Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM9UB0P)

Drug Name
Oxaprozin Drug Info
Synonyms
Actirin; Alvo; Danoprox; Daypro; Dayrun; Deflam; Oxaprozina; Oxaprozine; Oxaprozinum; Voir; Xopane; Apotex brand of oxaprozin; CSC brand of oxaprozin; Pfizer brand of oxaprozin; Rhoxalpharma brand of oxaprozin; TRB brand of oxaprozin; Lyl)propenoic acid; NCI310839; O 9637; WY 21743; Apo-Oxaprozin; Daypro (TN); Duraprox (TN); Oxaprozina [INN-Spanish]; Oxaprozine [INN-French]; Oxaprozinum [INN-Latin]; Rhoxal-oxaprozin; WY-21743; WY-21,743; Oxaprozin (JP15/USAN/INN); Oxaprozin [USAN:BAN:INN:JAN]; Beta-(4,5-Diphenyloxazol-2-yl)propionic acid; 3-(4, 5-Diphenyl-2-oxazo; 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid; 3-(4,5-Diphenyl-2-oxazolyl)propenoic acid; 4, 5-Diphenyl-2-oxazolepropionic acid; 4,5-Diphenyl-2-oxazolepropanoic acid; 4,5-Diphenyl-2-oxazolepropionic acid
Indication
Disease Entry ICD 11 Status REF
Osteoarthritis FA00-FA05 Approved [1]
Rheumatoid arthritis FA20 Approved [2]
Therapeutic Class
Antiinflammatory Agents
Cross-matching ID
PubChem CID
4614
ChEBI ID
CHEBI:7822
CAS Number
CAS 21256-18-8
TTD Drug ID
DM9UB0P
INTEDE Drug ID
DR1212
ACDINA Drug ID
D00498

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostaglandin G/H synthase (COX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [9]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [10]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [11]
Dexibuprofen DMFYBD0 Ankylosing spondylitis FA92.0 Approved [12]
Ketorolac DMI4EL5 Postoperative inflammation 1A00-CA43.1 Approved [13]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [14]
Aceclofenac DMZDF0B Inflammation 1A00-CA43.1 Approved [15]
Lornoxicam DMYZFXN Migraine 8A80 Approved [16]
Morniflumate DM9UTDE Otitis media AA80-AB0Z Approved [17]
Nepafenac DMYK490 Osteoarthritis FA00-FA05 Approved [18]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [19]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [20]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [21]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [22]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [24]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [25]
Estrone DM5T6US Acne vulgaris ED80 Approved [26]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [27]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 16 (NGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [28]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [31]
Panobinostat DM58WKG Chronic graft versus host disease Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [33]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [33]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
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Drug(s) Affected By HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [37]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [7]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [7]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [38]
Allopurinol DMLPAOB Gout FA25 Approved [39]
Ticlopidine DMO946V Acute coronary syndrome BA41 Approved [40]
Selenium DM25CGV N. A. N. A. Approved [41]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [7]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [43]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [49]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [52]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [53]
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Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [54]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [6]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [56]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [6]
Ethacrynic acid DM60QMR Edema MG29 Approved [6]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [6]
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Drug(s) Affected By Cytochrome P450 4A11 (CYP4A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [58]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [5]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [5]
Methotrexate DM2TEOL Anterior urethra cancer Approved [59]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [60]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [61]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [5]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [5]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin G/H synthase (COX) TTK0943 PGH1_HUMAN; PGH2_HUMAN Inhibitor [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C9 (CYP2C9) Main DME DE5IED8 CP2C9_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 4A11 (CYP4A11) OTPU5J0S CP4AB_HUMAN Gene/Protein Processing [5]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Gene/Protein Processing [6]
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1) OTVVI3UI DQB1_HUMAN Gene/Protein Processing [7]
Peroxisome proliferator-activated receptor gamma (PPARG) OTHMARHO PPARG_HUMAN Gene/Protein Processing [8]
Tumor necrosis factor receptor superfamily member 16 (NGFR) OTPKSM49 TNR16_HUMAN Gene/Protein Processing [3]

References

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