Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTJ1NH)

• Drug Name: L-serine-O-phosphate Drug Info
• Synonyms: Phosphoserine; O-phospho-L-serine; Dexfosfoserine; phosphoserine; 407-41-0; L-O-Phosphoserine; Fosforina; O-Phosphoserine; L-SOP; L-Phosphoserine; PHOSPHONOSERINE; 3-phosphoserine; L-Serine O-phosphate; Dexfosfoserine [INN]; Phosphatidalserine; 3-O-Phosphoserine; H-Ser(PO3H2)-OH; O-phosphono-L-serine; serine, O-phosphono-; (+)-L-Serine dihydrogen phosphate (ester); L-Seryl phosphate; UNII-VI4F0K069V; L-3-Phosphoserine; L-O-Serine phosphate; L-Serinephosphoric acid; H-Ser(PO)-OH; L-2-amino-3-hydroxypropanoic acid 3-phosphate; LSOP; Phosphonoserine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 68841
  ChEBI ID: CHEBI:15811
  CAS Number: CAS 407-41-0
  TTD Drug ID: DMTJ1NH

Molecule-Related Drug Atlas

Drug(s) Targeting Rhodopsin (RHO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-D-Mannose	DMF5DLW	Discovery agent	N.A.	Investigative	[1]
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[1]
Phosphonothreonine	DMTFHPI	Discovery agent	N.A.	Investigative	[1]
Beta-D-Mannose	DMHIG9K	Discovery agent	N.A.	Investigative	[1]
Hexadecanoic acid	DMWUXDZ	Discovery agent	N.A.	Investigative	[1]
NSC-88915	DM9WIHJ	Solid tumour/cancer	2A00-2F9Z	Investigative	[6]
Lauryl Dimethylamine-N-Oxide	DM3W2OE	Discovery agent	N.A.	Investigative	[1]
B-2-Octylglucoside	DMEGX8H	Discovery agent	N.A.	Investigative	[1]
(Hydroxyethyloxy)Tri(Ethyloxy)Octane	DMY6FUD	Discovery agent	N.A.	Investigative	[1]
B-Nonylglucoside	DM48VJR	Discovery agent	N.A.	Investigative	[7]

Drug(s) Targeting Phosphoinositide dependent protein kinase-1 (PDPK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AR-12	DM4RK6P	Lymphoma	2A80-2A86	Phase 1	[8]
PMID20005102C1	DMMESBW	Discovery agent	N.A.	Investigative	[9]
BX-912	DMZA45C	Discovery agent	N.A.	Investigative	[10]
BX-795	DMRIMLJ	Discovery agent	N.A.	Investigative	[10]
PHT-427	DMI96Y3	Discovery agent	N.A.	Investigative	[11]
PF-5177624	DMUOFT0	Solid tumour/cancer	2A00-2F9Z	Investigative	[12]
GSK-2334470	DM3BI7R	Solid tumour/cancer	2A00-2F9Z	Investigative	[13]

Drug(s) Targeting Protein kinase C theta (PRKCQ)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sotrastaurin acetate	DME53YS	Renal transplantation	NE84	Phase 2	[14]
RO-320432	DMFZ1YW	N. A.	N. A.	Terminated	[15]
LY-317644	DMM20PI	N. A.	N. A.	Terminated	[16]
CDE-6960	DMA0DKI	Inflammation	1A00-CA43.1	Terminated	[17]
RO-316233	DMAGLPW	Discovery agent	N.A.	Investigative	[18]
LY-326449	DMN53M4	Discovery agent	N.A.	Investigative	[19]
[2,2':5',2'']Terthiophen-4-yl-methanol	DMRQC1F	Discovery agent	N.A.	Investigative	[20]
4-[1-(4-hydroxyphenyl)-3-methyl-1-butenyl]phenol	DM8IYG1	Discovery agent	N.A.	Investigative	[21]
2-(4-Hydroxy-phenyl)-3,3-diphenyl-acrylonitrile	DMNGW1A	Discovery agent	N.A.	Investigative	[21]
[2,2':5',2'']Terthiophene-4,5''-dicarbaldehyde	DMWDNLI	Discovery agent	N.A.	Investigative	[20]

Drug(s) Targeting Metabotropic glutamate receptor 6 (mGluR6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-CCG-I	DMPZ8XH	Discovery agent	N.A.	Investigative	[22]
(1S,3R)-ACPD	DM5DOAF	Discovery agent	N.A.	Investigative	[23]
MAP4	DMUCE93	Discovery agent	N.A.	Investigative	[24]
MPPG	DMJHQ9T	Discovery agent	N.A.	Investigative	[23]
[3H]LY341495	DMGX0Y8	Discovery agent	N.A.	Investigative	[4]
alpha-methylserine-O-phosphate	DMCIH1X	Discovery agent	N.A.	Investigative	[24]
L-AP4	DMPJFGI	Discovery agent	N.A.	Investigative	[3]
PHCCC	DMNJY79	Discovery agent	N.A.	Investigative	[25]
LSP4-2022	DMBWHGP	Discovery agent	N.A.	Investigative	[26]
(S)-3,4-DCPG	DMG5BUA	Discovery agent	N.A.	Investigative	[27]

