Details of the Drug

General Information of Drug (ID: DMLB81S)

• Drug Name: Paclitaxel
• Synonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-b; 7-epi-Paclitaxel; ABI-007; Abraxane; Capxol; Ebetaxel; EmPAC; Genaxol; Genetaxyl; Genexol; Intaxel; LipoPac; OncoGel; Onxol; Paclitaxel (Taxol); Paxceed; Paxene; Plaxicel; TAXOL; TaxAlbin; Taxol A; Xorane; Yewtaxan; Zisu; nab-paclitaxel; paclitaxel

Indication

Disease Entry	ICD 11	Status	REF
Breast carcinoma	N.A.	Approved	[1]
Cutaneous melanoma	2C30	Approved	[1]
Cutaneous squamous cell carcinoma	2C30	Approved	[1]
Epithelial ovarian cancer	2B5D	Approved	[1]
Extragonadal germ cell tumor	N.A.	Approved	[1]
Fallopian tube neoplasm	N.A.	Approved	[1]
Gastroesophageal junction adenocarcinoma	2B71	Approved	[1]
Inflammatory breast cancer	2C62	Approved	[1]
Kaposi sarcoma	2B57	Approved	[1]
Lung adenocarcinoma	N.A.	Approved	[1]
Lung cancer	2C25.0	Approved	[1]
Non-small-cell lung cancer	2C25.Y	Approved	[1]
Ocular hypertension	9C61.01	Approved	[1]
Ovarian neoplasm	N.A.	Approved	[1]
Ovarian serous cystadenocarcinoma	N.A.	Approved	[1]
Pain	MG30-MG3Z	Approved	[1]
Pancreatic ductal carcinoma	2C10.0	Approved	[1]
Primary peritoneal carcinoma	N.A.	Approved	[1]
Testicular germ cell tumor	N.A.	Approved	[1]
Urethral cancer	2C93	Approved	[1]
Lung large cell carcinoma	N.A.	Investigative	[1]

• Therapeutic Class: Anticancer Agents
• ATC Code:
  L01CD01: Paclitaxel
  L01CD: Taxanes
  L01C: PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
  L01: ANTINEOPLASTIC AGENTS
  L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 3:
  Molecular Weight (mw); 853.918
  Logarithm of the Partition Coefficient (xlogp); 2.5
  Rotatable Bond Count (rotbonds); 14
  Hydrogen Bond Donor Count (hbonddonor); 4
  Hydrogen Bond Acceptor Count (hbondacc); 14
• ADMET Property:
  BDDCS Class: Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 2: low solubility and high permeability [2]
  Clearance: The drug present in the plasma can be removed from the body at the rate of 6.4 mL/min/kg [3]
  Elimination: 5% of drug is excreted from urine in the unchanged form [2]
  Half-life: The concentration or amount of drug in body reduced by one-half in 24 hours [3]
  Metabolism: The drug is metabolized via the hepatic []
  MRTD: The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 5.5391 micromolar/kg/day [4]
  Unbound Fraction: The unbound fraction of drug in plasma is 0.12% [3]
  Vd: Fluid volume that would be required to contain the amount of drug present in the body at the same concentration as in the plasma 3 L/kg [3]

Adverse Drug Reaction (ADR)

ADR Term	Variation	Related DOT	DOT ID	REF
Apoptosis	Not Available	SOD2	OT08HOR5	[5]
Apoptosis	Not Available	MOS	OTNMQPFJ	[5]
Apoptosis	Not Available	NFKB1	OTNRRD8I	[5]
Apoptosis	Not Available	DAD1	OTUUNQBT	[5]
Cytogenetic abnormality	Not Available	PLK2	OTKMJXJ8	[5]
Mitochondrial toxicity	Not Available	PARP1	OTIESHK4	[5]
Vascular disorders	Not Available	ALPL	OTG7J4BP	[5]
Vascular disorders	Not Available	VWF	OTNMMA2P	[5]
Vascular disorders	Not Available	LPL	OTTW0267	[5]

• Chemical Identifiers:
  Formula: C47H51NO14
  IUPAC Name: [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
  Canonical SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
  InChI: InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1
  InChIKey: RCINICONZNJXQF-MZXODVADSA-N
• Cross-matching ID:
  PubChem CID: 36314
  ChEBI ID: ChEBI:45863
  CAS Number: 33069-62-4
  UNII: B3C86E80A0
  DrugBank ID: DB17223
  VARIDT ID: DR00342
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Multidrug resistance protein 3 (ABCB4)	DTZRMK5	MDR3_HUMAN	Substrate	[6]
TAP-like protein (ABCB9)	DT68UV2	ABCB9_HUMAN	Substrate	[7]
Multidrug resistance-associated protein 7 (ABCC10)	DTPS120	MRP7_HUMAN	Substrate	[8]
Organic anion transporter 2 (SLC22A7)	DT0OC1Q	S22A7_HUMAN	Substrate	[9]
Multidrug resistance-associated protein 3 (ABCC3)	DTQ3ZHF	MRP3_HUMAN	Substrate	[10]
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[11]
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[12]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[13]
Organic anion transporting polypeptide 1B1 (SLCO1B1)	DT3D8F0	SO1B1_HUMAN	Substrate	[14]
Organic anion transporting polypeptide 1B3 (SLCO1B3)	DT9C1TS	SO1B3_HUMAN	Substrate	[15]
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[16]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1)	OTJISZOX	PLCE1_HUMAN	Drug Response	[17]
14-3-3 protein theta	OTWG7F3H	1433T_HUMAN	Gene/Protein Processing	[18]
3-phosphoinositide-dependent protein kinase 1 (PDPK1)	OTT09ZVP	PDPK1_HUMAN	Drug Response	[19]
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1)	OTNWHUJ1	AL9A1_HUMAN	Gene/Protein Processing	[20]
Abnormal spindle-like microcephaly-associated protein (ASPM)	OTKXQMNA	ASPM_HUMAN	Gene/Protein Processing	[21]
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A)	OTRHPFO2	AN32A_HUMAN	Drug Response	[22]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Gene/Protein Processing	[23]
Activated RNA polymerase II transcriptional coactivator p15 (SUB1)	OTK71JYU	TCP4_HUMAN	Gene/Protein Processing	[20]
Acyl-coenzyme A thioesterase 8 (ACOT8)	OTHY684G	ACOT8_HUMAN	Gene/Protein Processing	[24]
Adenylate cyclase type 6 (ADCY6)	OTFOY4WW	ADCY6_HUMAN	Gene/Protein Processing	[25]

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC2	0.4175	4.7547	-8.0395	0.5425
TC71	CTRP2	-10.3478	-8.7191	-10.3478	99.2885
SK-N-MC	CTRP2	-9.701	-7.3338	-9.701	97.0639
A-673	GDSC2; CTRP2; CCLE	-8.294	-6.8342	-8.294	63.2949
MHH-ES-1	GDSC2; CTRP2; CCLE	-8.1267	-5.3033	-8.1268	62.5489
EW-1	GDSC1; GDSC2	-7.7372	-6.0007	-7.7429	33.423
SK-PN-DW	GDSC1; GDSC2	-7.6498	-5.3975	-7.6785	32.8529
SK-ES-1	GDSC1; GDSC2; CTRP2; CCLE	-7.6417	-4.0871	-7.6424	60.3893
ES8	GDSC1; GDSC2	-7.4668	-6.433	-7.467	31.3725
ES4	GDSC1; GDSC2	-7.379	-3.2834	-7.7539	32.0919
HOS	GDSC2; CTRP2; CCLE	-7.2078	1.6757	-7.5018	57.4961
NY	GDSC2	-7.1024	-3.9845	-8.3727	12.3387
EW-16	GDSC1; GDSC2	-7.0903	-5.0804	-7.1185	28.6523
HuO9	GDSC2	-6.791	-4.9341	-7.6242	6.6484
SaOS-2	GDSC2; CTRP2; CCLE	-6.7883	-3.767	-6.7885	56.6439
EW-22	GDSC2	-6.4579	-3.7013	-7.9632	7.824
SW1353	CTRP2; CCLE	-6.3999	1.609	-6.6323	73.933
CAL-72	GDSC2	-6.3627	-1.9326	-8.7695	12.5375
NOS-1 [Human HNSCC]	GDSC1; GDSC2	-6.3361	-2.7252	-6.7835	24.6534
EW-7	GDSC2	-6.3091	-3.1198	-8.1352	8.5009
ES1	GDSC1; GDSC2	-6.2911	-3.9238	-6.4162	23.0286
SJSA-1	GDSC1; GDSC2; CTRP2; CCLE	-5.7005	-2.674	-5.7016	49.6229
TC-71	GDSC1; GDSC2; CCLE	-4.9606	-2.3192	-4.9638	40.6048
U2OS	GDSC2; CTRP2; CCLE	-4.8698	-0.2995	-4.8916	48.1952
CHSA0011	GDSC2	-4.1058	1.3515	-6.3402	20.9072
EW-24	GDSC1; GDSC2	-3.7808	-0.0511	-5.3333	10.8105
ES6	GDSC1; GDSC2	-3.4731	3.3469	-6.7607	16.5208
EW-3	GDSC1; GDSC2	-3.2758	0.7101	-5.2767	9.3856
EW-18	GDSC1; GDSC2	-2.733	3.0558	-6.0098	11.6342
MG-63	GDSC2; CTRP2; CCLE	-2.3433	18.6942	-8.1443	43.15
G-292 clone A141B1	GDSC2; CTRP2	-2.1312	12.166	-5.0636	40.3378
U-CH2	GDSC2	-1.1103	7.2927	-6.9182	15.5298
CADO-ES1	GDSC2	-0.0786	2.0532	-7.3169	0.0112
H-EMC-SS	GDSC1; GDSC2	0.167	2.62	-4.0866	0.3713
CHSA0108	GDSC2	0.1737	11.5484	-8.0841	17.6547
HuO-3N1	GDSC2	0.2755	3.4204	-7.6416	0.1136
EW-13	GDSC1; GDSC2	0.2986	2.7961	-4.0996	0.3562
EW-12	GDSC1; GDSC2	0.4218	2.6316	-3.9973	0.2485
CHSA8926	GDSC2	0.5788	5.5887	-8.2718	0.9315
ES7	GDSC1; GDSC2	0.7487	3.7095	-4.255	0.4936
ES5	GDSC1; GDSC2	1.235	3.725	-4.0836	0.2075
EW-11	GDSC1; GDSC2	1.362	3.7008	-4.0322	0.1006
CAL-78	GDSC2; CTRP2; CCLE	4.924	27.153	-5.4576	28.4747
Hs 822.T	CTRP2	7.0682	8.2747	5.6228	0.5271
Hs 888.T	CTRP2	8.9662	38.1039	-7.6202	31.7156

Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MEC1	CTRP2	-12.6032	-2.1539	-12.7881	88.5147
JK1	CTRP2	-12.0701	-2.1284	-12.2324	88.2519
JM1	GDSC1; GDSC2; CTRP2	-4.978	-1.5001	-4.981	56.983
Kasumi-2	CTRP2; CCLE	-15.6443	-0.8334	-16.1637	87.5838
KMS-20	CTRP2	-15.2053	8.006	-17.71	77.813
KMS-28BM	CTRP2	-14.3304	4.3349	-15.7488	80.7878
HD-MY-Z	CTRP2; CCLE	-14.1029	42.9659	-31.0561	61.8561
SUP-T11	CTRP2	-13.9993	6.0571	-15.8333	78.748
MOTN-1	CTRP2	-13.8144	4.9476	-15.3387	79.7608
Hs 611.T	CTRP2	-13.7507	9.233	-16.5066	75.6104
Mino	CTRP2; CCLE	-13.6376	3.496	-14.7967	81.2607
M-07e	CTRP2	-13.4472	1.7327	-14.2243	83.3066
Ri-1	CTRP2	-13.4103	-0.4663	-13.8286	86.2906
OCI-Ly10	CTRP2; CCLE	-13.3239	23.6045	-21.5534	66.7032
Mono-Mac-1	CTRP2; CCLE	-13.3075	5.112	-14.8278	79.1921
NCO2	CTRP2; CCLE	-12.7024	0.5944	-13.2256	84.3902
KYO-1	CTRP2	-12.2658	3.7019	-13.3506	79.9446
KMS-18	CTRP2	-12.1063	-1.489	-12.3271	87.2204
MOLP-2	CTRP2	-11.9229	32.1191	-23.8831	62.6228
EB1	CTRP2; CCLE	-11.8909	2.8889	-12.7664	80.6418
MJ	CTRP2; CCLE	-11.8511	0.1489	-12.2487	84.4845
HuNS1	CTRP2	-11.7737	0.6692	-12.2409	83.6434
HPB-ALL	CTRP2	-11.7453	0.1792	-12.1399	84.3628
Ci-1	CTRP2; CCLE	-11.7412	-2.568	-11.8574	88.847
KE-97	CTRP2; CCLE	-11.6877	-4.9367	-11.7068	92.9965
RL	GDSC1; GDSC2; CTRP2	-10.7502	2.8737	-11.5259	72.6088
KMS-21-BM	CTRP2	-10.6256	-8.7905	-10.6256	99.2853
PL21	CTRP2	-10.5346	-8.5389	-10.5346	99.0099
U-937	CTRP2; CCLE	-10.4824	-8.4327	-10.4824	98.8837
OCI-Ly3	CTRP2	-10.4699	-7.8159	-10.4699	97.9642
SU-DHL-1	GDSC1; GDSC2; CTRP2	-10.448	11.0957	-13.5489	65.6225
Pfeiffer	CTRP2; CCLE	-10.3475	-6.2546	-10.3481	95.1679
SET-2	CTRP2	-10.203	7.5557	-12.1215	73.4099
KO52	CTRP2; CCLE	-10.1999	-1.6004	-10.3213	86.1226
BL-70	CTRP2; CCLE	-10.1598	-8.7503	-10.1598	99.3825
MOLT-3	CTRP2	-10.0831	-9.0464	-10.0831	99.7186
KMS-34	CTRP2; CCLE	-10.0736	-3.9381	-10.0909	90.4897
SEM	CTRP2	-10.0608	-4.7717	-10.0667	92.1402
F-36P	CTRP2; CCLE	-9.919	0.2132	-10.1997	82.6661
SU-DHL-5	GDSC2	-9.7471	-8.7251	-9.7482	31.1468
MOLM-6	CTRP2	-9.6591	5.9429	-11.0656	74.3799
KMS-11	GDSC2; CTRP2; CCLE	-9.0538	-7.4241	-9.0538	78.0896
Peer	CTRP2	-8.9581	-6.5166	-8.9581	94.8432
697	GDSC1; GDSC2; CTRP2; CCLE	-8.8551	-8.026	-8.8551	65.7719
KHM-1B	CTRP2; CCLE	-8.8517	-0.9851	-8.9617	83.4532
OCI-Ly19	GDSC1; GDSC2; CTRP2	-8.8051	-7.4697	-8.8051	76.8137
TF-1	CTRP2	-8.7438	44.8517	-26.734	57.3529
GA-10	GDSC1; GDSC2; CTRP2	-8.6681	-7.434	-8.6681	64.9466
JVM-3	GDSC1; GDSC2; CTRP2; CCLE	-8.6618	-7.3425	-8.6618	64.9188
OCI-Ly7	GDSC2	-8.651	-7.4878	-8.6511	53.4776
MM1.S	GDSC2; CTRP2	-8.5518	-6.0647	-8.5518	62.7862
SU-DHL-6	GDSC1; GDSC2; CTRP2; CCLE	-8.5211	-6.8551	-8.5211	64.2974
SU-DHL-10	GDSC2; CTRP2; CCLE	-8.4645	-7.4647	-8.4645	64.0479
KMS-26	CTRP2; CCLE	-8.4229	-6.5582	-8.4229	93.9884
SUP-M2	GDSC1; GDSC2; CTRP2; CCLE	-8.2785	-7.1148	-8.2785	63.2267
JURL-MK1	CTRP2	-8.2635	-5.9205	-8.2635	92.3581
HuT 78	CTRP2; CCLE	-8.2098	0.9092	-8.4692	79.0794
BV-173	GDSC1; GDSC2; CTRP2	-8.1944	-6.8753	-8.1944	62.8552
A4/Fukuda	GDSC1; GDSC2; CTRP2	-8.1054	-6.4517	-8.1054	62.4625
TALL-1 [Human adult T-ALL]	GDSC2; CTRP2	-8.0604	8.3848	-10.0459	62.8065
Namalwa	GDSC1; GDSC2; CTRP2	-8.0493	-6.5257	-8.0493	62.2149
RPMI-8226	GDSC1; GDSC2; CTRP2	-8.0272	-6.5818	-8.0272	62.1174
Jurkat	GDSC2; CTRP2; CCLE	-7.9864	-6.1289	-7.9864	61.9371
HT	GDSC1; GDSC2; CTRP2; CCLE	-7.9266	-4.1043	-7.9278	71.8705
KMS-12-BM	GDSC1; GDSC2; CTRP2; CCLE	-7.9266	-6.6107	-7.9266	61.6731
MV4-11	GDSC1; GDSC2; CTRP2	-7.918	-6.8695	-7.918	61.6352
RCH-ACV	GDSC2; CTRP2	-7.8561	-6.3836	-7.8561	71.9053
DoHH2	GDSC1; GDSC2; CTRP2; CCLE	-7.8462	-4.6518	-7.8465	71.6799
JeKo-1	GDSC2; CTRP2	-7.8084	-6.0918	-7.8084	71.6559
BDCM	CCLE	-7.7917	-3.8046	-7.8011	85.1534
SUP-B8	GDSC2	-7.7604	-6.4378	-7.7611	44.5436
MOLM-13	GDSC1; GDSC2; CTRP2	-7.7523	-6.3098	-7.7523	60.9036
ALL-SIL	GDSC1; GDSC2; CTRP2; CCLE	-7.6875	-3.3893	-7.691	60.5357
MOLT-16	GDSC1; GDSC2; CTRP2; CCLE	-7.6476	-6.583	-7.6476	60.4415
P12-Ichikawa	GDSC2; CTRP2; CCLE	-7.643	-6.871	-7.643	60.4212
CML-T1	GDSC2; CTRP2	-7.6367	-5.6373	-7.6367	60.3934
MHH-CALL-4	GDSC2; CTRP2	-7.608	-2.959	-7.6147	69.9175
JSC-1	GDSC1; GDSC2	-7.5505	-4.9631	-7.6119	32.2296
ATN-1	GDSC1; GDSC2	-7.5265	-6.2876	-7.5271	31.8222
AMO1	GDSC1; GDSC2; CTRP2; CCLE	-7.5087	-5.5845	-7.5087	59.8283
WSU-DLCL2	GDSC1; GDSC2; CTRP2	-7.5085	-7.0026	-7.5085	59.8274
NCI-H929	GDSC2; CTRP2	-7.4987	-2.9791	-7.5044	59.6892
SU-DHL-4	GDSC1; GDSC2; CTRP2; CCLE	-7.4834	-5.5658	-7.4834	69.9727
SIG-M5	GDSC1; GDSC2; CTRP2; CCLE	-7.4613	-6.7228	-7.4613	69.8642
BONNA-12	GDSC2	-7.4411	-4.4658	-7.5646	41.7905
KMS-27	CTRP2	-7.4254	-6.9866	-7.4254	89.7369
L-363	GDSC1; GDSC2; CTRP2; CCLE	-7.4042	-5.8863	-7.4042	59.367
OCI-AML-3	GDSC1; GDSC2; CTRP2	-7.3498	-6.6056	-7.3498	59.1268
MOLT-4	GDSC1; GDSC2	-7.3466	-5.8486	-7.3502	30.4829
SR	GDSC1; GDSC2; CTRP2	-7.3378	-6.4224	-7.3378	59.0739
Karpas-231	GDSC1; GDSC2	-7.3368	-6.1939	-7.3372	30.3975
WIL2 NS	GDSC1; GDSC2	-7.3329	-5.7603	-7.3379	30.3851
ALL-PO	GDSC1; GDSC2	-7.332	-5.4766	-7.3459	30.412
Reh	GDSC1; GDSC2; CTRP2; CCLE	-7.2547	-6.4096	-7.2547	58.7072
RS4;11	GDSC1; GDSC2; CTRP2	-7.2396	-5.7054	-7.2396	56.7304
RPMI-8402	GDSC1; GDSC2; CTRP2; CCLE	-7.202	-5.4608	-7.202	58.4744
HC-1	GDSC1; GDSC2	-7.1931	-5.7584	-7.1964	29.3294
OCI-AML-2	GDSC1; GDSC2; CTRP2; CCLE	-7.1651	-6.242	-7.1651	58.3116
MY-M12	GDSC1; GDSC2	-7.0902	-5.9173	-7.091	38.0318
NALM-6	GDSC1; GDSC2; CTRP2	-7.0779	-6.1404	-7.0779	57.9268
DEL	GDSC1; GDSC2; CTRP2; CCLE	-7.0729	-4.6627	-7.0729	57.9039
SKM-1	GDSC1; GDSC2; CTRP2	-7.0685	-6.3417	-7.0685	66.0774
DB	GDSC1; GDSC2; CTRP2	-7.0594	-4.4374	-7.0594	57.8433
BE-13	GDSC1; GDSC2	-7.059	-2.928	-7.507	30.0045
RPMI-6666	GDSC1; GDSC2; CTRP2	-7.0549	-6.1114	-7.0549	57.8251
HL-60	GDSC1; GDSC2; CTRP2	-7.0496	-6.4538	-7.0496	57.8016
EoL-1	GDSC1; GDSC2; CTRP2	-7.0278	-6.1395	-7.0278	57.7053
H9	GDSC1; GDSC2	-7.0122	-3.963	-7.1898	28.6368
PL-21	GDSC1; GDSC2	-6.9733	-4.4988	-7.0556	37.2362
NOMO-1	GDSC1; GDSC2; CTRP2	-6.9641	-5.8997	-6.9641	57.4244
ST486	GDSC1; GDSC2; CTRP2	-6.9611	-6.2715	-6.9611	57.4112
Loucy	GDSC1; GDSC2	-6.9495	-5.9332	-6.9499	27.49
NU-DUL-1	GDSC1; GDSC2; CTRP2	-6.938	-4.775	-6.938	63.449
KOPN-8	GDSC1; GDSC2	-6.9244	-5.8856	-6.9249	27.302
KE-37	GDSC1; GDSC2; CTRP2	-6.9239	-5.9474	-6.9239	57.2471
P31/FUJ	GDSC1; GDSC2; CTRP2; CCLE	-6.9041	-5.9643	-6.9041	57.1594
NU-DHL-1	CTRP2	-6.8495	4.7127	-7.6871	70.8474
JJN-3	GDSC1; GDSC2; CTRP2	-6.8414	-6.286	-6.8414	56.8827
MHH-PREB-1	GDSC1; GDSC2	-6.8131	-5.0667	-6.8317	26.5347
CRO-AP2	GDSC2	-6.8019	-2.9319	-7.233	36.7773
MOLM-16	GDSC2	-6.8002	-3.9264	-6.9716	35.7013
QIMR-WIL	GDSC1; GDSC2	-6.7885	-4.5935	-6.8469	35.2917
Farage	GDSC1; GDSC2	-6.7316	-5.0761	-6.7471	34.5182
ML-2	GDSC1; GDSC2	-6.7155	-5.2174	-6.7244	25.7652
SU-DHL-8	GDSC1; GDSC2; CTRP2; CCLE	-6.6647	-2.108	-6.6738	56.0474
KCL-22	GDSC1; GDSC2; CCLE	-6.6543	-4.1186	-6.6548	49.2347
OCI-AML-5	GDSC1; CTRP2; CCLE	-6.6155	-5.4649	-6.6155	73.0429
JM-1	CCLE	-6.5305	-3.2635	-6.5354	79.1098
SU-DHL-16	GDSC1; GDSC2	-6.5209	-4.3823	-6.5887	32.6697
MOLT-13	GDSC1; GDSC2	-6.5153	-5.0815	-6.5245	24.2635
Karpas-1106P	GDSC2	-6.5021	-4.4734	-7.6133	5.7383
CCRF-CEM	GDSC1; GDSC2	-6.4993	-4.9671	-6.5131	24.1611
MHH-CALL-2	GDSC2	-6.4801	-4.5494	-7.5579	5.3284
SUP-B15	GDSC1; GDSC2; CTRP2	-6.477	-4.1789	-6.4771	55.274
BC-3	GDSC1; GDSC2	-6.4421	-4.141	-6.5404	32.034
SCC-3	GDSC1; GDSC2	-6.3713	-4.4591	-6.4203	23.3344
Raji	GDSC1; GDSC2; CTRP2; CCLE	-6.3279	-2.6764	-6.3298	54.605
Daudi	GDSC1; GDSC2; CTRP2	-6.3136	-3.2888	-6.314	54.5503
PF-382	GDSC1; GDSC2; CTRP2	-6.2943	-3.2574	-6.2946	54.4647
Ramos.2G6.4C10	GDSC1; GDSC2	-6.2863	-5.3732	-6.2869	22.5121
K-562	GDSC1; GDSC2; CTRP2	-6.2754	-3.0806	-6.276	54.3802
Granta-519	GDSC1; GDSC2; CTRP2; CCLE	-6.2579	-3.2358	-6.2583	54.3044
Ku812	GDSC1; GDSC2; CTRP2; CCLE	-6.1664	-2.7516	-6.1676	53.8972
Karpas-45	GDSC1; GDSC2	-6.1563	-3.8135	-6.292	22.0592
BALL-1	GDSC1; GDSC2	-6.149	-4.4042	-6.1911	21.6391
Hs 445	GDSC1; GDSC2	-6.0822	-3.2121	-6.3584	22.0661
CTV-1	GDSC1; GDSC2	-6.0774	-3.2777	-6.335	21.9549
CMK-86	CCLE	-5.8512	-3.7425	-5.8514	75.58
SUP-T1	GDSC1; GDSC2; CTRP2; CCLE	-5.8479	-2.3565	-5.8497	52.493
HEL 92.1.7	CTRP2; CCLE	-5.8107	2.5747	-6.1379	70.8671
Ki-JK	CTRP2	-5.7869	25.226	-14.5835	57.4328
MOLP-8	GDSC1; GDSC2; CTRP2; CCLE	-5.6574	2.7578	-6.0022	51.4921
Jiyoye	GDSC1; GDSC2	-5.5548	-1.4254	-6.4365	20.6736
VL51	GDSC1; GDSC2	-5.5393	-1.3425	-6.4552	20.7045
EJM	GDSC1; GDSC2; CTRP2	-5.5147	-1.9065	-5.5176	51.024
MEC-1	CCLE	-5.2897	0.5378	-5.5129	66.5082
HDLM-2	GDSC1; GDSC2; CTRP2	-5.2703	1.5393	-5.4272	49.9499
KM-H2	GDSC1; GDSC2; CTRP2	-5.2212	-2.8337	-5.2212	49.7304
Kasumi-1	GDSC1; GDSC2; CTRP2	-5.2191	-2.3555	-5.2195	58.2527
ARH-77	GDSC1; GDSC2	-5.1826	-1.5072	-6.0145	17.7177
OPM-2	GDSC1; GDSC2; CTRP2; CCLE	-5.1403	-1.7779	-5.1423	49.374
KY821	GDSC1; GDSC2	-5.0911	-1.4692	-5.9362	17.1003
DG-75	GDSC1; GDSC2	-4.985	-2.2117	-5.5145	14.9345
LC4-1	GDSC1; GDSC2	-4.9359	0.2988	-6.5888	19.4992
RPMI-8866	GDSC1	-4.9022	-1.7796	-5.6071	24.9297
Karpas-299	GDSC1; GDSC2; CTRP2; CCLE	-4.8518	-1.0299	-4.8584	48.1057
P32/ISH	GDSC1; GDSC2	-4.8139	-4.2136	-4.816	11.4648
EM-2	GDSC1; GDSC2; CTRP2; CCLE	-4.7513	3.2379	-5.1068	47.8562
L-540	GDSC1; GDSC2; CTRP2	-4.7434	-1.7071	-4.7446	47.6229
CA46	GDSC1; GDSC2; CTRP2	-4.4845	0.3357	-4.5204	46.5196
HEL	GDSC1; GDSC2; CTRP2	-4.4487	-1.6075	-4.4495	54.2752
GR-ST	GDSC1; GDSC2	-4.4095	-0.3296	-5.781	14.4793
LP-1	GDSC1; GDSC2; CTRP2; CCLE	-4.3335	2.4275	-4.5377	53.3765
U266B1	GDSC1; GDSC2; CTRP2	-4.2673	-0.9722	-4.2704	45.5247
CTB-1	GDSC1; GDSC2	-3.9713	34.1292	-22.5689	43.8513
CESS	GDSC1; GDSC2	-3.9592	0.4645	-5.7491	13.1772
SUP-HD1	GDSC1; GDSC2; CTRP2	-3.9587	3.2509	-4.256	44.5251
NB4	GDSC1; GDSC2	-3.8785	-2.9219	-4.0593	6.9055
A3/Kawakami	GDSC1; GDSC2	-3.7573	-1.9951	-4.3575	6.19
Karpas-422	GDSC1; GDSC2; CTRP2; CCLE	-3.7237	1.1484	-3.7772	43.2097
NKM-1	GDSC1; GDSC2	-3.6053	1.093	-5.7481	12.326
HH [Human lymphoma]	GDSC1; GDSC2; CCLE	-3.5341	2.4955	-3.9997	34.4409
THP-1	GDSC1; GDSC2; CTRP2	-3.198	0.1647	-3.2053	47.8183
EHEB	GDSC1; CTRP2	-3.1604	3.0646	-3.3722	52.8279
MLMA	GDSC1; GDSC2	-3.1161	0.6881	-5.1345	8.3756
GDM-1	GDSC1; GDSC2	-3.1129	1.8409	-5.7078	11.045
LAMA-84	GDSC1; GDSC2	-3.0937	1.305	-5.4245	9.6886
L-428	GDSC1; GDSC2; CTRP2; CCLE	-2.9173	1.9563	-2.994	39.7108
OCI-M1	GDSC1; GDSC2; CTRP2	-2.9121	5.4941	-3.5855	40.6247
EB2	GDSC1; GDSC2; CCLE	-2.8795	1.5826	-3.0925	30.5294
DND-41	GDSC1; GDSC2	-2.8062	3.1475	-6.1134	12.2478
JVM-2	GDSC1; GDSC2; CTRP2	-2.7932	-0.2145	-2.7945	39.0153
NK-92MI	GDSC1; GDSC2	-2.6212	-0.0153	-4.4072	5.3494
MEG-01	GDSC1; GDSC2; CCLE	-2.4616	2.943	-2.9449	29.1056
KG-1	GDSC1; GDSC2; CCLE	-2.4429	-0.687	-2.4446	27.7617
SK-MM-2	GDSC1; GDSC2; CTRP2; CCLE	-1.7264	1.168	-1.7418	31.3046
KMOE-2	GDSC1; GDSC2	-1.6878	4.3071	-5.8485	8.9736
MHH-CALL-3	CTRP2	-1.3137	215.9301	-105.0915	49.9628
U-698-M	GDSC1; GDSC2	-0.6292	4.5261	-5.2643	4.8979
MN-60	GDSC1; GDSC2	-0.5267	3.8509	-4.9035	3.3342
TK [Human B-cell lymphoma]	GDSC2	-0.3374	2.0272	-7.3914	0.0307
BC-1	GDSC1; GDSC2	-0.3195	4.6132	-5.1247	3.9706
RC-K8	GDSC2	-0.3144	3.2349	-7.7795	0.3183
Mono-Mac-6	GDSC1; GDSC2; CTRP2	-0.3114	26.9308	-10.0749	40.7218
IM-9	GDSC1; GDSC2	-0.1257	1.3919	-3.77	0.053
VAL	GDSC2	-0.1224	2.4986	-7.4732	0.0504
ME1	GDSC1; GDSC2	0.0937	6.493	-5.7302	5.886
ROS-50	GDSC1; GDSC2	0.1226	8.6617	-6.7156	12.3001
AML-193	CTRP2	0.1337	34.8764	-13.5518	47.5274
P30/OHK	GDSC1; GDSC2	0.1959	8.204	-6.4548	8.6302
TUR	GDSC1; GDSC2	0.4517	2.1698	-3.833	0.049
YT	GDSC1; GDSC2	0.5407	2.165	-3.8022	0.0312
WSU-NHL	GDSC1; GDSC2	0.5872	2.4991	-3.8959	0.0756
HAL-01	GDSC1; GDSC2	0.733	2.9726	-4.004	0.1467
ME1	CTRP2	1.7558	30.2255	-9.783	43.9903
Toledo	CTRP2; CCLE	2.5211	13.3058	-0.8209	33.4582
P3HR-1	CTRP2; CCLE	4.2897	45.9332	-15.3805	42.5672
REC-1	CTRP2	6.0377	9.7603	4.1809	7.8443
MC116	GDSC1; GDSC2; CTRP2; CCLE	7.0445	7.8271	5.7869	0.1079
L-1236	GDSC1; GDSC2; CTRP2	7.1432	21.1433	-1.3298	15.2482
Karpas-620	GDSC1; GDSC2; CTRP2; CCLE	7.8848	9.3358	5.5666	0.1743
BL-41	GDSC1; GDSC2; CTRP2; CCLE	8.1935	29.4792	-3.9337	21.9775
KMM-1	CTRP2; CCLE	9.9828	40.8187	-8.1794	31.057

Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	-13.5015	3.9737	-14.7589	80.6101
TE8	CTRP2	-8.6038	5.4726	-9.9694	73.8447
TE-14	CTRP2	-10.8161	10.2727	-13.6626	71.7273
KYSE-510	GDSC2; CTRP2; CCLE	-9.8557	9.8995	-12.4951	65.3714
TE-11	GDSC1; GDSC2; CTRP2; CCLE	-9.5162	-7.9651	-9.5162	80.4765
TE-15	GDSC1; CCLE	-9.1142	-6.0179	-9.1147	82.8779
TE-8	GDSC1; GDSC2	-8.8787	-6.8753	-8.8826	41.9838
OE21	GDSC2; CTRP2; CCLE	-8.7094	3.6621	-9.4746	61.4111
TE-9	GDSC1; GDSC2; CCLE	-7.8696	-5.2901	-7.8699	55.4293
T.T	GDSC2	-7.738	-5.681	-8.1905	13.5215
TE-10	GDSC1; GDSC2; CTRP2	-7.5626	-3.4209	-7.5653	69.9382
KYSE-180	GDSC2; CTRP2; CCLE	-7.2774	-5.2392	-7.2774	58.8073
TE-4	GDSC2; CTRP2	-7.2182	-5.3169	-7.2182	56.6315
TE-6	GDSC1; GDSC2; CTRP2	-6.9499	-3.5159	-6.9513	55.3808
KYSE-70	GDSC2; CCLE	-5.9943	-2.5674	-6.004	45.8845
TE-5	GDSC1; GDSC2; CTRP2; CCLE	-5.8963	2.2377	-6.1793	52.4666
KYSE-270	GDSC2	-5.5841	1.7015	-9.9696	16.994
EC-GI-10	GDSC1; GDSC2; CTRP2	-3.3513	3.2995	-3.6114	41.8963
KYSE-410	GDSC2; CTRP2; CCLE	-3.0268	9.6397	-5.0263	42.533
KYSE-140	GDSC2; CTRP2; CCLE	-1.0389	66.8506	-30.4462	46.6097
OE33	GDSC2; CTRP2; CCLE	-0.6497	34.9175	-14.2906	43.165
KYSE-520	GDSC2; CTRP2; CCLE	0.7778	20.3631	-5.8683	35.3597
TE-1	GDSC1; GDSC2; CTRP2; CCLE	1.2216	17.0418	-3.8536	31.8611
KYSE-30	CTRP2; CCLE	1.4399	117.9572	-53.794	48.6352
KYSE-150	GDSC2; CTRP2; CCLE	1.5447	15.4371	-2.7796	29.4713
COLO 680N	GDSC2; CTRP2	3.785	17.0172	-1.4225	22.9942
OE19	GDSC2; CTRP2	5.956	35.8937	-8.954	31.3788
KYSE-450	GDSC2; CTRP2; CCLE	10.363	49.3463	-12.1212	29.8458

Cancer Drug Sensitivity Data Curated from 79 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	11.5583	37.8974	-5.5532	25.8318
CJM [Human melanoma]	CTRP2	-15.2805	1.3961	-16.1437	84.6886
MDA-MB-435S	CTRP2; CCLE	-14.0846	0.1547	-14.6405	85.7331
A2058	GDSC2; CTRP2; CCLE	-8.3838	-6.72	-8.3838	63.6913
Hs 944.T	CTRP2; CCLE	-8.2316	4.6819	-9.1856	73.6448
WM88	CTRP2; CCLE	-7.7217	40.1673	-23.5099	57.0644
A-431	GDSC2	-7.5454	-2.3206	-8.2388	44.0713
RPMI-7951	GDSC2; CTRP2; CCLE	-7.498	-3.9056	-7.4988	59.7556
DJM-1	GDSC1; GDSC2	-7.2153	-4.145	-7.3741	39.9155
WM983B	CTRP2; CCLE	-7.0367	14.7379	-11.2788	63.1303
Hs 852.T	CTRP2; CCLE	-7.0094	18.2804	-12.7271	61.4433
A-388	GDSC1; GDSC2	-6.9614	-3.0543	-7.363	38.361
HMCB	CCLE	-6.9549	-4.3481	-6.9555	83.2985
IGR-37	GDSC2; CTRP2; CCLE	-6.7452	-2.8458	-6.7478	56.4337
G-361	GDSC2; CTRP2; CCLE	-6.7253	4.5758	-7.5198	55.09
CP50-MEL-B	GDSC2	-6.7152	-1.7788	-7.537	37.3719
CHL-1	GDSC2; CCLE	-6.4261	-4.0999	-6.4264	48.0709
M14	GDSC2	-6.3457	-3.2745	-8.087	8.2974
G-mel	GDSC2	-6.1391	-2.9933	-6.492	30.053
IGR-39	CTRP2; CCLE	-6.11	8.5856	-7.9918	65.3019
HMV-II	GDSC2	-6.1069	7.2271	-13.1371	29.6429
COLO 783	GDSC2	-5.6187	-2.1134	-6.2377	26.3233
A-375	GDSC2; CTRP2; CCLE	-5.5878	-0.8369	-5.6077	51.3346
SH-4	GDSC1; GDSC2	-5.3045	0.2096	-6.9092	21.9024
IST-MEL1	GDSC1; GDSC2	-5.077	-2.0188	-5.6897	15.9802
MZ-MEL-2	GDSC1; GDSC2	-4.6304	0.9754	-6.6205	24.4293
MZ-MEL-7	GDSC1; GDSC2	-4.1953	1.5688	-6.5084	22.3064
MMAc-SF	GDSC1; GDSC2	-4.1257	-0.3785	-5.4885	16.4428
CP67-MEL	GDSC1	-3.991	-1.0836	-5.0195	16.3716
LB373-MEL-D	GDSC1; GDSC2	-3.9354	-0.5803	-5.213	14.1315
Hs 294T	CTRP2; CCLE	-3.5785	19.7674	-9.8742	54.7718
LOX-IMVI	GDSC1; GDSC2; CTRP2; CCLE	-3.5436	5.9572	-4.3956	43.3898
GAK	GDSC1; GDSC2	-3.3417	-0.8046	-4.5745	6.2129
LB2518-MEL	GDSC1; GDSC2	-3.3221	1.7978	-5.8592	16.004
COLO 679	GDSC2; CCLE	-3.1302	4.7272	-4.2303	33.8665
SF8657	CCLE	-2.7433	17.5175	-9.4647	49.7936
Mel JuSo	GDSC2; CTRP2	-2.4683	9.7012	-4.4495	40.5073
Hs 938.T	GDSC2; CCLE	-2.2018	11.1512	-5.9396	39.5685
WM115	GDSC2; CTRP2; CCLE	-1.7094	10.0386	-3.7659	37.7895
WT2-iPS	GDSC2; CTRP2; CCLE	-1.6757	9.2561	-3.4336	37.2347
Mel Ho	GDSC2; CTRP2; CCLE	-1.6718	12.3362	-4.6531	43.5763
WM793	GDSC2; CTRP2; CCLE	-1.4159	10.0715	-3.8116	34.7097
SK-MEL-5	GDSC2; CTRP2; CCLE	-1.3638	13.8268	-4.9709	42.9891
451Lu	GDSC2	-1.3482	4.414	-5.6944	9.8831
IGR-1	GDSC2; CTRP2	-1.0477	64.4181	-29.2447	46.4947
SK-MEL-2	GDSC1; GDSC2; CCLE	-0.9438	4.0252	-1.6219	21.9592
Hs 695T	CCLE	-0.9088	10.2018	-4.2159	41.5378
VMRC-MELG	GDSC2	-0.8784	6.8568	-6.547	13.2873
MeWo	GDSC2; CTRP2; CCLE	-0.8204	22.0146	-8.1949	40.3286
CP66-MEL	GDSC1; GDSC2	-0.7811	4.38	-5.2887	6.8311
WM35	GDSC2	-0.4166	5.1138	-8.4923	2.0023
WM1552C	GDSC2	-0.2681	2.1326	-7.4028	0.032
K029AX	CTRP2; CCLE	-0.2556	1913.5254	-952.9512	49.9654
IPC-298	GDSC2; CTRP2; CCLE	-0.239	18.8671	-6.1392	41.2492
HT-144	GDSC1; GDSC2; CTRP2; CCLE	0.0471	11.4289	-2.4786	31.8218
WM278	GDSC2	0.7044	3.1659	-7.4212	0.0159
COLO 741	CTRP2; CCLE	0.739	27.8217	-9.5298	45.6818
WM1799	CTRP2; CCLE	0.8967	23.2928	-7.7313	43.2943
Hs 936.T	CTRP2; CCLE	1.0511	35.5688	-13.0609	46.0851
SK-MEL-24	GDSC2; CTRP2; CCLE	1.1492	11.4421	-1.3459	27.3796
COLO 800	GDSC1; GDSC2; CTRP2	2.0604	17.9709	-3.4949	33.4202
COLO 829	GDSC1; GDSC2; CTRP2	5.4205	21.8042	-2.3612	22.5492
SK-MEL-1	GDSC1; GDSC2; CTRP2	6.0283	6.845	5.6306	1.1734
COLO 792	GDSC2; CTRP2	6.4984	28.1415	-4.6282	25.1728
SK-MEL-28	GDSC2; CTRP2	7.2454	8.332	5.6803	0.2162
SK-MEL-30	GDSC2; CTRP2; CCLE	7.6121	34.4895	-7.5968	28.5076
A101D	GDSC1; GDSC2; CTRP2	7.7418	8.8759	5.6771	0.0835
Hs 688(A).T	CTRP2	7.7897	17.3726	1.7608	14.2876
Hs 940.T	GDSC2; CTRP2	8.31	23.0559	-0.6549	17.3331
Malme-3M	CTRP2; CCLE	8.677	11.6463	5.0146	1.1997
SK-MEL-31	GDSC2; CTRP2; CCLE	9.0467	35.7539	-6.3885	27.0056
UACC-62	GDSC2; CTRP2; CCLE	9.3862	31.4323	-3.9835	20.7348
RVH-421	GDSC2; CTRP2; CCLE	9.3986	32.7973	-4.6498	24.0043
Hs 895.T	CTRP2; CCLE	10.1369	35.9018	-5.626	27.7109
UACC-257	GDSC1; GDSC2; CTRP2; CCLE	11.3037	29.1123	-1.4552	13.9176
SK-MEL-3	GDSC2; CTRP2	12.1801	38.1201	-5.212	21.8168
Hs 839.T	CTRP2	13.8207	29.517	-0.0187	11.8908
WM266-4	CTRP2; CCLE	14.7174	42.7419	-5.6762	22.4973
EquiPSC Line K2	GDSC2	-3.6261	1.4748	-5.9783	17.364

Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KYSE-220	GDSC2	-7.1789	-4.8897	-7.9988	10.271
OACP4 C	GDSC2	-7.1334	-3.9727	-8.4065	12.6498
HCE-4	GDSC1; GDSC2	-6.9089	-5.1727	-6.9249	36.2924
FLO-1	GDSC2	-6.8673	-4.9127	-7.7021	7.3791
OACM5.1 C	GDSC2	-6.5584	-2.061	-8.8645	13.6627
TE-12	GDSC1; GDSC2	-4.8833	1.29	-7.0122	27.195
ESO-51	GDSC2	-0.584	2.4767	-7.6184	0.1791
SK-GT-4	GDSC2	-0.0368	6.4447	-8.8415	2.8878
ESO-26	GDSC2	-0.0307	2.558	-7.4627	0.0431
KYAE-1	GDSC2	-0.024	2.7072	-7.5085	0.0605
KYSE-50	GDSC2	0.2455	3.6188	-7.7166	0.1721

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1; GDSC2; CTRP2	-2.2655	10.2263	-4.4314	39.9794

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NH-6	CTRP2	-14.0843	16.9342	-19.6247	70.577
IMR-32	CTRP2; CCLE	-10.261	-8.4208	-10.261	98.9227
KP-N-SI9s	CTRP2; CCLE	-9.254	1.3233	-9.6394	80.0252
IMR-5	GDSC1; GDSC2	-8.0848	-6.4878	-8.0868	36.0187
SK-N-MC-IXC	GDSC2	-7.9233	-6.1734	-7.9282	46.1906
CHP-134	GDSC2	-6.6601	-4.2177	-7.8705	7.8124
CHP-212	GDSC2; CTRP2; CCLE	-6.6431	-0.7619	-6.6895	55.8283
NB1	GDSC1; GDSC2; CTRP2	-6.3917	-4.6893	-6.3917	54.8975
SK-N-BE(2)	CTRP2; CCLE	-5.8127	45.2529	-24.1454	54.6279
MHH-NB-11	GDSC1; GDSC2; CTRP2	-5.7501	-2.8506	-5.7505	60.9909
SJNB-13	GDSC1; GDSC2	-5.1335	0.079	-6.6793	20.4465
SiMa	GDSC1; GDSC2; CTRP2; CCLE	-4.6269	0.9409	-4.7009	47.1732
CHP-126	GDSC1; GDSC2; CTRP2	-4.5378	5.1931	-5.2834	53.7755
SK-N-DZ	GDSC1; GDSC2; CTRP2; CCLE	-4.4739	-0.0669	-4.495	46.4574
Kelly	GDSC1; GDSC2; CTRP2; CCLE	-4.2611	-1.9066	-4.2612	45.4924
SK-N-SH	GDSC2; CTRP2; CCLE	-4.032	3.8636	-4.4429	44.9419
SK-N-AS	GDSC2; CTRP2; CCLE	-3.9447	8.3225	-5.5545	45.4769
KP-N-YS	GDSC1; GDSC2	-3.7677	3.2349	-6.9572	23.0145
TGW	GDSC1; GDSC2	-3.4989	-1.2411	-4.4919	6.1799
NB69	GDSC1; GDSC2	-3.275	1.4311	-5.6366	11.0655
SK-N-BE(2)-M17	GDSC1; GDSC2	-3.2736	-0.6181	-4.6108	6.2359
GI-ME-N	GDSC1; GDSC2	-3.2729	5.9974	-7.9179	20.5828
GOTO	GDSC1; GDSC2	-3.2353	1.7603	-5.7682	11.5873
SJNB-6	GDSC1; GDSC2	-3.0044	0.1643	-4.7837	8.6381
KP-N-RT-BM-1	GDSC1; GDSC2	-2.8684	3.8852	-6.531	18.262
LA-N-6	GDSC1; GDSC2	-1.0999	3.9512	-5.2869	7.3915
SJNB-17	GDSC1; GDSC2	-0.6538	8.4687	-7.142	15.73
SK-N-FI	GDSC1; GDSC2; CCLE	-0.5671	3.4975	-1.0393	19.4703
SJNB-5	GDSC1; GDSC2	-0.4527	4.1691	-5.0026	4.8115
NB(TU)1	GDSC1; GDSC2	-0.206	2.9894	-4.3806	1.2385
SJNB-7	GDSC1; GDSC2	0.24	3.1351	-4.2455	0.6576
SJNB-14	GDSC1; GDSC2	0.2998	3.1295	-4.2195	0.5787
SJNB-12	GDSC2	0.4061	3.3314	-7.57	0.0668
NH-12	GDSC1; GDSC2	0.4444	2.7924	-4.0445	0.2404
SJNB-10	GDSC1; GDSC2	0.6473	2.4899	-3.8728	0.0575
KP-N-YN	GDSC1; GDSC2; CTRP2	8.0316	10.9061	5.0017	1.1433

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-478	CTRP2	-9.3016	-0.8656	-9.4402	83.8301
HuCC-T1	GDSC2; CTRP2; CCLE	-0.4444	21.7231	-7.6927	39.2825
SNU-308	CTRP2	0.2656	31.7334	-11.8852	47.057
SNU-869	CTRP2	0.3903	105.721	-48.5807	49.0368
SNU-1079	CTRP2	1.7171	23.901	-6.7047	42.5285
SNU-1196	CTRP2	3.6558	18.6529	-2.9491	31.8562
SNU-245	CTRP2	5.0104	27.4561	-5.5348	35.2694
HuH-28	CTRP2	9.4384	22.9624	0.22	16.6447

