General Information of DTT (ID: TTULVH8)

DTT Name Tyrosinase (TYR) DTT Info
Gene Name TYR

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
2 Approved Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [1]
Monobenzone DMVJS2K Vitiligo ED63.0 Approved [1]
------------------------------------------------------------------------------------
5 Clinical Trial Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
Melanoma vaccine DMQEC6Z Melanoma 2C30 Phase 3 [2]
Multi-epitope peptide melanoma vaccine DMZPEHY Melanoma 2C30 Phase 3 [3]
MKC-1106-MT DMXKOW6 Melanoma 2C30 Phase 2 [4]
Multi-epitope tyrosinase/gp100 vaccine DMN68ZL Melanoma 2C30 Phase 2 [5]
Polynoma-1 DM3QDA6 Melanoma 2C30 Phase 2 [6]
------------------------------------------------------------------------------------
135 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
3-(phenoxymethyl) benzylamine derivative 1 DM9YJWU Albinism EC23.2 Patented [7]
3-(phenoxymethyl) benzylamine derivative 2 DMGN9IX Albinism EC23.2 Patented [7]
3-(phenoxymethyl) benzylamine derivative 3 DM43EKN Albinism EC23.2 Patented [7]
3-(phenoxymethyl) benzylamine derivative 4 DM58X6N Albinism EC23.2 Patented [7]
3-(phenoxymethyl) benzylamine derivative 5 DM84HG2 Albinism EC23.2 Patented [7]
3-(phenoxymethyl) benzylamine derivative 6 DM0WBM3 Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 1 DMJ8X7A Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 2 DMYH4D1 Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 3 DML63B7 Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 4 DMKE5PB Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 5 DM4AM1E Albinism EC23.2 Patented [7]
Aromatic hydrazine carboxyimidoamide derivative 6 DM8HDQT Albinism EC23.2 Patented [7]
Benzimidazole derivative 3 DMY93WG Albinism EC23.2 Patented [7]
Benzimidazole derivative 4 DM9PL3F Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 1 DMND8R0 Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 2 DMUBG20 Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 3 DM42BU9 Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 4 DMNX5EU Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 5 DMNIZAR Albinism EC23.2 Patented [7]
Benzoic acid linked peptide analog 6 DMTHKES Albinism EC23.2 Patented [7]
Benzothiazole analog 1 DMHXFCQ Albinism EC23.2 Patented [7]
Benzothiazole analog 2 DMUKNXF Albinism EC23.2 Patented [7]
Benzothiazole analog 3 DMDLY38 Albinism EC23.2 Patented [7]
Benzothiazole analog 4 DMNDAT0 Albinism EC23.2 Patented [7]
Benzothiazole analog 5 DMN1J09 Albinism EC23.2 Patented [7]
Benzothiazoline derivative 1 DMJDC5T Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 1 DM79WI1 Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 10 DMRXMCH Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 11 DMVPR1D Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 12 DMOHBCN Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 13 DMKDBQG Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 14 DMWUAXM Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 2 DMAEQ0I Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 3 DMGV8T9 Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 4 DMNQF9S Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 5 DMBC48K Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 6 DMK9XV8 Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 7 DMES41R Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 8 DMRIPVG Albinism EC23.2 Patented [7]
