Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRH291)

Drug Name
Dexanabinol Drug Info
Synonyms
Sinnabidiol; HU 211; HU-211; PRS 211007-000; (6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol; 1,1-Dimethylheptyl-11-hydroxytetrahydrocannabinol; 1,1-Dimethylheptyl-7-hydroxy-delta(6)-tetrahydrocannabinol; 11-Hydroxy-delta(8)-tetrahydrocannabinol-dimethylheptyl; 11-Hydroxy-delta-8-dmh-thc; 11-Hydroxymethyl-delta(8)-tetrahydrocannabinol-dimethylheptyl; 11-OH-delta(8)-Thc-dmh; 5'(1,1-Dimethylheptyl)-7-hydroxyhexahydrocannabinol; 7-Hydroxy-delta-6-tetrahydrocannabinoldimethylheptyl
Indication
Disease Entry ICD 11 Status REF
Traumatic brain injury NA07.Z Phase 3 [1]
Cross-matching ID
PubChem CID
107778
CAS Number
CAS 112924-45-5
TTD Drug ID
DMRH291

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting N-methyl-D-aspartate receptor (NMDAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [3]
Cycloserine DMT1I52 Bacterial infection 1A00-1C4Z Approved [4]
Benzphetamine DMIJATC Obesity 5B81 Approved [5]
Ketamine DMT5HA4 Anaesthesia 9A78.6 Approved [6]
Felbamate DM1V5ZS Epilepsy 8A60-8A68 Approved [7]
Memantine DMD9WSC Alzheimer disease 8A20 Approved [8]
Huperzine A DMMAWLU Alzheimer disease 8A20 Approved [9]
Levorphanol DMGS80V Pain MG30-MG3Z Approved [10]
Magnesium Sulfate DMVEK07 Acute pain MG31 Approved [11]
Magnesium DMU4ORS Ischemic stroke 8B11.5Z Approved [12]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [14]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [15]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [16]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [14]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [14]
Quercetin DM3NC4M Obesity 5B81 Approved [17]
Fluoxetine DM3PD2C Bipolar depression Approved [14]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [15]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Gefitinib DM15F0X Colon adenocarcinoma Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [22]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [23]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [22]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [24]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [28]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [29]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [30]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [31]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [33]
Gefitinib DM15F0X Colon adenocarcinoma Approved [34]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [28]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [38]
Paclitaxel DMLB81S Breast carcinoma Approved [39]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [40]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [41]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [30]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [31]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [43]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [44]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [45]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [46]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [47]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [48]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [49]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [51]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [52]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Gefitinib DM15F0X Colon adenocarcinoma Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Selenium DM25CGV N. A. N. A. Approved [56]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [57]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [59]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [60]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [62]
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Drug(s) Affected By Cannabinoid receptor 1 (CNR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Menthol DMG2KW7 Back pain ME84.Z Approved [66]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [67]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [68]
Norepinephrine DMOUC09 Alopecia ED70 Approved [69]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [70]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [71]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
N-methyl-D-aspartate receptor (NMDAR) TT9IK2Z NOUNIPROTAC Antagonist [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cannabinoid receptor 1 (CNR1) OTEALO6G CNR1_HUMAN Drug Response [2]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Post-Translational Modifications [2]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [2]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [2]
Nuclear protein 1 (NUPR1) OT4FU8C0 NUPR1_HUMAN Gene/Protein Processing [2]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Protein Interaction/Cellular Processes [2]

References

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