Details of the Drug Excipient

General Information of Drug Inactive Ingredient (DIG) (ID: E00516)

DIG Name
Sorbitan tristearate
Synonyms
Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; [2-(4-hydroxy-3-octadecanoyloxyoxolan-2-yl)-2-octadecanoyloxyethyl] octadecanoate
DIG Function
Dispersing agent; Emulsifying agent; Solubilizing agent; Surfactant; Suspending agent; Vaccine adjuvant
Formula
C60H114O8
Canonical SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC
InChI
1S/C60H114O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h54-55,59-61H,4-53H2,1-3H3
InChIKey
IJCWFDPJFXGQBN-UHFFFAOYSA-N
Physicochemical Properties Molecular Weight 963.5 Topological Polar Surface Area 108
XlogP 24.3 Complexity 1100
Heavy Atom Count 68 Rotatable Bond Count 56
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 8

Full List of Drug(s) Co-administrated with This DIG

14 Approved Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Amcinonide DMM1JL9 Exanthem [] Amcinonide 0.1% lotion F23617
Betamethasone DMAHJEF Acute adrenal insufficiency [] Betamethasone 0.05% ointment F23642
Cangrelor DM8JRH0 Thrombosis [DB61-GB90] Cangrelor 50mg/vial powder F23098
Cladribine DM3JDRP Hairy cell leukaemia [2A82.2] Cladribine 10mg tablet F23688
Diazoxide DML1538 Congenital hyperinsulinism [5A4Y] Diazoxide 1.5g/30ml suspension F23709
Enzalutamide DMGL19D Prostate cancer [2C82.0] Enzalutamide 40mg capsule F23734
Gentamicin DMKINJO Bacteremia [1A73] Gentamicin 0.1% ointment F23760
Halobetasol Propionate DM3GB6S Inflammation [1A00-CA43.1] Halobetasol Propionate 0.01% lotion F23767
Larotrectinib DM26CQR Solid tumour/cancer [2A00-2F9Z] Larotrectinib 20 mg/ml solution F24272
Raltegravir DMYURI6 Human immunodeficiency virus infection [1C62] Raltegravir Potassium eq 100mg base/packet powder F23528
Ranitidine DM0GUSX Gastric ulcer [DA60] Ranitidine Hydrochloride eq 15 mg base/mL syrup F23533
Stiripentol DMMSDOY Dravet syndrome [8A61.11] Stiripentol 250 mg powder F24373
Tamoxifen DMLB0EZ Breast cancer [2C60-2C65] Tamoxifen Citrate eq 20mg base/10ml solution F23556
Tofacitinib DMBS370 Rheumatoid arthritis [FA20] Tofacitinib Citrate eq 22mg base extended release tablet F23570
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⏷ Show the Full List of 14 Approved Drug(s)
1 Investigative Drug(s) Co-administrated with This DIG
Drug Name Drug ID Indication Formulation Name Formulation ID
Oxybutynine DMJPBAX Obsolete neurogenic bladder [] Oxybutynin 5mg/5ml Syrup F23501
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