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 9 DM7U20W Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 1 DMORFPT Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 2 DM6VPIR Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 3 DMVIZTY Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 4 DMLD49W Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 5 DMS68DP Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 6 DMSD2TN Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 7 DM2URPE Albinism EC23.2 Patented [7]
Cyclohexyl carbamate derivative 8 DMB9DEO Albinism EC23.2 Patented [7]
Diamine derivative 1 DMUG69Q Albinism EC23.2 Patented [7]
Diamine derivative 2 DMQEYTJ Albinism EC23.2 Patented [7]
Diamine derivative 3 DMSYX4U Albinism EC23.2 Patented [7]
Dihydroxyfumaric acid derivative 1 DMAH1EP Albinism EC23.2 Patented [7]
Monoamine derivative 1 DMRWNAY Albinism EC23.2 Patented [7]
Monoamine derivative 2 DMAZ6DI Albinism EC23.2 Patented [7]
Monoamine derivative 3 DM4I75L Albinism EC23.2 Patented [7]
Monoamine derivative 4 DMYFKP2 Albinism EC23.2 Patented [7]
Monoamine derivative 5 DM3PF60 Albinism EC23.2 Patented [7]
Nicotinyl hydroxamic acid derivative 1 DMW2LD5 Albinism EC23.2 Patented [7]
P-coumaric acid derivative 1 DM231WS Albinism EC23.2 Patented [7]
P-coumaric acid derivative 2 DMFTZBY Albinism EC23.2 Patented [7]
P-coumaric acid derivative 3 DMFE4IY Albinism EC23.2 Patented [7]
P-coumaric acid derivative 4 DM5WQP3 Albinism EC23.2 Patented [7]
P-coumaric acid derivative 5 DMFKGZ7 Albinism EC23.2 Patented [7]
P-coumaric acid derivative 6 DMF4YGC Albinism EC23.2 Patented [7]
PMID26815044-Compound-114 DMOJ936 Albinism EC23.2 Patented [7]
PMID26815044-Compound-115 DM8SWHO Albinism EC23.2 Patented [7]
PMID26815044-Compound-116 DMDUXRT Albinism EC23.2 Patented [7]
PMID26815044-Compound-117 DM2GON6 Albinism EC23.2 Patented [7]
PMID26815044-Compound-118 DMC28VB Albinism EC23.2 Patented [7]
PMID26815044-Compound-121 DMMNXA1 Albinism EC23.2 Patented [7]
PMID26815044-Compound-122 DM1HAGJ Albinism EC23.2 Patented [7]
PMID26815044-Compound-123 DMFTE3Y Albinism EC23.2 Patented [7]
PMID26815044-Compound-124 DM25WGP Albinism EC23.2 Patented [7]
PMID26815044-Compound-125 DM6EFIN Albinism EC23.2 Patented [7]
PMID26815044-Compound-126 DMMJK0L Albinism EC23.2 Patented [7]
PMID26815044-Compound-127 DMO97LR Albinism EC23.2 Patented [7]
PMID26815044-Compound-30 DMH8E7S Albinism EC23.2 Patented [7]
PMID26815044-Compound-31 DMBINQ9 Albinism EC23.2 Patented [7]
PMID26815044-Compound-32 DMN5H3C Albinism EC23.2 Patented [7]
PMID26815044-Compound-47 DMM3FJO Albinism EC23.2 Patented [7]
PMID26815044-Compound-48 DMJ1Z7U Albinism EC23.2 Patented [7]
PMID26815044-Compound-49 DMD9WRS Albinism EC23.2 Patented [7]
PMID26815044-Compound-50 DMYI1SX Albinism EC23.2 Patented [7]
PMID26815044-Compound-51 DMQGTJ5 Albinism EC23.2 Patented [7]
PMID26815044-Compound-52 DMN4C2O Albinism EC23.2 Patented [7]
PMID26815044-Compound-64 DMEKBOG Albinism EC23.2 Patented [7]
PMID26815044-Compound-93 DMV46DG Albinism EC23.2 Patented [7]
PMID26815044-Compound-H DMI3QLT Albinism EC23.2 Patented [7]
PMID26815044-Compound-I DMZISDR Albinism EC23.2 Patented [7]
