Details of the Drug-Related molecule(s) Interaction Atlas

Cephaeline Drug Info

Cephaeline; Cephaelin; 483-17-0; 7',10,11-Trimethoxyemetan-6'-ol; UNII-QA971541A1; Desmethylemetine; QA971541A1; Dihydropsychotrine; Cepheline; GNF-Pf-307; (1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol; NSC32944; Cephaelinel; (-)-Cephaeline; EINECS 207-591-6; Prestwick2_000428; Prestwick3_000428; Prestwick1_000428; Prestwick0_000428; AC1L9CF2; BSPBio_000416; SCHEMBL181711; SPBio_002355; CHEMBL255708

Cross-matching ID

PubChem CID

442195

ChEBI ID

CHEBI:3533

CAS Number

CAS 483-17-0

TTD Drug ID

DM1ZFCS

VARIDT Drug ID

DR01645

General Information of Drug (ID: DM1ZFCS)

Molecule-Related Drug Atlas

Molecule Type:

DTP

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Transported By P-glycoprotein 1 (ABCB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amoxicillin	DMUYNEI	Acute otitis media	AB00	Approved	[3]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[4]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[5]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[6]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[5]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[5]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[7]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[5]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[8]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[9]
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Drug(s) Affected By Interleukin-6 receptor subunit alpha (IL6R)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
TECFIDERA	DM2OVDT	Multiple sclerosis	8A40	Approved	[10]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[11]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[12]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[13]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[14]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[15]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[16]
Emetine	DMCT2YF	Hepatitis virus infection	1E50-1E51	Approved	[2]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[17]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[18]
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Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[19]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[20]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[21]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[22]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[23]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[24]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[25]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[26]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[27]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[25]
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Drug(s) Affected By C-C motif chemokine 4 (CCL4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[28]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[29]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[30]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[31]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[32]
Betamethasone	DMAHJEF	Acute adrenal insufficiency		Approved	[2]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[33]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[34]
Emetine	DMCT2YF	Hepatitis virus infection	1E50-1E51	Approved	[2]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[35]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[36]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[37]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[38]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[39]
Imiquimod	DM1TMA3	Alopecia areata	ED70.2	Approved	[40]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[41]
TECFIDERA	DM2OVDT	Multiple sclerosis	8A40	Approved	[42]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[43]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[44]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[45]
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Drug(s) Affected By C-C motif chemokine 5 (CCL5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[46]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[47]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[48]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[43]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[49]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[50]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[30]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[51]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[31]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[52]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Gene/Protein Processing	[2]
C-C motif chemokine 4 (CCL4)	OT6B8P25	CCL4_HUMAN	Gene/Protein Processing	[2]
C-C motif chemokine 5 (CCL5)	OTSCA5CK	CCL5_HUMAN	Gene/Protein Processing	[2]
Interleukin-6 receptor subunit alpha (IL6R)	OTCQL07Z	IL6RA_HUMAN	Gene/Protein Processing	[2]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Gene/Protein Processing	[2]
Vascular endothelial growth factor A, long form	OTIM9MZ3	VEGFA_HUMAN	Gene/Protein Processing	[2]

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