Details of the Drug-Related molecule(s) Interaction Atlas

Aniline Drug Info

ANILINE; Aminobenzene; Aminophen; Anilin; Anilin [Czech]; Anilina; Anilina [Italian, Polish]; Aniline (and salts); Aniline and homologs; Aniline and homologues; Aniline oil; Aniline reagent; Anyvim; Arylamine; Benzenamine; Benzene, amino; Benzeneamine; Benzidam; Blue Oil; Cyanol; Krystallin; Kyanol; Phenylamine; RCRA waste no. U012; Rcra waste number U012; UN 1547; 62-53-3; C.I. 76000; C.I. Oxidation Base 1; CCRIS 44; CI Oxidation Base 1; Caswell No. 051C; HSDB 43; Huile D'aniline; Huile d'aniline [French]; NCI-C03736; UNII-SIR7XX2F1K

Cross-matching ID

PubChem CID

6115

ChEBI ID

CHEMBL17296

CAS Number

CAS 62-53-3

TTD Drug ID

DMLCAR9

INTEDE Drug ID

DR2317

General Information of Drug (ID: DMLCAR9)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

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Drug(s) Metabolized By Cytochrome P450 102A1 (cyp102)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[2]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[7]
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[8]
Dextromethorphan	DMUDJZM	Allergic rhinitis	CA08.0	Approved	[2]
Nifedipine	DMSVOZT	Angina pectoris	BA40	Approved	[1]
Chlorzoxazone	DMCYVDT	Acute pain	MG31	Approved	[1]
Amodiaquine	DME4RA8	Malaria	1F40-1F45	Approved	[2]
Buspirone	DMBS632	Anxiety disorder	6B00-6B0Z	Approved	[2]
Mefenamic acid	DMK7HFI	Dysmenorrhea	GA34.3	Approved	[7]
Meclofenamic acid	DM05FXR	Ankylosing spondylitis	FA92.0	Approved	[7]
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Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[9]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[10]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[11]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[12]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[13]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[14]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[15]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[16]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[17]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[18]
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Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[19]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[20]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[21]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[22]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[23]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[24]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[25]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[26]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[27]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[25]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[28]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[29]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[30]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[31]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[32]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[33]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[34]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[35]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[36]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[37]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[38]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[39]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[35]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[40]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[41]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[42]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[44]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[45]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[46]
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Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Procainamide	DMNMXR8	Ventricular arrhythmias	BC71	Approved	[47]
Hydralazine	DMU8JGH	Chronic heart failure	BD1Z	Approved	[4]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[48]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[49]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[50]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[51]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[52]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[53]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[54]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[55]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 102A1 (cyp102)^{Main DME}	DE4OGUF	CPXB_BACMB	Substrate	[1] , [2]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[3]
Arylamine N-acetyltransferase 2 (NAT2)	OTBPDQOY	ARY2_HUMAN	Biotransformations	[4]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Gene/Protein Processing	[5]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Gene/Protein Processing	[5]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Gene/Protein Processing	[6]

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