PMID29130358-Compound-Figure11(3) DMSME2B N. A. N. A. Patented [8]
Polyhydroxy benzamide derivative 1 DMPHCJ5 Albinism EC23.2 Patented [7]
Polyhydroxy benzamide derivative 2 DM0BRNU Albinism EC23.2 Patented [7]
Polyhydroxy benzamide derivative 3 DMCLZWS Albinism EC23.2 Patented [7]
Polyhydroxy benzamide derivative 4 DM6QBV2 Albinism EC23.2 Patented [7]
Polyhydroxy benzamide derivative 5 DMZC6AI Albinism EC23.2 Patented [7]
Resorcinol compound 1 DMG4FYP Albinism EC23.2 Patented [7]
Resorcinol compound 10 DMPA26U Albinism EC23.2 Patented [7]
Resorcinol compound 11 DMGDLPZ Albinism EC23.2 Patented [7]
Resorcinol compound 12 DMEMT3I Albinism EC23.2 Patented [7]
Resorcinol compound 13 DMVARUE Albinism EC23.2 Patented [7]
Resorcinol compound 14 DM6XFA5 Albinism EC23.2 Patented [7]
Resorcinol compound 15 DMSLYVT Albinism EC23.2 Patented [7]
Resorcinol compound 16 DMFDXBJ Albinism EC23.2 Patented [7]
Resorcinol compound 17 DMFR4S0 Albinism EC23.2 Patented [7]
Resorcinol compound 18 DM64R2K Albinism EC23.2 Patented [7]
Resorcinol compound 19 DMJIZPQ Albinism EC23.2 Patented [7]
Resorcinol compound 2 DMGDQYW Albinism EC23.2 Patented [7]
Resorcinol compound 20 DME4OGJ Albinism EC23.2 Patented [7]
Resorcinol compound 21 DM8EQPJ Albinism EC23.2 Patented [7]
Resorcinol compound 22 DMSW3GB Albinism EC23.2 Patented [7]
Resorcinol compound 23 DMU3APC Albinism EC23.2 Patented [7]
Resorcinol compound 24 DM2IKDL Albinism EC23.2 Patented [7]
Resorcinol compound 25 DMEZUN7 Albinism EC23.2 Patented [7]
Resorcinol compound 26 DMT21JG Albinism EC23.2 Patented [7]
Resorcinol compound 27 DM71R3T Albinism EC23.2 Patented [7]
Resorcinol compound 28 DMCHLAN Albinism EC23.2 Patented [7]
Resorcinol compound 29 DML7ONU Albinism EC23.2 Patented [7]
Resorcinol compound 3 DMPTK0G Albinism EC23.2 Patented [7]
Resorcinol compound 30 DMMTVN4 Albinism EC23.2 Patented [7]
Resorcinol compound 31 DMSPCLD Albinism EC23.2 Patented [7]
Resorcinol compound 32 DM2RPYB Albinism EC23.2 Patented [7]
Resorcinol compound 33 DMLJYS1 Albinism EC23.2 Patented [7]
Resorcinol compound 34 DMQF90E Albinism EC23.2 Patented [7]
Resorcinol compound 4 DMIM9EY Albinism EC23.2 Patented [7]
Resorcinol compound 5 DMQ5TYK Albinism EC23.2 Patented [7]
Resorcinol compound 6 DM809YH Albinism EC23.2 Patented [7]
Resorcinol compound 7 DM031RU Albinism EC23.2 Patented [7]
Resorcinol compound 8 DMLF53V Albinism EC23.2 Patented [7]
Resorcinol compound 9 DMCJO0R Albinism EC23.2 Patented [7]
Thiazole derivative 1 DM2WDXV Albinism EC23.2 Patented [7]
Thiazolidine derivative 1 DM05VO6 Albinism EC23.2 Patented [7]
Thiazolidine derivative 2 DM73GNJ Albinism EC23.2 Patented [7]
Thiazolidine derivative 3 DMXFGTZ Albinism EC23.2 Patented [7]
Thiazoline derivative 1 DM86HU3 Albinism EC23.2 Patented [7]
Thiazoline derivative 2 DMXRE1V Albinism EC23.2 Patented [7]
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⏷ Show the Full List of 135 Patented Agent(s)
102 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
(+/-)-Daedalin A DMBSH5L Discovery agent N.A. Investigative [9]
1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl DMNDJTL Discovery agent N.A. Investigative [10]
1-(1,4-diacetylphenyl)dithiosemicarbazide DMHNOLA Discovery agent N.A. Investigative [11]
1-(1-(4-bromophenyl)ethylidene)thiosemicarbazide DMXJ58Z Discovery agent N.A. Investigative [11]
