
• [2832] Genetics of ulcerative colitis.Inflamm Bowel Dis. 2011 Mar;17(3):831-48. doi: 10.1002/ibd.21375. Epub 2010 Nov 12.
• [2833] Significance of ELF3 mRNA expression for detection of lymph node metastases of colorectal cancer.Anticancer Res. 2012 Sep;32(9):3753-8.
• [2834] A systems biology approach to the global analysis of transcription factors in colorectal cancer.BMC Cancer. 2012 Aug 1;12:331. doi: 10.1186/1471-2407-12-331.
• [2835] Differential roles of EPS8 in carcinogenesis: loss of protein expression in a subset of colorectal carcinoma and adenoma.World J Gastroenterol. 2012 Aug 7;18(29):3896-903. doi: 10.3748/wjg.v18.i29.3896.
• [2836] Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer.Nat Genet. 2018 Oct;50(10):1375-1380. doi: 10.1038/s41588-018-0211-z. Epub 2018 Sep 17.
• [2837] A Boolean-based systems biology approach to predict novel genes associated with cancer: Application to colorectal cancer.BMC Syst Biol. 2011 Feb 26;5:35. doi: 10.1186/1752-0509-5-35.
• [2838] Candidate driver genes in microsatellite-unstable colorectal cancer.Int J Cancer. 2012 Apr 1;130(7):1558-66. doi: 10.1002/ijc.26167. Epub 2011 Aug 3.
• [2839] Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer.Clin Exp Metastasis. 2012 Dec;29(8):915-25. doi: 10.1007/s10585-012-9480-6. Epub 2012 May 3.
• [2840] Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers.Oncogene. 2012 Mar 8;31(10):1242-53. doi: 10.1038/onc.2011.320. Epub 2011 Aug 1.
• [2841] Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice.PLoS One. 2019 Aug 28;14(8):e0221751. doi: 10.1371/journal.pone.0221751. eCollection 2019.
• [2842] Genome-wide significant risk associations for mucinous ovarian carcinoma.Nat Genet. 2015 Aug;47(8):888-97. doi: 10.1038/ng.3336. Epub 2015 Jun 15.
• [2843] Targeted disruption of the BCL9/-catenin complex inhibits oncogenic Wnt signaling.Sci Transl Med. 2012 Aug 22;4(148):148ra117. doi: 10.1126/scitranslmed.3003808.
• [2844] Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas.J Biol Chem. 2011 Jun 24;286(25):22403-13. doi: 10.1074/jbc.M110.215301. Epub 2011 Apr 22.
• [2845] The expression of leucine-rich repeat gene family members in colorectal cancer.Exp Biol Med (Maywood). 2012 Oct;237(10):1123-8. doi: 10.1258/ebm.2012.012042. Epub 2012 Oct 8.
• [2846] GCF2/LRRFIP1 promotes colorectal cancer metastasis and liver invasion through integrin-dependent RhoA activation.Cancer Lett. 2012 Dec 1;325(1):99-107. doi: 10.1016/j.canlet.2012.06.012. Epub 2012 Jun 28.
• [2847] Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer.Br J Cancer. 2012 Nov 6;107(10):1761-5. doi: 10.1038/bjc.2012.428. Epub 2012 Sep 20.
• [2848] MPP3 inactivation by promoter CpG islands hypermethylation in colorectal carcinogenesis.Cancer Biomark. 2012;11(2-3):99-106. doi: 10.3233/CBM-2012-0264.
• [2849] Proteomic analysis reveals overexpression of moesin and cytokeratin 17 proteins in colorectal carcinoma.Oncol Rep. 2012 Mar;27(3):608-20. doi: 10.3892/or.2011.1545. Epub 2011 Nov 10.
• [2850] T([20]) repeat in the 3'-untranslated region of the MT1X gene: a marker with high sensitivity and specificity to detect microsatellite instability in colorectal cancer.Int J Colorectal Dis. 2012 May;27(5):647-56. doi: 10.1007/s00384-011-1365-7. Epub 2011 Nov 23.
• [2851] A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer.Colorectal Dis. 2012 Mar;14(3):e80-9. doi: 10.1111/j.1463-1318.2011.02858.x.
• [2852] Brush border myosin Ia has tumor suppressor activity in the intestine.Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. doi: 10.1073/pnas.1108411109. Epub 2012 Jan 18.
• [2853] Potential role of a navigator gene NAV3 in colorectal cancer.Br J Cancer. 2012 Jan 31;106(3):517-24. doi: 10.1038/bjc.2011.553. Epub 2011 Dec 15.
