Details of Disease

General Information of Disease (ID: DISDRE0J)

Disease Name Colon adenocarcinoma
Synonyms COAD; colonic adenocarcinoma; colon adenocarcinoma; adenocarcinoma of the colon; adenocarcinoma of colon; adenocarcinoma - colon
Definition A carcinoma that arises from glandular epithelial cells of the colon
Disease Hierarchy
DISJYKUO: Colon carcinoma
DIS3IHTY: Adenocarcinoma
DISPQOUB: Colorectal adenocarcinoma
DISDRE0J: Colon adenocarcinoma
Disease Identifiers
MONDO ID
MONDO_0002271
UMLS CUI
C0338106
MedGen ID
137834
HPO ID
HP:0040276

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 8 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Bevacizumab DMSD1UN Approved Monoclonal antibody [1]
Capecitabine DMTS85L Approved Small molecular drug [2]
Fluorouracil DMUM7HZ Approved Small molecular drug [3]
Gefitinib DM15F0X Approved Small molecular drug [4]
Irinotecan DMP6SC2 Approved Small molecular drug [5]
Leucovorin DMUAZWG Approved Small molecular drug [6]
Levoleucovorin DMH5LME Approved Small molecular drug [7]
Oxaliplatin DMQNWRD Approved Small molecular drug [8]
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⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 25 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CCNA2 TTAMQ62 Limited Altered Expression [9]
FECH TTQ6VF4 Limited Altered Expression [10]
FUT3 TTUPAD7 Limited Altered Expression [11]
GRPR TTC1MVT Limited Genetic Variation [12]
KLK6 TTLPF4X Limited Biomarker [13]
PLCB1 TTLPGU7 Limited Altered Expression [14]
PLD2 TTRLMKF Limited Biomarker [15]
PTK6 TT6TH8V Limited Altered Expression [16]
PTPN13 TT405FP Limited Altered Expression [17]
SIK1 TT1H6LC Limited Altered Expression [18]
SLC5A1 TT2UE56 Limited Biomarker [19]
STC2 TT4EFTR Limited Altered Expression [20]
XPNPEP2 TTI9MBZ Limited Biomarker [21]
YY1AP1 TTYED1Q Limited Altered Expression [22]
CD58 TT5KSBY Strong Biomarker [23]
CEACAM5 TTY6DTE Strong Biomarker [24]
FUT4 TTNV1KZ Strong Altered Expression [25]
GPR182 TTT23CG Strong Altered Expression [26]
HMGB1 TTWQYB7 Strong Biomarker [27]
HSD17B13 TTDJYZR Strong Altered Expression [28]
LGR5 TTTSGRH Strong Altered Expression [29]
MGMT TTJ8DV7 Strong Biomarker [30]
OLFM4 TTK1CX7 Strong Genetic Variation [31]
PYY TTVFJLX Strong Altered Expression [32]
VEGFC TT0QUFV Strong Biomarker [33]
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⏷ Show the Full List of 25 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC9A6 DTN0JXW Limited Altered Expression [34]
SLC2A5 DTOR02F Strong Biomarker [35]
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This Disease Is Related to 4 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
FUT10 DEP8X02 Limited Altered Expression [36]
FUT11 DERG61P Limited Altered Expression [36]
HSD17B7 DEDMWFX Strong Altered Expression [28]
SI DE5EO4Y Strong Altered Expression [37]
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This Disease Is Related to 72 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AEBP1 OTBI1RZ6 Limited Biomarker [38]
B3GNT7 OT8UTTXF Limited Altered Expression [39]
BBS2 OTPF9JIB Limited Altered Expression [40]