1-(1-(4-fluorophenyl)ethylidene)thiosemicarbazide DMQBHGK Discovery agent N.A. Investigative [11]
1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazide DM7WJOY Discovery agent N.A. Investigative [11]
1-(1-(pyridin-3-yl)ethylidene)thiosemicarbazide DMJ21XT Discovery agent N.A. Investigative [11]
1-(1-(thiophen-2-yl)ethylidene)thiosemicarbazide DMQSEF6 Discovery agent N.A. Investigative [11]
1-(1-p-tolylethylidene)thiosemicarbazide DM2PQFE Discovery agent N.A. Investigative [11]
1-(1-phenylethylidene)thiosemicarbazide DMN5SL6 Discovery agent N.A. Investigative [11]
1-(2,5-Dimethyl-1H-pyrrol-1-yl)thiourea DM3FHJK Discovery agent N.A. Investigative [12]
1-(3-Methylbutylidene)thiosemicarbazide DMI15LJ Discovery agent N.A. Investigative [12]
1-(3-Oxocyclohexylidene)thiosemicarbazide DMEMHIF Discovery agent N.A. Investigative [12]
1-(3-phenoxypropyl)-4-(piperidin-1-yl)piperidine DMG8DLM Discovery agent N.A. Investigative [10]
1-(3-Phenylallylidene)thiosemicarbazide DMFPUGV Discovery agent N.A. Investigative [12]
1-(4-(benzyloxy)phenyl)-3-hydroxyurea DM7FWK8 Discovery agent N.A. Investigative [13]
1-(4-bromophenyl)-3-hydroxyurea DMEUHDL Discovery agent N.A. Investigative [13]
1-(4-Methylpent-3-en-2-ylidene)thiosemicarbazide DM3NVLB Discovery agent N.A. Investigative [12]
1-(But-2-enylidene)thiosemicarbazide DMEULBF Discovery agent N.A. Investigative [12]
1-(Butan-2-ylidene)thiosemicarbazide DMXU1EF Discovery agent N.A. Investigative [12]
1-(Propan-2-ylidene)thiosemicarbazide DMO10FD Discovery agent N.A. Investigative [12]
1-Cyclohexylidenethiosemicarbazide DM7A50Z Discovery agent N.A. Investigative [12]
1-Cyclopentylidenethiosemicarbazide DMDGWAY Discovery agent N.A. Investigative [12]
1-Ethylidenethiosemicarbazide DMQRKZO Discovery agent N.A. Investigative [12]
1-hydroxy-3-(4-(trifluoromethyl)phenyl)urea DMGNVEF Discovery agent N.A. Investigative [13]
1-hydroxy-3-(4-nitrophenyl)urea DMZ7GUP Discovery agent N.A. Investigative [13]
1-hydroxy-3-phenylurea DM4TSVC Discovery agent N.A. Investigative [13]
1-Propylidenethiosemicarbazide DMXOUFI Discovery agent N.A. Investigative [12]
2,2',4,4',6'-pentahydroxychalcone DMAYXUR Discovery agent N.A. Investigative [14]
2,2',4,4'-tetrahydroxy-6'-methoxychalcone DMMJ613 Discovery agent N.A. Investigative [14]
2,2',4,4'-tetrahydroxychalcone DMM6KBD Discovery agent N.A. Investigative [14]
2,2'-bi(1,3,4-thiadiazole)-5,5'(4H,4'H)-dithione DMPMOHQ Discovery agent N.A. Investigative [15]
2,4,3',5'-tetrahydroxybibenzyl DMI2PY7 Discovery agent N.A. Investigative [16]
2-(butylthiomethyl)-5-hydroxy-4H-pyran-4-one DMFO7CH Discovery agent N.A. Investigative [17]
2-(cyclohexylthiomethyl)-5-hydroxy-4H-pyran-4-one DM2CAI1 Discovery agent N.A. Investigative [17]
2-(ethylthiomethyl)-5-hydroxy-4H-pyran-4-one DM8GJCU Discovery agent N.A. Investigative [17]
2-(heptylthiomethyl)-5-hydroxy-4H-pyran-4-one DM490BL Discovery agent N.A. Investigative [17]
2-(hexylthiomethyl)-5-hydroxy-4H-pyran-4-one DM235Q4 Discovery agent N.A. Investigative [17]
2-hydroxy-3-isopropyl-2,4,6-cycloheptatrien-1-one DMK8WUR Discovery agent N.A. Investigative [18]
2-hydroxy-5-isopropyl-2,4,6-cycloheptatrien-1-one DMSDYZQ Discovery agent N.A. Investigative [18]
2-hydroxyphenethyl 3,4,5-trihydroxybenzoate DMHK2NQ Discovery agent N.A. Investigative [19]