Cancer Drug Sensitivity Data Curated from 92 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
BT-20	GDSC2; CTRP2; CCLE	-9.3413	27.5512	-19.2102	55.7992
HMC-1-8	CTRP2; CCLE	-7.7677	1.7956	-8.1176	76.8254
Hs 578T	GDSC2; CTRP2; CCLE	-7.6745	-0.7103	-7.757	59.9325
OCUB-M	GDSC1; GDSC2	-7.6724	-5.6691	-7.6872	32.9706
HCC1806	GDSC2; CTRP2; CCLE	-7.5201	-3.6323	-7.5218	59.8367
MDA-MB-468	GDSC2; CTRP2; CCLE	-7.0473	8.668	-9.0367	55.1233
MRK-nu-1	GDSC1; GDSC2	-6.7807	-3.5361	-7.0348	27.2019
BT-549	GDSC2; CTRP2; CCLE	-6.4457	0.9431	-6.6057	54.7876
HCC1187	GDSC1; GDSC2; CCLE	-6.3773	-3.914	-6.3778	47.8222
AU565	GDSC2; CTRP2; CCLE	-6.3456	-1.3186	-6.3659	54.6259
EFM-19	GDSC2; CCLE	-6.1521	-3.1227	-6.1557	46.6789
CAL-148	GDSC1; GDSC2; CTRP2	-5.5062	-2.721	-5.5065	50.9885
CAL-85-1	GDSC2; CTRP2; CCLE	-5.3504	2.0356	-5.5697	50.2807
SK-BR-3	CCLE	-5.2856	-0.0612	-5.4271	67.3241
HCC1599	GDSC1; GDSC2	-5.279	-2.5936	-5.6834	22.0091
HCC1954	GDSC2; CCLE	-5.247	-2.0871	-5.2563	42.0787
HCC1395	GDSC2; CTRP2; CCLE	-4.9563	0.6894	-5.0264	48.5959
HCC70	GDSC2; CCLE	-4.8832	-0.032	-5.0041	40.4594
JIMT-1	GDSC2; CTRP2	-4.6323	3.9244	-5.1045	47.4288
Evsa-T	GDSC1; GDSC2	-4.4681	1.0526	-6.5059	17.8701
HCC38	GDSC2	-4.3991	-0.2948	-5.8058	14.3538
DU4475	GDSC1; GDSC2; CTRP2	-4.2353	-0.1677	-4.2496	45.3998
Hs 739.T	CCLE	-3.7951	24.1615	-13.6667	51.8786
COLO 824	GDSC1; GDSC2	-3.1333	2.9087	-6.2582	13.5839
UACC-812	GDSC2; CCLE	-2.9406	6.9074	-4.8507	34.6228
MDA-MB-436	GDSC2; CCLE	-2.8499	3.2381	-3.4508	31.3499
HCC1143	GDSC2; CTRP2	-2.6927	7.037	-4.0168	38.1527
MDA-MB-157	GDSC2; CTRP2; CCLE	-2.3371	7.0936	-3.4092	38.8432
CAL-51	GDSC2; CTRP2	-2.1734	2.8193	-2.2924	36.5251
HCC2157	GDSC1; GDSC2	-2.1352	5.7214	-6.8715	14.162
UACC-893	GDSC2	-1.9641	6.838	-7.3194	19.2655
BT-474	GDSC1; GDSC2; CTRP2; CCLE	-1.9172	4.9562	-2.3732	36.0629
CAMA-1	GDSC2; CTRP2; CCLE	-1.7755	10.7568	-4.1173	38.4128
HCC2218	GDSC1; GDSC2	-1.7598	7.5883	-7.5108	19.7448
MCF-7	GDSC2; CTRP2; CCLE	-1.6456	11.1212	-4.1258	38.1185
MDA-MB-330	GDSC2	-1.6143	7.5051	-7.3866	18.7014
MDA-MB-415	GDSC2; CCLE	-1.6135	9.9423	-4.7971	31.3492
EFM-192A	GDSC2; CTRP2	-1.2763	10.3391	-3.4223	36.281
HDQ-P1	GDSC2; CTRP2; CCLE	-0.8812	9.4111	-2.6409	34.111
MDA-MB-453	GDSC2; CTRP2; CCLE	-0.5415	22.4025	-8.1106	39.7784
MFM-223	GDSC1; GDSC2	-0.0279	4.3423	-4.8507	2.6462
BT-483	GDSC2	0.1619	6.2064	-5.5914	5.0942
MDA-MB-231	GDSC2; CTRP2	0.6206	15.9756	-3.9394	33.1052
YMB-1-E	GDSC2	0.6663	9.3147	-6.7067	11.109
HCC1569	GDSC2; CCLE	0.7513	16.2015	-5.5572	31.8377
MDA-MB-175-VII	GDSC2; CCLE	2.8435	14.3776	-2.8197	18.3077
HCC1500	GDSC2; CTRP2	4.7422	17.8273	-0.9646	20.5341
ZR-75-30	GDSC2; CTRP2; CCLE	5.3009	19.1906	-1.1581	20.1731
CAL-120	GDSC2; CTRP2	5.3026	21.6869	-2.4033	22.7961
HCC1419	GDSC2; CTRP2	5.5015	18.2831	-0.5331	18.4581
HCC1428	GDSC2; CTRP2	5.7377	20.6151	-1.4981	20.3204
HCC202	CTRP2	6.7495	54.3439	-17.5203	40.7256
T-47D	GDSC2; CTRP2; CCLE	8.25	29.5541	-3.9267	21.9004
ZR-75-1	CTRP2; CCLE	8.5638	44.9951	-11.3733	35.5543
HCC1937	GDSC2; CTRP2	8.7868	21.5454	0.4436	12.1014
MDA-MB-361	GDSC2; CTRP2	9.273	29.4199	-3.0738	19.2167
KPL-1	CTRP2	10.5544	24.2256	0.3822	15.3616
Hs 578Bst	CTRP2	11.432	26.9964	-0.3533	15.5194
BT 145	CTRP2	-15.9057	1.1562	-16.7747	85.2327
BT164	CTRP2	-14.8407	16.6695	-20.3284	71.3734
BT 112	CTRP2	-14.6597	17.5258	-20.4678	70.7444
BT 179	CTRP2	-14.4731	18.1387	-20.5105	70.2563
BT 231	CTRP2	-13.536	9.8879	-16.4851	74.8761
BT 504	CTRP2	-13.4028	16.2336	-18.6268	70.3599
BT 416	CTRP2	-11.3613	4.364	-12.5198	78.2808
BT 224	CTRP2	-6.9711	113.9837	-59.1219	52.4966
BT 428	CTRP2	-4.5788	50.7377	-25.6736	53.0698
BT 286	CTRP2	-3.6045	37.539	-18.323	52.8216
BT 131	CTRP2	-3.3191	50.4686	-24.3836	51.8823
BT 245	CTRP2	-2.6758	21.5391	-9.7874	52.6521
BT 159	CTRP2	-2.3697	91.2565	-43.7618	50.5319
BT 359	CTRP2	-0.5598	560.1455	-276.5287	49.9117
BT 271	CTRP2	0.1039	259.0227	-125.4286	49.6682
BT 172	CTRP2	0.7779	83.1575	-36.9843	48.5127
BT147	CTRP2	4.0478	47.9628	-16.6011	43.231
BT 422	CTRP2	4.0558	27.918	-6.5908	38.0121
BT 440	CTRP2	4.4033	33.8628	-9.2551	39.4974
BT 330	CTRP2	5.9342	64.4318	-23.2412	43.1448
BT 216	CTRP2	6.3252	35.5258	-8.463	36.0969
BT 444	CTRP2	6.5175	31.8874	-6.485	33.8845
BT 248	CTRP2	7.0496	34.4197	-7.3145	33.9855
BT 320	CTRP2	7.4249	8.5058	5.6887	0.1924
BT 187	CTRP2	8.1127	32.9539	-5.728	30.6077
BT 333	CTRP2	9.0033	44.4798	-10.7665	34.5918
BT 139	CTRP2	9.298	37.3234	-6.9732	30.551
BT 498	CTRP2	9.4593	22.2685	0.572	15.575
BT 228	CTRP2	9.6825	49.6385	-12.7999	35.332
BT 232	CTRP2	9.884	40.189	-7.9431	30.9211
BT 239	CTRP2	10.5406	52.7589	-13.6797	35.046
BT 482	CTRP2	11.0639	41.5665	-7.7266	29.2738
BT 340	CTRP2	14.3131	48.5085	-8.7532	26.9772
BT 328	CTRP2	15.0342	44.1085	-6.1168	22.8352

Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
1321N1	CCLE	-8.3957	2.8379	-9.3926	72.9755
D-566MG	GDSC2	-7.8749	-3.4163	-8.2653	46.3749
KNS-60	CCLE	-7.8112	-5.4463	-7.8113	89.3428
8-MG-BA	GDSC1; GDSC2; CTRP2; CCLE	-7.6403	-4.3383	-7.6406	60.3931
MOG-G-UVW	GDSC2	-7.5621	-4.5112	-8.5469	14.9936
Hs 683	GDSC2; CTRP2; CCLE	-7.5291	-2.3807	-7.5434	69.2557
Onda 10	GDSC1; GDSC2	-7.3924	-3.2459	-7.7788	42.2679
Becker	GDSC1; GDSC2; CTRP2	-6.9338	-5.4579	-6.9338	57.2905
YH-13	GDSC2; CTRP2	-6.6765	-3.8087	-6.6767	56.1524
M059J	GDSC2; CCLE	-6.5598	-3.5154	-6.5626	48.7546
Daoy	GDSC2; CTRP2; CCLE	-6.4837	0.2838	-6.5874	55.036
D-423MG	GDSC2	-6.4837	0.9087	-8.4264	38.6668
GI-1	GDSC1; GDSC2; CCLE	-6.4483	-3.3754	-6.4515	48.187
KS-1 [Human Krukenberg tumour]	GDSC1; GDSC2	-6.3724	-2.4225	-6.9247	25.3426
DK-MG	GDSC2; CTRP2; CCLE	-6.0269	0.7215	-6.1452	53.1251
PFSK-1	GDSC2	-6.0086	-0.6292	-9.1395	13.7267
SF539	GDSC1; GDSC2; CTRP2	-5.6299	-2.7069	-5.6303	51.5339
KNS-42	GDSC1; GDSC2; CTRP2; CCLE	-5.5685	22.9908	-13.3413	53.5758
MOG-G-CCM	GDSC2; CCLE	-5.5644	-1.889	-5.5842	43.7153
GaMG	GDSC2; CTRP2; CCLE	-5.5167	-0.9385	-5.5328	51.0258
KINGS-1	GDSC1; GDSC2	-5.3167	-1.1327	-6.3149	19.4253
42-MG-BA	GDSC2; CTRP2; CCLE	-5.0127	10.2228	-7.3753	49.1989
D-542MG	GDSC2	-4.8489	0.8469	-6.7841	25.8203
H4	GDSC2; CCLE	-4.8318	-1.7988	-4.8412	39.9626
D-247MG	GDSC1; GDSC2	-4.7563	9.0091	-10.6991	36.9088
LN-229	GDSC2; CTRP2; CCLE	-4.7132	0.5009	-4.7637	47.5307
Onda 11	GDSC1; GDSC2	-4.3047	0.9528	-6.3055	21.6545
SNU-738	CTRP2	-4.1976	15.756	-8.7314	57.0876
M059K	CTRP2	-4.0329	179.0013	-88.969	50.7714
KALS-1	GDSC1; GDSC2; CTRP2; CCLE	-3.9985	9.037	-5.8575	45.8033
SF126	GDSC1; GDSC2; CTRP2; CCLE	-3.9402	0.5579	-3.9712	51.6206
A-172	GDSC2; CTRP2; CCLE	-3.896	7.5766	-5.2579	45.146
D-245MG	GDSC2	-3.866	6.4511	-8.6689	29.5249
D-336MG	GDSC1; GDSC2	-3.8126	1.3911	-6.0778	18.7571
D-263MG	GDSC1; GDSC2	-3.638	1.2278	-5.8436	12.8421
SF268	GDSC1; GDSC2; CTRP2	-3.4964	7.9914	-4.9578	43.76
D283 Med	GDSC1; GDSC2; CTRP2	-3.2368	2.5632	-3.3892	41.2386
LN-18	GDSC2; CTRP2; CCLE	-3.1585	-0.9715	-3.1587	40.6254
SW1088	GDSC2; CTRP2; CCLE	-2.8199	25.3331	-11.7097	45.4972
U-118MG	GDSC2; CTRP2; CCLE	-2.3841	15.6672	-6.8248	42.4057
KNS-81-FD	GDSC1; GDSC2	-2.034	2.9071	-5.4127	10.032
DBTRG-05MG	GDSC2; CTRP2; CCLE	-0.9419	9.5401	-3.0945	32.3621
SNB-75	GDSC1; GDSC2; CTRP2	-0.8816	15.4897	-5.2174	41.9724
SF295	GDSC2; CTRP2; CCLE	-0.8665	8.5484	-2.304	38.5894
CCF-STTG1	CTRP2	-0.7714	3018.5411	-1505.8876	49.9875
AM-38	GDSC1; GDSC2; CTRP2	-0.6998	2.7814	-0.7441	29.8695
D-502MG	GDSC1; GDSC2	-0.6209	5.8715	-5.8814	9.6562
CAS-1	GDSC1; GDSC2; CTRP2; CCLE	-0.2262	13.1644	-3.5128	34.1312
LN-405	GDSC2	-0.1336	2.2169	-7.3866	0.0244
SK-MG-1	GDSC2	-0.1143	3.0107	-7.6369	0.1439
YKG-1	GDSC2; CTRP2; CCLE	-0.101	50.5528	-21.518	46.2444
ONS-76	GDSC1; GDSC2; CTRP2	-0.0548	18.4145	-5.746	36.7253
SNU-1105	CTRP2	0.0623	31.9467	-12.1769	47.4354
TM-31	CTRP2	0.2516	15.4295	-4.0524	44.3701
D-392MG	GDSC2	0.3661	3.3045	-7.5744	0.0708
SNU-489	CTRP2	0.4992	17.9716	-4.9961	44.2818
KNS-81	CTRP2; CCLE	1.0394	20.9421	-6.4472	42.5697
SNU-626	CTRP2	1.5927	15.9351	-2.9683	39.5826
SW1783	GDSC2; CTRP2	3.173	14.1819	-0.6098	22.1419
U-87MG ATCC	GDSC1; GDSC2; CTRP2; CCLE	4.0206	14.1222	0.2158	18.7947
GB-1	GDSC1; GDSC2; CTRP2; CCLE	4.8252	16.6254	-0.2936	18.842
GOS-3	CTRP2	6.1348	87.4535	-34.5849	44.9045
SNU-201	CTRP2	6.6436	27.8072	-4.3418	30.9331
U-251MG	GDSC2; CTRP2	7.0734	20.4801	-0.3349	15.9445
SNU-466	CTRP2	7.8389	28.0446	-3.4983	27.6422
T98G	GDSC2; CTRP2; CCLE	8.2036	32.7331	-5.546	24.5548
NMC-G1	GDSC1; GDSC2; CTRP2	8.4786	28.3918	-3.1711	22.5566
GMS-10	CTRP2; CCLE	9.9612	58.7832	-17.1361	37.5355
KG-1-C	CTRP2	13.9334	35.5956	-2.787	18.2293

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ETK-1	GDSC1; GDSC2	-8.1774	-5.7647	-8.2027	36.7976
TGBC24TKB	GDSC1; GDSC2	-6.3914	-3.9663	-6.5167	23.7817
TGBC1TKB	GDSC1; GDSC2	-5.2079	-1.1593	-6.1915	18.5652

Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHUEM-7	CTRP2	-14.006	5.6191	-15.7225	79.1981
JHUEM-1	CTRP2	-13.7959	11.0216	-17.1459	74.2077
HEC-151	CTRP2; CCLE	-10.6509	3.9322	-11.6455	78.0457
HEC-265	CTRP2; CCLE	-10.3917	3.0214	-11.1671	78.9479
JHUEM-3	CTRP2	-10.1689	19.5916	-16.5702	65.1914
HEC-108	CTRP2	-9.5092	14.3839	-13.7611	67.1111
MFE-319	GDSC2; CTRP2; CCLE	-8.2215	3.1652	-8.8433	60.252
HEC-251	CTRP2; CCLE	-8.1885	11.8918	-11.402	66.794
MFE-296	GDSC2; CTRP2; CCLE	-7.6102	3.9032	-8.3319	58.1046
RL95-2	GDSC1; GDSC2; CTRP2; CCLE	-7.3573	-4.2289	-7.3576	59.1513
ESS-1	GDSC2; CTRP2; CCLE	-7.2565	-2.7834	-7.2624	58.6378
JHUEM-2	CCLE	-7.1213	-4.6039	-7.1216	84.6141
AN3-CA	GDSC2; CTRP2; CCLE	-6.1013	4.7354	-6.8775	52.9525
HEC-1-A	CTRP2; CCLE	-1.7245	35.0518	-15.352	50.3876
TEN	CCLE	-0.5342	25.7667	-11.4479	45.3274
HEC-6	CTRP2; CCLE	0.1232	145.4921	-68.6732	49.4022
MFE-280	GDSC2; CCLE	0.2175	8.3477	-2.24	21.2795
HEC-1-B	CTRP2; CCLE	1.246	23.3707	-6.8831	43.6081
KLE	GDSC1; GDSC2; CTRP2; CCLE	1.9648	15.5392	-2.4196	28.0514
HEC-50B	CTRP2	3.3253	35.6575	-11.085	42.1059
EN	GDSC2; CTRP2; CCLE	4.8305	40.0233	-11.9669	35.2733
EFE-184	CTRP2; CCLE	6.2155	15.7354	1.3407	18.5879
HEC-59	CTRP2; CCLE	6.9901	45.3626	-12.8323	38.3028
Ishikawa (Heraklio) 02 ER-	CTRP2; CCLE	-8.2042	-4.6503	-8.2047	89.6996