BCS1L OT5PY5CY Limited Biomarker [41]
CALB2 OTSNMCG9 Limited Biomarker [42]
CCNC OTMVK4K4 Limited Altered Expression [43]
CETN1 OTGQ8JOZ Limited Biomarker [42]
CNMD OTHND8EL Limited Biomarker [44]
COL8A1 OTWBTED2 Limited Altered Expression [45]
CSAD OT3I2G0A Limited Biomarker [46]
CXCL3 OTSL94KH Limited Biomarker [47]
CYP2W1 OTXSB1AE Limited Altered Expression [48]
DDB2 OTO8HVVB Limited Biomarker [49]
EEF1A1 OT00THXS Limited Altered Expression [50]
FBLN1 OT5MHHOP Limited Altered Expression [51]
FUT5 OTOPGL9M Limited Altered Expression [36]
FUT6 OTBZUQ7F Limited Biomarker [11]
FUT7 OTJF6BSN Limited Altered Expression [36]
FUT9 OTLIJBQY Limited Altered Expression [36]
GLS2 OT08MSHL Limited Altered Expression [52]
HOXB9 OTMVHQOU Limited Altered Expression [53]
HSPH1 OTVRR73T Limited Altered Expression [54]
JMJD4 OTYZGH63 Limited Altered Expression [55]
KLK13 OT8LOD2U Limited Biomarker [56]
LAMB1 OT6J9LJR Limited Biomarker [57]
LGALS4 OTKQCG0H Limited Biomarker [58]
MACC1 OTV3DLX0 Limited Biomarker [59]
MAP2K6 OTK13JKC Limited Biomarker [60]
MUC5B OTPW6K5C Limited Altered Expression [61]
MUC6 OTPVL723 Limited Biomarker [62]
NFE2L3 OT1MGXT0 Limited Altered Expression [63]
NONO OTN36Q6U Limited Biomarker [64]
PGP OT6QQ7OR Limited Biomarker [65]
PLA2G10 OTRZ2L5A Limited Altered Expression [66]
PLIN2 OTRXJ9UN Limited Biomarker [67]
RALY OT78NNWY Limited Biomarker [64]
RNF123 OTL59S8J Limited Biomarker [68]
SDF4 OTQ7WFYW Limited Biomarker [42]
SEC61A1 OTLBE3CB Limited Biomarker [69]
SENP3 OTFQDOMC Limited Biomarker [70]
SEPTIN9 OT1VMRFQ Limited Posttranslational Modification [71]
SETDB1 OTWVUA1B Limited Biomarker [72]
TAF1 OTDYS5G4 Limited Biomarker [73]
TAF4B OTCICY31 Limited Biomarker [74]
TGIF2LX OTLBWKZA Limited Biomarker [75]
TNNT1 OT8PBOAR Limited Biomarker [76]
APC OTKV0TIK Disputed Biomarker [77]
CDX2 OTCG4TSY moderate Biomarker [78]
CFHR1 OT72R16T moderate Biomarker [79]
DLD OT378CU9 moderate Biomarker [80]
MCM8 OTC93H3S moderate Altered Expression [81]
PTPRD OTZPJ3GX moderate Genetic Variation [82]
ACSL4 OTI71MUJ Strong Altered Expression [83]
CDX1 OTOHTMJE Strong Biomarker [84]
CKMT1A OTCINHH5 Strong Altered Expression [85]
CRB3 OTQKPTMU Strong Altered Expression [86]
CUL4B OT2QX4DO Strong Biomarker [87]
DHRS11 OTU3J0ZL Strong Altered Expression [28]
ESS2 OTZ08VCZ Strong Biomarker [88]
GALNT6 OTOQQVH1 Strong Biomarker [89]
GUCA2A OTUSF75G Strong Altered Expression [90]
JAG1 OT3LGT6K Strong Biomarker [91]
LAYN OT9A9Q1X Strong Altered Expression [92]
MFAP5 OT46VXSG Strong Biomarker [93]
MPST OTCDPH5D Strong Biomarker [94]
MSH6 OT46FP09 Strong Genetic Variation [95]
PNPT1 OTBR2Q0F Strong Altered Expression [96]
PPA1 OTHZK1QB Strong Biomarker [97]
PPP1R9B OTDCTHTT Strong Altered Expression [98]
CDK5RAP3 OTC0Q2QS Definitive Altered Expression [99]
DDX53 OTHK3EGZ Definitive Biomarker [100]
TBC1D9 OTSSCTB5 Definitive Altered Expression [101]
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⏷ Show the Full List of 72 DOT(s)

References

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2 Capecitabine FDA Label
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