3,4-dihydroxybenzaldehyde-O-ethyloxime DMZJ4VL Discovery agent N.A. Investigative [20]
3-(2,4-dihydroxyphenyl)propionic acid DMXQROU Discovery agent N.A. Investigative [21]
3-hydroxyphenethyl 3,4,5-trihydroxybenzoate DMMAK83 Discovery agent N.A. Investigative [19]
3hydroxy-1-methyl-1-phenylurea DM4758S Discovery agent N.A. Investigative [13]
4',4-Dihydroxychalcone DMFPO16 Discovery agent N.A. Investigative [22]
4'-(4-Aminobenzensulfonamide)-4-hydroxychalcone DMGOTYC Discovery agent N.A. Investigative [22]
4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone DMA6E28 Discovery agent N.A. Investigative [22]
4'-(4-Nitrobenzensulfonamide)-4-hydroxychalcone DMHB1N6 Discovery agent N.A. Investigative [22]
4'-(Benzensulfonamide)-4-hydroxychalcone DML2EF4 Discovery agent N.A. Investigative [22]
4'-(p-Toluenesulfonamide)-4-hydroxychalcone DMRFWE1 Discovery agent N.A. Investigative [22]
4'-Amino-4-hydroxychalcone DM9S5V0 Discovery agent N.A. Investigative [22]
4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol DM1NVEI Discovery agent N.A. Investigative [23]
4-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol DM4SPV7 Discovery agent N.A. Investigative [24]
4-adamantyl resorcinol DME24LV Discovery agent N.A. Investigative [25]
4-hexyl resorcinol DM36JUD Discovery agent N.A. Investigative [26]
4-hydroxyphenethyl 3,4,5-trihydroxybenzoate DMJ7G0E Discovery agent N.A. Investigative [19]
5,5'-methylenebis(1,3,4-oxadiazole-2(3H)-thione) DMPVBC2 Discovery agent N.A. Investigative [15]
5,5'-methylenebis(1,3,4-thiadiazole-2(3H)-thione) DMW13SO Discovery agent N.A. Investigative [15]
5-(3-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione DM2H9ND Discovery agent N.A. Investigative [15]
5-(4-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione DMB2GLE Discovery agent N.A. Investigative [15]
5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol DMIB9AX Discovery agent N.A. Investigative [27]
5-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol DMJRBKO Discovery agent N.A. Investigative [24]
5-(pyridin-4-yl)-1,3,4-oxadiazole-2(3H)-thione DM93MAX Discovery agent N.A. Investigative [15]
5-(pyridin-4-yl)-1,3,4-thiadiazole-2(3H)-thione DMEL8XU Discovery agent N.A. Investigative [15]
5-benzhydryl-1,3,4-oxadiazole-2(3H)-thione DM65WZ7 Discovery agent N.A. Investigative [15]
5-benzhydryl-1,3,4-thiadiazole-2(3H)-thione DMBQ5HV Discovery agent N.A. Investigative [15]
5-benzyl-1,3,4-oxadiazole-2(3H)-thione DM8QK2O Discovery agent N.A. Investigative [15]
5-cyclohexyl-1,3,4-oxadiazole-2(3H)-thione DMMYENH Discovery agent N.A. Investigative [15]
5-hydroxy-2-(pentylthiomethyl)-4H-pyran-4-one DMTO2L3 Discovery agent N.A. Investigative [17]
5-hydroxy-2-(propylthiomethyl)-4H-pyran-4-one DM7M1RZ Discovery agent N.A. Investigative [17]
5-phenyl-1,3,4-oxadiazole-2(3H)-thione DMZ6TRV Discovery agent N.A. Investigative [15]
5-phenyl-1,3,4-thiadiazole-2(3H)-thione DMCKBQY Discovery agent N.A. Investigative [15]
5-{8(Z),-pentadecenyl}resorcinol DMNRWEV Discovery agent N.A. Investigative [28]
5-{8(Z),11(Z),14-pentadecatrienyl}resorcinol DMSZ3T6 Discovery agent N.A. Investigative [28]
5-{8(Z),11(Z)-pentadecadienyl}resorcinol DM0EBWR Discovery agent N.A. Investigative [28]
6-(3-Hydroxy-phenyl)-naphthalen-2-ol DMH8WA2 Discovery agent N.A. Investigative [24]