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW13	GDSC2	-7.1314	-5.6021	-7.6112	7.7071
KTCTL-140	GDSC2	-6.3379	-1.2293	-7.3518	34.7569
RXF 393L	GDSC1; GDSC2	-5.9736	-1.2983	-6.9281	31.4909
BB65-RCC	GDSC1; GDSC2	-5.3264	-1.2114	-6.2906	25.5587
HA7-RCC	GDSC1; GDSC2	-5.2	-0.1281	-6.6491	26.8052
TK-10	GDSC1; GDSC2	-4.9451	-2.0248	-5.5487	14.9608
KTCTL-21	GDSC2	-4.8186	1.04	-6.8483	26.0021
LB1047-RCC	GDSC1; GDSC2	-4.5556	-0.0309	-6.0643	21.2814
NCC010	GDSC2	-4.1847	-0.3555	-5.5738	16.8877
KTCTL-13	GDSC2	-4.1576	-1.2536	-5.1145	14.0247
LB996-RCC	GDSC1; GDSC2	-3.8381	0.9415	-5.8768	13.4689
KTCTL-26A	GDSC2	-3.4314	0.9277	-5.5387	14.2186
KTCTL-1M	GDSC2	-1.749	2.7615	-5.1737	7.7882
NCC021	GDSC2	-1.4588	4.8588	-5.9829	11.6721
769-P	GDSC2; CTRP2; CCLE	-1.3501	3.6701	-1.523	33.0182
TUHR4TKB	CTRP2	-0.7919	10.7703	-3.0829	47.2727
BFTC-909	GDSC2; CTRP2; CCLE	-0.7469	17.8995	-6.1869	38.5043
786-O	GDSC2; CTRP2; CCLE	-0.6802	6.5239	-1.4307	31.3241
KTCTL-195	GDSC2	-0.2269	4.0926	-8.0437	0.7353
SW156	GDSC2	-0.1267	10.9862	-8.0199	18.0102
LB2241-RCC	GDSC1; GDSC2	-0.0002	2.2714	-4.0256	0.4213
A-704	GDSC1; GDSC2	0.1324	7.7244	-6.2717	7.9936
SN12C	GDSC2	0.6079	3.1979	-7.4621	0.0251
CAL-54	GDSC2; CTRP2	0.7825	16.0858	-3.8314	32.6358
Caki-2	CTRP2; CCLE	1.2441	25.1783	-7.7679	44.054
UO-31	GDSC2; CTRP2	1.9288	9.2274	0.4107	25.4857
KMRC-20	GDSC2; CTRP2	2.1548	12.3995	-0.7598	24.2278
OS-RC-2	GDSC1; GDSC2; CTRP2	2.5352	12.9468	-0.6382	23.2818
TUHR10TKB	CTRP2	3.3599	40.2276	-13.3329	42.981
SNU-1272	CTRP2	3.9577	21.0381	-3.2554	34.3191
KMRC-1	GDSC2; CTRP2; CCLE	4.402	24.7236	-4.6969	28.0779
A-498	GDSC1; GDSC2; CTRP2	5.6971	6.3369	5.559	1.8738
VMRC-RCZ	GDSC2; CTRP2; CCLE	7.9904	24.6929	-1.7119	17.9443
TUHR14TKB	CTRP2	8.5855	10.8713	5.279	0.5778
RCC10RGB	GDSC1; GDSC2; CTRP2	9.2415	17.6232	2.6534	6.0336
ACHN	GDSC2; CTRP2; CCLE	10.1955	25.0197	-0.2461	12.3141
VMRC-RCW	GDSC2; CTRP2; CCLE	10.4591	28.0667	-1.5397	16.7805
KMRC-2	CTRP2; CCLE	11.3752	38.7231	-6.0931	26.8274
Caki-1	GDSC2; CTRP2	15.7107	35.3983	-1.5731	11.7783

Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
GP2d	CTRP2	-13.8756	9.6804	-16.7865	75.3439
SW403	CCLE	-8.2093	3.8303	-9.4695	71.2003
SW48	GDSC2; CTRP2; CCLE	-8.0071	-6.229	-8.0071	62.0284
SNU-175	GDSC2; CTRP2	-7.4505	-5.5603	-7.4505	59.5716
RKO	GDSC1; GDSC2; CTRP2; CCLE	-7.2659	-5.1378	-7.2659	58.7563
HCC2998	GDSC2	-7.2125	-5.124	-7.9175	9.885
COLO205	GDSC2; CTRP2; CCLE	-7.2001	-6.5893	-7.2001	58.466
GP5d	GDSC2	-7.1623	-6.1997	-7.3716	6.3773
KM12	GDSC1; GDSC2; CTRP2	-7.1367	-5.1299	-7.1367	58.1861
DiFi	GDSC2	-6.6948	-4.2974	-7.8598	7.8466
SNU-283	GDSC2	-6.6685	-4.132	-6.7891	34.1664
SW620	GDSC2; CCLE	-6.5995	-2.8488	-6.6117	48.9613
CaR-1	GDSC2	-6.588	-4.6152	-7.612	5.9691
SW948	GDSC2	-6.4787	5.8593	-12.7583	29.6481
SNU-C2B	GDSC1; GDSC2; CCLE	-6.0466	-3.2778	-6.0485	46.1384
SNU-81	GDSC2; CTRP2	-5.4359	0.9847	-5.5487	58.6855
LS180	GDSC2; CTRP2	-5.1632	1.0238	-5.2665	49.493
NCI-H508	GDSC2; CTRP2	-5.1565	6.8794	-6.4173	55.6008
SNU-407	GDSC2; CTRP2	-5.0668	3.6935	-5.5301	49.1539
SNU-61	GDSC2; CTRP2	-5.0636	6.042	-6.0775	49.2206
HCT 116	GDSC2; CTRP2; CCLE	-4.6646	0.6935	-4.7243	47.326
LoVo	GDSC2; CTRP2	-4.6149	2.4557	-4.9199	44.9766
HT115	GDSC2; CTRP2	-4.5267	-0.9859	-4.5312	54.659
SNU-C2A	CTRP2; CCLE	-4.4824	8.4623	-6.1845	61.1628
SW480	CCLE	-4.418	10.0712	-7.7177	55.6633
MDST8	GDSC1; GDSC2; CTRP2	-3.5829	2.9364	-3.8904	40.4027
T84	GDSC2; CTRP2; CCLE	-3.3677	3.5529	-3.67	42.0256
COLO201	CTRP2; CCLE	-3.2465	9.9831	-5.3893	56.5505
HT-29	GDSC2; CTRP2; CCLE	-3.2095	3.0709	-3.4256	41.2204
SW626	GDSC2	-3.1564	1.0539	-5.3734	9.3738
LS513	GDSC1; CTRP2; CCLE	-3.136	-0.4172	-3.1375	52.9619
SK-CO-1	GDSC2; CTRP2; CCLE	-3.0806	9.98	-5.2103	42.8352
COLO 320HSR	GDSC1; GDSC2	-2.8263	-0.2303	-4.451	4.5838
SNU-C5	GDSC2; CTRP2	-2.8258	18.9419	-8.7417	44.4195
SW1417	GDSC2; CTRP2; CCLE	-2.5611	14.1747	-6.3579	42.4655
CCK-81	GDSC2; CCLE	-1.7549	0.7185	-1.7874	24.3321
NCI-H747	GDSC1; GDSC2; CTRP2; CCLE	-1.6685	9.5997	-3.5545	37.3938
HCT 15	GDSC2; CTRP2; CCLE	-1.189	2.6661	-1.2449	32.0542
DLD-1	CTRP2	-0.4565	8.7983	-1.9551	45.2488
HCT 8	CTRP2	-0.3025	3.7398	-0.4158	42.5571
SW837	GDSC2	-0.2148	2.0929	-7.373	0.0231
SW1116	GDSC2	-0.0427	2.7803	-7.5382	0.0754
CL-11	GDSC1; GDSC2; CTRP2	0.1601	6.1121	-0.396	27.2413
LS123	GDSC1; GDSC2; CTRP2; CCLE	0.2109	16.3304	-4.5096	34.7022
SNU-C1	GDSC1; GDSC2; CTRP2	0.2725	11.9968	-2.4895	31.3806
HT-55	GDSC2; CTRP2	0.7218	9.8391	-1.4939	25.4624
NCI-H716	GDSC1; GDSC2; CTRP2	1.9904	11.0104	-0.2952	23.4397
COLO 320	CTRP2; CCLE	2.5681	14.4348	-1.3107	34.333
LS1034	GDSC1; GDSC2; CTRP2	2.5971	12.9298	-0.5696	23.0155
C2BBe1	GDSC1; GDSC2; CTRP2; CCLE	3.8158	18.4607	-2.1065	24.38
SW1463	GDSC2; CTRP2	4.1302	15.6711	-0.4445	20.2366
COLO 678	GDSC2; CTRP2; CCLE	4.4472	25.404	-4.9966	28.4642
HCC-56	CTRP2; CCLE	4.9251	45.2113	-14.4794	41.4947
LS411N	GDSC1; GDSC2; CTRP2; CCLE	5.8453	6.7067	5.5355	1.6943
CW-2	GDSC1; GDSC2; CTRP2	7.6257	10.731	4.851	1.7633
SNU-503	CTRP2	7.8326	77.0243	-27.9666	42.709
RCM-1 [Human ESC]	GDSC2; CTRP2	9.798	23.3943	0.2635	11.5065

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1; GDSC2	0.7668	2.9814	-3.9953	0.1343

Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-398	GDSC2; CCLE	-8.11	-6.1452	-8.11	56.6579
PLC/PRF/5	CTRP2; CCLE	-6.239	15.9957	-10.9578	61.1116
JHH-7	GDSC2; CCLE	-5.9276	-2.6911	-5.9345	45.5406
SNU-423	GDSC2; CTRP2; CCLE	-5.5873	4.6648	-6.3013	51.1281
JHH-5	CTRP2; CCLE	-5.1378	160.5551	-80.7166	51.2178
HLF	CTRP2; CCLE	-4.0061	4.6301	-4.5727	62.385
SNU-182	CTRP2; CCLE	-3.7406	8.2672	-5.3146	58.9662
SNU-886	CTRP2	-3.6652	17.0105	-8.7284	55.5433
SNU-878	CTRP2	-3.5822	3.4138	-3.8777	61.5517
JHH-4	GDSC2; CTRP2; CCLE	-2.8813	5.1761	-3.4738	40.383
HLE	GDSC2; CCLE	-2.7214	0.9732	-2.8298	29.4562
JHH-2	GDSC2; CTRP2; CCLE	-2.6631	12.3964	-5.7171	42.2069
Li-7	CTRP2	-2.5888	6.6142	-3.5388	55.3525
JHH-1	GDSC2; CTRP2	-2.3727	26.8782	-12.0118	44.8607
SNU-387	GDSC2; CTRP2; CCLE	-0.8228	15.2866	-5.0663	37.4617
Huh-7	GDSC2	0.2264	2.3444	-7.3124	0.0078
SNU-475	CTRP2; CCLE	0.3931	125.8433	-58.6272	49.1895
HuH-1	GDSC2; CTRP2; CCLE	0.8198	10.9538	-1.4738	28.2888
Hep-G2/C3A	GDSC2; CCLE	1.9756	14.0681	-3.4094	21.2452
JHH-6	GDSC2; CTRP2; CCLE	2.0836	11.8076	-0.5599	23.8938
SNU-449	GDSC2; CTRP2; CCLE	3.1303	10.7339	0.9798	18.2854
SK-HEP-1	GDSC2; CTRP2; CCLE	3.3382	24.0561	-5.3055	30.513
HuH-6	CTRP2	4.2339	33.9849	-9.4619	39.8849
SNU-761	CTRP2	4.2989	15.288	-0.7112	26.4931
Hep-G2	CTRP2; CCLE	4.401	35.3164	-9.9827	39.96
Hep 3B2.1-7	GDSC2; CTRP2; CCLE	5.7778	25.9543	-4.1335	28.0078

