Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTN9D8E)

• DTT Name: Glutamate receptor ionotropic NMDA 2B (NMDAR2B) DTT Info
• UniProt ID: NMDE2_HUMAN
• Gene Name: GRIN2B

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha 1-PI	DMXC1K9	Alpha-1 antitrypsin deficiency	5C5A	Approved	[1]

8 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CERC-301	DMSABRI	Major depressive disorder	6A70.3	Phase 2	[2]
CP-101,606	DMIU19E	Parkinson disease	8A00.0	Phase 2	[3]
ELIPRODIL	DMIOGZM	Multiple sclerosis	8A40	Phase 2	[4]
MIJ821	DMN45RI	Major depressive disorder	6A70.3	Phase 2	[5]
RGH-896	DMCHZAN	Peripheral neuropathy	8C0Z	Phase 2	[6]
EVT100	DMAKWQD	Major depressive disorder	6A70.3	Phase 1	[7]
NBQX	DMPHZI5	Neurological disorder	6B60	Phase 1	[8]
Neu-2000	DMNJTLC	Cardiac arrest	MC82	Phase 1	[9]

14 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
EVT-101	DMOYMGV	Neuropathic pain	8E43.0	Discontinued in Phase 2	[10]
YM-90K	DMWRT4L	Convulsion	8A68.Z	Discontinued in Phase 2	[11]
Besonprodil	DMMAFQP	Parkinson disease	8A00.0	Discontinued in Phase 1	[10]
EVT-103	DM9450Z	Major depressive disorder	6A70.3	Discontinued in Phase 1	[12]
Dizocilpine	DMMGYXR	Cerebrovascular ischaemia	8B1Z	Terminated	[13]
L-687414	DM56VPY	N. A.	N. A.	Terminated	[14]
L-689560	DMCVY4U	Neurodegenerative disorder	8A20-8A23	Terminated	[15]
L-695902	DMT1DNS	N. A.	N. A.	Terminated	[14]
L-698532	DMO9HM7	Neurological disorder	6B60	Terminated	[16]
L-698544	DMLRBN1	Alzheimer disease	8A20	Terminated	[14]
L-701324	DMAIJSX	Cerebrovascular ischaemia	8B1Z	Terminated	[16]
MDL-105519	DMHUJCI	N. A.	N. A.	Terminated	[17]
RO-25-6981	DM3H921	Cancer related pain	MG30	Terminated	[18]
RPR-104632	DM9L50N	N. A.	N. A.	Terminated	[19]