7,3',4'-trihydroxyisoflavone DM5JV8G Discovery agent N.A. Investigative [29]
7,8,4'-trihydroxyisoflavone DM80GFL Discovery agent N.A. Investigative [29]
7-(3,5-dihydroxyphenyl)naphthalene-1,3-diol DM9BS5L Discovery agent N.A. Investigative [24]
ASKENDOSIDE B DMTBZUC Discovery agent N.A. Investigative [30]
Broussonin C DMKM9F0 Discovery agent N.A. Investigative [31]
Crocusatin-K DMELUG5 Discovery agent N.A. Investigative [32]
DAEDALIN A DMWR3XL Discovery agent N.A. Investigative [9]
ETHISTERONE DMDXRP1 Discovery agent N.A. Investigative [33]
HINOKITIOL DMHL9Y6 Discovery agent N.A. Investigative [18]
Kazinol C DMS527J Discovery agent N.A. Investigative [31]
Kazinol F DMFVT81 Discovery agent N.A. Investigative [31]
KAZINOL S DMEV2AL Discovery agent N.A. Investigative [31]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [34]
Kojic acid-phenylalanine amide DMRB1AT Discovery agent N.A. Investigative [35]
N-(2,4-dihydroxybenzyl)-3,4,5-trihydroxybenzamide DMNT3JV Discovery agent N.A. Investigative [36]
N-(2,4-dihydroxybenzyl)-3,4-dihydroxybenzamide DM3IMXF Discovery agent N.A. Investigative [36]
N-(2,4-dihydroxybenzyl)-3,5-dihydroxybenzamide DM6U8SL Discovery agent N.A. Investigative [36]
N-butylresorcinol DM8STQA Discovery agent N.A. Investigative [25]
OXYRESVERATROL DMN7S4L Discovery agent N.A. Investigative [16]
PHENYLTHIOUREA DMM1IAU Discovery agent N.A. Investigative [13]
ROSMARINIC ACID DMQ6SJT Rheumatoid arthritis FA20 Investigative [34]
S-2-(o-toluidino)-2-oxoethyl carbamothioate DMU9F7K Discovery agent N.A. Investigative [37]
SODIUM ZINC DIHYDROLIPOYLHISTIDINATE DMEZAPR Discovery agent N.A. Investigative [38]
SRI-224 DM35NF6 Discovery agent N.A. Investigative [20]
TROPOLONE DMOMXP7 Discovery agent N.A. Investigative [20]
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⏷ Show the Full List of 102 Investigative Drug(s)
Molecule Interaction Atlas

References

1 Identification of an Alkylhydroquinone from Rhus succedanea as an Inhibitor of Tyrosinase and Melanogenesis. J Agric Food Chem. 2009 Mar 25;57(6):2200-5.
2 National Cancer Institute Drug Dictionary (drug id 685201).
3 Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in-adjuvant with PF-3512676 and GM-CSF in metastatic melanoma. Correction in: volume 35 on page 650.
4 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
5 ClinicalTrials.gov (NCT00003362) Vaccine Therapy Plus Immune Adjuvants in Treating Patients With Advanced Melanoma. U.S. National Institutes of Health.
6 An immuno-oncology company developing a novel polyvalent antigen therapy for the treatment of melanoma. Polynoma. 2015.
7 Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62.
8 Gelatinase inhibitors: a patent review (2011-2017).Expert Opin Ther Pat. 2018 Jan;28(1):31-46.
9 Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1063-4.
10 Dragon method for finding novel tyrosinase inhibitors: Biosilico identification and experimental in vitro assays. Eur J Med Chem. 2007 Nov-Dec;42(11-12):1370-81.
11 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102.
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13 Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10.
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29 Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1162-4.
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