Cancer Drug Sensitivity Data Curated from 228 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H322	CTRP2; CCLE	-15.4689	24.2804	-24.0724	68.2203
DV-90	CTRP2; CCLE	-12.6987	0.9378	-13.2766	83.9029
COR-L51	CTRP2	-11.9167	-0.7632	-12.2035	85.9487
HCC1438	CTRP2	-11.5369	2.3653	-12.2779	81.023
RERF-LC-A1	CTRP2; CCLE	-10.8623	-0.0258	-11.1724	83.9883
HCC2279	CTRP2	-10.4724	10.5529	-13.3864	71.0756
SCLC-21H	CTRP2	-10.2852	11.7368	-13.6011	69.9226
LK2	CTRP2	-10.0677	-8.5979	-10.0677	99.2152
NCI-H1339	CTRP2; CCLE	-10.0127	5.7633	-11.4032	75.0602
NCI-H2286	CTRP2; CCLE	-9.9952	7.3847	-11.8437	73.3071
LUDLU-1	CTRP2; CCLE	-9.9876	13.6381	-13.9851	68.2158
NCI-H1184	CTRP2; CCLE	-9.8214	26.6127	-19.7146	61.4733
LC-2/ad	GDSC1; GDSC2	-9.1297	-6.726	-9.1402	58.2351
NCI-H841	GDSC2; CTRP2	-9.1206	13.0872	-12.8486	58.5351
VMRC-LCD	GDSC2; CTRP2; CCLE	-8.918	0.1871	-9.1362	63.881
GLC-82	CCLE	-8.8244	-5.2372	-8.8267	91.045
COLO 677	CCLE	-8.793	-6.2393	-8.7931	93.7015
LXF 289	GDSC1; GDSC2; CTRP2	-8.7685	33.8628	-21.547	54.3579
HCC15	GDSC2; CTRP2; CCLE	-8.2386	13.1038	-11.9121	56.8117
RERF-LC-MS	GDSC2; CTRP2; CCLE	-8.0099	-3.6223	-8.0134	72.0009
NCI-H1341	GDSC2; CTRP2; CCLE	-7.9823	-1.3974	-8.0374	61.3175
COR-L279	GDSC2; CTRP2	-7.932	-4.9676	-7.9321	61.6877
NCI-H2122	GDSC2; CTRP2; CCLE	-7.8829	-5.085	-7.8829	61.4744
NCI-H838	GDSC2; CTRP2	-7.7027	-3.5243	-7.7054	70.6114
NCI-H1648	GDSC1; GDSC2; CCLE	-7.6912	-5.3608	-7.6913	54.5214
NCI-H1048	GDSC2; CCLE	-7.637	-5.9161	-7.637	54.2457
Lu-99	CTRP2; CCLE	-7.6252	22.3375	-15.131	60.8534
NCI-H211	GDSC1; GDSC2; CTRP2; CCLE	-7.612	-4.9626	-7.6121	60.2816
EBC-1	GDSC2; CTRP2; CCLE	-7.6033	3.4525	-8.2305	58.2432
MOR/CPR	CTRP2; CCLE	-7.5825	-5.3093	-7.5825	89.177
NCI-H2110	GDSC2; CTRP2	-7.529	0.2889	-7.6825	67.2871
NCI-H1437	GDSC2	-7.5165	-5.5367	-7.5335	42.1634
PC-14	GDSC2; CTRP2; CCLE	-7.4847	-5.2773	-7.4847	57.8618
NCI-H510A	GDSC1; GDSC2; CTRP2	-7.4504	-5.9395	-7.4504	69.8072
Calu-6	GDSC1; GDSC2; CTRP2; CCLE	-7.4369	-1.7111	-7.4799	57.39
DMS 273	GDSC2; CTRP2	-7.3756	7.8185	-9.1216	56.2072
A-427	GDSC2	-7.369	-4.5045	-7.481	41.0479
HARA [Human squamous cell lung carcinoma]	GDSC2; CTRP2; CCLE	-7.2728	-4.3727	-7.2729	58.7825
NCI-H1703	GDSC2; CTRP2; CCLE	-7.2123	-5.765	-7.2123	58.5202
NCI-H520	GDSC2; CTRP2; CCLE	-7.1137	-0.5024	-7.1887	57.6971
NCI-H1623	GDSC2; CTRP2	-7.112	11.2745	-10.0178	54.7486
NCI-H524	GDSC1; GDSC2; CTRP2	-7.0887	0.711	-7.2601	57.3199
SBC-5	GDSC2; CTRP2; CCLE	-7.0286	-5.8822	-7.0286	57.7091
COR-L321	GDSC2	-6.9858	-4.8315	-7.0314	36.9827
NCI-H847	GDSC1; GDSC2	-6.8794	-4.2293	-6.9963	27.4089
SBC-3	GDSC2	-6.8718	-5.1956	-7.5658	6.5357
COR-L311	GDSC2	-6.8663	-5.4178	-7.4509	5.7951
HCC44	GDSC2; CTRP2; CCLE	-6.8659	-4.0737	-6.866	56.9883
NCI-H1734	GDSC2; CTRP2	-6.843	-1.3433	-6.8719	65.79
NCI-H1975	GDSC1; GDSC2; CTRP2; CCLE	-6.8189	-2.7061	-6.8228	56.7478
NCI-H3122	GDSC2	-6.7503	-3.711	-8.1999	10.1548
LK-2	GDSC2	-6.733	-4.9752	-7.5536	6.0246
Lu-135	GDSC2	-6.6648	-4.498	-7.7343	6.9648
LCLC-97TM1	GDSC2; CTRP2	-6.607	5.0978	-7.516	54.5926
RERF-LC-Sq1	GDSC2	-6.5726	-0.3563	-9.7284	18.5176
NCI-H358	GDSC2; CTRP2; CCLE	-6.5666	-2.1928	-6.5736	55.6286
NCI-H2227	GDSC2	-6.5399	0.659	-8.3715	38.8042
NCI-H1568	GDSC2; CTRP2; CCLE	-6.4932	-3.0986	-6.4941	55.3379
NCI-H522	GDSC2; CTRP2; CCLE	-6.4824	-1.8091	-6.4942	55.244
NCI-H835	GDSC2	-6.4353	10.5443	-15.0648	34.2957
LC-1/sq	GDSC2	-6.4206	-3.0836	-8.2415	9.4662
NCI-H446	GDSC1; GDSC2; CTRP2	-6.3994	-0.9972	-6.4303	54.8306
NCI-H2126	CTRP2	-6.3747	7.8717	-8.0487	66.5061
NCI-H1436	GDSC1; GDSC2	-6.3557	-4.0339	-6.4657	31.2318
NCI-H69	GDSC1; GDSC2; CTRP2	-6.2329	-0.515	-6.279	54.0876
HCC366	GDSC2; CTRP2	-6.1236	5.6751	-7.1359	59.1909
LCLC-103H	GDSC2; CTRP2; CCLE	-6.0942	-2.2063	-6.0979	53.5721
ChaGo-K-1	GDSC2; CTRP2	-6.0215	75.1069	-38.9944	51.6154
NCI-H1581	GDSC1; GDSC2; CTRP2; CCLE	-5.984	0.8244	-6.1092	52.9406
NCI-H1944	GDSC2; CTRP2; CCLE	-5.973	1.7537	-6.1964	52.8136
NCI-H2066	GDSC2	-5.9437	-1.6509	-8.5835	10.3061
IST-SL1	GDSC1; GDSC2	-5.9018	-1.8166	-6.6435	29.8722
EMC-BAC-2	GDSC2	-5.8285	-1.6403	-8.5029	9.5353
HCC4006	CTRP2; CCLE	-5.7939	77.6989	-40.0709	52.8386
NCI-H23	GDSC1; GDSC2; CTRP2; CCLE	-5.7661	-4.1482	-5.7661	52.1361
NCI-H2009	GDSC2; CTRP2; CCLE	-5.755	0.2452	-5.8266	52.0218
LOU-NH91	GDSC2; CTRP2; CCLE	-5.6968	5.3173	-6.5781	51.4837
NCI-H810	GDSC2; CTRP2; CCLE	-5.5347	30.928	-16.9992	50.3662
NCI-H2171	GDSC1; GDSC2; CTRP2	-5.4916	-0.828	-5.51	59.4474
ABC-1	GDSC2	-5.3255	-1.9721	-5.9827	23.6728
NCI-H1963	GDSC1; GDSC2	-5.3168	-2.2955	-5.8346	17.3548
SW900	CCLE	-5.2757	-0.433	-5.3766	67.7954
NCI-H1105	GDSC2; CTRP2	-5.2724	24.4369	-13.7073	52.9259
COR-L23	GDSC2; CCLE	-5.264	0.1061	-5.4248	42.4412
NCI-H526	GDSC1; GDSC2	-5.2445	-2.3606	-5.7325	16.6886
CPC-N	GDSC1; GDSC2	-5.224	-1.138	-6.2173	18.7254
EMC-BAC-1	GDSC2	-5.2032	4.4719	-8.8796	34.5301
LB647-SCLC	GDSC1; GDSC2	-5.1414	-0.3048	-6.5094	25.8875
NCI-H1876	GDSC1; GDSC2	-5.0089	-2.3056	-5.5026	14.9574
NCI-H1792	GDSC2; CTRP2; CCLE	-4.89	1.1625	-4.9921	48.3246
NCI-H82	GDSC1; GDSC2	-4.7879	0.0199	-6.3129	17.8897
CAL-12T	GDSC2; CTRP2; CCLE	-4.6051	5.7022	-5.4861	53.9334
NCI-H1155	GDSC1; GDSC2; CTRP2; CCLE	-4.5964	-1.958	-4.5967	46.9728
NCI-H2228	GDSC2; CTRP2; CCLE	-4.2014	7.9278	-5.9579	44.5162
COR-L303	GDSC2	-4.1977	2.8799	-7.1798	25.2291
HCC827	GDSC2; CTRP2; CCLE	-4.0622	4.1736	-4.5365	45.1222
NCI-H1304	GDSC1	-4.0604	-1.148	-5.0542	16.9367
SK-MES-1	GDSC2; CTRP2; CCLE	-4.0566	7.799	-5.5038	45.7782
Lu-139	GDSC1	-4.0376	-1.0388	-5.0852	17.0637
NCI-H748	GDSC1; GDSC2	-3.9789	2.9873	-7.0184	23.9821
Ms-1	GDSC1; GDSC2	-3.9441	-1.8581	-4.603	7.8212
NCI-H2141	GDSC1; GDSC2; CTRP2	-3.8366	2.2712	-3.9912	43.8409
NCI-H647	GDSC2; CTRP2; CCLE	-3.7305	59.2686	-29.0964	50.0943
NCI-H1651	GDSC2; CTRP2; CCLE	-3.6793	2.6907	-3.8752	43.2165
Lu-134-A	GDSC1; GDSC2	-3.6106	2.5336	-6.4716	20.18
DMS 114	GDSC1; GDSC2; CTRP2; CCLE	-3.5973	1.065	-3.642	42.6408
HCC33	GDSC1; GDSC2	-3.5203	1.0227	-5.6397	15.346
Hs 229.T	CCLE	-3.4138	12.707	-7.8652	51.9164
HCC1588	CTRP2	-3.3338	0.2601	-3.3443	62.171
COLO 699	CTRP2; CCLE	-3.3322	1.5022	-3.3934	61.5826
NCI-H1836	GDSC1; GDSC2	-3.3219	1.1377	-5.5289	14.0918
IST-SL2	GDSC1; GDSC2	-3.3177	0.8474	-5.3803	9.964
NCI-H290	GDSC2	-3.2645	2.3957	-6.133	17.1089
NCI-H1694	GDSC1; GDSC2; CTRP2; CCLE	-3.195	5.0131	-3.7771	41.6724
NCI-H209	GDSC1; GDSC2; CTRP2	-3.1631	4.8952	-3.8723	39.1932
NCI-H250	GDSC2	-3.0518	3.4601	-6.4905	18.364
SBC-1	GDSC1; GDSC2	-3.024	1.4108	-5.421	12.5911
COLO 668	GDSC1; GDSC2; CTRP2	-2.9611	1.794	-3.0276	39.8842
SHP-77	GDSC1; GDSC2; CTRP2; CCLE	-2.9381	-1.727	-2.9381	39.652
NCI-H187	GDSC1	-2.9294	2.8922	-6.0844	19.4092
NCI-H889	CTRP2	-2.9268	19.8961	-9.2787	53.3779
NCI-H740	GDSC2	-2.8688	3.3073	-6.2669	16.6854
NCI-H1355	GDSC1; GDSC2; CTRP2; CCLE	-2.7901	17.2362	-7.9358	43.9526
COR-L32	GDSC2	-2.7784	2.5541	-5.8202	10.6686
NCI-H2085	GDSC2; CTRP2; CCLE	-2.6197	9.187	-4.4232	40.8658
NCI-H2869	GDSC2	-2.5421	2.6605	-5.6907	12.625
NCI-H64	GDSC1; GDSC2	-2.5234	1.2854	-4.9728	6.4609
NCI-H2081	GDSC1; GDSC2; CTRP2	-2.5161	7.6934	-3.7952	45.5608
A-549	GDSC2; CTRP2; CCLE	-2.3457	12.746	-5.529	41.2892
NCI-H650	GDSC2; CTRP2; CCLE	-2.3096	138.8123	-67.4237	48.8461
NCI-H2804	GDSC2	-2.1882	15.6347	-11.8728	32.4727
Lu-65	GDSC1; GDSC2; CTRP2	-2.0758	10.7181	-4.4208	39.5033
NCI-H2023	GDSC2; CTRP2; CCLE	-2.054	14.1033	-5.8025	40.8651
SW1271	GDSC2; CTRP2; CCLE	-1.8824	12.7988	-5.4641	38.1253
SW1573	GDSC2; CCLE	-1.819	8.1524	-4.2046	30.5763
NCI-H2810	GDSC2	-1.681	7.6344	-7.4999	19.3798
NCI-H345	GDSC1; GDSC2	-1.6752	4.8103	-6.0842	12.9138
NCI-H2461	GDSC2	-1.6608	10.7033	-11.5994	15.6706
KNS-62	GDSC2; CTRP2; CCLE	-1.5879	6.7333	-2.4828	35.4695
NCI-H146	GDSC2	-1.547	7.572	-7.3698	18.5166
NCI-H292	GDSC2; CTRP2	-1.5288	44.7518	-19.9337	47.561
NCI-H2135	GDSC1; GDSC2	-1.2636	6.8082	-6.7644	15.3544
NCI-H1666	GDSC1; GDSC2; CTRP2; CCLE	-1.0684	10.3293	-3.1979	35.4607
NCI-H2029	GDSC2; CTRP2	-0.9034	15.8268	-5.3919	42.1658
NCI-H2818	GDSC2	-0.8391	2.3892	-7.6763	0.2807
NCI-H196	GDSC2; CTRP2	-0.8269	16.2826	-5.5222	37.9804
NCI-H2087	GDSC2; CTRP2; CCLE	-0.6159	17.1108	-5.6917	37.742
NCI-H1993	GDSC2	-0.5852	6.7918	-9.2365	4.8487
NCI-H1573	GDSC2; CTRP2; CCLE	-0.5752	22.3353	-8.1111	39.8374
NCI-H596	GDSC2	-0.57	2.856	-7.7404	0.3145
NCI-H2170	GDSC2; CTRP2; CCLE	-0.5622	107.8617	-50.4694	47.6209
NCI-H2803	GDSC2	-0.5621	5.6967	-5.7913	8.8704
NCI-H1781	GDSC2	-0.4434	2.8363	-7.6902	0.2331
Lu-99A	GDSC2	-0.3314	2.3965	-7.5083	0.0769
COR-L88	GDSC1; GDSC2; CTRP2	-0.325	10.3498	-2.4198	32.4968
PaCa-3	GDSC2	-0.3119	4.1866	-8.1089	0.9046
NCI-H1688	GDSC2	-0.3069	3.3766	-7.8249	0.3786
COR-L95	GDSC1; CTRP2	-0.2108	15.7554	-4.6638	42.6148
EPLC-272H	GDSC2; CTRP2	-0.2107	47.3364	-20.021	44.2955
NCI-H2795	GDSC2	-0.1871	5.3264	-8.4771	1.8152
NCI-H2731	GDSC2	-0.1066	3.2163	-7.7021	0.1997
NCI-H2347	GDSC2	-0.1006	2.6536	-7.5161	0.0678
NCI-H2722	GDSC2	-0.0822	2.6011	-7.4932	0.0567
NCI-H661	GDSC2; CTRP2; CCLE	-0.0554	15.1136	-4.2146	34.8172
NCI-H2030	GDSC2; CTRP2; CCLE	0.0729	24.2789	-8.427	42.177
NCI-H128	GDSC1	0.0809	5.249	-5.1833	6.0626
NCI-H720	GDSC1; GDSC2	0.0889	6.9271	-5.9308	6.6923
NCI-H2405	GDSC2	0.1276	2.7266	-7.4657	0.0387
NCI-H2373	GDSC2	0.1306	3.187	-7.6134	0.1066
NCI-H2595	GDSC2	0.1362	2.7935	-7.4844	0.0445
Lu-165	GDSC1; GDSC2	0.155	2.7722	-4.146	0.4835
RERF-LC-KJ	GDSC2	0.1617	2.543	-7.3961	0.0204
SK-LU-1	GDSC2; CTRP2; CCLE	0.209	18.1633	-5.3697	35.8002
HCC78	GDSC2; CTRP2; CCLE	0.2637	10.2985	-1.7791	30.0318
NCI-H2369	GDSC2	0.2708	2.6539	-7.3966	0.0185
NCI-H1770	GDSC1; GDSC2	0.2732	2.3022	-3.9375	0.1933
NCI-H513	GDSC2	0.2787	2.6598	-7.3959	0.0183
NCI-H1693	GDSC2; CTRP2; CCLE	0.2916	13.3088	-3.0487	32.3268
UMC-11	GDSC2	0.332	3.4272	-7.6252	0.0995
DMS 53	GDSC2; CTRP2	0.367	7.1836	-0.4962	27.042
NCI-H1299	GDSC2; CTRP2; CCLE	0.3884	11.7218	-2.2507	30.7012
Sq-1	CTRP2; CCLE	0.3955	180.4645	-85.9167	49.4342
NCI-H322M	GDSC1; GDSC2	0.3973	4.6125	-4.753	1.9665
NCI-H2591	GDSC2	0.4456	3.3878	-7.5754	0.0673
NCI-H3255	GDSC2; CCLE	0.5011	15.1468	-5.2638	31.8836
NCI-H2444	GDSC2; CTRP2; CCLE	0.7875	10.9696	-1.9316	30.5266
HCC2108	CTRP2	0.869	87.0657	-38.8561	48.5203
HCC1195	CTRP2	0.8716	129.1023	-59.8466	49.0024
NCI-H1650	GDSC1; GDSC2; CTRP2; CCLE	0.9905	19.7631	-5.3767	34.3986
COR-L47	CTRP2	1.0706	38.4426	-14.466	46.345
NCI-H1793	GDSC2; CTRP2; CCLE	1.1297	17.4452	-4.1343	32.4545
NCI-H2106	CTRP2	1.2513	70.4453	-30.2326	47.8584
NCI-H460	GDSC2; CTRP2; CCLE	1.2571	13.7726	-2.287	33.1265
NCI-H441	GDSC2; CTRP2; CCLE	1.2878	13.1075	-1.9515	28.3699
T3M-10	CTRP2; CCLE	1.7751	42.5588	-15.8823	45.7107
NCI-H1838	GDSC1; GDSC2; CTRP2	1.8286	10.6002	-0.2795	23.6973
NCI-H1395	CTRP2	1.998	29.7903	-9.3491	43.3955
NCI-H1435	GDSC2; CTRP2	2.0251	16.2945	-2.722	28.5118
Calu-3	GDSC2; CTRP2; CCLE	2.2412	16.9177	-2.8149	28.3079
NCI-H2196	GDSC1; GDSC2; CTRP2	2.3141	14.7085	-1.6865	29.6606
NCI-H1092	GDSC1; GDSC2; CTRP2; CCLE	3.324	16.5274	-1.6069	24.1201
DMS 454	CTRP2	3.5112	19.2235	-2.7594	34.5339
NCI-H1915	GDSC2; CTRP2; CCLE	3.5113	30.8628	-8.5342	34.0081
NCI-H1755	GDSC2; CTRP2	3.8535	27.0929	-6.3571	31.1479
EKVX	GDSC1; GDSC2; CTRP2	3.9259	15.9745	-0.7804	24.4639
HCC95	CTRP2	4.1651	37.8913	-11.471	41.109
COR-L105	GDSC2; CTRP2; CCLE	4.8993	24.7287	-4.2684	26.7063
NCI-H1373	CTRP2; CCLE	5.3865	24.4611	-3.7178	32.1917
HCC2935	CTRP2; CCLE	5.9127	6.9169	5.4941	2.5807
LC-1/sq-SF	CTRP2; CCLE	6.0749	49.8351	-15.8255	40.7574
NCI-H1563	GDSC2; CTRP2; CCLE	6.2261	15.3316	1.5513	12.2098
NCI-H226	GDSC1; GDSC2; CTRP2; CCLE	6.7168	20.2387	-1.208	15.465
NCI-H1869	GDSC1; GDSC2; CTRP2; CCLE	6.7709	27.3528	-4.0106	23.8145
NCI-H2172	GDSC2; CTRP2; CCLE	6.8034	23.0736	-1.8463	22.1782
BEN	GDSC2; CTRP2	7.2176	8.1114	5.7512	0.1145
RERF-LC-Ad1	CTRP2	7.2208	8.0413	5.7776	0.1044
NCI-H727	GDSC2; CTRP2; CCLE	7.3059	25.5228	-2.6645	20.6996
DMS 79	GDSC1; GDSC2; CTRP2	7.7066	22.0886	-0.638	18.0994
HOP-92	GDSC2; CTRP2	9.0606	31.3079	-4.1701	21.4091
HCC1833	CTRP2	9.2409	27.318	-2.0602	22.6831
HOP-62	GDSC1; GDSC2; CTRP2	9.3026	24.618	-0.6868	14.2306
RERF-LC-Ad2	CTRP2	9.4758	50.7273	-13.5058	36.0064
HCC1171	CTRP2	9.5393	23.7287	-0.0815	17.3528
NCI-H2342	GDSC2; CTRP2	9.9143	19.2887	2.3026	6.3493
NCI-H2291	GDSC2; CTRP2	10.8829	27.4864	-0.9612	14.9863
IA-LM	GDSC1; GDSC2; CTRP2; CCLE	12.7166	30.3394	-1.0941	11.8899
Calu-1	CTRP2; CCLE	14.2778	44.8209	-6.9847	24.8264
Hs 888.Lu	CTRP2	3.2579	48.7553	-17.6754	44.3881