• [2854] Inhibitory effect of upregulated DR-nm23 expression on invasion and metastasis in colorectal cancer.Eur J Cancer Prev. 2013 Nov;22(6):512-22. doi: 10.1097/CEJ.0b013e328361625d.
• [2855] Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers.DNA Cell Biol. 2012 May;31(5):660-71. doi: 10.1089/dna.2011.1446. Epub 2011 Dec 2.
• [2856] O-linked -N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl--D-glucosaminidase silencing on cell phenotype and transcriptome.J Biol Chem. 2012 Aug 17;287(34):28755-69. doi: 10.1074/jbc.M112.345546. Epub 2012 Jun 22.
• [2857] Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.J Genet Genomics. 2012 Aug 20;39(8):369-74. doi: 10.1016/j.jgg.2012.05.007. Epub 2012 Jun 8.
• [2858] PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers.Carcinogenesis. 2012 Nov;33(11):2228-35. doi: 10.1093/carcin/bgs245. Epub 2012 Jul 24.
• [2859] Expression of PEBP4 protein correlates with the invasion and metastasis of colorectal cancer.Tumour Biol. 2012 Feb;33(1):267-73. doi: 10.1007/s13277-011-0279-x. Epub 2011 Nov 29.
• [2860] DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT.Cancer Prev Res (Phila). 2012 Mar;5(3):464-72. doi: 10.1158/1940-6207.CAPR-11-0315. Epub 2011 Dec 1.
• [2861] Silencing phospholipid scramblase 1 expression by RNA interference in colorectal cancer and metastatic liver cancer.Hepatobiliary Pancreat Dis Int. 2012 Aug 15;11(4):393-400. doi: 10.1016/s1499-3872(12)60197-0.
• [2862] Aberrant methylation of PSD disturbs Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis in ulcerative colitis-associated carcinogenesis.Int J Oncol. 2012 Apr;40(4):942-50. doi: 10.3892/ijo.2011.1301. Epub 2011 Dec 15.
• [2863] A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer.J Med Genet. 2012 Jul;49(7):429-32. doi: 10.1136/jmedgenet-2012-100852. Epub 2012 May 31.
• [2864] Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation.Int J Biochem Cell Biol. 2012 Sep;44(9):1465-72. doi: 10.1016/j.biocel.2012.05.015. Epub 2012 May 27.
• [2865] SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.Mol Cancer Res. 2012 Jun;10(6):787-99. doi: 10.1158/1541-7786.MCR-11-0462. Epub 2012 Apr 11.
• [2866] A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.Mol Cancer Ther. 2012 Jan;11(1):119-31. doi: 10.1158/1535-7163.MCT-11-0510. Epub 2011 Oct 25.
• [2867] Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile.Cancer Genomics Proteomics. 2012 Mar-Apr;9(2):67-75.
• [2868] Rare MDM4 gene amplification in colorectal cancer: The principle of a mutually exclusive relationship between MDM alteration and TP53 inactivation is not applicable.Oncol Rep. 2011 Jul;26(1):49-54. doi: 10.3892/or.2011.1270. Epub 2011 Apr 18.
• [2869] Loss of INI1 expression in colorectal carcinoma is associated with high tumor grade, poor survival, BRAFV600E mutation, and mismatch repair deficiency.Hum Pathol. 2016 Sep;55:83-90. doi: 10.1016/j.humpath.2016.04.018. Epub 2016 May 14.
• [2870] Sperm-associated antigen 9 is a novel biomarker for colorectal cancer and is involved in tumor growth and tumorigenicity.Am J Pathol. 2011 Mar;178(3):1009-20. doi: 10.1016/j.ajpath.2010.11.047.
• [2871] Analysis of select members of the E26 (ETS) transcription factors family in colorectal cancer.Virchows Arch. 2011 Apr;458(4):421-30. doi: 10.1007/s00428-011-1053-6. Epub 2011 Feb 12.
• [2872] Analysis of exosome release and its prognostic value in human colorectal cancer.Genes Chromosomes Cancer. 2012 Apr;51(4):409-18. doi: 10.1002/gcc.21926.
• [2873] Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.Mol Carcinog. 2012 Sep;51(9):746-53. doi: 10.1002/mc.20843. Epub 2011 Aug 30.
• [2874] Genome-wide screening for methylation-silenced genes in colorectal cancer.Int J Oncol. 2012 Aug;41(2):490-6. doi: 10.3892/ijo.2012.1500. Epub 2012 May 30.