101 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(+)-HA966	DMKWEAJ	Discovery agent	N.A.	Investigative	[15]
(D)-Ala-Pro-Glu	DMGXTSB	Discovery agent	N.A.	Investigative	[20]
(R)-2-Amino-5-phosphono-pentanoic acid	DMSY4CK	Discovery agent	N.A.	Investigative	[21]
(R)-2-Amino-7-phosphono-heptanoic acid	DM4XEHR	Discovery agent	N.A.	Investigative	[21]
(RS)-(tetrazol-5-yl)glycine	DMYZCRF	Discovery agent	N.A.	Investigative	[15]
1,3-ditolylguanidine	DM04KS1	Discovery agent	N.A.	Investigative	[22]
2-(4-benzyl-piperidin-1-ylmethyl)-1H-indol-6-ol	DMFGCS1	Discovery agent	N.A.	Investigative	[23]
2-(4-Phenoxy-benzyl)-1H-benzoimidazole	DM65IF1	Discovery agent	N.A.	Investigative	[24]
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-4-ol	DM3HANW	Discovery agent	N.A.	Investigative	[24]
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ol	DMFO19B	Discovery agent	N.A.	Investigative	[24]
2-(4-Phenoxy-benzyl)-3H-benzoimidazol-5-ylamine	DMJSBFU	Discovery agent	N.A.	Investigative	[24]
2-Methylamino-succinic acid(NMDA)	DMKP6BM	Discovery agent	N.A.	Investigative	[15], [25]
2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline	DM5D09Q	Discovery agent	N.A.	Investigative	[26]
3-Benzoyl-7-chloro-4-hydroxy-1H-quinolin-2-one	DMAH4DG	Discovery agent	N.A.	Investigative	[14]
3-Hydroxy-1H-benzo[b]azepine-2,5-dione	DMZSOPU	Discovery agent	N.A.	Investigative	[27]
3-Hydroxy-6-methyl-1H-benzo[b]azepine-2,5-dione	DMYR350	Discovery agent	N.A.	Investigative	[27]
3-Hydroxy-7-nitro-1H-benzo[b]azepine-2,5-dione	DMTEJOY	Discovery agent	N.A.	Investigative	[27]
3-Hydroxy-8-methyl-1H-benzo[b]azepine-2,5-dione	DM7HKIF	Discovery agent	N.A.	Investigative	[27]
3-phenyl-4-hydroxyquinolin-2(1H)-one	DM2C9X8	Discovery agent	N.A.	Investigative	[16]
4,5,7-Trichloro-3-hydroxy-1H-quinolin-2-one	DMXZ9PI	Discovery agent	N.A.	Investigative	[28]
4,6-Dichloro-1H-indole-2-carboxylic acid	DM62XC3	Discovery agent	N.A.	Investigative	[29]
4-(3,4-Dihydro-1H-isoquinolin-2-yl)-quinoline	DMCOJIL	Discovery agent	N.A.	Investigative	[26]
4-Benzyl-1-(2-phenoxy-ethyl)-piperidine	DMQZ0D6	Discovery agent	N.A.	Investigative	[4]
4-Benzyl-1-phenethyl-piperidine hydrochloride	DMAI6X2	Discovery agent	N.A.	Investigative	[30]
4-Bromo-3-hydroxy-1H-quinolin-2-one	DMYOCFX	Discovery agent	N.A.	Investigative	[28]
4-Bromo-5,7-dichloro-3-hydroxy-1H-quinolin-2-one	DM2QJ5A	Discovery agent	N.A.	Investigative	[28]
4-Chloro-3-hydroxy-1H-quinolin-2-one	DMMALY3	Discovery agent	N.A.	Investigative	[28]
4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one	DMT3H2X	Discovery agent	N.A.	Investigative	[16]
4-[2-(3-Phenyl-propylamino)-ethyl]-phenol	DM64WSV	Discovery agent	N.A.	Investigative	[30]
4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol	DM74G6Q	Discovery agent	N.A.	Investigative	[4]
4-[2-(4-Phenyl-butoxy)-ethyl]-phenol	DML8B3T	Discovery agent	N.A.	Investigative	[30]
4-[2-(4-Phenyl-butylamino)-ethyl]-phenol	DMXLVJW	Discovery agent	N.A.	Investigative	[30]
4-[2-(4-Phenyl-piperidin-1-yl)-ethoxy]-phenol	DM8JM4Q	Discovery agent	N.A.	Investigative	[4]
4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol	DM5J7O8	Discovery agent	N.A.	Investigative	[30]
4-[2-(6-Phenyl-hexylamino)-ethyl]-phenol	DMLCIJX	Discovery agent	N.A.	Investigative	[30]
4-[3-(4-Phenyl-butylamino)-propyl]-phenol	DMOF9YN	Discovery agent	N.A.	Investigative	[31]
4-[3-(5-Phenyl-pentylamino)-propyl]-phenol	DMKDBHN	Discovery agent	N.A.	Investigative	[30]
4-{2-[Ethyl-(4-phenyl-butyl)-amino]-ethyl}-phenol	DMA21GM	Discovery agent	N.A.	Investigative	[30]
5,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione	DMUADN4	Discovery agent	N.A.	Investigative	[32]
5,7-Dichloro-4-hydroxy-3-phenyl-1H-quinolin-2-one	DMZJKIU	Discovery agent	N.A.	Investigative	[14]
5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione	DMG4UCX	Discovery agent	N.A.	Investigative	[14]
6,7-Dichloro-3-hydroxy-1H-quinazoline-2,4-dione	DMNEJ8W	Discovery agent	N.A.	Investigative	[32]
6-Chloro-1,4-dihydro-quinoxaline-2,3-dione	DMURJ34	Discovery agent	N.A.	Investigative	[33]
6-Methoxy-2-(4-phenoxy-benzyl)-1H-benzoimidazole	DMZP3XJ	Discovery agent	N.A.	Investigative	[24]
