Details of the Drug Reposition

General Information of This Drug (ID: DMKECZD)

Drug Name
Temozolomide   DMKECZD
Synonyms
Methazolastone; Temodal; Temodar; Temozolamide; Temozolodida; Temozolomidum; Essex brand of temozolomide; Scheringbrand of temozolomide; Temozolodida [Spanish]; Temozolomidum [Latin]; M B 39831; MB 39831; Sch 52365; M & B 39831; M&B 39831; M-39831; Sch-52365; Schering-Plough brand of temozolomide; TMZ-Bioshuttle; Temodal (TN); Temodar (TN); Temozolomide [INN:BAN]; M&B-39831; Temozolomide (JAN/USAN/INN); 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide; 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide; 3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide; 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide; 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one; TMZ
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
8 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Kidney neoplasm DISBNZTN N.A. Approved [1]
Gliosarcoma DIS985MG N.A. Approved [1]
Malignant glioma DISFXKOV 2A00.0 Approved [1]
Lung cancer DISCM4YA 2C25.0 Approved [1]
Melanoma DIS1RRCY 2C30 Approved [1]
Adenocarcinoma DIS3IHTY 2D40 Approved [1]
Central nervous system disease DISFB8P5 8A04-8D87 Approved [1]
Brain disease DIS6ZC3X 8C70-8E61 Approved [1]
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⏷ Show the Full List of 8 Indications(s)
1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Large cell carcinoma DISYMCOF N.A. Withdrawn [2]
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1 Discontinued in Phase 3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Oligoastrocytoma DISQGE8F N.A. Discontinued in Phase 3 [3]
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1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ewing sarcoma DISQYLV3 2B52 Discontinued in Phase 2 [4]
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1 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Neuroblastoma DISVZBI4 2D11.2 Investigative [1]
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References

1 Temozolomide FDA Label
2 IGF-1 Inhibitor Pasireotide Lar in Combination With the m-TOR Inhibitor Everolimus
3 Ritalin: Antiasthenic Effect of Methylphenidate (Ritalin) in Palliative Care in Cancer Patients
4 Safety Study of Renal Function in Patients With Chronic Kidney Failure Taking Lumiracoxib or Diclofenac for Arthralgia