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1; GDSC2	-2.0034	3.0585	-5.4646	7.7995

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SYO-1	CTRP2	-12.6023	13.8595	-16.8695	71.0554
H-STS	CTRP2	-9.6991	-4.8694	-9.7025	92.1008
P-STS	CTRP2	-5.0547	85.3783	-43.2136	52.1756

Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	-7.2467	817.7306	-410.9271	50.3852
MCAS	CTRP2; CCLE	-12.3068	-2.8321	-12.4275	89.5171
COV644	CTRP2	-8.6814	42.3417	-25.4726	57.6468
OC 314	GDSC2; CTRP2; CCLE	-8.0672	-5.8023	-8.0672	62.2925
ONCO-DG-1	CTRP2; CCLE	-7.7621	0.8403	-7.9859	78.3601
OC 315	CCLE	-7.2235	-5.0978	-7.2235	86.0793
TOV-112D	GDSC2; CTRP2; CCLE	-7.2017	-4.2522	-7.2018	58.4682
A2780	GDSC2; CTRP2; CCLE	-7.1772	-2.0059	-7.1942	58.2156
OVCAR-8	GDSC2; CTRP2; CCLE	-7.1657	-4.8994	-7.1657	58.314
JHOS-4	GDSC2; CCLE	-7.161	1.0596	-7.6259	59.7763
Caov-3	GDSC2; CTRP2	-7.0196	48.3958	-27.3552	52.8388
OVK18	GDSC2; CTRP2	-6.7923	3.5422	-7.4963	60.8093
OC 316	CCLE	-6.6902	-5.3945	-6.6902	83.0402
OVCAR-3	GDSC2; CCLE	-6.1268	-1.1957	-6.2024	46.632
SNU-8	CTRP2	-5.7426	6.8386	-7.0445	65.9131
COV504	CCLE	-5.2447	5.9361	-6.9412	60.6076
COV434	CTRP2	-5.1373	45.8657	-23.8104	53.9176
SK-OV-3	GDSC2; CTRP2; CCLE	-4.678	4.2607	-5.223	47.644
ES-2	GDSC1; GDSC2; CCLE	-3.7912	-0.4612	-3.8251	34.7186
DOV13	GDSC2; CTRP2; CCLE	-2.3334	10.5317	-4.6219	40.3603
OVCAR-4	GDSC1; GDSC2; CTRP2; CCLE	-1.8866	7.2756	-2.976	37.0402
Caov-4	GDSC2	-1.7097	4.4837	-5.9764	9.3865
SNU-119	CTRP2	-1.7008	21.607	-8.8592	50.5433
TYK-nu	GDSC2; CTRP2; CCLE	-1.3551	13.922	-5.0035	38.5171
COV362	CTRP2	-0.966	61.2547	-27.6005	49.5658
OV7	CTRP2	-0.7794	100.8428	-47.155	49.6326
IGROV-1	GDSC2; CTRP2; CCLE	-0.7111	19.8305	-7.0546	39.2321
JHOM-1	CTRP2	-0.4518	156.7716	-74.7989	49.6479
FU-OV-1	GDSC2; CTRP2; CCLE	-0.3252	11.5991	-2.9381	33.409
OVKATE	GDSC2	-0.2658	1.916	-4.0328	0.3366
OAW28	GDSC2; CTRP2	-0.0496	13.893	-3.6566	33.9906
TOV-21G	GDSC2; CTRP2; CCLE	0.165	14.5462	-3.7348	33.6794
JHOC-5	CTRP2	0.4447	170.1967	-80.7437	49.384
ES2	CTRP2	0.7771	10.9309	-1.5083	40.1076
EFO-21	GDSC2; CTRP2; CCLE	0.8459	16.275	-3.8578	32.5578
EFO-27	GDSC2; CTRP2; CCLE	1.4178	32.4365	-11.1812	41.4899
OAW42	GDSC2; CTRP2	2.6127	10.1418	0.7252	19.8263
OVCAR-5	GDSC2; CTRP2	2.9678	18.0644	-2.6892	26.8612
Kuramochi	GDSC1; GDSC2; CTRP2; CCLE	3.0005	13.9482	-0.6622	22.5492
RMG-I	GDSC2; CTRP2	3.2154	14.9088	-0.9207	22.7885
COV318	CCLE	3.2394	19.1434	-4.8731	31.0653
JHOS-2	GDSC2; CTRP2; CCLE	3.2474	35.9508	-11.2993	39.0273
OV56	GDSC2; CTRP2	4.1294	10.9116	1.8756	14.3002
HEY A8	CTRP2; CCLE	4.708	68.5899	-27.0091	44.3178
OVMANA	CCLE	4.712	21.6307	-4.9299	28.1457
OVTOKO	GDSC2; CTRP2; CCLE	4.7631	18.3845	-1.2235	21.0855
OVISE	GDSC2; CTRP2	7.7364	8.8682	5.6778	0.0836
OVSAHO	CTRP2; CCLE	8.145	32.4652	-5.4589	30.2009
OV-90	GDSC2; CTRP2; CCLE	8.7827	10.5433	5.476	0.1141
SNU-840	CTRP2	12.8815	43.9893	-7.5756	27.0584

Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	8.0871	9.364	5.633	0.1135
TE 617.T	CTRP2; CCLE	-12.5544	2.7486	-13.4575	81.3745
TTC-709	CTRP2	-9.7899	35.647	-23.387	59.8321
BT-16	CTRP2	-9.1066	13.1539	-12.859	67.3334
VA-ES-BJ	GDSC1; GDSC2	-7.6505	-5.2117	-7.6932	32.9101
KYM-1	GDSC2; CTRP2; CCLE	-7.5141	-3.1253	-7.5186	59.77
HT-1080	GDSC2; CTRP2; CCLE	-7.4281	-2.9503	-7.4336	59.3858
GCT	GDSC2; CTRP2; CCLE	-7.3946	-0.0695	-7.5109	58.684
Hs 729.T	CTRP2; CCLE	-7.3659	13.3326	-11.0699	64.4868
G-401	GDSC2; CTRP2; CCLE	-7.3321	-3.4228	-7.3341	59.0106
G-402	GDSC2; CTRP2; CCLE	-7.2117	2.0139	-7.5546	57.411
MFH-ino	GDSC1; GDSC2	-7.0166	-4.1641	-7.1557	28.5223
Rh41	GDSC2; CTRP2	-6.729	-4.9929	-6.729	56.3867
A-204	GDSC2; CTRP2; CCLE	-6.6253	12.1907	-9.8396	53.4295
Hs 633.T	GDSC2	-6.5319	-4.592	-7.5781	5.5972
STS-0421	GDSC2	-6.4773	-2.8668	-6.8997	33.6604
SW982	GDSC1; GDSC2; CTRP2	-6.1021	-0.8342	-6.1322	53.5544
Rh30	GDSC2; CCLE	-5.6898	-1.3436	-5.7381	44.3992
RD	GDSC2; CTRP2; CCLE	-5.5746	6.8994	-6.8792	50.9815
RKN	GDSC2; CCLE	-5.0804	-1.6043	-5.0995	41.2512
EW-8	GDSC1; GDSC2	-4.7788	-1.0434	-5.808	15.6204
SW872	GDSC1; GDSC2	-4.4365	-2.349	-4.8812	10.4863
SK-UT-1	GDSC1; GDSC2; CTRP2	-1.0256	63.984	-29.0095	46.4525
SK-LMS-1	GDSC1; GDSC2; CTRP2; CCLE	-0.8993	15.8245	-5.3867	37.9803
TE 441.T	GDSC1; GDSC2; CTRP2	-0.2387	11.8935	-2.9735	37.8732
MES-SA	GDSC2; CTRP2; CCLE	-0.1397	235.9416	-114.0974	48.8048
SW684	GDSC1; GDSC2	0.064	1.9701	-3.8981	0.1353
Tm87-16	CTRP2	2.3845	35.2917	-11.731	43.7446
Rh18	CTRP2	5.4584	6.1846	5.3618	4.2493

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
L3.3	CTRP2; CCLE	-8.9645	-0.6883	-9.1429	82.0042
PANC-1	CTRP2	-8.3199	37.2952	-22.7227	58.1
QGP-1	GDSC2; CTRP2; CCLE	-7.9263	23.2983	-15.8652	57.245
PL45	CCLE	-7.8207	7.1454	-10.1533	66.6811
KP-4	GDSC2; CTRP2; CCLE	-7.4578	-3.9458	-7.4585	59.5824
PK-1	CCLE	-7.268	2.7377	-8.1353	70.4402
KP-1NL	CCLE	-6.3299	3.4586	-7.3109	66.7116
PaTu 8988t	GDSC2	-5.8622	-2.1986	-6.4654	21.5726
PSN1	GDSC1; GDSC2; CTRP2; CCLE	-5.3053	16.3159	-10.1198	50.0528
BxPC-3	GDSC2; CTRP2; CCLE	-5.0678	1.35	-5.1951	49.092
Panc 03.27	GDSC2; CTRP2; CCLE	-5.017	1.4775	-5.1539	48.879
PaTu 8988s	CTRP2	-4.9413	99.6944	-50.2237	51.8226
KP-1N	GDSC2; CCLE	-4.3946	2.1952	-4.8653	38.6993
HPAC	GDSC2; CTRP2; CCLE	-4.3675	3.4524	-4.7302	46.287
KCI-MOH1	CCLE	-4.2606	22.2809	-13.2025	52.9179
PL4	GDSC2	-4.026	0.3105	-5.7538	13.1553
MIA PaCa-2	GDSC2; CTRP2; CCLE	-3.8161	4.6336	-4.3668	44.1879
MZ-PC-1	GDSC1; GDSC2	-3.4056	5.3157	-7.688	24.8848
DAN-G	GDSC2; CTRP2	-3.2677	15.9786	-7.868	44.952
HuP-T4	GDSC2; CTRP2; CCLE	-2.9079	5.3251	-3.7124	38.2415
Panc 10.05	GDSC2; CTRP2; CCLE	-2.8333	14.1934	-6.6481	43.293
KP-3	GDSC2; CTRP2; CCLE	-1.7513	5.1943	-2.2471	35.4241
PK-45H	CTRP2; CCLE	-1.1001	54.7259	-24.4798	49.6477
SU.86.86	GDSC2; CTRP2; CCLE	-0.3576	10.8494	-3.0446	31.0064
SW1990	GDSC2; CTRP2; CCLE	-0.257	11.1669	-2.6851	32.8284
Panc 02.03	GDSC2; CTRP2; CCLE	0.1858	13.6275	-3.2989	32.9531
HPAF-II	GDSC2; CTRP2; CCLE	0.2266	12.1928	-2.6221	31.7143
Panc 08.13	GDSC2; CTRP2	0.3112	14.392	-3.5177	33.0539
TCC-Pan2	CTRP2	0.6988	35.1135	-13.1545	46.6227
CFPAC-1	GDSC2; CTRP2	1.0174	13.1807	-2.2566	29.4789
AsPC-1	GDSC2; CTRP2; CCLE	1.1136	14.9475	-2.9736	30.6093
Capan-1	GDSC2; CTRP2	1.7125	18.8766	-4.2623	31.6175
PK-59	CTRP2; CCLE	2.0859	26.4469	-8.2124	41.2553
KP-2	GDSC2; CTRP2; CCLE	2.2584	16.86	-2.7707	28.1976
SUIT-2	GDSC2; CTRP2; CCLE	2.5829	9.6053	0.9303	19.3597
Panc 05.04	CTRP2	3.2233	26.2762	-6.509	39.4461
HuP-T3	GDSC2; CTRP2; CCLE	3.2333	19.8194	-3.3063	27.5539
Hs 766T	GDSC2; CCLE	3.4042	16.9435	-3.6379	19.5701
PaTu 8902	GDSC2; CTRP2; CCLE	4.2185	20.1245	-2.5697	24.6834
Panc 04.03	GDSC2; CTRP2; CCLE	5.3445	19.5194	-1.2848	20.394
Capan-2	GDSC2; CTRP2; CCLE	6.3481	22.3233	-1.8434	20.2467
SNU-410	CTRP2	7.0126	9.8905	4.8561	3.4062
SNU-213	CTRP2	8.7986	33.3428	-5.3829	29.1657
YAPC	GDSC2; CTRP2	9.1328	28.429	-2.6898	18.6366

Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IST-Mes2	CCLE	-7.5987	-3.6602	-7.6084	84.2379
NCI-H2452	GDSC2; CTRP2; CCLE	-5.5998	2.6392	-6.0147	49.2463
NCI-H28	GDSC2; CTRP2; CCLE	-4.5882	-0.2459	-4.6063	46.9563
NCI-H2052	GDSC2; CCLE	-3.6083	3.8304	-4.4546	35.6259
MSTO-211H	GDSC1; GDSC2; CTRP2; CCLE	-3.0472	4.5355	-3.5101	40.8932
MPP 89	GDSC1; GDSC2; CTRP2; CCLE	-1.8277	7.3925	-2.9493	36.8519
IST-Mes1	GDSC1; GDSC2; CTRP2; CCLE	4.5303	18.3775	-1.4253	21.8701
ACC-MESO-1	CTRP2	6.3255	9.9328	4.3292	6.6843
JL-1	CTRP2	9.5689	32.683	-4.4638	26.7105

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
22Rv1	GDSC2; CTRP2; CCLE	-5.8877	-1.4238	-5.8991	52.6521
DU145	GDSC2; CTRP2; CCLE	-4.7009	29.2542	-15.3957	49.0996
PC-3	GDSC2; CCLE	-3.9964	3.2063	-4.6927	37.1963
LNCaP clone FGC	GDSC1; GDSC2; CTRP2	-2.7885	3.2277	-2.9978	39.3849
VCaP	GDSC1; GDSC2; CTRP2	-2.1273	17.9987	-7.6103	42.3936
NCI-H660	GDSC2	0.1538	2.0422	-3.9251	0.1498
PaCa-3	CTRP2	9.3106	62.7985	-19.6588	39.1966

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-15	CTRP2	-7.3555	-6.9639	-7.3555	89.2718
A-253	GDSC1; GDSC2; CTRP2; CCLE	-2.5038	7.1316	-3.6026	39.5506

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1; GDSC2	-8.6919	-7.2281	-8.6923	54.0417