6-Nitro-1,4-dihydro-quinoxaline-2,3-dione	DM84CTA	Discovery agent	N.A.	Investigative	[33]
6-Nitro-2-(4-phenoxy-benzyl)-1H-benzoimidazole	DMZTXDV	Discovery agent	N.A.	Investigative	[24]
7-chloro-3-hydroxyquinazoline-2,4-dione	DM3OMLU	Discovery agent	N.A.	Investigative	[34]
8-Bromo-3-hydroxy-1H-benzo[b]azepine-2,5-dione	DMPVU7H	Discovery agent	N.A.	Investigative	[27]
8-Chloro-3-hydroxy-1H-benzo[b]azepine-2,5-dione	DM842L6	Discovery agent	N.A.	Investigative	[27]
8-Ethyl-3-hydroxy-1H-benzo[b]azepine-2,5-dione	DMY8W0K	Discovery agent	N.A.	Investigative	[27]
8-Fluoro-3-hydroxy-1H-benzo[b]azepine-2,5-dione	DMBZSAO	Discovery agent	N.A.	Investigative	[27]
Ala-Pro-Glu	DMTWB54	Discovery agent	N.A.	Investigative	[20]
AP-7	DMBU942	Discovery agent	N.A.	Investigative	[35]
Benzyl 4-aminobutyl(3-aminopropyl)carbamate	DMOKVAT	Discovery agent	N.A.	Investigative	[36]
CGP61594	DM8KFZH	Discovery agent	N.A.	Investigative	[15]
CN-2097	DMJA8I4	Neurological disorder	6B60	Investigative	[15]
Conantokin-G	DMC2IYH	Discovery agent	N.A.	Investigative	[37]
Conantokin-R	DMN4KJI	Discovery agent	N.A.	Investigative	[37]
Conantokins G	DMLHF3E	Discovery agent	N.A.	Investigative	[38]
Conantokins T	DMV6H5S	Discovery agent	N.A.	Investigative	[38]
d-AP5	DMY5OTN	Discovery agent	N.A.	Investigative	[15]
D-aspartic acid	DM7Z892	Discovery agent	N.A.	Investigative	[15]
d-CCPene	DM36D0F	Discovery agent	N.A.	Investigative	[15]
DNQX	DMQXPA5	Discovery agent	N.A.	Investigative	[39]
DQP-1105	DMQLJ3Y	Discovery agent	N.A.	Investigative	[40]
Gly-Amp-Glu	DMO8LAC	Discovery agent	N.A.	Investigative	[20]
Gly-b7Pro-Glu	DM8L09J	Discovery agent	N.A.	Investigative	[20]
Gly-Hyp-Glu	DM8XR4Y	Discovery agent	N.A.	Investigative	[20]
Gly-Pip-Glu	DMM0JA4	Discovery agent	N.A.	Investigative	[20]
H-Gly-D-dmP-Glu-OH	DMX2TGD	Discovery agent	N.A.	Investigative	[41]
H-Gly-dmP-Glu-OH	DMOYQPM	Discovery agent	N.A.	Investigative	[41]
homoquinolinic acid	DMBW5DU	Discovery agent	N.A.	Investigative	[15]
L-aspartic acid	DMWGPO6	N. A.	N. A.	Investigative	[15]
LY233053	DMC82DA	Discovery agent	N.A.	Investigative	[15]
N,N'-Bis-(4-butoxy-phenyl)-guanidine	DMLOP2B	Discovery agent	N.A.	Investigative	[22]
N,N'-Bis-(4-butyl-phenyl)-guanidine	DMOS2GH	Discovery agent	N.A.	Investigative	[22]
N,N'-Bis-(4-ethyl-phenyl)-guanidine	DM0CTG7	Discovery agent	N.A.	Investigative	[22]
N,N'-Bis-(4-hexyl-phenyl)-guanidine	DM0RQGU	Discovery agent	N.A.	Investigative	[22]
N,N'-Bis-(4-isopropyl-phenyl)-guanidine	DMM38BC	Discovery agent	N.A.	Investigative	[22]
N,N'-Bis-(4-sec-butyl-phenyl)-guanidine	DMFDXLB	Discovery agent	N.A.	Investigative	[22]
N-(2-methoxybenzyl)cinnamamidine	DM06S5Z	Discovery agent	N.A.	Investigative	[42]
N-(3-phenethoxybenzyl)-4-hydroxybenzamide	DMHZU8K	Discovery agent	N.A.	Investigative	[43]
N-(4-(benzyloxy)phenethyl)pyridin-4-amine	DMIPKNQ	Discovery agent	N.A.	Investigative	[44]
N1-dansyl-spermine	DM76CLF	Discovery agent	N.A.	Investigative	[15]
Nle-Pro-Glu	DM0FA6B	Discovery agent	N.A.	Investigative	[20]
NP93-31	DMMZXRT	Brain injury	NA07.Z	Investigative	[15]
NVP-AAM077	DM9DURZ	Discovery agent	N.A.	Investigative	[45]
Phe-Pro-Glu	DMJMLKA	Discovery agent	N.A.	Investigative	[20]
Phencyclidine	DMQBEYX	Discovery agent	N.A.	Investigative	[46]
Phenethyl-(3-phenyl-propyl)-amine	DMQWFO1	Discovery agent	N.A.	Investigative	[30]
Phenethyl-(4-phenyl-butyl)-amine	DMFQMHK	Discovery agent	N.A.	Investigative	[30]
Ro 63-1908	DMYVQF5	N. A.	N. A.	Investigative	[47]
RPR-118723	DMLDWCB	Discovery agent	N.A.	Investigative	[19]
Tenocyclidine	DMRM1QV	Discovery agent	N.A.	Investigative	[48]
TRANSTORINE	DMP4T87	Discovery agent	N.A.	Investigative	[29]
UBP141	DM6IG5J	Discovery agent	N.A.	Investigative	[21]
[3H]CGP39653	DMITR7A	Discovery agent	N.A.	Investigative	[15]
[3H]CGS19755	DM7H3JN	Discovery agent	N.A.	Investigative	[15]
[3H]CPP	DMR5UBF	Discovery agent	N.A.	Investigative	[15]
[3H]dizocilpine	DMEC2PF	Discovery agent	N.A.	Investigative	[15]
[3H]MDL105519	DMPKGHB	Discovery agent	N.A.	Investigative	[15]

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