Drug(s) Targeting Metabotropic glutamate receptor 7 (mGluR7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
[3H]quisqualate	DMDQBTX	Discovery agent	N.A.	Investigative	[28]
L-CCG-I	DMPZ8XH	Discovery agent	N.A.	Investigative	[4]
(1S,3R)-ACPD	DM5DOAF	Discovery agent	N.A.	Investigative	[4]
(+)-MCPG	DMG5QJB	Discovery agent	N.A.	Investigative	[4]
MAP4	DMUCE93	Discovery agent	N.A.	Investigative	[4]
MPPG	DMJHQ9T	Discovery agent	N.A.	Investigative	[4]
[3H]LY341495	DMGX0Y8	Discovery agent	N.A.	Investigative	[4]
alpha-methylserine-O-phosphate	DMCIH1X	Discovery agent	N.A.	Investigative	[4]
L-AP4	DMPJFGI	Discovery agent	N.A.	Investigative	[4]
LSP4-2022	DMBWHGP	Discovery agent	N.A.	Investigative	[26]

Drug(s) Targeting Metabotropic glutamate receptor 8 (mGluR8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
[3H]quisqualate	DMDQBTX	Discovery agent	N.A.	Investigative	[28]
L-CCG-I	DMPZ8XH	Discovery agent	N.A.	Investigative	[5]
(1S,3R)-ACPD	DM5DOAF	Discovery agent	N.A.	Investigative	[29]
MAP4	DMUCE93	Discovery agent	N.A.	Investigative	[30]
MPPG	DMJHQ9T	Discovery agent	N.A.	Investigative	[29]
alpha-methylserine-O-phosphate	DMCIH1X	Discovery agent	N.A.	Investigative	[24]
L-AP4	DMPJFGI	Discovery agent	N.A.	Investigative	[5]
(S)-3,4-DCPG	DMG5BUA	Discovery agent	N.A.	Investigative	[27]
ACPT-I	DM264XN	Discovery agent	N.A.	Investigative	[31]
CPPG	DMVHX5T	Discovery agent	N.A.	Investigative	[30]

Drug(s) Targeting Pseudomonas Phosphomannomutase/phosphoglucomutase (Pseudo algC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-D-Glucose-6-Phosphate	DMR0EVN	Discovery agent	N.A.	Investigative	[1]
D-Mannose 1-Phosphate	DM7O1IW	Discovery agent	N.A.	Investigative	[1]
Alpha-D-Mannose-6-Phosphate	DM3NCM1	Discovery agent	N.A.	Investigative	[1]
Alpha-D-Glucose-1-Phosphate	DMU36HT	Discovery agent	N.A.	Investigative	[1]

Drug(s) Targeting Glycogen phosphorylase muscle form (GP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
URSOLIC ACID	DM4SOAW	Metabolic syndrome x	5C50-5D2Z	Phase 2	[32]
JTT-651	DMGP42Q	Type-2 diabetes	5A11	Discontinued in Phase 1	[33]
Beta-D-Glucose	DM5IHYP	Discovery agent	N.A.	Investigative	[1]
Indirubin-5-sulfonate	DM08VHZ	Discovery agent	N.A.	Investigative	[1]
Inosinic Acid	DMLR86H	Discovery agent	N.A.	Investigative	[1]
Alpha-D-Glucose-6-Phosphate	DMR0EVN	Discovery agent	N.A.	Investigative	[1]
N'-Pyridoxyl-Lysine-5'-Monophosphate	DM3ZHBO	Discovery agent	N.A.	Investigative	[1]
OLEANOLIC_ACID	DMWDMJ3	Discovery agent	N.A.	Investigative	[34]
Oleanonic acid	DMYPJC3	Discovery agent	N.A.	Investigative	[34]
Nojirimycine Tetrazole	DMYZRTB	Discovery agent	N.A.	Investigative	[7]

Drug(s) Targeting Metabotropic glutamate receptor 4 (mGluR4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
DT-1687	DMU2GP4	Parkinson disease	8A00.0	Phase 2	[35]
L-CCG-I	DMPZ8XH	Discovery agent	N.A.	Investigative	[36]
MAP4	DMUCE93	Discovery agent	N.A.	Investigative	[37]
MPPG	DMJHQ9T	Discovery agent	N.A.	Investigative	[37]
L-AP4	DMPJFGI	Discovery agent	N.A.	Investigative	[37]
PHCCC	DMNJY79	Discovery agent	N.A.	Investigative	[38]
2-methyl-6-(phenylethynyl)pyridine	DMVQK4Y	Discovery agent	N.A.	Investigative	[39]
LSP4-2022	DMBWHGP	Discovery agent	N.A.	Investigative	[26]
(S)-3,4-DCPG	DMG5BUA	Discovery agent	N.A.	Investigative	[27]
ACPT-I	DM264XN	Discovery agent	N.A.	Investigative	[40]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glycogen phosphorylase muscle form (GP)	TTZHY6R	PYGM_HUMAN	Inhibitor	[1]
Metabotropic glutamate receptor 4 (mGluR4)	TTICZ1O	GRM4_HUMAN	Agonist	[2]
Metabotropic glutamate receptor 6 (mGluR6)	TTWRP2F	GRM6_HUMAN	Agonist	[3]
Metabotropic glutamate receptor 7 (mGluR7)	TT0I76D	GRM7_HUMAN	Agonist	[4]
Metabotropic glutamate receptor 8 (mGluR8)	TT0IFKL	GRM8_HUMAN	Agonist	[5]
Phosphoinositide dependent protein kinase-1 (PDPK1)	TT9QBI6	PDPK1_HUMAN	Inhibitor	[1]
Protein kinase C theta (PRKCQ)	TT8QL1J	KPCT_HUMAN	Inhibitor	[1]
Pseudomonas Phosphomannomutase/phosphoglucomutase (Pseudo algC)	TTLP3GX	ALGC_PSEAE	Inhibitor	[1]
Rhodopsin (RHO)	TTH0KSX	OPSD_HUMAN	Inhibitor	[1]

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