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuG1-N	CTRP2	-14.4682	9.0965	-17.2439	76.3204
SH-10-TC	CTRP2; CCLE	-10.8519	19.3544	-17.1851	66.0882
GSS	CTRP2	-9.9347	1.0622	-10.3297	81.3015
HGC-27	GDSC2; CTRP2; CCLE	-9.638	13.1972	-13.444	59.4465
BGC-823	CCLE	-9.4687	-5.4045	-9.473	92.1581
SNU-16	GDSC1; GDSC2; CTRP2; CCLE	-8.3894	-7.2127	-8.3894	63.7162
AZ-521	CCLE	-8.1464	-2.62	-8.2055	83.0413
IM95	GDSC2; CTRP2; CCLE	-7.9079	-4.3036	-7.9086	61.5564
NUGC-3	GDSC2; CTRP2; CCLE	-7.8166	-2.2402	-7.838	60.8897
TMK-1	GDSC2	-7.6215	-5.2177	-7.6637	43.2989
SNU-620	CTRP2	-7.6059	-6.0537	-7.6059	90.2996
ECC10	GDSC2; CTRP2	-7.4904	17.1855	-12.7637	54.5259
NCC-StC-K140	CTRP2	-7.3163	19.0135	-13.3597	61.6226
SK-GT-2	GDSC2	-7.0342	-4.2629	-8.1734	10.876
RF-48	GDSC1; GDSC2	-6.9585	-5.7747	-6.9596	27.5602
TGBC11TKB	GDSC2	-6.8245	-5.4454	-7.3995	5.3368
SNU-601	CTRP2	-6.8217	19.6212	-13.1127	60.6297
23132/87	GDSC2; CTRP2	-6.7433	-5.7024	-6.7433	54.4385
NUGC-4	GDSC2; CTRP2; CCLE	-6.4967	0.1213	-6.5889	55.1109
ECC12	GDSC2; CTRP2	-6.2597	-4.0558	-6.2597	63.6437
SNU-5	GDSC1; GDSC2; CTRP2	-6.0434	-2.5253	-6.0451	53.3541
MKN28	GDSC2	-6.0046	-3.1874	-7.8726	6.1032
SNU-216	CTRP2	-5.5433	22.9929	-13.3169	57.5896
NCI-N87	GDSC2; CTRP2; CCLE	-4.9801	5.0879	-5.7399	48.8742
Fu97	GDSC2; CCLE	-4.7413	5.3932	-6.2047	41.775
RERF-GC-1B	GDSC2; CCLE	-4.7191	1.7192	-5.1121	40.145
HSC-39	GDSC1; GDSC2	-4.6088	-1.2319	-5.5515	13.9853
OCUM-1	GDSC2; CTRP2; CCLE	-3.4028	13.6951	-7.0309	44.8574
SCH	GDSC1; GDSC2	-3.2293	-0.4692	-4.6486	8.4151
GCIY	GDSC1; GDSC2; CCLE	-2.9628	1.0703	-3.1001	30.76
Hs 746.T	GDSC2; CTRP2; CCLE	-1.5094	31.0563	-13.2049	43.9571
MKN74	CTRP2; CCLE	-0.8301	80.8218	-37.2171	49.5772
SNU-1	GDSC1; GDSC2; CTRP2; CCLE	0.3189	13.9203	-3.2959	32.6829
MKN1	GDSC2; CTRP2	0.4692	16.3614	-4.2688	33.8741
AGS	GDSC2; CTRP2	1.5007	14.1991	-2.2426	28.5469
SNU-719	CTRP2	5.9286	35.9893	-9.0247	37.1159
LMSU	CTRP2	6.0966	30.0979	-5.9389	33.9223
KATO III	GDSC2; CTRP2	6.1493	18.8124	-0.2524	16.9182
MKN7	GDSC2; CTRP2; CCLE	6.9772	38.1044	-9.2151	30.4853
SNU-668	CTRP2	7.0551	49.2437	-14.7189	39.2208
MKN45	GDSC2; CTRP2; CCLE	7.2148	8.3323	5.667	0.2143
KE-39	CTRP2; CCLE	11.449	43.2612	-8.2743	29.4558
SNG-M	GDSC2; CTRP2; CCLE	-8.2931	-1.8307	-8.3377	62.6434
SNU-685	CTRP2	1.2982	82.0314	-35.9733	48.1302
SNU-1077	CTRP2	12.329	31.0731	-1.6993	17.7309

Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
FTC-238	CTRP2	-16.0303	-1.4989	-16.4842	88.5233
SW579	CTRP2; CCLE	-8.7979	4.0359	-9.6525	75.4151
B-CPAP	GDSC2; CTRP2; CCLE	-8.4391	0.9278	-8.7153	61.9719
KMH-2	GDSC2	-7.334	-4.5039	-7.4435	40.6961
IHH-4	GDSC2	-6.5795	-4.3375	-7.7439	6.7795
HTC-C3	GDSC2	-6.5459	-3.7092	-8.0304	8.4927
CAL-62	GDSC2; CTRP2	-5.2114	3.6698	-5.6821	49.7231
8505C	GDSC2; CTRP2; CCLE	-5.1911	8.9875	-7.1307	49.7162
8305C	GDSC2; CTRP2; CCLE	-4.3742	5.2083	-5.2796	44.5134
K5	GDSC1; GDSC2	-3.8897	0.3439	-5.6268	12.4416
TT	GDSC2; CTRP2	-2.9151	12.799	-6.1476	43.1444
FTC-133	GDSC2; CTRP2	-1.8479	32.6684	-14.3061	44.7779
ML-1 [Human leukemia]	GDSC2; CTRP2	-1.5964	16.4125	-6.8117	43.0528
BHT-101	GDSC2; CTRP2	-0.4963	4.2379	-0.694	29.3141
ASH-3	GDSC2	-0.0635	1.9739	-7.287	0.0077
WRO	GDSC2	0.0943	2.8716	-7.5231	0.0612
CGTH-W-1	GDSC1; GDSC2; CTRP2	0.7845	10.126	-1.1613	27.6899
TT2609-C02	GDSC2; CTRP2; CCLE	4.9339	25.3278	-4.5377	27.0874

Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
PE/CA-PJ34 (clone C12)	CTRP2	-17.1332	4.7271	-18.9028	81.9859
BICR 6	CTRP2	-16.113	13.1298	-20.3846	74.5561
PE/CA-PJ49	CTRP2	-14.9522	-2.4864	-15.2257	89.6315
PE/CA-PJ15	GDSC2; CTRP2	-9.514	17.7087	-15.1004	61.1412
BICR 56	CTRP2	-9.3769	25.7686	-18.4433	61.9208
YD-10B	CTRP2	-8.9964	-5.4809	-8.9967	92.714
BICR 22	GDSC2; CTRP2	-8.7888	-0.9292	-8.9002	64.0457
PCI-06A	GDSC2	-8.7773	-5.6099	-8.8414	54.4502
JHU-011	GDSC2	-8.6761	-4.2857	-8.933	53.1579
BB30-HNC	GDSC1; GDSC2	-8.5185	-7.2448	-8.5186	52.3105
CAL-27	GDSC2; CTRP2; CCLE	-8.5065	-6.3959	-8.5065	64.2322
KON	GDSC2	-8.4741	-5.3127	-8.5521	51.5993
JHU-029	GDSC2	-8.0754	-3.4746	-8.4686	48.0914
KOSC-2	GDSC2	-7.9636	-5.2231	-8.0226	46.7049
SCC-25	GDSC2; CTRP2; CCLE	-7.8592	2.0063	-8.2478	66.8817
HO-1-N-1	GDSC2	-7.85	-5.6532	-8.3191	14.7293
PCI-15A	GDSC2	-7.7377	-4.8063	-7.8318	44.5858
Detroit 562	GDSC2; CTRP2; CCLE	-7.518	-2.2052	-7.5357	59.663
Ca9-22	GDSC2	-7.4955	-5.6794	-7.9408	11.0777
HO-1-u-1	GDSC2	-7.3633	-3.6671	-8.7673	15.6246
DOK	GDSC2	-7.248	-5.2874	-7.8737	9.7413
OSC-19	GDSC2	-7.1873	-1.4553	-8.1647	41.7382
SNU-1076	CTRP2	-7.101	-0.4462	-7.179	79.122
PCI-04B	GDSC2	-6.8548	0.3265	-8.5476	40.7442
CAL-33	GDSC2; CTRP2	-6.7863	-0.7241	-6.8386	56.414
NCI-H3118	GDSC2	-6.6993	2.5319	-11.2781	25.6941
BICR 10	GDSC2	-6.6082	-4.6677	-7.6023	5.9656
SAS	GDSC2	-6.5872	-3.4369	-8.2004	9.6781
LB771-HNC	GDSC1; GDSC2	-5.1169	-2.0671	-5.7121	16.2005
SAT [Human HNSCC]	GDSC2	-4.797	3.735	-10.3862	17.0176
SCC-4	GDSC2; CTRP2	-4.7522	5.8738	-5.692	48.0711
Hs 840.T	CCLE	-4.6074	14.7457	-9.9935	54.876
SNU-899	CTRP2	-3.3355	17.3999	-8.5638	54.7071
HSC-3	GDSC2; CTRP2	-2.0655	14.2094	-5.8602	40.9419
SCC-9	GDSC2; CTRP2; CCLE	-1.5542	46.0231	-20.5839	45.801
BICR 78	GDSC2	-0.7209	3.7931	-8.1246	1.1136
JHU-022	GDSC2	-0.5593	4.702	-8.3961	1.7927
BICR 16	CTRP2	-0.3598	221.0727	-106.8521	49.727
SKN-3	GDSC2	-0.3436	3.1021	-7.7449	0.2802
BHY	GDSC2; CTRP2	-0.3275	16.5194	-5.6135	39.0782
BICR 18	CTRP2	-0.19	28.4954	-10.7223	47.6332
PCI-30	GDSC2	-0.1586	3.4921	-7.8122	0.3322
SCC-15	GDSC1; GDSC2	-0.1022	5.7774	-5.5213	5.2914
UPCI-SCC-090	GDSC2	0.0304	2.6309	-7.4663	0.0421
OSC-20	GDSC2	0.2918	4.8266	-8.1099	0.7011
YD-8	CTRP2	0.3671	40.9867	-16.3576	47.5635
HSC-2	GDSC2; CTRP2; CCLE	0.3767	160.6219	-76.0167	48.065
BB49-HNC	GDSC1; GDSC2	0.3982	3.0533	-4.1536	0.4197
BICR 31	GDSC2; CTRP2	1.9073	64.1632	-26.5308	45.1836
HSC-4	GDSC2; CTRP2	2.6027	35.7604	-11.7709	37.76
SNU-46	CTRP2	5.663	32.5591	-7.5321	36.243
SNU-1041	CTRP2	5.9082	26.4746	-4.2844	32.0963
PE/CA-PJ41 (clone D2)	CTRP2	8.7556	45.6193	-11.5315	35.4512
FaDu	GDSC2; CTRP2; CCLE	10.8959	32.7058	-3.4911	18.2987

Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SCaBER	CTRP2; CCLE	-16.5409	2.317	-17.6951	84.1779
VM-CUB-1	CTRP2	-12.5034	9.477	-15.229	74.2477
U-BLC1	CTRP2	-10.6802	23.0657	-18.5852	64.3123
UM-UC-1	CTRP2	-9.9489	720.9614	-364.8277	50.6379
BC-3C	CTRP2	-9.4713	34.3247	-22.4557	59.8031
5637	GDSC2; CTRP2; CCLE	-8.114	-5.9644	-8.114	62.4996
RT-112	GDSC2; CTRP2; CCLE	-8.044	-6.4034	-8.044	60.4451
647V	GDSC2; CTRP2	-7.026	1.0285	-7.2277	57.0052
SW1710	GDSC2; CTRP2	-6.6857	1.4133	-6.9118	55.6355
JMSU-1	CTRP2; CCLE	-6.5861	-1.7228	-6.6007	79.8655
UM-UC-3	GDSC2; CTRP2; CCLE	-5.934	23.8899	-14.1181	51.1351
RT-4	GDSC2; CTRP2; CCLE	-5.7104	4.5156	-6.5525	49.7272
SW780	GDSC2; CCLE	-5.4813	-3.0888	-5.4822	43.2543
T24	GDSC2; CTRP2; CCLE	-4.7766	2.9339	-5.0841	55.2504
639V	GDSC2; CTRP2; CCLE	-3.9133	3.1652	-4.1936	44.3153
253J	CTRP2	-3.4412	4.0133	-3.8321	60.4837
CAL-29	GDSC2; CTRP2	-1.1471	17.7124	-6.4981	39.5793
BFTC-905	GDSC2; CTRP2	-0.4102	19.8049	-6.7487	38.4033
J82	GDSC2; CTRP2; CCLE	-0.0395	15.1242	-4.2036	34.7702
KMBC-2	CTRP2; CCLE	0.2307	28.8944	-10.5257	46.8493
TCCSUP	GDSC2; CTRP2; CCLE	0.9805	21.2836	-6.1193	35.2964
253J-BV	CTRP2	1.5749	37.3064	-13.4515	45.427
HT-1376	GDSC2; CTRP2; CCLE	1.6809	18.168	-3.9507	31.1967
KU-19-19	GDSC2; CTRP2	9.3113	29.1298	-2.9016	18.8495
HT-1197	GDSC2; CTRP2; CCLE	10.4729	27.5153	-1.2617	14.3079

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HeLa	GDSC2; CTRP2	-9.4028	-3.4051	-9.4218	67.401
SW954	GDSC1; GDSC2	-8.9046	-7.0572	-8.9067	56.1381
NT2-D1	GDSC1; GDSC2	-8.5915	-6.3977	-8.6013	39.8492
TC-YIK	GDSC2	-8.37	-6.8165	-8.4834	17.9139
CAL-39	GDSC2	-8.1257	-6.4572	-8.3156	15.8827
ACC-OV7	GDSC2	-8.1026	-3.9811	-8.3751	48.2407
BPH-1	GDSC2	-6.9545	-4.8442	-7.8141	8.3649
PWR-1E	GDSC2	-6.7801	-5.1572	-7.5035	5.8525
MS751	GDSC2	-6.6795	-5.0567	-7.4674	5.3186
C-33 A	GDSC2	-6.6561	-4.5552	-7.6984	6.7118
JAR	GDSC1; GDSC2	-6.6336	-4.4359	-6.7018	33.7951
KGN	GDSC1; GDSC2	-6.5699	-2.5431	-7.0975	26.7041
UWB1.289	GDSC2	-6.4565	-3.6913	-6.6495	32.4058
OVCA433	GDSC2	-6.2793	2.8528	-9.122	39.2458
SKG-IIIa	GDSC2	-6.2567	-3.2356	-8.0371	7.7504
JEG-3	GDSC2	-6.1914	-2.2344	-6.8057	31.7909
SW962	GDSC1; GDSC2	-6.1446	-2.8558	-6.5333	30.5142
NCC-IT	GDSC1; GDSC2	-6.1004	-3.4302	-6.3196	21.9725
LB831-BLC	GDSC1; GDSC2	-5.6567	-0.0461	-7.1447	23.9098
PA-1	GDSC2	-5.6171	-1.9863	-6.2857	20.0264
Ca Ski	GDSC2	-5.5185	-0.8177	-8.6806	9.8489
PEO1	GDSC2	-5.3241	-2.5167	-5.7697	16.8894
OVMIU	GDSC2	-4.3883	0.7197	-6.2881	16.5055
NEC8	GDSC1; GDSC2	-4.1435	-0.0088	-5.6855	13.347
OMC-1 [Human cervical carcinoma]	GDSC1; GDSC2	-3.2345	2.0202	-5.8974	15.9582
OVCA420	GDSC2	-3.0615	-0.2319	-4.6556	5.7872
OV17R	GDSC2	-1.9771	3.7226	-5.796	11.8299
JHOS-3	GDSC2	-0.8132	5.9556	-6.0735	10.8008
SiSo	GDSC2	-0.4147	3.1746	-7.7941	0.3572
HEC-1	GDSC2	-0.0226	2.1063	-7.316	0.0105
SW756	GDSC2	-0.0185	3.0018	-7.6022	0.1108
SKN	GDSC2	0.0203	5.4391	-8.4346	1.5772
C-4-I	GDSC2	0.0366	3.2839	-7.6763	0.1604
HEY	GDSC2	0.0925	3.7896	-7.8255	0.3046
ME-180	GDSC2	0.099	3.8236	-7.8346	0.3148
DoTc2 4510	GDSC2	0.1048	3.0371	-7.5731	0.0849
HT-3	GDSC2	0.2743	2.6058	-7.3802	0.0157
DSH1	GDSC1; GDSC2	0.481	5.5493	-5.1014	3.0769
SiHa	GDSC2	0.5114	2.8686	-7.3882	0.0137

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